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planemo upload commit 0d652311f9c4ccc26b27eebc44a3ae91a72e57b0
| author | rhpvorderman |
|---|---|
| date | Mon, 03 Feb 2025 13:37:26 +0000 |
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Sequence number Sequence ID Functionality V-GENE and allele V-REGION score V-REGION identity % V-REGION identity nt V-REGION identity % (with ins/del events) V-REGION identity nt (with ins/del events) J-GENE and allele J-REGION score J-REGION identity % J-REGION identity nt D-GENE and allele D-REGION reading frame CDR1-IMGT length CDR2-IMGT length CDR3-IMGT length CDR-IMGT lengths FR-IMGT lengths AA JUNCTION JUNCTION frame Orientation Functionality comment V-REGION potential ins/del J-GENE and allele comment V-REGION insertions V-REGION deletions Sequence 1 JY8QFUQ01DD1I8 No results 2 JY8QFUQ01BR14W unknown (see comment) Homsap IGHV3-16*01 ORF, or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-35*01 ORF or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 134 88.24 30/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctggattcaccttcagcaaccataacatgaact 3 JY8QFUQ01DI33C No results 4 JY8QFUQ01AHA5U No results 5 JY8QFUQ01C6E2Q No results 6 JY8QFUQ01DTOF7 No results 7 JY8QFUQ01DTQZ4 No results 8 JY8QFUQ01CH7HW No results 9 JY8QFUQ01DRIUN No results 10 JY8QFUQ01DMFB3 No results 11 JY8QFUQ01DBKZ5 No results 12 JY8QFUQ01ALILW No results 13 JY8QFUQ01DQT5M No results 14 JY8QFUQ01CU1U5 No results 15 JY8QFUQ01AZ7M4 No results 16 JY8QFUQ01BJI4T No results 17 JY8QFUQ01A8WKP No results 18 JY8QFUQ01CDRAH No results 19 JY8QFUQ01BSZTH No results 20 JY8QFUQ01COV1I No results 21 JY8QFUQ01BYN3R No results 22 JY8QFUQ01BB6L9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 121 69.81 37/53 nt 8 X X 8.X.X [1.8.X.X] null + No rearrangement found tccggattcacctttagtagttactggatgcactgggtccagggcttcttccc 23 JY8QFUQ01AK5S0 No results 24 JY8QFUQ01A3U3N No results 25 JY8QFUQ01DMJ3V No results 26 JY8QFUQ01DULTP No results 27 JY8QFUQ01DXFUU No results 28 JY8QFUQ01BDHX9 No results 29 JY8QFUQ01BFXXE No results 30 JY8QFUQ01DA0S9 No results 31 JY8QFUQ01A8RD7 No results 32 JY8QFUQ01DUD3G unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 167 94.59 35/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttggttattatggcatgagctgg 33 JY8QFUQ01BAEVW unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta 34 JY8QFUQ01C5VTQ No results 35 JY8QFUQ01DV0LO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 442 93.07 94/101 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 36 JY8QFUQ01BQV49 No results 37 JY8QFUQ01BG2BI No results 38 JY8QFUQ01DDCUU unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 709 79.73 177/222 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (79,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaatcacgttgtatctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 39 JY8QFUQ01DTYS9 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 122 69.09 38/55 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found tctggattcacctttagtaaccattggatgaactgggtccagggcttcttcccca 40 JY8QFUQ01DWUUL No results 41 JY8QFUQ01BDC06 No results 42 JY8QFUQ01DQ6VG unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga 43 JY8QFUQ01C3GCP No results 44 JY8QFUQ01A1UV9 No results 45 JY8QFUQ01CVLJY No results 46 JY8QFUQ01BAK18 No results 47 JY8QFUQ01CEPBG No results 48 JY8QFUQ01ART19 No results 49 JY8QFUQ01CA0L6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 95 57.32 47/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttcccgcaccagtcgacggtgtcgtggaactcag 50 JY8QFUQ01BLYKI No results 51 JY8QFUQ01CMHH0 No results 52 JY8QFUQ01DTU6H No results 53 JY8QFUQ01AFK93 No results 54 JY8QFUQ01CAQ1G No results 55 JY8QFUQ01DGVKY No results 56 JY8QFUQ01DTVWR No results 57 JY8QFUQ01DHF6P No results 58 JY8QFUQ01DW0GO unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 59 JY8QFUQ01B3H3U No results 60 JY8QFUQ01BG2D6 No results 61 JY8QFUQ01CU2N8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 506 82.43 122/148 nt 8 8 X 8.8.X [4.17.12.X] null + No rearrangement found Low V-REGION identity (82,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcagcctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca 62 JY8QFUQ01DPEOQ No results 63 JY8QFUQ01DVW6F No results 64 JY8QFUQ01BZICQ No results 65 JY8QFUQ01DTLA9 No results 66 JY8QFUQ01DI96Y unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 206 97.67 42/43 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccccc 67 JY8QFUQ01ASP3F No results 68 JY8QFUQ01DU9Q8 No results 69 JY8QFUQ01CUFKA No results 70 JY8QFUQ01DE7XG No results 71 JY8QFUQ01DDYY7 No results 72 JY8QFUQ01CKJ4D No results 73 JY8QFUQ01CE6UI No results 74 JY8QFUQ01B2WAW No results 75 JY8QFUQ01BZYKW No results 76 JY8QFUQ01DV6KB No results 77 JY8QFUQ01CVA7X unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 78 JY8QFUQ01BWC41 No results 79 JY8QFUQ01DPMI5 No results 80 JY8QFUQ01BZF17 No results 81 JY8QFUQ01C8FAJ No results 82 JY8QFUQ01DM452 No results 83 JY8QFUQ01BJZEA No results 84 JY8QFUQ01BKHV9 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F (see comment) 627 80.73 155/192 nt 80.21 154/192 nt 7 7 X 7.7.X [1.17.31.X] null + No rearrangement found Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcaccgtcaatagaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 85 JY8QFUQ01C942O No results 86 JY8QFUQ01CSVTG unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 87 JY8QFUQ01DVNMI No results 88 JY8QFUQ01CTXI4 No results 89 JY8QFUQ01BLB8J No results 90 JY8QFUQ01DLI1K No results 91 JY8QFUQ01CDDFH No results 92 JY8QFUQ01ANSE9 No results 93 JY8QFUQ01DTA69 No results 94 JY8QFUQ01CGH3T No results 95 JY8QFUQ01C79ZO No results 96 JY8QFUQ01BW552 No results 97 JY8QFUQ01A71P8 No results 98 JY8QFUQ01DM7US No results 99 JY8QFUQ01AUTO1 No results 100 JY8QFUQ01DFULG No results 101 JY8QFUQ01DU8HP No results 102 JY8QFUQ01CSLDE No results 103 JY8QFUQ01DJDQI unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 494 96.23 102/106 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatact 104 JY8QFUQ01CHLO2 No results 105 JY8QFUQ01C0YZ5 No results 106 JY8QFUQ01BFBEW unknown (see comment) Homsap IGHV7-81*01 ORF 119 77.5 31/40 nt 8 X X 8.X.X [1.4.X.X] null + No rearrangement found tctggattcagcctcgccacttatagtatgagttgggtcc 107 JY8QFUQ01DGR36 No results 108 JY8QFUQ01BZAA8 No results 109 JY8QFUQ01AK0R1 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 612 75.58 164/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 110 JY8QFUQ01ALF4T unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggtagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 111 JY8QFUQ01CTJBP unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 112 JY8QFUQ01BAW8J No results 113 JY8QFUQ01DSN7R No results 114 JY8QFUQ01CIMDF No results 115 JY8QFUQ01AEIQD No results 116 JY8QFUQ01ALOXD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 117 JY8QFUQ01AQN2C No results 118 JY8QFUQ01BGKOV No results 119 JY8QFUQ01DDRSG No results 120 JY8QFUQ01AHLWO unknown (see comment) Homsap IGHV3-7*01 F (see comment) 747 82.49 179/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 121 JY8QFUQ01AN0SO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 193 93.18 41/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagcaagtatgccatgagctgggtccgcca 122 JY8QFUQ01CT52V No results 123 JY8QFUQ01CWLUO No results 124 JY8QFUQ01A2ELS No results 125 JY8QFUQ01DOEGW No results 126 JY8QFUQ01CSUXL No results 127 JY8QFUQ01CT2OK No results 128 JY8QFUQ01DOFCV No results 129 JY8QFUQ01DGWX7 No results 130 JY8QFUQ01CGOFR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 126 83.33 30/36 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found tctggattcagcctcacttcctatggcatgaactgg 131 JY8QFUQ01CNLGG No results 132 JY8QFUQ01AYFAD No results 133 JY8QFUQ01BVDR4 No results 134 JY8QFUQ01DOXX1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 168 58.91 76/129 nt 8 6 X 8.6.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 135 JY8QFUQ01BDB4H No results 136 JY8QFUQ01DIGN2 unknown (see comment) Homsap IGHV7-81*01 ORF 98 76.47 26/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctggattcagcctcgccacttatagtatgagtt 137 JY8QFUQ01BIZ21 No results 138 JY8QFUQ01DB13R No results 139 JY8QFUQ01DAU01 No results 140 JY8QFUQ01BR5FT No results 141 JY8QFUQ01A37Q6 No results 142 JY8QFUQ01DUO5E No results 143 JY8QFUQ01C5YGF No results 144 JY8QFUQ01AO7LQ No results 145 JY8QFUQ01A3ZCN No results 146 JY8QFUQ01DP11J No results 147 JY8QFUQ01BJSFE No results 148 JY8QFUQ01CVDV0 No results 149 JY8QFUQ01COZ0J unknown (see comment) Homsap IGHV3-66*02 F 724 91.76 156/170 nt 90.59 154/170 nt 8 6 X 8.6.X [4.16.21.X] null - No rearrangement found in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 63 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 89 in the user submitted sequence), (cause frameshift) tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccaggaagggctggactgcgtctcagttattatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta 150 JY8QFUQ01BS64J No results 151 JY8QFUQ01CQ9CW No results 152 JY8QFUQ01DCLVR unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 87 51.94 67/129 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 153 JY8QFUQ01A1QTO No results 154 JY8QFUQ01A83B7 No results 155 JY8QFUQ01DWC5U No results 156 JY8QFUQ01BGBH9 No results 157 JY8QFUQ01DB7E1 No results 158 JY8QFUQ01DVKJB No results 159 JY8QFUQ01DG72B No results 160 JY8QFUQ01AY84U No results 161 JY8QFUQ01AEJBJ No results 162 JY8QFUQ01DB5ED No results 163 JY8QFUQ01C3EIC unknown (see comment) Homsap IGHV1-58*01 F, or Homsap IGHV1-58*02 F or Homsap IGHV3-11*01 F or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F 45 100.0 9/9 nt 2 X X 2.X.X [0.X.X.X] null + No rearrangement found ctggattca 164 JY8QFUQ01CAHKQ No results 165 JY8QFUQ01A1A0E No results 166 JY8QFUQ01BYHJD No results 167 JY8QFUQ01DOTCX No results 168 JY8QFUQ01CAYCB No results 169 JY8QFUQ01B5FJJ No results 170 JY8QFUQ01AH7DD No results 171 JY8QFUQ01BR117 No results 172 JY8QFUQ01BB0TH unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 462 70.77 138/195 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BB0TH ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 173 JY8QFUQ01CXC3R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 348 86.02 80/93 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found tctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 174 JY8QFUQ01BY61P No results 175 JY8QFUQ01A2HZI No results 176 JY8QFUQ01DAXAJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 479 82.73 115/139 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 177 JY8QFUQ01DLHM1 No results 178 JY8QFUQ01CH35Q No results 179 JY8QFUQ01A6JB1 No results 180 JY8QFUQ01A3M0Z unproductive (see comment) Homsap IGHV3-48*02 F 119 58.95 56/95 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 X X X X.X.X [X.X.31.11] CAGQWQGS#YGINVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcggggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 181 JY8QFUQ01BVB4O No results 182 JY8QFUQ01BYT51 No results 183 JY8QFUQ01DRQ90 No results 184 JY8QFUQ01CTBQK No results 185 JY8QFUQ01A8U9M unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 262 61.27 106/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (61,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg 186 JY8QFUQ01A13K0 No results 187 JY8QFUQ01B0KSX unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 138 56.06 74/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagtgactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 188 JY8QFUQ01A0UIS No results 189 JY8QFUQ01CTF2E No results 190 JY8QFUQ01C986B No results 191 JY8QFUQ01A52NX No results 192 JY8QFUQ01CP60A No results 193 JY8QFUQ01A0IDA No results 194 JY8QFUQ01BYV10 No results 195 JY8QFUQ01A1Z98 No results 196 JY8QFUQ01DWS1H unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 71.91 128/178 nt 8 8 X 8.8.X [1.16.25.X] null + No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaagggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 197 JY8QFUQ01B39DQ No results 198 JY8QFUQ01BMPRJ No results 199 JY8QFUQ01CSA7J unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 86 94.74 18/19 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found tctggattcacctttaaca 200 JY8QFUQ01ALH3Y No results 201 JY8QFUQ01B0IJE No results 202 JY8QFUQ01CCW9C No results 203 JY8QFUQ01CTHJF No results 204 JY8QFUQ01CJ0PY No results 205 JY8QFUQ01CQDYQ No results 206 JY8QFUQ01BVQA9 No results 207 JY8QFUQ01CNN0N No results 208 JY8QFUQ01CTW86 No results 209 JY8QFUQ01CY6WQ productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 210 JY8QFUQ01CFDPF No results 211 JY8QFUQ01CZBUH No results 212 JY8QFUQ01DH7FZ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-23*01 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 329 62.81 125/199 nt 8 8 X 8.8.X [1.17.32.X] null + No rearrangement found Low V-REGION identity (62,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgacttcagtagatatatcatgaattgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 213 JY8QFUQ01CQK1N No results 214 JY8QFUQ01BLRBA No results 215 JY8QFUQ01C9N72 No results 216 JY8QFUQ01CWO5P No results 217 JY8QFUQ01A9JCI No results 218 JY8QFUQ01DE0PS No results 219 JY8QFUQ01DR84G unknown (see comment) Homsap IGHV3-7*02 F 99 58.02 47/81 nt 8 1 X 8.1.X [0.17.X.X] null + No rearrangement found ctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 220 JY8QFUQ01BARRD No results 221 JY8QFUQ01C1NR2 No results 222 JY8QFUQ01AHAFH No results 223 JY8QFUQ01A26OK No results 224 JY8QFUQ01CGWCE No results 225 JY8QFUQ01DVLDK No results 226 JY8QFUQ01CJXM7 No results 227 JY8QFUQ01DS8UG No results 228 JY8QFUQ01A5YUQ No results 229 JY8QFUQ01AYPSG No results 230 JY8QFUQ01DHCTP No results 231 JY8QFUQ01C2R6X No results 232 JY8QFUQ01DCWWX unknown (see comment) Homsap IGHV3-NL1*01 F (see comment) 237 65.85 81/123 nt 8 7 X 8.7.X [1.17.8.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DCWWX ; 8 AA in Homsap_IGHV3-NL1*01), and low V-REGION identity (65,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggatcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 233 JY8QFUQ01BBIRD No results 234 JY8QFUQ01BUPUP unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 115 84.38 27/32 nt 8 X X 8.X.X [1.1.X.X] null + No rearrangement found gtctggatttaccttcagtaagttctggatgc 235 JY8QFUQ01A14E7 No results 236 JY8QFUQ01BPOEB No results 237 JY8QFUQ01BIXXS No results 238 JY8QFUQ01DEYOG No results 239 JY8QFUQ01DT1EA No results 240 JY8QFUQ01DDCTT No results 241 JY8QFUQ01C8365 No results 242 JY8QFUQ01AFEYM No results 243 JY8QFUQ01BLXFI No results 244 JY8QFUQ01CVJ8R No results 245 JY8QFUQ01DEM1N productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 78 of V-REGION: 'AG' (2 nucleotides at position 136 to 137 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcgaAGtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 246 JY8QFUQ01BJ01G No results 247 JY8QFUQ01C1OWK No results 248 JY8QFUQ01A4123 No results 249 JY8QFUQ01DBK0C No results 250 JY8QFUQ01AG8OC No results 251 JY8QFUQ01DK7J9 No results 252 JY8QFUQ01CZKX8 No results 253 JY8QFUQ01BSZE3 No results 254 JY8QFUQ01DMJ2K No results 255 JY8QFUQ01AYEJ5 unknown (see comment) Homsap IGHV4-61*02 F (see comment) 262 83.78 62/74 nt 10 X X 10.X.X [1.13.X.X] null + No rearrangement found Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgcctggatccggcagccc 256 JY8QFUQ01DCN17 No results 257 JY8QFUQ01AB5K5 No results 258 JY8QFUQ01DVMBC No results 259 JY8QFUQ01DSA05 No results 260 JY8QFUQ01CTTZZ No results 261 JY8QFUQ01C428X No results 262 JY8QFUQ01CBV3X No results 263 JY8QFUQ01DHY8X unproductive Homsap IGHV3-15*04 F 979 93.69 208/222 nt 92.79 206/222 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-15*01 F 3 8 9 X 8.9.X [1.17.38.11] CAADGCPGGTCYHG#LDMW out-of-frame + in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtggttgggccgtattgaGaagcaaaactgctggtgggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttggatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcncatgcctggtccagggcttcttcccc 264 JY8QFUQ01AV5JR unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggtggccccatcaacagtgatggtcaatattggaactggatccggcagcccgccgggaagggactggagtggatcggacatgtttacagtggtgggggtaccaattataattcgtccttcgggagtcgagtcaccatgtcattagacatgtccaacaaccagttctccctgatattgagctctgtgacggccgcagacacggccatatattactgtgcgagagaacgtggtagggcgactgccggagcgagagaccttgactcctggggccagggaatcctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccaggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 265 JY8QFUQ01DI7LG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 266 JY8QFUQ01B15JZ No results 267 JY8QFUQ01AL59V No results 268 JY8QFUQ01BL0MP No results 269 JY8QFUQ01DFOIH No results 270 JY8QFUQ01C121A unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 91 52.34 67/128 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 271 JY8QFUQ01A6J9J No results 272 JY8QFUQ01BQ44V No results 273 JY8QFUQ01BV9HI No results 274 JY8QFUQ01DEZCV No results 275 JY8QFUQ01DXIEO No results 276 JY8QFUQ01BBTMB unknown (see comment) Homsap IGHV3-13*02 F 106 54.1 66/122 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found tctggattctccttcagggaccactatattgactgggtccgccaagctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact 277 JY8QFUQ01DQ1GX No results 278 JY8QFUQ01ACHTP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 364 82.24 88/107 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found Low V-REGION identity (82,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 279 JY8QFUQ01C65ZI No results 280 JY8QFUQ01CV0X9 No results 281 JY8QFUQ01AQI9Z unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 110 53.24 74/139 nt 10 7 X 10.7.X [1.17.10.X] null + No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 282 JY8QFUQ01C47CW No results 283 JY8QFUQ01AR7AS No results 284 JY8QFUQ01C1HDQ No results 285 JY8QFUQ01C6OZG No results 286 JY8QFUQ01A7RVP No results 287 JY8QFUQ01DLTX0 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 211 97.73 43/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccccca 288 JY8QFUQ01BXUAZ No results 289 JY8QFUQ01AWANM No results 290 JY8QFUQ01BAYFL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.06 201/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaact 291 JY8QFUQ01AB9J6 No results 292 JY8QFUQ01B3J0Z No results 293 JY8QFUQ01B452T No results 294 JY8QFUQ01AM7B2 No results 295 JY8QFUQ01BOC5Y No results 296 JY8QFUQ01DCO0T No results 297 JY8QFUQ01ARPT9 No results 298 JY8QFUQ01BTB20 No results 299 JY8QFUQ01A65TQ No results 300 JY8QFUQ01CF5J0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 117 60.49 49/81 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 301 JY8QFUQ01BOL3F No results 302 JY8QFUQ01CZJHH No results 303 JY8QFUQ01A885O No results 304 JY8QFUQ01BJQ8R unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 466 71.13 138/194 nt 70.62 137/194 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BJQ8R ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgagggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 305 JY8QFUQ01DM3J7 No results 306 JY8QFUQ01BQJMM No results 307 JY8QFUQ01AUM5I No results 308 JY8QFUQ01DQNQS No results 309 JY8QFUQ01CIIWH No results 310 JY8QFUQ01C4XTE No results 311 JY8QFUQ01DTPYG No results 312 JY8QFUQ01AP5CO No results 313 JY8QFUQ01AI1VB unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 110 53.24 74/139 nt 10 7 X 10.7.X [1.17.10.X] null + No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 314 JY8QFUQ01ASZ6N No results 315 JY8QFUQ01BN97P unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV1-18*04 F or Homsap IGHV1-2*01 F or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-24*01 F or Homsap IGHV1-3*01 F or Homsap IGHV1-3*02 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*02 F 61 92.86 13/14 nt X X X X.X.X [4.X.X.X] null + No rearrangement found gggaagaagcctgg 316 JY8QFUQ01C1J78 No results 317 JY8QFUQ01BW4EH No results 318 JY8QFUQ01C3NX6 No results 319 JY8QFUQ01DKFWF No results 320 JY8QFUQ01AE4WV No results 321 JY8QFUQ01C2JYZ No results 322 JY8QFUQ01C7IX0 No results 323 JY8QFUQ01DOGI5 No results 324 JY8QFUQ01B9NL7 No results 325 JY8QFUQ01DM71E unknown (see comment) Homsap IGHV3-72*01 F 110 53.85 70/130 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 326 JY8QFUQ01BJTSM No results 327 JY8QFUQ01DQW5Y No results 328 JY8QFUQ01DK75G No results 329 JY8QFUQ01BM2U2 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 330 JY8QFUQ01B3A93 unknown (see comment) Homsap IGHV1-2*02 F 491 87.4 111/127 nt 86.61 110/127 nt 7 8 X 7.8.X [0.17.9.X] null + No rearrangement found in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) tggatacatttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg 331 JY8QFUQ01B07TW unknown (see comment) Homsap IGHV1-58*01 F, or Homsap IGHV1-58*02 F or Homsap IGHV3-11*01 F or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F 50 100.0 10/10 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found tctggattca 332 JY8QFUQ01A6ZXF unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 137 56.15 73/130 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccaggcttcttccca 333 JY8QFUQ01DJ553 No results 334 JY8QFUQ01BLY2C No results 335 JY8QFUQ01CDHQA No results 336 JY8QFUQ01ALDHU No results 337 JY8QFUQ01AV95H No results 338 JY8QFUQ01DD7UW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 449 67.91 146/215 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (67,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactcag 339 JY8QFUQ01DP56C No results 340 JY8QFUQ01DTAAY No results 341 JY8QFUQ01DPMM7 No results 342 JY8QFUQ01BETAF No results 343 JY8QFUQ01B3JPA No results 344 JY8QFUQ01B6YWG productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD6-13*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARETPKAAANSYSSYVMDVW in-frame + tctctggtggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggactggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctccctgaagctgacctccgtgaccgccgcagacacggccgtgtattactgtgcgagagaaacgcccaaggcagcagctaactcctacagctcttacgttatggacgtctggggccaagggaccacggtcaccgtcttctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 345 JY8QFUQ01DFHWB No results 346 JY8QFUQ01CVSSE No results 347 JY8QFUQ01BP11J No results 348 JY8QFUQ01BO0AK unknown (see comment) Homsap IGHV1-8*01 F (see comment) 399 65.42 140/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (65,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggaaacaccttcaccacttatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggctgaaccctgacagtggtcacacaggctatgcacagaacttccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 349 JY8QFUQ01CXJI9 No results 350 JY8QFUQ01CMCF8 No results 351 JY8QFUQ01AZUKR No results 352 JY8QFUQ01CCVRD No results 353 JY8QFUQ01BUTJV No results 354 JY8QFUQ01BGV3T No results 355 JY8QFUQ01BVPUR unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 125 85.29 29/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctggatttaccttcagtaagttctggatgcatt 356 JY8QFUQ01AQQH4 No results 357 JY8QFUQ01CU1YS unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 358 JY8QFUQ01C6R1U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 140 78.26 36/46 nt 8 X X 8.X.X [1.6.X.X] null + No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgccag 359 JY8QFUQ01AFNDO No results 360 JY8QFUQ01DEJ4T No results 361 JY8QFUQ01BWHN8 No results 362 JY8QFUQ01CVRGF No results 363 JY8QFUQ01BR7JT No results 364 JY8QFUQ01DBTU5 No results 365 JY8QFUQ01DSRBO No results 366 JY8QFUQ01CRWD6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 367 JY8QFUQ01DNZXT No results 368 JY8QFUQ01DSPSC No results 369 JY8QFUQ01DPHDA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 393 87.25 89/102 nt 86.27 88/102 nt 8 8 X 8.8.X [1.15.1.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 4 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 370 JY8QFUQ01CJKQL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 126 61.73 50/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttcccgcacagtcgacggtgtcgtggaactcag 371 JY8QFUQ01DCG2T No results 372 JY8QFUQ01DFQEL No results 373 JY8QFUQ01AEV0H No results 374 JY8QFUQ01ATH3X No results 375 JY8QFUQ01A1BVY No results 376 JY8QFUQ01DLH6V productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 839 86.88 192/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'N' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'T' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); tctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgNaccgccacagacTacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttcccccaa 377 JY8QFUQ01CGDOB unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 734 91.86 158/172 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctg 378 JY8QFUQ01A0FTA No results 379 JY8QFUQ01BMCKP No results 380 JY8QFUQ01C32OL No results 381 JY8QFUQ01B4FU0 No results 382 JY8QFUQ01AY1UT No results 383 JY8QFUQ01DKHE4 No results 384 JY8QFUQ01AQJ6V No results 385 JY8QFUQ01B6N8I No results 386 JY8QFUQ01C3M6T No results 387 JY8QFUQ01DSQVV No results 388 JY8QFUQ01BWXFY No results 389 JY8QFUQ01BR779 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 471 94.29 99/105 nt 93.33 98/105 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggagtagtactgacatatac 390 JY8QFUQ01COY2I No results 391 JY8QFUQ01B40WG No results 392 JY8QFUQ01BOBET No results 393 JY8QFUQ01CTE40 No results 394 JY8QFUQ01A7BCP unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 138 59.05 62/105 nt 58.1 61/105 nt 8 8 X 8.8.X [0.16.2.X] null + No rearrangement found in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cggttacattgttaccacctctggtttcagctgggtgcgacaggccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 395 JY8QFUQ01BHLHM No results 396 JY8QFUQ01DFGLR No results 397 JY8QFUQ01CRSMP No results 398 JY8QFUQ01DDODG No results 399 JY8QFUQ01C51RG unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 619 93.57 131/140 nt 92.86 130/140 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaagggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctc 400 JY8QFUQ01AWT70 No results 401 JY8QFUQ01DUGND No results 402 JY8QFUQ01C3JFU unknown (see comment) Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F 83 51.54 67/130 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons tctggattcacctttggtgactatgctatgagctggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 403 JY8QFUQ01CQPF4 No results 404 JY8QFUQ01A9YCZ No results 405 JY8QFUQ01CLOT5 No results 406 JY8QFUQ01BC7U7 No results 407 JY8QFUQ01AV157 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 408 JY8QFUQ01B3JEK No results 409 JY8QFUQ01DKG75 No results 410 JY8QFUQ01AU5WK unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 467 70.92 139/196 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AU5WK ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 411 JY8QFUQ01DKO1R No results 412 JY8QFUQ01BOWEY No results 413 JY8QFUQ01CANUV No results 414 JY8QFUQ01BJQRL No results 415 JY8QFUQ01AOX45 No results 416 JY8QFUQ01DC5ET No results 417 JY8QFUQ01ALY4Y productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-74*03 F (see comment) 393 78.46 102/130 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 X 5 17 X.5.17 [X.X.38.11] CVRDSGPSGYARYESMDVW in-frame - Low V-REGION identity (78,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagcctcacttcctatggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagtggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 418 JY8QFUQ01BBG0R No results 419 JY8QFUQ01C7G3C No results 420 JY8QFUQ01BEF8K No results 421 JY8QFUQ01BZX6I No results 422 JY8QFUQ01AZT9Z No results 423 JY8QFUQ01DJFJY No results 424 JY8QFUQ01AS5E1 No results 425 JY8QFUQ01A0QZV No results 426 JY8QFUQ01CQ9D6 No results 427 JY8QFUQ01BO8OD No results 428 JY8QFUQ01AFYA4 No results 429 JY8QFUQ01C1COE No results 430 JY8QFUQ01CXQPM No results 431 JY8QFUQ01DI9W4 No results 432 JY8QFUQ01CBZYI No results 433 JY8QFUQ01ANUSS No results 434 JY8QFUQ01BIKF1 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 652 89.51 145/162 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 X 7 11 X.7.11 [X.9.38.11] CVRHVRRFWFDPW in-frame - gagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 435 JY8QFUQ01CB5IP No results 436 JY8QFUQ01DLQOW No results 437 JY8QFUQ01CNVJN No results 438 JY8QFUQ01C3CZA No results 439 JY8QFUQ01DFRDQ No results 440 JY8QFUQ01AJKX6 No results 441 JY8QFUQ01DPZ2N No results 442 JY8QFUQ01A5M7E unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F (see comment) 241 66.39 81/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (66,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 443 JY8QFUQ01CE24H No results 444 JY8QFUQ01AIQ17 unknown (see comment) Homsap IGHV3-22*01 P, or Homsap IGHV3-22*02 P 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tgtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 445 JY8QFUQ01DK0QG No results 446 JY8QFUQ01BICC7 No results 447 JY8QFUQ01DQL67 No results 448 JY8QFUQ01BLB0P No results 449 JY8QFUQ01AN7ZY No results 450 JY8QFUQ01ARZSW No results 451 JY8QFUQ01A2N5I No results 452 JY8QFUQ01B8MWX No results 453 JY8QFUQ01A52H0 No results 454 JY8QFUQ01A24OC No results 455 JY8QFUQ01AZ6K0 No results 456 JY8QFUQ01CB16J No results 457 JY8QFUQ01AFUHA No results 458 JY8QFUQ01AQKLG No results 459 JY8QFUQ01AS1NJ No results 460 JY8QFUQ01AIIG0 No results 461 JY8QFUQ01DACF9 No results 462 JY8QFUQ01A1SWD No results 463 JY8QFUQ01B0WIV No results 464 JY8QFUQ01BA9X0 No results 465 JY8QFUQ01DN8SU No results 466 JY8QFUQ01AXCPB No results 467 JY8QFUQ01CUANZ No results 468 JY8QFUQ01BB6WW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 993 96.26 206/214 nt 95.33 204/214 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDNYGDY## out-of-frame + in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 469 JY8QFUQ01AG3W3 No results 470 JY8QFUQ01CPQER No results 471 JY8QFUQ01DTN1Y No results 472 JY8QFUQ01CY9NS No results 473 JY8QFUQ01DMY4I No results 474 JY8QFUQ01AJ09H No results 475 JY8QFUQ01BTYQ8 No results 476 JY8QFUQ01A408Y unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 477 JY8QFUQ01CFSDN No results 478 JY8QFUQ01C52OU No results 479 JY8QFUQ01CKAWP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 487 83.94 115/137 nt 83.21 114/137 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca 480 JY8QFUQ01C9S8B unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 481 JY8QFUQ01C58WN unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 120 54.55 72/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 482 JY8QFUQ01DC64J unknown (see comment) Homsap IGHV3-11*01 F 882 89.86 195/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcactttcagtgactactacatgaattgggtccgccaggctccagggaagggcctggagtggctttcatacattactgcaagtggtgccatcatacactatgcagactctgtgaagggccgattcatcatctccagggacaacgccaagaactcactgtctctgcagatgaacagcctgagagccgacgacacggccgtctattattgtgctcgggggcaagggcaagggtggaactacctactaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 483 JY8QFUQ01DKRA1 unknown (see comment) Homsap IGHV4-31*06 F, or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*04 F 127 57.27 63/110 nt 10 7 X 10.7.X [1.17.1.X] null + No rearrangement found tctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 484 JY8QFUQ01A8ZYB No results 485 JY8QFUQ01DTNPF No results 486 JY8QFUQ01DRP22 No results 487 JY8QFUQ01AR674 No results 488 JY8QFUQ01DRSSU unknown (see comment) Homsap IGHV3-13*01 F (see comment) 355 67.65 115/170 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found stop codons Low V-REGION identity (67,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 489 JY8QFUQ01A72LA No results 490 JY8QFUQ01B9MV2 No results 491 JY8QFUQ01A8NUS No results 492 JY8QFUQ01ADSW9 No results 493 JY8QFUQ01DNO6S No results 494 JY8QFUQ01A77TK No results 495 JY8QFUQ01CJ228 No results 496 JY8QFUQ01AXNH6 No results 497 JY8QFUQ01AOMWB No results 498 JY8QFUQ01DTX5J productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 499 JY8QFUQ01ARHLG No results 500 JY8QFUQ01B476I No results 501 JY8QFUQ01DVKJP No results 502 JY8QFUQ01BYZ76 No results 503 JY8QFUQ01CYVVQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 822 87.38 187/214 nt 85.98 184/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKSVSSGWPIDEIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggcgtgGAgagtggtcatcagGccattagtggcagtggtagtcggacatattacgcagactccgtgaagggccggttcaccatctccagagacaagtccaagaaaacgttgtatctacaaatgaacagcctgagagccgaggacacggccactttctattgtgcgaagagtgtgagtagtggctggccgatcgacgaaattgactactggggccaggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 504 JY8QFUQ01DT7FQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'GTC' (3 nucleotides at position 71 to 73 in the user submitted sequence), (do not cause frameshift); tctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggGTCagtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 505 JY8QFUQ01CWTEG No results 506 JY8QFUQ01C47A0 No results 507 JY8QFUQ01C2J7E No results 508 JY8QFUQ01C8OKN No results 509 JY8QFUQ01AG2Q1 No results 510 JY8QFUQ01DRK4R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 170 58.65 78/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found tctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 511 JY8QFUQ01BL9TA No results 512 JY8QFUQ01CGZ96 No results 513 JY8QFUQ01BP11C unknown (see comment) Homsap IGHV3-72*01 F 119 54.62 71/130 nt 8 10 X 8.10.X [1.17.6.X] null + No rearrangement found stop codons cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 514 JY8QFUQ01BGOMP No results 515 JY8QFUQ01BMQFZ No results 516 JY8QFUQ01AE8A1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 399 78.03 103/132 nt 75.76 100/132 nt 7 6 X 7.6.X [1.17.12.X] null + No rearrangement found Low V-REGION identity (78,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagctttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 517 JY8QFUQ01DHU4L unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag 518 JY8QFUQ01DVQHF productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccta 519 JY8QFUQ01B65WE No results 520 JY8QFUQ01CXB1G No results 521 JY8QFUQ01BT6J3 No results 522 JY8QFUQ01CUUV5 No results 523 JY8QFUQ01DIF3I No results 524 JY8QFUQ01AFA56 No results 525 JY8QFUQ01CNA11 No results 526 JY8QFUQ01CSIVD No results 527 JY8QFUQ01CX5A6 No results 528 JY8QFUQ01BKEXQ No results 529 JY8QFUQ01AMJT2 No results 530 JY8QFUQ01C68TM No results 531 JY8QFUQ01BAOHD No results 532 JY8QFUQ01BRAT9 No results 533 JY8QFUQ01AKP6C unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + stop codons ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttagcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagcccctaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 534 JY8QFUQ01A8HRS No results 535 JY8QFUQ01BKB83 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 237 60.12 101/168 nt 8 8 X 8.8.X [0.17.22.X] null + No rearrangement found Low V-REGION identity (60,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 536 JY8QFUQ01A4KPV unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 84 83.33 20/24 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tctggattcagcgtcaacaacaac 537 JY8QFUQ01DE2KK unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 199 78.46 51/65 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found tctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccccc 538 JY8QFUQ01BGWW0 No results 539 JY8QFUQ01BALYU No results 540 JY8QFUQ01B3BH7 No results 541 JY8QFUQ01B2I04 No results 542 JY8QFUQ01CXHCH No results 543 JY8QFUQ01AD6ZM No results 544 JY8QFUQ01AZMNG No results 545 JY8QFUQ01A4K11 No results 546 JY8QFUQ01DQ3IY productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + tctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 547 JY8QFUQ01DQUSE productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt 8 10 7 8.10.7 [0.16.38.11] CTARNFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ctggactcactttcaataacgcctggttgaactgggtccgccaggctccagggaagggactggagtggttggccatattaaacccgaggctgatggtgggacaacagactacaatgcacccgtgaaaggcagattcaccatctcaagagatgtttcagcaaacacgctgtatctgcaaatgaacagcctgaaaaccgaagacacagccgtctattactgtaccgcaagaaactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 548 JY8QFUQ01CU1FT No results 549 JY8QFUQ01CVRCR No results 550 JY8QFUQ01BSAFV No results 551 JY8QFUQ01DN9PB productive Homsap IGHV4-61*03 F 152 66.25 53/80 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 X X 13 X.X.13 [X.X.26.11] CATVRHLGERIFDFW in-frame + tctctggggccaccatgagtagtttctactggagctggctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 552 JY8QFUQ01A01FG No results 553 JY8QFUQ01BG9CW No results 554 JY8QFUQ01C9E33 No results 555 JY8QFUQ01C16F0 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 135 77.78 35/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgcca 556 JY8QFUQ01ALN7Q No results 557 JY8QFUQ01DEYBF No results 558 JY8QFUQ01ANDSC No results 559 JY8QFUQ01CTY7U unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 560 JY8QFUQ01AMU1R unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 561 JY8QFUQ01CU2L0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 161 57.89 77/133 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 562 JY8QFUQ01DOXZT No results 563 JY8QFUQ01CSG56 No results 564 JY8QFUQ01AIB60 No results 565 JY8QFUQ01CP7Q3 No results 566 JY8QFUQ01B48ZH No results 567 JY8QFUQ01DRKWV No results 568 JY8QFUQ01DQ4YE No results 569 JY8QFUQ01CVXN6 No results 570 JY8QFUQ01A56PJ No results 571 JY8QFUQ01BEZLP No results 572 JY8QFUQ01DO88X unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [1.17.38.11] CARAPGWMNPFDF## out-of-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggccactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 573 JY8QFUQ01BFHP5 No results 574 JY8QFUQ01CM61C No results 575 JY8QFUQ01A23JI No results 576 JY8QFUQ01DUGFP No results 577 JY8QFUQ01BLTM8 No results 578 JY8QFUQ01AHNAT No results 579 JY8QFUQ01ASTJ6 No results 580 JY8QFUQ01B1ZDH No results 581 JY8QFUQ01A6IGF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.37.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggagGtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 582 JY8QFUQ01AS1KI No results 583 JY8QFUQ01AI3IO No results 584 JY8QFUQ01C2SB7 No results 585 JY8QFUQ01AEO3Z No results 586 JY8QFUQ01B5XEH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 677 95.3 142/149 nt 94.63 141/149 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 1 8 8.1.8 [1.1.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01B5XEH ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 68 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 587 JY8QFUQ01DOON7 No results 588 JY8QFUQ01AQYNY No results 589 JY8QFUQ01CMHYY No results 590 JY8QFUQ01CWE8D No results 591 JY8QFUQ01BO5WL No results 592 JY8QFUQ01AIZZR No results 593 JY8QFUQ01C9ZRF No results 594 JY8QFUQ01DE8IY No results 595 JY8QFUQ01AVNLI unknown (see comment) Homsap IGHV3-11*01 F (see comment) 618 76.78 162/211 nt 8 7 X 8.7.X [0.17.38.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AVNLI ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 596 JY8QFUQ01C2VVV No results 597 JY8QFUQ01B9Z61 No results 598 JY8QFUQ01ACK6B No results 599 JY8QFUQ01DLUGR No results 600 JY8QFUQ01DS5HR No results 601 JY8QFUQ01DRGVP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [0.17.38.11] CAREVTRLTVPYYLYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); cggattcacctttagtagttactggatgcactgggtccgccAaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagcctgagagccggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 602 JY8QFUQ01AHMRK No results 603 JY8QFUQ01AS4U6 No results 604 JY8QFUQ01DNYZ7 No results 605 JY8QFUQ01B7I0E No results 606 JY8QFUQ01C745G No results 607 JY8QFUQ01C7EWY No results 608 JY8QFUQ01C3IZ7 No results 609 JY8QFUQ01CR0HB No results 610 JY8QFUQ01CJ4IC No results 611 JY8QFUQ01BOBV7 No results 612 JY8QFUQ01BL2KM No results 613 JY8QFUQ01DKFYD No results 614 JY8QFUQ01CPNL9 No results 615 JY8QFUQ01A6WTE No results 616 JY8QFUQ01AMNJH No results 617 JY8QFUQ01BAUWF No results 618 JY8QFUQ01A6T2J No results 619 JY8QFUQ01AJ0OS No results 620 JY8QFUQ01BKBGF No results 621 JY8QFUQ01DB108 No results 622 JY8QFUQ01B7YYU No results 623 JY8QFUQ01BBASZ No results 624 JY8QFUQ01BQWDF No results 625 JY8QFUQ01AO955 No results 626 JY8QFUQ01AHDUP No results 627 JY8QFUQ01CSEK4 No results 628 JY8QFUQ01C2E4Q No results 629 JY8QFUQ01A0CIX No results 630 JY8QFUQ01B1FJP No results 631 JY8QFUQ01A46LO No results 632 JY8QFUQ01ASMJE productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); tctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 633 JY8QFUQ01DOJG4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 701 80.47 173/215 nt 80.0 172/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca 634 JY8QFUQ01DI7CS unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 420 76.19 112/147 nt 8 7 X 8.7.X [1.17.15.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DI7CS ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtctgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactc 635 JY8QFUQ01BN181 No results 636 JY8QFUQ01DJYKG No results 637 JY8QFUQ01B28X1 No results 638 JY8QFUQ01AS1KQ No results 639 JY8QFUQ01CZDB6 No results 640 JY8QFUQ01CIKOL No results 641 JY8QFUQ01BUDPR unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 642 JY8QFUQ01DBTI3 unknown (see comment) Homsap IGHV3-74*03 F 108 50.79 96/189 nt 8 8 X 8.8.X [1.17.28.X] null + No rearrangement found stop codons ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 643 JY8QFUQ01CVVLT No results 644 JY8QFUQ01DP6R4 No results 645 JY8QFUQ01C8AIG No results 646 JY8QFUQ01A6HYZ unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 106 59.74 46/77 nt 58.44 45/77 nt 7 X X 7.X.X [1.17.X.X] null + No rearrangement found in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctggattcacgttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 647 JY8QFUQ01BAHEK No results 648 JY8QFUQ01DV2ZV No results 649 JY8QFUQ01C6PBL No results 650 JY8QFUQ01B5TWP No results 651 JY8QFUQ01AQLGT No results 652 JY8QFUQ01BBQ0C No results 653 JY8QFUQ01A82YB No results 654 JY8QFUQ01CT128 No results 655 JY8QFUQ01ANLP4 No results 656 JY8QFUQ01DJ71O No results 657 JY8QFUQ01DAI4Z No results 658 JY8QFUQ01A698F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc 659 JY8QFUQ01AH6JY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 805 86.11 186/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDS## out-of-frame + tctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctggggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 660 JY8QFUQ01DSHN9 No results 661 JY8QFUQ01CVWH1 No results 662 JY8QFUQ01A9PO9 No results 663 JY8QFUQ01AU9D7 No results 664 JY8QFUQ01DA2A8 No results 665 JY8QFUQ01CSODU No results 666 JY8QFUQ01CMCU9 No results 667 JY8QFUQ01DU4DT No results 668 JY8QFUQ01CS1QJ No results 669 JY8QFUQ01DTA61 No results 670 JY8QFUQ01DAXBN No results 671 JY8QFUQ01CY465 No results 672 JY8QFUQ01B154Q productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 853 87.39 194/222 nt 86.94 193/222 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.37.11] CTWDSTGYFRLTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 80 of V-REGION: 1 nucleotides (from position 150 in the user submitted sequence), (cause frameshift) ctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 673 JY8QFUQ01BLGF2 No results 674 JY8QFUQ01BOMJ1 productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaacgataggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 675 JY8QFUQ01DR1HV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKYVEGWSYTGGLL##SYAMDVW out-of-frame + in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'AC' (2 nucleotides at position 117 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'TC' (2 nucleotides at position 157 to 158 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggaggggcgtggaAgtgggtctAcaggtctcagtggtagtggtgatagcacatactactcaaaACctccgtgaagggccggttcatcatcttcagagacaattTCcaaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggcctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactca 676 JY8QFUQ01DW425 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 180 53.7 116/216 nt 8 8 X 8.8.X [1.17.37.X] null + No rearrangement found gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 677 JY8QFUQ01CWGVS No results 678 JY8QFUQ01COA86 No results 679 JY8QFUQ01BLQBF No results 680 JY8QFUQ01DD2I0 No results 681 JY8QFUQ01CVQ5V productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 682 JY8QFUQ01CEUZZ No results 683 JY8QFUQ01CM1RQ No results 684 JY8QFUQ01C3RZV unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 685 JY8QFUQ01C1MVU No results 686 JY8QFUQ01CWP9S No results 687 JY8QFUQ01CJ7U8 No results 688 JY8QFUQ01C74EW unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgaaccggtgacggtgtcgtggaactcag 689 JY8QFUQ01CV1KZ No results 690 JY8QFUQ01DOW2U No results 691 JY8QFUQ01DFFIC No results 692 JY8QFUQ01A9SLL No results 693 JY8QFUQ01C7H18 productive (see comment) Homsap IGHV3-7*01 F 895 90.74 196/216 nt 89.35 193/216 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARGTSVDPGIDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'C' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tctggattcacctttagtaattattggatgcactgggtccgccaggtttcagggaggggCgctggagtgcgtggccaccataaacgaagatggaagtgaGgagacactatgtggacCtctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 694 JY8QFUQ01DI6GR No results 695 JY8QFUQ01AQS6J No results 696 JY8QFUQ01CW9LP No results 697 JY8QFUQ01DTOEH unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 348 86.02 80/93 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found tctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 698 JY8QFUQ01CDT9Z No results 699 JY8QFUQ01B98W0 No results 700 JY8QFUQ01BJQT2 No results 701 JY8QFUQ01ADSZU No results 702 JY8QFUQ01CJAZY No results 703 JY8QFUQ01A0EHO No results 704 JY8QFUQ01DNR43 unknown (see comment) Homsap IGHV3-7*02 F (see comment) 232 57.73 112/194 nt 57.22 111/194 nt 8 8 X 8.8.X [1.16.31.X] null + No rearrangement found stop codons Low V-REGION identity (57,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaagggctggagtgggtggccaacataatgccagatggagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 705 JY8QFUQ01CMW7Z No results 706 JY8QFUQ01CFB7L No results 707 JY8QFUQ01CE97L unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 109 60.81 45/74 nt 59.46 44/74 nt 7 X X 7.X.X [0.16.X.X] null + No rearrangement found in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctggattcacgttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccaggcttcttcccca 708 JY8QFUQ01A8IAU No results 709 JY8QFUQ01DQ5TX No results 710 JY8QFUQ01CXXJ4 No results 711 JY8QFUQ01DXEL1 No results 712 JY8QFUQ01A9YYE unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F (see comment) 212 81.25 52/64 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (81,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccc 713 JY8QFUQ01AM6FE No results 714 JY8QFUQ01AIR6K No results 715 JY8QFUQ01AO1H5 No results 716 JY8QFUQ01BXGUS No results 717 JY8QFUQ01BF84M No results 718 JY8QFUQ01C5HO3 No results 719 JY8QFUQ01BG2IK No results 720 JY8QFUQ01CF2BM unknown (see comment) Homsap IGHV3-7*03 F (see comment) 706 80.56 174/216 nt 80.09 173/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttaataactattggatgacatgggtccgccaggctccagggaagggctggagttggtggccaacataaagcaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 721 JY8QFUQ01CUHH5 unknown (see comment) Homsap IGHV3-66*02 F 743 92.44 159/172 nt 91.86 158/172 nt 8 7 X 8.7.X [4.16.21.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta 722 JY8QFUQ01DDJCP No results 723 JY8QFUQ01BCVWS No results 724 JY8QFUQ01DK9N6 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 638 94.41 135/143 nt 93.01 133/143 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-16*01 F 3 7 X X 7.X.X [1.8.30.11] CARRDVGLH#FDLW out-of-frame + in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 53 in the user submitted sequence), (do not cause frameshift) tctggatccaatttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgctttgatctgtggggccaggggacaatggtcagcgtctcttcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 725 JY8QFUQ01DVXK9 No results 726 JY8QFUQ01CZDNQ No results 727 JY8QFUQ01CZFR8 No results 728 JY8QFUQ01C8TM1 No results 729 JY8QFUQ01DGT7R No results 730 JY8QFUQ01BAPJQ No results 731 JY8QFUQ01BZK37 No results 732 JY8QFUQ01BE8EU No results 733 JY8QFUQ01BJ1X4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 734 JY8QFUQ01A91H2 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 735 JY8QFUQ01B7U2A No results 736 JY8QFUQ01DAT0N No results 737 JY8QFUQ01DR2ZT productive (see comment) Homsap IGHV1-2*02 F (see comment) 777 84.58 181/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGLSYDSSPYWGYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tggatacatcttcaatgacttctacatatattgggtgcgacaGggcccctggacaagGggcttgagtggatgggatggttcaaccctaatagtcgtgtcacagactatgcagagaaatttcagggcagggtcaccatgaccggggacccgtcccgcagcacagtccacctgaaactgacccgcctgaagtcggacgacacggccgtctattactgcgcgagaggtctctcctatgacagtagtccttattggggctactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 738 JY8QFUQ01C2RD7 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 739 JY8QFUQ01BBT7W No results 740 JY8QFUQ01ARSEU No results 741 JY8QFUQ01B3E3Q No results 742 JY8QFUQ01AJBL2 No results 743 JY8QFUQ01BG4HV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1012 96.76 209/216 nt 96.3 208/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.16.38.11] CAKSLYNSSPYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacaactatgccatgaactgggtccgccaggctccagggaagggctggagtgggtctcatctattagtggtagtattagtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagagcttatataacagcagcccctactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggccccatcggtcttcccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 744 JY8QFUQ01BZSLD No results 745 JY8QFUQ01BY3XK No results 746 JY8QFUQ01DW1LD No results 747 JY8QFUQ01A46E5 No results 748 JY8QFUQ01DAQTU No results 749 JY8QFUQ01CPRYN No results 750 JY8QFUQ01CUKXW No results 751 JY8QFUQ01C23RC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggcctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag 752 JY8QFUQ01C5MT6 No results 753 JY8QFUQ01BCER9 No results 754 JY8QFUQ01BJ9FO No results 755 JY8QFUQ01AZDYV No results 756 JY8QFUQ01C8T1H No results 757 JY8QFUQ01DL1WJ No results 758 JY8QFUQ01CA1LA No results 759 JY8QFUQ01DVPSG unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 266 57.8 126/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (57,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 760 JY8QFUQ01CR15T No results 761 JY8QFUQ01B51MO No results 762 JY8QFUQ01CLAUP No results 763 JY8QFUQ01BECNO No results 764 JY8QFUQ01B4THL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 487 89.92 107/119 nt 88.24 105/119 nt 8 8 X 8.8.X [1.17.5.X] null - No rearrangement found in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); cctctggaGTtcagccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtCagtagtgacatatactacgcagaccca 765 JY8QFUQ01BUAXD No results 766 JY8QFUQ01CJS8T No results 767 JY8QFUQ01C24AK No results 768 JY8QFUQ01ATJUK No results 769 JY8QFUQ01DCOU8 No results 770 JY8QFUQ01BEP2R No results 771 JY8QFUQ01C0COZ No results 772 JY8QFUQ01BM1D1 No results 773 JY8QFUQ01CDNFM No results 774 JY8QFUQ01BU5NL productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 201 86.54 45/52 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAAVGVGSAVSFQYW in-frame + ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttattacggtggaaccacatattacgctgactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctnagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 775 JY8QFUQ01DHHI6 No results 776 JY8QFUQ01BU7OF No results 777 JY8QFUQ01A6ZWI productive Homsap IGHV3-21*04 F 483 89.26 108/121 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 X 2 10 X.2.10 [X.X.38.11] CARAVSNQVDVW in-frame - ctctggattcgccttcaactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccaggcgttcttccccca 778 JY8QFUQ01A6Q2P No results 779 JY8QFUQ01CGWP9 unknown (see comment) Homsap IGHV3-48*02 F 895 90.28 195/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 780 JY8QFUQ01DHZ6E No results 781 JY8QFUQ01B9W2W No results 782 JY8QFUQ01BNHH9 No results 783 JY8QFUQ01CM6DN unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 559 78.57 143/182 nt 8 8 X 8.8.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtggaactcag 784 JY8QFUQ01DEPC1 No results 785 JY8QFUQ01CHUDH No results 786 JY8QFUQ01AGUL6 No results 787 JY8QFUQ01A85PF No results 788 JY8QFUQ01BUK3U No results 789 JY8QFUQ01BREWM No results 790 JY8QFUQ01C664S productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.37.11] CTHLREEMSYEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 791 JY8QFUQ01A6Y9U unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 792 JY8QFUQ01DSWAV No results 793 JY8QFUQ01DVBVI No results 794 JY8QFUQ01CDWXY No results 795 JY8QFUQ01BEZNM unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*05 F 597 94.7 125/132 nt 8 8 X 8.8.X [0.17.10.X] null + No rearrangement found tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcac 796 JY8QFUQ01BGZ27 No results 797 JY8QFUQ01DVSPM No results 798 JY8QFUQ01DBYSE No results 799 JY8QFUQ01BV7PO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 800 JY8QFUQ01DV0AR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 938 91.86 203/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASDLGGQKSYW in-frame - cagcctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 801 JY8QFUQ01B9V81 No results 802 JY8QFUQ01C3S4F No results 803 JY8QFUQ01AZ3CP No results 804 JY8QFUQ01DUGYW No results 805 JY8QFUQ01AT8P8 No results 806 JY8QFUQ01DU4WR No results 807 JY8QFUQ01C8EOC No results 808 JY8QFUQ01CDEJP No results 809 JY8QFUQ01A4K8H No results 810 JY8QFUQ01DWME3 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 811 JY8QFUQ01A4GQ1 No results 812 JY8QFUQ01DJIGF No results 813 JY8QFUQ01C2YDZ No results 814 JY8QFUQ01BLWTN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 87.61 191/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 815 JY8QFUQ01CJA85 No results 816 JY8QFUQ01AK99H No results 817 JY8QFUQ01AYY6J No results 818 JY8QFUQ01DAHAR No results 819 JY8QFUQ01C0TX2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 820 JY8QFUQ01BDZZ6 No results 821 JY8QFUQ01AHM5M No results 822 JY8QFUQ01DTVIZ No results 823 JY8QFUQ01DBUHS unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 824 JY8QFUQ01DFSIO No results 825 JY8QFUQ01B6DKH No results 826 JY8QFUQ01B2GPJ No results 827 JY8QFUQ01A4NJN No results 828 JY8QFUQ01BIILY No results 829 JY8QFUQ01DQURD No results 830 JY8QFUQ01DTIAX No results 831 JY8QFUQ01BD2DM No results 832 JY8QFUQ01BFWOX No results 833 JY8QFUQ01BGN4A No results 834 JY8QFUQ01CSDSK No results 835 JY8QFUQ01C20Y3 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 102 53.03 70/132 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 836 JY8QFUQ01B4MJJ No results 837 JY8QFUQ01DDOJR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 838 JY8QFUQ01DEXOG No results 839 JY8QFUQ01BRI4Q unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 270 92.06 58/63 nt 8 X X 8.X.X [1.12.X.X] null - No rearrangement found tctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaagggctgg 840 JY8QFUQ01ANOKI No results 841 JY8QFUQ01DUH2N No results 842 JY8QFUQ01BUA86 No results 843 JY8QFUQ01AE460 No results 844 JY8QFUQ01DQHKE No results 845 JY8QFUQ01A47P0 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 846 JY8QFUQ01AV8WH No results 847 JY8QFUQ01A1PUU No results 848 JY8QFUQ01BTDHW unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 124 54.55 72/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacntggtcatcgcctgcctggtccagggcttcttccccc 849 JY8QFUQ01C8V09 unknown (see comment) Homsap IGHV1-8*01 F 601 95.42 125/131 nt 8 8 X 8.8.X [0.17.10.X] null + No rearrangement found tggatacaccttcaccaattatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaaaattggaaacacaggctctgcgcagaagttccagggcagagtca 850 JY8QFUQ01ASXZF unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 851 JY8QFUQ01DWSB4 No results 852 JY8QFUQ01BF7KJ unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) gagttccacgacaccgtcaccggttcgggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga 853 JY8QFUQ01ALKXU No results 854 JY8QFUQ01B41VG No results 855 JY8QFUQ01CE30D No results 856 JY8QFUQ01CJ6LP No results 857 JY8QFUQ01BL52H unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 858 JY8QFUQ01DPFUD No results 859 JY8QFUQ01BF4SK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 860 JY8QFUQ01BUIHI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 671 78.44 171/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag 861 JY8QFUQ01A8AU3 No results 862 JY8QFUQ01BBWG2 No results 863 JY8QFUQ01BG99N unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 328 71.64 96/134 nt 70.9 95/134 nt 7 8 X 7.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (71,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) cctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaacggtgacggtgtcgtggaactcag 864 JY8QFUQ01CUU12 No results 865 JY8QFUQ01DV41N No results 866 JY8QFUQ01AKQLX No results 867 JY8QFUQ01DOBQP unproductive (see comment) Homsap IGHV4-59*10 F (see comment) 266 57.8 126/218 nt 57.34 125/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [3.17.37.X] null + stop codons no junction found The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DOBQP ; 8 AA in Homsap_IGHV4-59*10), and low V-REGION identity (57,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); tccagtggcattgttaatggcgaaggtttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctagagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggactCctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 868 JY8QFUQ01CKWZR unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 643 77.31 167/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag 869 JY8QFUQ01DTX30 No results 870 JY8QFUQ01A1RCR No results 871 JY8QFUQ01CQ01A No results 872 JY8QFUQ01C5X6U unknown (see comment) Homsap IGHV3-66*03 F (see comment) 480 69.16 148/214 nt 68.69 147/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (69,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'TATGACTT' (8 nucleotides at position 83 to 90 in the user submitted sequence), (cause frameshift); ctctgggctcaccgtcagttacaactatttgacctgggtccgccaggcaccagggaaggggccggagtgagtctcacttattTATGACTTtataactgtggtaatacatactacgcagactccgtgaagggccgattcaccatctccagagacagggttcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 873 JY8QFUQ01DEX2B No results 874 JY8QFUQ01B7PLT No results 875 JY8QFUQ01CDZ1V No results 876 JY8QFUQ01B783U unknown (see comment) Homsap IGHV4-34*04 F, or Homsap IGHV4-34*07 F 102 53.03 70/132 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found gtctggtgagtccttcagtggttactactggagttggatccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 877 JY8QFUQ01CMDBC No results 878 JY8QFUQ01C2Q34 No results 879 JY8QFUQ01COLPI unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 880 JY8QFUQ01DO6FK No results 881 JY8QFUQ01CE65R unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 100 57.83 48/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 882 JY8QFUQ01BV5VD No results 883 JY8QFUQ01B91NW No results 884 JY8QFUQ01DXAE5 No results 885 JY8QFUQ01CJXCD No results 886 JY8QFUQ01DNNHI unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 119 57.28 59/103 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 887 JY8QFUQ01AQBRP No results 888 JY8QFUQ01A5VGI No results 889 JY8QFUQ01C62I8 No results 890 JY8QFUQ01A5MLI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 460 81.75 112/137 nt 81.02 111/137 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (81,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca 891 JY8QFUQ01DVTUN No results 892 JY8QFUQ01DDYI9 No results 893 JY8QFUQ01A0ZHQ No results 894 JY8QFUQ01ACF7S productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + tctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 895 JY8QFUQ01BHB8R No results 896 JY8QFUQ01CTM8X No results 897 JY8QFUQ01BSF5D No results 898 JY8QFUQ01CUDPM No results 899 JY8QFUQ01DUU48 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 895 90.74 196/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + tctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcttcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 900 JY8QFUQ01A9D8P No results 901 JY8QFUQ01CWDUG No results 902 JY8QFUQ01AP21K No results 903 JY8QFUQ01DS3Y4 No results 904 JY8QFUQ01AX9HH No results 905 JY8QFUQ01BK6NF productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*03 F (see comment) 379 80.0 96/120 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 X 2 17 X.2.17 [X.X.38.11] CAKDTITMGGDVAPLFDYW in-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 906 JY8QFUQ01C4K4T No results 907 JY8QFUQ01DG5GN No results 908 JY8QFUQ01AY698 No results 909 JY8QFUQ01B7E47 No results 910 JY8QFUQ01DQIR0 No results 911 JY8QFUQ01DFD3I unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac 912 JY8QFUQ01AZ1G9 No results 913 JY8QFUQ01A9W1A No results 914 JY8QFUQ01DTQ02 productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - gcctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 915 JY8QFUQ01C9DSU No results 916 JY8QFUQ01A7FQQ No results 917 JY8QFUQ01BKVJZ No results 918 JY8QFUQ01CW6SK unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 882 89.86 195/217 nt Homsap IGHJ5*02 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.0] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtcgctatggcatgcactgggtccgccaggctccagggaaggggctggcatgggtttcatacattagtgccagtagcagcaccaagtactacgcaaattctctgaagggccggttcaccatctccagagacaacgccaagaattcactgtatctggaaatcaacagcctgagcgacgaggacacgtctgtgtattactgtgcgcgagatgactacggcttcttccccca 919 JY8QFUQ01AJBY4 No results 920 JY8QFUQ01B2UQO unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 80 80.0 20/25 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tctggattcagcgtcaacaacaaca 921 JY8QFUQ01DCQ3Y No results 922 JY8QFUQ01BNSHZ unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 368 64.39 132/205 nt 63.9 131/205 nt 8 7 X 8.7.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (64,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 923 JY8QFUQ01C31LE No results 924 JY8QFUQ01B19XO No results 925 JY8QFUQ01C2606 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 71.91 128/178 nt 8 8 X 8.8.X [1.16.25.X] null + No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaagggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 926 JY8QFUQ01BEGQ1 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 91 52.34 67/128 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 927 JY8QFUQ01BK3H5 No results 928 JY8QFUQ01CV45O unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 634 77.31 167/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcgacagcaccccacagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 929 JY8QFUQ01BF1LO unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 930 JY8QFUQ01DKYKH unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-9*01 F or Homsap IGHV3-9*03 F 158 71.88 46/64 nt 70.31 45/64 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found in FR2-IMGT at codon 43 of V-REGION: 'CGC' (3 nucleotides at position 41 to 43 in the user submitted sequence), (do not cause frameshift); ctctggattccggtttgatgattatgccatacattgggttCGCctgcctggtccagggcttcttccc 931 JY8QFUQ01A1MA8 No results 932 JY8QFUQ01AJHU4 No results 933 JY8QFUQ01B4M1X No results 934 JY8QFUQ01DTX7W productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.17.38.11] CAGGRGWLIDYW in-frame - gcctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 935 JY8QFUQ01ARIT8 No results 936 JY8QFUQ01CGVGC No results 937 JY8QFUQ01CS4OH No results 938 JY8QFUQ01B6UMA unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 245 58.55 113/193 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (58,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 939 JY8QFUQ01BAZV6 No results 940 JY8QFUQ01AWSFJ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 432 77.78 112/144 nt 8 8 X 8.8.X [1.17.13.X] null + No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccc 941 JY8QFUQ01AG4YS No results 942 JY8QFUQ01DP7OF No results 943 JY8QFUQ01BC5DI unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F (see comment) 300 73.91 85/115 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 X 0 13 X.0.13 [X.X.38.11] CARFSGSYKSAFDIW in-frame - stop codons Low V-REGION identity (73,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgaagatctcctgtaaggggttctggatacatctttaccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 944 JY8QFUQ01BR526 No results 945 JY8QFUQ01CTTTC No results 946 JY8QFUQ01DFECA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 957 94.39 202/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 947 JY8QFUQ01DU75V No results 948 JY8QFUQ01BRZZW No results 949 JY8QFUQ01BVK9J unproductive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAWGSQRR#DYW out-of-frame + ctctggattcaccttcggtaactcaaccatgaactgggtccgccaggctccagggaaggggctggaatggctgtcatatcttagtagtggtggtgatgtcaaatactacgcaggctctctgaagggccgattcaccatctccagagacagtgccaggaactcactgtatctgcaaatgaacagcctgacagacgaggacacggccgtatattactgtgcatgggggtcccaacggcgccgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 950 JY8QFUQ01BBFU0 No results 951 JY8QFUQ01CY5Z7 No results 952 JY8QFUQ01AL68M No results 953 JY8QFUQ01CFFD0 No results 954 JY8QFUQ01B8BOJ No results 955 JY8QFUQ01CCIY9 No results 956 JY8QFUQ01BI1O7 productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggaggggcgtggagtgggtggccaacataaagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 957 JY8QFUQ01B9LUD No results 958 JY8QFUQ01AEXV8 unknown (see comment) Homsap IGHV3-48*01 F (see comment) 482 71.36 142/199 nt 70.85 141/199 nt 8 7 X 8.7.X [1.17.33.X] null - No rearrangement found Low V-REGION identity (71,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 959 JY8QFUQ01AXMV3 No results 960 JY8QFUQ01DM849 No results 961 JY8QFUQ01DR9B3 productive Homsap IGHV3-13*01 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 10 8.7.10 [1.17.38.11] CATISDYRFEFW in-frame - tctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 962 JY8QFUQ01AHAOC No results 963 JY8QFUQ01CI89C No results 964 JY8QFUQ01BL574 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 179 59.4 79/133 nt 8 6 X 8.6.X [2.17.11.X] null - No rearrangement found stop codons cctcctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 965 JY8QFUQ01CXG76 No results 966 JY8QFUQ01BUMP8 unknown (see comment) Homsap IGHV1-3*01 F, or Homsap IGHV1-3*02 F (see comment) 265 63.82 97/152 nt 8 8 X 8.8.X [0.17.17.X] null + No rearrangement found Low V-REGION identity (63,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcaccttcactgactatgctatgcattgggtgcgccaggcccccggacaagggcttgagtggatgggatggatcaacgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 967 JY8QFUQ01B9HSO No results 968 JY8QFUQ01AXNBU No results 969 JY8QFUQ01CH6IV No results 970 JY8QFUQ01C80PM No results 971 JY8QFUQ01C8ML6 No results 972 JY8QFUQ01DTXID No results 973 JY8QFUQ01ATKPL unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 85 51.49 69/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 974 JY8QFUQ01A49XC unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 975 JY8QFUQ01BXXVF No results 976 JY8QFUQ01DACCQ No results 977 JY8QFUQ01DR4Q4 productive Homsap IGHV3-7*01 F (see comment) 778 84.72 183/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 978 JY8QFUQ01CP4TY No results 979 JY8QFUQ01AKR55 No results 980 JY8QFUQ01B1UTN No results 981 JY8QFUQ01BU42Z No results 982 JY8QFUQ01B5CG9 No results 983 JY8QFUQ01B1H6W No results 984 JY8QFUQ01CCGH3 No results 985 JY8QFUQ01BYK6X unknown (see comment) Homsap IGHV4-61*02 F (see comment) 707 80.73 176/218 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 986 JY8QFUQ01CQI4W No results 987 JY8QFUQ01CC9PC No results 988 JY8QFUQ01ASVKR unknown (see comment) Homsap IGHV1-2*02 F 482 86.61 110/127 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagg 989 JY8QFUQ01AJTX9 No results 990 JY8QFUQ01CW1ZW No results 991 JY8QFUQ01BRKI0 productive Homsap IGHV3-11*01 F 110 61.04 47/77 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.25.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcactttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 992 JY8QFUQ01CVEPJ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 616 75.93 164/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccaccaatggatggacgtggtcgtcgcatgcctggtccagggcttct 993 JY8QFUQ01C19QG No results 994 JY8QFUQ01BMH34 No results 995 JY8QFUQ01DJ0DY No results 996 JY8QFUQ01BK19C No results 997 JY8QFUQ01DU3EC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 199 78.46 51/65 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found tctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggcttcttccccc 998 JY8QFUQ01BI2UW No results 999 JY8QFUQ01C40SU No results 1000 JY8QFUQ01AN0PO No results 1001 JY8QFUQ01BTSGB unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1002 JY8QFUQ01BF7X1 No results 1003 JY8QFUQ01A1QF0 No results 1004 JY8QFUQ01DO27W unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 110 60.53 46/76 nt 59.21 45/76 nt 7 X X 7.X.X [1.16.X.X] null + No rearrangement found in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctggattcacgttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 1005 JY8QFUQ01DWMO7 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1006 JY8QFUQ01AOG4M No results 1007 JY8QFUQ01COT7H unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 242 82.86 58/70 nt 8 X X 8.X.X [0.15.X.X] null + No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttccccca 1008 JY8QFUQ01APOXR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 760 83.8 181/216 nt 83.33 180/216 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggtttggcgtgaactaggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1009 JY8QFUQ01DJXIF No results 1010 JY8QFUQ01B62MI No results 1011 JY8QFUQ01A7YQ1 No results 1012 JY8QFUQ01BAM0R productive Homsap IGHV3-21*04 F 958 93.98 203/216 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1013 JY8QFUQ01B3HHR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons tctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 1014 JY8QFUQ01C4XVY No results 1015 JY8QFUQ01CU7WL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 98 52.63 70/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1016 JY8QFUQ01BHJ7K No results 1017 JY8QFUQ01AD3VP unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 246 84.06 58/69 nt 8 X X 8.X.X [0.14.X.X] null - No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttcccca 1018 JY8QFUQ01BL6AV No results 1019 JY8QFUQ01CQE2I unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 120 54.55 72/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1020 JY8QFUQ01C8HC8 productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1021 JY8QFUQ01AIWKD No results 1022 JY8QFUQ01DR3OF unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 467 70.92 139/196 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DR3OF ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1023 JY8QFUQ01BFB9X No results 1024 JY8QFUQ01CRXO0 No results 1025 JY8QFUQ01DG75B No results 1026 JY8QFUQ01CJZ05 No results 1027 JY8QFUQ01AY8M2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 661 78.24 169/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactca 1028 JY8QFUQ01CC772 No results 1029 JY8QFUQ01CVZJH productive Homsap IGHV4-61*02 F (see comment) 749 82.35 182/221 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERGASIGEAGGLDSW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggccccgtcaacaatggtgatcagtattggagctggatccggcagcccgccgggaaggggctggagtggatcggacgtgtttctgctagtgggacctacagctacaatccctccctcaggagtcggatcaccatctcaatagacatgtctaagaatcacttctccctgaggttgatttctgtgacggccgcagacacggccttatattattgtgcgagagagcgtggtgcgtcgattggcgaagcgggaggccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 1030 JY8QFUQ01C62PI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 325 88.1 74/84 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame + accctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggcagcagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact 1031 JY8QFUQ01AO53D No results 1032 JY8QFUQ01CJY9B No results 1033 JY8QFUQ01CJDOK unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 302 59.63 130/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found stop codons Low V-REGION identity (59,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1034 JY8QFUQ01DMYZ4 No results 1035 JY8QFUQ01DR1XF No results 1036 JY8QFUQ01AFH41 No results 1037 JY8QFUQ01CE24O No results 1038 JY8QFUQ01DU0CJ No results 1039 JY8QFUQ01ABQC1 No results 1040 JY8QFUQ01CBNG6 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 288 65.36 100/153 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found Low V-REGION identity (65,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 1041 JY8QFUQ01DKGFO No results 1042 JY8QFUQ01A4GO7 No results 1043 JY8QFUQ01A9IQN No results 1044 JY8QFUQ01BPO33 No results 1045 JY8QFUQ01BM30W No results 1046 JY8QFUQ01DLARJ No results 1047 JY8QFUQ01BBCXQ No results 1048 JY8QFUQ01DRMBU unknown (see comment) Homsap IGHV3-7*03 F (see comment) 460 67.58 148/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (67,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1049 JY8QFUQ01C35AN No results 1050 JY8QFUQ01DSILW No results 1051 JY8QFUQ01DFH83 No results 1052 JY8QFUQ01ARLLN unproductive Homsap IGHV3-7*01 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.37.11] CGRDERGADLPNDS# out-of-frame + in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 189 in the user submitted sequence), (cause frameshift) tctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctgggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1053 JY8QFUQ01DK988 No results 1054 JY8QFUQ01AZSSK No results 1055 JY8QFUQ01AJ0GL No results 1056 JY8QFUQ01BO45B unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 844 88.73 189/213 nt 87.32 186/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 7 8 X 7.8.X [0.16.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) ctggattcgtcttggcgactatgcgatgagctgggtccggcaggctccagggaggggctggagtgggCtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1057 JY8QFUQ01BS4SB No results 1058 JY8QFUQ01DUW53 No results 1059 JY8QFUQ01ALWWB No results 1060 JY8QFUQ01A9QTD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 910 90.87 199/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [2.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - gggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1061 JY8QFUQ01CCS8Y unknown (see comment) Homsap IGHV5-10-1*03 F 82 63.83 30/47 nt 61.7 29/47 nt X X X X.X.X [15.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 9 of V-REGION: 2 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggcaaggaccgatgggcccgttcggtggaggtgacgaagccaccagaga 1062 JY8QFUQ01BYQA7 No results 1063 JY8QFUQ01AWDZV No results 1064 JY8QFUQ01C3R1H unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 92.56 199/215 nt 92.09 198/215 nt 8 8 X 8.8.X [1.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccaggaaggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1065 JY8QFUQ01AYQO2 No results 1066 JY8QFUQ01DDCY9 No results 1067 JY8QFUQ01AUX9R unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 279 58.53 127/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (58,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccctaggtacatactggatgcactgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1068 JY8QFUQ01AGAC7 No results 1069 JY8QFUQ01CST73 productive Homsap IGHV3-9*01 F 792 85.25 185/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVKDLSGRPKDMHGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctgggttcagttttagcaattatgccatgcactgggtccgtcaagctccagggaagggcctgcaatgggtctcacgtattaattggaacagtggaaacatagcctatgcggcctctgtgaggggccgattcaccgtctccagagacgacgccgagcactccctgtatttacaaatgaatggtctgacaactgaagacacggccttatactattgtgtgaaagatttgtctggccgaccaaaggacatgcacggcatggacgtctggggccaagggaccacggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1070 JY8QFUQ01B5EL9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1071 JY8QFUQ01CQUI4 No results 1072 JY8QFUQ01C9ZRN No results 1073 JY8QFUQ01BYZS1 No results 1074 JY8QFUQ01CWZ9S No results 1075 JY8QFUQ01DBEG4 No results 1076 JY8QFUQ01BK3YR No results 1077 JY8QFUQ01A89Y3 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 1078 JY8QFUQ01CPW4K No results 1079 JY8QFUQ01B0AUU productive (see comment) Homsap IGHV4-61*08 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-18*01 F 3 10 7 10 10.7.10 [1.16.38.11] CTRGVYTYDSPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggtgcctccatcagcagtagtggtcactactggagttggatccggcagcccccagggaagggactggaattcattggaaaatctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatttcagtggacacgtccgagaaccagttctccctgagcctgaggtctgtgaccgctgcggacacggccctttattactgtacgaggggggtatacacttatgacagcccgtggggccaggggattcaggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttctt 1080 JY8QFUQ01DTQET No results 1081 JY8QFUQ01CAWWF No results 1082 JY8QFUQ01DSK89 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 942 92.27 203/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'GA' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift); agcctctggattGcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggGtgtgggtgtcacgtagtaatGAccgggggggactgacacagcctacgcggactccgtgaagggccgattcaAccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1083 JY8QFUQ01AV6IN No results 1084 JY8QFUQ01CIHK9 unknown (see comment) Homsap IGHV7-81*01 ORF 98 76.47 26/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctggattcagcctcgccacttatagtatgagtt 1085 JY8QFUQ01DC6KD productive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-1*01 F 1 8 8 10 8.8.10 [2.17.38.11] CTKDTFGREDYW in-frame - gcctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1086 JY8QFUQ01AWGAC unknown (see comment) Homsap IGHV3-23*05 F 88 53.85 56/104 nt 52.88 55/104 nt 7 8 X 7.8.X [1.17.X.X] null + No rearrangement found stop codons in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctctggattcgtcttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccac 1087 JY8QFUQ01AB5PD unknown (see comment) Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F (see comment) 345 66.1 117/177 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (66,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcactagaagtcccatgaattgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1088 JY8QFUQ01B631L No results 1089 JY8QFUQ01CGXM9 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1090 JY8QFUQ01AW87B No results 1091 JY8QFUQ01BA3U4 No results 1092 JY8QFUQ01BMGQY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame + ctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1093 JY8QFUQ01C04FC No results 1094 JY8QFUQ01CTB7Y No results 1095 JY8QFUQ01CYGJK unknown (see comment) Homsap IGHV4-61*06 ORF (see comment) 328 61.11 132/216 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (61,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1096 JY8QFUQ01CKMH6 unknown (see comment) Homsap IGHV3-13*02 F 87 51.94 67/129 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found ctctggattcagcttaagttcttatggcatgaactgggtccgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact 1097 JY8QFUQ01B01ZN No results 1098 JY8QFUQ01A3GGK No results 1099 JY8QFUQ01BBM9Y No results 1100 JY8QFUQ01CQUMX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 506 87.79 115/131 nt 87.02 114/131 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 1 15 8.1.15 [1.17.16.11] CVRVKRFGSGNVLFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 86 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccaacagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 1101 JY8QFUQ01DJV40 No results 1102 JY8QFUQ01C8PC1 productive Homsap IGHV3-7*01 F 1030 97.69 211/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + tctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 1103 JY8QFUQ01B70IY No results 1104 JY8QFUQ01DC1VC unproductive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASIFGSGSPG##YYYGMDVW out-of-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttgggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggcctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 1105 JY8QFUQ01DO9NG No results 1106 JY8QFUQ01C24ZT productive Homsap IGHV3-9*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-20*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDMGYTWKYIDHW in-frame + ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1107 JY8QFUQ01AQSH7 No results 1108 JY8QFUQ01DWGXO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 730 81.28 178/219 nt 79.91 175/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 10 8.8.10 [2.17.37.11] CAKDDSAGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) agcctccggattcatcttcagtgccgcttggatggagtgggtccgccaagttccagggcacgggctcgtgtgggtcgcgcgtatcgagagtagtggcagcggcaCacgtttacgcggactacgtgaagggccgattcaccgtctccagagacaacgccatgaacatagtgtatcttcGaaatgaattctctgactgccgaggacacggtgtgtattactgcgcaaaggatgattcggccggccttgaccattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1109 JY8QFUQ01ASB5I No results 1110 JY8QFUQ01DCWY7 productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1111 JY8QFUQ01BVEDT productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 1112 JY8QFUQ01BW39X unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1113 JY8QFUQ01A2Z61 No results 1114 JY8QFUQ01CMY95 No results 1115 JY8QFUQ01CPVHO No results 1116 JY8QFUQ01DRPK1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1117 JY8QFUQ01DDZDR unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 91.36 201/220 nt 10 7 X 10.7.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtgataatttctactggggctggatccgccagccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgaaccggtgacggtgtcgtggaactcag 1118 JY8QFUQ01CWDLL No results 1119 JY8QFUQ01DKIIE No results 1120 JY8QFUQ01DUAQJ No results 1121 JY8QFUQ01BZSHA No results 1122 JY8QFUQ01BVUN8 No results 1123 JY8QFUQ01BQK5C productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1124 JY8QFUQ01DEC6U No results 1125 JY8QFUQ01DJDJH No results 1126 JY8QFUQ01A5Z0G productive Homsap IGHV4-30-4*07 F, or Homsap IGHV4-31*01 F or Homsap IGHV4-31*02 F or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F or Homsap IGHV4-31*06 F or Homsap IGHV4-31*07 F or Homsap IGHV4-31*08 F or Homsap IGHV4-34*09 F or Homsap IGHV4-59*06 F (see comment) 248 75.0 69/92 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 X X 18 X.X.18 [X.X.30.11] CARSAYCGADCYSADYLQHW in-frame - Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccgtcagcaacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 1127 JY8QFUQ01AN2IT No results 1128 JY8QFUQ01A7NI5 No results 1129 JY8QFUQ01C0IMB No results 1130 JY8QFUQ01DR8PG productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 925 90.99 202/222 nt 90.54 201/222 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgccCcccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc 1131 JY8QFUQ01DC95U No results 1132 JY8QFUQ01DQ0U7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1133 JY8QFUQ01DRSJM No results 1134 JY8QFUQ01CGGKR No results 1135 JY8QFUQ01DIWKI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1136 JY8QFUQ01A604Q No results 1137 JY8QFUQ01CBA2P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccgtgacggtgtcgtggaactcag 1138 JY8QFUQ01DQ2FL No results 1139 JY8QFUQ01BT3ET unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 104 75.68 28/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcagtatttataattattggatgaattgg 1140 JY8QFUQ01CUB57 No results 1141 JY8QFUQ01B2KH9 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 967 96.62 200/207 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQIDYGDFSRHGLDVW in-frame + aactttaccggctactggatcggctgggtgcgccagcggcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccatccttccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaaatagactacggtgacttctctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1142 JY8QFUQ01BZJNZ unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1143 JY8QFUQ01AZJQY No results 1144 JY8QFUQ01BY4UF No results 1145 JY8QFUQ01CYT8I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtaatgtctcctagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 1146 JY8QFUQ01DWMEP No results 1147 JY8QFUQ01C9FUL unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*04 F or Homsap IGHV4-34*06 F or Homsap IGHV4-34*07 F or Homsap IGHV4-34*09 F or Homsap IGHV4-34*10 F or Homsap IGHV4-34*12 F or Homsap IGHV4-59*10 F 103 58.75 47/80 nt 8 X X 8.X.X [2.16.X.X] null + No rearrangement found gtctatggtgggtccttcagtacttactactggacatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1148 JY8QFUQ01CW2ZQ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 1149 JY8QFUQ01DJ6VW No results 1150 JY8QFUQ01BIZZ1 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1151 JY8QFUQ01DLX1J No results 1152 JY8QFUQ01A00IV No results 1153 JY8QFUQ01C8PKK No results 1154 JY8QFUQ01DA5XZ No results 1155 JY8QFUQ01DK0VJ No results 1156 JY8QFUQ01CGZHZ No results 1157 JY8QFUQ01C2JYS No results 1158 JY8QFUQ01DJJED No results 1159 JY8QFUQ01C6R2Q unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 87 51.94 67/129 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 1160 JY8QFUQ01DRI4N No results 1161 JY8QFUQ01A8XXA productive Homsap IGHV3-11*01 F 938 93.87 199/212 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [X.17.38.11] CARDLQLGDDSGFSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gattcaccctcagtgactactacatgacttggatccgccaggctccagggaaggggctggagtgggtttcgtacattagtagtctcactagttccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgagagatcttcagctgggggatgatagtgggttttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1162 JY8QFUQ01C72YN No results 1163 JY8QFUQ01C05LQ No results 1164 JY8QFUQ01C89I5 No results 1165 JY8QFUQ01CO70A No results 1166 JY8QFUQ01A9Y62 No results 1167 JY8QFUQ01BMSRM unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaataCgtggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1168 JY8QFUQ01BCUQT No results 1169 JY8QFUQ01CP7NH productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 688 80.09 173/216 nt 79.17 171/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.16.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaagggccggagtgggtggccaacatatccccagacggaatacgaaatacttttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1170 JY8QFUQ01AP0N2 unproductive Homsap IGHV4-61*02 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-16*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREHSSSIGGERELDS## out-of-frame + tgtctggtggccccatcagcagtagtggcttcgcctggacctggatccggcagaccgccgggaagggactggagtggatcggacgtgtttatggtagtgggaataccaattacagtccttccctccagagtcgagtcaccatatcagtagagacgtccaagaatcagttctccctgaggttgacttctgtgaccgccgcagacacgggcctatattactgtgcgagagaacatagtagttcgattggcggagagagagaacttgactcctggggccagggaacccgaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1171 JY8QFUQ01A4CK6 No results 1172 JY8QFUQ01CPBZS No results 1173 JY8QFUQ01DRYJ8 No results 1174 JY8QFUQ01BF63V No results 1175 JY8QFUQ01CPQ1I No results 1176 JY8QFUQ01A6S5X No results 1177 JY8QFUQ01BFEB0 No results 1178 JY8QFUQ01A5T2M No results 1179 JY8QFUQ01BHKZ9 No results 1180 JY8QFUQ01CQJTH No results 1181 JY8QFUQ01DGCF0 No results 1182 JY8QFUQ01BLI8D No results 1183 JY8QFUQ01AQO2N unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 246 84.06 58/69 nt 8 X X 8.X.X [0.14.X.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttcccca 1184 JY8QFUQ01AKIMH No results 1185 JY8QFUQ01BK3VC No results 1186 JY8QFUQ01B18O2 No results 1187 JY8QFUQ01CM65D unknown (see comment) Homsap IGHV3-30*09 F, or Homsap IGHV3-33*01 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 363 64.22 131/204 nt 63.73 130/204 nt 8 7 X 8.7.X [1.17.34.X] null + No rearrangement found Low V-REGION identity (64,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1188 JY8QFUQ01CDTPI No results 1189 JY8QFUQ01DHVD2 No results 1190 JY8QFUQ01DIQYK productive (see comment) Homsap IGHV1-8*01 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.37.11] CARGRGYGSYADHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaaGcccccacagtgccaatatcgtctacgcgcagaaattcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1191 JY8QFUQ01DC8AC No results 1192 JY8QFUQ01CT6QT No results 1193 JY8QFUQ01DSZ8X unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 730 81.74 179/219 nt 80.82 177/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [2.17.38.11] CARIWDSWSG#FDVW out-of-frame - Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 44 of V-REGION: 'CAA' (3 nucleotides at position 47 to 49 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); gcctctggattcccctttagtgtgtactggatgtactgggtccgccCAAaagtcccgggaagggggccggtatgggtcgcacgtatcCagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1194 JY8QFUQ01AX7M1 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 166 58.21 78/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found tctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1195 JY8QFUQ01C5CLM No results 1196 JY8QFUQ01DFYDB No results 1197 JY8QFUQ01BOEUU No results 1198 JY8QFUQ01BJ9BI unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*01 F 402 92.55 87/94 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 1 X X X X.X.X [X.X.31.11] CAKDELPWDTIEYYFDY# out-of-frame + ctctggattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattgggccagggaagcctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1199 JY8QFUQ01DSOKK productive Homsap IGHV3-11*01 F 942 92.27 203/220 nt Homsap IGHJ6*01 F 252 88.89 56/63 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CVRYWGSYYYYNGLDVW in-frame - gcctctgggattcaccttcactgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtggtggtagaaccattgcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatattggggcagctactattactataacggtctggacgtctgggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1200 JY8QFUQ01DB8H0 No results 1201 JY8QFUQ01BBHB9 No results 1202 JY8QFUQ01A2SDF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 315 60.37 131/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (60,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactgggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccctccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 1203 JY8QFUQ01CUBOD No results 1204 JY8QFUQ01BP4KM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 449 67.44 145/215 nt 66.05 142/215 nt 8 8 X 8.8.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (67,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'ATGGTGCATGCTATGT' (16 nucleotides at position 109 to 124 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'TCTGGGGC' (8 nucleotides at position 133 to 140 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 2 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactaATGGTGCATGCTATGTcgccgactTCTGGGGCcagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1205 JY8QFUQ01AVYPI No results 1206 JY8QFUQ01B8SVY No results 1207 JY8QFUQ01AU3G2 No results 1208 JY8QFUQ01BHUZH No results 1209 JY8QFUQ01BV4GW productive Homsap IGHV4-39*02 F 839 86.88 192/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggacgtggtcatcgcctgcctggtccagggcttcttccccg 1210 JY8QFUQ01AD9B1 No results 1211 JY8QFUQ01ARPTV No results 1212 JY8QFUQ01DH04C unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.16.38.11] CARKRVPGGTFYGTT# out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaagggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggactactgggccagggaaccctggtcaccgtctcctcagccgtccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 1213 JY8QFUQ01BNGHE No results 1214 JY8QFUQ01ALASO No results 1215 JY8QFUQ01C8ZD0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 563 72.94 159/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (72,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1216 JY8QFUQ01BMX3R No results 1217 JY8QFUQ01CF8LE No results 1218 JY8QFUQ01BRBF4 No results 1219 JY8QFUQ01DFQZQ No results 1220 JY8QFUQ01DDPAR No results 1221 JY8QFUQ01AR8WH No results 1222 JY8QFUQ01BB4FI unknown (see comment) Homsap IGHV7-81*01 ORF 156 60.95 64/105 nt 8 8 X 8.8.X [0.17.1.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccaggcttcttcccca 1223 JY8QFUQ01AIT8M unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 467 68.37 147/215 nt 67.91 146/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1224 JY8QFUQ01C2NS9 No results 1225 JY8QFUQ01AZ5C6 No results 1226 JY8QFUQ01CTWUE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 756 82.95 180/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1227 JY8QFUQ01AQY8E No results 1228 JY8QFUQ01C9LXB No results 1229 JY8QFUQ01DRL69 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 1230 JY8QFUQ01CARXR No results 1231 JY8QFUQ01CKVI0 No results 1232 JY8QFUQ01A4RVS unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt 8 7 X 8.7.X [4.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 1233 JY8QFUQ01C41HM unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F (see comment) 322 64.77 114/176 nt 64.2 113/176 nt 8 8 X 8.8.X [1.16.24.X] null + No rearrangement found Low V-REGION identity (64,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcactagaagtcccatgaattgggtccgccaggctccggggaagggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 1234 JY8QFUQ01B8HKV unknown (see comment) Homsap IGHV4-61*02 F (see comment) 671 78.44 171/218 nt 10 7 X 10.7.X [1.17.37.X] null - No rearrangement found Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1235 JY8QFUQ01A1SBX No results 1236 JY8QFUQ01DOHBI No results 1237 JY8QFUQ01DMOR8 No results 1238 JY8QFUQ01BGVNK No results 1239 JY8QFUQ01A6GVM productive (see comment) Homsap IGHV1-2*02 F 790 85.51 183/214 nt 84.11 180/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 207 to 207 in the user submitted sequence), (cause frameshift); tggatacattttcaccggGctactatttacactgggngcgccaggccgctggacaagggcttgagtggatgggatAcaatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatCattttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1240 JY8QFUQ01CIBS1 No results 1241 JY8QFUQ01CH2HJ No results 1242 JY8QFUQ01C5WR5 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 197 95.35 41/43 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtcccca 1243 JY8QFUQ01DAQWO No results 1244 JY8QFUQ01DDXDI No results 1245 JY8QFUQ01BHLRQ No results 1246 JY8QFUQ01DQ3GA unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1247 JY8QFUQ01BNQZ4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 474 82.61 114/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 1248 JY8QFUQ01C2265 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 89 58.57 41/70 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccc 1249 JY8QFUQ01CSEV0 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 795 85.98 184/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-21*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSVGRYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tcgggggttcagcgtcaataataacttcatgacttggttccgccaggttccagggaaggggctggagtgggtctcagttatctatacaaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccgagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtactactgtgcgagagaatttcgggcgccttctgtgggcagatatggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1250 JY8QFUQ01A3SXJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1251 JY8QFUQ01ASIZV No results 1252 JY8QFUQ01DGWCG unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 83.87 182/217 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag 1253 JY8QFUQ01CS0CM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 503 93.04 107/115 nt 8 8 X 8.8.X [1.17.4.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagac 1254 JY8QFUQ01CYKYB No results 1255 JY8QFUQ01AF6RU unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 278 64.9 98/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found Low V-REGION identity (64,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 1256 JY8QFUQ01B5FVD No results 1257 JY8QFUQ01A1IOS No results 1258 JY8QFUQ01DPWH7 No results 1259 JY8QFUQ01BDH34 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1260 JY8QFUQ01BHLIP No results 1261 JY8QFUQ01DEJND unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 259 72.12 75/104 nt 8 7 X 8.7.X [1.17.1.X] null + No rearrangement found Low V-REGION identity (72,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttcctcca 1262 JY8QFUQ01A7P9Y No results 1263 JY8QFUQ01CCKWW No results 1264 JY8QFUQ01BJYX3 No results 1265 JY8QFUQ01CROHU No results 1266 JY8QFUQ01AVYK5 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 169 76.27 45/59 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found ctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca 1267 JY8QFUQ01AFCOL No results 1268 JY8QFUQ01AZOHA No results 1269 JY8QFUQ01DQPKO No results 1270 JY8QFUQ01A0KS4 No results 1271 JY8QFUQ01BPLHT No results 1272 JY8QFUQ01AJKSG No results 1273 JY8QFUQ01CR0BH No results 1274 JY8QFUQ01B8REL No results 1275 JY8QFUQ01DVIPJ No results 1276 JY8QFUQ01AP99O No results 1277 JY8QFUQ01CZYVE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 879 89.09 196/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + ctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1278 JY8QFUQ01BJG1Z productive Homsap IGHV4-61*02 F 960 93.18 205/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + ctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1279 JY8QFUQ01CYA4K No results 1280 JY8QFUQ01BLI2G No results 1281 JY8QFUQ01DV6CZ No results 1282 JY8QFUQ01C8713 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1283 JY8QFUQ01ANMZ3 No results 1284 JY8QFUQ01DOD03 No results 1285 JY8QFUQ01CGBI4 No results 1286 JY8QFUQ01CJK9L No results 1287 JY8QFUQ01AA6QP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + tctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1288 JY8QFUQ01C2R2R No results 1289 JY8QFUQ01BPPKV productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 854 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 7 8 10 7.8.10 [1.17.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) ctctggattcacttcagtagatactggatgcactgggtccgccaggctccagggaatggggctggantggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1290 JY8QFUQ01BW5D4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 85.98 184/214 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.16.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) tctggattcacatttagaagctattccatgaattggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 1291 JY8QFUQ01BSEMY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) tctggatccagtttcagtggtttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgctttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1292 JY8QFUQ01BSEQW No results 1293 JY8QFUQ01CGVDD unknown (see comment) Homsap IGHV4-61*02 F (see comment) 262 83.78 62/74 nt 10 X X 10.X.X [1.13.X.X] null + No rearrangement found Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgcctggatccggcagccc 1294 JY8QFUQ01DKZY8 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 1295 JY8QFUQ01ABF0G No results 1296 JY8QFUQ01DFO71 No results 1297 JY8QFUQ01AOLHE productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 732 82.71 177/214 nt 82.24 176/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.16.38.11] CARDWGGSFDRYYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1298 JY8QFUQ01CCCWF No results 1299 JY8QFUQ01CV38P No results 1300 JY8QFUQ01DHU9H No results 1301 JY8QFUQ01A8R7D No results 1302 JY8QFUQ01AFEL3 No results 1303 JY8QFUQ01C6OUF No results 1304 JY8QFUQ01BUCPI No results 1305 JY8QFUQ01DGGI5 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1306 JY8QFUQ01C9LSL No results 1307 JY8QFUQ01CLT61 No results 1308 JY8QFUQ01B7VCF productive (see comment) Homsap IGHV4-61*02 F (see comment) 672 78.64 173/220 nt 78.18 172/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.37.11] CARDRRRSIAGARHFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggtggccccaccatcgatgatggtgatttgtggacctggatccggcagcccgccggcaagggactggaatggatcggttatgtctatgatgggcggggcaccaactccaaccctccctccggagtcgcgttaccctgtcacaagacacctcaaacaatcagttcttcttgaggttgaagtctgtgaccgcctcagacacggccgtctattactgtgcgcgagaccgccgtaggtcgattgccggagcgagacactttgactcctggggccagggaatcctggccaccgtcgccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1309 JY8QFUQ01CX09A No results 1310 JY8QFUQ01DS2IL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1311 JY8QFUQ01BJS3X No results 1312 JY8QFUQ01B9JVU No results 1313 JY8QFUQ01CTJN4 No results 1314 JY8QFUQ01A15NY No results 1315 JY8QFUQ01AKU5E No results 1316 JY8QFUQ01DDRDF No results 1317 JY8QFUQ01CIM27 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 845 88.37 190/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.16.38.11] CARPPSGNLR*LR##W out-of-frame + stop codons in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctggattcagtttcagtgactactacatgagttggatccgccaggctccagggaggggctggagtgggAtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagacccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1318 JY8QFUQ01CN504 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1319 JY8QFUQ01C4DMZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatcccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 1320 JY8QFUQ01CUZGQ No results 1321 JY8QFUQ01B2PD2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found cctctggattcatcttcagtagctactggatgcactggg 1322 JY8QFUQ01AK2U7 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1323 JY8QFUQ01CBZLK No results 1324 JY8QFUQ01DDBZE No results 1325 JY8QFUQ01C1F2F No results 1326 JY8QFUQ01ANVQ1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccgggcttcttccccca 1327 JY8QFUQ01BUDKT productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 822 89.27 183/205 nt 87.8 180/205 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'GAC' (3 nucleotides at position 52 to 54 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift) ctctggtgactcccacttctggagctggatccggcagcccccgggcaaaggGACcgtggagtggattggttatgtctataacagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 1328 JY8QFUQ01AOUHJ No results 1329 JY8QFUQ01A781M No results 1330 JY8QFUQ01AI9X8 No results 1331 JY8QFUQ01CCSB5 No results 1332 JY8QFUQ01BM6J4 No results 1333 JY8QFUQ01AI0EO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1334 JY8QFUQ01CF5LR No results 1335 JY8QFUQ01DI64T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1336 JY8QFUQ01AMGQO No results 1337 JY8QFUQ01BL0WC productive (see comment) Homsap IGHV3-7*02 F, or Homsap IGHV3-7*03 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tccggattcattttggtgactattggatgagctgggtccgccaggttccagggaaaggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 1338 JY8QFUQ01CI2RN No results 1339 JY8QFUQ01DBKKS No results 1340 JY8QFUQ01CGQRQ No results 1341 JY8QFUQ01AJJSD unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1342 JY8QFUQ01DJRW9 No results 1343 JY8QFUQ01BT69S No results 1344 JY8QFUQ01BH3O9 No results 1345 JY8QFUQ01DKVGF No results 1346 JY8QFUQ01DT06M No results 1347 JY8QFUQ01CTS9U No results 1348 JY8QFUQ01BO326 No results 1349 JY8QFUQ01AZLQP No results 1350 JY8QFUQ01BQ2TE unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 116 96.0 24/25 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tccggggacagtgtctctaccaaca 1351 JY8QFUQ01AEAZN No results 1352 JY8QFUQ01AJ6QO No results 1353 JY8QFUQ01C9GES No results 1354 JY8QFUQ01DVP6C No results 1355 JY8QFUQ01BK8J7 No results 1356 JY8QFUQ01B6GEZ No results 1357 JY8QFUQ01CX2G5 No results 1358 JY8QFUQ01CT4TV No results 1359 JY8QFUQ01AHIYN No results 1360 JY8QFUQ01DSN5H unknown (see comment) Homsap IGHV4-31*06 F, or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*04 F 140 58.72 64/109 nt 10 7 X 10.7.X [2.17.X.X] null - No rearrangement found gtctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 1361 JY8QFUQ01DR0EH No results 1362 JY8QFUQ01BPUDU No results 1363 JY8QFUQ01DA687 productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1364 JY8QFUQ01CUQXS No results 1365 JY8QFUQ01DE6AA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [2.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1366 JY8QFUQ01CZVUB unknown (see comment) Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 96.79 211/218 nt 8 8 X 8.8.X [2.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) agcctctggattcaggtttagcatctattggatgagctgggtcgccaggctccagggaaggggctggagtggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 1367 JY8QFUQ01CVJ6V No results 1368 JY8QFUQ01A7KDU unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1369 JY8QFUQ01B4FNK unknown (see comment) Homsap IGHV3-72*01 F 110 53.85 70/130 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 1370 JY8QFUQ01DGFLY productive Homsap IGHV1-69*08 F 930 92.99 199/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame + tggaggctccttcggcagctacactatcacctgggtgcgacaggcccctggacaagggcttgagtggatgggaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1371 JY8QFUQ01CC6Q7 No results 1372 JY8QFUQ01CC0O7 No results 1373 JY8QFUQ01DBP2G unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 434 77.03 114/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (77,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca 1374 JY8QFUQ01A4FRD No results 1375 JY8QFUQ01AZQDI No results 1376 JY8QFUQ01CY2SC No results 1377 JY8QFUQ01A7W88 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 1378 JY8QFUQ01DP5C8 No results 1379 JY8QFUQ01A68NC No results 1380 JY8QFUQ01C968T unknown (see comment) Homsap IGHV3-74*03 F 113 54.33 69/127 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1381 JY8QFUQ01A2IM0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 151 57.25 75/131 nt 8 6 X 8.6.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccagcatggagacgtggtcgtcgcatgcctggtccagggcttcttccccc 1382 JY8QFUQ01BHB4N No results 1383 JY8QFUQ01BNESV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARRTITAAGRGDDYW in-frame + ctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1384 JY8QFUQ01AVAWG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 751 82.87 179/216 nt 82.41 178/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaagggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1385 JY8QFUQ01DUNEQ No results 1386 JY8QFUQ01CDFK1 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcc 1387 JY8QFUQ01AMW7J No results 1388 JY8QFUQ01DEGDT No results 1389 JY8QFUQ01B3HPK No results 1390 JY8QFUQ01AFBP7 No results 1391 JY8QFUQ01BSOH5 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1392 JY8QFUQ01DULGP productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P (see comment) 357 75.38 98/130 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 X 5 13 X.5.13 [X.X.38.11] CATSPSDFDRRWGYW in-frame + Low V-REGION identity (75,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatttagctttagaaccttttggatgagctggggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 1393 JY8QFUQ01CT5ZJ unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac 1394 JY8QFUQ01DWD6E productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 1395 JY8QFUQ01AHAAA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDFFIGGYYGMDV# out-of-frame + in FR3-IMGT at codon 94 of V-REGION: 'CG' (2 nucleotides at position 186 to 187 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagccCGtgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctgggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgtgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 1396 JY8QFUQ01BSWTU unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F (see comment) 286 72.57 82/113 nt 8 8 X 8.8.X [2.17.2.X] null + No rearrangement found Low V-REGION identity (72,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcatcgcctgcctggtccagggcttcttccccca 1397 JY8QFUQ01DXHWW unknown (see comment) Homsap IGHV3-16*01 ORF, or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-35*01 ORF or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 139 88.57 31/35 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaact 1398 JY8QFUQ01CQG7G productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 777 85.05 182/214 nt 84.58 181/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [0.17.37.11] CARRSGRDGGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 75 of V-REGION: 1 nucleotides (from position 126 in the user submitted sequence), (cause frameshift) ctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggcgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1399 JY8QFUQ01CHINB No results 1400 JY8QFUQ01CWJ1D No results 1401 JY8QFUQ01BWRJM No results 1402 JY8QFUQ01APTE0 No results 1403 JY8QFUQ01DH93K No results 1404 JY8QFUQ01A74DO No results 1405 JY8QFUQ01A3LNS No results 1406 JY8QFUQ01AX86C No results 1407 JY8QFUQ01C49LY No results 1408 JY8QFUQ01BP7AC No results 1409 JY8QFUQ01BSO0Y unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1410 JY8QFUQ01BS5BQ No results 1411 JY8QFUQ01CEMVD No results 1412 JY8QFUQ01DG5H6 No results 1413 JY8QFUQ01DFDK1 No results 1414 JY8QFUQ01CAA11 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF (see comment) 299 70.0 91/130 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (70,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaacgtggtcatcgcctgcctggtccagggcctcttccccca 1415 JY8QFUQ01A3VDJ unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1416 JY8QFUQ01CNXZU No results 1417 JY8QFUQ01BLPYK No results 1418 JY8QFUQ01BOG7A productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1419 JY8QFUQ01B21I3 No results 1420 JY8QFUQ01CD61F unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F 144 59.26 64/108 nt 8 8 X 8.8.X [0.17.2.X] null + No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaagggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1421 JY8QFUQ01A2TDY No results 1422 JY8QFUQ01C8YUG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1423 JY8QFUQ01AUCXY No results 1424 JY8QFUQ01CWYOD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttgggggcctggggaaacccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1425 JY8QFUQ01C9RSP No results 1426 JY8QFUQ01A5ZE0 No results 1427 JY8QFUQ01CQUPE No results 1428 JY8QFUQ01AJALL unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1429 JY8QFUQ01C42EK No results 1430 JY8QFUQ01C9WTB No results 1431 JY8QFUQ01A2U9H unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 83.87 182/217 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag 1432 JY8QFUQ01BTOWM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 382 76.12 102/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1433 JY8QFUQ01AG2OG productive Homsap IGHV3-64*02 F (see comment) 769 84.26 182/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRPMAGFHGILYDNW in-frame + Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1434 JY8QFUQ01C26A4 No results 1435 JY8QFUQ01CB0O0 No results 1436 JY8QFUQ01DL2NW No results 1437 JY8QFUQ01DUBH3 unknown (see comment) Homsap IGHV3-22*01 P, or Homsap IGHV3-22*02 P 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tgtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 1438 JY8QFUQ01CLXH8 No results 1439 JY8QFUQ01AEUEN unproductive (see comment) Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1440 JY8QFUQ01AUSWA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 273 69.11 85/123 nt 8 8 X 8.8.X [1.17.7.X] null + No rearrangement found Low V-REGION identity (69,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 1441 JY8QFUQ01CTJC0 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 1442 JY8QFUQ01BI9UV No results 1443 JY8QFUQ01BVNHA No results 1444 JY8QFUQ01BDGPP No results 1445 JY8QFUQ01CHY6B No results 1446 JY8QFUQ01DRO6Z productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 973 92.11 210/228 nt 91.67 209/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [2.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 1447 JY8QFUQ01DULSH No results 1448 JY8QFUQ01BVM0S No results 1449 JY8QFUQ01DKWYM No results 1450 JY8QFUQ01DD498 No results 1451 JY8QFUQ01BBVFC productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttacagtttcaactgggtccgccCaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1452 JY8QFUQ01ATQS0 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 633 77.1 165/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01ATQS0 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1453 JY8QFUQ01DJJ2U No results 1454 JY8QFUQ01BLKB1 No results 1455 JY8QFUQ01ARGE6 No results 1456 JY8QFUQ01BUAN5 No results 1457 JY8QFUQ01DMFF2 No results 1458 JY8QFUQ01DEVVA No results 1459 JY8QFUQ01AX6JI No results 1460 JY8QFUQ01CYZSJ productive Homsap IGHV3-11*01 F 823 87.04 188/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-7*01 F 1 8 8 15 8.8.15 [1.17.38.11] CVRESRSWTGSTLPAYW in-frame + tctggattcaccttcagtgactattacatgagttggtaccgccaggctccaggtcaggggctggagtggctttcatatataagtcaaactggcaaaaccacatacttcgcagactctgtgaagggccgattcaccatctccagggacaatgccaagacatcagtgtttctgcaaatgaacagcctgagagttgacgacacggccgtgtatttttgtgtgagagaatctaggagttggactggaagtacacttccagcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 1461 JY8QFUQ01C2H4R No results 1462 JY8QFUQ01A2DHA No results 1463 JY8QFUQ01CCUUB No results 1464 JY8QFUQ01A6213 unproductive Homsap IGHV1-3*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDGESLGGD#FDYW out-of-frame + tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1465 JY8QFUQ01BMD3G unknown (see comment) Homsap IGHV1-2*02 F 491 87.4 111/127 nt 86.61 110/127 nt 7 8 X 7.8.X [0.17.9.X] null + No rearrangement found in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) tggatacatttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg 1466 JY8QFUQ01CDBCN unknown (see comment) Homsap IGHV3-66*02 F (see comment) 687 79.91 171/214 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1467 JY8QFUQ01DF0MT No results 1468 JY8QFUQ01CF4HL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 401 89.0 89/100 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca 1469 JY8QFUQ01C8D76 No results 1470 JY8QFUQ01DW98C No results 1471 JY8QFUQ01C6KJV No results 1472 JY8QFUQ01CT0HD productive (see comment) Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.16.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggagccctggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 1473 JY8QFUQ01BZ11O No results 1474 JY8QFUQ01C83Q9 No results 1475 JY8QFUQ01CUE0P No results 1476 JY8QFUQ01C0R3Y No results 1477 JY8QFUQ01DSN92 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttgcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 1478 JY8QFUQ01DNURL No results 1479 JY8QFUQ01BL2YO productive Homsap IGHV3-11*01 F 855 88.48 192/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + ctctggattcaccttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggaatggatctcatatatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1480 JY8QFUQ01AL3MP No results 1481 JY8QFUQ01AJN29 No results 1482 JY8QFUQ01BC3V3 No results 1483 JY8QFUQ01C7F7K No results 1484 JY8QFUQ01AVMY4 No results 1485 JY8QFUQ01C8W2Q No results 1486 JY8QFUQ01CRZ6P No results 1487 JY8QFUQ01CMH9H No results 1488 JY8QFUQ01AX1TT No results 1489 JY8QFUQ01B6TW6 productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 388 91.4 85/93 nt 89.25 83/93 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1490 JY8QFUQ01A1UND productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1491 JY8QFUQ01ADO15 No results 1492 JY8QFUQ01AHJ9R unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 1493 JY8QFUQ01DTXW3 No results 1494 JY8QFUQ01ATI6H No results 1495 JY8QFUQ01AOK66 productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaatagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1496 JY8QFUQ01A6GAE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggaAGgtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1497 JY8QFUQ01BIWEF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaact 1498 JY8QFUQ01A50M4 unproductive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGKAGHTHYGLDV## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctgcattcaccttcagtagttatgctatgcactgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1499 JY8QFUQ01C8L2Z No results 1500 JY8QFUQ01BRQW6 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 105 100.0 21/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcactttcagtaa 1501 JY8QFUQ01DNLCD No results 1502 JY8QFUQ01DK6B2 No results 1503 JY8QFUQ01CSULX No results 1504 JY8QFUQ01AR3XO productive (see comment) Homsap IGHV3-7*03 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 65 to 66 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggaggggcgtgGAgagtgggtggccaaTcataaagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1505 JY8QFUQ01DFEJE No results 1506 JY8QFUQ01DMEUX No results 1507 JY8QFUQ01C0DJQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1508 JY8QFUQ01CT3AM productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1509 JY8QFUQ01BBQA5 No results 1510 JY8QFUQ01AZSN7 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 98 60.0 42/70 nt 58.57 41/70 nt 8 X X 8.X.X [0.14.X.X] null - No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) ctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1511 JY8QFUQ01AT9ZL No results 1512 JY8QFUQ01CYS4U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 270 68.25 86/126 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found Low V-REGION identity (68,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1513 JY8QFUQ01CCP15 No results 1514 JY8QFUQ01BB2S8 No results 1515 JY8QFUQ01DSXCD No results 1516 JY8QFUQ01BNWTF No results 1517 JY8QFUQ01BZVYZ No results 1518 JY8QFUQ01C7KGD No results 1519 JY8QFUQ01C4PQJ No results 1520 JY8QFUQ01CTOHD No results 1521 JY8QFUQ01AVF2G No results 1522 JY8QFUQ01C9SAD productive (see comment) Homsap IGHV4-39*03 F, or Homsap IGHV4-39*07 F 870 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggtggctccatcaacagtggtagttatcactggggCctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1523 JY8QFUQ01CTJGE productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1524 JY8QFUQ01BBTKL No results 1525 JY8QFUQ01C4OPG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1526 JY8QFUQ01CXEZM No results 1527 JY8QFUQ01DMH48 productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 1528 JY8QFUQ01DW6RS No results 1529 JY8QFUQ01CWB23 No results 1530 JY8QFUQ01DWHTO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 682 95.33 143/150 nt 94.67 142/150 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 X 8 8.X.8 [1.15.26.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 66 nucleotides (from position 73 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacacaccccccaacgatgggaacgtggtccgtcgcatgcctggtccagggccttcttcccccga 1531 JY8QFUQ01CZYGW No results 1532 JY8QFUQ01AL6QG No results 1533 JY8QFUQ01CGTYC No results 1534 JY8QFUQ01A7RTJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 492 84.06 116/138 nt 83.33 115/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggcGtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 1535 JY8QFUQ01C8WKL unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 92 51.8 72/139 nt 10 9 X 10.9.X [1.17.9.X] null - No rearrangement found stop codons ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1536 JY8QFUQ01CQAGH No results 1537 JY8QFUQ01AIGGL No results 1538 JY8QFUQ01B0I9T No results 1539 JY8QFUQ01BS4TM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 197 57.4 97/169 nt 8 8 X 8.8.X [1.17.22.X] null + No rearrangement found tctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 1540 JY8QFUQ01C233A unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*04 F or Homsap IGHV4-34*06 F or Homsap IGHV4-34*07 F or Homsap IGHV4-34*09 F or Homsap IGHV4-34*10 F or Homsap IGHV4-34*12 F 98 58.23 46/79 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found ctatggtgggtccttcagtacttactactggacatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1541 JY8QFUQ01AEBZX unknown (see comment) Homsap IGHV3-30*19 F (see comment) 298 74.55 82/110 nt 8 8 X 8.8.X [1.17.2.X] null + No rearrangement found Low V-REGION identity (74,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcatcgcctgcctggtccagggcttcttccccca 1542 JY8QFUQ01DHO1I No results 1543 JY8QFUQ01DVHFD productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1544 JY8QFUQ01DG1MM No results 1545 JY8QFUQ01C6NYA No results 1546 JY8QFUQ01AOIZ2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 876 96.77 180/186 nt 8 8 X 8.8.X [1.17.27.X] null + No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcca 1547 JY8QFUQ01BF3C4 No results 1548 JY8QFUQ01AF4P6 No results 1549 JY8QFUQ01AHA6F No results 1550 JY8QFUQ01B1R1V No results 1551 JY8QFUQ01AX41Q No results 1552 JY8QFUQ01AIX26 No results 1553 JY8QFUQ01A9NCZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1554 JY8QFUQ01C4MF5 No results 1555 JY8QFUQ01A8DGZ No results 1556 JY8QFUQ01ADA0I No results 1557 JY8QFUQ01CYDVX No results 1558 JY8QFUQ01CHSNE No results 1559 JY8QFUQ01DEI8T No results 1560 JY8QFUQ01A5AEL No results 1561 JY8QFUQ01BY3ME No results 1562 JY8QFUQ01BZ1UD No results 1563 JY8QFUQ01CSG2N No results 1564 JY8QFUQ01CX7CX No results 1565 JY8QFUQ01CPO8G No results 1566 JY8QFUQ01C4AN6 No results 1567 JY8QFUQ01A7DEU No results 1568 JY8QFUQ01AM9GW unproductive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDYW# out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1569 JY8QFUQ01CR49L productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1570 JY8QFUQ01B506K unknown (see comment) Homsap IGHV4-61*06 ORF (see comment) 328 61.11 132/216 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (61,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1571 JY8QFUQ01BP7DL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGEFYYETSGRRGFDYW in-frame + ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtctcacgtgtgaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacgctgtacttggaaatgaacagtctgagagtcgaggacacggctatgtattattgtgcaagaggagaattttattatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1572 JY8QFUQ01CS6JH productive Homsap IGHV3-7*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + tctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcgggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1573 JY8QFUQ01DC99E No results 1574 JY8QFUQ01CDR1Q No results 1575 JY8QFUQ01BWF7R No results 1576 JY8QFUQ01AF5F2 unknown (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1577 JY8QFUQ01CJG83 No results 1578 JY8QFUQ01AQA2P No results 1579 JY8QFUQ01C3DCT unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 85 51.49 69/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcacctttaacctctatgtcatgcactggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1580 JY8QFUQ01CEDL3 No results 1581 JY8QFUQ01BPHP1 No results 1582 JY8QFUQ01DC6L2 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 1583 JY8QFUQ01AMF2G No results 1584 JY8QFUQ01DSXER productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1585 JY8QFUQ01DESV3 No results 1586 JY8QFUQ01CCPG5 No results 1587 JY8QFUQ01AQXSC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 670 78.7 170/216 nt 78.24 169/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (78,70% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1588 JY8QFUQ01DQ1Q4 productive (see comment) Homsap IGHV4-61*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 9 7 15 9.7.15 [1.17.38.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctctggtgctccatcagcagtggtagtttctacCtggagctggatccggcagcccgccgggaagggactggagtggatggggcgtgtctatgccagtggaaccaccaagttcaacccctccctcaagagtcgagtcactttatcagtagacacgtccaagaaccagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1589 JY8QFUQ01A40Z9 No results 1590 JY8QFUQ01BT13P unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1591 JY8QFUQ01B42CS No results 1592 JY8QFUQ01DCAUV unknown (see comment) Homsap IGHV3-13*02 F 82 51.56 66/128 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found tctggattcagcttaagttcttatggcatgaactgggtccgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact 1593 JY8QFUQ01BOEMI No results 1594 JY8QFUQ01DGRKS No results 1595 JY8QFUQ01CYSQX unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 103 66.04 35/53 nt Homsap IGHD1-7*01 F 2 8 7 X 8.7.X [1.17.37.11] CARLDGHFD#LG out-of-frame + Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctgggggcccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1596 JY8QFUQ01CL5D9 No results 1597 JY8QFUQ01C7A04 unknown (see comment) Homsap IGHV1-3*01 F (see comment) 340 61.97 132/213 nt 61.5 131/213 nt Homsap IGHJ1*01 F, or Homsap IGHJ4*03 F or Homsap IGHJ5*02 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (61,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacagcttcactaactacaatatccattgggtgcgccaggccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1598 JY8QFUQ01A115T No results 1599 JY8QFUQ01DC99U No results 1600 JY8QFUQ01C7LLU No results 1601 JY8QFUQ01BSUYS No results 1602 JY8QFUQ01BWI1R No results 1603 JY8QFUQ01BD39D No results 1604 JY8QFUQ01ANEJ0 No results 1605 JY8QFUQ01CZFYF unknown (see comment) Homsap IGHV3-38-3*01 ORF 87 51.94 67/129 nt 8 7 X 8.7.X [1.17.10.X] null - No rearrangement found stop codons gtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccca 1606 JY8QFUQ01DSJJ1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 624 93.66 133/142 nt 91.55 130/142 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 10 7.1.10 [1.X.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01DSJJ1 ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) cctcaggattcaccttcagtagctacacagatcacgcggactccgtgaaTgggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1607 JY8QFUQ01B8BQK No results 1608 JY8QFUQ01AE5UH No results 1609 JY8QFUQ01DSSRA No results 1610 JY8QFUQ01AKT2V No results 1611 JY8QFUQ01AT43H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.16.38.11] CSKDTFGREDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 2 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccagggagggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1612 JY8QFUQ01DMC3P productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKINNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 1613 JY8QFUQ01BCGX5 unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 651 78.04 167/214 nt Homsap IGHJ2*01 F 27 61.11 11/18 nt 8 8 X 8.8.X [0.17.38.6] RTGD (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION identity (78,04% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctgggctgcctggtcaaggactacttccccgaaccggtgacagtgtcgtggaactcag 1614 JY8QFUQ01CSQQE productive Homsap IGHV4-61*02 F 987 94.55 208/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + ctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1615 JY8QFUQ01BDYZI No results 1616 JY8QFUQ01DAF6H unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1617 JY8QFUQ01A7MDG No results 1618 JY8QFUQ01BA4CQ No results 1619 JY8QFUQ01CATXG unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F or Homsap IGHV3-9*01 F or Homsap IGHV3-9*03 F 116 62.86 44/70 nt 61.43 43/70 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) ctctggattccggtttgatgattatgccatacattgggttcgcctgcctggtccagggcttcttccccca 1620 JY8QFUQ01A76UO No results 1621 JY8QFUQ01A9J93 No results 1622 JY8QFUQ01A8DDZ No results 1623 JY8QFUQ01DXIJH No results 1624 JY8QFUQ01BGTEX No results 1625 JY8QFUQ01DGTT9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 1626 JY8QFUQ01BYDQM No results 1627 JY8QFUQ01BB2G6 No results 1628 JY8QFUQ01BGV4K unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 190 76.92 50/65 nt 8 X X 8.X.X [0.13.X.X] null - No rearrangement found ctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggcttcttccccca 1629 JY8QFUQ01A8XJR productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 997 94.59 210/222 nt 93.69 208/222 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); tctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaacCcgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1630 JY8QFUQ01BVKDE No results 1631 JY8QFUQ01BBFMH No results 1632 JY8QFUQ01CSY85 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 93 52.27 69/132 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons tctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1633 JY8QFUQ01AJ1SS unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 100 53.12 68/128 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 1634 JY8QFUQ01CJL2W No results 1635 JY8QFUQ01CBN2X No results 1636 JY8QFUQ01CXT5I No results 1637 JY8QFUQ01DW8QQ No results 1638 JY8QFUQ01C466A No results 1639 JY8QFUQ01A6H47 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 637 82.26 153/186 nt 81.72 152/186 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.16.38.11] DSRNPRV# out-of-frame + Low V-REGION identity (82,26% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift) gagtgggtgccgccaggctccagggaagggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaacctcaggc 1640 JY8QFUQ01CB3G5 No results 1641 JY8QFUQ01BNQ9Y No results 1642 JY8QFUQ01ABDNP productive (see comment) Homsap IGHV3-7*01 F 805 86.11 186/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggaggggcgtgGAgagtgggtggccaaTcataaagtcagatggaagtgacaaatggtatgtggactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1643 JY8QFUQ01BLJQY No results 1644 JY8QFUQ01DNQRU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 1645 JY8QFUQ01AG942 unknown (see comment) Homsap IGHV3-23*05 F 97 54.81 57/104 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1646 JY8QFUQ01AWAV5 No results 1647 JY8QFUQ01AEHLA No results 1648 JY8QFUQ01CCCUV No results 1649 JY8QFUQ01A8KZQ productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1650 JY8QFUQ01C77C5 No results 1651 JY8QFUQ01CFYO5 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 55 100.0 11/11 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found ctctggattca 1652 JY8QFUQ01AW8AK No results 1653 JY8QFUQ01B7Y0I No results 1654 JY8QFUQ01BGOA2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 604 79.58 152/191 nt 8 8 X 8.8.X [2.17.28.X] null - No rearrangement found Low V-REGION identity (79,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacgcctgcctggtccagggcttcttccccca 1655 JY8QFUQ01ASF1C unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 929 91.4 202/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggagcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagagcatccccgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 1656 JY8QFUQ01DHAVX No results 1657 JY8QFUQ01DJLNB No results 1658 JY8QFUQ01DSWRX No results 1659 JY8QFUQ01CU3Q6 No results 1660 JY8QFUQ01DDW01 No results 1661 JY8QFUQ01BWZ4E No results 1662 JY8QFUQ01CZB0R No results 1663 JY8QFUQ01DO1CE No results 1664 JY8QFUQ01BYRY4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 83.8 181/216 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag 1665 JY8QFUQ01DKO56 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [2.17.38.11] CANASPV*LE#YFYYYGMDVW out-of-frame - stop codons gcctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1666 JY8QFUQ01BMXOK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 97.22 210/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattaGgtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatccccgaccagccccaaggtcttcccgntgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccc 1667 JY8QFUQ01ALR6B No results 1668 JY8QFUQ01A9M5C productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [2.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccGatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1669 JY8QFUQ01A6VX5 No results 1670 JY8QFUQ01CTAKI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 213 80.3 53/66 nt 8 X X 8.X.X [1.12.X.X] null - No rearrangement found Low V-REGION identity (80,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggcttcttcccca 1671 JY8QFUQ01BHD1H No results 1672 JY8QFUQ01BBU8N No results 1673 JY8QFUQ01DJWHU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1674 JY8QFUQ01BSNEK No results 1675 JY8QFUQ01B1925 No results 1676 JY8QFUQ01BFQJR No results 1677 JY8QFUQ01A765R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 494 92.17 106/115 nt 8 8 X 8.8.X [0.17.5.X] null + No rearrangement found tggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca 1678 JY8QFUQ01C34PH unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1679 JY8QFUQ01CZTSH No results 1680 JY8QFUQ01C6A2R No results 1681 JY8QFUQ01DWH6E unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 167 94.59 35/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttggttattatggcatgagctgg 1682 JY8QFUQ01DVPDB unproductive (see comment) Homsap IGHV4-61*01 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ5*02 F 97 64.71 33/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CTRGAVXL*QPV# out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcCccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacanttatgacagcccgtggggacaggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1683 JY8QFUQ01BBU79 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 139 63.75 51/80 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found stop codons tctggattcacctttagcagctatgccatgagctgggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca 1684 JY8QFUQ01CE73H No results 1685 JY8QFUQ01AV27O No results 1686 JY8QFUQ01B8EZR No results 1687 JY8QFUQ01AOGA6 No results 1688 JY8QFUQ01AFRYT No results 1689 JY8QFUQ01C98A9 productive Homsap IGHV1-18*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARENYYTSGIHSGFRHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggttacatctttaccacctatggtatcagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaacacttacaatggtaacacgaactatggacagaggatccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccgtatattattgtgcgagagaaaactactatacttcgggaattcattccggcttcaggcactggggccagggaaccctggtcaccgtctcctcagctccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1690 JY8QFUQ01AHYWT productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 678 79.91 171/214 nt 78.97 169/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'AGT' (3 nucleotides at position 137 to 139 in the user submitted sequence), (do not cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccCgtgaggggcgggcttatcgaAGTctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1691 JY8QFUQ01AZS8E unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 80 51.13 68/133 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1692 JY8QFUQ01CFTY8 No results 1693 JY8QFUQ01DTGVP No results 1694 JY8QFUQ01A6M8L No results 1695 JY8QFUQ01BIK9K No results 1696 JY8QFUQ01CQTRT No results 1697 JY8QFUQ01DMOXH No results 1698 JY8QFUQ01AFK77 No results 1699 JY8QFUQ01DC0HE No results 1700 JY8QFUQ01BSGS4 No results 1701 JY8QFUQ01C0P59 No results 1702 JY8QFUQ01CMY3L No results 1703 JY8QFUQ01DSU07 No results 1704 JY8QFUQ01CHJWZ unknown (see comment) Homsap IGHV3-66*02 F 748 92.49 160/173 nt 8 7 X 8.7.X [4.17.21.X] null + No rearrangement found tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta 1705 JY8QFUQ01BR08D productive (see comment) Homsap IGHV3-48*04 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatagcatgaactgggtccgccagactccagggaagggggtggagtggatttcatacatcggccgtggtggtgatgggatatactacgcggactccgtggaggaccgattGcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1706 JY8QFUQ01BPJB6 No results 1707 JY8QFUQ01BI4C1 No results 1708 JY8QFUQ01DF3F1 No results 1709 JY8QFUQ01BNFPE No results 1710 JY8QFUQ01DK75T No results 1711 JY8QFUQ01BA4G5 productive (see comment) Homsap IGHV3-11*01 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1712 JY8QFUQ01C8JNJ No results 1713 JY8QFUQ01AJRAI No results 1714 JY8QFUQ01C5U0P No results 1715 JY8QFUQ01DSUT3 No results 1716 JY8QFUQ01A501N No results 1717 JY8QFUQ01AKC7U No results 1718 JY8QFUQ01CUV5O unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F (see comment) 366 67.82 118/174 nt 8 10 X 8.10.X [1.17.21.X] null - No rearrangement found Low V-REGION identity (67,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1719 JY8QFUQ01B0PMZ No results 1720 JY8QFUQ01CCGCT unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 1721 JY8QFUQ01BWFT2 No results 1722 JY8QFUQ01DKW91 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 1723 JY8QFUQ01A86GB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-7*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKVFQVPGEHHFYYFGMNVW in-frame - cctctggattcatgtttaggaactatgccatgagttgggtccgccaggctccagggagggggctggagtgggtctcaactattagcaataatggaagccacacatactacgcagactccgtcaagggccggttcaccatctccagagacaattccaagaacacggtgtatatgcagatgaacaggctgagagtcgaggagacggccctgtactactgtgcgaaagtcttccaggtgcctggcgagcaccacttctactacttcggaatgaatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1724 JY8QFUQ01A7BSR No results 1725 JY8QFUQ01AGMEL No results 1726 JY8QFUQ01CTF5B unknown (see comment) Homsap IGHV3-23*05 F 87 51.94 67/129 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found stop codons cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccaggcttcttcc 1727 JY8QFUQ01AU61S productive Homsap IGHV1-24*01 F 957 94.39 202/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1728 JY8QFUQ01A2WKZ No results 1729 JY8QFUQ01AGQ6F No results 1730 JY8QFUQ01BOLV9 No results 1731 JY8QFUQ01CHRWV No results 1732 JY8QFUQ01BZMVP No results 1733 JY8QFUQ01BUEFY No results 1734 JY8QFUQ01DBD2S unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 355 63.59 131/206 nt 63.11 130/206 nt 8 8 X 8.8.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (63,59% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); gtctggattcaAttttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtcaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1735 JY8QFUQ01CFU2I No results 1736 JY8QFUQ01BDDZ2 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1737 JY8QFUQ01BHBIU No results 1738 JY8QFUQ01CURR2 No results 1739 JY8QFUQ01C53TF unproductive Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1740 JY8QFUQ01CUUA0 unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1741 JY8QFUQ01C0UXJ No results 1742 JY8QFUQ01A358V No results 1743 JY8QFUQ01CEAGF No results 1744 JY8QFUQ01CVR09 unproductive Homsap IGHV3-21*04 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F 128 68.97 40/58 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARAVSNQVDVW# out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcgccGttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagAttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctgggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1745 JY8QFUQ01DQ2MG No results 1746 JY8QFUQ01DLEQI No results 1747 JY8QFUQ01CUKWF No results 1748 JY8QFUQ01AL7F8 No results 1749 JY8QFUQ01A702R productive Homsap IGHV3-48*02 F (see comment) 724 81.48 176/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1750 JY8QFUQ01DHU2N productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1751 JY8QFUQ01DPCAF No results 1752 JY8QFUQ01B26JL productive Homsap IGHV3-9*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame - ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1753 JY8QFUQ01BPXVZ No results 1754 JY8QFUQ01C3YIQ No results 1755 JY8QFUQ01AD96J unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 709 79.73 177/222 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (79,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaatcacgttgtatctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 1756 JY8QFUQ01DCKY3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1757 JY8QFUQ01BSCCC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 94 of V-REGION: 'A' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctAggggcccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctcggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1758 JY8QFUQ01BTY9A No results 1759 JY8QFUQ01ABU7T No results 1760 JY8QFUQ01DQFTI No results 1761 JY8QFUQ01CZ8S7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1762 JY8QFUQ01B0QD1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 96.32 183/190 nt 95.26 181/190 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.29.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 94 of V-REGION: 25 nucleotides (from position 185 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtcttactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1763 JY8QFUQ01CUVTH unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac 1764 JY8QFUQ01BEARQ No results 1765 JY8QFUQ01DC4QI productive Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccaggcccagcatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 1766 JY8QFUQ01CL5V0 productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaagcgtggtcgtcgcatgcctggtccagggcttcttccccc 1767 JY8QFUQ01DALFI No results 1768 JY8QFUQ01ALIFQ No results 1769 JY8QFUQ01AO96D unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 817 87.32 186/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 7 X 8.7.X [1.16.38.11] CAKESLFGESS#YYFDDW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaagggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctgttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1770 JY8QFUQ01BYQY5 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1771 JY8QFUQ01A015U productive (see comment) Homsap IGHV3-30*13 F (see comment) 228 77.22 61/79 nt 75.95 60/79 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 X X 14 X.X.14 [X.X.26.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (77,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 87 of V-REGION: 12 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactatcacatgtactggatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1772 JY8QFUQ01DIXGW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1773 JY8QFUQ01ATDNN No results 1774 JY8QFUQ01A5728 No results 1775 JY8QFUQ01AZY3T unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 245 58.55 113/193 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (58,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 1776 JY8QFUQ01BZ5SX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt 89.19 198/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1777 JY8QFUQ01DOTS5 No results 1778 JY8QFUQ01B8BR0 No results 1779 JY8QFUQ01A9NA9 unknown (see comment) Homsap IGHV3-66*02 F 754 92.05 162/176 nt 8 7 X 8.7.X [5.17.21.X] null - No rearrangement found gcctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta 1780 JY8QFUQ01CV75P No results 1781 JY8QFUQ01BCGSW No results 1782 JY8QFUQ01A6XI0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 1783 JY8QFUQ01DSK9X No results 1784 JY8QFUQ01DTS0X No results 1785 JY8QFUQ01B2SD9 No results 1786 JY8QFUQ01DITLY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1787 JY8QFUQ01CUUSO unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1788 JY8QFUQ01ARL85 No results 1789 JY8QFUQ01DCNFO productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 993 96.26 206/214 nt 94.86 203/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-12*01 F 3 8 8 19 8.8.19 [0.17.38.11] CAREVSGYDLTVAGWWGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tggaggcaccttcagcagctatgctatcagctgggtgcgacaggcccctggacaagggcttgagtggatgggaGgggatcatAccctatgtttggaaaaTccaaactacgcacagaagttccagggcagagtcacgataaccgcggacaagtccacgaacacagcctacttggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgagagaagttagtggctacgatttaacagtcgcggggtggtggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1790 JY8QFUQ01BW0AI No results 1791 JY8QFUQ01B3BDQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 670 78.7 170/216 nt 78.24 169/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (78,70% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1792 JY8QFUQ01DJTPF productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1793 JY8QFUQ01A7FYC No results 1794 JY8QFUQ01C0WGL No results 1795 JY8QFUQ01CTYO2 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 373 64.56 133/206 nt 64.08 132/206 nt 8 7 X 8.7.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (64,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1796 JY8QFUQ01DPDG7 No results 1797 JY8QFUQ01BBPY9 unproductive (see comment) Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1798 JY8QFUQ01CGCZI No results 1799 JY8QFUQ01B2VBD No results 1800 JY8QFUQ01AV9ZT No results 1801 JY8QFUQ01AT1TK unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 254 69.64 78/112 nt 8 8 X 8.8.X [0.17.4.X] null + No rearrangement found Low V-REGION identity (69,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 1802 JY8QFUQ01BJOJ3 No results 1803 JY8QFUQ01CF40R productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1804 JY8QFUQ01AYVPB No results 1805 JY8QFUQ01CD1QI No results 1806 JY8QFUQ01A302F unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 120 53.9 76/141 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1807 JY8QFUQ01AFT4R productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 922 92.13 199/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 74 to 75 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggtcAGtctggtataatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1808 JY8QFUQ01A2D85 No results 1809 JY8QFUQ01BL1DX productive (see comment) Homsap IGHV3-9*01 F 796 85.65 185/216 nt 84.26 182/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.16.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 67 of V-REGION: 3 nucleotides (from position 111 in the user submitted sequence), (do not cause frameshift) agcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaaggcctggagtgggtcgcgggcatcaactggaatcgggCaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1810 JY8QFUQ01BBZV8 No results 1811 JY8QFUQ01B9QST No results 1812 JY8QFUQ01DPAXM No results 1813 JY8QFUQ01C1QLG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 863 89.3 192/215 nt 88.84 191/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaggggcgtggagtggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 1814 JY8QFUQ01AZD08 productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 1815 JY8QFUQ01DQUG3 No results 1816 JY8QFUQ01CGARJ No results 1817 JY8QFUQ01C1OTY unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 173 59.23 77/130 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacaacaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccca 1818 JY8QFUQ01B5IEN No results 1819 JY8QFUQ01DPAHM productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccaggctcttccccca 1820 JY8QFUQ01BITXO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1821 JY8QFUQ01BYKOU No results 1822 JY8QFUQ01ASKRO No results 1823 JY8QFUQ01C2X9R No results 1824 JY8QFUQ01CSYUI No results 1825 JY8QFUQ01AEH3Q No results 1826 JY8QFUQ01AR6WE No results 1827 JY8QFUQ01AF8BR No results 1828 JY8QFUQ01DGHZL No results 1829 JY8QFUQ01A30EO No results 1830 JY8QFUQ01COJ91 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1831 JY8QFUQ01BIXDD No results 1832 JY8QFUQ01C6E9M No results 1833 JY8QFUQ01CJJV5 No results 1834 JY8QFUQ01A8YRJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 782 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [0.17.38.11] CATYGRFSFSPLDYW in-frame + ctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctaagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1835 JY8QFUQ01DEBHG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 1836 JY8QFUQ01DGJ7B No results 1837 JY8QFUQ01BPNLJ No results 1838 JY8QFUQ01CE6TX No results 1839 JY8QFUQ01BZB27 No results 1840 JY8QFUQ01DSD1J No results 1841 JY8QFUQ01A9CF3 No results 1842 JY8QFUQ01BJXL8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcacCctttaacaactacgccatgtcctgggtccgccaggctccagggaAaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1843 JY8QFUQ01BOVNW No results 1844 JY8QFUQ01CS04S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1845 JY8QFUQ01C6JP8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1846 JY8QFUQ01DHBAE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 747 82.49 179/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1847 JY8QFUQ01DJQS6 productive (see comment) Homsap IGHV3-72*01 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 10 9 8.10.9 [0.17.38.11] CAVAGPPYDGW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); ctggattcaccttaagtgacttctacatggGactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcaggccccccttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1848 JY8QFUQ01ASZ4D No results 1849 JY8QFUQ01DV61W No results 1850 JY8QFUQ01AZTRZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1851 JY8QFUQ01BMEV3 No results 1852 JY8QFUQ01DBVHS No results 1853 JY8QFUQ01AS5AX No results 1854 JY8QFUQ01AP1CY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.16.38.11] CVSDLAGQKGF# out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1855 JY8QFUQ01CY3DA No results 1856 JY8QFUQ01AKAUZ No results 1857 JY8QFUQ01DV9ZH No results 1858 JY8QFUQ01BQI0I No results 1859 JY8QFUQ01CRM8S unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 684 79.72 173/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 1860 JY8QFUQ01B5RFY No results 1861 JY8QFUQ01AVBNZ No results 1862 JY8QFUQ01A1HYP No results 1863 JY8QFUQ01DATML unknown (see comment) Homsap IGHV4-30-2*01 F, or Homsap IGHV4-30-2*02 F or Homsap IGHV4-30-2*03 F or Homsap IGHV4-30-2*05 F or Homsap IGHV4-30-2*06 F 103 70.45 31/44 nt 68.18 30/44 nt X X X X.X.X [14.X.X.X] null + No rearrangement found stop codons in FR1-IMGT, from codon 7 of V-REGION: 6 nucleotides (from position 126 in the user submitted sequence), (do not cause frameshift) ggggaagaagccctggaccaggcatgcgacgaccacgttcccatcttgggggtgctgtcgaggctcagcgggaagaccttggggctggtcggggatgctggggctggcggatgcagttccaggagtaaccactgaaggacccaccacagac 1864 JY8QFUQ01B2MWG No results 1865 JY8QFUQ01DR09H unknown (see comment) Homsap IGHV4-61*02 F 865 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 9 7 X 9.7.X [1.17.37.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcagtagtggttttactactggagctggacccggcagcccgccgggaagggactggagtggattgggcgtgtccatagcggtggtagttccgactacaaccctccctcacgggtcgagtcaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgtgtatttctgtgcgagagaagcgcctgcctggtccagggcttcttccccca 1866 JY8QFUQ01CLYWH No results 1867 JY8QFUQ01BBW0Y No results 1868 JY8QFUQ01C97D9 No results 1869 JY8QFUQ01BHCHY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 476 94.34 100/106 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatact 1870 JY8QFUQ01BJSGI No results 1871 JY8QFUQ01COQXJ No results 1872 JY8QFUQ01AT5DJ unknown (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F 657 87.13 149/171 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found tatctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggagatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctga 1873 JY8QFUQ01ACPKI No results 1874 JY8QFUQ01AJ2E8 No results 1875 JY8QFUQ01AZW0U No results 1876 JY8QFUQ01CYDQN unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 X 9.7.X [1.17.38.11] CARGETDC##YYFDYW out-of-frame + stop codons tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaactgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 1877 JY8QFUQ01A3GDX No results 1878 JY8QFUQ01BFJNO No results 1879 JY8QFUQ01ABNRN No results 1880 JY8QFUQ01A72XQ productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 1881 JY8QFUQ01CY7BO No results 1882 JY8QFUQ01DH3ZN No results 1883 JY8QFUQ01CFKHZ unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1884 JY8QFUQ01A11WE No results 1885 JY8QFUQ01C5HZ1 productive (see comment) Homsap IGHV4-61*05 F (see comment) 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDQRGRFGTSSTFDYW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01C5HZ1 ; 10 AA in Homsap_IGHV4-61*05) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgtgcgagagatcagcggggccgatttggcacctcgtcaacctttgactactggggccagggagcccaggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 1886 JY8QFUQ01AROJ8 No results 1887 JY8QFUQ01DVTFY productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAREGGRGYDMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcatttatcactgataggggtagtacccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1888 JY8QFUQ01B82PT No results 1889 JY8QFUQ01C8OKU unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 107 53.38 71/133 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1890 JY8QFUQ01C0DF1 No results 1891 JY8QFUQ01CS4AR No results 1892 JY8QFUQ01DC442 No results 1893 JY8QFUQ01A1LA4 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1894 JY8QFUQ01BIHQJ No results 1895 JY8QFUQ01BLL9W No results 1896 JY8QFUQ01ARX0K No results 1897 JY8QFUQ01B7MV6 productive Homsap IGHV1-24*01 F 970 95.31 203/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1898 JY8QFUQ01ADVDL unproductive Homsap IGHV1-2*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDGISMTLVRGVRPFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtAggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaacccctggtcagcgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1899 JY8QFUQ01C9OGI unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ4*03 F (see comment) 19 63.64 7/11 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. gtctggattcaccttcagtacctatggcacacattgggtccgccaggctccaggcaaggggctggactgggtggcagttagttggcatgatggaagtcaggaatattatgcagactccgtgaggggccgattcactgtctccagagacaattccaagaacacggcatatctgcatatgaatgtcctgagaggcgaagacacggctgtctactactgtgtgagagcggcggggtactgtcctgcctggtccagggcttcttcccc 1900 JY8QFUQ01CJTD8 No results 1901 JY8QFUQ01CC49B productive Homsap IGHV3-48*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggatttaccttcagttcttatagtgtcaactgggtccgccaggctccagggaagggcctggagtgggtctcatatattgataatagtggttctaccatatattatgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1902 JY8QFUQ01BJH2P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 1903 JY8QFUQ01APY8H No results 1904 JY8QFUQ01B2IGB unproductive Homsap IGHV3-66*02 F 916 92.49 197/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CSTPTYCRGGSCSQ#FDYW out-of-frame + tctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagattttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 1905 JY8QFUQ01B31PX No results 1906 JY8QFUQ01B0KRM unproductive Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1907 JY8QFUQ01CWAWI No results 1908 JY8QFUQ01CJ7TJ No results 1909 JY8QFUQ01DJ6T7 No results 1910 JY8QFUQ01DWSAC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'CT' (2 nucleotides at position 24 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagcaacCTgactggatgcactgggtccgccaagctccagggaaggggctggGtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 1911 JY8QFUQ01B9JJ8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1912 JY8QFUQ01C5R9N unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 697 80.09 173/216 nt 79.63 172/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found stop codons Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttcccctgaaccggtgacggtgtcgtggaactca 1913 JY8QFUQ01CPPSP unknown (see comment) Homsap IGHV5-10-1*03 F 82 63.83 30/47 nt 61.7 29/47 nt X X X X.X.X [15.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 9 of V-REGION: 2 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggcaaggaccgatgggcccgttcggtggaggtgacgaagccaccagaga 1914 JY8QFUQ01BRFWK No results 1915 JY8QFUQ01AV6NY No results 1916 JY8QFUQ01B3BE0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.16.38.11] CATRNKMGISTPVDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggactcaacattggcaactatgacatgacctgggtccgccaggctcctgggaagggctggagtgggtctcAagatattggaactactgagggtagctcatattatgcGagactccgtgaagggccggttcaccatctccagagacaactcccagactacgctgtttttggagatgagcagcctgagagacgaggacacggccgtatattactgtgcgacaaggaataaaatgggaattagtacgcctgttgactactggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1917 JY8QFUQ01AWJKI No results 1918 JY8QFUQ01CMR9A unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1919 JY8QFUQ01B6DU1 No results 1920 JY8QFUQ01BCEL1 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 81 64.44 29/45 nt X X X X.X.X [15.X.X.X] null + No rearrangement found tgggggaagaagccctggaccaggcatgcgacgaccacgttccatcttgggggtgctggtcgaggctcagcgggaagaccttggggctggtcggggatggcatagg 1921 JY8QFUQ01BHCHA No results 1922 JY8QFUQ01BO45P unknown (see comment) Homsap IGHV3-23*05 F 130 52.51 94/179 nt 8 6 X 8.6.X [1.17.27.X] null - No rearrangement found tctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1923 JY8QFUQ01A8H23 No results 1924 JY8QFUQ01BSOUI No results 1925 JY8QFUQ01DC38A No results 1926 JY8QFUQ01BZ15F No results 1927 JY8QFUQ01BDX2I unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 141 84.62 33/39 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcagcctcacttcctatggcatgaactggg 1928 JY8QFUQ01CLR24 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1929 JY8QFUQ01CXNVM No results 1930 JY8QFUQ01DG57V No results 1931 JY8QFUQ01B5M1X No results 1932 JY8QFUQ01AP4KF productive (see comment) Homsap IGHV3-9*01 F 986 94.95 207/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKSGTYSSSSGHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcaactttaataaGttatgccatgcactggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1933 JY8QFUQ01A32DB No results 1934 JY8QFUQ01BKBQ4 unproductive Homsap IGHV1-18*01 F 880 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD1-1*01 F 2 8 7 X 8.7.X [0.17.38.11] CARVIRTNWL#PL out-of-frame + in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctgggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 1935 JY8QFUQ01DFGBA No results 1936 JY8QFUQ01DPJVA No results 1937 JY8QFUQ01A6727 No results 1938 JY8QFUQ01DII0D unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 799 86.38 184/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CATLRGV#FDYW out-of-frame + tctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggctgacggtgtcgtggaactcag 1939 JY8QFUQ01A6BFE unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYLNS# out-of-frame - in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtacttgaattctgggccagggagccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 1940 JY8QFUQ01CIUY9 No results 1941 JY8QFUQ01BK841 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + tctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1942 JY8QFUQ01BRJJ1 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt 10 9 X 10.9.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatga 1943 JY8QFUQ01A6ZJF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1944 JY8QFUQ01B76V5 No results 1945 JY8QFUQ01DP6RJ No results 1946 JY8QFUQ01BTUJ4 No results 1947 JY8QFUQ01B3HMS No results 1948 JY8QFUQ01C1W9I No results 1949 JY8QFUQ01DFAVE No results 1950 JY8QFUQ01DFETT No results 1951 JY8QFUQ01BAB6B unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 704 81.6 173/212 nt 81.13 172/212 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-7*01 F 1 8 7 X 8.7.X [1.17.37.11] CARLDGHFDL## out-of-frame + Low V-REGION identity (81,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggcccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 1952 JY8QFUQ01DVKOS productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 1953 JY8QFUQ01B74TN unproductive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 408 65.12 140/215 nt 64.65 139/215 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.16.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,12% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggatttacttttaacaacnattggatgacctgggttcgccaggctccagggaagggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1954 JY8QFUQ01ARCKY No results 1955 JY8QFUQ01C6D1R No results 1956 JY8QFUQ01BJTWV productive (see comment) Homsap IGHV3-13*01 F 961 94.84 202/213 nt 94.37 201/213 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.37.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 191 in the user submitted sequence), (cause frameshift) ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccgggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 1957 JY8QFUQ01CQ4P5 No results 1958 JY8QFUQ01CNW3U No results 1959 JY8QFUQ01CZ8KK No results 1960 JY8QFUQ01DSK5G productive (see comment) Homsap IGHV4-39*02 F 853 87.39 194/222 nt 86.04 191/222 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [2.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gtctctggtgaccccatcggcaacagCtgcttactcctggggctggatccgccagTcccccagggaaTggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1961 JY8QFUQ01DM9PX productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1962 JY8QFUQ01CS3SE No results 1963 JY8QFUQ01ARKFZ productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcc 1964 JY8QFUQ01A1QF8 productive (see comment) Homsap IGHV3-9*01 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); ctctggattcGacctttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1965 JY8QFUQ01A57Q0 No results 1966 JY8QFUQ01DGXW2 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARADNYDSLGLKFDP# out-of-frame + tctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1967 JY8QFUQ01DUGCM No results 1968 JY8QFUQ01CW1IT No results 1969 JY8QFUQ01DVF0A unknown (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag 1970 JY8QFUQ01BTR5S No results 1971 JY8QFUQ01BCRE0 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + tctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 1972 JY8QFUQ01B23X3 No results 1973 JY8QFUQ01AT12O No results 1974 JY8QFUQ01C8M0Q productive Homsap IGHV3-NL1*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 8 12 8.8.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame - ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 1975 JY8QFUQ01DNNNP unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 700 91.02 152/167 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DNNNP ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 1976 JY8QFUQ01A62HZ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 934 93.43 199/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CATAPPGPSYSLEYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttatgtttagcggtggtggcacaaactacgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacactgtatcttcaaatgaacagcctgagagccgcggacacggccgtgtattactgtgcgaccgccccaccggggccttcttactcgcttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 1977 JY8QFUQ01BDAGX unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1978 JY8QFUQ01CDNAA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 1979 JY8QFUQ01BGV6Q No results 1980 JY8QFUQ01A35OA No results 1981 JY8QFUQ01ALQ2E No results 1982 JY8QFUQ01B1D65 No results 1983 JY8QFUQ01BWP2N No results 1984 JY8QFUQ01ASV3A No results 1985 JY8QFUQ01AG4US No results 1986 JY8QFUQ01BS3RQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 114 66.67 38/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctctggattcacctttagtaaccattggatggactgggtccagggcttcttccccca 1987 JY8QFUQ01BDQD1 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'TG' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggcgTGgaggtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 1988 JY8QFUQ01DM0QX No results 1989 JY8QFUQ01BQABP No results 1990 JY8QFUQ01BWBEV No results 1991 JY8QFUQ01B6DV5 No results 1992 JY8QFUQ01CBD3F No results 1993 JY8QFUQ01CTQN9 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 1994 JY8QFUQ01CQIDJ No results 1995 JY8QFUQ01CI73V No results 1996 JY8QFUQ01AXXVL No results 1997 JY8QFUQ01DOTOU productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKDHSSGWYYYYGMDVW in-frame + gtctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcatttatacggtatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagatcatagcagtggctggtactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagggagtgcatccgccccaaccct 1998 JY8QFUQ01BLQOD No results 1999 JY8QFUQ01DUO6I No results 2000 JY8QFUQ01BH4OY productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F (see comment) 794 84.62 187/221 nt 84.16 186/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 9 15 8.9.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) tctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 2001 JY8QFUQ01BNCV6 productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2002 JY8QFUQ01A2RVR No results 2003 JY8QFUQ01BG8MK No results 2004 JY8QFUQ01AI06K productive (see comment) Homsap IGHV3-30*01 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAREWAASHFDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) cgctggattcaccttcagtggctttgcttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2005 JY8QFUQ01DDZUD unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDQRDYDYIYYY#GMDLW out-of-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtattatgcagacttcgtgaagggccgattcaccatcaccagggacaattcccagaacactctgtctctgcaattgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacggggatggacctctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 2006 JY8QFUQ01A3LWV unproductive (see comment) Homsap IGHV4-59*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.17.38.11] CARPVLF*YQLLV#FDYW out-of-frame + stop codons ctctggtggccccggcagtagttaggactggacctggatccggcagcccccagggaagggactggagtggattggatatatttattacagtgggagcaccaactacaaccccttcctcaagagtcgagtcaccatatcagtagacacgtccaagaacttgttctccttgaggctgagctctgtgaccgctgcggacacggccatatattactgtgcgagacccgtattgttttagtaccagctgttagtcactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2007 JY8QFUQ01AYO4H No results 2008 JY8QFUQ01CU4N0 No results 2009 JY8QFUQ01CO7MH No results 2010 JY8QFUQ01BKBUH No results 2011 JY8QFUQ01DJWN9 unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 777 85.05 182/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGILR##HFDSW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); tggatacaccttcagcgactactacatacactggctgcgacagGgcccctggacaacgacttgagtggatgggatggctGgaaccctaaTaaatggtgacacagcttatggccagagcttcaagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggcattttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2012 JY8QFUQ01BJ0J7 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 84.62 187/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtgactcCcatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2013 JY8QFUQ01DT1ZM productive (see comment) Homsap IGHV3-33*03 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 7 8 13 7.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) cgtctggattcacctcagtacctatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2014 JY8QFUQ01DG8YX No results 2015 JY8QFUQ01CI1V6 No results 2016 JY8QFUQ01AYX4Y productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2017 JY8QFUQ01B68YS productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame + ctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2018 JY8QFUQ01A2G8U productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2019 JY8QFUQ01DK569 No results 2020 JY8QFUQ01DXFTY No results 2021 JY8QFUQ01A1YTY No results 2022 JY8QFUQ01B6HFK No results 2023 JY8QFUQ01DUD3U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcacttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtatttgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggcccagggagccctggtctccgtctgcctcagcatccccgaccagccccaaggtcttcccgctgaccctcgncagcaccccccaagatgggaacgtggtcgtcgcatgccctggtccaggggcttcttccccca 2024 JY8QFUQ01DEMJX productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1029 98.13 210/214 nt 97.2 208/214 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctgggttcaccgtcagtagcGaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttaCtttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2025 JY8QFUQ01ACURH productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 2026 JY8QFUQ01CTXHU unknown (see comment) Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 89 51.88 69/133 nt 8 10 X 8.10.X [2.17.9.X] null - No rearrangement found stop codons agcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2027 JY8QFUQ01C3TXW No results 2028 JY8QFUQ01B7828 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 8 X 8.8.X [1.16.11.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccgggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 2029 JY8QFUQ01CTQ8T No results 2030 JY8QFUQ01BZ8E5 No results 2031 JY8QFUQ01DS2MQ productive (see comment) Homsap IGHV3-48*03 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ6*02 F (see comment) 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 7 8 14 7.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcgccttcaaaagtttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2032 JY8QFUQ01DLJDT No results 2033 JY8QFUQ01AX4GW No results 2034 JY8QFUQ01CHGVS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 594 75.12 163/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGRSWNHEVEYW in-frame + Low V-REGION identity (75,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacacttaggaattatgatatgaactggatccgccaggctccggggaaggggctagagtgggtctcaagtcttagacttgggtcctatgacacaaattatgcagagtctgtagcgggccggttcgtcgtctccaaagacgaggccagaaacacaatgtttctcctgatgaacgacctgcgagtcgaggacacggccttatattactgtgcgggaaggagttggaatcatgaagttgaatactggggccagggaaccctggtcaccgtctcttcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2035 JY8QFUQ01A6EXK No results 2036 JY8QFUQ01CFUGF No results 2037 JY8QFUQ01BZC7E No results 2038 JY8QFUQ01DSOJF unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 684 94.12 144/153 nt 8 8 X 8.8.X [1.17.16.X] null - No rearrangement found cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacg 2039 JY8QFUQ01DS062 No results 2040 JY8QFUQ01BXYLF productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaatcctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacaacacccccaagtggtcgtcgcatgcctggtccagggcttcttccccca 2041 JY8QFUQ01DR5PE No results 2042 JY8QFUQ01A9S9F No results 2043 JY8QFUQ01AENCQ unproductive (see comment) Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKCQDLFLWFGELFP#FDYW out-of-frame + stop codons ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcaaaatgccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 2044 JY8QFUQ01DFZH3 No results 2045 JY8QFUQ01DMKZ0 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 118 67.86 38/56 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found tctggattcacctttagtaaccattggatgaactgggtccagggcttcttccccca 2046 JY8QFUQ01BFRM4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - tctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagatagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2047 JY8QFUQ01BRNVT No results 2048 JY8QFUQ01AYNGJ productive Homsap IGHV3-NL1*01 F (see comment) 393 78.46 102/130 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 X 5 11 X.5.11 [X.X.38.11] CACGHMRDGYDVW in-frame + Low V-REGION identity (78,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2049 JY8QFUQ01BPXE5 unknown (see comment) Homsap IGHV3-21*04 F (see comment) 733 81.94 177/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcagtagctatagcatgatctgggtccgccaggctccagggaaggggctggagtgggtctcatccattaggagtagttgtacttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2050 JY8QFUQ01BOIQS No results 2051 JY8QFUQ01CE71S No results 2052 JY8QFUQ01AYKXY No results 2053 JY8QFUQ01AKKUX productive (see comment) Homsap IGHV3-7*01 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.37.11] CASGSGWTAEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) tctgaattcaccgttagcagtcattggatgaattgggtccgccaggctccagggaaggggctggaatgggtggccaacataaaacaagatgcaagtgagaaaactatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaattcactgtatctgcaaatgaacagcctgagactcgaggacacggctgtgtatttctgtgcgagtggcagtggctggacagctgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2054 JY8QFUQ01ADWFW No results 2055 JY8QFUQ01A4G76 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 6 16 8.6.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttattatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2056 JY8QFUQ01CD1T0 unknown (see comment) Homsap IGHV3-74*03 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 2057 JY8QFUQ01C6T9J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGDSGIRPIDYW in-frame + cctctggattcacctctagcgcctataccatgagttgggtccgccaggctccagggaaggggctggagtgcgtctcagctattagtggtggtggtactagcacatactacgcagactccgtgaagggccggttcaccatctccagagacacttccaagaacacactgtctctgcacctgaacagcctgagagtcgaggacacggccatatatttctgtgcgaaaggtgattctggtataagacctattgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 2058 JY8QFUQ01DRHHV No results 2059 JY8QFUQ01AV72D unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 1080 100.0 217/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGFPWFGEEYYF*LL# out-of-frame + stop codons ctctggattcacctttgatgattatggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggaatggtggtagcacaggttatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccttgtatcactgtgcgagaggtttcccatggttcggggaggaatactacttttgactactggggccagggtaaccctggtcaccgtctcctcagggagtgcatccgccccaa 2060 JY8QFUQ01B04MT unproductive Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 834 86.82 191/220 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CAHFGPQEHFDFW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttgggggtccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2061 JY8QFUQ01B3HZ7 No results 2062 JY8QFUQ01BI0JQ No results 2063 JY8QFUQ01DVXTX No results 2064 JY8QFUQ01BF1N2 No results 2065 JY8QFUQ01AXU4F unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARLGATRS*LL# out-of-frame + stop codons ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttggggcaactcgctcttgactactgggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2066 JY8QFUQ01AMV8F No results 2067 JY8QFUQ01DVMY3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2068 JY8QFUQ01C389G No results 2069 JY8QFUQ01BI6HV productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGXYYDSGGLDNW in-frame + tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtnattattatgatagtggtggtcttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttccccca 2070 JY8QFUQ01AA3TT No results 2071 JY8QFUQ01A9HTT No results 2072 JY8QFUQ01AIVTV No results 2073 JY8QFUQ01DJPKB No results 2074 JY8QFUQ01DOVP6 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 462 70.77 138/195 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DOVP6 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2075 JY8QFUQ01DRQV8 No results 2076 JY8QFUQ01DIRXR No results 2077 JY8QFUQ01COTM3 No results 2078 JY8QFUQ01BLIBB No results 2079 JY8QFUQ01DE488 No results 2080 JY8QFUQ01DXA71 No results 2081 JY8QFUQ01BWJXL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2082 JY8QFUQ01C3ER5 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 113 55.08 65/118 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found ctctggattcaccttcagtgactactacatgaactggatccgccaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 2083 JY8QFUQ01CT9PI No results 2084 JY8QFUQ01CZFE8 productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CGTSRSLDYW in-frame - ctctggattcacatttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatgggagtgagaaatactatgtcgactctgtgaagggccgattcaccatctccagagacaacgccgagaactcactacatttgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgggacgagcaggtcccttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2085 JY8QFUQ01CCRB7 unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2086 JY8QFUQ01DIV7A productive (see comment) Homsap IGHV1-18*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARENYYTSGIHSGFRHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacatctttaccacctatggtatcagttgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcaacacttacaatggtaacacgaactatggacagaggatccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccgtatattattgtgcgagagaaaactactatacttcgggaattcattccggcttcaggcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2087 JY8QFUQ01BQ1MZ No results 2088 JY8QFUQ01DN3N9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ggcctctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2089 JY8QFUQ01C8KTQ No results 2090 JY8QFUQ01AA6NJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 913 91.67 198/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDHGHCNSGVCMNYGLDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) tctggattcagcttcagtacttatggcatgcactgggtccgccaggctccaggcaaggggctggaatgggtggcaggcacgtcatctgatggcagtcataaataccaggcagactccgtgaagggccgattcaccatctccagagacaactccgagaacacggtgtatctgcaaatgaacagcctgagagttgaggatacggctgtgtattactgtgcgaaagatcatggacattgtaatagtggagtgtgtatgaactacggtttggacgtctggggccaagggaccacggtcaccgtcttcccagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2091 JY8QFUQ01DIQ9W No results 2092 JY8QFUQ01A21H5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARPLSGSSRSPSGYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatggtgatgggactagcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgttgtatttgcaactgagcagtctgagagccgaggacacggctgtgtatttctgtgcaagacccttgagtgggagttccagatcccccagcggctactggggccagggaaccctggtcaccgtctcctccgcatcccgaccagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccccca 2093 JY8QFUQ01AO7GC No results 2094 JY8QFUQ01BAXIB No results 2095 JY8QFUQ01BLHNK No results 2096 JY8QFUQ01BLH9B productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'TG' (2 nucleotides at position 65 to 66 in the user submitted sequence), (cause frameshift); cctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcgTGggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccctctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2097 JY8QFUQ01BDUVW No results 2098 JY8QFUQ01CSKOX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2099 JY8QFUQ01CRX44 No results 2100 JY8QFUQ01BXIPW No results 2101 JY8QFUQ01BIYZO No results 2102 JY8QFUQ01CFUT5 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2103 JY8QFUQ01BCVOY unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 413 80.8 101/125 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame - stop codons Low V-REGION identity (80,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2104 JY8QFUQ01AN9S9 No results 2105 JY8QFUQ01CKNXR No results 2106 JY8QFUQ01BFLW8 No results 2107 JY8QFUQ01DGS48 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 779 83.94 183/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtggaactcag 2108 JY8QFUQ01DJAK2 No results 2109 JY8QFUQ01ACS0O No results 2110 JY8QFUQ01BVLI5 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2111 JY8QFUQ01A8G4W No results 2112 JY8QFUQ01ASMWW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2113 JY8QFUQ01DXHW0 No results 2114 JY8QFUQ01AF1CO No results 2115 JY8QFUQ01BK1E5 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CASFACPGK#GYW out-of-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttgcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2116 JY8QFUQ01AEU7T No results 2117 JY8QFUQ01C1U2A No results 2118 JY8QFUQ01C1NGM No results 2119 JY8QFUQ01BHOKR No results 2120 JY8QFUQ01C3O3B No results 2121 JY8QFUQ01BG6XX unproductive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 392 64.22 140/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (64,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gctacggatttgtcttcagtggcactaatatgaattggctccgccaggctccagggaaggggctggagtggatttcacacattagtcacaatagtgaaaccatattctatgcagactctgtgaggggccgagtcaccatctccagagataaatacaattttgacgactggggccagggaaccctggtcaccgtctcccttgcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2122 JY8QFUQ01DGW16 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2123 JY8QFUQ01A5QNH No results 2124 JY8QFUQ01BUOZE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcaccttcaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 2125 JY8QFUQ01DNIB4 No results 2126 JY8QFUQ01DJ168 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2127 JY8QFUQ01CVAW1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2128 JY8QFUQ01CRPAZ productive Homsap IGHV3-48*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaanatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2129 JY8QFUQ01AR7ZE productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2130 JY8QFUQ01CWBX3 No results 2131 JY8QFUQ01A38VY No results 2132 JY8QFUQ01A2ZSI No results 2133 JY8QFUQ01B6KUR No results 2134 JY8QFUQ01AL7P8 No results 2135 JY8QFUQ01B5HCF unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.12 203/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2136 JY8QFUQ01C2945 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.17.38.11] CARFGPLTRPDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaacctttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2137 JY8QFUQ01DJTI7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CIMDLVGRADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift); cagccnctggattcaactttaacagctttgccatgagctAgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2138 JY8QFUQ01A0EFO unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 700 91.02 152/167 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01A0EFO ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 2139 JY8QFUQ01AHSGI unproductive Homsap IGHV1-69*02 F 813 86.92 186/214 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [0.17.38.11] CATDHPAGVSP#YW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tggggccaccttcaacagttatactttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcatctccacccttggtgtgacaaactacgcgcagaggttccagggcagagtcacgatctccgcggacaagtccacgacgacagcctacatggagttgacaaggctgacatttgaagacacggccgtttattattgtgcgacagatcatcccgcgggcgtcagtccgtgtactggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2140 JY8QFUQ01BEKEH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2141 JY8QFUQ01C2H6O No results 2142 JY8QFUQ01CE5UM productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 347 75.0 96/128 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-16*02 F 3 X 4 11 X.4.11 [X.X.38.11] CARGDLPHYIDYW in-frame + Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacatcttcaccagctacttttatgcactggggcagagtcaccatgaccagcgacacgtccacgaccacagtctacatggagctgagcagcctgagatccgacgacacggccatatattactgtgcgagaggcgatctcccccactacattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2143 JY8QFUQ01DS048 No results 2144 JY8QFUQ01BP2O3 No results 2145 JY8QFUQ01B8PL6 No results 2146 JY8QFUQ01C6EBM No results 2147 JY8QFUQ01BRDLB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2148 JY8QFUQ01CAX4Q productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 2149 JY8QFUQ01DEDQY No results 2150 JY8QFUQ01CYNMU No results 2151 JY8QFUQ01CQRVK productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.16.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggattgggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2152 JY8QFUQ01DK0LQ No results 2153 JY8QFUQ01DPXYW No results 2154 JY8QFUQ01BUOSY productive Homsap IGHV4-34*03 F 881 90.19 193/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CVRNYYDFSGYFNWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtaggtccttcagtggttactactggagttggatccgccagcccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2155 JY8QFUQ01AOEAZ No results 2156 JY8QFUQ01CS6F1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDYYYYGMDVW in-frame + tctggattcacctttagcaactttgccatgagctgggtccgccaggctccagggaagggactggagtgggtctcgactattagtcctagtggtggtaccacatattacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacgctgtatctgcaaatgaacatcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2157 JY8QFUQ01DV5VI No results 2158 JY8QFUQ01CQE4K No results 2159 JY8QFUQ01A5IOF productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2160 JY8QFUQ01BFIN2 No results 2161 JY8QFUQ01DRC1V No results 2162 JY8QFUQ01AUJFT No results 2163 JY8QFUQ01DSE2Q No results 2164 JY8QFUQ01A2RMY No results 2165 JY8QFUQ01CS41F unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD2-21*01 F 2 10 7 X 10.7.X [1.17.37.11] CARGA*YL*Q#PW out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CS41F ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 184 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagcggcagtaccaactactggacctggatccggcagcccccaggaaagggactggaattcattgggtatatctataacagtggcaacaccaactacaacccctccctcaagagccgagtctccatttctttggacaggtccaagaaccagttctccctgaggctgaccccgtgaccgctgcggacacggccatgtattactgtgcgaggggggcatgatacctatgacagcccgtggggccagggaacccgggtcaccgtctcctcggcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2166 JY8QFUQ01ADC3R No results 2167 JY8QFUQ01BBP1D No results 2168 JY8QFUQ01B2S6H No results 2169 JY8QFUQ01BTTXM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 489 83.1 118/142 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 1 X 7 X X.7.X [X.2.38.11] CVSDLAGQKGS# out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BTTXM ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (83,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcaggattcaccttcagtagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtgggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatggaagcgtggtcgtcgcatgcctggtccagggcttcttccccca 2170 JY8QFUQ01ADH67 productive (see comment) Homsap IGHV3-43*01 F, or Homsap IGHV3-9*01 F 332 91.25 73/80 nt 90.0 72/80 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [1.3.14.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 138 nucleotides (from position 39 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttcatgattataccatgcactggatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2171 JY8QFUQ01DS1QC No results 2172 JY8QFUQ01C9X8X unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 96 52.71 68/129 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 2173 JY8QFUQ01DKV9P No results 2174 JY8QFUQ01CSUWR unknown (see comment) Homsap IGHV3-64*03 F, or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 161 57.89 77/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccc 2175 JY8QFUQ01CF034 No results 2176 JY8QFUQ01AJGJC No results 2177 JY8QFUQ01CXTYT No results 2178 JY8QFUQ01DKJE8 No results 2179 JY8QFUQ01DUCDS unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 330 88.24 75/85 nt Homsap IGHJ2*01 F 76 60.38 32/53 nt Homsap IGHD4-17*01 F 3 X X X X.X.X [X.X.28.11] CARLGQLALDY## out-of-frame + caccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggcaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2180 JY8QFUQ01CQ9CQ No results 2181 JY8QFUQ01CBRRR No results 2182 JY8QFUQ01CBWKF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2183 JY8QFUQ01BXJ7S No results 2184 JY8QFUQ01ATV5U No results 2185 JY8QFUQ01AMCBG No results 2186 JY8QFUQ01ATKWD productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2187 JY8QFUQ01A5287 No results 2188 JY8QFUQ01BJD14 No results 2189 JY8QFUQ01DSUH3 No results 2190 JY8QFUQ01CVTAB No results 2191 JY8QFUQ01C989A No results 2192 JY8QFUQ01DP1YW No results 2193 JY8QFUQ01AVAVU No results 2194 JY8QFUQ01C7CV2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDPGNYWGYYYDSW in-frame + ctctggattcacctttagcagttatgccatgagctgggtccgccagactccagggaaggggctggagtggatctcagaaattactggtgatggcgataacatatactacgcagactccgtgaagggccgtttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatccggggaactattgggggtactactatgactcttggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2195 JY8QFUQ01CWN4G unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2196 JY8QFUQ01A1BZT No results 2197 JY8QFUQ01DN2ZY unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2198 JY8QFUQ01CRNHB No results 2199 JY8QFUQ01BOBP5 No results 2200 JY8QFUQ01C2QIG No results 2201 JY8QFUQ01BDLFT No results 2202 JY8QFUQ01CI5VP No results 2203 JY8QFUQ01AW9VS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRQLGFGDLFRFD#PW out-of-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgaccccttggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2204 JY8QFUQ01ATYMV productive (see comment) Homsap IGHV3-74*03 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.16.38.11] CAREDGSGRRHFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagccactggatgcactgggtccgccaaggtatagggaggggctggtgtggcttgcacgtattaacagtgatggcagtagtacagcttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaagacgctttatctgcaaatgaacagtctgagagtcgaggacacggctgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2205 JY8QFUQ01C19UU No results 2206 JY8QFUQ01AOAG7 No results 2207 JY8QFUQ01AV9Y3 No results 2208 JY8QFUQ01DMXUS No results 2209 JY8QFUQ01B0KMP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + tctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2210 JY8QFUQ01AVWI5 No results 2211 JY8QFUQ01C2RY1 No results 2212 JY8QFUQ01AGGEA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.16.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctgatgggtcgttcatgggttacctctggaattggatccgccagccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2213 JY8QFUQ01BFFQA No results 2214 JY8QFUQ01CZINL No results 2215 JY8QFUQ01C9B9C No results 2216 JY8QFUQ01CSZZY productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 849 88.79 190/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRMAAARDGVDIW in-frame + ctctgggttcgccgtcagtagcaagttcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatcctgatgggactacacactatggagactccgtgaggggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggccaaggcacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2217 JY8QFUQ01B0CWS No results 2218 JY8QFUQ01DBFGV No results 2219 JY8QFUQ01A5RHY No results 2220 JY8QFUQ01BI6AD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2221 JY8QFUQ01AWM45 productive Homsap IGHV3-7*01 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + tctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 2222 JY8QFUQ01CZHVS productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 813 85.2 190/223 nt 84.75 189/223 nt Homsap IGHJ5*02 F 110 69.39 34/49 nt Homsap IGHD1-26*01 F 2 8 10 5 8.10.5 [1.17.38.11] CREAIAW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctgggttcgtgttcggtaacttctttatgaattggttccgccagcctccgggaaaggggctggagtgggttggccgcatcaaaaccaaagttgatggtgagacaacagactacgctgcagccgtgaaagacagattcatcatttcaagagatgattcaaaaaatTacgatgtatctgcaaatgaacgacctgaagaccgaggacacggccgtatattattgtcgggaggccatcgcgtggggccagggaaccctggtcaaggtctcatcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2223 JY8QFUQ01DHJ1Z productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2224 JY8QFUQ01BKNX7 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 85 52.0 65/125 nt 8 7 X 8.7.X [1.17.8.X] null - No rearrangement found tctggattcaccttcagtgactactacatgaactggatccgccaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2225 JY8QFUQ01DWYF2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 184 59.7 80/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 2226 JY8QFUQ01DWVJO unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYFEF## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactataacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2227 JY8QFUQ01B0642 No results 2228 JY8QFUQ01A98D6 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg 2229 JY8QFUQ01ATAVU No results 2230 JY8QFUQ01BD3Z5 No results 2231 JY8QFUQ01BTO0L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2232 JY8QFUQ01CF4VF No results 2233 JY8QFUQ01CUWFA unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2234 JY8QFUQ01BX70E No results 2235 JY8QFUQ01CYQUJ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 882 89.86 195/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [2.17.38.11] CARPTYSSGRDAFDTW in-frame - tgtatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2236 JY8QFUQ01CGN24 No results 2237 JY8QFUQ01DNGB1 No results 2238 JY8QFUQ01CGEHA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2239 JY8QFUQ01B7X9B No results 2240 JY8QFUQ01A8RFP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 523 93.28 111/119 nt 8 8 X 8.8.X [1.17.5.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatctattggtagtagtagtagtgacatatactacgcagaccca 2241 JY8QFUQ01CUYWA No results 2242 JY8QFUQ01DKXJ4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 406 89.11 90/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca 2243 JY8QFUQ01BH8AQ unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2244 JY8QFUQ01AQH3D productive (see comment) Homsap IGHV3-7*01 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) tctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatggaagcgtggtcgtcgcatgccctggtccagggcttcttccccc 2245 JY8QFUQ01DN5JE No results 2246 JY8QFUQ01BB93P unproductive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSGFTRR#YW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2247 JY8QFUQ01DW2P7 productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccc 2248 JY8QFUQ01BSP8D unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 425 76.35 113/148 nt 8 7 X 8.7.X [1.17.16.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BSP8D ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactca 2249 JY8QFUQ01CAUAC No results 2250 JY8QFUQ01AFWZL No results 2251 JY8QFUQ01BLQKE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccgtcagcagtggtaattactactggaactggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2252 JY8QFUQ01BS4DR No results 2253 JY8QFUQ01AS7FQ No results 2254 JY8QFUQ01CUTG2 No results 2255 JY8QFUQ01BJKIG No results 2256 JY8QFUQ01DXIMW productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1062 96.9 219/226 nt 96.02 217/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); taccggggacagtgtctctaccaacagagctgcAttggaactggatcaggcagtGccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2257 JY8QFUQ01BUJC8 No results 2258 JY8QFUQ01C57KK No results 2259 JY8QFUQ01A4FOX No results 2260 JY8QFUQ01BQA7E unproductive Homsap IGHV4-61*02 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + tccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2261 JY8QFUQ01ABVZ2 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 118 58.7 54/92 nt 56.52 52/92 nt 8 X X 8.X.X [21.1.X.X] null - No rearrangement found in FR1-IMGT, from codon 14 of V-REGION: 2 nucleotides (from position 100 in the user submitted sequence), (cause frameshift)in FR1-IMGT, from codon 20 of V-REGION: 10 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) gggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttggggctggtcggggatgctgggggctggcggatgcagttccaggagtaaccactgaaggacccaccacaga 2262 JY8QFUQ01C1XGN No results 2263 JY8QFUQ01CYFW8 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF (see comment) 284 69.29 88/127 nt 68.5 87/127 nt 8 8 X 8.8.X [1.16.8.X] null + No rearrangement found Low V-REGION identity (69,29% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaagggctggaatgggtcggtggtgttaattggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2264 JY8QFUQ01CCBHV No results 2265 JY8QFUQ01AU12V No results 2266 JY8QFUQ01AO7RK No results 2267 JY8QFUQ01BID9F unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGS## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagcccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2268 JY8QFUQ01ADMXB unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 146 56.92 74/130 nt 8 6 X 8.6.X [1.17.11.X] null + No rearrangement found tctggattcaactttggcatctataccatggcctgggtccgccaggctccaaggtcttccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2269 JY8QFUQ01AZDDJ unproductive Homsap IGHV1-18*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [0.17.38.11] CARETTILREFIPASG#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacatctttaccacctatggtatcagttgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcaacacttacaatggtaacacgaactatggacagaggatccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccgtatattattgtgcgagagaaactactatacttcgggaattcattccggcttcaggcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2270 JY8QFUQ01CYMX9 unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac 2271 JY8QFUQ01ATJJY No results 2272 JY8QFUQ01CM08J No results 2273 JY8QFUQ01BGHPH unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2274 JY8QFUQ01DVKHO unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc 2275 JY8QFUQ01BACNA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 2276 JY8QFUQ01DW7FA unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2277 JY8QFUQ01AO4GZ No results 2278 JY8QFUQ01BSHN4 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2279 JY8QFUQ01BV06C unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2280 JY8QFUQ01DD56X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2281 JY8QFUQ01C07BL No results 2282 JY8QFUQ01A5997 No results 2283 JY8QFUQ01AH0X0 productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tctctgatgactccgtcagcagtggtcgCttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2284 JY8QFUQ01DSP02 productive Homsap IGHV3-9*01 F 792 85.25 185/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CGRIAKPGLGALDLW in-frame - cgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2285 JY8QFUQ01C92ZP unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F (see comment) 607 75.93 164/216 nt 75.0 162/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [2.17.38.X] null - stop codons no junction found Low V-REGION identity (75,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcaggagttactactggaactCggatccggcagTccccccgggaaggcactgtaatgaagcgagtatatgtcttgcagtgggagcaccaatttaaacccctccctcaagggtctagtcaccatatcaccagacacggccaagaaccagctctccctgaagctgagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2286 JY8QFUQ01DH3KU No results 2287 JY8QFUQ01C3YS3 No results 2288 JY8QFUQ01AVZ2U No results 2289 JY8QFUQ01DWLP4 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 92 52.31 68/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 2290 JY8QFUQ01CRB5W No results 2291 JY8QFUQ01CYYET No results 2292 JY8QFUQ01B123L productive Homsap IGHV3-9*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatcttcagtagctactggatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2293 JY8QFUQ01B0YFD productive (see comment) Homsap IGHV4-39*02 F 951 92.27 203/220 nt 91.82 202/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.16.38.11] CARRYSWNYERFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggaggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatngtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2294 JY8QFUQ01CU4ME productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2295 JY8QFUQ01BIWUQ No results 2296 JY8QFUQ01DW8GO No results 2297 JY8QFUQ01DJ43Y unknown (see comment) Homsap IGHV3-16*01 ORF 93 53.51 61/114 nt 8 X X 8.X.X [25.5.X.X] null + No rearrangement found ctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2298 JY8QFUQ01CBV55 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2299 JY8QFUQ01BO7J4 No results 2300 JY8QFUQ01A1P0U No results 2301 JY8QFUQ01DFCJZ No results 2302 JY8QFUQ01BUO0C productive (see comment) Homsap IGHV1-3*01 F 961 94.84 202/213 nt 94.37 201/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 7 9 8.7.9 [0.17.38.11] CARWNNDLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2303 JY8QFUQ01DWACQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 412 88.46 92/104 nt 87.5 91/104 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 2304 JY8QFUQ01C7TE5 productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2305 JY8QFUQ01BBS32 No results 2306 JY8QFUQ01BE96R productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F (see comment) 731 81.45 180/221 nt 81.0 179/221 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CASGPHGWYHFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctctgggggTcgccgtcaccaccggttcctactactggacctggatccggcagcccccagggaagggactggagtggattggggatttctcctttactggggacaccaaagaaaactcctccctcaggagtcgagtcaccttatcaatagacaggatcaacaatcaggtctccctgcaattaaagtctgtgaccactgcggactcggccatgtatttctgtgcgagcggtccccatggctggtaccactttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2307 JY8QFUQ01BBCFP No results 2308 JY8QFUQ01CTLWV No results 2309 JY8QFUQ01BMIUM No results 2310 JY8QFUQ01DV17G No results 2311 JY8QFUQ01BZ5MM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 97 of V-REGION: 'C' (1 nucleotides at position 196 to 196 in the user submitted sequence), (cause frameshift); ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaCggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 2312 JY8QFUQ01AER7A unproductive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGGGGVHDY# out-of-frame - ctctggattcacctttagtgactattacatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagccagatggaagtcagaaaaactatgtggactctgtgaagggccgattctccatctccagagacaacgccaagaactcactatatctgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgcgagagggggaggaggtgttcacgactattgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2313 JY8QFUQ01AXJ5N No results 2314 JY8QFUQ01A6T0C No results 2315 JY8QFUQ01CUWCS unproductive Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFTRR#YW out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); gctctggaGttcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2316 JY8QFUQ01A04I5 No results 2317 JY8QFUQ01C8C69 unproductive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 10 7 X 10.7.X [1.17.38.11] CATVRAG#AFDIW out-of-frame - stop codons tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtgcgcgccgggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2318 JY8QFUQ01CY2J0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2319 JY8QFUQ01A992X No results 2320 JY8QFUQ01DNZGU No results 2321 JY8QFUQ01CGAAX unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 125 54.89 73/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2322 JY8QFUQ01CLP1Z No results 2323 JY8QFUQ01BQV1A No results 2324 JY8QFUQ01BKVCM No results 2325 JY8QFUQ01CY3HZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgccctggtccagggcttcttcccccgag 2326 JY8QFUQ01C1R7I productive (see comment) Homsap IGHV3-11*01 F 929 93.4 198/212 nt 92.92 197/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [0.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2327 JY8QFUQ01DQ243 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 264 59.49 116/195 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (59,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2328 JY8QFUQ01A0DCZ No results 2329 JY8QFUQ01BQM1M No results 2330 JY8QFUQ01DQXMN unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 2331 JY8QFUQ01A0LBC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgagaacgtggctcatcgcctgcctggtccagggcttnttccccc 2332 JY8QFUQ01BMTSW productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.16.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) tctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggagggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 2333 JY8QFUQ01BQB6I No results 2334 JY8QFUQ01AJEE9 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 2 8 7 16 8.7.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - gcctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtattacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2335 JY8QFUQ01CQWZY No results 2336 JY8QFUQ01A02HL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - gctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2337 JY8QFUQ01AVELH No results 2338 JY8QFUQ01C3RMW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2339 JY8QFUQ01CTDSS No results 2340 JY8QFUQ01CEGUK No results 2341 JY8QFUQ01AY1M4 No results 2342 JY8QFUQ01DVCNS No results 2343 JY8QFUQ01BR1UG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 808 86.85 185/213 nt 85.45 182/213 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 7 17 8.7.17 [1.16.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 2 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggagtggtctcacacgtaatatggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2344 JY8QFUQ01BCK56 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*01 F 398 91.58 87/95 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 X X 16 X.X.16 [X.X.31.11] CAKDELPWDTIEYYFDYW in-frame - cctctggattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2345 JY8QFUQ01B5CFK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 129 55.3 73/132 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaacgtcagtggatactggatgcactgggtccgccaagtgccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2346 JY8QFUQ01CC6VD No results 2347 JY8QFUQ01CSA21 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 2348 JY8QFUQ01ACBHD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTTRPRGWEPLGLDYW in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtaccacacggccccgggggtgggaaccacttggccttgactactggggcctggaaccctgggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2349 JY8QFUQ01ACXS7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggaAGgtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2350 JY8QFUQ01DSULQ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 708 81.99 173/211 nt Homsap IGHJ3*01 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-3*02 F 1 7 8 X 7.8.X [X.17.38.11] CARIWDSWSGAFD#VG out-of-frame + Low V-REGION identity (81,99% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) attcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtgggggccaagggcacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2351 JY8QFUQ01AYSZW No results 2352 JY8QFUQ01AE6X4 productive (see comment) Homsap IGHV3-11*01 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccaGtttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2353 JY8QFUQ01C3FN6 productive (see comment) Homsap IGHV3-7*01 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); cctctggattcaccttGcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2354 JY8QFUQ01BWWEL unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKVRGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 93 of V-REGION: 'G' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggacGagactgagccccgaggacacggccgtctactactgtgcgagagaaaaggttcggggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2355 JY8QFUQ01DTPZS No results 2356 JY8QFUQ01DEPOD unknown (see comment) Homsap IGHV4-61*02 F (see comment) 253 82.43 61/74 nt 10 X X 10.X.X [1.13.X.X] null - No rearrangement found Low V-REGION identity (82,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgcctggatccggcagccca 2357 JY8QFUQ01BQYHT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2358 JY8QFUQ01CB5R8 No results 2359 JY8QFUQ01ANI3M No results 2360 JY8QFUQ01AFJBJ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + ttctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactactttcccgaaccggtgacggtgtcgtggaactc 2361 JY8QFUQ01A9PVH No results 2362 JY8QFUQ01ANG04 productive (see comment) Homsap IGHV3-7*01 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 7 8 8 7.8.8 [1.17.38.11] CARATNADVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) tctggattcacctttaggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2363 JY8QFUQ01COQPL No results 2364 JY8QFUQ01C2OA9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2365 JY8QFUQ01B70GQ No results 2366 JY8QFUQ01BPY1E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 2367 JY8QFUQ01A250U No results 2368 JY8QFUQ01DOI0C No results 2369 JY8QFUQ01C3REN No results 2370 JY8QFUQ01B7MB6 No results 2371 JY8QFUQ01AR75U No results 2372 JY8QFUQ01CXR6M unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 2373 JY8QFUQ01BA8HP unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 994 95.83 207/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGLPIVVVV#CYDPW out-of-frame + tctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccagggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2374 JY8QFUQ01AZPH8 No results 2375 JY8QFUQ01C3E97 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVRHTAMERGDYW in-frame + ttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggcccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2376 JY8QFUQ01DUOQ1 unproductive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2377 JY8QFUQ01CRV4E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 149 89.19 33/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacgtttggcatctatgccatgagttgg 2378 JY8QFUQ01DSPAX unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CAEIGWDKWKC#NWFDPW out-of-frame - tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcggagatcggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgggtcatcgcctgctcgtgccaggcgttcttccccc 2379 JY8QFUQ01B3I35 No results 2380 JY8QFUQ01B036X productive Homsap IGHV4-61*03 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + ccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2381 JY8QFUQ01CUFT2 productive Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*03 F or Homsap IGHV3-71*01 P 165 68.35 54/79 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 X X 19 X.X.19 [X.X.26.11] CATDGVGSTVKLMVMGPFDFR in-frame + ctctggattcgtctttaacaactatgccatgggctggatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2382 JY8QFUQ01BKL42 No results 2383 JY8QFUQ01CZX48 No results 2384 JY8QFUQ01BRMKY No results 2385 JY8QFUQ01B5BK5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 492 84.06 116/138 nt 83.33 115/138 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca 2386 JY8QFUQ01BT391 No results 2387 JY8QFUQ01AUAML productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcgcatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2388 JY8QFUQ01CFLZL productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 2389 JY8QFUQ01BPI88 productive Homsap IGHV3-72*01 F 912 90.13 201/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGYDYW in-frame + ctctggattcatcttcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagagttgcatctaacatttacgccacagaatacgccgcgtctttcaaaggcagattcgtcatctcaagagacaattcaaggaactcattgtttctccaaatgaacagcctgaaaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccc 2390 JY8QFUQ01A10H4 productive Homsap IGHV3-23*02 F (see comment) 220 75.31 61/81 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 X X 16 X.X.16 [X.X.27.11] CAKDRYPRSTAITAPDYW in-frame + Low V-REGION identity (75,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcccctttagcaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2391 JY8QFUQ01C4V3B No results 2392 JY8QFUQ01BLI3J No results 2393 JY8QFUQ01BE1BT No results 2394 JY8QFUQ01AP137 No results 2395 JY8QFUQ01BJ0UN productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERGTSIGGAREFDSW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01BJ0UN ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'AGAACATCTCTTCAATCCCTCCCTCAGGAGTC' (32 nucleotides at position 99 to 130 in the user submitted sequence), (cause frameshift); ttctggtggcgccatcagcgatattggctccttctggagctgggtccgacagcccgccgggagttcgctggagtacatcggacgtgtctataatagtgAGAACATCTCTTCAATCCCTCCCTCAGGAGTCgaatcaccaactacaatcctgccctaaggagtcgagtcaccatgtcagtggacacgtccaagaaccaattttacttgaggttggggtctgtgaccgccgacgacacagccgtctattactgtgcgagagagcgtggtacttcgatcggcggagcgagagaatttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2396 JY8QFUQ01CP4FS unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2397 JY8QFUQ01DMWVA No results 2398 JY8QFUQ01BLE7I No results 2399 JY8QFUQ01DV5WU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2400 JY8QFUQ01A6HGP productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccaggcttcttccccca 2401 JY8QFUQ01DWTJW No results 2402 JY8QFUQ01DCD47 No results 2403 JY8QFUQ01DCID1 No results 2404 JY8QFUQ01DSY8S No results 2405 JY8QFUQ01BDK6D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccc 2406 JY8QFUQ01DOC37 unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 882 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.16.38.11] CVVSSGWLFHY# out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaagggctggagtgggtggccaacataaagcaagacggaagtgagGaaaacctttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactgggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2407 JY8QFUQ01BYXJU productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcgtgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2408 JY8QFUQ01DJLW5 productive Homsap IGHV3-11*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDDSCSGGSCYEYW in-frame - acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2409 JY8QFUQ01CAMWW No results 2410 JY8QFUQ01DV2EL unproductive (see comment) Homsap IGHV3-48*02 F 123 59.57 56/94 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 X X 12 X.X.12 [X.X.31.11] CAGSGRDPYGINVW in-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcaccttcaattcctataccatgatgtgggtcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2411 JY8QFUQ01C028P No results 2412 JY8QFUQ01A8UWT No results 2413 JY8QFUQ01AXKJM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 535 71.76 155/216 nt Homsap IGHJ1*01 F (see comment) 22 75.0 6/8 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (71,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcacccccaacgatggaagcgtggtcgtcgcatgcctggtccagggcttcttccccc 2414 JY8QFUQ01B3ST5 No results 2415 JY8QFUQ01B6YGS unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 2416 JY8QFUQ01A80C2 No results 2417 JY8QFUQ01B020G productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2418 JY8QFUQ01CTP63 No results 2419 JY8QFUQ01B569F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDYW in-frame + tctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 2420 JY8QFUQ01BK4RL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2421 JY8QFUQ01BD3L3 No results 2422 JY8QFUQ01DR0DH productive Homsap IGHV3-66*02 F (see comment) 754 84.04 179/213 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame + Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2423 JY8QFUQ01AVUJJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2424 JY8QFUQ01BR14I No results 2425 JY8QFUQ01C1L00 No results 2426 JY8QFUQ01CCR5Z unproductive (see comment) Homsap IGHV1-2*02 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [0.17.38.11] CARRVPPGDLW##VFDIW out-of-frame + stop codons in FR3-IMGT at codon 95 of V-REGION: 'C' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); tggatacaccttcaacgcctactacatacactgggtgcgacaggtccctggacaagggcttgaatggatgggatacgtcaaccccagtcgtggtggcacaaactatgcacagacgtttcagggcagggtcaccttgaccagggacatgtccatcaacacagtctacttggagttgaacgggctgCaagtctaacgacacggccatttattactgtgcgaggagggtcccccctggggatctctggttatgtttttgatatctggggccaagggacacaggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2427 JY8QFUQ01DGJRC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame + ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 2428 JY8QFUQ01DUWRL productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 1073 98.64 218/221 nt 97.74 216/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 1 7 10 11 7.10.11 [1.17.38.11] CTPWWRGGYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctggattcacctctgtgattatgctatgagctggctccgccaggctccagggaaggggctggagtgggtaggAtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaaccatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccccgtggtggcggggaggttactttgactactggggccagggaaccccggtcaccgtgtccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2429 JY8QFUQ01DS7VP unproductive (see comment) Homsap IGHV3-48*01 F 855 88.48 192/217 nt 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcttcagtttgagtacttataccatgGaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2430 JY8QFUQ01BQ23L No results 2431 JY8QFUQ01C53RL No results 2432 JY8QFUQ01BT5A6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'GTC' (3 nucleotides at position 72 to 74 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggGTCagtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2433 JY8QFUQ01AJJ2J No results 2434 JY8QFUQ01CP1R5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 951 92.73 204/220 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-21*01 F 2 8 8 27 8.8.27 [2.17.38.11] CARARGGPPAEYCNDGRCRPVGTAALDIW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgaagacacggctgtctattattgtgcaagagcacgaggggggcctcccgcagaatattgtaatgatggaagatgccgccccgttggaacggcggcccttgatatctggggccaagggacaatggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2435 JY8QFUQ01DNUH4 No results 2436 JY8QFUQ01CEC3V productive Homsap IGHV1-18*01 F 921 92.52 198/214 nt Homsap IGHJ6*01 F 117 65.08 41/63 nt 8 8 16 8.8.16 [0.17.38.11] CARDYIQNYYYYVMWTRH (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION tggttacacctttagcaactatggtctcagctgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaatccttactatggtaacacagattatgcacagaaattccaggacagaatcaccatgaccacagacacatccacgggcacagcctacttggagttgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagactatatccaaaactactactactacgtgatgtggactcggcatgggcaaggcaccgacgtcaccgtctcctcagcattcccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2437 JY8QFUQ01BMUYA unproductive Homsap IGHV3-72*01 F 1078 98.65 219/222 nt 98.2 218/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.16.38.11] CLRPPRYD#PG out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2438 JY8QFUQ01AV39T No results 2439 JY8QFUQ01B33NP No results 2440 JY8QFUQ01C26RM No results 2441 JY8QFUQ01DT048 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + gtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 2442 JY8QFUQ01CBOEK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 7 10 8.7.10 [1.17.38.11] CAREVSDALDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 2443 JY8QFUQ01DT5ZE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 7 8 12 7.8.12 [2.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gcctctacattcgccttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2444 JY8QFUQ01CD3AP No results 2445 JY8QFUQ01DVY06 No results 2446 JY8QFUQ01CXH8O unknown (see comment) Homsap IGHV5-51*05 F 149 56.62 77/136 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found gttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2447 JY8QFUQ01AXPVH No results 2448 JY8QFUQ01DA70A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctcggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2449 JY8QFUQ01A2I1Q No results 2450 JY8QFUQ01A4DX4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 817 87.32 186/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 2 7 8 X 7.8.X [0.17.38.11] CAKVYTGASGGS*#FDSW out-of-frame - stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tggattcagcttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtacatttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctcggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2451 JY8QFUQ01BB7SG No results 2452 JY8QFUQ01A3I1N productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARRPAAGSHFALDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ttctggatacaactttgacaccgattggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgctgactctgataccagatacagtccgtccttccaaggccaagtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcggcctgaaggcctcggacaccgccatctattattgtgcgaggcgtccagcagctggtagccacttcgctttggacgtctggggccaggggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 2453 JY8QFUQ01BHA2N unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 845 87.91 189/215 nt 87.44 188/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2454 JY8QFUQ01DSMOW No results 2455 JY8QFUQ01A868D unproductive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 930 92.99 199/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKGSFDSSGRPEAFDI## out-of-frame + Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggaggcaccttcagtagatatgctttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtccctctctttggttccataaagtacgcacagaagtaccagggcagagccacgattaccgcggacgaatccacgagcacagtctacatggagctgagcagcctgagatctgacgacacggccatgtattactgtgcgaagggttcctttgatagtagtggtcgccctgaggcttttgatatctggggccaagggtacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2456 JY8QFUQ01AT3W2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 942 92.27 203/220 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - agcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2457 JY8QFUQ01C82WJ No results 2458 JY8QFUQ01BAWMT No results 2459 JY8QFUQ01DRHOK productive (see comment) Homsap IGHV3-48*01 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 2460 JY8QFUQ01AY5MA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2461 JY8QFUQ01B4Z6K unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 718 85.64 167/195 nt 84.62 165/195 nt 8 2 X 8.2.X [1.16.36.X] null + No rearrangement found stop codons in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) ctgtggtgggtccttcagtggtttctactagagatgcatccgccagccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgcacggtgtcgtggaactcag 2462 JY8QFUQ01C7IDB unknown (see comment) Homsap IGHV3-74*03 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacaggcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 2463 JY8QFUQ01BBMRP unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 461 70.98 137/193 nt 8 7 X 8.7.X [0.17.31.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BBMRP ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2464 JY8QFUQ01CU1XI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 889 91.08 194/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 6 12 8.6.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 2465 JY8QFUQ01APTCB No results 2466 JY8QFUQ01CMICY No results 2467 JY8QFUQ01AYN2M No results 2468 JY8QFUQ01DDLK7 No results 2469 JY8QFUQ01CCIQV unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 106 53.44 70/131 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 2470 JY8QFUQ01BL5TH unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-16*01 F 1 7 8 X 7.8.X [1.17.38.11] CAREVSDAFEM# out-of-frame + Other possibilities: Homsap_IGHJ3*02 and Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) tctggattcatctttgatgatttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtgggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2471 JY8QFUQ01DBVCU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2472 JY8QFUQ01ATSWA unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ6*01 F 84 62.75 32/51 nt Homsap IGHD6-6*01 F 2 8 10 X 8.10.X [0.16.38.11] CTSNSWLDR# out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) tggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaagggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaaccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 2473 JY8QFUQ01BA14W No results 2474 JY8QFUQ01CPUKD No results 2475 JY8QFUQ01DKCM5 No results 2476 JY8QFUQ01C0T7U unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 116 54.14 72/133 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 2477 JY8QFUQ01ARC7L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2478 JY8QFUQ01CQB35 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CGKPIVGATGREMPVS## out-of-frame + ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggcccagggaaccctggtcaccgtctccgtcagcatcccctgaccagcccctaaggtcttcccgctgagcctctgcagcatccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaat 2479 JY8QFUQ01BZZLJ No results 2480 JY8QFUQ01A622C productive Homsap IGHV3-21*04 F 483 89.26 108/121 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 X 2 10 X.2.10 [X.X.38.11] CARAVSNQVDVW in-frame - ctctggattcgccttcaactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccaggcgttcttccccca 2481 JY8QFUQ01BR57P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacttccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2482 JY8QFUQ01BKRAY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2483 JY8QFUQ01C9QBA productive (see comment) Homsap IGHV1-18*01 F 953 93.95 202/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctggttacaGcctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgGtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 2484 JY8QFUQ01BE5D4 productive (see comment) Homsap IGHV3-23*05 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 7 18 8.7.18 [2.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 2485 JY8QFUQ01AT7WL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 489 83.1 118/142 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 X 7 10 X.7.10 [X.2.38.11] CVSDLAGQKGSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AT7WL ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (83,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcaggattcaccttcagtagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2486 JY8QFUQ01B1545 No results 2487 JY8QFUQ01DUM85 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 2488 JY8QFUQ01AXUND unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 242 82.86 58/70 nt 8 X X 8.X.X [0.15.X.X] null + No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttccccca 2489 JY8QFUQ01BQ5HS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 134 63.29 50/79 nt 8 X X 8.X.X [0.17.X.X] null + No rearrangement found stop codons ctggattcacctttagcagctatgccatgagctgggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca 2490 JY8QFUQ01CL5YX No results 2491 JY8QFUQ01DV6BW No results 2492 JY8QFUQ01DRKBX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaCcctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2493 JY8QFUQ01BX9AL No results 2494 JY8QFUQ01B1UIQ No results 2495 JY8QFUQ01C7DXS No results 2496 JY8QFUQ01DT7MS No results 2497 JY8QFUQ01AFNSC No results 2498 JY8QFUQ01A5Q00 No results 2499 JY8QFUQ01BWSC5 No results 2500 JY8QFUQ01DQ3L4 No results 2501 JY8QFUQ01AXVCU No results 2502 JY8QFUQ01C1FRP No results 2503 JY8QFUQ01CPRDH productive (see comment) Homsap IGHV3-69-1*01 P (see comment) 739 89.62 164/183 nt 88.52 162/183 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 X 8 13 X.8.13 [X.16.38.11] CARGLAVILGGFDYW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01CPRDH ; 7 AA in Homsap_IGHV3-69-1*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift) gagtgggtgccgccaggctccagggaagggctggagtgggtctcagGgcttttgtggaagtgctcctaccacacactacgcagactccgtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag 2504 JY8QFUQ01C7P46 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); tctacattcgcctttagcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2505 JY8QFUQ01AD53G No results 2506 JY8QFUQ01DUC3R unknown (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2507 JY8QFUQ01DTY3N productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 780 84.09 185/220 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame + Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2508 JY8QFUQ01ANCKN No results 2509 JY8QFUQ01BTEGL productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFTYAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gtctggattcacgGttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccacccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2510 JY8QFUQ01BE8LJ No results 2511 JY8QFUQ01B75Q6 No results 2512 JY8QFUQ01DIM6B unproductive Homsap IGHV3-7*03 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.16.38.11] CARDDSCSGGSCYEY# out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaagggctggagtgtgtggccgacataaAagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactgggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2513 JY8QFUQ01AS4PV No results 2514 JY8QFUQ01DTWCT No results 2515 JY8QFUQ01AP23I productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 2516 JY8QFUQ01DQGIC No results 2517 JY8QFUQ01CA0LZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2518 JY8QFUQ01AJKNH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 406 89.11 90/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca 2519 JY8QFUQ01DME78 No results 2520 JY8QFUQ01DBYWE No results 2521 JY8QFUQ01DJTIE unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 146 60.19 62/103 nt 59.22 61/103 nt 8 8 X 8.8.X [0.16.1.X] null + No rearrangement found in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cggttacattgttaccacctctggtttcagctgggtgcgacaggccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2522 JY8QFUQ01DERGA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRDSGPSGYARYESMDVW# out-of-frame + in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggaagGtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggggccaaagggaccgcggtcaccgtctcctcagcctccaccaagggcatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2523 JY8QFUQ01DVV9D No results 2524 JY8QFUQ01DW5H9 productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 2525 JY8QFUQ01DQLUI productive Homsap IGHV3-11*01 F 1071 99.54 216/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*02 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGLSSIPRYNWFDPW in-frame - ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatgggttatcttctataccgcgatacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2526 JY8QFUQ01BMUM8 No results 2527 JY8QFUQ01CHCC5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccaatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2528 JY8QFUQ01CTIK4 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 816 85.91 189/220 nt 85.0 187/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.37.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtactcattactattggggctggatccggcagCcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaacatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcaccctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2529 JY8QFUQ01A4BI4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2530 JY8QFUQ01A9QX6 No results 2531 JY8QFUQ01AI0QW productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F (see comment) 324 84.62 77/91 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 X X 13 X.X.13 [X.X.30.11] CARFSGSYKSAFDIW in-frame + Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctggatacatctttaccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 2532 JY8QFUQ01AUAZ1 No results 2533 JY8QFUQ01DQQ6W No results 2534 JY8QFUQ01DRVXM No results 2535 JY8QFUQ01C1GF6 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcagcctcacttcctatggcatgaactgg 2536 JY8QFUQ01BEHNP No results 2537 JY8QFUQ01BZ8L3 No results 2538 JY8QFUQ01CSHBV No results 2539 JY8QFUQ01BX8J8 No results 2540 JY8QFUQ01AV3PU No results 2541 JY8QFUQ01AXI1X No results 2542 JY8QFUQ01DXAOK No results 2543 JY8QFUQ01AQ5RD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2544 JY8QFUQ01B369H No results 2545 JY8QFUQ01AEVL7 No results 2546 JY8QFUQ01DNI65 No results 2547 JY8QFUQ01B5XWQ No results 2548 JY8QFUQ01B5RFD No results 2549 JY8QFUQ01CD6UL No results 2550 JY8QFUQ01AL1NI unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 943 91.89 204/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 10 X 8.10.X [1.17.38.11] CVVDIPEVGVG#FDYW out-of-frame + tctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttggtgtggggaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 2551 JY8QFUQ01AENYV No results 2552 JY8QFUQ01B4RSD No results 2553 JY8QFUQ01DGLU4 No results 2554 JY8QFUQ01A6P6Z productive Homsap IGHV3-64*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcatactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2555 JY8QFUQ01CA3YC No results 2556 JY8QFUQ01DJU9H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaact 2557 JY8QFUQ01DLWTU unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYLNL#DYW out-of-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatatttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2558 JY8QFUQ01DNYHK unknown (see comment) Homsap IGHV1-NL1*01 P 95 57.32 47/82 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagaca 2559 JY8QFUQ01CUV3Y unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 434 77.03 114/148 nt 75.68 112/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (77,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaAcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagAaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca 2560 JY8QFUQ01CQGEM No results 2561 JY8QFUQ01A9PLD productive (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.37.11] CARVNKDSTDMW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaaagGgggctggagtgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgttttgcagatgaacagcctgagaggcgaggacacggctgtgtattcctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 2562 JY8QFUQ01BJCOA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 2563 JY8QFUQ01BXFLY productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga 2564 JY8QFUQ01DJ6AS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 955 93.15 204/219 nt 91.78 201/219 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CAKIIPPMTGVVHYTDY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'GG' (2 nucleotides at position 128 to 129 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttagccactttgccgtgacctgggtccgccaggctccagggaagggtctgGgaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaaGGgggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatattactgtgcgaaaataatcccccctatgacaggagtggtccattataccgactactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2565 JY8QFUQ01BTEHZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggagacgtggtcgtcgcatgcctggtcccaggggcttcttccccca 2566 JY8QFUQ01A053Y No results 2567 JY8QFUQ01B2881 No results 2568 JY8QFUQ01AL0BU No results 2569 JY8QFUQ01DT394 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctca 2570 JY8QFUQ01A7UQW productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2571 JY8QFUQ01AX5SQ No results 2572 JY8QFUQ01CNY4M No results 2573 JY8QFUQ01B10SN unknown (see comment) Homsap IGHV3-33*04 F, or Homsap IGHV3-48*03 F or Homsap IGHV3-62*01 P or Homsap IGHV3-NL1*01 F 91 54.46 55/101 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcacctttagtagttctggcatgtattgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 2574 JY8QFUQ01C2LW8 productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F (see comment) 754 80.95 187/231 nt 79.65 184/231 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-10*01 F 3 8 10 16 8.10.16 [4.17.38.11] CARIWEPSITFLHTFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift); aggggttcgggggctttcacctttggtgaCtgatgctatcagttggttccgccaggctcctgggaAaggggctggagtggattgctctccttaggagcaaaccttataattcaccaacacaattcgccacgtctgtgaaaggccgattcactgtctcaagagatgactcggaaagtgtcgcctatctgcacatgaacAagcctgcaaaccggggacacagccgtgtattattgtgccagaatatgggaaccaagtattactttccttcatacatttgatgtctggggccgagggacacgggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 2575 JY8QFUQ01DCPE5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacGtttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2576 JY8QFUQ01DQN4D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggcactacttccccgaaccggtgacggtgtcgtggaactc 2577 JY8QFUQ01AUCEO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 528 90.0 117/130 nt 89.23 116/130 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 X 12 8.X.12 [1.3.31.11] CVKDISRSGCFEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattccagtttagcaactatgccatgagctggggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2578 JY8QFUQ01BTHDM No results 2579 JY8QFUQ01ATMQR No results 2580 JY8QFUQ01CCTYG productive Homsap IGHV3-7*01 F 940 93.06 201/216 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaatgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2581 JY8QFUQ01DTZBY No results 2582 JY8QFUQ01C70TW No results 2583 JY8QFUQ01DOFMA No results 2584 JY8QFUQ01CXJMK No results 2585 JY8QFUQ01BYHF0 No results 2586 JY8QFUQ01ANQIJ unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 805 85.65 185/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2587 JY8QFUQ01CTKHD No results 2588 JY8QFUQ01AUT05 unknown (see comment) Homsap IGHV3-66*03 F 114 58.06 54/93 nt 8 4 X 8.4.X [1.17.X.X] null - No rearrangement found cctctgggttgaccgtcagtgccgaccacatgtactgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2589 JY8QFUQ01CRUH8 No results 2590 JY8QFUQ01A3VC8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2591 JY8QFUQ01DDAOB unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.38.11] CATYGRFSF#SLDYW out-of-frame + ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctcccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2592 JY8QFUQ01DKDYZ No results 2593 JY8QFUQ01CWD36 No results 2594 JY8QFUQ01CZQ6V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacagtgtcgtggaactcag 2595 JY8QFUQ01BGDUG No results 2596 JY8QFUQ01B1ZYW No results 2597 JY8QFUQ01DJ6HA unproductive Homsap IGHV3-72*01 F 1043 96.43 216/224 nt 94.64 212/224 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 1 8 10 X 8.10.X [1.17.38.11] CVRGLHSNYYGMDVR# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'A' (1 nucleotides at position 172 to 172 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 184 to 184 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggGggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcaActgtatctgcaAaatgaacagcctgaAaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcagggggccaaggggaccacggtcaccgtctcctcagcatcccccgaccagcccccaagggtcttcccgctgagcctcgacagcaccccccaagatggggaaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 2598 JY8QFUQ01DHC7V No results 2599 JY8QFUQ01BAS1J unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CTREVGATDY## out-of-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2600 JY8QFUQ01DSBXN unproductive (see comment) Homsap IGHV3-72*01 F 854 87.05 195/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 10 X 8.10.X [1.17.38.11] CAVAAPPL#DGW out-of-frame + stop codons tctccggattcacctttagtaaatattccatgaactgggtccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccgttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagcccgaaggtcttcccgctgagcctcgacagcaccccccaatgatgggaacgtgtcgtcgcatgcctggtccagggcttcttcccc 2601 JY8QFUQ01BBOEJ No results 2602 JY8QFUQ01B1YYJ No results 2603 JY8QFUQ01BAO50 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [2.17.38.11] CATSRGSANWY#FDHW out-of-frame - gcctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtaccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2604 JY8QFUQ01CFLF8 No results 2605 JY8QFUQ01A0P1M No results 2606 JY8QFUQ01C813I productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2607 JY8QFUQ01B6GS0 No results 2608 JY8QFUQ01B2HC6 No results 2609 JY8QFUQ01BCCIF No results 2610 JY8QFUQ01AURRA No results 2611 JY8QFUQ01C91GZ No results 2612 JY8QFUQ01A92YU No results 2613 JY8QFUQ01B5Q6J productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2614 JY8QFUQ01AGB56 No results 2615 JY8QFUQ01AYDED unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 97 52.14 73/140 nt 10 9 X 10.9.X [1.17.9.X] null - No rearrangement found stop codons tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2616 JY8QFUQ01BO7UV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 942 91.82 202/220 nt 90.91 200/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); agcctctggattcaccttTtagtagttttgGccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2617 JY8QFUQ01DLFYU No results 2618 JY8QFUQ01BB6CS No results 2619 JY8QFUQ01CN4JA unproductive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CAKFGGYWRVEQPHLLF#W out-of-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaatttggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2620 JY8QFUQ01AK0R9 unproductive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CLAEVGGRQFDN## out-of-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccaggggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2621 JY8QFUQ01BM964 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-9*01 F or Homsap IGHV3-9*03 F 162 73.02 46/63 nt 71.43 45/63 nt 8 X X 8.X.X [1.11.X.X] null + No rearrangement found in FR2-IMGT at codon 43 of V-REGION: 'CGC' (3 nucleotides at position 41 to 43 in the user submitted sequence), (do not cause frameshift); ctctggattccggtttgatgattatgccatacattgggttCGCctgcctggtccagggcttcttcc 2622 JY8QFUQ01AWITC No results 2623 JY8QFUQ01C0CP5 No results 2624 JY8QFUQ01AWXRB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2625 JY8QFUQ01BK4WK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2626 JY8QFUQ01DHPUK productive (see comment) Homsap IGHV4-34*06 F (see comment) 681 80.48 169/210 nt 79.05 166/210 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 7 7 14 7.7.14 [1.16.38.11] CSRGGQSAGWHSFEAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 26 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) tccatggtgggtccctcagggttaccctggactggatccgccacaccgcagagaagggactggagtgattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2627 JY8QFUQ01DTUPK No results 2628 JY8QFUQ01ASS7S No results 2629 JY8QFUQ01BCXZR No results 2630 JY8QFUQ01CAZ6G No results 2631 JY8QFUQ01A4GLP unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F or Homsap IGHV3-30*03 F 91 95.0 19/20 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcaccttcatta 2632 JY8QFUQ01DF84X productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTREWSGIDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 2633 JY8QFUQ01DTGG9 productive (see comment) Homsap IGHV4-61*07 F (see comment) 766 83.56 183/219 nt 82.65 181/219 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); gtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactGgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctcCcctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggctcatcggtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2634 JY8QFUQ01DMF6C No results 2635 JY8QFUQ01DFMJ0 No results 2636 JY8QFUQ01AGCI5 No results 2637 JY8QFUQ01DUWP8 No results 2638 JY8QFUQ01B5XDP unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 138 64.1 50/78 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 2639 JY8QFUQ01A7KJZ productive (see comment) Homsap IGHV3-7*01 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDPYKPGSGNPGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); agcctctggaGttcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2640 JY8QFUQ01BJTTM unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.16.38.11] CAKGVVTATLTT## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaagggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2641 JY8QFUQ01DCFZ0 No results 2642 JY8QFUQ01BF83J unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F (see comment) 366 67.82 118/174 nt 8 10 X 8.10.X [1.17.21.X] null - No rearrangement found Low V-REGION identity (67,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2643 JY8QFUQ01DOIT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc 2644 JY8QFUQ01DPYJO No results 2645 JY8QFUQ01CIJUJ No results 2646 JY8QFUQ01ATNFH No results 2647 JY8QFUQ01C4NTG No results 2648 JY8QFUQ01C2I90 No results 2649 JY8QFUQ01DXF41 productive (see comment) Homsap IGHV3-7*01 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.37.11] CAISSGYYSTGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 78 of V-REGION: 1 nucleotides (from position 138 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccactccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2650 JY8QFUQ01BY9AG productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame + tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 2651 JY8QFUQ01BG6CL No results 2652 JY8QFUQ01C062K No results 2653 JY8QFUQ01AS67A No results 2654 JY8QFUQ01B1X0K No results 2655 JY8QFUQ01CUV81 No results 2656 JY8QFUQ01CJ8FQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2657 JY8QFUQ01BFUYH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2658 JY8QFUQ01BNOH6 No results 2659 JY8QFUQ01CYL1O No results 2660 JY8QFUQ01AVGL3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 20 8.8.20 [1.17.38.11] CAKAAYYYGSGSISSSTHFDYW in-frame + tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagccgcgtattactatggttcggggagtatcagttcctctacccactttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc 2661 JY8QFUQ01BMHAR unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 101 53.08 69/130 nt 8 6 X 8.6.X [1.17.10.X] null + No rearrangement found cctctggattcatcttcagtagctactggatgcactgggtccgccaagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 2662 JY8QFUQ01DESM8 No results 2663 JY8QFUQ01BJPBW No results 2664 JY8QFUQ01DLJH0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2665 JY8QFUQ01C1KS5 No results 2666 JY8QFUQ01BDWKJ No results 2667 JY8QFUQ01DQW9S No results 2668 JY8QFUQ01ABSTL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatcatgcaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2669 JY8QFUQ01APACT productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 393 91.49 86/94 nt 90.43 85/94 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2670 JY8QFUQ01BI2SK unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 161 53.17 109/205 nt 8 8 X 8.8.X [1.17.34.X] null + No rearrangement found stop codons ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2671 JY8QFUQ01ABL1C unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 481 68.98 149/216 nt 68.52 148/216 nt Homsap IGHJ1*01 F (see comment) 27 77.78 7/9 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (68,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift); tctggatttacctttacaaattattggatgagctgggtccgccaggctccagggaggggcgtggaGAgtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2672 JY8QFUQ01AD0NY productive (see comment) Homsap IGHV4-61*08 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 11 10.7.11 [1.17.37.11] CARGRDAYKVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) tctggtgactccgccagcagtggtgattcgtactggagctggatccggcagcccccagggaagggactggagtggattggatatatctataagagtggggacaccgattataacccctccctcaggagtcgagtcaccatatcagtggacacgtccaagacccagtttccctgaagctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggaagagatgcctacaaggtgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2673 JY8QFUQ01BK12H No results 2674 JY8QFUQ01BY9V7 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*03 F 828 88.94 185/208 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 6 8 21 6.8.21 [X.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2675 JY8QFUQ01CJ2BM No results 2676 JY8QFUQ01BRMG1 No results 2677 JY8QFUQ01BNM74 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 137 55.4 77/139 nt 10 7 X 10.7.X [1.17.10.X] null - No rearrangement found tctctggtggctccatcagcagtagtagttactactggggctggatccgccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2678 JY8QFUQ01BIWCY No results 2679 JY8QFUQ01BU16O productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [2.16.38.11] CAKDGPGGGWYAEQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) gcgtctggattcagtttcagtgactatggcatgcactgggtccgccagactccaggcaaggggctggagtggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2680 JY8QFUQ01DPH29 No results 2681 JY8QFUQ01BXM5S unknown (see comment) Homsap IGHV2-26*01 F, or Homsap IGHV2-5*01 F or Homsap IGHV2-5*02 F or Homsap IGHV2-5*03 F or Homsap IGHV2-5*04 F or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F or Homsap IGHV2-70*09 ORF or Homsap IGHV2-70*12 F 50 100.0 10/10 nt X X X X.X.X [3.X.X.X] null + No rearrangement found accctcacgc 2682 JY8QFUQ01BL8LZ No results 2683 JY8QFUQ01CYWI2 No results 2684 JY8QFUQ01BYMDC No results 2685 JY8QFUQ01CEK8F unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 106 53.44 70/131 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 2686 JY8QFUQ01ACUD8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 361 88.17 82/93 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 1 X X X X.X.X [X.X.31.11] CANWLSGHILSLTT# out-of-frame + tctggattcaccttcagcaaagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcgggacacattctaagtttgactactgggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 2687 JY8QFUQ01CCFND unknown (see comment) Homsap IGHV4-61*02 F (see comment) 712 80.82 177/219 nt 10 7 X 10.7.X [2.17.37.X] null - No rearrangement found Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2688 JY8QFUQ01A5VSB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2689 JY8QFUQ01DFS3F productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 733 82.41 178/216 nt 81.02 175/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GAG' (3 nucleotides at position 83 to 85 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) ctcagggttcgttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattgGAGgtgttgatgatgttggcacatactacgcagcctccgtgaAagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2690 JY8QFUQ01BE5CI No results 2691 JY8QFUQ01A8RAK unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 102 91.67 22/24 nt 7 X X 7.X.X [0.X.X.X] null + No rearrangement found tccgggacagtgtctctagcaaca 2692 JY8QFUQ01AUQRD No results 2693 JY8QFUQ01A2OX9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 792 85.25 185/217 nt 84.33 183/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); ctctgaattcagtttcactgaccaccacatgagctgggtccgccaagctccaggcaaGggggctggtgtgggtctcaCgcattaaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcactccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2694 JY8QFUQ01C3F7Z No results 2695 JY8QFUQ01BAA94 unproductive (see comment) Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVGSDA##FDVW out-of-frame + stop codons ctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagttgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2696 JY8QFUQ01DW16O No results 2697 JY8QFUQ01A7HLN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2698 JY8QFUQ01A4ZVI No results 2699 JY8QFUQ01B7LRA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 844 86.94 193/222 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTWDSTGYFRLTW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2700 JY8QFUQ01CTU0J No results 2701 JY8QFUQ01BH8NM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 2702 JY8QFUQ01BU9Y0 No results 2703 JY8QFUQ01BW717 No results 2704 JY8QFUQ01AZEHJ No results 2705 JY8QFUQ01DK8X9 No results 2706 JY8QFUQ01B6N08 No results 2707 JY8QFUQ01A9VOL No results 2708 JY8QFUQ01BD45K No results 2709 JY8QFUQ01BTJRN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2710 JY8QFUQ01DANVN productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2711 JY8QFUQ01DFS2N No results 2712 JY8QFUQ01AORCI productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2713 JY8QFUQ01CKQ8F No results 2714 JY8QFUQ01AF005 No results 2715 JY8QFUQ01B5RIA No results 2716 JY8QFUQ01ASMQO productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 7 8 17 7.8.17 [1.16.38.11] CARDSGSSDYTRYDAQDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctggattcagtttagttcttatggcatgaactgggtccgccaggctccaggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 2717 JY8QFUQ01AJHPY No results 2718 JY8QFUQ01CD6TE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcacctttgatgactatggcatgcactgggtccggcaagctccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2719 JY8QFUQ01CM9UW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [1.17.38.11] CARDLASFCGGDCPIDYW in-frame + ctctggattcacctttggcaagtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtcctagtactggttacacatactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagacgtgaggacacggctgtgtatttctgtgcgagagatctggcatcattttgtggtggtgactgccccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 2720 JY8QFUQ01ARFVX No results 2721 JY8QFUQ01AV7MG unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 2722 JY8QFUQ01CEOEX productive (see comment) Homsap IGHV3-11*01 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.16.38.11] CARDDSCSSGSCYEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggaggggctggagtgggtttcGatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtagtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2723 JY8QFUQ01AF9QC No results 2724 JY8QFUQ01CMAIQ unknown (see comment) Homsap IGHV2-5*03 F 114 51.04 98/192 nt 10 7 X 10.7.X [9.17.25.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2725 JY8QFUQ01B6T4I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2726 JY8QFUQ01BUZEN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame + ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacggtgtctgtgcaaatgaacagcctgagagtcgaggacacggccgtttattattgtgtgaaaaggttggagggagtggctgatgatgcttttgatatctggggcccagggacaatggtcaccgtctcttcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2727 JY8QFUQ01AE3XC productive (see comment) Homsap IGHV4-39*02 F 957 91.93 205/223 nt 91.48 204/223 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctgtctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2728 JY8QFUQ01DFO3S unknown (see comment) Homsap IGHV3-48*03 F 878 89.45 195/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactc 2729 JY8QFUQ01C2JX7 No results 2730 JY8QFUQ01B8GPR No results 2731 JY8QFUQ01BW0GE productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F (see comment) 732 81.17 181/223 nt Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 10 13 8.10.13 [1.17.38.11] CAITKIDVWGGADQW in-frame + Low V-REGION identity (81,17% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcagtttcagtggctcttctgttcactgggtccgccagacttccggaaaagggctggagtggattggccgtatcagaagtaaggcgaacgataacgcggcagtgtatcgtaagccgctgacgggcaggtttttcatctccagagatgattcacagagcacggcatatctgcaactgaacaacctgggagtcgacgacacggccacatattactgtgctatcactaaaatcgatgtttggggcggcgctgaccagtggggccaggggaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 2732 JY8QFUQ01C9KPR productive (see comment) Homsap IGHV3-30*10 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 1 8 8 16 8.8.16 [1.17.37.11] CSRGTTGTTDDSRLFQHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagcccccaaaggtcttcccgctgagccttgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2733 JY8QFUQ01DIQ0Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcagcgtctcctctgcatcccgaccagccccaaggtcttcctgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2734 JY8QFUQ01BE4D2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 822 87.38 187/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.37.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2735 JY8QFUQ01BISA3 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2736 JY8QFUQ01CWMWI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2737 JY8QFUQ01CDSVQ No results 2738 JY8QFUQ01AZ6G0 No results 2739 JY8QFUQ01DTW05 unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 862 87.84 195/222 nt 87.39 194/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [2.17.38.11] CARGGGWT#YFDSW out-of-frame - in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); gtctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacGtcgaccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattactgtgcgaggggcggtggctggacccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2740 JY8QFUQ01A4766 unknown (see comment) Homsap IGHV3-13*01 F (see comment) 356 67.44 116/172 nt 8 7 X 8.7.X [1.17.24.X] null - No rearrangement found stop codons Low V-REGION identity (67,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2741 JY8QFUQ01DGTPL No results 2742 JY8QFUQ01A5DCU unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 2743 JY8QFUQ01C3YG7 No results 2744 JY8QFUQ01BG981 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2745 JY8QFUQ01B9EKE unknown (see comment) Homsap IGHV3-7*01 F 1021 96.76 209/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagg 2746 JY8QFUQ01AN8VU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 867 87.44 195/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [1.17.38.11] CTADVPSPLAQNDFW in-frame + ctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2747 JY8QFUQ01BDIS1 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2748 JY8QFUQ01CU928 No results 2749 JY8QFUQ01A3EUV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2750 JY8QFUQ01BOI0A No results 2751 JY8QFUQ01CTN4T No results 2752 JY8QFUQ01DVYCW unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPIL** (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2753 JY8QFUQ01BKY33 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 86.51 186/215 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.16.37.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 54 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccgggaaggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagtcagtgttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2754 JY8QFUQ01C3COR productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcacgcctgcctggtccagggcttcttccccca 2755 JY8QFUQ01B035T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2756 JY8QFUQ01BT24V No results 2757 JY8QFUQ01DJJM6 productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcacctttagGtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaAagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttccttccccca 2758 JY8QFUQ01DEOHD No results 2759 JY8QFUQ01DWCV7 No results 2760 JY8QFUQ01CSAME productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + tctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2761 JY8QFUQ01COKCL No results 2762 JY8QFUQ01ALM3T unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [0.17.38.11] CAGDRGPVLGWFI*AK#YGLDVW out-of-frame + stop codons tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcggggtccggttttggggtggttcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2763 JY8QFUQ01DCCX8 unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKARIYFYGSGSYSLFDY## out-of-frame + ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggcccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2764 JY8QFUQ01A4ZWL No results 2765 JY8QFUQ01CULZK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1026 97.24 211/217 nt 96.77 210/217 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.16.38.11] CTKDKVTVGFRGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaagggctggagtgggtggcaagtatatcatatgatggaagtaataaataccatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtatctgcaaatgaacagcctgagaactgaggacacggctgtgtattattgtacgaaagacaaagtcacggtaggatttcgaggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2766 JY8QFUQ01BP9OK productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 808 86.85 185/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagttttagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2767 JY8QFUQ01CIKHF productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + cgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2768 JY8QFUQ01CIGEV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2769 JY8QFUQ01B8KNK No results 2770 JY8QFUQ01AWBZD No results 2771 JY8QFUQ01DFX3W No results 2772 JY8QFUQ01BO9X3 productive Homsap IGHV3-33*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2773 JY8QFUQ01A9HGK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2774 JY8QFUQ01C7BRV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2775 JY8QFUQ01DT5DZ No results 2776 JY8QFUQ01DP67Y productive Homsap IGHV3-11*01 F 944 93.49 201/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [0.17.38.11] CARDGDDYRSYYYGMDVW in-frame - ctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2777 JY8QFUQ01AZQUO No results 2778 JY8QFUQ01BEYVN No results 2779 JY8QFUQ01AW87R unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 342 61.75 134/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (61,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactcttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 2780 JY8QFUQ01CUCK5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 721 82.38 173/210 nt 7 8 X 7.8.X [X.17.38.X] null - No rearrangement found Low V-REGION identity (82,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2781 JY8QFUQ01CW0TP No results 2782 JY8QFUQ01BWVQL No results 2783 JY8QFUQ01DNHMW No results 2784 JY8QFUQ01CO6CM No results 2785 JY8QFUQ01B8WN1 productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatatacattgggtgcgacaggccgctggacaagggcttgagtggatgggatacatcgacccttacagaggtgacacaaggtttgcagagaaatttcagggcagggtcaccttgaccagagacacgtccatcagtacagcctacatggaaatgaccggcctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgcaccgcttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2786 JY8QFUQ01AGL4Y No results 2787 JY8QFUQ01DUXY7 productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame + ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgc 2788 JY8QFUQ01BZZIK No results 2789 JY8QFUQ01AQ4YS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2790 JY8QFUQ01DWH9C productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 2791 JY8QFUQ01AU8DV productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAKVGNLYFFEYW in-frame - tggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2792 JY8QFUQ01A25KE No results 2793 JY8QFUQ01DCE3W productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2794 JY8QFUQ01DM5DI productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F (see comment) 648 77.88 169/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-1*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRSPNHNWFDPW in-frame + Low V-REGION identity (77,88% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaaattcaataattatgcaatgcactgggtccgccagtctccaagagcggggctgcaagtgggtggcgctatatcgactgacggcaataaagaatatcatgcagactccgtgaagggccggctcaccctctccagagacaattcgaggagtacgctgtctctgcaattgcgcaacctgacagctgacgactcggctctgtattattgtgtcagatctcccaaccacaattggttcgacccctggggccagggagccctggtcactgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 2795 JY8QFUQ01BHMP6 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 2796 JY8QFUQ01CYIMP No results 2797 JY8QFUQ01AHCLK No results 2798 JY8QFUQ01BSHPP No results 2799 JY8QFUQ01BMMST unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 89 51.88 69/133 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2800 JY8QFUQ01AZRHY unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 705 91.07 153/168 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AZRHY ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 2801 JY8QFUQ01DBTL8 No results 2802 JY8QFUQ01CLWKZ unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta 2803 JY8QFUQ01B3IJX productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2804 JY8QFUQ01B6DMM No results 2805 JY8QFUQ01DQ880 No results 2806 JY8QFUQ01A9EFS unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARERGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2807 JY8QFUQ01BA7AY No results 2808 JY8QFUQ01BXHD1 No results 2809 JY8QFUQ01CH7NR productive Homsap IGHV3-72*01 F 894 89.24 199/223 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 3 8 10 10 8.10.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggactcaccttcagtgcccagtacttagactgggtccgccaggctccagggaagggactggagtgggttggccgtattagaagcaaaactaacagttacaccacagaatacgccgcgtctgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 2810 JY8QFUQ01BY2LS unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 120 54.55 72/132 nt 8 7 X 8.7.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 2811 JY8QFUQ01AJL5U productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame - tctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2812 JY8QFUQ01C1A5Y No results 2813 JY8QFUQ01CHIH6 unproductive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 418 65.74 142/216 nt 65.28 141/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.16.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,74% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaagggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2814 JY8QFUQ01CK7KN productive Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2815 JY8QFUQ01C3VSO No results 2816 JY8QFUQ01DU0CR productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 899 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtaccaagttcatgagctgggtccgccaggctccagggaaGggggctggagtgggtctcagtaatttatcctggAtggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2817 JY8QFUQ01CN93A No results 2818 JY8QFUQ01COXWN productive Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2819 JY8QFUQ01BCGF2 No results 2820 JY8QFUQ01BTB9J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccgaccgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcaccagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggcaactcag 2821 JY8QFUQ01C17IZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F (see comment) 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2822 JY8QFUQ01DGAHD productive (see comment) Homsap IGHV3-74*03 F 856 88.13 193/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); gcctctggattcacGtttccacacctcctggatgGcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2823 JY8QFUQ01BA129 No results 2824 JY8QFUQ01A5591 No results 2825 JY8QFUQ01C1UEP productive (see comment) Homsap IGHV3-9*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcagctttgatgatttgtcatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaagtattacttggaatagtggtaagattgtctatgcggactctgtgaagggccgattcaccatctccagagacaacgcccagaactccctgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2826 JY8QFUQ01BHI1R productive Homsap IGHV3-48*01 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + tctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaangtggtcgtcgcatgcctggtccagggcttcttccccca 2827 JY8QFUQ01DM8R5 unproductive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P (see comment) 357 75.38 98/130 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*02 F 2 X 5 X X.5.X [X.X.38.11] CATSPSDFDRRW#YW out-of-frame + Low V-REGION identity (75,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttagctttagaaccttttggatgagctggggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2828 JY8QFUQ01DF7UJ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 531 71.43 155/217 nt 70.97 154/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (71,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctgggttcaccttcagtgactactacatgggctGggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 2829 JY8QFUQ01CSFJ0 No results 2830 JY8QFUQ01AVSNK No results 2831 JY8QFUQ01AW6PH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2832 JY8QFUQ01DWVML unproductive Homsap IGHV3-11*01 F 819 86.64 188/217 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CADIKLGDWCFDL## out-of-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccttcagggactactatatgagttggattcgcctggcacctgggaaggggctggagtgggtttcatatattagtggtaatgtgtttaccaaacactacgcagactctgtgcagggccgattcaccatctccagggacaacgacaataagacagtctatctacagatggacaacctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccggtggcaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2833 JY8QFUQ01CDI9D No results 2834 JY8QFUQ01AZMO9 unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.16.37.11] CAGAEAGLLTY## out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgacgtactggggccctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2835 JY8QFUQ01BWD6M No results 2836 JY8QFUQ01AIAIN productive (see comment) Homsap IGHV3-7*01 F (see comment) 665 79.07 170/215 nt 78.14 168/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tgggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccgAgtggtgggtgccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgacgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2837 JY8QFUQ01B38M7 No results 2838 JY8QFUQ01BQ1XG No results 2839 JY8QFUQ01DN4L1 unknown (see comment) Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctggggccaagggtaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2840 JY8QFUQ01A7TW1 productive Homsap IGHV3-48*04 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDAGGSGWYLYYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacggcctgagagccgaggacacggctgtttattcctgtgcgagagatgcggggggcagtggctggtacctttactactttgactcctggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 2841 JY8QFUQ01CRE35 No results 2842 JY8QFUQ01DRLTE unknown (see comment) Homsap IGHV3-30*08 F 716 90.7 156/172 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found tctgcattcaacttcgatagctatactatccattgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatatgatggaggtattgaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgttgtatttac 2843 JY8QFUQ01B28TZ No results 2844 JY8QFUQ01BJPML productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 2845 JY8QFUQ01CLSSD No results 2846 JY8QFUQ01AZFFH unproductive Homsap IGHV3-48*01 F 859 88.89 192/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + tctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2847 JY8QFUQ01B3H4D No results 2848 JY8QFUQ01CYE3A productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F 142 65.38 51/78 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.26.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcacttttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2849 JY8QFUQ01C1CC3 productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtgaactcag 2850 JY8QFUQ01C2IB9 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + stop codons ctctggattcaccttcagtacatactggatgcactgggtccaccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgtaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggcgacggtgtcgtggaactcagg 2851 JY8QFUQ01DEIHL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CNLHPYGDSSDYW in-frame + ctctggactcaccttcagtcgcctctggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatagatagtgatgggaataacataatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaaaacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtaaccttcatccctacggtgactcctccgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 2852 JY8QFUQ01B1S0P unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcactttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2853 JY8QFUQ01BDCGW productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2854 JY8QFUQ01DI73D No results 2855 JY8QFUQ01BDSLH No results 2856 JY8QFUQ01BLYA9 No results 2857 JY8QFUQ01DO575 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2858 JY8QFUQ01B0VMA unknown (see comment) Homsap IGHV4-30-2*04 F, or Homsap IGHV4-34*01 F or Homsap IGHV4-34*02 F or Homsap IGHV4-34*08 F or Homsap IGHV4-34*12 F or Homsap IGHV4-34*13 F or Homsap IGHV4-38-2*01 F or Homsap IGHV4-38-2*02 F or Homsap IGHV4-39*01 F or Homsap IGHV4-39*05 F or Homsap IGHV4-59*04 F or Homsap IGHV4-59*05 F or Homsap IGHV4-59*08 F 414 91.0 91/100 nt X X X X.X.X [X.X.33.X] null + No rearrangement found stop codons tctatggagtcgagtcaccatatgagtagacacctccaagaaccagttctccctgaaggtgagctctgtgatcgccgcagacacggctgtgtattactgtgcgagacgtaagggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 2859 JY8QFUQ01DIDLY No results 2860 JY8QFUQ01AGHR6 No results 2861 JY8QFUQ01B3QIS No results 2862 JY8QFUQ01BBO0P No results 2863 JY8QFUQ01CHNGE No results 2864 JY8QFUQ01AXQ8Q No results 2865 JY8QFUQ01BFQXZ No results 2866 JY8QFUQ01DS8C4 unproductive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-7*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREGGITGTTG#NWFDPW out-of-frame - ctctggattcacctttagtaactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaatcaagatggacgtgagaaatactttgtggactctgtgaagggccgattcatcatctcccgagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggctgtgtattactgtgcgagagagggcggtataactggaactacagggggaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2867 JY8QFUQ01A5YKU No results 2868 JY8QFUQ01BL86G productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 7 8 12 7.8.12 [0.17.38.11] CARGPVSGWYGDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tggatacatcttcaaaactactatatattctgggtgcgacgggcccctggacaagggcttgagtggatgggttgggtcaaccctaacagtggtgccacacactatgcaccgaaatatcagggccgggtcaccatgaccagggacacgtcattcgccacagcctacatggatttgagcatgttgacatctgacgacacggccatgtattactgtgcgagaggccctgtcagtggttggtatggtgacttctggggccagggaaccctagtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2869 JY8QFUQ01B0XNO productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 867 89.72 192/214 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + atatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcctctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2870 JY8QFUQ01C6TP1 No results 2871 JY8QFUQ01AZ8FQ productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggGcagttatatcatatgatggaaaaaagtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2872 JY8QFUQ01B8ECU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ctctggactcagtttcactaacgcctggatgagctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttct 2873 JY8QFUQ01AEE1L No results 2874 JY8QFUQ01C4IDC No results 2875 JY8QFUQ01AYEER productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.37.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgagggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2876 JY8QFUQ01CTAVK unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 95 82.14 23/28 nt 7 X X 7.X.X [2.X.X.X] null + No rearrangement found tctccgggggacagtgtctctagcaaca 2877 JY8QFUQ01AYTFX No results 2878 JY8QFUQ01BJDN7 productive Homsap IGHV1-24*01 F 956 94.81 201/212 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 7 8 7 7.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaacctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2879 JY8QFUQ01AOOZC No results 2880 JY8QFUQ01BQN6H No results 2881 JY8QFUQ01C9EJA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 270 68.25 86/126 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found Low V-REGION identity (68,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 2882 JY8QFUQ01AS3R6 No results 2883 JY8QFUQ01CE8RM No results 2884 JY8QFUQ01CT2ZA productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2885 JY8QFUQ01A0ZPP No results 2886 JY8QFUQ01CIO2I unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 493 92.92 105/113 nt 92.04 104/113 nt 8 8 X 8.8.X [1.16.4.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagac 2887 JY8QFUQ01BXRY4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2888 JY8QFUQ01BZZMG No results 2889 JY8QFUQ01DE40U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'AG' (2 nucleotides at position 38 to 39 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcgctatagcatgaactAGggtgccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2890 JY8QFUQ01DAKI0 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 559 78.57 143/182 nt 8 8 X 8.8.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtggaactcag 2891 JY8QFUQ01DMMHT No results 2892 JY8QFUQ01CAJ88 No results 2893 JY8QFUQ01DCYGN productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2894 JY8QFUQ01ADWC9 No results 2895 JY8QFUQ01DV6H5 productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 83 to 88 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacgGggcccctggacAaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2896 JY8QFUQ01DPNFS unknown (see comment) Homsap IGHV3-7*01 F 953 93.95 202/215 nt 93.02 200/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctggagtgggtggccaacataaagGcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 2897 JY8QFUQ01A7VUV productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaatcacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2898 JY8QFUQ01DXIXR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 154 89.47 34/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcaccttcagtcagtactggatgtactggg 2899 JY8QFUQ01AEOM7 No results 2900 JY8QFUQ01CEVZB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 971 94.88 204/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDTLEVVSNMDDAFDL## out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaattacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2901 JY8QFUQ01COTVM No results 2902 JY8QFUQ01CV25T productive Homsap IGHV3-48*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 2903 JY8QFUQ01C113P No results 2904 JY8QFUQ01CUZAY No results 2905 JY8QFUQ01CRNOZ unknown (see comment) Homsap IGHV3-74*03 F, or Homsap IGHV3-NL1*01 F 124 55.74 68/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 2906 JY8QFUQ01C7IZ8 No results 2907 JY8QFUQ01COZH8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAREGGRGSSSEDYFDYW in-frame + ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagagggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2908 JY8QFUQ01A186V No results 2909 JY8QFUQ01C9067 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 83 51.54 67/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2910 JY8QFUQ01C4OEJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2911 JY8QFUQ01A9CVU No results 2912 JY8QFUQ01BSB46 No results 2913 JY8QFUQ01ASL2A No results 2914 JY8QFUQ01CF7TY productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggattcacCctttggttattatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2915 JY8QFUQ01CTQQY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CARALIVVAGAPVYW# out-of-frame + ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcgccatctcaagagacaacgacaagaactcactgtatctgcaaatgaccagcctgagagccgaggacacggctgtctactactgtgcgagagccctaatagtagtggctggtgcccctgtctattgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2916 JY8QFUQ01DEGFN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2917 JY8QFUQ01DOW2F unproductive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDGGSSGWFGRC#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggcagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2918 JY8QFUQ01AFH3O No results 2919 JY8QFUQ01ATHAC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2920 JY8QFUQ01AKNG3 No results 2921 JY8QFUQ01BAEXS No results 2922 JY8QFUQ01DXCKR No results 2923 JY8QFUQ01AWHNG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [2.17.38.11] CANELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); agcctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2924 JY8QFUQ01A073Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKSVSSGWPIDEIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggcgtgggagtgggtctcagccattagtggcagtggtagtcggacatattacgcagactccgtgaagggccggttcaccatctccagagacaagtccaagaaaacgttgtatctacaaatgaacagcctgagagccgaggacacggccactttctattgtgcgaagagtgtgagtagtggctggccgatcgacgaaattgactactggggccaggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2925 JY8QFUQ01A54Y4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2926 JY8QFUQ01C21UC No results 2927 JY8QFUQ01B32AH No results 2928 JY8QFUQ01DFRMM productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 9 9 14 9.9.14 [X.17.38.11] CARGGDYYDSGGLDYW in-frame + ggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2929 JY8QFUQ01C2MXI No results 2930 JY8QFUQ01BCJET productive (see comment) Homsap IGHV3-11*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2931 JY8QFUQ01CHVRC No results 2932 JY8QFUQ01C6A6Y unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 890 97.33 182/187 nt 8 8 X 8.8.X [2.17.27.X] null - No rearrangement found gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcc 2933 JY8QFUQ01AVPQN unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 705 91.07 153/168 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AVPQN ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 2934 JY8QFUQ01BHHKX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2935 JY8QFUQ01BHJF4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.16.38.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccgggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2936 JY8QFUQ01AMZZA productive (see comment) Homsap IGHV4-61*02 F 890 90.7 195/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [2.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGTTA' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctccggtggctccatcagtacTGGTTAttactactgGgagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaAacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2937 JY8QFUQ01B8EPZ No results 2938 JY8QFUQ01DH1RB No results 2939 JY8QFUQ01DAIQP No results 2940 JY8QFUQ01DDO4S No results 2941 JY8QFUQ01DTUTS No results 2942 JY8QFUQ01DS5IV No results 2943 JY8QFUQ01BJXDC unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 235 60.37 99/164 nt 7 8 X 7.8.X [X.17.22.X] null - No rearrangement found Low V-REGION identity (60,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 2944 JY8QFUQ01C1TQQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 169 58.78 77/131 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found tctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2945 JY8QFUQ01ALRLE unproductive Homsap IGHV1-3*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [1.17.38.11] CARDGYLPGNGAD#W out-of-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtcttaataactactggatgacctgggtccgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgactttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 2946 JY8QFUQ01C7XPE No results 2947 JY8QFUQ01CNQRD No results 2948 JY8QFUQ01C2CGB No results 2949 JY8QFUQ01AB3LB unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CAKDLVVTSIGPQGIHGH## out-of-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 2950 JY8QFUQ01DIUF8 productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame + ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2951 JY8QFUQ01CLVLV No results 2952 JY8QFUQ01A6B5R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [2.17.38.11] CTKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtacgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2953 JY8QFUQ01DO9XE No results 2954 JY8QFUQ01AF5OM No results 2955 JY8QFUQ01DLOAU unknown (see comment) Homsap IGHV3-11*01 F 954 93.55 203/217 nt 93.09 202/217 nt 8 7 X 8.7.X [2.17.38.X] null - No rearrangement found in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) agcctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2956 JY8QFUQ01CCZ4E unproductive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 1 10 7 X 10.7.X [1.17.38.11] CARCPNYNIGTR#FDYW out-of-frame - tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 2957 JY8QFUQ01A22P2 No results 2958 JY8QFUQ01BA422 productive (see comment) Homsap IGHV3-7*01 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 7 8 10 7.8.10 [1.17.38.11] CIMDLVGRADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) cctctggattcaccttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2959 JY8QFUQ01AVP09 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 335 88.37 76/86 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame - tcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2960 JY8QFUQ01AG0D6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2961 JY8QFUQ01DROJA No results 2962 JY8QFUQ01B4VR2 unproductive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.37.11] CARDLEVPTI*W#YW out-of-frame - stop codons in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2963 JY8QFUQ01DU9R7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcgatagttactacCtggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 2964 JY8QFUQ01CW9IN unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 770 83.49 182/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatggaatgcgtggtcgtcgcatgcctggtccagggcttcttccccca 2965 JY8QFUQ01C9BGT No results 2966 JY8QFUQ01AG377 unproductive Homsap IGHV3-7*01 F 938 92.99 199/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [0.17.38.11] CVRDRFMIVVVMSLGNWG#YSDHW out-of-frame - tggattcacatttagtaactactggatgagctgggtccgccaggntccagggaaggggctggagtgggtggccaacntaaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgatttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2967 JY8QFUQ01CA2V4 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 2968 JY8QFUQ01AAUM2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2969 JY8QFUQ01BODE6 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 2 8 8 8 8.8.8 [1.17.38.11] CARGRPQPHW in-frame + ctctggattcacctttagtacctattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataacgccagatggaagtgacagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgctaagagttcactgtttctccaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggacggccccaaccccactggggccggggaaccctggtcatcgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 2970 JY8QFUQ01CU3QA No results 2971 JY8QFUQ01BH32Y No results 2972 JY8QFUQ01DVZ77 No results 2973 JY8QFUQ01DALUO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctacattcgGcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattaatgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2974 JY8QFUQ01DV5EE No results 2975 JY8QFUQ01AERR3 No results 2976 JY8QFUQ01B35KF No results 2977 JY8QFUQ01AHF1U No results 2978 JY8QFUQ01BPQ6O productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2979 JY8QFUQ01AY2PJ unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2980 JY8QFUQ01DVBKX unknown (see comment) Homsap IGHV3-48*02 F 949 93.06 201/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcagcttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccataaactatgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 2981 JY8QFUQ01CTJRF unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 157 57.46 77/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 2982 JY8QFUQ01AM3C3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2983 JY8QFUQ01DU3W2 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt 90.62 203/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatTgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2984 JY8QFUQ01A0AUL unknown (see comment) Homsap IGHV3-66*02 F (see comment) 649 82.2 157/191 nt 81.68 156/191 nt 7 7 X 7.7.X [1.17.31.X] null + No rearrangement found stop codons Low V-REGION identity (82,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcaccgtcaatagaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaaggactacttcccgaaccggtgacggtgtcgtggaactcag 2985 JY8QFUQ01C4BFT No results 2986 JY8QFUQ01BHV1C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacaGccctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2987 JY8QFUQ01AB23J unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 471 71.28 139/195 nt 70.77 138/195 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AB23J ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgagggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2988 JY8QFUQ01DQCQO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 2989 JY8QFUQ01BHPGU No results 2990 JY8QFUQ01BLE2H No results 2991 JY8QFUQ01DEYF4 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 811 85.84 188/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2992 JY8QFUQ01A0J40 unknown (see comment) Homsap IGHV3-48*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcaaaaagtatggcatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 2993 JY8QFUQ01BCT87 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 611 75.81 163/215 nt 75.35 162/215 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2994 JY8QFUQ01DSKER unknown (see comment) Homsap IGHV3-13*05 F 98 50.27 94/187 nt 8 6 X 8.6.X [1.17.30.X] null - No rearrangement found tctggactcaccttcagtagcttcgacatgcactgggtccgcaaacctacacgaaaagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 2995 JY8QFUQ01C2Q5E No results 2996 JY8QFUQ01C602K No results 2997 JY8QFUQ01AWD51 No results 2998 JY8QFUQ01AOWN0 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 259 72.12 75/104 nt 8 7 X 8.7.X [1.17.1.X] null + No rearrangement found Low V-REGION identity (72,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttcccca 2999 JY8QFUQ01CUPL9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CSNGYGDFPRR## out-of-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3000 JY8QFUQ01DN0GK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggagggAccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3001 JY8QFUQ01AH6J6 unproductive (see comment) Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3002 JY8QFUQ01ASCI5 No results 3003 JY8QFUQ01CJAMU No results 3004 JY8QFUQ01AU72L No results 3005 JY8QFUQ01BFHSP productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctgggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3006 JY8QFUQ01AXUG2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3007 JY8QFUQ01DP8EA productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3008 JY8QFUQ01BYFM4 productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3009 JY8QFUQ01B7IXH No results 3010 JY8QFUQ01AV68T productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3011 JY8QFUQ01DIUW1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) agcctccgaattcatccttgacagttatgccatgagttgggtccgcaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3012 JY8QFUQ01AILJF No results 3013 JY8QFUQ01A018V productive Homsap IGHV4-61*02 F 811 85.84 188/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3014 JY8QFUQ01C7SVR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.16.38.11] CARDPYNGGGYSAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatagtgcttttgatatctggggccaaggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3015 JY8QFUQ01CQ4I9 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3016 JY8QFUQ01DC1W2 No results 3017 JY8QFUQ01DSY6A productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggccaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacgtgtcgtggaactca 3018 JY8QFUQ01AUI27 No results 3019 JY8QFUQ01ASKXZ productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaaaaaaagtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3020 JY8QFUQ01BE8R5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3021 JY8QFUQ01C7K91 No results 3022 JY8QFUQ01CEWEC No results 3023 JY8QFUQ01C6CVD No results 3024 JY8QFUQ01DAS90 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 504 92.31 108/117 nt 91.45 107/117 nt 8 8 X 8.8.X [1.16.5.X] null + No rearrangement found in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca 3025 JY8QFUQ01DA6DQ No results 3026 JY8QFUQ01CB5ZL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 3027 JY8QFUQ01BSEF6 No results 3028 JY8QFUQ01BLIG3 No results 3029 JY8QFUQ01AO498 No results 3030 JY8QFUQ01A7MWW productive Homsap IGHV3-9*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 3031 JY8QFUQ01AAQ5Z productive Homsap IGHV4-61*02 F 821 85.52 189/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.38.11] CARENYYGSGSYGRAWFDYW in-frame + tctctggaggctccatcagcagtggaagctacttctggacctggatccggcagcccgccgggaaggatctggagtggattgggcgcttctacagtagtgacagtgtcgactacaacccctccctcaggggtcgagccaccatttcagcggacacgtccaagagccagttctcccttaatctgaagtctgcgaccgccgcagacacggccgtttattactgcgcgagagagaattactacggttcggggagttatgggcgggcctggtttgactactggggcccgggaatccaggtcaccgtctctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3032 JY8QFUQ01CJCMS productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 7 7 13 7.7.13 [1.17.38.11] CARPHHNSGYSFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gtctgatttcaacgtcggtgacttgacatgcactgggtccgccagactccagacaaggggctggagtgggtggcactttttggtatgacggaaagaggaaatattatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatggacagcctgagagccgacgacacggctacctacttttgtgcgaggcctcatcataatagtggttattcctttgaccactggggccagggaacccaggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 3033 JY8QFUQ01AEVED unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 130 55.22 74/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3034 JY8QFUQ01A1HD7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtaactacCtggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3035 JY8QFUQ01DLCBP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3036 JY8QFUQ01BOBM0 No results 3037 JY8QFUQ01DIODI productive (see comment) Homsap IGHV1-18*01 F 845 88.37 190/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'GCC' (3 nucleotides at position 8 to 10 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'AGG' (3 nucleotides at position 47 to 49 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ctggttaGCCccctttaaatacctatggtatcacctgggtgcgacaAGGgccccctgaacacggccttgagtggatAggggtggatcagcgttcacgatggcaacacaaactatgcacagaatctccagggcagagtcaccctgaccacagacacatctacgagcacagcctacatggaactgaggggtctcagatctgacgacacggccgtttattattgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3038 JY8QFUQ01CY80E No results 3039 JY8QFUQ01CY9YF No results 3040 JY8QFUQ01AJ3WA productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + tctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3041 JY8QFUQ01CQ4SH No results 3042 JY8QFUQ01C4GKI No results 3043 JY8QFUQ01DE5HN productive (see comment) Homsap IGHV3-48*01 F 1016 97.21 209/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 7 10 8.7.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtggtatatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3044 JY8QFUQ01CWVA7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3045 JY8QFUQ01DIGYO No results 3046 JY8QFUQ01DMW4C No results 3047 JY8QFUQ01CRVX3 unknown (see comment) Homsap IGHV3-38*01 ORF, or Homsap IGHV3-38*02 ORF or Homsap IGHV3-38*03 ORF or Homsap IGHV3-38-3*01 ORF or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 100 100.0 20/20 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found tctggattcaccgtcagtag 3048 JY8QFUQ01A8WP7 No results 3049 JY8QFUQ01DKRMQ unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 198 57.31 98/171 nt 8 8 X 8.8.X [1.17.23.X] null - No rearrangement found tctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatacattagtagcaatggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3050 JY8QFUQ01BDI9Q No results 3051 JY8QFUQ01C39OT productive (see comment) Homsap IGHV4-4*07 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [2.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'T' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); gtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagCcccccactacaacccctTccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccacttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3052 JY8QFUQ01DOM0M No results 3053 JY8QFUQ01BM6Z0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - tctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3054 JY8QFUQ01CCPRB unproductive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 805 86.11 186/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtggcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3055 JY8QFUQ01CKINT No results 3056 JY8QFUQ01BME7S No results 3057 JY8QFUQ01AU45S unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac 3058 JY8QFUQ01B7PED No results 3059 JY8QFUQ01BGLLH productive Homsap IGHV3-9*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKVGSQWELLRPIDYW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagtggggtcccagtgggagctactaaggcccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccc 3060 JY8QFUQ01DCQBH No results 3061 JY8QFUQ01BX1V4 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-21*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSVGRYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); cctcggggttcagcgtcaataataacttcatgacttggttccgccaggttccagggaaggggctggagtgggtctcagttatctataCaaaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccgagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtactactgtgcgagagaatttcgggcgccttctgtgggcagatatggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3062 JY8QFUQ01CKNLX No results 3063 JY8QFUQ01BRVNO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CAKKSDINNIGWHGLFDYW in-frame - ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggagggggctggagtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcgaaaaaatcggatataaataacattggctggcacggcctatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3064 JY8QFUQ01AS24X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3065 JY8QFUQ01CUTTF No results 3066 JY8QFUQ01CXBZV No results 3067 JY8QFUQ01DJTMW No results 3068 JY8QFUQ01C16HI No results 3069 JY8QFUQ01DG5DA No results 3070 JY8QFUQ01BARXE unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 146 53.26 98/184 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found tctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 3071 JY8QFUQ01AV09F productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3072 JY8QFUQ01AHMII No results 3073 JY8QFUQ01AF6XR No results 3074 JY8QFUQ01BLD2R No results 3075 JY8QFUQ01CU4F2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGAAV#FNSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttaacagccatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtgcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 3076 JY8QFUQ01DHXZ0 No results 3077 JY8QFUQ01AUXE0 No results 3078 JY8QFUQ01AX27R No results 3079 JY8QFUQ01B70HN No results 3080 JY8QFUQ01CVUKJ No results 3081 JY8QFUQ01B127A unknown (see comment) Homsap IGHV3-23*05 F 100 55.45 56/101 nt 54.46 55/101 nt 7 8 X 7.8.X [1.17.X.X] null + No rearrangement found stop codons in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctggattcgtcttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 3082 JY8QFUQ01BW6UO No results 3083 JY8QFUQ01A24XX No results 3084 JY8QFUQ01BK2W2 No results 3085 JY8QFUQ01AXQ6G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3086 JY8QFUQ01AY7GI productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 3087 JY8QFUQ01BS0WR No results 3088 JY8QFUQ01B1DTR No results 3089 JY8QFUQ01AMDJ3 No results 3090 JY8QFUQ01DWKAP unproductive Homsap IGHV3-74*03 F (see comment) 842 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] XVLEIQTVAPRTSP#W out-of-frame - Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcactttccacacctcctGggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattatttngtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 3091 JY8QFUQ01BSH4W No results 3092 JY8QFUQ01DKKW7 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3093 JY8QFUQ01DOWWF No results 3094 JY8QFUQ01BVC70 No results 3095 JY8QFUQ01CHHAT No results 3096 JY8QFUQ01BAK7Q No results 3097 JY8QFUQ01B0F0I No results 3098 JY8QFUQ01COB21 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3099 JY8QFUQ01DE3I7 productive Homsap IGHV4-61*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERSISIGGAREFDSW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcactggtggccccatgggcagtagtttatacttctggaattgggtccgacagcccgccgggaagagactggagtggatcggacgtgtttatgatgatgggagtacccgctacaatccctccctcaggggtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaggttgagttttgtgaccgccgcagacacggcccgttattactgtgcgagagaacggagtatttcgattggcggagcgagagaatttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3100 JY8QFUQ01DAOHD unknown (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctcttccaccaagggcccatccgtcttccccctggcgccctgctccaggcagcacctccgagagcacagccgcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3101 JY8QFUQ01DG09I No results 3102 JY8QFUQ01B4ZK0 No results 3103 JY8QFUQ01AR168 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 8 7 12 8.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcaataattacttctggacctggatccgccagTcccccagggaaggggccggagtggattggggaaatcaatcatagtggtagcaccaactacaatccgtccctcaagagtcgagtcaccatctcaatagacacgtccaagatccagttctccctgcagctgagctctgtgaccgccgcggacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3104 JY8QFUQ01CGD2D productive Homsap IGHV1-58*02 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame - tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3105 JY8QFUQ01BJIX5 unproductive Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag 3106 JY8QFUQ01DV19Z unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga 3107 JY8QFUQ01DI014 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 3108 JY8QFUQ01DOBZY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3109 JY8QFUQ01BQ9WT No results 3110 JY8QFUQ01AZQ2B productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3111 JY8QFUQ01CF936 unproductive Homsap IGHV3-7*01 F 975 95.33 204/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.37.11] CAKGVVTA#LDYW out-of-frame + in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaatttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 3112 JY8QFUQ01CGZG3 No results 3113 JY8QFUQ01AICJL No results 3114 JY8QFUQ01B3B91 No results 3115 JY8QFUQ01ACBJX unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 263 72.82 75/103 nt 71.84 74/103 nt 8 7 X 8.7.X [1.16.1.X] null + No rearrangement found Low V-REGION identity (72,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) tctggcttcaccgtcaataacaactacatggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttcctcca 3116 JY8QFUQ01AWJ7L No results 3117 JY8QFUQ01BWBZA No results 3118 JY8QFUQ01DGGFP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctagattcaccttcagtagctataatatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 3119 JY8QFUQ01AQQ9J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3120 JY8QFUQ01BJLT6 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 737 82.79 178/215 nt 82.33 177/215 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.37.11] CARIWDSWSGAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgagggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagagcttcttccccca 3121 JY8QFUQ01DNCVB No results 3122 JY8QFUQ01BX1Y8 No results 3123 JY8QFUQ01DFBZM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtaCtaaaaagctacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 3124 JY8QFUQ01B0LE9 No results 3125 JY8QFUQ01COKDY No results 3126 JY8QFUQ01CAZ5U No results 3127 JY8QFUQ01A8OUJ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3128 JY8QFUQ01DDPR3 productive (see comment) Homsap IGHV3-9*01 F 986 94.95 207/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKSGTYSSSSGHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcaactttaataaGttatgccatgcactggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3129 JY8QFUQ01B6NV3 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRLNGDYTFGA#FDLW out-of-frame + stop codons Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaacggtgactacacattcggcgcattttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 3130 JY8QFUQ01AVE52 No results 3131 JY8QFUQ01CG3T2 unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F (see comment) 246 84.06 58/69 nt 8 X X 8.X.X [0.14.X.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttcttccccc 3132 JY8QFUQ01CTRTT No results 3133 JY8QFUQ01A66X0 No results 3134 JY8QFUQ01AQ3MO No results 3135 JY8QFUQ01B7SCL No results 3136 JY8QFUQ01BLUZD unproductive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARVIPGRGK##AFDVW out-of-frame + stop codons ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggcaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 3137 JY8QFUQ01AU8LW No results 3138 JY8QFUQ01CP1IY No results 3139 JY8QFUQ01B80QR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 619 93.62 132/141 nt 92.2 130/141 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 X 7.1.X [1.X.37.11] CVMRFGWSERF#W out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01B80QR ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttatgcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3140 JY8QFUQ01C7HP4 No results 3141 JY8QFUQ01ADZ41 No results 3142 JY8QFUQ01BAYGY No results 3143 JY8QFUQ01AYQGT productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3144 JY8QFUQ01CNYI4 No results 3145 JY8QFUQ01BXVRF No results 3146 JY8QFUQ01CRHFL No results 3147 JY8QFUQ01AH5QJ productive Homsap IGHV3-64*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVTCGDYSYEYW in-frame - ctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3148 JY8QFUQ01BLQS0 No results 3149 JY8QFUQ01A7LAD No results 3150 JY8QFUQ01ALUCO unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 853 89.2 190/213 nt Homsap IGHJ3*02 F (see comment) 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CARPTYSSGRD#AFDTW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggactgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3151 JY8QFUQ01AO1ZP No results 3152 JY8QFUQ01DLDAU No results 3153 JY8QFUQ01DKHL3 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 999 93.81 212/226 nt 92.92 210/226 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 10 9 19 10.9.19 [1.16.38.11] CARASRRDRQSDRNYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) cctccggggacagtgtctctagcaacagtgccacAttggaactggatcaggcagtccccaacggaggccttgagtggctgggaaggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtcagtctgatcggaactactatgagctggacttctggggccagggaatcttggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3154 JY8QFUQ01AP4EW No results 3155 JY8QFUQ01DBAHL No results 3156 JY8QFUQ01C4HCZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt 87.16 190/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) agcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3157 JY8QFUQ01BPIK6 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3158 JY8QFUQ01AISKV No results 3159 JY8QFUQ01BASM2 unknown (see comment) Homsap IGHV3-23*05 F 97 54.81 57/104 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3160 JY8QFUQ01CMQFU No results 3161 JY8QFUQ01BWGBV No results 3162 JY8QFUQ01B2BAU No results 3163 JY8QFUQ01DGYOV No results 3164 JY8QFUQ01A0QXW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt 99.53 213/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3165 JY8QFUQ01AX2ZP No results 3166 JY8QFUQ01DS6X3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 977 94.5 206/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARGVGQQLPPLDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'CC' (2 nucleotides at position 27 to 28 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ctgtctctCgctgcctccatcaatagCCtttttactggagctggatccggcagcccccagggaagggactggagtggattggatatatctaCtgatagtgggagcaccaactacaAacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3167 JY8QFUQ01CEPQD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccaggaagctttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3168 JY8QFUQ01BXDO8 No results 3169 JY8QFUQ01C04M5 No results 3170 JY8QFUQ01BQRTA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 498 83.69 118/141 nt 8 8 X 8.8.X [2.17.12.X] null - No rearrangement found Low V-REGION identity (83,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca 3171 JY8QFUQ01DMVX2 productive (see comment) Homsap IGHV3-7*01 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.16.38.11] CARDPYNGGGYGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3172 JY8QFUQ01CAM4X No results 3173 JY8QFUQ01DO7TR unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 3174 JY8QFUQ01CF2XO unproductive (see comment) Homsap IGHV4-4*07 F 854 88.84 191/215 nt 87.91 189/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaatggcatttaCctggagttggattcgacaatccgccggaaagggactggagtggattgggcgcatccataccagtgggagcaccaactacaaccCcctccctcaaaagtcgagtcaccatgtcgatagacacgtccaagaaccagttctccctaaggttgacctctgtgaccgccgcggacacggccatttattactgtgcaaaagacatacaggatgaggataattactgggggccagggagcccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3175 JY8QFUQ01B6D3V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag 3176 JY8QFUQ01DHZV7 unproductive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGFTV#HFDSW out-of-frame - tggatacaccttcagcgactactacatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggctgaaccctaataatggtgacacagcttatggccagagctttcagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggctttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3177 JY8QFUQ01BKMU4 No results 3178 JY8QFUQ01C1OCG No results 3179 JY8QFUQ01AXBZZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3180 JY8QFUQ01DU14G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame + gtctggattcacgtttagaaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3181 JY8QFUQ01B2IY1 unproductive Homsap IGHV4-4*07 F (see comment) 1016 97.21 209/215 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [1.17.38.11] CARDFSNRGWYFDL# out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01B2IY1 ; 8 AA in Homsap_IGHV4-4*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctctggtgactccatttccagtactagttattactggggctgggtccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctgggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3182 JY8QFUQ01BM5OL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 766 87.06 175/201 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 4 8 14 4.8.14 [X.17.38.11] CAKEEGATGVYYVDHW in-frame - accacctccgccatggcctgggtccgccaggttccagggaaggagctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3183 JY8QFUQ01BQWVC unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 694 81.43 171/210 nt 8 7 X 8.7.X [X.17.38.X] null + No rearrangement found Low V-REGION identity (81,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 3184 JY8QFUQ01DJP57 No results 3185 JY8QFUQ01DLJ14 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 7 8 8 7.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift) gcctctggggttcgccgtcagtagcaagtcatgagttgggtccgccaggctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3186 JY8QFUQ01C6DJA unproductive (see comment) Homsap IGHV3-7*01 F (see comment) 414 65.44 142/217 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.17.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,44% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaagcgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3187 JY8QFUQ01CHUV9 productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3188 JY8QFUQ01BVKTT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 428 77.24 112/145 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found Low V-REGION identity (77,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttcccc 3189 JY8QFUQ01BGC9V No results 3190 JY8QFUQ01COBGR unproductive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGGSSGWFGRCGRL# out-of-frame + gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggcagcagtggctggtttggacgttgtggacgtctggggccaagggtaccacggtcaccgtcgcctcagcctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3191 JY8QFUQ01DTF77 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 92.13 199/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + tctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 3192 JY8QFUQ01CYJU0 No results 3193 JY8QFUQ01AP21C productive (see comment) Homsap IGHV1-18*01 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 104 of V-REGION: 'T' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); tggttacccctttaatacctatggtatcacctgggtgcgacaggCcccctggacacggccttgagtggatggggtggatcagcgttcacgatggcaacacaaactatgcacagaatctccagggcagagtcaccctgaccacagacacatctacgagcacagcctacatggaactgaggggtctcagatctgacgacacggccgtttattatTtgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3194 JY8QFUQ01AAP53 No results 3195 JY8QFUQ01BAO9A productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 7 18 8.7.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3196 JY8QFUQ01B4NFZ unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPIL** (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3197 JY8QFUQ01A2KWU unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 567 73.27 159/217 nt Homsap IGHJ2*01 F 31 64.71 11/17 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.5] PV## out-of-frame + Low V-REGION identity (73,27% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3198 JY8QFUQ01BCEXD No results 3199 JY8QFUQ01CYZLO No results 3200 JY8QFUQ01DV3LY productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARVDFYGSSKYKGFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gtctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3201 JY8QFUQ01CJWCW No results 3202 JY8QFUQ01B9JK5 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3203 JY8QFUQ01BJSP8 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 676 80.38 168/209 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found Low V-REGION identity (80,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagcacgaccataggctacgcagactctgtgaggggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggatagcctgcctggtccagggcttcttcccca 3204 JY8QFUQ01DSDCP unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-3*02 F 2 8 8 X 8.8.X [1.17.38.11] CATYGRFSFSPLDY## out-of-frame - gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactgggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3205 JY8QFUQ01B2EAY No results 3206 JY8QFUQ01BQM0J No results 3207 JY8QFUQ01CD3DH productive (see comment) Homsap IGHV3-7*03 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctagattcacctttaatggttaCtgggatgagttgggtccgccaggctccaggaaAaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3208 JY8QFUQ01BGNVA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.37.11] CAKERDNNVLPVDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgagggccggttcaccgtctccagagacaatttcaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 3209 JY8QFUQ01BCL4D No results 3210 JY8QFUQ01BT6IL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 99.54 216/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt 8 8 16 8.8.16 [1.17.38.11] CAYGGMTRWLAHQFDYWG (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgcgcatatgggggcatgacgcggtggctggctcaccagtttgactactggggcccaggggaacccctggtcaccgtctcctcagggagtgcatccgcccccaaccctt 3211 JY8QFUQ01CE5ND productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF (see comment) 887 91.87 192/209 nt 90.43 189/209 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [0.15.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CE5ND ; 8 AA in Homsap_IGHV3-20*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 4 nucleotides (from position 74 in the user submitted sequence), (cause frameshift) ctggattcacctttggttattatggcatgagctgggtccgccaagctccagggagggcgtggagtggtctctgtatatcggatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3212 JY8QFUQ01DAOOD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3213 JY8QFUQ01CGF4V productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3214 JY8QFUQ01CNJJ3 productive Homsap IGHV4-59*08 F 1061 99.53 214/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARGYCSNAVCYQIMNW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggcctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 3215 JY8QFUQ01AQVWM No results 3216 JY8QFUQ01DJRT2 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 3217 JY8QFUQ01BOVP9 No results 3218 JY8QFUQ01BXC3X unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 193 93.18 41/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagcaagtatgccatgagctgggtccgcca 3219 JY8QFUQ01BJMU2 No results 3220 JY8QFUQ01BJQK4 No results 3221 JY8QFUQ01BE7WZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + tctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3222 JY8QFUQ01B4PWC productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3223 JY8QFUQ01AZ8A1 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 731 81.45 180/221 nt Homsap IGHJ4*02 F (see comment) 114 70.83 34/48 nt Homsap IGHD3-16*02 F 2 10 7 X 10.7.X [1.17.38.11] CARERAASSH*RVRELDF## out-of-frame + stop codons Low V-REGION identity (81,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctctggtgactccattaccagtggtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagcgggctgccagttcgcattgacgagtgagagaacttgacttctggggccagggggaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3224 JY8QFUQ01C02Y6 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3225 JY8QFUQ01DEMQ9 unproductive (see comment) Homsap IGHV3-30*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKN*PVLGHNRALP*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaattgacctgtcttggggcacaatagagcactaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtagtcatcgcctgcctggtccagggcttcttcccccag 3226 JY8QFUQ01DS8S2 productive Homsap IGHV3-48*03 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3227 JY8QFUQ01A58CS productive Homsap IGHV3-7*03 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3228 JY8QFUQ01DNNPU unproductive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F (see comment) 387 64.52 140/217 nt 63.59 138/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [2.17.38.11] CTRELRVAAARDGVDIW in-frame - stop codons Low V-REGION identity (64,52% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'ATG' (3 nucleotides at position 61 to 63 in the user submitted sequence), (do not cause frameshift); gcctctggattcaccgtcagtaccaaggtTcatgagctgggtccgccaggctccagggcaATGggggctggagtgggtctcagtaactttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3229 JY8QFUQ01DINN6 No results 3230 JY8QFUQ01CO8CX No results 3231 JY8QFUQ01AOHOF productive Homsap IGHV4-59*03 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatccggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3232 JY8QFUQ01AH1TD No results 3233 JY8QFUQ01ASY07 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD4-11*01 ORF 2 8 8 11 8.8.11 [2.16.37.11] CVKAGDISWYDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 209 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagcagctacaccatgggctgggtccgccaggctccagggaagggctggagtgggtctcagatatcaataggagcggtggtacgacatactacgtagactccgtgaggggccggttcaccatttccngagacaactccaaaaacacgctgtatctgcagatggacagcctgagagtcgaggacacggccatttttactgtgtgaaagccggcgacatcagttggtacgactactggggccagggagccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3234 JY8QFUQ01B02NC No results 3235 JY8QFUQ01DI29B No results 3236 JY8QFUQ01DFAXC productive (see comment) Homsap IGHV3-9*02 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ2*01 F (see comment) 157 77.36 41/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [2.16.38.11] CARAPSVTFSGQGHYYDLW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) aggcactggattcagctctgagaattatgccatgcactgggtccggcagcctccaggaagggcctagagtgggtctcacacatcagttggaatggcgaaggcatcgactacgcggactcagtgaagggccgattcaccgtctccagagacaacggcaagaattccctgtatttgcaaatgaacagtctgacaactgacgacacggccttgtattactgtgcaagagccccttcagtcacattcagcgggcaggggcactactatgatctctggggccgtggcaccctggtcgtggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3237 JY8QFUQ01A6G0B unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 302 96.88 62/64 nt 8 X X 8.X.X [1.12.X.X] null - No rearrangement found tctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaaggggctgg 3238 JY8QFUQ01BOYGD No results 3239 JY8QFUQ01C2U0I No results 3240 JY8QFUQ01BF4BW No results 3241 JY8QFUQ01DN8Y7 unproductive Homsap IGHV3-7*03 F (see comment) 540 71.89 156/217 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.6] PV## out-of-frame + Low V-REGION identity (71,89% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3242 JY8QFUQ01DRIZW No results 3243 JY8QFUQ01C8XFG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3244 JY8QFUQ01CLCPQ No results 3245 JY8QFUQ01DAFCH No results 3246 JY8QFUQ01BLMEC No results 3247 JY8QFUQ01DRSFS unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 945 93.09 202/217 nt 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattGggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaaggggcaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgcctggtccagggcttcttcccccg 3248 JY8QFUQ01AXBY3 No results 3249 JY8QFUQ01CFQIN No results 3250 JY8QFUQ01BUZB4 unproductive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CVGRSSKGITIS#YW out-of-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtggggagatcgtcaaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 3251 JY8QFUQ01AHBZ8 No results 3252 JY8QFUQ01DV3Q9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3253 JY8QFUQ01BK1U9 No results 3254 JY8QFUQ01CELX5 No results 3255 JY8QFUQ01A2ZLE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ggctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcatcgtttcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3256 JY8QFUQ01BWZOD No results 3257 JY8QFUQ01DCAPL productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3258 JY8QFUQ01BJI1W No results 3259 JY8QFUQ01C70X6 productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 9 8.8.9 [1.17.38.11] CAWGPNGADYW in-frame + ctctggattcaccttcggtaactcaaccatgaactgggtccgccaggctccagggaaggggctggaatggctgtcatatcttagtagtggtggtgatgtcaaatactacgcaggctctctgaagggccgattcaccatctccagagacagtgccaggaactcactgtatctgcaaatgaacagcctgacagacgaggacacggccgtatattactgtgcatgggggcccaacggcgccgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 3260 JY8QFUQ01CGYIW No results 3261 JY8QFUQ01B1HQ0 No results 3262 JY8QFUQ01CLXYH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 746 82.79 178/215 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found Low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3263 JY8QFUQ01DXDU5 productive Homsap IGHV4-39*02 F (see comment) 771 83.64 184/220 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARHLTNSDVVHHFYSGVDVW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggtgcctccatcagtaatgataattatttctgggcctgggtccgccagtccccagggaagggtctgcagtggattggcagtatgtattatagtgggggcaccttttacgacccgtccctcaagggtcgaatcaagttgtccgttgacgtgtcgaagagccacttcctcctgaacctgacctctgcgaccgccgcagacacggctgtctattactgtgcgaggcatttgaccaactcagatgtggtccatcacttctactccggagtagacgtctggggcctcgggaccacggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3264 JY8QFUQ01CXO2O unknown (see comment) Homsap IGHV3-48*01 F 1017 96.77 210/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtggctactgggggccagggtaaccccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 3265 JY8QFUQ01BWUVE No results 3266 JY8QFUQ01CL3UU productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggttcagggcttcttccccca 3267 JY8QFUQ01C8IAO No results 3268 JY8QFUQ01DV057 productive Homsap IGHV3-48*04 F 991 94.98 208/219 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CARDAGGSGWYLYYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtagtactaccatatactacgcagactctgtgaagtgccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacggcctgagagccgaggacacggctgtttattcctgtgcgagagatgcggggggcagtggctggtacctttactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3269 JY8QFUQ01AIC3H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctgacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3270 JY8QFUQ01CRFZZ No results 3271 JY8QFUQ01A6ZI7 productive Homsap IGHV3-30*19 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKSPSQVGYYLDCW in-frame + tctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3272 JY8QFUQ01DRGJF No results 3273 JY8QFUQ01B5WDT No results 3274 JY8QFUQ01BKKCI unproductive Homsap IGHV3-48*01 F 859 88.89 192/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + tctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 3275 JY8QFUQ01A56F5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDMGGDYYIFHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ttctggattctcctttagcaactatgccctgggCctgggtccgccaggctccagggaaggGggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3276 JY8QFUQ01AJL7I productive Homsap IGHV4-61*02 F 1005 95.45 210/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + ctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3277 JY8QFUQ01CXEVJ productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3278 JY8QFUQ01CU80D unproductive Homsap IGHV3-48*03 F 810 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDPREGA#FFDYW out-of-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccagattccagggaaggggctggagtgggtagggtacattagtagtactgggaataccatatattacgcagactctgtgaggggccgattcaccatctcccgcgacattgccgaaaattcactgtatctgcaaatgaatagcctgacacccgacgacacggctgtctattactgcgcgagagatccccgagagggggcaccttctttgactactggggccggggaaccctggtcaccgtctcctctgcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3279 JY8QFUQ01AZJ1G unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGPL# out-of-frame + ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggcccactggggcccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 3280 JY8QFUQ01AEQU4 productive (see comment) Homsap IGHV4-39*03 F 902 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'TT' (2 nucleotides at position 71 to 72 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagccccccagggaagggttTTggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3281 JY8QFUQ01A0TRH No results 3282 JY8QFUQ01A1D4S No results 3283 JY8QFUQ01AO2QZ No results 3284 JY8QFUQ01BE4X5 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 976 92.89 209/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame - ctccgggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3285 JY8QFUQ01BCUCE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 89 58.57 41/70 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccc 3286 JY8QFUQ01AXDJ6 No results 3287 JY8QFUQ01CKBC1 No results 3288 JY8QFUQ01BTHHB No results 3289 JY8QFUQ01DN5IU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 193 93.18 41/44 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found ctctggattcaccttcagcaagtatgccatgagctgggtccgcc 3290 JY8QFUQ01CH3N0 No results 3291 JY8QFUQ01A764V No results 3292 JY8QFUQ01BDU33 unknown (see comment) Homsap IGHV3-7*02 F (see comment) 226 57.59 110/191 nt 57.07 109/191 nt 8 8 X 8.8.X [1.16.30.X] null + No rearrangement found stop codons Low V-REGION identity (57,59% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaagggctggagtgggtggccaacataatgccagatggagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatggcaacgtggtcgtcgcatgcctggtccagggcttcttcccca 3293 JY8QFUQ01A38XN No results 3294 JY8QFUQ01DU0GI productive (see comment) Homsap IGHV3-48*02 F 781 85.45 182/213 nt 84.04 179/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-13*01 F 1 7 7 13 7.7.13 [1.17.37.11] CATARKYTINWRDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'GGC' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggattgacttcaatagctttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtggcgtacatcagttgGGCcagtacaaacatattccacgcagagtctttcagggccgattcaccatctccagagacgatgcgaaggagtcactctatttgcaaatggaccgcctgacacacgacgacacggcagtatattactgtgcgacggcccgaaaatataccatcaattggagggactattggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3295 JY8QFUQ01CZP1B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3296 JY8QFUQ01DFS61 unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F (see comment) 224 83.87 52/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFFP##YSGLDVW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity) tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccacnactactccggtttggacgtctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3297 JY8QFUQ01BB1ZL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 3298 JY8QFUQ01CBDNC unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 709 85.13 166/195 nt 84.62 165/195 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) tgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg 3299 JY8QFUQ01CX1TO productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 639 93.79 136/145 nt 93.1 135/145 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [1.8.31.11] CARRDVGLHAFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 53 in the user submitted sequence), (do not cause frameshift) ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 3300 JY8QFUQ01B71SX No results 3301 JY8QFUQ01B1AO1 No results 3302 JY8QFUQ01BLTJO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3303 JY8QFUQ01DNOF4 No results 3304 JY8QFUQ01AW13H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3305 JY8QFUQ01BWDIP productive (see comment) Homsap IGHV1-24*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3306 JY8QFUQ01DV0CS productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1038 98.6 211/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3307 JY8QFUQ01CYTUQ No results 3308 JY8QFUQ01DMRDJ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found cctccggattcacctttagtagtttctggatgcactgggtccagggcttcttcccca 3309 JY8QFUQ01A0APK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 121 54.48 73/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3310 JY8QFUQ01AIPBE No results 3311 JY8QFUQ01CAL51 No results 3312 JY8QFUQ01B27X3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3313 JY8QFUQ01DH22E No results 3314 JY8QFUQ01DR9HF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3315 JY8QFUQ01BSPXT productive Homsap IGHV3-7*01 F 837 87.56 190/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3316 JY8QFUQ01CH3RZ unproductive (see comment) Homsap IGHV4-4*07 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 8 7 18 8.7.18 [1.17.38.11] CTKM*GHWAVTRTGDTLIIW in-frame + stop codons ctctggtgactccatcaatactttctactggagctgggtccggcagtccgccgggaagggactggagtggattgggcgtatctattccagtggggacaccaactacaacccctccctcaggagtcgagtcaccatgtcaatagacacgtccaggagtcagttctccctgaggctgacgtctgtgagcgccgcggacacggccatatattactgtacaaagatgtagggccactgggcagtgactcgtactggggatactcttattatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 3317 JY8QFUQ01B6JM9 No results 3318 JY8QFUQ01APNUG productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 3319 JY8QFUQ01ARXPV No results 3320 JY8QFUQ01AWH7M productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3321 JY8QFUQ01ARM46 No results 3322 JY8QFUQ01AHRGK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccaattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 3323 JY8QFUQ01BF675 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3324 JY8QFUQ01DBSK6 unproductive Homsap IGHV4-59*02 F 894 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGGSGGALLESDPG#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 20 to 22 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 107 to 118 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagaggtgggtccggtggggccctactggaatctgatccggggactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3325 JY8QFUQ01BVFXH No results 3326 JY8QFUQ01CRKC4 No results 3327 JY8QFUQ01CA3C0 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3328 JY8QFUQ01BVMA3 No results 3329 JY8QFUQ01CH3TH productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3330 JY8QFUQ01BXY7M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtagtttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3331 JY8QFUQ01DE0O0 productive Homsap IGHV4-61*03 F, or Homsap IGHV4-61*08 F 861 88.18 194/220 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD5-24*01 ORF 1 10 7 19 10.7.19 [1.17.38.11] CARLRRMVPVSTYYYHSLDVW in-frame + ctccggtgcctccgtcaactatgatgcttactactggagttggatccggcagcccccagggagtccactggagtggattgggtatgcccatcacagtgggagcaccaactacaacccctccctcaggagtcgagtcaccatttcagttgacccgtcgaagaataacttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacttcgaaggatggttccagtttcgacctactactaccacagtttggacgtctggggccaagggaccacggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3332 JY8QFUQ01AJX06 No results 3333 JY8QFUQ01BBTR2 unknown (see comment) Homsap IGHV3-13*01 F (see comment) 356 67.44 116/172 nt 8 7 X 8.7.X [1.17.24.X] null + No rearrangement found stop codons Low V-REGION identity (67,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3334 JY8QFUQ01CH6O1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.37.11] CAREGGGAVRRK#YFDYW out-of-frame - in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaggggactctgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3335 JY8QFUQ01DEWRA productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctcctccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3336 JY8QFUQ01BIQ9H unknown (see comment) Homsap IGHV3-11*01 F (see comment) 707 80.28 175/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagcgacaactacatgagctggatccgccaggctccagggaaggggctggattgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcacttttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3337 JY8QFUQ01DK7UI No results 3338 JY8QFUQ01DA2I2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 840 88.32 189/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 12 8.8.12 [0.17.38.11] CAKQTVASSSFDFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tggatacacttttgccttctactggatcgcctgggtgcgccaggagcccgggaaaggcctggagtggatgggaatgatctatcctgatgactctagaagcagatatagtccgtccttccaaggccaggtcaccatgtcagtcgacaagtccatcgacaccgcctacctgcaatggagtagcctgaaggcctcggacaccgccacttattactgtgcgaaacaaacggttgcttcatcttcctttgacttttggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3339 JY8QFUQ01C18QQ No results 3340 JY8QFUQ01CGLB0 No results 3341 JY8QFUQ01CZNP8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagcctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3342 JY8QFUQ01CIF07 No results 3343 JY8QFUQ01C09L3 No results 3344 JY8QFUQ01ALPU7 No results 3345 JY8QFUQ01CCDML productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3346 JY8QFUQ01DRFQG productive (see comment) Homsap IGHV4-39*02 F 839 86.88 192/221 nt 86.43 191/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctGggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 3347 JY8QFUQ01BSHAA No results 3348 JY8QFUQ01AP9X6 No results 3349 JY8QFUQ01BQ4Y6 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 3350 JY8QFUQ01CLJK6 productive Homsap IGHV3-72*01 F 975 93.27 208/223 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD4-11*01 ORF 1 8 10 13 8.10.13 [1.17.38.11] CVRGLQSNYYGMDVR in-frame + ctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaaaattaacagttacagtacagaatatgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaatttactgtatctgcaaatgaacagcctgagaagcgaggacacggccgtatattactgtgttagaggcctacagagtaattactacggtatggacgtcaggggccaggggaccacggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 3351 JY8QFUQ01C186Z productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-23*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CAKVGSTVVGDFDYW in-frame + ctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagtagggtcgacggtggtaggggactttgactactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 3352 JY8QFUQ01AYOID productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggaacacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3353 JY8QFUQ01CKTZ9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 320 72.44 92/127 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (72,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccagggaaggggttggagtgggtctcatctattagtactagtggtcatcgcctgcctggtccagggcttcttccccca 3354 JY8QFUQ01BNVVK unproductive Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD3-3*01 F 1 8 7 X 8.7.X [1.17.38.11] CACGHMRDGYDVW# out-of-frame + in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctgggggcccaagggacaaaggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 3355 JY8QFUQ01B09D0 productive Homsap IGHV3-11*01 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3356 JY8QFUQ01C7O3Y No results 3357 JY8QFUQ01A6T30 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 3358 JY8QFUQ01DG9SE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtCaaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3359 JY8QFUQ01DTUR2 productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3360 JY8QFUQ01A3HCE productive Homsap IGHV3-11*01 F 823 87.04 188/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame + tctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3361 JY8QFUQ01COCTJ productive Homsap IGHV1-18*01 F 1002 96.73 207/214 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [0.17.38.11] CARGALGGYSYGMDVW in-frame - aggttacacctttaccagctatggtattagctgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttacaatggtaacacaaactatgcagagaagctccagggcagagtcaccatgaccacagacagatccacgagaacagcctacatggagttgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggggctctagggggctactcctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 3362 JY8QFUQ01DV1Y1 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 336 72.73 96/132 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DV1Y1 ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (72,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcccctttagtatgtattggatgtattgggtccgccaagctcccgggaaggggccggtatgggtcgcacgtatcagtaatgatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3363 JY8QFUQ01CLZRS productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3364 JY8QFUQ01CZ0HC No results 3365 JY8QFUQ01ANAO8 No results 3366 JY8QFUQ01DKIYF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 3367 JY8QFUQ01AVEXE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 585 92.65 126/136 nt 91.91 125/136 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 X 16 8.X.16 [1.1.35.11] CVRYDYSRLHRSNYFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 81 nucleotides (from position 32 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcatcagttatggcatgaactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 3368 JY8QFUQ01AT5GR No results 3369 JY8QFUQ01AER6E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 492 84.06 116/138 nt 83.33 115/138 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (84,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca 3370 JY8QFUQ01BEQ83 productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag 3371 JY8QFUQ01CAR29 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 993 96.26 206/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccag 3372 JY8QFUQ01AV54J No results 3373 JY8QFUQ01CGQFF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagcatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3374 JY8QFUQ01CWZUH No results 3375 JY8QFUQ01A62R0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3376 JY8QFUQ01AQVZH No results 3377 JY8QFUQ01CNXIB No results 3378 JY8QFUQ01BJWBZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + tccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 3379 JY8QFUQ01DK8UH productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtcagggcttcttccc 3380 JY8QFUQ01AOGMF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 3381 JY8QFUQ01A1LNA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtctagggcttcttccccca 3382 JY8QFUQ01BX9J5 No results 3383 JY8QFUQ01CRWBY No results 3384 JY8QFUQ01BLPQB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 471 94.29 99/105 nt 93.33 98/105 nt 8 8 X 8.8.X [1.16.1.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggagtagtactgacatatact 3385 JY8QFUQ01DGLN7 No results 3386 JY8QFUQ01DT1VZ No results 3387 JY8QFUQ01BI9ZZ No results 3388 JY8QFUQ01DT88Q unproductive (see comment) Homsap IGHV4-61*01 F 830 86.43 191/221 nt 85.52 189/221 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARAGGWTPYFDSW in-frame - stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'T' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactaTgcttggggccaccaacctgcccccctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaAgttttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggaccccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3389 JY8QFUQ01AXAUU No results 3390 JY8QFUQ01C6VR6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3391 JY8QFUQ01CH3X2 productive Homsap IGHV3-48*03 F 825 88.15 186/211 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [X.17.38.11] CARDKGWSGYGMDVW in-frame + attcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 3392 JY8QFUQ01DD3NU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 3393 JY8QFUQ01DSA0R unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 117 54.76 69/126 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 3394 JY8QFUQ01DDMLQ No results 3395 JY8QFUQ01BLBRH unproductive Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F (see comment) 660 77.13 172/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 10 X 8.10.X [1.17.38.11] CAGLLSHLT#W out-of-frame + Low V-REGION identity (77,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgatgtggtcggcttcggggcttacacaatgacttggttccgcttgcctccagggaggggcctggaattggtaggtttcatcaggagcacgggaaacggtgggacaacagagtacgccgcgtctgtgagaggcagagtcttcatctcaagagatagatccaacaatgtcgcctatctacaaatgaacaatctgaagaccgaggacaccgccatatattattgcgctggactcctttcccatttgacatatggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3396 JY8QFUQ01DFF6W unknown (see comment) Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagatttacggattactggggcccagggaaccctggtcaccgtttgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtccgcatgcctggtccagggcttcttccccca 3397 JY8QFUQ01DPAO2 productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3398 JY8QFUQ01DQRIP No results 3399 JY8QFUQ01CW5LL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + tctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtcaccgtctcctcaccatccccgaccagcccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttcccc 3400 JY8QFUQ01DMBMA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + tctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3401 JY8QFUQ01DNDYD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 388 87.13 88/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcagctattagtggtagggtgttgaca 3402 JY8QFUQ01AVUV9 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtgggggggaccaggggaccctggtcaccggtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3403 JY8QFUQ01CVSFA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 856 90.0 189/210 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [X.17.38.11] CTRDIGGRYSYW in-frame + ttcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3404 JY8QFUQ01CJJOB productive (see comment) Homsap IGHV3-7*03 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggattcacttttagtgactattggatgagttgggtccgccaggctccagGggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3405 JY8QFUQ01AKAN3 productive (see comment) Homsap IGHV3-11*01 F 925 92.96 198/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagaaccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3406 JY8QFUQ01CXXIO productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01CXXIO ; 7 AA in Homsap_IGHV3-53*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ttcggggttcaccgtcagtagcaagtacatgacctCgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcagtgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3407 JY8QFUQ01DE4P9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctatatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3408 JY8QFUQ01AIVPA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatTgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 3409 JY8QFUQ01CLL6Y productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); tttctggaGtacagttttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3410 JY8QFUQ01C2IMN No results 3411 JY8QFUQ01A35DO unproductive (see comment) Homsap IGHV4-61*01 F 947 92.31 204/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacacttatgacagcccgtggggacaggggacccctggtcagccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3412 JY8QFUQ01CY6QY No results 3413 JY8QFUQ01DA7X2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 87.67 192/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found gcctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3414 JY8QFUQ01DO5F5 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1071 99.54 216/217 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame + ttctggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3415 JY8QFUQ01CXQMU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + tctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3416 JY8QFUQ01A9YP9 No results 3417 JY8QFUQ01APABC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccggaagtagttattattggggctggattcgccagTcccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc 3418 JY8QFUQ01B4IUJ No results 3419 JY8QFUQ01ATC1E No results 3420 JY8QFUQ01ABR6O No results 3421 JY8QFUQ01B6YN6 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 3422 JY8QFUQ01DNCXN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*02 F 1 8 8 16 8.8.16 [1.16.38.11] CAKDPQQLLEDINWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) ctctggattcacctttcgcagctatgccatgagctgggtccgccaggctcaggaagggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccggttcaccatctccagagacaacgccaggaacacattttatctgcaaatggacagcctcagagccgaggacacggccgtctattactgtgcgaaagatcctcagcagttattggaagacataaactggttcgacccctggggccagggcacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 3423 JY8QFUQ01DVO9C unproductive (see comment) Homsap IGHV3-15*04 F 1011 95.07 212/223 nt 93.72 209/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTGGWN*L##W out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttGggccgtattgcCaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggttggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccagtcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3424 JY8QFUQ01CIQ3V productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 644 93.84 137/146 nt 93.15 136/146 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [1.8.31.11] CARRDVGLHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 54 in the user submitted sequence), (do not cause frameshift) gttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 3425 JY8QFUQ01DLASW No results 3426 JY8QFUQ01A8HR6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-3*01 F 2 8 7 10 8.7.10 [1.17.38.11] CARNRWSGFDVW in-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) tgtctggtggctccctcacaaattactattacagttggatacggcagaccccagggagaggactggagtggattgcatatatctatgcccgtggcaataccaactacaatccctcctttaggagccgggccaccatatcagtcgacacggctaagaaccagttttccctggagttgaattctgtgaccgcagcggacacggccgtttattactgtgcgagaaaccggtggagcggctttgatgtctggggcccagggacactcatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3427 JY8QFUQ01CTLVA unproductive Homsap IGHV4-61*02 F 848 86.88 192/221 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARGMATIKRS#FDPW out-of-frame + tctctggtggctccatgaggagtggaattaattcctggacatggatccggcagcccgccgggaagggactggagtggattgggcgtatctatatcaatggagacaccaactacaatccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3428 JY8QFUQ01BPHVF unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaaggaacctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccctcgcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3429 JY8QFUQ01AS5EL productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame + tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 3430 JY8QFUQ01AHAEV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 464 91.74 100/109 nt 90.83 99/109 nt 8 8 X 8.8.X [1.16.2.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcacatttagcaactatgccatgagctgggtccgccaggctccagggaagggccggagtgggtctcagctattactggtcttgatggtagaacattctacgc 3431 JY8QFUQ01BMQPR No results 3432 JY8QFUQ01CJAJA No results 3433 JY8QFUQ01DWP1K unproductive Homsap IGHV3-30*10 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CLAEVEAD#FDNW out-of-frame - Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaaggggActagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3434 JY8QFUQ01AOD6D No results 3435 JY8QFUQ01AR4UO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3436 JY8QFUQ01B5293 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGIVGETFFDHW in-frame + ctctggattcacctttaataactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtactagtggtagtcacactaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagggatagtgggagaaactttctttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 3437 JY8QFUQ01BII7Q No results 3438 JY8QFUQ01AR3J4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3439 JY8QFUQ01DXCD1 No results 3440 JY8QFUQ01DQAM2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - ctctggagttcagccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3441 JY8QFUQ01CDKOP No results 3442 JY8QFUQ01B8A2A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3443 JY8QFUQ01AMBWC productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3444 JY8QFUQ01ALCRS No results 3445 JY8QFUQ01BMGV5 No results 3446 JY8QFUQ01CCPK9 No results 3447 JY8QFUQ01AV0YA unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggaacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3448 JY8QFUQ01B2MRJ No results 3449 JY8QFUQ01CV95R unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 280 82.14 69/84 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-13*01 F 3 X X X X.X.X [X.X.28.11] CVKIERAAIGTTLRT# out-of-frame + Low V-REGION identity (82,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaagatcgaaagggcagcaattggtactactttgagaactgggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3450 JY8QFUQ01BWP0D No results 3451 JY8QFUQ01CMFQ9 No results 3452 JY8QFUQ01BRPAV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3453 JY8QFUQ01BBXWK No results 3454 JY8QFUQ01AYHQQ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 979 93.69 208/222 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame + tctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3455 JY8QFUQ01CKKEJ No results 3456 JY8QFUQ01DO5OF productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3457 JY8QFUQ01BCDBF No results 3458 JY8QFUQ01CIV7S productive (see comment) Homsap IGHV3-7*01 F 880 90.61 193/213 nt 89.2 190/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 7 14 7.7.14 [0.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctggatttactttaacaactattggatgacctgggttcgccaggctccagggaagggctggcaatgggtggccaacataaacaacatggaggtgaaacgtactatCgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3459 JY8QFUQ01CRXS1 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 867 89.72 192/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 7 11 8.7.11 [1.17.38.11] CARDRQSWGIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3460 JY8QFUQ01AE5BH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 3461 JY8QFUQ01CMJK0 No results 3462 JY8QFUQ01B3P8Z productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3463 JY8QFUQ01BUVIO No results 3464 JY8QFUQ01AVY3P No results 3465 JY8QFUQ01CD0J1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3466 JY8QFUQ01AVQLE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3467 JY8QFUQ01DCZ30 No results 3468 JY8QFUQ01A77JN No results 3469 JY8QFUQ01DDF5Y productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3470 JY8QFUQ01B9X9X productive (see comment) Homsap IGHV3-72*01 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.16.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3471 JY8QFUQ01C82CC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.16.38.11] CARGRIVSVGMSGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaagggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3472 JY8QFUQ01AJCZV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3473 JY8QFUQ01A0GMU No results 3474 JY8QFUQ01B5U1N productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARMGYGYRGIYFFDYW in-frame - cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagaatgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 3475 JY8QFUQ01AFC6N unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDLYGADDL## out-of-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccggctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 3476 JY8QFUQ01C8SMK No results 3477 JY8QFUQ01CSNZ8 No results 3478 JY8QFUQ01DUM9Y productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 3479 JY8QFUQ01CRXX8 No results 3480 JY8QFUQ01DEFOC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3481 JY8QFUQ01C5EQN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 558 72.81 158/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (72,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3482 JY8QFUQ01BUTXF No results 3483 JY8QFUQ01AOO53 No results 3484 JY8QFUQ01AF8ND productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSAPWNDHW in-frame + tctctggtggctccatcagcagcggttattactactggagctggatccggcagcccgccggggagggactggagtgggttgggcgtatctctgccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatatcagtgaacacgtccaagaaccagttctccttgaggctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagacaaggggacagtagtgctccctggaatgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3485 JY8QFUQ01BIHMA No results 3486 JY8QFUQ01CGWZP productive (see comment) Homsap IGHV3-7*02 F 899 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CTRSSNSAYDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctctggattcacgtttagtaacagttggatggctgggcccgccaggctccagggaagggctggagtgggtggccagcacaaaccaagatgcaagtgagaaaaagtatgtggactctgtgaggggccgattcaccatctcaagagacaacgccaagaactcactgtatttacaaatgaacagcctaagagccgaggacacggctttatatttctgtacgaggtccagtaacagcgcttatgactattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3487 JY8QFUQ01AAQKM No results 3488 JY8QFUQ01AEYEY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1014 95.91 211/220 nt 95.45 210/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3489 JY8QFUQ01A6RSK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 302 96.88 62/64 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found ctctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaaggggctg 3490 JY8QFUQ01C0RM5 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1010 95.48 211/221 nt 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 2 8 10 10 8.10.10 [0.17.38.11] CTTLPWEPLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctggattcactttcagtaatgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaactagaactgatggtgagacaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcCaaaaaacacgttgtttcttcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtaccactcttccttgggagcctctcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3491 JY8QFUQ01BY1TX No results 3492 JY8QFUQ01C88VO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3493 JY8QFUQ01DVH7K unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame + stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag 3494 JY8QFUQ01DJBZ7 No results 3495 JY8QFUQ01B5YDP unproductive (see comment) Homsap IGHV3-66*02 F 854 88.84 191/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-3*01 F 1 8 7 19 8.7.19 [1.17.38.11] CATTPAGEPIGSRQ*WF*YLG in-frame + stop codons cctctggactcatcgtcagtggcagctacatgagttgggtccgccaggctcctgggaaggggctagaatggatctcagttatttatagcgatggtagcgcatactacgcagagtccgtgaagggccggttcaccatctccagagacgcttctaagaacacagtttatcttctgatgaacaacctgagaactgaggacacggctgtatattactgtgcgactacccccgcgggggagcccatcggatcccgacaatgatggttttaatatttgggggcccaagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgngcctcctgagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa 3496 JY8QFUQ01BGJ03 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaagggcttcttcccccag 3497 JY8QFUQ01BIMRE No results 3498 JY8QFUQ01A3ZWX productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3499 JY8QFUQ01CGAYM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKQKHSYGYYFDQW in-frame - ctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3500 JY8QFUQ01B4H2V productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3501 JY8QFUQ01BOBM8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggaggggcgtggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 3502 JY8QFUQ01C51YK No results 3503 JY8QFUQ01CXKTJ No results 3504 JY8QFUQ01DMIAX No results 3505 JY8QFUQ01AB42J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3506 JY8QFUQ01AQQHX No results 3507 JY8QFUQ01AVFZY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3508 JY8QFUQ01BGC21 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.16.38.10] CAKSPLSVAGTRQNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaagggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcct 3509 JY8QFUQ01DE44E productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [2.17.37.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) gtctctggtgtctccatcagtagttcctactggagttggatccggcagGcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3510 JY8QFUQ01AEQ4Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3511 JY8QFUQ01DW8OU No results 3512 JY8QFUQ01CR4UL No results 3513 JY8QFUQ01BK72L No results 3514 JY8QFUQ01B6617 No results 3515 JY8QFUQ01DLOAA productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaaggGgccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3516 JY8QFUQ01DCFM0 No results 3517 JY8QFUQ01A4L2D No results 3518 JY8QFUQ01APPM5 No results 3519 JY8QFUQ01BMMXG No results 3520 JY8QFUQ01DEN0P No results 3521 JY8QFUQ01B4P0Q No results 3522 JY8QFUQ01AV67L No results 3523 JY8QFUQ01C7T8Q No results 3524 JY8QFUQ01COB96 No results 3525 JY8QFUQ01CCIZW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt 86.7 189/218 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'C' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'AGGA' (4 nucleotides at position 199 to 202 in the user submitted sequence), (cause frameshift); cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatCgaacaagcctaggggccagAGGAgcgacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3526 JY8QFUQ01A2P8W unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.16.38.11] CVRDRDFLWGSYRLQLEY## out-of-frame + in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaaaaggggctggagtgggtctcaggaattagtgcgaatggtggtagtataaattatgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacattgtttctgcaaatgaatagcctgagagccgaagacacggccgtatattactgtgtgagagatcgcgatttcctgtgggggagttatcgtcttcaacttgaatattggggccaaggaaccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3527 JY8QFUQ01A1485 No results 3528 JY8QFUQ01CXERX unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 3529 JY8QFUQ01A7A3Y No results 3530 JY8QFUQ01AGGIL productive Homsap IGHV3-7*01 F 933 91.82 202/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [2.17.38.11] CSRHGGYTRLYNQNVYLDYW in-frame - ggcctctggattcacatttagcaacttttggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaaaataaacccagacggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgagactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3531 JY8QFUQ01CYTT3 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 13 7.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) cctctggatcaccttggttattgatggcatgagctggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3532 JY8QFUQ01B4JGT No results 3533 JY8QFUQ01CPSCG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 491 84.56 115/136 nt 83.82 114/136 nt 8 8 X 8.8.X [1.16.11.X] null + No rearrangement found Low V-REGION identity (84,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 3534 JY8QFUQ01CWIF1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame - cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccc 3535 JY8QFUQ01ANZNP productive Homsap IGHV3-9*02 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD3-9*01 F 3 8 8 11 8.8.11 [1.17.38.11] CGKDMRLGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgaaagttgaggacacggccatgtattactgtggaaaagatatgcgactgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3536 JY8QFUQ01A8U8B No results 3537 JY8QFUQ01CCQKT No results 3538 JY8QFUQ01AURV3 No results 3539 JY8QFUQ01BDTBC unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.37.11] CAREGGGQFVG##YFDYW out-of-frame - stop codons in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaggggactctgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcgggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3540 JY8QFUQ01CNTXZ No results 3541 JY8QFUQ01C9T65 productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3542 JY8QFUQ01B9OYU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3543 JY8QFUQ01A88IP productive Homsap IGHV3-9*01 F 968 94.04 205/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3544 JY8QFUQ01CCSP4 No results 3545 JY8QFUQ01APOI8 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 85 51.49 69/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcacctttaacctctatgtcatgcactggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3546 JY8QFUQ01ARWSX No results 3547 JY8QFUQ01BBZ9B No results 3548 JY8QFUQ01CBJ3B No results 3549 JY8QFUQ01BA6WI productive Homsap IGHV4-39*03 F 920 90.91 200/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] CTREGPYYYGMDVW in-frame + tctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3550 JY8QFUQ01DRIVX productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3551 JY8QFUQ01CR8FZ No results 3552 JY8QFUQ01B9CQM No results 3553 JY8QFUQ01B2Q8V No results 3554 JY8QFUQ01B9ZY4 No results 3555 JY8QFUQ01DH2JR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 917 92.09 198/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDQSLGMPEAFDIW in-frame + ctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3556 JY8QFUQ01DQXN3 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame + ctctggattcacttttagcagtttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccaagcatccccgaccagccccgaaggtcttcccagctgacgctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 3557 JY8QFUQ01AU1X2 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [2.17.38.11] CARASTLRYLDRW in-frame - gtctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3558 JY8QFUQ01DG3GX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaAGggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3559 JY8QFUQ01BN2A0 No results 3560 JY8QFUQ01ALROO unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaact 3561 JY8QFUQ01DCAFK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccCctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3562 JY8QFUQ01BE1SO unknown (see comment) Homsap IGHV4-30-2*04 F, or Homsap IGHV4-34*01 F or Homsap IGHV4-34*02 F or Homsap IGHV4-34*08 F or Homsap IGHV4-34*12 F or Homsap IGHV4-34*13 F or Homsap IGHV4-38-2*01 F or Homsap IGHV4-38-2*02 F or Homsap IGHV4-39*01 F or Homsap IGHV4-39*05 F or Homsap IGHV4-59*04 F or Homsap IGHV4-59*05 F or Homsap IGHV4-59*08 F 418 91.92 91/99 nt X X X X.X.X [X.X.33.X] null - No rearrangement found stop codons ctatggagtcgagtcaccatatgagtagacacctccaagaaccagttctccctgaaggtgagctctgtgatcgccgcagacacggctgtgtattactgtgcgagacgtaagggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3563 JY8QFUQ01DW4KO unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 89 58.57 41/70 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccc 3564 JY8QFUQ01AYH21 No results 3565 JY8QFUQ01DPK2Q productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3566 JY8QFUQ01C608B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3567 JY8QFUQ01BHUTE No results 3568 JY8QFUQ01AYYZI No results 3569 JY8QFUQ01B393V No results 3570 JY8QFUQ01AXYLH No results 3571 JY8QFUQ01AQUPN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1006 97.18 207/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [X.17.38.11] CVVQILGATIDYW in-frame + ggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3572 JY8QFUQ01BB2PN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaactca 3573 JY8QFUQ01CWLL0 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag 3574 JY8QFUQ01BGMHI No results 3575 JY8QFUQ01CG65B No results 3576 JY8QFUQ01CWI6C productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 768 82.96 185/223 nt 82.51 184/223 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARHRSFGVIIVNYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); atttcccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatCggggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3577 JY8QFUQ01BAR2U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame + ctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagcagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3578 JY8QFUQ01C9E4I unproductive Homsap IGHV3-48*01 F 859 88.89 192/216 nt 87.5 189/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.16.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame - in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcttcagtttgagtacttataccatgGaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3579 JY8QFUQ01BKVA2 productive Homsap IGHV3-7*01 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [2.17.38.11] CARGSYWHYDTFGDYW in-frame - gcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 3580 JY8QFUQ01C2JLD productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3581 JY8QFUQ01BNZDJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 377 75.94 101/133 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (75,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 3582 JY8QFUQ01A3HY6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 825 86.36 190/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccaggggaaggggctgagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3583 JY8QFUQ01CMS5Z No results 3584 JY8QFUQ01ANNT6 productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.16.38.11] CARDSVPRASEAAYYFDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtatttattctatgcattgggtccgccaggccccaggcaagggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacggctgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3585 JY8QFUQ01DNX9B unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CARGIVVYSESESPTTPK#DYW out-of-frame + tggatacaccttcagcaacttctatatatattgggttcgacaggcccctggacaagggcttgattacataggagtattcaaccctagtggtggtaacaccaggtacgcacagaagttccaggacagagtcaccgtgaccagtgacacgtccacgaacacagtgtacatggagctgagtaggctgagatctgaagacacggccgtgtattactgtgcgagagggatagtggtttactctgaatcggaaagtccgacaaccccgaaaatgactactggggccagggaacccgggtcatcgtctcctcagcttccaccaagggcccatccgtcttccccgtggcgccctgctccaggagcacctccgagagcacagccgcccatgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactcag 3586 JY8QFUQ01C7CBC productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3587 JY8QFUQ01BX1RT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3588 JY8QFUQ01AJX0L No results 3589 JY8QFUQ01AVVL2 No results 3590 JY8QFUQ01C8N0Q No results 3591 JY8QFUQ01C84TZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CSKDTFGREDYW in-frame - gcctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3592 JY8QFUQ01DD1D4 unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 777 83.41 186/223 nt 82.51 184/223 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-9*01 F 3 7 9 X 7.9.X [2.17.38.11] CATDSPTGYYA#FDVW out-of-frame - stop codons Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 27 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) gcctctgggtcgatttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcattttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3593 JY8QFUQ01DBXJG No results 3594 JY8QFUQ01DW47I No results 3595 JY8QFUQ01CCVPU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F (see comment) 133 74.0 37/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaacggtcaccggtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 3596 JY8QFUQ01CS83G unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 3597 JY8QFUQ01DSAWM productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 3598 JY8QFUQ01CJV25 No results 3599 JY8QFUQ01AJSSD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + tctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3600 JY8QFUQ01CJ8QL No results 3601 JY8QFUQ01AYBE9 productive (see comment) Homsap IGHV3-33*03 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3602 JY8QFUQ01CCYFS No results 3603 JY8QFUQ01BGN8C unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 199 78.46 51/65 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found tctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccccc 3604 JY8QFUQ01C03FW No results 3605 JY8QFUQ01BPADK No results 3606 JY8QFUQ01AN937 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARQSEPANNFNDPSRYFFDTW in-frame + Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcccgtgtctccatttccattaatgattactactggggctggatccgccagcccccaggaaagccgctggagtggattgggactgtccattcccttgggtacaattacaacaacccgtccctcaagagtcgactcaccatttccgcagacacgtccaggaatcagatctccctgaaactgacgtctgtgaccgccgcagacacggctgtctatttctgtgcgagacagagcgagcccgccaataacttcaatgacccaagtcgttatttctttgacacttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3607 JY8QFUQ01A2748 No results 3608 JY8QFUQ01A0EII No results 3609 JY8QFUQ01AA9N3 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 363 64.22 131/204 nt 63.73 130/204 nt 8 7 X 8.7.X [1.17.34.X] null + No rearrangement found Low V-REGION identity (64,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3610 JY8QFUQ01DCC4H unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRSGRDGG#WFDSW out-of-frame + in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccCaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggcctggttcgactcctggggccagggaacccgtggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 3611 JY8QFUQ01C0QV3 No results 3612 JY8QFUQ01DNCPQ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 3613 JY8QFUQ01CILSN No results 3614 JY8QFUQ01DNNQS No results 3615 JY8QFUQ01AZWL7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3616 JY8QFUQ01C9XRD productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag 3617 JY8QFUQ01BLQLI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3618 JY8QFUQ01B2DEP unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.37.11] CARRDVGLHAFDL## out-of-frame + in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 127 in the user submitted sequence), (cause frameshift) ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggcaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggcccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3619 JY8QFUQ01DGCW9 No results 3620 JY8QFUQ01AAXZI No results 3621 JY8QFUQ01CVZ9K productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.17.38.11] CAGGRGWLIDYW in-frame - gcctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3622 JY8QFUQ01AYFJR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 103 66.04 35/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcacccgtggtcactgtctcctcagcctccaccaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3623 JY8QFUQ01AZRBP No results 3624 JY8QFUQ01BAC4O No results 3625 JY8QFUQ01BCU1Y productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1009 93.86 214/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CARGSSRGGRSDVNYYELDFW in-frame + tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3626 JY8QFUQ01C2UF8 No results 3627 JY8QFUQ01DHR7Q unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-8*02 F 3 8 7 X 8.7.X [1.17.38.11] CARGSSK#YNWFDPW out-of-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3628 JY8QFUQ01B2B42 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 216 97.78 44/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcaccttcagtagctactggatgcactgggtccccca 3629 JY8QFUQ01DH7E7 No results 3630 JY8QFUQ01BCLRL productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3631 JY8QFUQ01BDV0U unknown (see comment) Homsap IGHV4-61*07 F 853 88.73 189/213 nt 87.79 187/213 nt 8 7 X 8.7.X [2.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 109 to 120 in the user submitted sequence), (do not cause frameshift); tctctgggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3632 JY8QFUQ01CYTFV No results 3633 JY8QFUQ01CCPCW No results 3634 JY8QFUQ01DKHTU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + ttctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3635 JY8QFUQ01AHJC8 No results 3636 JY8QFUQ01AELXN unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3637 JY8QFUQ01ATTEO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3638 JY8QFUQ01BIJ6A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatcccgaccagccccaagggtcttcccgctgagcctcganagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 3639 JY8QFUQ01BIM1I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3640 JY8QFUQ01CQ3VH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQGAIL*WW*LP#FDYW out-of-frame + stop codons ctctggattcacctttagcagaaatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtagtggtggtagcacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttatgcaaatgaacagcctgagagacgaggacacggccgtatattactgtgcgaaagaacaaggggcgatattgtagtggtggtagctgccccatttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3641 JY8QFUQ01BOZDA No results 3642 JY8QFUQ01BGZCE No results 3643 JY8QFUQ01DR19K No results 3644 JY8QFUQ01CWJC9 No results 3645 JY8QFUQ01A2ZZU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 3646 JY8QFUQ01ATX94 productive (see comment) Homsap IGHV3-72*01 F 961 92.79 206/222 nt 92.34 205/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.16.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 3647 JY8QFUQ01CBXG3 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 102 53.03 70/132 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3648 JY8QFUQ01A3DOT No results 3649 JY8QFUQ01BYNF3 productive (see comment) Homsap IGHV3-48*01 F 859 88.89 192/216 nt 87.5 189/216 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.16.38.11] CARASTFYYDGSGYRDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcttcagtttgagtacttataccatgGaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgcttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3650 JY8QFUQ01DC8LT productive (see comment) Homsap IGHV3-7*01 F (see comment) 702 80.65 175/217 nt 79.72 173/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); ctctggattcgtctttactaatcattggatgagAttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatacttttggggactctgtgaaggGgccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3651 JY8QFUQ01ATSDY No results 3652 JY8QFUQ01DFOZG productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaTggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3653 JY8QFUQ01A9M3F No results 3654 JY8QFUQ01CB1JU productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-7*01 F 3 8 7 10 8.7.10 [1.17.38.11] CARDLGGSLDYW in-frame - tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatctcgggggatccttggactattggggccagggaaccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3655 JY8QFUQ01B2NLS No results 3656 JY8QFUQ01COYPY productive Homsap IGHV3-66*02 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CSTPTYCRGGSCSQIFDYW in-frame + ctctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagatttttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3657 JY8QFUQ01C09X0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3658 JY8QFUQ01AQJM4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 775 84.02 184/219 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame + Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3659 JY8QFUQ01AIYRL No results 3660 JY8QFUQ01CUCNH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3661 JY8QFUQ01DCRYR No results 3662 JY8QFUQ01CXWCQ No results 3663 JY8QFUQ01CEP21 productive Homsap IGHV1-2*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARDGISMTLVRGVRPFDYW in-frame + tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaaccctggtcagcgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 3664 JY8QFUQ01DS4NL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 698 80.28 175/218 nt 79.82 174/218 nt 8 8 X 8.8.X [2.17.37.X] null - No rearrangement found Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) gcctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgagggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3665 JY8QFUQ01DF7LK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 194 56.98 98/172 nt 8 8 X 8.8.X [1.17.23.X] null - No rearrangement found ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3666 JY8QFUQ01DE20Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3667 JY8QFUQ01C6LBX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 937 92.24 202/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'TCC' (3 nucleotides at position 18 to 20 in the user submitted sequence), (do not cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); cctgctggattcgacttTCCaggtagctactgGgatgcactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 3668 JY8QFUQ01DDIPQ unknown (see comment) Homsap IGHV3-74*03 F 116 51.34 96/187 nt 8 8 X 8.8.X [1.17.28.X] null + No rearrangement found stop codons tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3669 JY8QFUQ01CFRXM unknown (see comment) Homsap IGHV3-74*03 F 846 88.02 191/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggcagccctggtccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa 3670 JY8QFUQ01CXKD6 No results 3671 JY8QFUQ01DJE9A productive (see comment) Homsap IGHV3-9*01 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARMTLAPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); cctctggattcacctttgatgattatgccatgcactgggtccggcaagcGtccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagtataggctatgcggcctctgtgaagggccgattcaccatctccagagacaacgccaagagctccctgtatctgcaaatgaacagtctaagagctgaggacacggccttatattactgtgcaaggatgacactggctccttttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3672 JY8QFUQ01DNH7I unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 714 85.2 167/196 nt 84.69 166/196 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgcccttgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 3673 JY8QFUQ01DU08B No results 3674 JY8QFUQ01DEA85 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'C' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcGagctgtgagtagtaggggtgAgtaccacacactacgcagacttcgtgaagggccggCgtcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3675 JY8QFUQ01BQEZK No results 3676 JY8QFUQ01DBVT7 No results 3677 JY8QFUQ01CHT9Y unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [0.17.38.11] CARAGGFQ*TSGE##YYNGLDVW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tggatacaccttcagcagttattatatacactgggtgcgacaggAcccccggacaggggcttgagtggatggcaatgatcaacccaagtggtggtagtaccacgtacgcacagaagttccagggcaGgactcatcgtgaccagggacacgtccacgagtagtgtctacatggacctgagtagcctgagatctgaggacacgggcgtctatttctgtgcgagagcgggggggttccagtaaacgtcaggtgaaggactactacaacggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3678 JY8QFUQ01CW4P0 No results 3679 JY8QFUQ01AVTUT No results 3680 JY8QFUQ01AR9R2 No results 3681 JY8QFUQ01DOFOM unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 648 77.42 168/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3682 JY8QFUQ01AV8OV No results 3683 JY8QFUQ01AYE2N No results 3684 JY8QFUQ01CH6ZO No results 3685 JY8QFUQ01CLL92 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3686 JY8QFUQ01A80P5 No results 3687 JY8QFUQ01CMTWR No results 3688 JY8QFUQ01BBJK4 productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*03 F 558 93.7 119/127 nt 92.91 118/127 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 X 12 8.X.12 [0.3.31.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacaccttcaccgtctactatctattctggggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3689 JY8QFUQ01AQ7RC No results 3690 JY8QFUQ01B4WUM No results 3691 JY8QFUQ01AIURT productive Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-21*04 F 959 93.58 204/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 159 75.44 43/57 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3692 JY8QFUQ01A24Q4 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3693 JY8QFUQ01AE8PF No results 3694 JY8QFUQ01A2XPS No results 3695 JY8QFUQ01BWXQJ productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3696 JY8QFUQ01DHQS7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 3697 JY8QFUQ01AU798 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 872 89.77 193/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CARDRQSW#IDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3698 JY8QFUQ01DACXR No results 3699 JY8QFUQ01BH8Y1 No results 3700 JY8QFUQ01CBC50 No results 3701 JY8QFUQ01CR5SB No results 3702 JY8QFUQ01DG06B productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame + tggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 3703 JY8QFUQ01C5K8B unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 215 62.41 83/133 nt 8 6 X 8.6.X [2.17.11.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (6 AA in JY8QFUQ01C5K8B ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (62,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 3704 JY8QFUQ01AQY3A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.16.38.11] CAKGQFGTVMDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggatgggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgttttttattgtgcgaaaggccagtttggtaccgtcatggactattggggccagggaacccaggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3705 JY8QFUQ01A657R No results 3706 JY8QFUQ01CP60I No results 3707 JY8QFUQ01AHSTY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtgactca 3708 JY8QFUQ01DUOE0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3709 JY8QFUQ01CAMZ2 No results 3710 JY8QFUQ01CQXUA No results 3711 JY8QFUQ01B11DM productive Homsap IGHV4-61*02 F (see comment) 785 84.16 186/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame + Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcactagtggtacttactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactaggagcacctattacaacccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3712 JY8QFUQ01BFEAG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CANELGYCSGG# out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3713 JY8QFUQ01CCYR6 productive Homsap IGHV1-3*01 F 849 88.79 190/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3714 JY8QFUQ01BO1K0 No results 3715 JY8QFUQ01BCAH5 No results 3716 JY8QFUQ01CT1JU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3717 JY8QFUQ01AMILA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 594 77.78 154/198 nt 8 8 X 8.8.X [1.17.31.X] null - No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3718 JY8QFUQ01CBOUK No results 3719 JY8QFUQ01DDJ56 No results 3720 JY8QFUQ01ARU4C No results 3721 JY8QFUQ01DIK53 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame - ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 3722 JY8QFUQ01DQSCV productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3723 JY8QFUQ01DKEC5 unknown (see comment) Homsap IGHV3-7*01 F 864 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3724 JY8QFUQ01CUPSC No results 3725 JY8QFUQ01AGL22 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3726 JY8QFUQ01AF9Z6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcaaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3727 JY8QFUQ01A4TVI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD6-6*01 F 2 8 8 17 8.8.17 [2.17.38.11] CVRDLAARPPYYYYGMDVW in-frame - gcctctggatttaccttcagtctctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatctattactagtggtagtcattacatctactacgcagactcagtgaagggccgattcaccatctccagagacgactccaagaactcactgtttctgcagatgaacagcctcagagccgaggacacggctgtttattattgtgtgagggatttggcggctcgtcccccttattattactacggtatggacgtctggggccagggggccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3728 JY8QFUQ01A98RV No results 3729 JY8QFUQ01DTUI2 productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3730 JY8QFUQ01B2WK4 No results 3731 JY8QFUQ01CFEC1 No results 3732 JY8QFUQ01A58YS No results 3733 JY8QFUQ01BNO6U No results 3734 JY8QFUQ01A0B46 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F (see comment) 606 75.7 162/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,70% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3735 JY8QFUQ01DTTWE No results 3736 JY8QFUQ01CAN9N productive Homsap IGHV3-11*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDRGKSGSYGLDHW in-frame + tctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatcgggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3737 JY8QFUQ01BUVJJ No results 3738 JY8QFUQ01C3UP7 No results 3739 JY8QFUQ01ALBVT productive Homsap IGHV4-59*03 F 890 90.7 195/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatccggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaggaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3740 JY8QFUQ01DGY3A No results 3741 JY8QFUQ01AC7VV No results 3742 JY8QFUQ01DPEQC No results 3743 JY8QFUQ01AY97C productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); agtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3744 JY8QFUQ01BOQIM productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag 3745 JY8QFUQ01DB155 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 176 97.3 36/37 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactgg 3746 JY8QFUQ01BLNZS No results 3747 JY8QFUQ01CUIMO No results 3748 JY8QFUQ01CQC4S No results 3749 JY8QFUQ01AD66K productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F 399 86.79 92/106 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 X X 15 X.X.15 [X.X.35.11] CTRELRLAAARDGVDIW in-frame + ctctgggttcaccggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3750 JY8QFUQ01DJ2BM No results 3751 JY8QFUQ01CA7EB unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 620 76.74 165/215 nt 76.28 164/215 nt Homsap IGHJ2*01 F, or Homsap IGHJ4*01 F or Homsap IGHJ4*02 F or Homsap IGHJ5*01 F or Homsap IGHJ5*02 F (see comment) 22 75.0 6/8 nt 8 8 X 8.8.X [1.16.38.0] null + stop codons no junction found Low V-REGION identity (76,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*02 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides). The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 3752 JY8QFUQ01CVHWF No results 3753 JY8QFUQ01DXHW7 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 90 58.33 42/72 nt 56.94 41/72 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagag 3754 JY8QFUQ01BJDTP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3755 JY8QFUQ01AMSEM No results 3756 JY8QFUQ01C3WCI No results 3757 JY8QFUQ01BSG5U unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 606 80.21 150/187 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.16.38.11] DSRNPRV# out-of-frame + Low V-REGION identity (80,21% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) agtggggtccagccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3758 JY8QFUQ01CCRE0 No results 3759 JY8QFUQ01CBEL2 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 3760 JY8QFUQ01DISGH No results 3761 JY8QFUQ01BGWBK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3762 JY8QFUQ01ASXQO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggtttgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3763 JY8QFUQ01A8ODQ No results 3764 JY8QFUQ01A4CAM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 3765 JY8QFUQ01CB9SZ productive Homsap IGHV3-11*01 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRWVWGYSYGSVSYYFEYW in-frame + tctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggtgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 3766 JY8QFUQ01CMDKZ No results 3767 JY8QFUQ01A8XAD No results 3768 JY8QFUQ01BB890 No results 3769 JY8QFUQ01C8BMK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3770 JY8QFUQ01AMDD8 No results 3771 JY8QFUQ01C1UWI productive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 3772 JY8QFUQ01BEU4Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3773 JY8QFUQ01ARIHM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtaAtctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3774 JY8QFUQ01BQ0Z3 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 669 79.44 170/214 nt 78.97 169/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'GG' (2 nucleotides at position 122 to 123 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactcccgtgagGGggtcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 3775 JY8QFUQ01AYPZ6 No results 3776 JY8QFUQ01DXB21 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 2 8 7 X 8.7.X [1.17.38.11] CARAPRTATLLDP#W out-of-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgaccccgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3777 JY8QFUQ01A48DI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3778 JY8QFUQ01DSET8 unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*02 F or Homsap IGHV3-13*03 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F 76 94.12 16/17 nt 5 X X 5.X.X [0.X.X.X] null + No rearrangement found tggattcaccttcaata 3779 JY8QFUQ01A4B73 unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3780 JY8QFUQ01CK4S1 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3781 JY8QFUQ01AC05Z productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3782 JY8QFUQ01CAAYX No results 3783 JY8QFUQ01CI18Q unknown (see comment) Homsap IGHV3-16*01 ORF 88 53.1 60/113 nt 8 X X 8.X.X [25.4.X.X] null + No rearrangement found ctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3784 JY8QFUQ01DO7RH unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 121 82.86 29/35 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found gtctggatttaccttcagtaagttctggatgcatt 3785 JY8QFUQ01A6FV3 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 418 87.85 94/107 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcatacattagtaggagtagtactgacatatact 3786 JY8QFUQ01AOKPD No results 3787 JY8QFUQ01CWHMD No results 3788 JY8QFUQ01BS7EV No results 3789 JY8QFUQ01A2RKH unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 286 60.1 122/203 nt 10 9 X 10.9.X [2.17.29.X] null - No rearrangement found Low V-REGION identity (60,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release acctccggggacggtgtctctaccaacagtgctgcttggagttcgatcaggcagcccccatcgagaggccttgagtggctgggaaggacatactccgggtccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3790 JY8QFUQ01BSHEV unproductive Homsap IGHV3-9*01 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CSKRHGRGSGTLVT#FDHW out-of-frame + in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cctctggattcGacctttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtagtaaaagacatggtcgcgggtcagggactcttgtcacggttttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 3791 JY8QFUQ01DHJ01 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3792 JY8QFUQ01CJT9B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDAVGLTRLFGDW in-frame + ctctggatttgtctttagtagatatgccatggcctgggtccgccaggctccagggcaggggctggagtgggtcgccagtattggcgggagtggtgataacacatactacgcggactccgtgaagggccggttcaccatctccagagacaactccaataacaaactgtttctgcaaatggacagtttgcgagccggggacacggccagatatttctgtgcgaaagatgcggtgggacttacccgactctttggtgactggggccagggaaccgtggtcagcgccgcctctgcatccccgacagccccaaaggtcttcccgctgagcctcgacagcacccccctcaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3793 JY8QFUQ01DL9F7 unproductive Homsap IGHV1-18*01 F 1001 97.17 206/212 nt 95.28 202/212 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [0.16.37.11] CARDWYPNLEMATTLPFDY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) tggttacacctttaTcgaactatggtatcagctgggtgcgacaggcCccctggacaagggcttgagtggatgggtggatcagcgcttacaatcataacacaactatgcacagaagctccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggaactgaggagcctgagatctgacgacacggccgtgtattattgtgcgagagattggtatcctaacctagagatggctacaaccctcccttttgactactggggccacgggaaccctggtcaccgtctcctctgcctccaccaagggccccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactccag 3794 JY8QFUQ01DEPU9 No results 3795 JY8QFUQ01AKUEW No results 3796 JY8QFUQ01AP6ET unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F (see comment) 583 74.65 159/213 nt 74.18 158/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 7 7 X 7.7.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (74,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctttggtgtctccatctattgttctactgaagatggatccggcagcccccagaattgggactggagtggattggggatctctcttacagtgggaacaccaattacgacccctccctcaagagtcgagtcaccagatcaatagacacgtccaggaaacagttctccccgaacctcacactggggccagggaaccctgggcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3797 JY8QFUQ01ARD7M unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons ctctgaattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3798 JY8QFUQ01AW5U8 productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3799 JY8QFUQ01CF63C No results 3800 JY8QFUQ01DDWWQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 179 60.48 75/124 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found stop codons ctctggattcaacttcaattattatagcatgagttgggtccgccaggctccgggaaagggactggagtgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3801 JY8QFUQ01CWJS5 productive Homsap IGHV3-7*03 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3802 JY8QFUQ01BRSE6 productive Homsap IGHV3-9*01 F 820 86.3 189/219 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [2.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame - gcctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3803 JY8QFUQ01AO2QK No results 3804 JY8QFUQ01A13MR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactaggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3805 JY8QFUQ01AT9NZ unproductive Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CVRGRDGVNFGEMDY## out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactgggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3806 JY8QFUQ01DBU2R productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 89.72 192/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3807 JY8QFUQ01CC515 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 778 84.72 183/216 nt 84.26 182/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-8*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAGETSSTFYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); tggaaaacacctttcgtcaactaccttatacactgggtgcgacaggcccctggtcaagggcCttgaatggatggggtgtatcaaccctagtgacccttacacaaactacgcacagaagttccagggcagactcaccatgaccggggacacgtccacgaacacagtctacatggagctgagcagcctgagatctgaggatgcggccgtgtattactgtgctggagagacatcctctacattctactttgagtcctggggccagggaaccttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtgatcgtcgcatgcctggtccagggcttcttccccca 3808 JY8QFUQ01C4A6Q No results 3809 JY8QFUQ01DA6FV No results 3810 JY8QFUQ01CF194 No results 3811 JY8QFUQ01C0VVG unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 262 62.2 102/164 nt 8 10 X 8.10.X [1.17.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01C0VVG ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3812 JY8QFUQ01CABKE No results 3813 JY8QFUQ01AX2TW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3814 JY8QFUQ01A2SRW productive Homsap IGHV3-13*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - agcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3815 JY8QFUQ01B7SLG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame - ctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3816 JY8QFUQ01BKOGA unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3817 JY8QFUQ01CMDGF No results 3818 JY8QFUQ01AZB12 No results 3819 JY8QFUQ01DPR9B No results 3820 JY8QFUQ01A7Y0G No results 3821 JY8QFUQ01CK8G7 No results 3822 JY8QFUQ01DV1ZT No results 3823 JY8QFUQ01B6HOD productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattgatttatcccggcgggagcacattccacgcagactccgtgaggggcgcctcatcatctccagagacgagtccaagggtgaggtgtatcttcggatgacgagggtgaaaaccgaagacgcggccgtgtattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtctctgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 3824 JY8QFUQ01BG5LR productive (see comment) Homsap IGHV3-7*03 F 819 86.64 188/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); ctccggattcacattcagtaattattggatgagctggatccgccagactccagggaggggcgtggagtAgggtggccaacataaagtacgatggaggtgaagaatactttgcggactctgtgaggggccgagccaccatctccagggacaacaccaaaaaTttctctttatctgcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtccgtcgcatgcctggtc 3825 JY8QFUQ01BQ8KG No results 3826 JY8QFUQ01ALPIB No results 3827 JY8QFUQ01BL7OE No results 3828 JY8QFUQ01C6BX0 productive Homsap IGHV3-66*02 F 876 90.19 193/214 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-16*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAALHDPPWGWLDPW in-frame + ctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3829 JY8QFUQ01CR7CX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3830 JY8QFUQ01ATWJQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEEVWYGSGRGGPK#DYW out-of-frame + in CDR2-IMGT at codon 59 of V-REGION: 'GGA' (3 nucleotides at position 89 to 91 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttaggagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtGGAaatgttgatagcacagactacgcagattccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaaagaagaagtgtggtatggttcggggagaggggggcccaaaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3831 JY8QFUQ01AUMS2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactGgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3832 JY8QFUQ01CQOIV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDKAGFTLHAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttgccagccacgccatggcttgggtccgccggactccaaggaagggcctggagtgggtctcaggcataagtagtagtggtggaaccacgtattacgcagacttcgtgaagggccgcgccactgtctccagagacaattccgagaacacagtgtctctggaactccacagcctgagagccgatgacacggccatatattattgtgtgaaggacaaagcgggcttcaccctccatgcttttgatgtctggggccgagggacggtggtcactgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3833 JY8QFUQ01DDBEG No results 3834 JY8QFUQ01B5HXY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame + gtctggattcacgtttagaaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3835 JY8QFUQ01DGQGM productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 121 66.13 41/62 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGFNFGEMQYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaccataaaccaagacggaagtcggagacactttgtggactctgtggagggccgattcagcatctccagagacagcgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgtgaggggtagagatggcttcaacttcggcgaaatgcagtactggggccagggagccccggtcagcgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3836 JY8QFUQ01CS7JW productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 78 of V-REGION: 'AG' (2 nucleotides at position 135 to 136 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcgaAGtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3837 JY8QFUQ01DTUHV No results 3838 JY8QFUQ01B1E0J No results 3839 JY8QFUQ01CED09 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 3840 JY8QFUQ01B4NF6 unproductive (see comment) Homsap IGHV3-7*01 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.16.38.11] CATSPYGDYWEGR#YW out-of-frame - stop codons in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) cctctagatcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3841 JY8QFUQ01CH02B productive Homsap IGHV3-11*01 F 828 87.1 189/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame + ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3842 JY8QFUQ01A0D2K productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3843 JY8QFUQ01CUE1Y productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + ttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3844 JY8QFUQ01C559L unproductive (see comment) Homsap IGHV3-7*01 F (see comment) 423 65.9 143/217 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.17.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,90% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3845 JY8QFUQ01ANMGM No results 3846 JY8QFUQ01B6WTL No results 3847 JY8QFUQ01CBJ3P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3848 JY8QFUQ01A444V No results 3849 JY8QFUQ01B1G48 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3850 JY8QFUQ01BZZFO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctggaccagccccaaggctcttccgctgagcctccgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3851 JY8QFUQ01DNBP1 No results 3852 JY8QFUQ01BP2VQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) cctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3853 JY8QFUQ01BXOZU unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 3854 JY8QFUQ01CVHT1 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 104 52.94 72/136 nt 8 8 X 8.8.X [2.17.10.X] null - No rearrangement found stop codons gcctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3855 JY8QFUQ01B7NMF No results 3856 JY8QFUQ01BC4J6 No results 3857 JY8QFUQ01BLZAU No results 3858 JY8QFUQ01C1T5U No results 3859 JY8QFUQ01BJ353 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.16.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaagggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3860 JY8QFUQ01A1V7G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDLALGGGSCWHYW in-frame + ctctggattcacctttagcagatatgccatgacctgggtccgccaggctccagggaagggactggagtgtgtctcagctattagtggtgatggcgctaacacattctacccaagttccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatctgcagatggacagcctgagagccgaagacacggccgtatattactgtgcgaaagatctggcgttgggtggtggtagctgctggcactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca 3861 JY8QFUQ01DHBP6 unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3862 JY8QFUQ01ADM37 No results 3863 JY8QFUQ01CNW28 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3864 JY8QFUQ01AQ8FC productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3865 JY8QFUQ01BSGAY productive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 104 of V-REGION: 'C' (1 nucleotides at position 220 to 220 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttCgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact 3866 JY8QFUQ01CO2BZ No results 3867 JY8QFUQ01BIC0A unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 178 55.68 98/176 nt 8 7 X 8.7.X [1.17.25.X] null + No rearrangement found ctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3868 JY8QFUQ01A0V1E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 3869 JY8QFUQ01C8AF9 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 134 55.64 74/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagccacccccgaagatgggaacgtgtcgtcgcatgcctggtccagggcttcttccccc 3870 JY8QFUQ01B5NZK unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 943 93.9 200/213 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGVGQQLPP*#W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctagtggctccatcaatgcttactactggagctggatccggcagtccccggggaagggactggagtggatgggatatatctatgacagtgggagcaccaactacaacccctccttcaagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtttattactgtgcgagaggggtggggcagcaactgcccccttagagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 3871 JY8QFUQ01C7KW5 No results 3872 JY8QFUQ01BCTSU No results 3873 JY8QFUQ01AVO0G productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 845 90.29 186/206 nt 89.81 185/206 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtttataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3874 JY8QFUQ01CPKQV unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 80 51.13 68/133 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3875 JY8QFUQ01APVVP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3876 JY8QFUQ01BHWUR No results 3877 JY8QFUQ01DW734 No results 3878 JY8QFUQ01B8OTM No results 3879 JY8QFUQ01C9T80 No results 3880 JY8QFUQ01AOUC3 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 746 83.26 179/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3881 JY8QFUQ01ADQHC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3882 JY8QFUQ01CFBFI productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccgtcagcagtgataactggtggaGgttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3883 JY8QFUQ01DGVL6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3884 JY8QFUQ01CO7LQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 3885 JY8QFUQ01DELV5 productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3886 JY8QFUQ01AJ9A6 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 756 83.41 181/217 nt 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) cgtctggattcagttcagtaccctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggactcaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatttgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3887 JY8QFUQ01AMH2G No results 3888 JY8QFUQ01A3RHO No results 3889 JY8QFUQ01BEVNG unknown (see comment) Homsap IGHV5-51*05 F 156 52.94 108/204 nt 8 8 X 8.8.X [X.17.38.X] null + No rearrangement found stop codons ggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3890 JY8QFUQ01ABTRX No results 3891 JY8QFUQ01A8ALV productive Homsap IGHV3-48*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + tctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3892 JY8QFUQ01ATUS3 No results 3893 JY8QFUQ01BIDT5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 796 85.65 185/216 nt 84.72 183/216 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctctgggattcagcttaagttcttatggcatgaactggtccgccagcgtccatgggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3894 JY8QFUQ01DEI6W No results 3895 JY8QFUQ01BJ183 No results 3896 JY8QFUQ01B63PV productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD5-12*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDQRDYDYIYYYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 152 to 152 in the user submitted sequence), (cause frameshift); ctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtattatgcagacttcgtgaagggccgattcaccatcaccagggacaatTtcccagaacactctgtctctgcaattgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacgggatggacctctggggccaaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttccgctgagcctctgcgcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3897 JY8QFUQ01AFS6I unproductive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPRSVSRYSLFDSW# out-of-frame - stop codons in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaaataGagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatTttttgtgcgagagatcctcgttccgtgagcaggtactctttatttgactcctgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3898 JY8QFUQ01B2UFO productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagccCcgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3899 JY8QFUQ01ATJND No results 3900 JY8QFUQ01BNYIU productive (see comment) Homsap IGHV4-61*02 F 897 90.0 198/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3901 JY8QFUQ01ATMYD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 3902 JY8QFUQ01AX0UJ No results 3903 JY8QFUQ01DVMEJ No results 3904 JY8QFUQ01A9KHI productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARWGATWELLLGNLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggAcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacGaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagatggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3905 JY8QFUQ01BR91W No results 3906 JY8QFUQ01AT5T6 No results 3907 JY8QFUQ01CNIKN unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F (see comment) 327 64.97 115/177 nt 64.41 114/177 nt 7 8 X 7.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (64,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcaccttcactagaagtccatgaattgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgcagcacccagccagatgggaacgtggtcatcacctgcctggtccagggcttcttccccca 3908 JY8QFUQ01BZUY8 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ctctggattcagcttcagtacctataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3909 JY8QFUQ01AT14G productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 7 8 15 7.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ttctggattcagtcctaccgattttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccatccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 3910 JY8QFUQ01DTNQN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CANELGYCSGA## out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgcgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3911 JY8QFUQ01C9728 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3912 JY8QFUQ01A5RXF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); ccctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccaattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3913 JY8QFUQ01A24L7 productive Homsap IGHV1-24*01 F (see comment) 279 66.91 91/136 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 2 X 7 8 X.7.8 [X.X.38.11] CARRSVLDIW in-frame + Low V-REGION identity (66,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacgcgttcagaaatcatgacattaactggaagtttcagggcagagccaccatgaccagggatacgtccacagatacagcctatttagaagtgaacggcctgggacctgaggacacggccgtgtattactgcgcgaggcggagtgttcttgatatctggggccaaggaacaagggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3914 JY8QFUQ01C0P9U productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3915 JY8QFUQ01B1GX5 unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.17.38.11] CARGAPFS**C in-frame + stop codons ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3916 JY8QFUQ01BLTOE No results 3917 JY8QFUQ01A4IGN productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 3918 JY8QFUQ01C15AT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.37.11] CANEVGYCSGG# out-of-frame - in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 3919 JY8QFUQ01DKID1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3920 JY8QFUQ01DFWGJ unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga 3921 JY8QFUQ01BSY1C productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3922 JY8QFUQ01A4005 No results 3923 JY8QFUQ01BVLE3 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggaacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3924 JY8QFUQ01CC9XC productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ6*01 F 252 88.89 56/63 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRYWGSYYYYNGLDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatattggggcagctactattactataacggtctggacgtctgggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3925 JY8QFUQ01DF6AO No results 3926 JY8QFUQ01DVYEJ No results 3927 JY8QFUQ01BHN92 No results 3928 JY8QFUQ01CHC60 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1022 94.71 215/227 nt 94.27 214/227 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 9 9 14 9.9.14 [2.17.38.11] CARGGNYYDSGGLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) atctccggggacagtgtctctagcagcagtgttgttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3929 JY8QFUQ01DJCKC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDLGLVGATGLDYW in-frame + ctctggattcacctttcgcagatatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattaataatagtggtggtagcacatactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcaactgagcagcctgagagccgaggacacggccatgtatttctgtgtgaaagatctgggactagtgggcgctactgggctggactactggggccagggaacccgggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccggctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3930 JY8QFUQ01AFD8Y No results 3931 JY8QFUQ01AT4CD No results 3932 JY8QFUQ01C7LJW productive (see comment) Homsap IGHV4-4*07 F 782 85.12 183/215 nt 83.72 180/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 8 7 18 8.7.18 [1.17.38.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CAGTGG' (6 nucleotides at position 20 to 25 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggaggctccatcagCAGTGGaagttactactggacctggatccggcagcccgccgggaagactctggagtggatTtgggcgcttctacagtcgtCgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggctgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3933 JY8QFUQ01CQWKF productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 7 8 13 7.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) tctggattcaactcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3934 JY8QFUQ01BRC8T No results 3935 JY8QFUQ01CMMDZ No results 3936 JY8QFUQ01B2SZG unproductive (see comment) Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3937 JY8QFUQ01BUJLR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAREGGRGYDMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 3938 JY8QFUQ01DPX3I No results 3939 JY8QFUQ01B3ZD4 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccaggggaaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3940 JY8QFUQ01DW3GZ No results 3941 JY8QFUQ01DEEDN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + ctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 3942 JY8QFUQ01AW2Y4 productive Homsap IGHV3-11*01 F 1044 98.16 213/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARVVGATLYYFDYW in-frame + ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtgttagtgccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgcccagaactcactgtatctgcaaatgcacagcctgagagccgaggacacggccgtgtattactgtgcgagagtagtgggagctaccctgtactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3943 JY8QFUQ01B2VIG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 924 91.36 201/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARSYGFSRFDPW in-frame + ctctggtggctccatcaccagtagtctttaccgctggggctggatccgccagtccccagggaagggcctggagtggatagggaatatcttttatggtgggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3944 JY8QFUQ01BOS92 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAREASNGNYNLVFDYW in-frame + gtctggattcaccttcagtgaccatgccatgcactgggtccgccaggctccaggcaaggggctggagtcggtggcagttatatggtatgatggaagtaataaactttatgcggactccgtgaagggccgcttcaccatctccagagacaattccaagaacatgctgtatctgcagatgagcagcctgagagccgaagacacggctgtgtatttctgtgcgagagaagcctctaatgggaactacaacctcgtctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3945 JY8QFUQ01CUM4N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + ctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3946 JY8QFUQ01B74LF unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3947 JY8QFUQ01CQ64D No results 3948 JY8QFUQ01CAGK7 No results 3949 JY8QFUQ01A5U3W productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgagaacgtggtcatcgcctgcctggtccagggcttcttccccca 3950 JY8QFUQ01AGNL8 productive (see comment) Homsap IGHV3-7*03 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [0.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctggattcaccttcaggagctattggatgagctgggtccgccaggctccagGggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3951 JY8QFUQ01C9A0A productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 3952 JY8QFUQ01CU1O9 No results 3953 JY8QFUQ01BCYGH No results 3954 JY8QFUQ01BW5IP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 859 95.24 180/189 nt 94.18 178/189 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.7.37.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 28 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 108 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagaatgaactggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcacatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 3955 JY8QFUQ01BZ3ER unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 95 100.0 19/19 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found tctggattcacctttagta 3956 JY8QFUQ01BX34R productive Homsap IGHV3-9*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDKGGSNWKYFDLW in-frame + ctttggattcaagtttgatgattatgccatgcactgggtccgacaagttccagggaagggcctggagtgggtctcaagtataagttggggtagtaggaccatagtctatgcggactctgtgaaggaccgattcaccgtctccagagacaacatcaggaagtccctctatctgcaaatggacagcctgagacctgacgacacggccctctattactgtgcaaaagacaagggcggcagcaactggaaatactttgacctctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3957 JY8QFUQ01CJSXO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVAVGMSGWFDPW in-frame + ctctggattcaccttcagtgggtcttggatgcactgggtccgccaagctccagggaaggggctggtgtgggtttcacgtattaatcgtgatggcagtagcacaagctacggggactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttgggatgtcaggctggttcgacccttggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3958 JY8QFUQ01DDNJZ No results 3959 JY8QFUQ01A1BIU No results 3960 JY8QFUQ01A5ZKW productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 930 91.03 203/223 nt 90.58 202/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTRPRGWEPLGLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatggtctgggtccgccaggctccagggaaggggctggagtgggttggccttattaagaccaaacctgatggttggacaacaatctactctgcacccgtgAaaaggcagattcatcatttcaagagatgattcaaaaaacatggtgtttctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtaccacacggccccgggggtgggaaccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaaggtcttccccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3961 JY8QFUQ01DEIMF No results 3962 JY8QFUQ01DE72N productive Homsap IGHV4-34*06 F (see comment) 701 80.84 173/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 14 8.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tccatggtgggtccctcaggggttacccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 3963 JY8QFUQ01DI5ZW unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.35 205/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.16.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3964 JY8QFUQ01CEUVW No results 3965 JY8QFUQ01BS8OE productive (see comment) Homsap IGHV3-11*01 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGKMVSTGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); gctctggattcacgtttagtgactactacatgacctggattcgtcaggctccagggaagggcctggagtgggttacatatattagtagtagtggtggtaacacacattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgaggGgccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3966 JY8QFUQ01CLT9N No results 3967 JY8QFUQ01AJ6YX No results 3968 JY8QFUQ01C8XBU No results 3969 JY8QFUQ01AEKWU productive Homsap IGHV3-48*02 F (see comment) 719 81.4 175/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [0.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3970 JY8QFUQ01AJCMG productive (see comment) Homsap IGHV3-11*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 95 to 97 in the user submitted sequence), (do not cause frameshift); ttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag 3971 JY8QFUQ01BR4UW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 231 57.81 111/192 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (57,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 3972 JY8QFUQ01C77T7 No results 3973 JY8QFUQ01A21B3 No results 3974 JY8QFUQ01DURUL productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-NL1*01 F 844 88.73 189/213 nt 88.26 188/213 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 3975 JY8QFUQ01CIVDS No results 3976 JY8QFUQ01B933L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3977 JY8QFUQ01DSZ8R No results 3978 JY8QFUQ01BHZCF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 3979 JY8QFUQ01C4JWB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.37.11] CARRTITAAGRGDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 132 in the user submitted sequence), (cause frameshift) cctctgaattcacctttagcagAttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggtcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3980 JY8QFUQ01BNKOY No results 3981 JY8QFUQ01AS6KG No results 3982 JY8QFUQ01AMWVF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 3983 JY8QFUQ01B0OXJ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3984 JY8QFUQ01DENNK No results 3985 JY8QFUQ01A5C0K No results 3986 JY8QFUQ01CCIHD No results 3987 JY8QFUQ01BOCYN No results 3988 JY8QFUQ01DMKY7 No results 3989 JY8QFUQ01BZ1D4 productive Homsap IGHV3-7*03 F 832 87.5 189/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3990 JY8QFUQ01CGNEG unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 3991 JY8QFUQ01AL3H2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDRMIHTMRG#FDMW out-of-frame - cctctggattcaccttcagaaccaatgccatgaactgggtccgccaggctccagggaaggggctggagtggatctcagttattaatggtcccggtgatatcacatactacgcagactccgtgaagggccggttcaccatgtcccgagacaattccaaggacacgttgtatttgcaaatgatcagcctgagaggcgaggacacggccatatattactgtgcaaaagatcgtatgatacacacgatgaggggagctttgatatgtggggccgagggacaatggtcaccgtctcttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 3992 JY8QFUQ01A0GSS No results 3993 JY8QFUQ01B6AJY No results 3994 JY8QFUQ01BPA4Z No results 3995 JY8QFUQ01AIKEQ No results 3996 JY8QFUQ01DB2BI No results 3997 JY8QFUQ01CYCIU No results 3998 JY8QFUQ01AROLJ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 89 51.88 69/133 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 3999 JY8QFUQ01C35HE No results 4000 JY8QFUQ01DMY5F unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4001 JY8QFUQ01AZQGR unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 3 8 10 X 8.10.X [1.17.38.11] CVVDIPEVGVGA#FDYW out-of-frame + stop codons ctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttggtgtgggggcaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgatcatcgcctgcctggtccagggcttcttccccca 4002 JY8QFUQ01DRHQR No results 4003 JY8QFUQ01C10GW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 442 93.07 94/101 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 4004 JY8QFUQ01AYXGF No results 4005 JY8QFUQ01BGU6I unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 474 82.61 114/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 4006 JY8QFUQ01BZPQW No results 4007 JY8QFUQ01BLGYX productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-1*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARRQLALAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); tggatacacctttatcacctactggatcgcctgggtgcgccaaatgcccgggaaAaggcctggagttgatgggagtcatctatcctggtgactctgagaccagatacagcccgtCccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4008 JY8QFUQ01B3Q8U No results 4009 JY8QFUQ01BNVNO productive (see comment) Homsap IGHV3-74*03 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 7 14 8.7.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4010 JY8QFUQ01BMI6W productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggGcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4011 JY8QFUQ01C4WW4 productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4012 JY8QFUQ01AV66V No results 4013 JY8QFUQ01ADD8V productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4014 JY8QFUQ01DC351 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 468 68.2 148/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4015 JY8QFUQ01B30JH No results 4016 JY8QFUQ01C0RZ5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + ctctggattcactttcagtagctactggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4017 JY8QFUQ01DQS4M No results 4018 JY8QFUQ01AF1GF No results 4019 JY8QFUQ01CCM2W No results 4020 JY8QFUQ01AP8KN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [0.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4021 JY8QFUQ01DUEJN productive Homsap IGHV3-33*04 F (see comment) 688 80.09 173/216 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release attggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4022 JY8QFUQ01B4TSY unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 918 91.71 199/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARRDVGLHAFDL## out-of-frame + ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggcccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4023 JY8QFUQ01AHN2J No results 4024 JY8QFUQ01A6E0M productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgAaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4025 JY8QFUQ01BUEWQ No results 4026 JY8QFUQ01A80I1 unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 1083 98.65 220/223 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 10 X 8.10.X [1.17.38.11] CTPWWRGGYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ttctggattcacctctggtgattatgctatgagctggctccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaaccatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccccgtggtggcggggaggttactttgactactgggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 4027 JY8QFUQ01CAW1S productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4028 JY8QFUQ01CST6S productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4029 JY8QFUQ01DAV14 unknown (see comment) Homsap IGHV3-48*03 F 873 89.4 194/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4030 JY8QFUQ01COVOC No results 4031 JY8QFUQ01A1LZR No results 4032 JY8QFUQ01BIUX6 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat 4033 JY8QFUQ01C238V productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4034 JY8QFUQ01C9757 productive Homsap IGHV4-61*02 F (see comment) 735 81.82 180/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 16 10.7.16 [1.17.38.11] CARERFRSTGGARDFDSW in-frame + Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcagcagtggtgatcacttctggagctggatccggcagcccgccgggaagggactggagtggattggacatgttcactatggtggggtcaccaattacaatccttccctccagggtcgggtcatggtgtctatggacacgtccaagagccagttcttcctgacgatgacctccgtgaccgccgcagacacggccacatattactgtgcgagagagcgtttcaggtcgacgggcggagcgagagattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 4035 JY8QFUQ01A1FEA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CGKQLGPIKG#DYW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattggggcccataaaggggctgactactggggccaggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 4036 JY8QFUQ01AVG7B unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHRSFWSDNC##YFESW out-of-frame + stop codons Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactgGgggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtctttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 4037 JY8QFUQ01AGRO9 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 55 100.0 11/11 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found ctctggattca 4038 JY8QFUQ01CLT7T No results 4039 JY8QFUQ01DS2A4 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 428 77.24 112/145 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found Low V-REGION identity (77,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttcccc 4040 JY8QFUQ01BBL67 No results 4041 JY8QFUQ01CQ084 No results 4042 JY8QFUQ01BG6U2 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca 4043 JY8QFUQ01AQYW8 unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 924 91.36 201/220 nt 90.91 200/220 nt 10 7 X 10.7.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagccccagggaagggactggagtggattggtcatttctatcacattgggagcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagagcatccccgaccagccccaaggctcttcccgctgagcctctgcagcacccagccacgatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 4044 JY8QFUQ01CUEVN productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4045 JY8QFUQ01DCCBW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4046 JY8QFUQ01BJV9I productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtaCtaaaaagctacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 4047 JY8QFUQ01A5J2Z No results 4048 JY8QFUQ01DT092 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4049 JY8QFUQ01ATQQA No results 4050 JY8QFUQ01A50E7 No results 4051 JY8QFUQ01CH3O2 No results 4052 JY8QFUQ01CY3N7 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 964 93.61 205/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [2.17.38.11] CAREGEIR*RRRG#WFDPW out-of-frame - stop codons gcgtctggattcaccttcagtgactctggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatggtatgatggatattataaacaacatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattactgtgcgagagaaggtgaaatacggtgacgacgacggggggtggttcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4053 JY8QFUQ01CREG4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4054 JY8QFUQ01AJSWL No results 4055 JY8QFUQ01DMRZW productive (see comment) Homsap IGHV4-39*03 F 902 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [2.16.38.11] CTREGPYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) tgctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4056 JY8QFUQ01BM7RX No results 4057 JY8QFUQ01AG74C productive Homsap IGHV1-8*01 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame + tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4058 JY8QFUQ01DHMPB No results 4059 JY8QFUQ01DEL0X unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSEFLLDG#YW out-of-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgagtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4060 JY8QFUQ01DNF0K productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4061 JY8QFUQ01B6ARD No results 4062 JY8QFUQ01CRH4Y No results 4063 JY8QFUQ01CU6OD No results 4064 JY8QFUQ01CDU8X No results 4065 JY8QFUQ01C7NRF productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 4066 JY8QFUQ01CKFJO No results 4067 JY8QFUQ01DP9WU No results 4068 JY8QFUQ01BL0WJ No results 4069 JY8QFUQ01DTMAK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 401 89.0 89/100 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca 4070 JY8QFUQ01DD7YS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4071 JY8QFUQ01DLWK8 productive (see comment) Homsap IGHV1-8*01 F 835 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.37.11] CARVGGTHYHYGVDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 189 in the user submitted sequence), (cause frameshift) cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagattgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4072 JY8QFUQ01AZDAE unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 440 76.82 116/151 nt 8 7 X 8.7.X [2.17.16.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AZDAE ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag 4073 JY8QFUQ01BCLHY productive (see comment) Homsap IGHV1-24*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4074 JY8QFUQ01BDD2F No results 4075 JY8QFUQ01CDTDW No results 4076 JY8QFUQ01A1E4A No results 4077 JY8QFUQ01DHS0J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcacctttagaagctatgccatgagctggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4078 JY8QFUQ01ANPYU unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4079 JY8QFUQ01BRMTT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 800 86.05 185/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] FARDSSNWSDAFDIW in-frame - Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactttgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4080 JY8QFUQ01DRNVI productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4081 JY8QFUQ01BB4R2 unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatgGgaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4082 JY8QFUQ01B95P9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4083 JY8QFUQ01BKUF9 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - agcctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4084 JY8QFUQ01AECJJ No results 4085 JY8QFUQ01A6UXG No results 4086 JY8QFUQ01C39VS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 789 84.55 186/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [2.17.38.11] CARRSGRDG#WFDSW out-of-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) aatctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4087 JY8QFUQ01AM7GA No results 4088 JY8QFUQ01BH8UX unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.35 205/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.16.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataatttacggtgactactgggggcccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4089 JY8QFUQ01DE15S No results 4090 JY8QFUQ01BT9VW productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 4091 JY8QFUQ01B44L7 No results 4092 JY8QFUQ01AYT06 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 245 58.55 113/193 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (58,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4093 JY8QFUQ01AYQNM unknown (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4094 JY8QFUQ01C0ALR productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 868 89.35 193/216 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [2.17.38.11] CASGGYSGSGEYFLRW in-frame - gcctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4095 JY8QFUQ01ACUIR No results 4096 JY8QFUQ01DWE3X productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 4097 JY8QFUQ01A5EAU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARDLYGTDDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtaccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 4098 JY8QFUQ01DFR67 No results 4099 JY8QFUQ01DGFY7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4100 JY8QFUQ01C8KXH No results 4101 JY8QFUQ01A2VEW unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F 121 50.97 105/206 nt 8 8 X 8.8.X [1.17.34.X] null + No rearrangement found ctctggattcaactttgaagattatgccatgtactgggtccgacaacctccagggaagggcctggagtgggtctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4102 JY8QFUQ01BOMRH No results 4103 JY8QFUQ01BSU32 No results 4104 JY8QFUQ01AX4Q2 unproductive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARYDFLEWLFLRG#YYFDYW out-of-frame + cctctggattcacctttagtgactattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcagatgaacagcctgagagtcgaggacacggctatgtattactgtgcgaggtacgattttttggagtggttattcctccggggcactactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccc 4105 JY8QFUQ01BUW2X unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 134 68.85 42/61 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found cctctggattcacctttagtaaccattggatgaactgggtccagggcttcttcccccagga 4106 JY8QFUQ01CU30H productive (see comment) Homsap IGHV3-9*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.37.11] CAKATTAWYSGGLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) ctctggattcaactttgatgattacggcatgcactgggtccggcaacgcccagggatgggcctggagtgggtcgcaggtattagttataataatggccacaaagaatatgcggactctgtgagggccgattcaccatctctagagacaacgccaggaagtccctgtatctgcagatggacagtctgagagttgaggacacggccttgtattattgtgcaaaggctacaactgcctggtattcaggcggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4107 JY8QFUQ01BRYZC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4108 JY8QFUQ01CYMFP No results 4109 JY8QFUQ01A5V13 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1056 98.61 213/216 nt 97.69 211/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccGttcagtagctatagcatgaactgggtccgccagntccagggaacgggctggantgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4110 JY8QFUQ01CDGEE No results 4111 JY8QFUQ01CVP6Z No results 4112 JY8QFUQ01BRVEF No results 4113 JY8QFUQ01C1EOS unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4114 JY8QFUQ01CUZCV No results 4115 JY8QFUQ01C70SB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 4116 JY8QFUQ01BTJ0N productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4117 JY8QFUQ01C88JT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4118 JY8QFUQ01C26RF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 720 81.11 176/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [1.17.38.11] CAKGGHDLGSYYYGLDVW in-frame + Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaattctccatgtattggatccgccaggctccaggggaggggctggagtggatctcaggtatgaggggacaagattcggccacacactatgcagactccgtgaagggccagttcaccatctcgagagacaacgccaagaacacactgtatctgcagatgaacagtctcagacccgatgacacggccatttattattgcgcgaaaggaggtcatgaccttggcagttactactacggtctggacgtttggggccaagggactacggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4119 JY8QFUQ01CS08M unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CASGGYSGSGEYFLR## out-of-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctgggggccagggcaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4120 JY8QFUQ01DGRQC No results 4121 JY8QFUQ01C1R8S No results 4122 JY8QFUQ01AQTR0 unproductive (see comment) Homsap IGHV3-9*01 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CSKRHGRGSGTLVT#FDHW out-of-frame + stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); ctctggattcGacctttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtagtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4123 JY8QFUQ01CWANU unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGAGAEGKGGMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggcccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4124 JY8QFUQ01DHKDQ No results 4125 JY8QFUQ01CRD7R productive Homsap IGHV3-9*01 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-11*01 ORF 2 8 8 21 8.8.21 [1.17.38.11] CAKDLFRWNDYSDSNNYYAMGVW in-frame + ctctggattcagttttgaccattttgccttccactgggtccgactagctccagggaagggcctggagtgggtctcaggcattagttgggatagttctgatgtagtctatgcggactctgtgaggggccgcttcatcatctccagagacaacgtcaagaagtccctgtatctggacatgaacagtctgagagttgaggacacggccttgtactactgtgcaaaagatctttttaggtggaacgactatagtgactcgaataactactatgcaatgggcgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4126 JY8QFUQ01DT8AO productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 813 86.92 186/214 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVGVGVGSSVSFQYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactgtcaataacaactacatgggttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacactttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4127 JY8QFUQ01APAFI productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatCccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4128 JY8QFUQ01CDAWJ productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 4129 JY8QFUQ01CQ9EF unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 845 87.91 189/215 nt 87.44 188/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4130 JY8QFUQ01AO78J unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 4131 JY8QFUQ01ANQ9X No results 4132 JY8QFUQ01C4DFU No results 4133 JY8QFUQ01CT3S3 No results 4134 JY8QFUQ01AHPZ4 unproductive (see comment) Homsap IGHV3-11*06 F, or Homsap IGHV3-48*04 F 781 85.45 182/213 nt 83.57 178/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CAKR*#YGDYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcgggaaCctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaacgccaagaacAcctctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcgaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 4135 JY8QFUQ01BSRK2 No results 4136 JY8QFUQ01BBQG8 productive Homsap IGHV4-4*07 F 953 93.95 202/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt 8 7 9 8.7.9 [1.17.38.11] CARGDWYFDLW in-frame + tctctggtggctccatcattaatcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtagtcataccagtggaagcaccaggtacaacccctccctcaagagtcgagtcaccgtgtcagcagacacgtccaagaaccagttctccctgaagcttagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggagactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4137 JY8QFUQ01AH6V1 No results 4138 JY8QFUQ01BYX7U No results 4139 JY8QFUQ01DDMNP productive Homsap IGHV3-7*01 F 857 89.15 189/212 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 7 8 10 7.8.10 [X.17.38.11] CVVSSGWLFHYW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4140 JY8QFUQ01A528Y productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - ctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4141 JY8QFUQ01CZGPL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4142 JY8QFUQ01C3CBO productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 7 8 10 7.8.10 [0.17.38.11] CASFRVLESGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) tggattcacattcggagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4143 JY8QFUQ01CXP6H unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4144 JY8QFUQ01BBTVQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 865 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ggcctcctggattcacCctttggttattatggcatgactggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4145 JY8QFUQ01DTK6X No results 4146 JY8QFUQ01AZ8WQ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggaAgcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggaccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc 4147 JY8QFUQ01DH217 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1036 97.26 213/219 nt 96.8 212/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.16.38.11] CARLDYTRYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagcagtagtagttactactggggctggatccgccagccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4148 JY8QFUQ01B5YSY unknown (see comment) Homsap IGHV4-59*02 F 894 90.65 194/214 nt 89.72 192/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 20 to 22 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 107 to 118 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4149 JY8QFUQ01A216B unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 405 77.78 105/135 nt 76.3 103/135 nt 7 6 X 7.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4150 JY8QFUQ01AJAE8 No results 4151 JY8QFUQ01BULC2 No results 4152 JY8QFUQ01AXRKK No results 4153 JY8QFUQ01DOYU9 No results 4154 JY8QFUQ01BRAIG No results 4155 JY8QFUQ01AJJ06 productive Homsap IGHV3-11*01 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CAGSFCGGGCLWPTYHFENW in-frame + ctctggattcccctttaaggactactccatgaactggatccgccaggctccagggaagggactggagtggatttcatacatgagcagcactggtgagaccatatattacgcggactttgtgaagggccgattcaccatctccagggacaccgccaagaatctgttgtttctgcaaatgaattacctgcgagacgaggacacggccatgtattactgtgcgggatcattttgtggtggtggctgcttgtggcccacatatcactttgaaaactggggccagggagccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4156 JY8QFUQ01AOR7N productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag 4157 JY8QFUQ01C8YU1 No results 4158 JY8QFUQ01DXHVC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 459 68.2 148/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttcccctgcgcctcgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4159 JY8QFUQ01BL8LS unproductive Homsap IGHV3-21*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CATGAGNWNYIFNF## out-of-frame + cctccggcttcgacttcagtagatacaacataaactgggtccgccaggctccagggcagggactggagtgggtctcctctattagttatagtagcacttacatatactacgcagactcggtgaaaggccgcttcaccatctccagggacaacgccaagaactcggcatctctgcaaatgaacaacctgagagccgaggacacagctgtgtattactgtgcgacaggggccggaaactggaactacatttttaacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4160 JY8QFUQ01CHCVV No results 4161 JY8QFUQ01CBF1Z No results 4162 JY8QFUQ01CTSJZ productive Homsap IGHV4-34*03 F 917 92.06 197/214 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 8 7 18 8.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame - tgtatggtgggtccttcagtgataactcctggacctggatccgccagcccccagggaaggggctggagtggattggagagatcaatcatagtggaaacaccaactacaacccgtccctcaggagtcgagtaatcatgtcaatagacacgtccatgaaccaattctccctgaagctgacttctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4163 JY8QFUQ01CKW45 productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4164 JY8QFUQ01DW86D productive Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 4165 JY8QFUQ01ASR1L No results 4166 JY8QFUQ01AI26Z No results 4167 JY8QFUQ01BGUEI unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 60 100.0 12/12 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found cctctggattca 4168 JY8QFUQ01CXFTI No results 4169 JY8QFUQ01COANG No results 4170 JY8QFUQ01C6K15 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 375 89.25 83/93 nt 88.17 82/93 nt 8 6 X 8.6.X [1.15.X.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 4 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggctggagtgggtctcagccattagtggcagtggtagt 4171 JY8QFUQ01BD39R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaatatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 4172 JY8QFUQ01A6LU1 unproductive Homsap IGHV3-7*01 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSAYFSTGY# out-of-frame + tctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaaaggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4173 JY8QFUQ01C0CV0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CAKEGPTLLTRPLS#W out-of-frame + tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaatacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgccccctctcaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4174 JY8QFUQ01BAQF9 No results 4175 JY8QFUQ01CZ6D5 No results 4176 JY8QFUQ01C02GH No results 4177 JY8QFUQ01A6V15 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGQFGTVMDYW in-frame + cctctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggatggggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgttttttattgtgcgaaaggccagtttggtaccgtcatggactattggggccagggaacccaggtcgtcgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg 4178 JY8QFUQ01DM4VX productive Homsap IGHV3-7*03 F 865 88.58 194/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [2.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - gcctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 4179 JY8QFUQ01AA4FG No results 4180 JY8QFUQ01ADRD7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 845 90.29 186/206 nt 89.81 185/206 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactcccacttctggagctggatccggcagcccccgggaaagggcctggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 4181 JY8QFUQ01AIQK6 No results 4182 JY8QFUQ01DDSRJ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4183 JY8QFUQ01BAM3C productive Homsap IGHV3-7*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + tctggattccagtttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 4184 JY8QFUQ01C4VFW productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4185 JY8QFUQ01DJ70M unknown (see comment) Homsap IGHV3-23*05 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4186 JY8QFUQ01BZLBZ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4187 JY8QFUQ01DS8U8 productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4188 JY8QFUQ01DJGQ4 productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaAagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4189 JY8QFUQ01BBNNQ No results 4190 JY8QFUQ01CY764 productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ3*01 F 142 76.0 38/50 nt Homsap IGHD4-17*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4191 JY8QFUQ01DUPRD productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaGcccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4192 JY8QFUQ01CBXSO unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1043 96.43 216/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-11*01 ORF 2 8 10 X 8.10.X [1.17.38.11] CTRGGIQL#AYW out-of-frame + cttctggattcacctttggtgattatgctatgagttggttccgccaggctccagggaaggggctggagtgggtaggtttcattggaggcagagctcatggtggggcaacagaatacgccgcgtctgtgaaaggcagattcatcatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtactagagggggaatacagttatgcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 4193 JY8QFUQ01ABKEP No results 4194 JY8QFUQ01AZK7Y productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 4195 JY8QFUQ01AN73J productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacct 4196 JY8QFUQ01DKQIL productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + tggatacaccttcagcgactactacatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggctgaaccctaataatggtgacacagcttatggccagagctttcagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggcttttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 4197 JY8QFUQ01AHM6C No results 4198 JY8QFUQ01C7M32 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 995 93.39 212/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 X 10.9.X [1.17.38.11] CARGSSRGGILMGSTMN#DYW out-of-frame - tctccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcgggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4199 JY8QFUQ01CRMOX productive (see comment) Homsap IGHV3-9*01 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.16.38.11] CAKDGDSGWDYYDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) ctctggatttaactttgatcaatatgccatgtattggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaaggacccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4200 JY8QFUQ01DWDCF No results 4201 JY8QFUQ01DPSK7 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 468 68.2 148/217 nt 67.28 146/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaGgtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcaTgggtatacctggcagactccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4202 JY8QFUQ01CXSTH unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 576 73.73 160/217 nt 73.27 159/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (73,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggTccgattcaccatctccagagacaattccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4203 JY8QFUQ01AF6KD unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F 481 94.44 102/108 nt 93.52 101/108 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 1 8 X X 8.X.X [1.16.10.11] CAKTTMTSVTTTGS#PL out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 106 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) ctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttaaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctgggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4204 JY8QFUQ01B5FLY productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggccaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4205 JY8QFUQ01ATAE0 No results 4206 JY8QFUQ01BY0E2 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARFSGSYKSAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tctggatacatctttaccgactattggatcggctgggtgcgccagacggccgggaaAaggcctggagtggatggggaAtcatctatcctggtgactctgacaccagttatggcccgtccttccaaggccaggtcaccatttcagccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatcccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccgagg 4207 JY8QFUQ01BDAQ6 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 949 91.56 206/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 7 11 8.7.11 [5.17.38.11] CARFGPLTRPDYW in-frame - gcctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4208 JY8QFUQ01DGVPH No results 4209 JY8QFUQ01AI4VB unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 420 76.19 112/147 nt 8 7 X 8.7.X [1.17.16.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AI4VB ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactca 4210 JY8QFUQ01BH58R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 769 84.26 182/216 nt 82.87 179/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [2.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) cgtctgggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 4211 JY8QFUQ01CHR9J No results 4212 JY8QFUQ01BG0NL unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4213 JY8QFUQ01A5JH6 No results 4214 JY8QFUQ01CNH36 productive Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 863 89.3 192/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4215 JY8QFUQ01CO5QA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggctgggAgacatcaactttaaaggaagcaccaattacaacccgtccctcaagagtcgactcaccatattagcagacttgtccaggaatcgcttctctctagaactaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtgggagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4216 JY8QFUQ01A78YS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 8 8.8.8 [1.17.38.11] CARGVPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggtcccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4217 JY8QFUQ01CDD8G productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4218 JY8QFUQ01B16GZ No results 4219 JY8QFUQ01AH7E6 No results 4220 JY8QFUQ01BIFZI unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 96 95.24 20/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcaccttaagtga 4221 JY8QFUQ01A0B86 productive Homsap IGHV3-33*02 F, or Homsap IGHV3-33*03 F 148 65.43 53/81 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 X X 14 X.X.14 [X.X.27.11] CATDDSNGWDEVADYW in-frame - gcctctggattcaccttcagctcccattggatgagctggatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4222 JY8QFUQ01BTH6E unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD6-13*01 F 2 X X X X.X.X [X.X.28.11] CVKDRKGSNWYYFEN## out-of-frame + Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggcccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 4223 JY8QFUQ01DLXBB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 509 92.37 109/118 nt 8 8 X 8.8.X [1.17.5.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca 4224 JY8QFUQ01AKMZK productive Homsap IGHV3-7*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + tctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggattctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4225 JY8QFUQ01DRQX0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARGRIVSVGMSGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 86 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4226 JY8QFUQ01AL7AV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 846 88.02 191/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactctgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4227 JY8QFUQ01AEQWG No results 4228 JY8QFUQ01DHW5J No results 4229 JY8QFUQ01BLLMD productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4230 JY8QFUQ01CV6T1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift) tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacggtaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 4231 JY8QFUQ01DU4I8 No results 4232 JY8QFUQ01AOKIY productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4233 JY8QFUQ01AQYMH No results 4234 JY8QFUQ01CH5ZD No results 4235 JY8QFUQ01BQYEH productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc 4236 JY8QFUQ01CHECP No results 4237 JY8QFUQ01DCPGQ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.24 198/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKGRGYNDYGLDYW in-frame + ctctggattcaccttcagtgactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtgacagttattttatatgatggaagtagaaaatactatgcagactccgtgaagggccgattcgccatctccagagacgtttcgaggaacacgttgtatctgcagatgaatagcctgagacctgaggacacggctgtatactactgcgcgaaaggacgtggatataatgactacggcctcgactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtctcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 4238 JY8QFUQ01B3N8H productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 4239 JY8QFUQ01DSHP5 productive (see comment) Homsap IGHV4-59*02 F 899 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD1-26*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARGGSGGAYWNLIRDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 108 to 119 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagaggtgggtccggtggggcctactggaatctgatccgggactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4240 JY8QFUQ01A4D36 productive (see comment) Homsap IGHV4-61*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [0.17.37.11] CARNPSYSNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 113 in the user submitted sequence), (cause frameshift) ctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaaccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4241 JY8QFUQ01C7YVI No results 4242 JY8QFUQ01B1TWL No results 4243 JY8QFUQ01AV6UJ No results 4244 JY8QFUQ01ATA76 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFLTTG in-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttgactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4245 JY8QFUQ01A68R4 No results 4246 JY8QFUQ01BWBBF No results 4247 JY8QFUQ01DF0UH No results 4248 JY8QFUQ01CPHAF No results 4249 JY8QFUQ01DPUG7 No results 4250 JY8QFUQ01DS4KK unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*06 F 796 85.19 184/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. gtctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagtcccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacatgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggactcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4251 JY8QFUQ01AE4IA No results 4252 JY8QFUQ01BPN3H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame + ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4253 JY8QFUQ01CL6BN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggtccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4254 JY8QFUQ01AT12H No results 4255 JY8QFUQ01BLAOP productive Homsap IGHV3-30*10 F (see comment) 724 81.94 177/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4256 JY8QFUQ01DOIL0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtgacggtgtcgtggaactca 4257 JY8QFUQ01DUKA9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGggcacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactcanttccccgaaccggtgacggtcgtgcgtggaactcag 4258 JY8QFUQ01BYE5H productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 770 85.65 179/209 nt 85.17 178/209 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 6 14 8.6.14 [X.17.38.11] CARERGSGPPTGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) gggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttcttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcggggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4259 JY8QFUQ01CDHQW productive (see comment) Homsap IGHV3-48*03 F 853 89.2 190/213 nt 87.79 187/213 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttcttatgcatgaactggtccgcctgtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 4260 JY8QFUQ01C1GO1 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4261 JY8QFUQ01CU1LQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4262 JY8QFUQ01DHUMB productive (see comment) Homsap IGHV1-2*02 F 785 85.85 182/212 nt 85.38 181/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.37.11] CARDWGGTYAPLDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 197 in the user submitted sequence), (cause frameshift) tggatacattttcaccggctactatatacattgggtgcgacaggccgctggacaagggcttgagtggatgggatacatcgacccttacagaggtgacacaaggtttgcagagaaatttcagggcagggtcaccttgaccagagacacgtccatcagtacagcctacatggaaatgaccggcctgacgtctgaggacggccatcttttactgtgcgagagattggggtggcacgtacgcaccgcttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4263 JY8QFUQ01AY2ED unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 432 77.78 112/144 nt 8 8 X 8.8.X [1.17.13.X] null + No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccc 4264 JY8QFUQ01CVUGR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 786 85.51 183/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [0.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag 4265 JY8QFUQ01ANN07 productive (see comment) Homsap IGHV4-4*07 F 844 88.73 189/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 7 11 8.7.11 [1.17.37.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGCAC' (6 nucleotides at position 22 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) ctctggtgtcgccaccagtagTGGCACttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtatTtactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctcaggagcacctccgagancacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4266 JY8QFUQ01A7QYN No results 4267 JY8QFUQ01BA9KM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccGagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4268 JY8QFUQ01DNJKW No results 4269 JY8QFUQ01A7C84 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 940 93.06 201/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'CAG' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggatgggtcCAGtctggtTattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4270 JY8QFUQ01DUX6F productive Homsap IGHV3-11*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVRDGARRTNQWLAHDFW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagctttaatgccttctatatgggttgggtccgccaggctccaggaaaggggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcancgctgcctggtcagggcttcttccc 4271 JY8QFUQ01DJILO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 8 9 7.8.9 [1.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4272 JY8QFUQ01C3R6B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + cctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 4273 JY8QFUQ01AZ2OV productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 860 88.53 193/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + cctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4274 JY8QFUQ01AE3KX No results 4275 JY8QFUQ01CHVDW productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4276 JY8QFUQ01DTEQ6 No results 4277 JY8QFUQ01BNJV1 No results 4278 JY8QFUQ01CJLZD No results 4279 JY8QFUQ01DXF7R productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4280 JY8QFUQ01DAGZ3 No results 4281 JY8QFUQ01AG95A No results 4282 JY8QFUQ01BECR8 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 83.8 181/216 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag 4283 JY8QFUQ01CT0C1 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [1.17.38.11] CARGGGGKSIPLDNW in-frame + gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4284 JY8QFUQ01DUQPM productive (see comment) Homsap IGHV4-61*02 F 986 94.95 207/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-10*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARGSGTYYNPMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'ACTG' (4 nucleotides at position 34 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tttctggtgcctccatcagcagtggtagttactACTGgggactggatccggcagcccgccgggaagggactggagtggattgggcgtatccataccagtgggggAcaccaactacaccccctccctcaagagtcgactcaccatatcagtagacgcgtccaagaaccaggtctccctgaggctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggttcggggacttattacaaccctatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 4285 JY8QFUQ01BY39E productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4286 JY8QFUQ01BHPUL No results 4287 JY8QFUQ01DJ6ES productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F 486 94.5 103/109 nt 92.66 101/109 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 X 15 8.X.15 [1.16.10.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 106 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagTcccccagggaagggcctggagtggattggttaaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4288 JY8QFUQ01B7RGK No results 4289 JY8QFUQ01CZK7C productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD6-19*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAGAEAGLLTYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgacgtactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 4290 JY8QFUQ01DSLQR unproductive (see comment) Homsap IGHV3-43*01 F 999 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAK**DWVLVLL*PL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaatgataggattgggtccttgtactactttgaccactggggccaggggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcc 4291 JY8QFUQ01A9QSI No results 4292 JY8QFUQ01C85OD No results 4293 JY8QFUQ01BGZM8 No results 4294 JY8QFUQ01BYFP6 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 4295 JY8QFUQ01BHC1U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD5-12*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARDGSAHSSIYHYYYGMDVW in-frame - ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtctcaaccattggtactagaggtagatccatatactacgcggactcagtgaagggccgattcaccacctccagagacaacgccaagaaatcactttatctggatatgcacagcctgagagccgaggacacggctatctattactgtgcgagagatggcagtgcacactcgtcgatctatcattactattacggcatggacgtctggggccaagggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4296 JY8QFUQ01A4PHC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSSGG# out-of-frame + ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtggggggggaccaggggacccctggtcaccgtctcctcagcatcccctgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4297 JY8QFUQ01CR7MJ No results 4298 JY8QFUQ01BDCL8 No results 4299 JY8QFUQ01C33A4 productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4300 JY8QFUQ01DKOPH No results 4301 JY8QFUQ01BCKHU No results 4302 JY8QFUQ01CVL8I No results 4303 JY8QFUQ01CM840 No results 4304 JY8QFUQ01BXQ3T No results 4305 JY8QFUQ01DUUTN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggttcctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 4306 JY8QFUQ01CLSTN productive (see comment) Homsap IGHV1-69*02 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD2-8*01 F 2 8 8 20 8.8.20 [0.17.38.11] CARGYCTNGVCYRGSYNWLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggaggcccctccggcagttataccatcaactgggtgcgacaggCcccctggacaagaccttgagtggatgggaaggatcatccctacccttggcatagtaaactacgcacagaagttccagagcagagtaacgattaccgcggacaagtggacgagcacaatcttcatggagctgagcaacctgagacctgaggacacggccgtgtattattgtgcgagaggatattgtactaatggtgtgtgttatcgcggctcgtacaactggctcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4307 JY8QFUQ01AFV38 No results 4308 JY8QFUQ01A6HOT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4309 JY8QFUQ01AT40O No results 4310 JY8QFUQ01AZ2OO No results 4311 JY8QFUQ01DWGDY unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRRGMVAGRYD##FDIW out-of-frame - stop codons in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgaacCtgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgccttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4312 JY8QFUQ01ASYKF No results 4313 JY8QFUQ01CWHMR No results 4314 JY8QFUQ01AS3UT unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4315 JY8QFUQ01BN6SA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDAFDL# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtgggccaagggacagtggtcaatgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4316 JY8QFUQ01DLJ3Q productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1069 98.2 218/222 nt 97.75 217/222 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD5-18*01 F 3 8 10 19 8.10.19 [1.17.37.11] CTTDYGGYSYGFAGMRAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggattcactttcaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgttttaaaagcaaaactgatggtggggcaacagactacgcttcacccgtgaaaggcagattcaccatctcaagagatgattcaaaaacacgctgtatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccactgactacggtggatacagctatggttttgcggggatgcgcgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4317 JY8QFUQ01BJ0Q1 No results 4318 JY8QFUQ01BW1R0 No results 4319 JY8QFUQ01CTGCU No results 4320 JY8QFUQ01C3JQ3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4321 JY8QFUQ01BYP7W No results 4322 JY8QFUQ01ATVY4 unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4323 JY8QFUQ01AYZBR productive (see comment) Homsap IGHV3-9*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKDMQGVGDIAIGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctggattcagccttgatgattatgccatgaactgggtccggcaagctccagggaaTgggcctggagtgggtctcatttatcagttggaatagtggtattatagcctatgcggactctgttaagggccgcttcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagcctgagacctgaagacacggctttgtattactgtgtaaaagatatgcaaggagtcggggacatagcgattggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4324 JY8QFUQ01AVUES No results 4325 JY8QFUQ01APS2Q unknown (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4326 JY8QFUQ01AL95Z productive Homsap IGHV3-7*01 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - gcctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4327 JY8QFUQ01CXG7S No results 4328 JY8QFUQ01BYGTR No results 4329 JY8QFUQ01BV3K1 productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame + tggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4330 JY8QFUQ01A6013 No results 4331 JY8QFUQ01ABGJ8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4332 JY8QFUQ01AI6N9 productive (see comment) Homsap IGHV3-48*01 F (see comment) 753 84.36 178/211 nt 83.41 176/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) tggattcaccttcggaacctatggcCatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4333 JY8QFUQ01BXJV2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 643 77.31 167/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag 4334 JY8QFUQ01AHKVZ No results 4335 JY8QFUQ01DRF8N No results 4336 JY8QFUQ01AZZUP productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 919 91.32 200/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - gcctctggatttaccttcagtggctatggcgtgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4337 JY8QFUQ01BK5AV unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 4338 JY8QFUQ01AZ72P productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 21 8.8.21 [0.16.38.11] CARGWLTAADTGVASGHDWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tggatacaccttcaccagctactatatgcactggatacgacaggcccctggacaaggcttgagtggatgggaataatcaaccctagtggtggtaccacaaggtacgcacagaagttccagggcagagtcttcatgaccagagacacgtccacgagcacagtccacatggaggtgaacggcgtaagatctgacgacacggccgtgtattactgtgcccgagggtggctgacagcagctgataccggggtggcgtcagggcacgattggttcgactcctggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4339 JY8QFUQ01DF7F3 No results 4340 JY8QFUQ01DQQU9 No results 4341 JY8QFUQ01CDRDN No results 4342 JY8QFUQ01A04MA No results 4343 JY8QFUQ01AJY9D No results 4344 JY8QFUQ01AF4NQ No results 4345 JY8QFUQ01AI1BW No results 4346 JY8QFUQ01B0MWW unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 4347 JY8QFUQ01CN403 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 939 93.46 200/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 2 8 7 10 8.7.10 [1.17.38.11] CARDASGWFDRW in-frame + ctctggtggctccatcagcggtttctactggaactggatccggcagcccccagggaagggactggagtggattgggtttatccattccagtgggagcaccgactacaatgcctccctcaagagtcgagtcaccatgtcagtagacacgtccaagcaccagttctccctgaggctgagctctgtaaccgctgcggacacggccgtgtattactgtgcgagagatgcctcaggctggttcgaccgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctcaagatgggaacgtggtcgtcgcatgcctggtccaggcttcttccccca 4348 JY8QFUQ01DBG2T unknown (see comment) Homsap IGHV3-7*01 F 1026 96.77 210/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccgag 4349 JY8QFUQ01CZ44B No results 4350 JY8QFUQ01B54RP No results 4351 JY8QFUQ01BD8JG No results 4352 JY8QFUQ01BYVUD productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD2-8*01 F 3 7 8 10 7.8.10 [1.16.38.11] CAREVSDAFEMW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) tctggattcatctttgatgatttggcatgaattggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4353 JY8QFUQ01CIDTD productive Homsap IGHV3-66*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccccttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4354 JY8QFUQ01ADNPS productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPRSVSRYSLFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatttttgtgcgagagatcctcgttccgtgagcaggtactctttatttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4355 JY8QFUQ01BA89B No results 4356 JY8QFUQ01CHBDO productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4357 JY8QFUQ01AHW9S productive Homsap IGHV3-11*01 F 913 91.67 198/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARADCDDACYIINSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaacttactgtatctgcaaatgaacggtctgagaactgacgacacggccttctattattgtgcgagagccgattgtgacgatgcctgctacataattaactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4358 JY8QFUQ01BFAXK productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 393 91.49 86/94 nt 90.43 85/94 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccctggcaccctcctcaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4359 JY8QFUQ01DA04L productive (see comment) Homsap IGHV3-23*05 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [2.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) agcctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4360 JY8QFUQ01A4SRM No results 4361 JY8QFUQ01BQPRR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4362 JY8QFUQ01CUTLJ productive Homsap IGHV3-7*01 F 975 95.33 204/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAKGGGNGDLDYW in-frame - tggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4363 JY8QFUQ01B28XE unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 85 62.26 33/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + stop codons ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcaagattcggcccacttactcgacctgactactggggcccagggtaactttggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4364 JY8QFUQ01CJDFB productive (see comment) Homsap IGHV3-7*01 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4365 JY8QFUQ01B9W5S No results 4366 JY8QFUQ01DFK28 No results 4367 JY8QFUQ01C5NXR No results 4368 JY8QFUQ01CK1GE No results 4369 JY8QFUQ01DTPH2 No results 4370 JY8QFUQ01BJ1UU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggccaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4371 JY8QFUQ01C2CQM No results 4372 JY8QFUQ01DBCQJ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4373 JY8QFUQ01CCLE2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4374 JY8QFUQ01DD6ZQ productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4375 JY8QFUQ01BET5U No results 4376 JY8QFUQ01COX6B No results 4377 JY8QFUQ01BGQVH No results 4378 JY8QFUQ01CLSNL productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 818 86.98 187/215 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVGVGVGSSVSFQYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactgtcaataacaactacatgggttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacactttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4379 JY8QFUQ01AUVES No results 4380 JY8QFUQ01AO9JD unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgaaccggtgacggtgtcgtggaactcag 4381 JY8QFUQ01BK60E No results 4382 JY8QFUQ01C4PDI No results 4383 JY8QFUQ01CKO6K No results 4384 JY8QFUQ01BDCRM No results 4385 JY8QFUQ01BOEKT unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 126 54.81 74/135 nt 8 8 X 8.8.X [2.17.10.X] null - No rearrangement found gcctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 4386 JY8QFUQ01BVKEQ No results 4387 JY8QFUQ01CZSZQ No results 4388 JY8QFUQ01ANV1B unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CMNELGYCSGG# out-of-frame - in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtaccaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaaAtttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4389 JY8QFUQ01AVP8E productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4390 JY8QFUQ01AVPBF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4391 JY8QFUQ01BO6U2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4392 JY8QFUQ01CK7KF No results 4393 JY8QFUQ01A3N6V No results 4394 JY8QFUQ01APYTK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 39 to 40 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); atgtctggattcacAgtttagaagctattccatgaattTGgggtccgccaggctccagggaaggggctggagtgggtctccgctgttagtgataCctggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4395 JY8QFUQ01BG7PE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDPGNYWGYYYDSW in-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctgggaaccctggtcgccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4396 JY8QFUQ01CA7GK productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CATSPSVGSTTVGYW in-frame + ctctggattcacctttagaaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgacagatggaggtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgccacatcccctagcgtgggatctacgacggtgggctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4397 JY8QFUQ01ABJ2H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 320 72.44 92/127 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (72,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccagggaaggggttggagtgggtctcatctattagtactagtggtcatcgcctgcctggtccagggcttcttccccca 4398 JY8QFUQ01AEX25 productive (see comment) Homsap IGHV3-11*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4399 JY8QFUQ01C0WB8 No results 4400 JY8QFUQ01CGRI4 No results 4401 JY8QFUQ01AOVXH unproductive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CLAEVGGRQFDN## out-of-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccaggggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4402 JY8QFUQ01BSYCR No results 4403 JY8QFUQ01CS0U6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4404 JY8QFUQ01AQUGR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4405 JY8QFUQ01DE7BX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4406 JY8QFUQ01BEJQP productive Homsap IGHV4-61*02 F (see comment) 681 79.09 174/220 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARERDRSIGGASELDSW in-frame + Low V-REGION identity (79,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctcttctgtccccataagcagtggtggttactattggaactggatccggcagcccgccgggaaggggctggagtggatcggacgtgttgacagtaatgggttcgtcaggtacaacagttccctcaagagtcgactttctatgtcggtggacatgtccaagagtcaggtctccctgaggttgaggtctgtgatcgccgcggacacggccgtatactattgtgcgcgagaacgcgataggtcgattggcggagcgtcagaacttgactcctggggccagggatctctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 4407 JY8QFUQ01A1YIH productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4408 JY8QFUQ01B3ND5 No results 4409 JY8QFUQ01DU4YB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4410 JY8QFUQ01CRGJG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgtgtcgtggaact 4411 JY8QFUQ01BINTP unknown (see comment) Homsap IGHV3-64*03 F, or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 169 58.78 77/131 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttccc 4412 JY8QFUQ01CZQLG No results 4413 JY8QFUQ01BUEG5 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 591 95.38 124/130 nt 94.62 123/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 X 11 8.X.11 [1.3.31.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4414 JY8QFUQ01AWQNO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 656 78.14 168/215 nt 76.74 165/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (78,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'CG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccCaggggagggggCGtggagtgggtcgcagattctgtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag 4415 JY8QFUQ01A6QI8 No results 4416 JY8QFUQ01CUORM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4417 JY8QFUQ01DIBA9 No results 4418 JY8QFUQ01B7IH4 No results 4419 JY8QFUQ01BZUOB productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4420 JY8QFUQ01DTZGD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD6-25*01 F 1 8 8 8 8.8.8 [1.17.38.11] CAKFPSISGW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaattcccctctatcagtggctggtacacgccaaaactggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 4421 JY8QFUQ01A3CVF productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-74*03 F (see comment) 393 78.46 102/130 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 X 5 17 X.5.17 [X.X.38.11] CVRDSSPSGYARYESMDVW in-frame + Low V-REGION identity (78,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagcctcacttcctatggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtagcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagtggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcagg 4422 JY8QFUQ01CJR1R productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); ttctggaGtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4423 JY8QFUQ01C0YWV productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 922 90.22 203/225 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 10 22 8.10.22 [2.17.38.11] CATDRPYYKNAAGRLWYYYGMDVW in-frame - tgctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4424 JY8QFUQ01C9GA0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1017 96.77 210/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctggattcagttttagttcttatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4425 JY8QFUQ01BFMSP No results 4426 JY8QFUQ01BXBXN unknown (see comment) Homsap IGHV3-23*05 F 92 54.37 56/103 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons tctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4427 JY8QFUQ01B54JA No results 4428 JY8QFUQ01AF3OP No results 4429 JY8QFUQ01DCEOK unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 845 88.37 190/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 2 7 8 X 7.8.X [1.17.38.11] CASFRVLESGY## out-of-frame - in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) tctggattcacattcggagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4430 JY8QFUQ01DQ43M No results 4431 JY8QFUQ01CO8R0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtctctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcttctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttccca 4432 JY8QFUQ01A2FAU productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4433 JY8QFUQ01BUBB2 productive Homsap IGHV3-9*01 F 1053 98.62 214/217 nt Homsap IGHJ6*02 F (see comment) 265 91.94 57/62 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CAKETTLTHPYYDYAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagcataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagctctgaggacacggccttgtattactgtgcaaaggaaactacactgacgcatccctactacgactacgctatggacgtctggggccaggggaccacggtcaccgtctcctcagggagtgcatccgccccaaccc 4434 JY8QFUQ01CYYF8 productive Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaagg 4435 JY8QFUQ01A7WE6 No results 4436 JY8QFUQ01DLG3Q No results 4437 JY8QFUQ01CLBE1 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 83 51.54 67/130 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4438 JY8QFUQ01DUBJT unproductive (see comment) Homsap IGHV4-61*02 F 1005 95.45 210/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 2 10 7 X 10.7.X [1.16.38.11] CARAGKQDFLEWLF#DDW out-of-frame - stop codons in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggtggctccatcggcagtggtagttattactggagctggatccgcagcccgccgggaagggactggaataccttgggcgtatctataccagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggactttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4439 JY8QFUQ01CWM41 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4440 JY8QFUQ01B33QK productive (see comment) Homsap IGHV4-61*02 F (see comment) 779 84.4 184/218 nt 83.03 181/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'CTT' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) tctctggtgcctccatcactagtggtaCTTactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactgggagcacctattacaaTcccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4441 JY8QFUQ01ARVQK No results 4442 JY8QFUQ01CN1JX No results 4443 JY8QFUQ01BQ1Q3 No results 4444 JY8QFUQ01DJHPC No results 4445 JY8QFUQ01BODJI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4446 JY8QFUQ01B9FB8 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 762 83.18 183/220 nt 82.73 182/220 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-3*01 F 1 10 7 X 10.7.X [1.17.37.11] CARRWSGTYPFAS# out-of-frame - Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagtcccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggcttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctgggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4447 JY8QFUQ01AVK6F productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4448 JY8QFUQ01CPETI No results 4449 JY8QFUQ01ALJH7 No results 4450 JY8QFUQ01BBE54 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaaGcagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4451 JY8QFUQ01B85AM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4452 JY8QFUQ01DKDK7 No results 4453 JY8QFUQ01DRSWV No results 4454 JY8QFUQ01AFRNE unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 705 91.07 153/168 nt 8 8 X 8.8.X [X.17.23.X] null + No rearrangement found ggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctg 4455 JY8QFUQ01CG46A unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 4456 JY8QFUQ01DID0M productive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcCcccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4457 JY8QFUQ01AT1ET unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 606 75.7 162/214 nt 74.77 160/214 nt 7 8 X 7.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (75,70% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaagggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4458 JY8QFUQ01C26ES productive (see comment) Homsap IGHV4-4*07 F 844 88.73 189/213 nt 87.79 187/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 7 11 8.7.11 [1.17.37.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGCAC' (6 nucleotides at position 22 to 27 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) ctctggtgtcgccaccagtagTGGCACttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4459 JY8QFUQ01DBD5L productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 4460 JY8QFUQ01AL3HV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4461 JY8QFUQ01BV960 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVPGEHHSYYYGMNAW in-frame - gcctctggattcatctttactaactatgccatgagttgggtccgccaggctccagggaagggggctgagtgggtctcaactatcagtgccaatggaggcaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaactccaagaacacagtggatatgcaaatgaacagcctgaaagccgaggagacggccgtctattattgtgcgaaagtcttccaggtgcctggcgaacatcactcctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4462 JY8QFUQ01DOBPZ unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4463 JY8QFUQ01BUOBI No results 4464 JY8QFUQ01AN9G4 No results 4465 JY8QFUQ01C55O4 productive (see comment) Homsap IGHV3-11*01 F (see comment) 712 80.82 177/219 nt 79.91 175/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [2.17.38.11] CVRDRSRGIADPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); acctctggattcatcttcactgacttctggatgagttGgggtccgcctgactccagggaagggcctcgagtgggtttcgtttataagtgggagtggcaatagtgtctggtatgcagactctgtgaagggccgattcactatctccagggacaacgccaagaatttaatCatttttggagatgaacagcctgagagtcgaggactcggccacatattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4466 JY8QFUQ01DEFN6 No results 4467 JY8QFUQ01DPT7F unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPLYNWN#YFYYYGMDVW out-of-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtggaactca 4468 JY8QFUQ01CXGNA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGcctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4469 JY8QFUQ01AHYMR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 190 100.0 38/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggt 4470 JY8QFUQ01DBZNN productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 4471 JY8QFUQ01DI3WZ No results 4472 JY8QFUQ01BU96X No results 4473 JY8QFUQ01AQDC9 No results 4474 JY8QFUQ01B0L20 No results 4475 JY8QFUQ01CQB3G productive Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatcccctgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaag 4476 JY8QFUQ01B8LWB productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 4477 JY8QFUQ01BOPD4 No results 4478 JY8QFUQ01CX0BC productive Homsap IGHV3-7*01 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + tctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 4479 JY8QFUQ01C8ASE productive Homsap IGHV3-48*03 F 792 85.25 185/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame - ctctggattcgccttcaaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4480 JY8QFUQ01CJ77N No results 4481 JY8QFUQ01AD2TV No results 4482 JY8QFUQ01BWW8O productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctaCctggagctggatccggcagTcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4483 JY8QFUQ01C2XJR productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4484 JY8QFUQ01AVLXC No results 4485 JY8QFUQ01CGGWD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 4486 JY8QFUQ01A942D No results 4487 JY8QFUQ01AHP3S productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccgctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 4488 JY8QFUQ01DOREV productive Homsap IGHV3-11*01 F 114 61.84 47/76 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.25.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ccggattcactttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4489 JY8QFUQ01A9V5D productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 4490 JY8QFUQ01B2FPL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 877 89.81 194/216 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAARIDSGHYWNAFDIW in-frame - tctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagaccttggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4491 JY8QFUQ01BB098 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.37.11] CANEVGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4492 JY8QFUQ01BW8IT productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.37.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 182 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4493 JY8QFUQ01B07DP unproductive Homsap IGHV3-7*01 F 887 89.45 195/218 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVVSSGWLFHY## out-of-frame + cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactgggggccagggctcccgggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4494 JY8QFUQ01CNNJJ productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.16.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4495 JY8QFUQ01B4D86 No results 4496 JY8QFUQ01A3R50 unproductive Homsap IGHV4-39*02 F (see comment) 762 83.18 183/220 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggtcgtcgtggaactcag 4497 JY8QFUQ01DAQHJ unproductive Homsap IGHV3-11*01 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDPYCSSTNCYPY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggatTtcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4498 JY8QFUQ01A4RES No results 4499 JY8QFUQ01DS3ZC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4500 JY8QFUQ01A92C9 productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 784 86.19 181/210 nt 84.76 178/210 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [X.16.37.11] CAKHPLRSTSGHSYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 2 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) ggatacatattcaccgacctttatatacactgggtgcgacaggcccctgacaagggcttgagtggatCgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcgggcaggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4501 JY8QFUQ01AI5JW productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4502 JY8QFUQ01BJH23 No results 4503 JY8QFUQ01A9XW7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 316 60.27 132/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - stop codons no junction found Low V-REGION identity (60,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gcctctggattcacatttagcaactatgccatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactcgtatattattgtgcgaaagagatagcagtgagtggtgaggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4504 JY8QFUQ01DUXII No results 4505 JY8QFUQ01CPIP8 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4506 JY8QFUQ01DCXHM unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 413 80.8 101/125 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4507 JY8QFUQ01C21XG unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 4508 JY8QFUQ01CWJQ8 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 297 59.45 129/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (59,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4509 JY8QFUQ01B6XM5 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctggatccgccaagctccggggagggcgtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4510 JY8QFUQ01BPWE6 No results 4511 JY8QFUQ01AJ3CD productive (see comment) Homsap IGHV3-NL1*01 F (see comment) 353 74.81 98/131 nt 74.05 97/131 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 X 5 14 X.5.14 [X.X.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (74,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcagctttttcaattatggcatgaactggggccgattcgccatctccagagacgattcgaGgggacacactgtatctccaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgaggggtagagatggtgttaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4512 JY8QFUQ01B6STP No results 4513 JY8QFUQ01BETLC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4514 JY8QFUQ01DFE9Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactcanttccccgaaccggtgacggtcgtgcgtggaactcag 4515 JY8QFUQ01CDOYZ No results 4516 JY8QFUQ01BMXPA unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found cctctggattcatcttcagtagctactggatgcactggg 4517 JY8QFUQ01CPU5E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4518 JY8QFUQ01C8PPT productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4519 JY8QFUQ01C0KOY productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 661 78.24 169/216 nt 77.31 167/216 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) gtctggtggctccatcgccacttatcattggtggAacttgggtccgccagaccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctgatcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4520 JY8QFUQ01AOJU2 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag 4521 JY8QFUQ01BX5TF No results 4522 JY8QFUQ01B3KFV No results 4523 JY8QFUQ01CRUFY No results 4524 JY8QFUQ01B8V2B No results 4525 JY8QFUQ01BHZ3N productive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatcccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4526 JY8QFUQ01CYMH8 No results 4527 JY8QFUQ01DK27R No results 4528 JY8QFUQ01BX0QN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAREGGRGSSSEDYFDYW in-frame + ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagagggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4529 JY8QFUQ01AW72P No results 4530 JY8QFUQ01C8XQH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.16.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctgtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4531 JY8QFUQ01BY9RP No results 4532 JY8QFUQ01AXCGR productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4533 JY8QFUQ01CS9VK productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 773 83.04 186/224 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4534 JY8QFUQ01CWELI No results 4535 JY8QFUQ01AFRYK No results 4536 JY8QFUQ01BO2RQ No results 4537 JY8QFUQ01CMN6I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctgggttcaccttcagtcgttatagcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggtcttctactgacatatattatgcagactcagtgaagggccgattcaccatttccagagacaacgccaagaactcactgttcctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4538 JY8QFUQ01B3WLK No results 4539 JY8QFUQ01B38SJ unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDLFQVSTTYFDY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactgggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaaactc 4540 JY8QFUQ01BKK0T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 437 93.0 93/100 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found tctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 4541 JY8QFUQ01ANCB8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4542 JY8QFUQ01A9WJB No results 4543 JY8QFUQ01DRHLE productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4544 JY8QFUQ01BAAAQ No results 4545 JY8QFUQ01AKWHE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 792 84.79 184/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4546 JY8QFUQ01BDL7E productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4547 JY8QFUQ01DNGMS No results 4548 JY8QFUQ01CUHJM No results 4549 JY8QFUQ01DK466 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 596 86.62 136/157 nt 85.35 134/157 nt 8 8 X 8.8.X [0.16.19.X] null + No rearrangement found in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 74 to 76 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tcgggactcatgttagcagctatgccatgacctgggtccgccaggctccagggaagggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaac 4550 JY8QFUQ01C7GDH No results 4551 JY8QFUQ01B0Q4E unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLFI#NFDYW out-of-frame + stop codons ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttataacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4552 JY8QFUQ01AFYZD unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4553 JY8QFUQ01AVXMW No results 4554 JY8QFUQ01C3IKA productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 4555 JY8QFUQ01C58UH No results 4556 JY8QFUQ01DACGY No results 4557 JY8QFUQ01C4VWZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4558 JY8QFUQ01BF7W4 No results 4559 JY8QFUQ01AE7Y3 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 4560 JY8QFUQ01DWDNB unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 4561 JY8QFUQ01CYNJO No results 4562 JY8QFUQ01DLEZW productive (see comment) Homsap IGHV3-7*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARATNADVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 97 of V-REGION: 'N' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); ctctggattcacctttagggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccNgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgccagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttcccccg 4563 JY8QFUQ01BSOKW No results 4564 JY8QFUQ01DBBO3 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 691 80.75 172/213 nt 80.28 171/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 78 of V-REGION: 'AG' (2 nucleotides at position 134 to 135 in the user submitted sequence), (cause frameshift); tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcgaAGtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4565 JY8QFUQ01BE615 No results 4566 JY8QFUQ01CAYVD No results 4567 JY8QFUQ01BP9LD productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaaggggctggagtgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4568 JY8QFUQ01A9YBA No results 4569 JY8QFUQ01DNHHQ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARHEGYNSRYYYFGYW in-frame + tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4570 JY8QFUQ01ABEDS No results 4571 JY8QFUQ01AWGGY No results 4572 JY8QFUQ01A3FHH No results 4573 JY8QFUQ01DU7IU productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 4574 JY8QFUQ01C33AV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4575 JY8QFUQ01BUUH7 No results 4576 JY8QFUQ01AK2QD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVAVGMSGWFDPW in-frame + ctctggattcaccttcagtaactactggatgtattgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggcagtagcacaagctacggggactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttgggatgtcaggctggttcgacccttggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4577 JY8QFUQ01DSV8Y productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4578 JY8QFUQ01ALRTE unproductive Homsap IGHV3-66*02 F 898 91.55 195/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtgggtctCcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4579 JY8QFUQ01B75FR No results 4580 JY8QFUQ01BYGMF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 4581 JY8QFUQ01A3OFB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKPAPRGYSGDDIEFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctctggattcacctttaacaactatgccctgagttggttccgccaggctccagggaggggactggagtgggtctcagccgttagtggtagtggtgattatacatattacgcagactccgtgAaagggccggttcaccatttccagagacaattccaagaacacactgtggctgcaaatgaacagactgagagccgaagacacggccgtatattactgtgcgaagcctgccccccgtggatatagtggtgacgacattgagttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4582 JY8QFUQ01BIH1E No results 4583 JY8QFUQ01DKPSN No results 4584 JY8QFUQ01AIKKX No results 4585 JY8QFUQ01CG3LU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacaatctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4586 JY8QFUQ01B744Z No results 4587 JY8QFUQ01BNC27 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 131 96.43 27/28 nt 8 X X 8.X.X [1.X.X.X] null - No rearrangement found ctctgggttcacctttagcagctatgcc 4588 JY8QFUQ01CXWSD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + ctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4589 JY8QFUQ01B56VC productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.37.11] CTHLREEMSYEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4590 JY8QFUQ01CEB97 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 787 85.19 184/216 nt 84.72 183/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARRSGRDGGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 82 of V-REGION: 'G' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift); tctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacGgtttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4591 JY8QFUQ01BZ966 productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4592 JY8QFUQ01DTO1H No results 4593 JY8QFUQ01CUJHH No results 4594 JY8QFUQ01BTCL3 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame + ctctggattcaagtttgatgattccggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggaatggtggtaagacaggttatggagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgcntgacgcctcgacagcacccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcc 4595 JY8QFUQ01DAUI5 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 15 8.8.15 [0.17.38.11] CARQRGPGIGTVGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgcgacagagaggtcccggtatagggacagttggcttggactattggggccagggtaccctagtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4596 JY8QFUQ01C8CME productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4597 JY8QFUQ01BRAAE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSRGAPTGT#FDHW out-of-frame + ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcaggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4598 JY8QFUQ01BCWGQ No results 4599 JY8QFUQ01AX0WG productive Homsap IGHV3-30*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcaccctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca 4600 JY8QFUQ01AR3M4 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 4601 JY8QFUQ01AMLPV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGG# out-of-frame - ggctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4602 JY8QFUQ01DP1EJ productive (see comment) Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.73 189/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.16.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4603 JY8QFUQ01B7HZR productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4604 JY8QFUQ01A744W No results 4605 JY8QFUQ01BFKLI No results 4606 JY8QFUQ01DA5ZG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 962 94.42 203/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [0.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggcccaaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccca 4607 JY8QFUQ01CC2VB unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 796 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.38.11] CATYGRFSF#SLDYW out-of-frame + tctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctcccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4608 JY8QFUQ01ANF5H No results 4609 JY8QFUQ01CJ5A2 No results 4610 JY8QFUQ01C6UTW No results 4611 JY8QFUQ01AS4LQ No results 4612 JY8QFUQ01DTPMH productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4613 JY8QFUQ01DUKA3 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAGHLLGDPFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'T' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); gggttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctaTtcctggtgactctgacaccagatacagtccgCtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 4614 JY8QFUQ01AXJ22 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcagatttagcagctatgccatgagctgggtccgccagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4615 JY8QFUQ01AW69P unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4616 JY8QFUQ01AIWLS No results 4617 JY8QFUQ01DSIM2 No results 4618 JY8QFUQ01CVS2H unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFGGSYNLVAY## out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4619 JY8QFUQ01A4O68 No results 4620 JY8QFUQ01CBJ8O No results 4621 JY8QFUQ01BH6PY No results 4622 JY8QFUQ01DTY3T No results 4623 JY8QFUQ01CT148 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacaacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 4624 JY8QFUQ01AEZHH No results 4625 JY8QFUQ01AZUBY productive Homsap IGHV3-9*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-11*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKESGVTGATGFDFW in-frame + ctctgggttcaactttgatgcttatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattaattcgaatggtggtaacatagactatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaagtccctatatctgcaaatgaacagtctgagacctgaggacacggccttgtattactgtgcaaaagagtctggagtgactggcgcaactggatttgacttctggggccagggagccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttgcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 4626 JY8QFUQ01AVET2 productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame + ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4627 JY8QFUQ01C69T5 unproductive (see comment) Homsap IGHV3-66*02 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt Homsap IGHJ6*02 F (see comment) 192 80.0 48/60 nt Homsap IGHD3-3*02 F 1 8 7 X 8.7.X [2.16.38.11] CARH*W#YALDVW out-of-frame - stop codons Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) gtctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttattagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcattaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 4628 JY8QFUQ01BA5U7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4629 JY8QFUQ01CK4GI No results 4630 JY8QFUQ01CKJ8Y unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*02 F or Homsap IGHV3-33*05 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 144 56.3 76/135 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found tctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 4631 JY8QFUQ01BQ1LV unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 689 94.16 145/154 nt 8 8 X 8.8.X [2.17.16.X] null - No rearrangement found gcctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatg 4632 JY8QFUQ01AQBZ1 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4633 JY8QFUQ01AV3HD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4634 JY8QFUQ01AUXJ6 No results 4635 JY8QFUQ01AVEP9 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagcccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 4636 JY8QFUQ01C2MEG unknown (see comment) Homsap IGHV3-7*01 F 1002 96.73 207/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaacccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4637 JY8QFUQ01C28IZ No results 4638 JY8QFUQ01DGW1K No results 4639 JY8QFUQ01ANJ4I unknown (see comment) Homsap IGHV3-23*05 F 121 54.48 73/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcacctttagcaactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4640 JY8QFUQ01DO7YT No results 4641 JY8QFUQ01BZBYT No results 4642 JY8QFUQ01BCZ8G No results 4643 JY8QFUQ01AYAUS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgGggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4644 JY8QFUQ01AGWXH productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 4645 JY8QFUQ01AOV3G No results 4646 JY8QFUQ01ALMBP unproductive Homsap IGHV3-9*02 F (see comment) 733 82.41 178/216 nt 81.94 177/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 7 X 8.7.X [1.17.38.11] CVKDKDKVGATLAIIP#FDFW out-of-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) ctctggattcaaccccgaaaactttgccatgcactgggtccgacaagttccagggaagggcctgaagtgggtctcaggtataaattggaatggacgaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccaatttggggactgaggacacggccttctatttttgtgtgaaagataaggacaaagtgggggccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4647 JY8QFUQ01A6WHV unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found cctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 4648 JY8QFUQ01DHOIV No results 4649 JY8QFUQ01DXHZL No results 4650 JY8QFUQ01B5QSA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 4651 JY8QFUQ01CH0DW No results 4652 JY8QFUQ01CHRZT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcnacctgactactgggggcccagggaactttggtcaccgtcgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgccagcacccagccagatggaacgtggtcatcgcctgctggtccagggcttcttccccca 4653 JY8QFUQ01AZ96F No results 4654 JY8QFUQ01DLUBY No results 4655 JY8QFUQ01A9DTT productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.37.11] CATLRGGTFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttataCttaattatgttggggacaccgattacaaccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4656 JY8QFUQ01BZUYN No results 4657 JY8QFUQ01CX6VT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1020 97.66 209/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 4658 JY8QFUQ01DWS1A unknown (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 53 of V-REGION: 'TG' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtggggTGggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4659 JY8QFUQ01CC7RN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4660 JY8QFUQ01DW6R5 productive Homsap IGHV3-9*01 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgagggaccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4661 JY8QFUQ01BPWL9 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4662 JY8QFUQ01CAK86 No results 4663 JY8QFUQ01AUWPD No results 4664 JY8QFUQ01BWI2D productive Homsap IGHV3-30*01 F 819 86.64 188/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDFDTDDVGTYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcttcgatagttatgctctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttgtttcatatgatggaaaatataagcaatatgcagattctgtggagggccgattcaccatctccagagacaactccaagaacacaggatatctgcaaatgaacagcctgacatctgacgatacggctgtgtatttttgtgcgagagacttcgatactgacgacgtgggcacctactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4665 JY8QFUQ01B2HHQ No results 4666 JY8QFUQ01AQQIB No results 4667 JY8QFUQ01CKXD4 unproductive Homsap IGHV3-7*01 F 1012 96.76 209/216 nt 96.3 208/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFTRR#YW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4668 JY8QFUQ01BAP04 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4669 JY8QFUQ01CGWES No results 4670 JY8QFUQ01A6PW0 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggcaantca 4671 JY8QFUQ01DCD36 productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - gcctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4672 JY8QFUQ01DIE0Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggcccaggggaccacggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaa 4673 JY8QFUQ01AIZMG No results 4674 JY8QFUQ01DCCWO No results 4675 JY8QFUQ01DTB7M productive (see comment) Homsap IGHV4-4*07 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [2.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ggtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagccCcccactacaacccttccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccacttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4676 JY8QFUQ01A6I5I No results 4677 JY8QFUQ01DCHOK No results 4678 JY8QFUQ01C101D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CTGNGATSHW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 91 in the user submitted sequence), (do not cause frameshift) tctggattcacctttaacaccgaggccctgacctgggtccgccaggctccagggaaggggctggagtgggtctcagatattagagatagtggaagtaaattctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtacctgcaaatgagcagcctgagagccgaggacacggccgtatattactgtacgggtaatggtgcgacttcccactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4679 JY8QFUQ01DGQES No results 4680 JY8QFUQ01C9YSI No results 4681 JY8QFUQ01AQS9S productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 4682 JY8QFUQ01C92T9 productive (see comment) Homsap IGHV3-33*05 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaatgggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4683 JY8QFUQ01A29KU No results 4684 JY8QFUQ01CDA8Y No results 4685 JY8QFUQ01DRVM7 No results 4686 JY8QFUQ01DNU0M No results 4687 JY8QFUQ01BJGIP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 4688 JY8QFUQ01A9HX8 productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARGGGGVHDYW in-frame + ctctggattcacctttagtgactattacatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagccagatggaagtcagaaaaactatgtggactctgtgaagggccgattctccatctccagagacaacgccaagaactcactatatctgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgcgagagggggaggaggtgttcacgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 4689 JY8QFUQ01CX99C No results 4690 JY8QFUQ01CA0N1 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 854 88.84 191/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcgggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4691 JY8QFUQ01A6RCW unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 4692 JY8QFUQ01DO79G productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4693 JY8QFUQ01A9L1M productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1070 100.0 215/215 nt 99.53 214/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.16.38.11] CARDGIFGGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtattaatagtgatgggagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagacgggatttttggagggcttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa 4694 JY8QFUQ01BM63P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAIEHTLPSGQGLGIQYFW in-frame - agcctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattcaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4695 JY8QFUQ01A80HW productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4696 JY8QFUQ01AOEBD No results 4697 JY8QFUQ01DRPER productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 4698 JY8QFUQ01AT5YH productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4699 JY8QFUQ01APV5N unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + in FR3-IMGT at codon 102 of V-REGION: 'AAAAAAAAA' (9 nucleotides at position 209 to 217 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtaAAAAAAAAAtattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4700 JY8QFUQ01BIK2I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - gcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4701 JY8QFUQ01BLB0A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame - cgtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4702 JY8QFUQ01B7LF9 productive (see comment) Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 555 71.62 164/229 nt 71.18 163/229 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 3 8 7 15 8.7.15 [6.17.37.11] CARSVTSRRRGGDFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (71,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 226 in the user submitted sequence), (cause frameshift) tctccagtggcattgttaatggcgaaggttttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctagagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctggagttacagtctgtgaccgccgcagacacggccttatattttgtgcgaggagcgtgacaagtcggcggcggggcggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4703 JY8QFUQ01A7Y4R No results 4704 JY8QFUQ01ANJ9X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASDLGGQKSYW in-frame - ccgtcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 4705 JY8QFUQ01DIW8G No results 4706 JY8QFUQ01CBFBW productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 4707 JY8QFUQ01CCYS6 No results 4708 JY8QFUQ01AW6X6 No results 4709 JY8QFUQ01A7GVL productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 4710 JY8QFUQ01B98ZU No results 4711 JY8QFUQ01BEVYZ No results 4712 JY8QFUQ01BZOK5 No results 4713 JY8QFUQ01B3KH4 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4714 JY8QFUQ01CZ0DT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4715 JY8QFUQ01CP7VJ productive (see comment) Homsap IGHV4-39*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 10 7 12 10.7.12 [1.17.37.11] CASVTTVSMRMKYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 108 in the user submitted sequence), (do not cause frameshift) tctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatcgtgggagcacctacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4716 JY8QFUQ01A5Z82 No results 4717 JY8QFUQ01DWOVD No results 4718 JY8QFUQ01BJANJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4719 JY8QFUQ01ABNBE No results 4720 JY8QFUQ01BTS7A productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 973 92.11 210/228 nt 91.67 209/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [2.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4721 JY8QFUQ01C0VEL unknown (see comment) Homsap IGHV3-7*02 F 114 59.52 50/84 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4722 JY8QFUQ01C7CS6 No results 4723 JY8QFUQ01BEJXS productive (see comment) Homsap IGHV3-72*01 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 3 8 10 15 8.10.15 [1.16.38.11] CSRVGGWVGRADGFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggactcaccttcagtgcccagtacttagactgggtccgccaggctccaggaagggactggagtgggttggccgtattagaagcaaaactaacagttacaccacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattctacgaactcactgtatctgcaaatgaacagcctgaaaaccgaagacacggccgtgtactactgttctagagtcggcgggtgggtggggcgtgctgatggttttgatctgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4724 JY8QFUQ01DDXBA No results 4725 JY8QFUQ01A3LLN unproductive Homsap IGHV3-9*01 F 963 93.55 203/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDAMGGAGDWAAFGI## out-of-frame + ctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggcccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4726 JY8QFUQ01DM6JG productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*04 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-15*01 F 2 8 7 21 8.7.21 [1.17.38.11] CARRIQGHCRGGSCSRNNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtggttactactggagttggatccgccagcCccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaactcgtccctcaagagtcgagccaccatctcagtagacacgtccaagaagcagttgtccctgaacgtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacggattcaaggacattgtaggggtggtagttgctccaggaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 4727 JY8QFUQ01DGZIW No results 4728 JY8QFUQ01ACY54 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactgggggccagggagtcctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4729 JY8QFUQ01C8VP6 No results 4730 JY8QFUQ01BHFKT No results 4731 JY8QFUQ01DBO0T productive Homsap IGHV3-7*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4732 JY8QFUQ01CM5IX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4733 JY8QFUQ01DGSNM No results 4734 JY8QFUQ01CM23O productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca 4735 JY8QFUQ01BUFCX No results 4736 JY8QFUQ01BP8IU No results 4737 JY8QFUQ01DR8BR No results 4738 JY8QFUQ01DVFKE productive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.16.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctggagtgggtggccaacataaagGcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4739 JY8QFUQ01BTHPI No results 4740 JY8QFUQ01AKCJN No results 4741 JY8QFUQ01B73XN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4742 JY8QFUQ01AK2PL productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgGggtccgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaatgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 4743 JY8QFUQ01CIIEZ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 89 51.88 69/133 nt 8 8 X 8.8.X [X.17.11.X] null + No rearrangement found stop codons ggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagactgggaacgtggtacgtcgcatgcctggtccagggcttgcttccccca 4744 JY8QFUQ01CYISQ No results 4745 JY8QFUQ01DXGTX No results 4746 JY8QFUQ01BEN0N unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcagcctcacttcctatggcatgaactgg 4747 JY8QFUQ01DRQVG productive Homsap IGHV4-61*02 F (see comment) 655 77.48 172/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARERDRSIGGAAELDSW in-frame - Low V-REGION identity (77,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctccaatgtacccatcagtcgtggaggttactactggaattggatccggcaggccgccgggaaggggctggagtggcttggacgtgttgacagtaatggattcgtcaggtacaattcttccctcaaaagtcgcctttctatgtcactagacacgtccaagaatcagatctccctgatattgaggtctgtgatcgccgcagacacggccgtatatttctgtgcgagggagcgtgataggtcgatcggtggagcggcagaacttgactcctggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 4748 JY8QFUQ01DVBT5 unknown (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 90.13 201/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); ctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaGggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggtacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 4749 JY8QFUQ01AY08B productive (see comment) Homsap IGHV3-48*03 F 854 88.84 191/215 nt 87.91 189/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgcatgaactgggtccgcctggtcaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4750 JY8QFUQ01DH1Y5 No results 4751 JY8QFUQ01BTVCR No results 4752 JY8QFUQ01DIG78 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 458 73.03 130/178 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (73,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4753 JY8QFUQ01DW2E3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4754 JY8QFUQ01B027I No results 4755 JY8QFUQ01CYKIH No results 4756 JY8QFUQ01A9XEC No results 4757 JY8QFUQ01B62LK unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 858 87.0 194/223 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 2 8 10 X 8.10.X [1.17.38.11] VLGILLVIIDS#W out-of-frame - Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccatttcactgacgcctggatgacctgggtccgccaggctccggggagggggctggagtgggttggccgtattaaaagtaaaggtggtggtgggacagcagactatgctgcacccgtgaaaggcagattcgtcatctcaagagatgattcaaggaacacgatgtatctgcaaatgaacagcctaaagagtgaagacacagccatgtattttgtgcttgggatactactggttattatcgactcatgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4758 JY8QFUQ01CHI1P productive Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ6*02 F 130 67.74 42/62 nt Homsap IGHD1-26*01 F 3 8 8 17 8.8.17 [1.17.38.11] CVKEKYRRYSGIDYGVDVW in-frame + ctctggattcagcttctataactacatgatgcactgggtccgccgagttccagggaaggggctggagtgggtctctgttattagtagtgatgggagttacataaagtatgcggactccgtgaagggccggttcaccgtctccagagacaacgccaagagtacattgtatctgcaaatgagcagtctgagacccgaggactcggctgtatattactgtgtgaaagagaagtatcgacggtatagtgggatcgactacggtgtggacgtctggggccaaggggccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 4759 JY8QFUQ01BB2EM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4760 JY8QFUQ01BTNQZ unproductive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGHFR**WLFQP#LDHW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttcgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4761 JY8QFUQ01AUZ6A No results 4762 JY8QFUQ01DG4PX No results 4763 JY8QFUQ01CURPS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 787 85.19 184/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGSYRLQLESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctggattcacctttagtagctatggcatgagttgggtccgccagtctccaaataagggactggagtgggtcgcaggcattagtgcaaatggtggcagtataaattatctggacgccgtgaagggccggtttatcatctctagagacaattccaagaacacgttgtatctgcaaatggacagcctgacagtcgaggacacggccgtttattactgtgtgaaagatcgtgattttctttgggggagctatcgtcttcaacttgaatcttggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4764 JY8QFUQ01CPBVE unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaactcag 4765 JY8QFUQ01DR31P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt Homsap IGHJ4*02 F (see comment) 132 75.0 36/48 nt Homsap IGHD6-13*01 F 1 8 8 10 8.8.10 [2.17.38.11] CANEVGYCSSRG in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtcgggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4766 JY8QFUQ01C74ZU unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 804 86.45 185/214 nt 85.98 184/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tggatatgactttagcagattttggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctAttttttcagcagtctgagggcctcggacaccgccatgtatttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggtaccacggtcaccgtgtctccaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 4767 JY8QFUQ01BVQ9C productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD4-17*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDGDYENNYGMDVW in-frame + ctttggattcaccttcattagttatagcatgaactgggtccgccaggctccagggaaggggctggagtcaatttcatacattagtagtagcagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccatttattactgtgcgagagatggtgactacgaaaacaactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4768 JY8QFUQ01A27QT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4769 JY8QFUQ01AI64L No results 4770 JY8QFUQ01B392Y productive Homsap IGHV4-4*07 F (see comment) 519 70.91 156/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-1*01 F 2 8 7 16 8.7.16 [3.17.38.11] CARERISSGGGPRHLEPW in-frame + Low V-REGION identity (70,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cactggaggtccggtcaacagtaatgactgctcttggacatggatccgagagtccgccgggaggggactggagtggattggccgtgtccatatgaatggccagaccgactacaatccatccttcggcagtcgtctcgccatgtccattgacacagtcaagaatgaattctcccttcgaatggtctctgtgaccgccgcagacacggccctatattactgtgcgcgagaacgtataagttccggtggcgggccgagacaccttgaaccctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4771 JY8QFUQ01CHA0G No results 4772 JY8QFUQ01CJPSM productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaattacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4773 JY8QFUQ01B57SG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 86 57.53 42/73 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found cctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4774 JY8QFUQ01BP38R unproductive (see comment) Homsap IGHV4-61*02 F 925 90.58 202/223 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [2.17.38.11] CAREK**SV#NWFDPW out-of-frame - stop codons tgtctctggtgactccatcaccagtggnaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4775 JY8QFUQ01B8UMI No results 4776 JY8QFUQ01DRE5J unproductive Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4777 JY8QFUQ01BM0OX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 8 8.8.8 [1.17.38.11] CAKRYSLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttaagaactatgccttaaactgggtccgccaggctccagggaaggggctggagtgggtctccggaatcagtgctactggtgaaagcacacactacgcagactccgtaattggccggttcaccatctccagagacgattccaagaatacgttatatctgcaaatgaacagcctgagagccgaggacacggccgtatatttctgtgcgaaacgatattctcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4778 JY8QFUQ01CT3VW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDQRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcagcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4779 JY8QFUQ01C0YTX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4780 JY8QFUQ01A4M2O productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 7 8 17 7.8.17 [1.17.38.11] CARHSHSSGYSSLDALEIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 93 of V-REGION: 'C' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) tctgcatatagttttccagttactggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcaatcccggtgactctgataccagatatagcccgtcctttcaaggccaggtcaccgtctcagccgacaggtccatcagtaccgcctacctgcagtggaaaaCgcctgagggcctcggacaccgccatgtattactgtgcgcgacactcccacagtagtggttattccagccttgacgctcttgagatctggggccaagggacaatggtcaccgtctcttctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4781 JY8QFUQ01CM4V1 No results 4782 JY8QFUQ01AW5OJ unknown (see comment) Homsap IGHV1-2*05 F (see comment) 415 74.19 115/155 nt 8 8 X 8.8.X [0.17.18.X] null + No rearrangement found Low V-REGION identity (74,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4783 JY8QFUQ01BUX4M unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggccccccgcacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 4784 JY8QFUQ01DFNUL unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F (see comment) 263 70.54 79/112 nt 8 8 X 8.8.X [1.17.3.X] null + No rearrangement found Low V-REGION identity (70,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtcccaagatgggaacgtggtcgtcgcatgcctggtccaggg 4785 JY8QFUQ01COAZ0 productive (see comment) Homsap IGHV3-11*04 F 854 88.84 191/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.16.38.11] CAKDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcagtttcagtgactactacatgagttggatccgccaggctccagggaggggctggagtgggattcGatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4786 JY8QFUQ01BSYE7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg 4787 JY8QFUQ01CA1BC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [2.17.38.11] CANELGYCSGGG in-frame - gcctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4788 JY8QFUQ01DSFBK No results 4789 JY8QFUQ01C8BXD unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 271 57.99 127/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (57,99% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4790 JY8QFUQ01DA0XY No results 4791 JY8QFUQ01DM8ID unproductive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CAREGAWLHLQEV#FDYW out-of-frame + stop codons in CDR2-IMGT at codon 59 of V-REGION: 'ATT' (3 nucleotides at position 96 to 98 in the user submitted sequence), (do not cause frameshift); tctctgacgactccatcagcagtggcacttactactggagttggatccggcagcccgccgggaaggctccggagtggattggccgcttctatactATTactgggcgcaccaactacaatccctccctcgagagtcgagtcaccataacaagggacgtgtccaagaatcagttctccctgagactgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagggggcatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcaatgcctggtccagggcttc 4792 JY8QFUQ01A62TP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.16.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctgagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4793 JY8QFUQ01COJQ4 productive Homsap IGHV4-39*02 F (see comment) 758 82.81 183/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagaccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4794 JY8QFUQ01CCZ8Y No results 4795 JY8QFUQ01B0DYI No results 4796 JY8QFUQ01CCX0A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4797 JY8QFUQ01BI479 No results 4798 JY8QFUQ01AKY3V unproductive Homsap IGHV1-58*01 F 876 90.19 193/214 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [0.17.38.11] CAASASYNGYDTDAFDI## out-of-frame - tggattcacctttgattcctctgctgtgcagtgggtgcggcaggctagtggacaccgccttgagtggatgggatggatcgtcgttgccaatggtaagacagactacgcacggaatctccagggaagagtcaccattgccagggacatgtccacaagtacagtctacatggagctgagcagcctgaaatccgaggacacggccgtatattactgtgcggccagtgcttcgtataatggctacgatactgatgcttttgatatctgggggcgaagggacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4799 JY8QFUQ01AW796 No results 4800 JY8QFUQ01CI7M9 No results 4801 JY8QFUQ01AZEJK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 792 84.79 184/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4802 JY8QFUQ01A44QM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4803 JY8QFUQ01CA31J unknown (see comment) Homsap IGHV3-74*03 F 113 54.33 69/127 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4804 JY8QFUQ01APGRW productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CASGSGWTAEYW in-frame + ctctgaattcaccgttagcagtcattggatgaattgggtccgccaggctccagggaaggggctggaatgggtggccaacataaaacaagatgcaagtgagaaaaactatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaattcactgtatctgcaaatgaacagcctgagactcgaggacacggctgtgtatttctgtgcgagtggcagtggctggacagctgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4805 JY8QFUQ01C16AG unproductive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg 4806 JY8QFUQ01C5F9X unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01C5F9X ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4807 JY8QFUQ01CJB7R No results 4808 JY8QFUQ01B1QU5 No results 4809 JY8QFUQ01C80YW productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-16*02 F 3 8 7 9 8.7.9 [4.16.38.11] CARGDPIFMIV in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccattttcatgatagtgttaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4810 JY8QFUQ01CSJRH unproductive Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4811 JY8QFUQ01BNVAV productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4812 JY8QFUQ01CYTK2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4813 JY8QFUQ01DCD9M productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4814 JY8QFUQ01ATZY0 No results 4815 JY8QFUQ01C6VCR productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 4816 JY8QFUQ01BM12C productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4817 JY8QFUQ01A9IHK productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4818 JY8QFUQ01CR3K9 No results 4819 JY8QFUQ01B2YHD productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4820 JY8QFUQ01DDB3S No results 4821 JY8QFUQ01AFBN6 productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagCttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4822 JY8QFUQ01C4IRB No results 4823 JY8QFUQ01AX7OK productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame + ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg 4824 JY8QFUQ01ATIZV productive Homsap IGHV3-66*02 F 840 88.32 189/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-8*01 F 3 8 7 11 8.7.11 [1.17.38.11] CASHLMVYALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtggcaagtacatgagctgggtccgccaggctccagggcagggactggagtgggtctcagttatctatagtactggtagtacatactacgcagattccgtgaaagggcggttcaccatctccagagacagttccaacaacactctatatcttcaaatttacggcctgagagctgacgacacggctacttactactgtgcgagtcacttaatggtgtatgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4825 JY8QFUQ01BZ03R unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4826 JY8QFUQ01BRI6L productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4827 JY8QFUQ01CZ2QC No results 4828 JY8QFUQ01B2E25 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtccgtcgcctgcctggtccagggcttcttccccca 4829 JY8QFUQ01DHY7H No results 4830 JY8QFUQ01CT9XL No results 4831 JY8QFUQ01DWNCI No results 4832 JY8QFUQ01DQ9C2 productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4833 JY8QFUQ01CSXWT No results 4834 JY8QFUQ01AHOGJ No results 4835 JY8QFUQ01C2XOR No results 4836 JY8QFUQ01DTOOJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-25*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDLLGIAPAGHSLDHW in-frame + ctctggattcacctttggcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagaggtgaccacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacactgtttctgcaaatgaatagcctgggagtcgaggacacgaccgtatattactgtgcgaaggatcttctagggattgcgccggcgggccattcccttgaccactggggccagggaaccctggtcgccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggcaacgtggtcatcgcctgcctggtccagggcttctccccca 4837 JY8QFUQ01A4KFE No results 4838 JY8QFUQ01CUFWM productive Homsap IGHV3-30*01 F 909 91.24 198/217 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAREWAASHFDHW in-frame - cgctggattcaccttcagtggctttgctttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4839 JY8QFUQ01C7UBY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4840 JY8QFUQ01C15WM No results 4841 JY8QFUQ01BQWX0 No results 4842 JY8QFUQ01CJDXX unknown (see comment) Homsap IGHV1-2*02 F 487 86.72 111/128 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg 4843 JY8QFUQ01ADHHB No results 4844 JY8QFUQ01CJBPC No results 4845 JY8QFUQ01CMKK2 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 177 94.87 37/39 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttggttattatggcatgagctgggt 4846 JY8QFUQ01AZMLB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD1-20*01 F 3 8 8 19 8.8.19 [1.17.38.11] CANASPLYNWNVFLLLRYGRL in-frame + Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctgggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 4847 JY8QFUQ01CX0A5 unproductive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGDLTGVSVLL*Q*WFK#YW out-of-frame + stop codons tctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggtttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggccttcttcc 4848 JY8QFUQ01APCN7 No results 4849 JY8QFUQ01A3V0Z productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4850 JY8QFUQ01AQN7V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4851 JY8QFUQ01A0UL2 No results 4852 JY8QFUQ01CSQX1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CVRDRSGQAVGYW in-frame - ctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4853 JY8QFUQ01BCLAX productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4854 JY8QFUQ01ARBLC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagcaactGactggatgcactgggtccnccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4855 JY8QFUQ01AYSY2 No results 4856 JY8QFUQ01CN09R No results 4857 JY8QFUQ01C3SFA No results 4858 JY8QFUQ01CC1T7 No results 4859 JY8QFUQ01A62TI No results 4860 JY8QFUQ01BC3WS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 450 67.28 146/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (67,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4861 JY8QFUQ01B5T7P No results 4862 JY8QFUQ01DRIS4 No results 4863 JY8QFUQ01BBTEQ No results 4864 JY8QFUQ01ARLS0 No results 4865 JY8QFUQ01B13L2 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggatgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4866 JY8QFUQ01DAW7G unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggcccaagggacaatagtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcacctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4867 JY8QFUQ01CRHX1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 4868 JY8QFUQ01DNEWM productive (see comment) Homsap IGHV4-61*02 F 1001 95.02 210/221 nt 94.57 209/221 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD6-19*01 F 1 10 7 15 10.7.15 [1.17.38.11] CASTGYTSAPSEWMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtggttccatcaccagtggtatttactactggagctggctccggcagcccgccgGggaagggactggagtggattgggcgtatctatacctttgggagcaccaactacaacccctccctcaacagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaatctgaactctgtgaccgccgctgacacggccgtgtattactgtgcgagtaccggatataccagtgccccaagcgagtggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4869 JY8QFUQ01DH2KW unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 612 75.58 164/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4870 JY8QFUQ01B1SS2 unknown (see comment) Homsap IGHV4-61*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 9 7 X 9.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcagtagtggttttactactggagctggacccggcagcccgccgggaagggactggagtggattgggcgtgtccatagcggtggtagttccgactacaacccctccctcacgggtcgagtcaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgtgtatttctgtgcgagagaagcgcctgcctggtccagggcttcttccccca 4871 JY8QFUQ01BONZZ productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 947 94.34 200/212 nt 92.92 197/212 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 12 8.8.12 [0.16.38.11] CVRGNAVVAASDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) tggaggcaccttcagcagtcatgctatcagctgggtgcgacaggcccctgacaaggcttgagtggatgggcgggatcatAccctagctTttggtacaccaaactacgcacagaagttccagggcagagtcacgatgaccgcggacgaatccacgagcacagcctacatggagctgagcagcctcagatctgaagacacggccgtgtattattgtgtgagaggtaacgcggtggtagctgccagcgacgactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4872 JY8QFUQ01CMRCI unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFTRR#YW out-of-frame - ctctggattcaggtttagtatctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacggcctgagagccgaggacacggctgtatattactgtgcgataagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4873 JY8QFUQ01ANBSV No results 4874 JY8QFUQ01A3IDY unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat 4875 JY8QFUQ01CCM2O unproductive (see comment) Homsap IGHV3-7*03 F (see comment) 310 59.91 130/217 nt 59.45 129/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-8*02 F 2 8 8 X 8.8.X [1.17.38.11] V*EIVRVAGP#DYW out-of-frame - stop codons Low V-REGION identity (59,91% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcagttttagtgactttggatgcactgggtccgccaggcnccagggaaTggggctggagtgggtgggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4876 JY8QFUQ01BJO7P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4877 JY8QFUQ01CC43S productive Homsap IGHV3-7*01 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAISSGYYSTGYW in-frame - tggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4878 JY8QFUQ01CVE9T No results 4879 JY8QFUQ01A8R3E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); ctctggattcatgtttagtagctttcccatgggcCtgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4880 JY8QFUQ01BL72O productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.37.11] CAKDPFIAATGRPWYFEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) tctggattcaccttcagcagctatggcatgcactggttccgccaggctccaggcaaggggctggagtgggtggcagctatctcatatgatggaattgacaaatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaacacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgcccctggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4881 JY8QFUQ01BFSFW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 474 82.61 114/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 4882 JY8QFUQ01CO1XL No results 4883 JY8QFUQ01BKWMA No results 4884 JY8QFUQ01BC3EN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 772 95.81 160/167 nt 8 8 X 8.8.X [1.17.21.X] null + No rearrangement found tctggattcacctttagtagttatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcagctattagtggtagtggtggtagcacaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgta 4885 JY8QFUQ01DH4NU No results 4886 JY8QFUQ01DNZ96 productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca 4887 JY8QFUQ01ANVJX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4888 JY8QFUQ01DRPAB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4889 JY8QFUQ01DVLTJ No results 4890 JY8QFUQ01ATYER productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + tctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccccttggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4891 JY8QFUQ01CMRN2 No results 4892 JY8QFUQ01CQH36 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 4893 JY8QFUQ01A8KQW productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4894 JY8QFUQ01DUI4B unknown (see comment) Homsap IGHV3-9*01 F (see comment) 414 65.44 142/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (65,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactcttgtattattgtgcaaaatgatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4895 JY8QFUQ01B9U8I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 756 83.41 181/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatctagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 4896 JY8QFUQ01BUSG9 No results 4897 JY8QFUQ01BA3QB productive (see comment) Homsap IGHV3-7*01 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 7 8 12 7.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) tctaaattcactttagtaactattggatgaattgggtccgccaggctccagCggaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4898 JY8QFUQ01CT0JJ No results 4899 JY8QFUQ01DBSNF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4900 JY8QFUQ01CVAIB No results 4901 JY8QFUQ01BDH7F No results 4902 JY8QFUQ01BBA5R productive (see comment) Homsap IGHV3-74*03 F (see comment) 684 79.72 173/217 nt 78.8 171/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAMRFCGGPECYPYLDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'AA' (2 nucleotides at position 98 to 99 in the user submitted sequence), (cause frameshift); ctctgggttcacattcagtaactactggatccactgggtccgccaagctccaggaaaAGggggctagagtggggtcgcactattaatgatgctgggaAAgcgtgccgacttcgcgacatttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4903 JY8QFUQ01DPNYP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 176 58.82 80/136 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4904 JY8QFUQ01BESSR No results 4905 JY8QFUQ01C6JT1 No results 4906 JY8QFUQ01BBRHL unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDGGSYNRMDL## out-of-frame + gtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcaaggggctggagtggatggcaattatatggtatgatgggaaaaataaatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaattccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggcccagggaaccctggtcaccgtctcgtcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 4907 JY8QFUQ01BT9J3 No results 4908 JY8QFUQ01DDYOO unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 106 55.77 58/104 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4909 JY8QFUQ01CYXIH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 84 51.06 72/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found cctctggattcacctttagtagttctgccatgaactggaggagtctggggaggcttggttcagcgggcgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4910 JY8QFUQ01B4GDP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4911 JY8QFUQ01CZW8C unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga 4912 JY8QFUQ01B4U3Q unproductive Homsap IGHV3-13*01 F 903 91.59 196/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CAREVTRLTCPL#YLYFDLW out-of-frame + ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccggggacacggctgtttattattgtgcaagagaggtgactagacttacctgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4913 JY8QFUQ01A5HCP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 784 84.02 184/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4914 JY8QFUQ01CIZBF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGRFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaagatttgactactggggccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4915 JY8QFUQ01DP9ZJ unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 81.15 99/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctaTcgcagagtctgtta 4916 JY8QFUQ01A53VQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4917 JY8QFUQ01A7GLV productive Homsap IGHV4-61*02 F 821 85.97 190/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.38.11] CAREDYYGSGSYGRAWFDSW in-frame + tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtagtcatcgcctgcctggtccagggcttcttccc 4918 JY8QFUQ01AZ3JL productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4919 JY8QFUQ01B0NWJ No results 4920 JY8QFUQ01CU1G4 No results 4921 JY8QFUQ01CZEKC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacaacctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4922 JY8QFUQ01C4HOJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 558 72.81 158/217 nt Homsap IGHJ1*01 F (see comment) 19 63.64 7/11 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (72,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity). The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 4923 JY8QFUQ01A2YCO productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 924 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 13 8.8.13 [2.17.38.11] CATGAGNWNYIFNYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); ggcctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgGgtttttatatatactacgcggattcagtgaagggccgagtcaccatctccagagacaacgccaagaattcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacatttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4924 JY8QFUQ01DMUDG unknown (see comment) Homsap IGHV3-7*01 F 1036 96.8 212/219 nt 95.89 210/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); gcctctggattcagGgtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgTtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4925 JY8QFUQ01BKQYS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4926 JY8QFUQ01DBMQB productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 255 77.27 68/88 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.29.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (77,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggaattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4927 JY8QFUQ01CO5D5 productive Homsap IGHV3-11*01 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDSW in-frame + ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgactcctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4928 JY8QFUQ01CTZFP productive Homsap IGHV3-64*02 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRPMAGFHGILYDNW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 4929 JY8QFUQ01CF9OG productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcaggaagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4930 JY8QFUQ01AZZ31 productive Homsap IGHV4-61*03 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + ccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 4931 JY8QFUQ01A6TCD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4932 JY8QFUQ01BXO87 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 133 63.64 49/77 nt 8 X X 8.X.X [1.16.X.X] null + No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 4933 JY8QFUQ01BSN89 No results 4934 JY8QFUQ01DG8S8 No results 4935 JY8QFUQ01AQXWF productive Homsap IGHV4-34*10 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + gtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4936 JY8QFUQ01DNBC3 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaTggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4937 JY8QFUQ01AJ891 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4938 JY8QFUQ01BIQ13 No results 4939 JY8QFUQ01BIV2N No results 4940 JY8QFUQ01ADYD0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4941 JY8QFUQ01CC158 No results 4942 JY8QFUQ01DSAE2 No results 4943 JY8QFUQ01AZR16 unproductive (see comment) Homsap IGHV3-9*01 F 810 86.18 187/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDI* in-frame + stop codons ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctgaggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4944 JY8QFUQ01CMDH5 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4945 JY8QFUQ01DXG6J unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 2 8 7 X 8.7.X [1.17.38.11] CGRGDG#LDLW out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtctctggtcttaatttgaatggtgccacaggttatgcaaagtccgtgacgggccggtttaccatctccagagacaacgccaagaactccctgtatttggaaatggatagtctgagagtcgaagacacggccttctattattgtgggagaggggacgggggttggacctctggggccggggaatcctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4946 JY8QFUQ01DSVVP No results 4947 JY8QFUQ01AARG7 No results 4948 JY8QFUQ01DWNBV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 942 92.27 203/220 nt 91.82 202/220 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); ggcctccggattcacctttagtagttactGggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4949 JY8QFUQ01CT6CG No results 4950 JY8QFUQ01BI4HP No results 4951 JY8QFUQ01AS0T2 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 639 93.79 136/145 nt 93.1 135/145 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [1.8.31.11] CARRDVGLHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 53 in the user submitted sequence), (do not cause frameshift) ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4952 JY8QFUQ01C1M8M productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 864 88.94 193/217 nt Homsap IGHJ1*01 F (see comment) 179 82.69 43/52 nt Homsap IGHD2-21*02 F 2 8 8 8 8.8.8 [1.17.38.11] CSSGGDYPNW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcgacttcgatggccgtgctatgcactgggtccgccaggctccaggcaagaggctggagtgggtggcagttatctcatatgatggaaatgataaaaactacgcagactccgtgaggggccgattcaccatctccagagacaattctaaggacacgctgtttttgcaaatgaacagcctgagacatgaagacacgggtgaatatttctgttcttcaggaggtgactacccgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 4953 JY8QFUQ01BRY9D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4954 JY8QFUQ01BJFVK productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4955 JY8QFUQ01C9D41 No results 4956 JY8QFUQ01ANCFE unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 99 59.72 43/72 nt 7 X X 7.X.X [X.17.X.X] null - No rearrangement found ttcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4957 JY8QFUQ01C4CSC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 4958 JY8QFUQ01DUQLJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4959 JY8QFUQ01AJXIE No results 4960 JY8QFUQ01AUT3T No results 4961 JY8QFUQ01CLHJ5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgccctggtccagggcttcttccccca 4962 JY8QFUQ01CBVVZ No results 4963 JY8QFUQ01B0C4K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4964 JY8QFUQ01A73JL No results 4965 JY8QFUQ01COSTG unknown (see comment) Homsap IGHV2-5*03 F 177 54.69 105/192 nt 10 7 X 10.7.X [9.17.26.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4966 JY8QFUQ01BXTHJ No results 4967 JY8QFUQ01DHXRX productive (see comment) Homsap IGHV3-48*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4968 JY8QFUQ01DDBVK No results 4969 JY8QFUQ01BJUHM productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFDYW in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacggccacgtattattgtgtgaggcgggtctggggatacagttatggttccgtttcgtattacttcgactactggggccagggaatcccggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4970 JY8QFUQ01AKQ8J No results 4971 JY8QFUQ01BMGFD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4972 JY8QFUQ01CT8IW No results 4973 JY8QFUQ01CAZRX No results 4974 JY8QFUQ01CBUH5 No results 4975 JY8QFUQ01B8GEV unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4976 JY8QFUQ01DGP7M unproductive Homsap IGHV1-3*01 F 616 95.56 129/135 nt 94.81 128/135 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD4-23*01 ORF 2 8 X X 8.X.X [X.3.34.11] CTRGRGRELPSQPYCS#PW out-of-frame + in FR2-IMGT, from codon 42 of V-REGION: 78 nucleotides (from position 34 in the user submitted sequence), (do not cause frameshift) ggatataccttcactagttatgctatacattggaacttccagggcagagtcaccattaccagggacacatccgcgagcacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtatttctgtacgagaggccgggggagggaacttccctcccaaccctattgttcgaccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgtctggtccagggcttcttccccca 4977 JY8QFUQ01BI23D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 4978 JY8QFUQ01CPTBR No results 4979 JY8QFUQ01BWF0D unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 4980 JY8QFUQ01CXV7T productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 4981 JY8QFUQ01DJCTM productive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagagcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4982 JY8QFUQ01C68H5 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 10 9 X 10.9.X [1.17.38.X] null + No rearrangement found tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggtagatatga 4983 JY8QFUQ01B2LAD productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 4984 JY8QFUQ01CLYHH productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4985 JY8QFUQ01CNRRQ No results 4986 JY8QFUQ01C50X0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVPGPNDNYFDYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagggacgacgacacggctgtctatttctgtgcgagagatgtcccgggccccaatgacaactactttgactactggggccagggaaccctgcttaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4987 JY8QFUQ01CCF3T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctgatcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 4988 JY8QFUQ01C8NJG No results 4989 JY8QFUQ01CI74R unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 360 63.77 132/207 nt 8 8 X 8.8.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (63,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtcaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4990 JY8QFUQ01BD3AU No results 4991 JY8QFUQ01DB4HA unproductive Homsap IGHV3-53*04 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 7 X 8.7.X [1.17.38.11] CARQTAPLG#FDLW out-of-frame - tctcggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttacttctgtgcgagacagactgcccctttgggaactttgacttatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4992 JY8QFUQ01ACOEQ productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30*10 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30-3*03 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [1.17.38.11] CARDLASFCGGDCPIDYW in-frame - cctctggatttcccttcagcaattacgctatgcactgggtccgccaggctctgggcaaggggctggagtgggtggcacttatttcgtatgatgggactaataaatactacatagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagacttgaggacacggctgtgtatttctgtgcgagagatctggcatcattttgtggtggtgactgccccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4993 JY8QFUQ01AUKC7 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4994 JY8QFUQ01AYEQ5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 482 68.81 150/218 nt 68.35 149/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (68,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaaggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4995 JY8QFUQ01BZBV8 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.69 196/221 nt Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.38.11] CTNDRSMAVRATH#FHIW out-of-frame - stop codons tctctggtgactccattggtagcagtgcctactactggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgctttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 4996 JY8QFUQ01DS9SP unknown (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F (see comment) 782 84.65 182/215 nt 83.72 180/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'GAAGCT' (6 nucleotides at position 25 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); tctctggaggctccatcagcagtgGAAGCTacttctggacctggatccggcagcccgccgggaaggatctggagtggattgggcgcttctacagtagtgacagtgtcgactacaaccccGtccctcaggggtcgagccaccatttcagcggacacgtccaagagccagttctcccttaatctgaagtctgcgaccgccgcagacacggccgtttattactgcgcgagagagaattactacggttcggggagttatgggcgggcctggtttgactactggggcccgggcaatccaggtcaccgtctctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 4997 JY8QFUQ01DIHKE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 4998 JY8QFUQ01DGMSO unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 4999 JY8QFUQ01DGY73 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5000 JY8QFUQ01DJCTZ No results 5001 JY8QFUQ01AJG6I No results 5002 JY8QFUQ01ASMT6 productive Homsap IGHV4-39*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 10 7 12 10.7.12 [1.17.38.11] CASVTTVSMRMKYW in-frame + ctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5003 JY8QFUQ01BTWEZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5004 JY8QFUQ01CBLDO No results 5005 JY8QFUQ01CUFUW productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtgtccatagcatGgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtgGgtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 5006 JY8QFUQ01C8MMO No results 5007 JY8QFUQ01B4V8L No results 5008 JY8QFUQ01ASEPQ productive Homsap IGHV3-66*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [2.17.38.11] CARQTAPFGYFEDW in-frame - acctcggaatttctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5009 JY8QFUQ01AZHXC productive (see comment) Homsap IGHV3-7*01 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELEDYSDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggattcacatttagtaactactggatgagctgggtccgccaggCctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattggaggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5010 JY8QFUQ01C7E4L productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5011 JY8QFUQ01BZ4LZ No results 5012 JY8QFUQ01DN5JL No results 5013 JY8QFUQ01CPO52 No results 5014 JY8QFUQ01AC3GH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 5015 JY8QFUQ01DSYWV unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta 5016 JY8QFUQ01DGMHL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5017 JY8QFUQ01CMBZ5 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 115 54.2 71/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons gtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 5018 JY8QFUQ01AXXAF No results 5019 JY8QFUQ01BYHVS No results 5020 JY8QFUQ01CDBFA No results 5021 JY8QFUQ01A4LYQ productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5022 JY8QFUQ01BZ77K productive Homsap IGHV3-9*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatctttgatgattttgccatgcactgggtccggcatgctccagggaggggcctggagtgggtctcaagtatcaactggaatggtgacgtcaaagcctatgcggactccgtgaagggccgattcaccgtctccagggacaacgtccaaaactcactgtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5023 JY8QFUQ01BRHVU productive (see comment) Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 542 70.87 163/230 nt 70.0 161/230 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 15 8.7.15 [7.17.37.11] CARERDKSAAGGDFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (70,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 227 in the user submitted sequence), (cause frameshift) gtctccagtgacattattaatagcgaaggtttcggtcgtttctactggaactgggtccGggcagatcgacgggcaggggctggagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccatccttcgggacccggataagtttgtcgttagactcgtccaagaggcagttttccctgaagttacagtctgtgaccgccgcagacacggccgtatattttgtgcgagggagcgtgacaagtcggcggcgggcggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5024 JY8QFUQ01ARLTJ No results 5025 JY8QFUQ01CAQM5 unproductive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [0.17.38.11] CARVIRTNWL#PW out-of-frame - tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatgataatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacggccgtatattattgtgcgcgagtaattcgaaccaactggctcgaccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5026 JY8QFUQ01BM7LQ productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.16.38.11] CATRSRSPANW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcagttttagtacctattggatgagctgggtccgccaggctccagggaagggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaattcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5027 JY8QFUQ01C8ERB No results 5028 JY8QFUQ01AN8M3 No results 5029 JY8QFUQ01AGRBK productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.16.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaagggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5030 JY8QFUQ01B8Q6L No results 5031 JY8QFUQ01ABL5K productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYYFDSW in-frame + ctctggattcaccttcagtatttattctatgcattgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacggctgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagcccaaggtcttcccgctgacgcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5032 JY8QFUQ01DVS60 No results 5033 JY8QFUQ01ACBC6 No results 5034 JY8QFUQ01BVBOA productive Homsap IGHV3-66*02 F 813 86.92 186/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-10*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARVRFGPSYLDVFDIW in-frame + ctctggattcaccgtcaatagttatcacatgagttgggttcgccaggctccagggaaggggccggagtgggtctcaattatttatccggatggtgacgcattctacgcagactccgtgaagggccgattcaccttctccagagacatttccaagaacacggtgtatctccaaattaacagagtgacaactgaggacacggctatgtactactgtgcgagagtccggttcgggccaagttatctggatgtctttgacatctggggccaagggacattggccaccgtctcttcagcatccccggaccagcccaaggtcttcccgctgagcctctgcagcaccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 5035 JY8QFUQ01BWW54 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 134 63.29 50/79 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5036 JY8QFUQ01A0Y9N No results 5037 JY8QFUQ01AZG3J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5038 JY8QFUQ01DS4YW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 491 84.56 115/136 nt 83.09 113/136 nt 8 8 X 8.8.X [1.16.11.X] null + No rearrangement found Low V-REGION identity (84,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 5039 JY8QFUQ01BOVSG unproductive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.3 192/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgGaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctgggccaaggaccacggtcaccgtctcctcagcatcccggaccagcccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5040 JY8QFUQ01A5AND productive Homsap IGHV3-30*15 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame + ctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5041 JY8QFUQ01BZNR8 No results 5042 JY8QFUQ01DOOBW productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASVVTINDNGDYTWAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcaataattacttctggacctggatccgccagTcccccagggaaggggccggagtggattggggaaatcaatcatagtggtagcaccaactacaatccgtccctcaagagtcgagtcaccatctcaatagacacgtccaagatccagttctccctgcagctgagctctgtgaccgccgcggacacggctgtctattactgtgccagtgtagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5043 JY8QFUQ01CCKWB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5044 JY8QFUQ01AUYN2 No results 5045 JY8QFUQ01DJ448 No results 5046 JY8QFUQ01AJHY7 No results 5047 JY8QFUQ01CLTWE unknown (see comment) Homsap IGHV3-7*02 F 103 58.75 47/80 nt 8 1 X 8.1.X [0.17.X.X] null + No rearrangement found ctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5048 JY8QFUQ01DFDPJ No results 5049 JY8QFUQ01A97QT productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 5050 JY8QFUQ01A09MY No results 5051 JY8QFUQ01DIMK5 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 5052 JY8QFUQ01AP6HU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5053 JY8QFUQ01DHFHJ No results 5054 JY8QFUQ01DFNDX productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctacctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5055 JY8QFUQ01B2EJ0 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 5056 JY8QFUQ01AFMEW No results 5057 JY8QFUQ01CM2M0 No results 5058 JY8QFUQ01DEH2Y productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD2-8*02 F 2 8 8 18 8.8.18 [1.17.38.11] CARDLDYSNGGVSYDALDVW in-frame + ctctggatccacctttagtaattattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacatagagaaagacggaagtgtggagaactatttggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtatctgcaaatgaacggcctgagagccgaagatacggctgtctattactgtgcgagagatttggattatagtaatggtggtgtctcgtacgatgctcttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5059 JY8QFUQ01DAH5C No results 5060 JY8QFUQ01CFD78 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKVSGNSRTYWYLDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); ggttctggatacaactttcccagatattggatcgcctCgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5061 JY8QFUQ01BHQK6 productive Homsap IGHV3-9*01 F (see comment) 793 84.93 186/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [2.17.38.11] CGRIAKPGLGALDLW in-frame - Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5062 JY8QFUQ01CRABK productive Homsap IGHV3-21*04 F (see comment) 626 76.61 167/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame - Low V-REGION identity (76,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5063 JY8QFUQ01DGGN2 No results 5064 JY8QFUQ01DVMYE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaattacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5065 JY8QFUQ01A2N5A No results 5066 JY8QFUQ01A77BB unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 X 8.7.X [1.17.38.11] CARPHI*QRP#DAFDTW out-of-frame + stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggccccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5067 JY8QFUQ01DAEUC No results 5068 JY8QFUQ01BGJYF productive Homsap IGHV3-30*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca 5069 JY8QFUQ01BVQBH No results 5070 JY8QFUQ01C74JE No results 5071 JY8QFUQ01ANKSU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ccggattcagtttcagtacttaGtaacatgaattgggtccgccaggctccagggaaTggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5072 JY8QFUQ01AFDCM productive Homsap IGHV4-39*03 F 920 90.91 200/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] CTREGPYYYGMDVW in-frame + tctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 5073 JY8QFUQ01DLSNF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5074 JY8QFUQ01CYNKU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctggattcaccttcagtacatactggatgcactgggtccaccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5075 JY8QFUQ01C6DDZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDMGGDYYIFHYW in-frame + ttctggattctcctttagcaactatgccctggcctgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5076 JY8QFUQ01DJO6B productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVRGSSGRFDSW in-frame + ctctggattcaccttcagaaaatatgctatgcactgggtccgccaggctccaggcaaggggctggaatgggtggcgattatatcctatgatggaagaagtccatactacgcagactccgtgaggggccgattcaccatctccagagacaattccaggagtactctggatctgcagatgaacagcctgagacctgaggacacggctgtatattcctgtgtgagaggaagcagtggccgctttgactcctggggcccgggaacgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 5077 JY8QFUQ01C6DIT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5078 JY8QFUQ01BUZ3T No results 5079 JY8QFUQ01AR2LH No results 5080 JY8QFUQ01DP8YH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtGgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5081 JY8QFUQ01BUXBZ No results 5082 JY8QFUQ01DU88I unknown (see comment) Homsap IGHV5-51*05 F 149 56.62 77/136 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found gttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5083 JY8QFUQ01CQ0LJ productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGRRDNTGYYWYYFESW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'G' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); cagagactcctttatcagctatgGttttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtcccgatgtctgccacagcaaattatgcacagaagttccagggcagagtcacaattGaccgcggacggatccacgagcacagcctacatggaattgagcagcctgagatctgaggacacggccatgtattactgtgcgagagggagacgggataatactggttattattggtactactttgaatcctggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 5084 JY8QFUQ01C8GBT No results 5085 JY8QFUQ01CPIJA productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5086 JY8QFUQ01B37M4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.16.38.11] CVSDLAGQKGSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5087 JY8QFUQ01AXJEC unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F (see comment) 204 78.79 52/66 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (78,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccccc 5088 JY8QFUQ01CD1G0 No results 5089 JY8QFUQ01BTQNU No results 5090 JY8QFUQ01AZ9YP No results 5091 JY8QFUQ01AKGXY unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 5092 JY8QFUQ01A26C2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5093 JY8QFUQ01A2UDI No results 5094 JY8QFUQ01CB6I7 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 687 80.37 172/214 nt 79.91 171/214 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD1-7*01 F 1 8 7 X 8.7.X [1.17.38.11] CARLDGHFDL## out-of-frame + Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 77 of V-REGION: 'GAA' (3 nucleotides at position 131 to 133 in the user submitted sequence), (do not cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcgggcttGAAtcgatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5095 JY8QFUQ01CS6PE productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctGgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5096 JY8QFUQ01BBZNR No results 5097 JY8QFUQ01BC565 No results 5098 JY8QFUQ01BADKE No results 5099 JY8QFUQ01APK97 productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5100 JY8QFUQ01CTUEZ productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccgagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5101 JY8QFUQ01APG97 No results 5102 JY8QFUQ01CMK2H productive Homsap IGHV3-48*02 F 971 94.88 204/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 1 8 8 19 8.8.19 [0.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame - ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgtttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5103 JY8QFUQ01CZGGI No results 5104 JY8QFUQ01DIATI productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5105 JY8QFUQ01DDI7L No results 5106 JY8QFUQ01BS2WD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtactaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5107 JY8QFUQ01A6LFT productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5108 JY8QFUQ01CIW5U No results 5109 JY8QFUQ01AN1WA No results 5110 JY8QFUQ01C8HAX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGVRGVGAYYIYYF#DLW out-of-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttcgacttatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5111 JY8QFUQ01DTGQA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 714 81.78 175/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (81,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcgcctcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttct 5112 JY8QFUQ01A6WP2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 854 90.78 187/206 nt 90.29 186/206 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5113 JY8QFUQ01BGM6K No results 5114 JY8QFUQ01CWSIN No results 5115 JY8QFUQ01AHJ9B productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5116 JY8QFUQ01BANEM No results 5117 JY8QFUQ01DPKNZ productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 393 91.49 86/94 nt 90.43 85/94 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5118 JY8QFUQ01BQOPQ productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.16.38.11] CVSSPYFYDSNGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaagggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaacgatggaacgtggtcgtcgcatgcctggtccagggcttctt 5119 JY8QFUQ01ASOJD No results 5120 JY8QFUQ01DRI4G No results 5121 JY8QFUQ01CKARI productive (see comment) Homsap IGHV3-30*13 F (see comment) 228 77.22 61/79 nt 75.95 60/79 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 X X 14 X.X.14 [X.X.26.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (77,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 87 of V-REGION: 12 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactatcacatgtactggatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5122 JY8QFUQ01CNHKN No results 5123 JY8QFUQ01BPO99 No results 5124 JY8QFUQ01BOPDW No results 5125 JY8QFUQ01CBTGU No results 5126 JY8QFUQ01CXUGN unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5127 JY8QFUQ01A4D0Z productive (see comment) Homsap IGHV1-3*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagtacctatactatgaattgggtgcgccaggGcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5128 JY8QFUQ01DFW5N productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5129 JY8QFUQ01C7X1A unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARGMATAES## out-of-frame + ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagcccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5130 JY8QFUQ01AS7JA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gtctggattcacAgtttagaagctaGttccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5131 JY8QFUQ01CUCMD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 828 87.1 189/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tgtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccatggcttcttccccca 5132 JY8QFUQ01CIAB5 No results 5133 JY8QFUQ01AT3R5 unproductive Homsap IGHV3-33*03 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5134 JY8QFUQ01C7PBB No results 5135 JY8QFUQ01ABIUK productive (see comment) Homsap IGHV3-13*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.37.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 192 in the user submitted sequence), (cause frameshift) cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccgggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5136 JY8QFUQ01A0WZB productive Homsap IGHV3-66*02 F (see comment) 759 84.11 180/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame + Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5137 JY8QFUQ01CO6CF unproductive (see comment) Homsap IGHV3-7*01 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.16.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) gcctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5138 JY8QFUQ01BZQY5 productive Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F (see comment) 388 78.29 101/129 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-8*01 F 2 X 5 17 X.5.17 [X.X.38.11] CVRDVSLYSNDGYDAFDIW in-frame + Low V-REGION identity (78,29% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcattttagtaacttttggatgagttggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagagacgtctccctttatagtaatgatggatatgatgcttttgatatttggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccca 5139 JY8QFUQ01DDAQ6 productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtgcgtggaactcag 5140 JY8QFUQ01DGCAX unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 93.38 141/151 nt 8 8 X 8.8.X [1.17.15.X] null - No rearrangement found in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 125 in the user submitted sequence), (cause frameshift) ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaaggccgattcaccatctccagagacaatg 5141 JY8QFUQ01AT892 No results 5142 JY8QFUQ01BQGYG unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 910 90.87 199/219 nt Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [2.17.38.11] CVRSEYSSSNWFDP# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgaccctggggccagggaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5143 JY8QFUQ01C4PMS No results 5144 JY8QFUQ01DEWTJ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDSDSSGYARYDSMDV## out-of-frame + in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgGggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaatgggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactca 5145 JY8QFUQ01AMARQ productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.37.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtAGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgagggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5146 JY8QFUQ01C8QWZ productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccc 5147 JY8QFUQ01AM7DF No results 5148 JY8QFUQ01AH10K productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccAaagctccggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5149 JY8QFUQ01BA59S unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1061 99.53 214/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctgatggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5150 JY8QFUQ01AIWSZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 508 70.83 153/216 nt Homsap IGHJ1*01 F, or Homsap IGHJ5*02 F (see comment) 17 71.43 5/7 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (70,83% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 5151 JY8QFUQ01ALLUG No results 5152 JY8QFUQ01APGUQ No results 5153 JY8QFUQ01BLBYX productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - tgttcggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5154 JY8QFUQ01DSN0F unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5155 JY8QFUQ01AWLZU No results 5156 JY8QFUQ01CFKI3 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacaGccccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgc 5157 JY8QFUQ01A3G7V unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 788 92.86 169/182 nt 92.31 168/182 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD3-16*02 F 1 6 8 X 6.8.X [1.6.38.11] CARDGPPLV**FSWGSYRHPT#WFDPW out-of-frame + stop codons in CDR1-IMGT, from codon 37 of V-REGION: 35 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtggttaacctggagtgggtctcatccattactagtaatactacttacatatacaacacagactcagtggagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagaaccgaggacacggctgtgtattaatgtgcgagagatggacctccgctggtatgatgattttcttgggggagttatcgtcatcctacgtctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 5158 JY8QFUQ01BKSL7 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 703 80.37 176/219 nt 79.0 173/219 nt 8 8 X 8.8.X [2.16.37.X] null - No rearrangement found Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 126 in the user submitted sequence), (cause frameshift) cagcctctggatccagtttcagtggAttttggcgtgaactgggtccgccaggctccagggaagggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgagggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5159 JY8QFUQ01B2OZ4 No results 5160 JY8QFUQ01C1NY7 No results 5161 JY8QFUQ01DI6EW productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [1.17.38.11] CARGGGGKSIPLDNW in-frame + gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5162 JY8QFUQ01AE4ZJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 130 67.74 42/62 nt Homsap IGHD1-1*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKMKGLYYYDYGMDVW in-frame + ttctggactcaccttcagcagctttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagctatgagtggtagtggtagtagcacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagtgccgacgacacggccgcatattactgtgcgaaaatgaaaggactttactactacgactacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5163 JY8QFUQ01DNO4C No results 5164 JY8QFUQ01CSZL8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctcaggactcatgtttagcagctatgccatgacctgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 5165 JY8QFUQ01DIK46 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5166 JY8QFUQ01C4LUX No results 5167 JY8QFUQ01B6F5W productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5168 JY8QFUQ01BP9GL productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame + ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5169 JY8QFUQ01BMSTT productive (see comment) Homsap IGHV3-9*01 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatcCtttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5170 JY8QFUQ01C7VF4 productive (see comment) Homsap IGHV3-30*01 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttaCtttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5171 JY8QFUQ01CLEUK unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 360 63.77 132/207 nt 8 8 X 8.8.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (63,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtcaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5172 JY8QFUQ01CFBGF No results 5173 JY8QFUQ01AF4W2 No results 5174 JY8QFUQ01A882H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CARDLPAMGKYYYGMDVW in-frame + ctctggatttatgctcaggacttatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagaaatacagattacacatattacgcagactcagtgaggggccgattcaccatctccagagacaacgccgaaaactcactatttttgcaaatgagcagtctgagagccgaggacacggctctctatttctgtgcgagagatttgccggctatgggaaagtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5175 JY8QFUQ01BK44J unproductive (see comment) Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKDMVAGQGLLSR#FDHW out-of-frame + stop codons Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggttttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5176 JY8QFUQ01AEWPW productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctcaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5177 JY8QFUQ01CMEYE No results 5178 JY8QFUQ01BN31F productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccctca 5179 JY8QFUQ01AT7IJ No results 5180 JY8QFUQ01ARI0Z productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 5181 JY8QFUQ01C61KK productive Homsap IGHV3-11*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARARGVIPSFW in-frame - cctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaagggggctgagtgggtttcatacattagtagtagtggtggttccgtatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagacctcactgtatctgcaaatgaacaatctgagagccgaggacacggccgtgtattactgtgcgagagcccggggagtaatcccttcattctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 5182 JY8QFUQ01BN5MV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cgtctggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 5183 JY8QFUQ01BCXG0 No results 5184 JY8QFUQ01DWPP9 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1019 95.93 212/221 nt 95.48 211/221 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [2.17.38.11] CVRSEYSSSNWF#PW out-of-frame - in FR3-IMGT at codon 77 of V-REGION: 'G' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcGaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgaccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5185 JY8QFUQ01B7KB8 No results 5186 JY8QFUQ01DD8NN productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggCcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttcccccatggcacccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag 5187 JY8QFUQ01AE0ZW productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5188 JY8QFUQ01B3WH5 No results 5189 JY8QFUQ01AHVRK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5190 JY8QFUQ01B0UUI unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 881 90.23 194/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [0.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - stop codons tctgattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5191 JY8QFUQ01CQYHB unknown (see comment) Homsap IGHV4-59*02 F 899 90.7 195/215 nt 89.77 193/215 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 108 to 119 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5192 JY8QFUQ01DHH0D productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5193 JY8QFUQ01CXD60 unknown (see comment) Homsap IGHV3-74*03 F 160 54.05 100/185 nt 8 8 X 8.8.X [1.17.27.X] null - No rearrangement found ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtcaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5194 JY8QFUQ01CIAYO No results 5195 JY8QFUQ01ACBYC No results 5196 JY8QFUQ01DVGYW No results 5197 JY8QFUQ01C6Z6P unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F 142 82.93 34/41 nt 8 X X 8.X.X [0.5.X.X] null + No rearrangement found tggatacacattcaccggccacttcgtccactggctgcgac 5198 JY8QFUQ01AJTH3 productive Homsap IGHV4-39*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 10 7 12 10.7.12 [1.17.38.11] CASVTTVSMRMKYW in-frame + ctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5199 JY8QFUQ01CLIPB No results 5200 JY8QFUQ01A2Y4W No results 5201 JY8QFUQ01B8PVL No results 5202 JY8QFUQ01DLE29 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5203 JY8QFUQ01C9MW1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 862 89.67 191/213 nt 89.2 190/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 8 10 7.8.10 [0.17.38.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tggattcacttcagtaacgcctggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5204 JY8QFUQ01DT69E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 193 93.18 41/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found tctggattcaccttcagcaagtatgccatgagctgggtccgcca 5205 JY8QFUQ01A4JI5 productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 9 8.8.9 [1.17.38.11] CAWGPNGADYW in-frame + ctctggattcaccttcggtaactcaaccatgaactgggtccgccaggctccagggaaggggctggaatggctgtcatatcttagtagtggtggtgatgtcaaatactacgcaggctctctgaagggccgattcaccatctccagagacagtgccaggaactcactgtatctgcaaatgaacagcctgacagacgaggacacggccgtatattactgtgcatgggggcccaacggcgccgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5206 JY8QFUQ01BEWRY No results 5207 JY8QFUQ01CY8X5 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 933 93.84 198/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 7 8 X 7.8.X [X.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons attcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5208 JY8QFUQ01DD5MD No results 5209 JY8QFUQ01C29L1 unproductive Homsap IGHV4-4*07 F, or Homsap IGHV4-59*08 F or Homsap IGHV4-59*10 F or Homsap IGHV4-61*02 F or Homsap IGHV4-61*06 ORF (see comment) 397 84.68 94/111 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 X X X X.X.X [X.X.37.11] CASTGYTSAPSEWMDV# out-of-frame - Low V-REGION identity (84,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tggtggttccatcaccagtgtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaatctgaactctgtgaccgccgctgacacggccgtgtattactgtgcgagtaccggatataccagtgccccaagcgagtggatggacgtctgggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5210 JY8QFUQ01AZPKZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 7 11 8.7.11 [1.16.38.11] CTRVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) tctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaagggctggaatgggtcggtggtgttaattggaatggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5211 JY8QFUQ01CXI17 productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5212 JY8QFUQ01DTIG3 No results 5213 JY8QFUQ01CZ7HA productive Homsap IGHV4-4*07 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLPTVTTGALDIW in-frame + ctctggtggctccttcagtaattaccactggagctggatccggaagcccgccgggaaggaactggagtggattgggcgtatccatcacagtgggctcaccaactccaacccctccctcaagaatcgagtcgtcgtgtcagtggatacgtccaagaatcagttgtccctggagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcctacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggactgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 5214 JY8QFUQ01A3VGZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 905 90.83 198/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) gcctcctggattcaccCtttggttattatggcatgactggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5215 JY8QFUQ01A453G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 879 89.09 196/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [2.17.38.11] CVREGAATGSFYYW in-frame - aacctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5216 JY8QFUQ01B4TSK productive Homsap IGHV3-9*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CAKGETVVTPGDYW in-frame + ctctggattcacctttgatgattgtgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggcagcatcggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttacaaatgaatagtctgagacctgaggacacggccttatattactgtgcaaaaggagagacagtggtaactccaggagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5217 JY8QFUQ01AMCYK unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 756 86.93 173/199 nt 86.43 172/199 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-13*01 F 2 8 1 12 8.1.12 [1.17.38.11] CAKAPGTATSEDLW in-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 19 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) cctctggattcagttttcgcagctgtggcatgacctgggtccgccaggctccagggaaggggctgcagtgggtctcaccttttagtgctacgcagactccgtgaagggccggttcagcattttcagagacaactcggagaacacactctatctgcaattgaacagcctgagagccgaggacacggccgtttgttattgtgcgaaagcccccgggacagcaacatctgaggacctctggggccagggaacccaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5218 JY8QFUQ01CKYMP No results 5219 JY8QFUQ01DPTIU productive Homsap IGHV4-61*02 F 929 91.4 202/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARATLSDVDTPLGFDYW in-frame + tctctggtgtctcaatcacgagtggaagtcactactggaattggattcggcagcccgccgggaagggaccggagtggattgggcgtttctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccgtatcagcagacacgtccaagaaccggctctccctgaagctgagatctttgaccgccgcagacacggctgtttattactgtgcgagagcaaccttgtctgacgtggatacacctttgggctttgactactggggccagggaatcttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5220 JY8QFUQ01B8UCZ unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt 8 7 X 8.7.X [4.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccccttggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5221 JY8QFUQ01C84NL unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 106 53.44 70/131 nt 8 8 X 8.8.X [0.17.10.X] null - No rearrangement found stop codons tggattcaccttcagtagatactggatgcactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5222 JY8QFUQ01B7E5F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 5223 JY8QFUQ01CD6QH No results 5224 JY8QFUQ01BM70U productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5225 JY8QFUQ01DL6BO unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F 131 51.44 107/208 nt 8 8 X 8.8.X [2.17.34.X] null - No rearrangement found gcctctggattcaactttgaagattatgccatgtactgggtccgacaacctccagggaagggcctggagtgggtctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5226 JY8QFUQ01CO8HU unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctgattcagcttcagtacctaGtaacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5227 JY8QFUQ01AK3I6 No results 5228 JY8QFUQ01A3SDR No results 5229 JY8QFUQ01BKSUX productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1034 98.14 211/215 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 5230 JY8QFUQ01DS4J6 productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5231 JY8QFUQ01C0KDB unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 121 82.86 29/35 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found gtctggatttaccttcagtaagttctggatgcatt 5232 JY8QFUQ01BJ3SK No results 5233 JY8QFUQ01CI4KV productive Homsap IGHV1-8*01 F 844 88.26 188/213 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [X.17.38.11] CARVGGTHYHYGVDVW in-frame - ggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5234 JY8QFUQ01DJS23 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 865 88.58 194/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ggcctcctggattcaccCTttgggttattatggcatggactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5235 JY8QFUQ01CCRES No results 5236 JY8QFUQ01A05FU No results 5237 JY8QFUQ01DPTKE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5238 JY8QFUQ01A7O8D No results 5239 JY8QFUQ01BH9L3 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKITPL*QEWSII#DYW out-of-frame - stop codons in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctgggtcactttttggccactataccatgagctgggtccgccaggctccagggaAaggggctggagtgggtctcagctattggtaatagtggtgatattacatactacgcagactccgcgaggggccggttcaccatctccagagacaattcccagaacacactgtatctgcaagtgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaataacccccctatgacaggagtggtccattataccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5240 JY8QFUQ01AEEE7 unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 733 82.41 178/216 nt 81.94 177/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.17.38.11] CARDLGWKLR*V#YFDYW out-of-frame - stop codons Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); gtccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtCgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagatttggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5241 JY8QFUQ01CTKX9 productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5242 JY8QFUQ01ATVCJ No results 5243 JY8QFUQ01DVXY4 unproductive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSL*N#DYW out-of-frame - stop codons ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagtttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcaccctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5244 JY8QFUQ01A4KHC No results 5245 JY8QFUQ01BASL4 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CATLRGVLS#Y out-of-frame + ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggtactttcgactactgggccgggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggccaccctcctccaagagcacctctggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactcag 5246 JY8QFUQ01BB93A No results 5247 JY8QFUQ01ALUXL No results 5248 JY8QFUQ01AW0KM productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5249 JY8QFUQ01A5HXY productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 826 87.79 187/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame - tctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5250 JY8QFUQ01CVIUK No results 5251 JY8QFUQ01BEK3T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 5252 JY8QFUQ01BC75P productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 714 81.78 175/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (81,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcctcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5253 JY8QFUQ01ANKJV productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-1*01 F 2 8 8 9 8.8.9 [2.17.38.11] CARRQLALAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); catctgggatacacctttatcacctactggatcgcctgggtgcgccaaatgcccgggaAaaggcctggagttgatgggagtcatctatcctggtgactctgagaccagatacagcccgtccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5254 JY8QFUQ01AT2XH productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5255 JY8QFUQ01A7BIA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 5256 JY8QFUQ01DQQ3Y productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5257 JY8QFUQ01CFREB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 876 96.77 180/186 nt 8 8 X 8.8.X [1.17.27.X] null - No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcca 5258 JY8QFUQ01DQGXH productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 857 89.62 190/212 nt 89.15 189/212 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 13 7.8.13 [X.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); ttcaccctttgggttattatggcatgagctggatccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5259 JY8QFUQ01BIH2H productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5260 JY8QFUQ01A72B2 No results 5261 JY8QFUQ01AK8LP productive (see comment) Homsap IGHV4-61*02 F (see comment) 731 81.45 180/221 nt 81.0 179/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 9 6 16 9.6.16 [3.17.38.11] CAIERSRSIGGDGQFDFW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01AK8LP ; 10 AA in Homsap_IGHV4-61*02), and low V-REGION identity (81,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 105 in the user submitted sequence), (do not cause frameshift) tctctgggtgggcccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5262 JY8QFUQ01BKK6X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5263 JY8QFUQ01BIGLC productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccaggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 5264 JY8QFUQ01BGPQC No results 5265 JY8QFUQ01BLMPU productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtctctggtattaattggaatggtggtaagacaggttatggagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5266 JY8QFUQ01B35FR unproductive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDDDFWEW*T#FDPW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift) ctctggattcagtcttaataactactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagagacgacgatttttgggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5267 JY8QFUQ01BCSTY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 779 83.94 183/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5268 JY8QFUQ01CRUKP No results 5269 JY8QFUQ01CCLMC No results 5270 JY8QFUQ01CLS91 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 130 55.22 74/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5271 JY8QFUQ01B2X20 No results 5272 JY8QFUQ01ACF7K No results 5273 JY8QFUQ01A5JTB No results 5274 JY8QFUQ01A82RF productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5275 JY8QFUQ01AZE1O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5276 JY8QFUQ01CS0AM No results 5277 JY8QFUQ01B3CD7 unknown (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggcctggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctcAcctgaagctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaagcgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5278 JY8QFUQ01C2CGR No results 5279 JY8QFUQ01BKXOJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 796 85.65 185/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDSW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tatggattcaacttcattggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaaaagaacactgtttctccaaatggacaacctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5280 JY8QFUQ01C6JUQ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 6 10 9.6.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatgtgggggcaccaattacaAacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5281 JY8QFUQ01DA6VQ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 5282 JY8QFUQ01CGLQV No results 5283 JY8QFUQ01A5BO8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5284 JY8QFUQ01B4DTC No results 5285 JY8QFUQ01B5D43 unknown (see comment) Homsap IGHV3-21*04 F (see comment) 720 81.11 176/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 5286 JY8QFUQ01C3P0G No results 5287 JY8QFUQ01AL4I4 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARAYSGPG#YYFDYW out-of-frame + ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccaggctcttccccc 5288 JY8QFUQ01C67BE productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame + tctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagcctcaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5289 JY8QFUQ01CWHH2 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgGacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5290 JY8QFUQ01CMRYI No results 5291 JY8QFUQ01AKS4K unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 760 83.8 181/216 nt 82.87 179/216 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [2.17.38.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); gtctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtGcccttggcagtcgagtctccatatcactggacacgtcCcaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5292 JY8QFUQ01BXIJY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-1*01 F 2 10 7 8 10.7.8 [1.17.38.11] CATVDRLTYW in-frame + tctctggtgtctccatgagcagtcttacttactactggggctggattcgccagccccccgggaagggcctggagtggattgggactctcttttatagtgggagcacctactacaatccgtccctcaggagtcgagtcaccatatccgctgactcgtccaagaaccagttctccctgaacctaaggtctgtgaccgccgcagacacggctgtctatttctgtgcgacggtggatcgactgacctactggggccggggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 5293 JY8QFUQ01C0ACH No results 5294 JY8QFUQ01C79UA No results 5295 JY8QFUQ01A5QCW productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - agtctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5296 JY8QFUQ01DMD7B productive Homsap IGHV3-7*01 F (see comment) 733 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5297 JY8QFUQ01BD5WV No results 5298 JY8QFUQ01A9VFZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5299 JY8QFUQ01AZX3F productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARVGYGYRGIYFFGAYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttggagcctactggggccagggaaccctggtcacccgtgcctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5300 JY8QFUQ01AEE1F unknown (see comment) Homsap IGHV3-23*05 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5301 JY8QFUQ01AXVYW No results 5302 JY8QFUQ01CY70Q unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 5303 JY8QFUQ01C8JUC No results 5304 JY8QFUQ01DTA7K productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 5305 JY8QFUQ01DVBU0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 5306 JY8QFUQ01A9MNS productive (see comment) Homsap IGHV3-66*02 F (see comment) 760 83.8 181/216 nt 83.33 180/216 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [2.17.38.11] CARHLMVYALDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gtctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggGggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5307 JY8QFUQ01AD07C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5308 JY8QFUQ01BRGBS productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5309 JY8QFUQ01CUJMD productive Homsap IGHV3-48*02 F 1026 97.24 211/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD1-1*01 F 2 8 8 20 8.8.20 [1.17.38.11] CASGERKDYEVRRDYYHGMDVW in-frame + ctctggactcaccttcagcagctatagtatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 5310 JY8QFUQ01AE4G5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 5311 JY8QFUQ01ANPDJ productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5312 JY8QFUQ01DMRYE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaagggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 5313 JY8QFUQ01CSZHP unknown (see comment) Homsap IGHV3-74*03 F, or Homsap IGHV3-NL1*01 F 141 57.5 69/120 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgatagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 5314 JY8QFUQ01A1GZY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) agcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5315 JY8QFUQ01ASYTM unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 924 93.36 197/211 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 7 8 X 7.8.X [X.17.38.11] CANACPPV*LE#YFYYYGMDVW out-of-frame - stop codons attcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacatatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctgcccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5316 JY8QFUQ01CZQGS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5317 JY8QFUQ01DN3JU unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5318 JY8QFUQ01CL6OG productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 803 86.38 184/213 nt 85.92 183/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.37.11] CARRSTSGDKFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tggagggaacttcaacaattatggtttcagctgggtgcgacaggcccctggacaaggccttgagtggatgggagaaatcatcccattttttggaacatcaaaatanacacagaattccagggcagactctccattaccgcggacgaatccacgagcacagcctttatggacttgagtggcctgagatctgaggacacggccgtctattattgtgcgagaaggtctactagtggggataaatttgacttctggggccagggaagccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5319 JY8QFUQ01AOC88 No results 5320 JY8QFUQ01DSF5L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5321 JY8QFUQ01CBJNI No results 5322 JY8QFUQ01DNDQ8 No results 5323 JY8QFUQ01AXQMT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 429 76.87 113/147 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (76,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca 5324 JY8QFUQ01CZY00 No results 5325 JY8QFUQ01A2B2A productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5326 JY8QFUQ01CFHFO No results 5327 JY8QFUQ01BE70Q No results 5328 JY8QFUQ01AN3ES productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgctggtcccagggcttcttccccca 5329 JY8QFUQ01B66LL unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKVRAPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5330 JY8QFUQ01CYN05 No results 5331 JY8QFUQ01A7AKD unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-7*01 F 2 8 8 X 8.8.X [1.17.38.11] CATGAGNWNY#FNYW out-of-frame + ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtggtttttatatatactacgcggattcagtgaagggccgagtcaccatctccagagacaacgccaagaattcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacattttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5332 JY8QFUQ01DOSRH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 5333 JY8QFUQ01B82UI productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 5334 JY8QFUQ01B3U51 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccctgaccagccccaaggtcttcccgctgagctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5335 JY8QFUQ01B7J6Z unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 5336 JY8QFUQ01B731P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 803 86.79 184/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [0.17.38.11] CARGRTVVTVIDYIDYW in-frame + ctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5337 JY8QFUQ01DKJWG productive (see comment) Homsap IGHV3-21*04 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 7 8 10 7.8.10 [1.17.37.11] CAREVSDALDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 93 of V-REGION: 1 nucleotides (from position 183 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaattctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5338 JY8QFUQ01CQP3F productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5339 JY8QFUQ01CQW8C productive Homsap IGHV4-61*02 F 988 94.14 209/222 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARGSGSGSYSNLW in-frame - ctctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5340 JY8QFUQ01BXULP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + ctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5341 JY8QFUQ01AIJPD No results 5342 JY8QFUQ01BZC5P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccaggtgacggtgtcgtggaactc 5343 JY8QFUQ01CV8A6 No results 5344 JY8QFUQ01DFT66 productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 749 82.27 181/220 nt 81.82 180/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [2.17.37.11] CARVWVAGSRDENFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) gtctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgtttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5345 JY8QFUQ01CDRM8 No results 5346 JY8QFUQ01DI90L productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPYNGGGYGAFDIW in-frame + ctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccatcataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccca 5347 JY8QFUQ01CQ3ZM productive Homsap IGHV3-48*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame + ctctggattcatctttgatgattttggcatgaattgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccggaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5348 JY8QFUQ01ASYBM No results 5349 JY8QFUQ01A7RIF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5350 JY8QFUQ01CPVXS unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 719 81.86 176/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (81,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5351 JY8QFUQ01A0364 No results 5352 JY8QFUQ01BZUN4 unknown (see comment) Homsap IGHV3-30*07 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. gcctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5353 JY8QFUQ01A8AJT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CMNEFGYCSGGG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'T' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); gctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatTttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5354 JY8QFUQ01DKKPO No results 5355 JY8QFUQ01A4MZ9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5356 JY8QFUQ01DOZMM No results 5357 JY8QFUQ01C2K80 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame - tctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5358 JY8QFUQ01APMVK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5359 JY8QFUQ01BGOQC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 139 88.57 31/35 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctacattcgcctttagcaactatgccatgagctg 5360 JY8QFUQ01BT6UT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 455 87.29 103/118 nt 8 8 X 8.8.X [1.17.4.X] null - No rearrangement found cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcttccccca 5361 JY8QFUQ01C7XJ3 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F 570 92.42 122/132 nt 91.67 121/132 nt 10 7 X 10.7.X [1.2.23.X] null + No rearrangement found in FR2-IMGT, from codon 39 of V-REGION: 44 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) ctctagtgactccatcagcagtactaattactactgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctga 5362 JY8QFUQ01AZLXE No results 5363 JY8QFUQ01ATV1R productive (see comment) Homsap IGHV3-7*02 F 907 91.59 196/214 nt 90.19 193/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*02 F 3 8 8 13 8.8.13 [1.16.38.11] CARLSGRIRNAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggatttacctttagtagtaactggagacgtgggtccggccngctccagggaagggctggagtgggtggccacataaagatggatggaagtgagcattactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctggaaatgcacagcctgagagccgaggacacggctctgtattactgtgcgagactctcgggacggatccgcaatgctttcgatctctggggccaagggacaatggtcactgtctctttagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5364 JY8QFUQ01AB8J9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5365 JY8QFUQ01BOHQR No results 5366 JY8QFUQ01CXUN7 No results 5367 JY8QFUQ01CUGZN unknown (see comment) Homsap IGHV5-51*05 F 149 56.62 77/136 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found gttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5368 JY8QFUQ01BVN36 No results 5369 JY8QFUQ01A9LJF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 589 77.66 153/197 nt 77.16 152/197 nt 8 8 X 8.8.X [1.17.31.X] null - No rearrangement found Low V-REGION identity (77,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); ctccgaattcatccttgacagttatgccatgGagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5370 JY8QFUQ01BA5EZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) gcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccttgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5371 JY8QFUQ01CBM5L No results 5372 JY8QFUQ01BC6EZ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 614 76.42 162/212 nt 7 8 X 7.8.X [X.17.38.X] null - No rearrangement found Low V-REGION identity (76,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5373 JY8QFUQ01A9MMF productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 5374 JY8QFUQ01AYSO6 productive Homsap IGHV4-61*02 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame - tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatgtcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5375 JY8QFUQ01AEMXL productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 5376 JY8QFUQ01B6ATU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 993 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcgaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5377 JY8QFUQ01ADXSU unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 5378 JY8QFUQ01CYQNH No results 5379 JY8QFUQ01A3HNF No results 5380 JY8QFUQ01AOELI No results 5381 JY8QFUQ01DAVHO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDPGNYWGYYYDS## out-of-frame + ctctggattcacctttagcagttatgccatgagctgggtccgccagactccagggaaggggctggagtggatctcagaaattactggtgatggcgataacatatactacgcagactccgtgaagggccgtttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatccggggaactattgggggtactactatgactcttgggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5382 JY8QFUQ01AWYM5 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5383 JY8QFUQ01CD9JY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5384 JY8QFUQ01DNNFM No results 5385 JY8QFUQ01AB19P productive Homsap IGHV3-7*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca 5386 JY8QFUQ01BQ174 No results 5387 JY8QFUQ01CU36E productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5388 JY8QFUQ01DKUMI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 847 87.67 192/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-6*01 F 1 8 8 16 8.8.16 [2.17.38.11] CVRRGRQDTDSSEAFDIW in-frame - ggctctggatacacctttggcattcactggattgcctgggtgcgccagaagcccgggaaaggcctagagtggatggggatcatctatccaggcgactctgacaccacatacagtccgtccttccaaggccaagtcaccatctcagtcgacaagtccagcaataccgcctatttacagtggatcagcctgagggcctcggacaccgccatgtattattgtgtgagacggggcagacaagataccgactcgtctgaagcttttgacatttggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5389 JY8QFUQ01DE1OM productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 5390 JY8QFUQ01AC35C No results 5391 JY8QFUQ01AB26V unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 418 96.63 86/89 nt 8 3 X 8.3.X [1.17.X.X] null + No rearrangement found ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagta 5392 JY8QFUQ01DQ8CK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca 5393 JY8QFUQ01CXLSN No results 5394 JY8QFUQ01DRP9X No results 5395 JY8QFUQ01C6Z4J No results 5396 JY8QFUQ01AE1E1 productive Homsap IGHV3-49*04 F 984 93.72 209/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-15*01 F 1 8 10 11 8.10.11 [1.17.38.11] CTPWWRGGYFDYW in-frame + ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaaccatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccccgtggtggcggggaggttactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 5397 JY8QFUQ01DA71E productive Homsap IGHV3-64*02 F (see comment) 784 84.47 185/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVRGRPMAGFHGILYDNW in-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5398 JY8QFUQ01ATRK5 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaatgacacgtttgggagagaagactactgggggccagggaacccgtggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5399 JY8QFUQ01A7WON unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 588 81.36 144/177 nt 8 8 X 8.8.X [1.17.24.X] null - No rearrangement found Low V-REGION identity (81,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtgga 5400 JY8QFUQ01B6T0H productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'TC' (2 nucleotides at position 54 to 55 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagTCccccaggggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactca 5401 JY8QFUQ01BWHD3 No results 5402 JY8QFUQ01BHIPV productive (see comment) Homsap IGHV3-23*05 F 805 86.11 186/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKSTGHSGWYPFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); tctggattcacAgttcagcaattatgccatgggctgggtccgccaggctccagggaaggggctggagtAgggtcgctgctattgatggcagtggtgaaagaactcactatgcagactccgaacagggccgcgtcaacatctctagagacaattccaagaacatgatatatgtgcaattgagcagcctgagagccgaggacacggccatgtattactgtgtgaagtccaccgggcacagtggctggtatccctttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 5403 JY8QFUQ01CH60H productive (see comment) Homsap IGHV3-7*01 F 943 93.9 200/213 nt 92.96 198/213 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [0.16.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctggagtgggtAggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5404 JY8QFUQ01BUI58 productive (see comment) Homsap IGHV1-3*01 F 531 88.24 120/136 nt 87.5 119/136 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 X 13 8.X.13 [0.3.34.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 78 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacagcttcactaactacaatatccattggaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 5405 JY8QFUQ01BHU4V unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ3*01 F (see comment) 133 74.0 37/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CANELGYCSG## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctagagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaaggtcttgccccgctgagcctctgcagcaacccacgccagatgggaacatggtccatcgcctgcctggtccagggcttcttccccc 5406 JY8QFUQ01BE2CW No results 5407 JY8QFUQ01CX2NZ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5408 JY8QFUQ01C05JS unknown (see comment) Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F 92 52.31 68/130 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ttctggattcacctttggtgactatgctatgagctggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 5409 JY8QFUQ01C5S68 No results 5410 JY8QFUQ01C9UUV No results 5411 JY8QFUQ01C1E93 No results 5412 JY8QFUQ01BHV6G unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 657 77.88 169/217 nt 77.42 168/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.37.X] null - stop codons no junction found Low V-REGION identity (77,88% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgttttgcaaatgtacagcctggggccagggagccctggtcaccgtctcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5413 JY8QFUQ01CRSSS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKEIAVSGEGALDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcacAgtttagcaactatgccatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5414 JY8QFUQ01CVV8C unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 5415 JY8QFUQ01BUF2K No results 5416 JY8QFUQ01BBZ8A unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 535 92.06 116/126 nt 91.27 115/126 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD1-20*01 F 1 8 X X 8.X.X [1.6.26.11] CANASPV*LERI#YYYGMDVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccgtataactggaacgtatttctactactacggtatggatgtctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5417 JY8QFUQ01B1XL8 No results 5418 JY8QFUQ01CUJY2 No results 5419 JY8QFUQ01B09KA productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5420 JY8QFUQ01CQA8U No results 5421 JY8QFUQ01BNAB7 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 889 91.08 194/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); tcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgatcagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5422 JY8QFUQ01C8G2P unproductive (see comment) Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARESTWEFYS*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaattttactcctgactcctggggcccgggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5423 JY8QFUQ01ACIGI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 484 82.86 116/140 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 5424 JY8QFUQ01C10O9 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 678 79.91 171/214 nt 78.97 169/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'AGT' (3 nucleotides at position 137 to 139 in the user submitted sequence), (do not cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccCgtgaggggcgggcttatcgaAGTctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 5425 JY8QFUQ01AWKYO No results 5426 JY8QFUQ01DRPQO productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctggattcacttttagcagtttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaatgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 5427 JY8QFUQ01DJVMH unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 X 8.10.X [1.17.38.11] CATDFPYWI##AFDVW out-of-frame + stop codons Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggatttcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5428 JY8QFUQ01ATUBK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAMRFCGGPECYPYLDNW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcacattcagtaactactggatccactgggtccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 5429 JY8QFUQ01B15FC No results 5430 JY8QFUQ01BV55D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5431 JY8QFUQ01DH0MW productive Homsap IGHV3-74*03 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATGPDYAYAMW in-frame - cctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5432 JY8QFUQ01B47NI productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5433 JY8QFUQ01B2UDS No results 5434 JY8QFUQ01APY5Z productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5435 JY8QFUQ01CLWT1 No results 5436 JY8QFUQ01C5V24 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKELGRALTGNYYQYFHYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagGggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaattggggagggccctgactgggaactactaccagtactttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5437 JY8QFUQ01BF7T6 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggcggctgtgntctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga 5438 JY8QFUQ01B92KA unproductive Homsap IGHV3-72*01 F 1078 98.65 219/222 nt 98.2 218/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.16.38.11] CLRPPRYD#PG out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 5439 JY8QFUQ01CB12R No results 5440 JY8QFUQ01C9J7X unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 107 55.66 59/106 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5441 JY8QFUQ01CBHZ7 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARLGATR##DYW out-of-frame + stop codons ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttggggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactc 5442 JY8QFUQ01BX3WN unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 110 100.0 22/22 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found ctctggattcactttcagtaac 5443 JY8QFUQ01A65SY No results 5444 JY8QFUQ01BNPNB productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag 5445 JY8QFUQ01AMD1U productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5446 JY8QFUQ01DEEWB productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5447 JY8QFUQ01BY1KT unknown (see comment) Homsap IGHV3-38-3*01 ORF 102 53.03 70/132 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tgtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5448 JY8QFUQ01CST8T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtagtcgtcgcatgcctggtccagggcttcttccccca 5449 JY8QFUQ01C3FXA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5450 JY8QFUQ01BGOY9 No results 5451 JY8QFUQ01AR5SV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5452 JY8QFUQ01DCHJ0 No results 5453 JY8QFUQ01BKRRW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 446 66.97 146/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (66,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctctggattcagtatttataattattggatgaattgggtccgccaggctccagggagggggctggagtgggtggccagcattaaggcagacggaactgagaagacgtttggggactctgtgaagggccgattctccatctccagagacaacgcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 5454 JY8QFUQ01C05FJ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 705 81.31 174/214 nt 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 77 of V-REGION: 'T' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttgaTcgatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5455 JY8QFUQ01CI830 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttcccccgaaccggtgacggtgtcgtggaacctcag 5456 JY8QFUQ01AR9UF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5457 JY8QFUQ01AMUMN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 13 8.8.13 [1.17.38.11] CTRDSVSGDLVIDFW in-frame + ctctggattcaacttcaatttctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcgtctatcagtagaagtagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaacaactctctgcatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtacgagagattccgtgtccggtgacttagtcattgacttctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5458 JY8QFUQ01BAY6G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccaggggcttcttccccctagg 5459 JY8QFUQ01A0N2T unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 664 93.96 140/149 nt 8 8 X 8.8.X [1.17.15.X] null + No rearrangement found tctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaa 5460 JY8QFUQ01CGA88 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKQTIFDYYYGLDVW in-frame + ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5461 JY8QFUQ01C3V50 productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 5462 JY8QFUQ01CQ0U4 unproductive (see comment) Homsap IGHV3-7*02 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaagGggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 5463 JY8QFUQ01CS3O4 No results 5464 JY8QFUQ01BF7BK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca 5465 JY8QFUQ01CCHUM No results 5466 JY8QFUQ01CTP5B No results 5467 JY8QFUQ01CQY5C unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5468 JY8QFUQ01A7ZGP unknown (see comment) Homsap IGHV3-48*03 F 873 89.4 194/217 nt 88.94 193/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaGgttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5469 JY8QFUQ01BBZI9 productive Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 5470 JY8QFUQ01BBDCQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5471 JY8QFUQ01BN5VO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [0.17.38.11] CACYFDSNGFFDYW in-frame + tggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5472 JY8QFUQ01CJX2H No results 5473 JY8QFUQ01DU4YW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatggccgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5474 JY8QFUQ01CAS0F No results 5475 JY8QFUQ01CBQ8X unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 5476 JY8QFUQ01CIE27 No results 5477 JY8QFUQ01ATA2C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5478 JY8QFUQ01A7EEO No results 5479 JY8QFUQ01C38VZ No results 5480 JY8QFUQ01C6HDO No results 5481 JY8QFUQ01A38E4 No results 5482 JY8QFUQ01BBQPP No results 5483 JY8QFUQ01DRF9S No results 5484 JY8QFUQ01ATS0K No results 5485 JY8QFUQ01CPR0X No results 5486 JY8QFUQ01BQXYU productive Homsap IGHV3-11*01 F 882 89.86 195/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + ctctggattcatcttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggagtggatctcatacatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggtgattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5487 JY8QFUQ01A261C No results 5488 JY8QFUQ01BHG7H unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKVSSYESSGYYGGLF*LL# out-of-frame + stop codons ctctggattcacctttaccagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtgccagtggtggtagcacatactacgaagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatcttcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagtttcgtcctatgagagtagtggttattacggggggttattttgacttctggggtccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5489 JY8QFUQ01DV3UL unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt 80.47 173/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*02 F 3 8 7 X 8.7.X [1.17.38.11] CARAYTFHFWSGL##WYFDLW out-of-frame - Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggGggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatacttttcacttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5490 JY8QFUQ01DR4X2 No results 5491 JY8QFUQ01CKYJ1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 5492 JY8QFUQ01BZF3C No results 5493 JY8QFUQ01BE43V unknown (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5494 JY8QFUQ01B26IH unproductive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*03 F 567 94.49 120/127 nt 93.7 119/127 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 X X 8.X.X [0.3.31.11] CARGGRRGNYYWGI#DSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacacgttcaccgactactatgtccactggggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5495 JY8QFUQ01DSXYM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5496 JY8QFUQ01C3J6T unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 121 96.15 25/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctccggggacagtgtctctaccaaca 5497 JY8QFUQ01CNKUO unproductive (see comment) Homsap IGHV3-48*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARAGGWEI##YFDYW out-of-frame + stop codons ctctggattcatcttcagtcagtataaaatgaattgggtccgccaggctccagggaaggggctggagtgggtttcagaaattagttttagaagcagaaccgtacactacgcagactctgtgaggggccgcttcaccgtctccagagacaatgccaagaactcactgtatctacaattgaacagcctgagagacgaggacacggctatatattactgtgcgagagcggggggctgggagattcgactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5498 JY8QFUQ01DU2D9 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5499 JY8QFUQ01DSQKK productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5500 JY8QFUQ01CDMAR No results 5501 JY8QFUQ01AJRGU productive Homsap IGHV1-69*04 F, or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAIPFSSSSAWFDPW in-frame + tggaggcaccttcagcagctatgtcatcagctggctgcgacaggcccctggacaagggcttgagtggatgggacatgtcattcctatgtttggtgtatctaacctcgcgcagaggttccagggcagagtcacaataaccgcggacacatccacgaccacagcctacatggaggtgaccaggctgagatctgaagacacggccgtctattattgtgccataccattcagcagctcgtcggcctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5502 JY8QFUQ01CVCX4 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1025 97.67 210/215 nt 97.21 209/215 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 5503 JY8QFUQ01DVB70 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcagcgtctcctctgcatccccgaccagccccaaggtcttcctgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5504 JY8QFUQ01BYIVH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 652 92.16 141/153 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 X 8 13 X.8.13 [X.5.38.11] CARDCDSGECNFDYW in-frame + ctctgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5505 JY8QFUQ01BRVZA productive Homsap IGHV3-7*01 F 1003 96.3 208/216 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + tctggattcaccttcagtagcctttggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaacaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgggagccgaggatacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5506 JY8QFUQ01C68XM No results 5507 JY8QFUQ01BFND9 No results 5508 JY8QFUQ01B23M7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattattatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5509 JY8QFUQ01BBV45 No results 5510 JY8QFUQ01CAWQU No results 5511 JY8QFUQ01A9MZ5 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5512 JY8QFUQ01BM2LN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 13 8.8.13 [2.17.38.11] CATGAGNWNYIFNYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); gcctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgGgtttttatatatactacgcggattcagtgaagggccgagtcaccatctccagagacaacgccaagaattcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacatttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5513 JY8QFUQ01CITNO productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5514 JY8QFUQ01ADJUL unproductive (see comment) Homsap IGHV3-7*01 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CATSP*RL*QTMGVLG in-frame + stop codons in FR2-IMGT at codon 50 of V-REGION: 'GTG' (3 nucleotides at position 63 to 65 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccaggggaggggcGTGgagagtgggtggccaaTcataaagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctccccctagcgactttgacagacgatgggggtactgggggcccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5515 JY8QFUQ01CCWJO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARHSHSSGYSSLDALEIW in-frame + ttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcaatcccggtgactctgataccagatatagcccgtcctttcaaggccaggtcaccgtctcagccgacaggtccatcagtaccgcctacctgcagtggaaaagcctgagggcctcggacaccgccatgtattactgtgcgcgacactcccacagtagtggttattccagccttgacgctcttgagatctggggccaagggacaatggtcaccgtctcttctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5516 JY8QFUQ01CH5B1 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [2.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 5517 JY8QFUQ01AWVZF productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 554 92.97 119/128 nt 92.19 118/128 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 3 8 X 21 8.X.21 [1.8.25.11] CARLTPLTMVPGTHYYYHSMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 87 nucleotides (from position 54 in the user submitted sequence), (do not cause frameshift) tctctggtggctccatgactggttactactggagttggatccggcggcccccagtcgacacgtccaagaaccagttctctctgacgctgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagattgacacccctgactatggttccgggaactcactactattaccacagtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaagg 5518 JY8QFUQ01DQWVS No results 5519 JY8QFUQ01C8IQT No results 5520 JY8QFUQ01AZYT3 No results 5521 JY8QFUQ01CX8D2 productive (see comment) Homsap IGHV3-33*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ1*01 F 197 86.54 45/52 nt Homsap IGHD6-6*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDRQDARAEHLQYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); ctggattcatcttcagtaattatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggctgttctgtggttcaatggaaatacgaagtattatgcagactccgtgaagggccgcttcaccatctccagagacacatccacgaacacgctgtttttCgcaaatggacagcctgagagccgaggacacggctgtctattattgtgcaagagatcgtcaggacgcccgcgctgaacatctccaatactggggccagggcaccatggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca 5522 JY8QFUQ01A9CSP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD6-25*01 F 1 8 8 22 8.8.22 [1.17.38.11] CARYQGDTSGYQDVFYAHYGMDVW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttaggggctactggatgcactgggtccgtcaggttccaggtaaggcgccggagtggctcgcacgtctgaatactgatggagatagtacaagttatgcggactccgtgaagggccgcttcaccatctccagagacaacgccaggagcacattgttcctgcaaatgagcagtctgagagtcgaagacacggccatttattactgtgcacggtatcagggcgataccagtggctaccaggacgttttctacgcccactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgccctggtccagggcttcttccc 5523 JY8QFUQ01CMEIS No results 5524 JY8QFUQ01A6HZE unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 612 75.58 164/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5525 JY8QFUQ01CVDDP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 445 67.13 145/216 nt 66.67 144/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (67,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5526 JY8QFUQ01A5HLC No results 5527 JY8QFUQ01B5CX5 No results 5528 JY8QFUQ01DRKQS unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARLGPRFGD*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactggagctggatccCggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggccccggttcggggactgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5529 JY8QFUQ01DFFHG No results 5530 JY8QFUQ01DJSOV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctttttccccca 5531 JY8QFUQ01AEXEP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.16.38.11] CANWLSGTHSKFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggagggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 5532 JY8QFUQ01B53L4 No results 5533 JY8QFUQ01DEZRE productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5534 JY8QFUQ01A99VZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5535 JY8QFUQ01C43MC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 442 93.07 94/101 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 5536 JY8QFUQ01DQ69Q productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*08 F or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + ctctgcattcaccttcagtagttatgctatgcactgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5537 JY8QFUQ01BCX6J No results 5538 JY8QFUQ01CVXWU No results 5539 JY8QFUQ01CH61H No results 5540 JY8QFUQ01DW494 No results 5541 JY8QFUQ01AA6MU No results 5542 JY8QFUQ01AND5D unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ6*03 F (see comment) 37 65.0 13/20 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Other possibilities: Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity). The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgctatggcatgcactgggtccgccaggctccagggaaggGggctggcatgggtttcatacattagtgccagtagcagcaccaagtactacgcaaattctctgaagggccggttcaccatctccagagacaacgccaagaattcactgtatctggaaatcaacagcctgagcgacgaggacacgtctgtgtattactgtgcgcgagatgactacggcttcttcccca 5543 JY8QFUQ01AURX4 No results 5544 JY8QFUQ01CHUA2 productive Homsap IGHV3-7*01 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAISSGFYSTGYW in-frame + ctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 5545 JY8QFUQ01A85B5 No results 5546 JY8QFUQ01AFMGL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5547 JY8QFUQ01AKHRY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5548 JY8QFUQ01CVICZ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 116 55.65 64/115 nt 8 8 X 8.8.X [1.17.3.X] null - No rearrangement found gctctggattcagctttagttactattggatgagctgggtccgccaggctcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5549 JY8QFUQ01BE4S7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFDP## out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccagctcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5550 JY8QFUQ01CW7P5 No results 5551 JY8QFUQ01AUUYT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5552 JY8QFUQ01BT3YG No results 5553 JY8QFUQ01BO21D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5554 JY8QFUQ01APXOX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame - ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5555 JY8QFUQ01BUMGI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 651 99.25 132/133 nt 98.5 131/133 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 87 64.58 31/48 nt 8 X 17 8.X.17 [1.11.24.11] CAKFMGVVVVPAAHNWFDP (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT, from codon 50 of V-REGION: 84 nucleotides (from position 62 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctgggccaggaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5556 JY8QFUQ01CJ47C No results 5557 JY8QFUQ01CD2OW No results 5558 JY8QFUQ01CKCGQ unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRGGRGSSE#DAFDIW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatgggagtgagaaatactatgtcgactcagtgaggggccgatttaccatctccagagacaacgccgagagctcactgtatctgcagatgagcagcctgagagccgaggacacggctttatattattgtgtgagaggcgggaggggcagcagcgagaagatgcttttgacatttggggccaagggacaagcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5559 JY8QFUQ01DH95Z unproductive (see comment) Homsap IGHV4-61*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.37.11] CARDPRVICSGGSCRSSAMDV* in-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 158 in the user submitted sequence), (cause frameshift) tccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaaccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctgaggccaagggaccacggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 5560 JY8QFUQ01CYI8T productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5561 JY8QFUQ01CAW0A No results 5562 JY8QFUQ01ATEPS No results 5563 JY8QFUQ01DSN81 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga 5564 JY8QFUQ01CN7CX No results 5565 JY8QFUQ01A4GBM No results 5566 JY8QFUQ01AARSO No results 5567 JY8QFUQ01B4Z07 No results 5568 JY8QFUQ01DO78T No results 5569 JY8QFUQ01BJ5JH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 894 91.12 195/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 7 8 10 7.8.10 [1.16.38.11] CARDLYGADDLW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) ctctggattcaccttagtagatattggatgcactgggtccgccaagctccagggaagggctggtgtggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctcgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5570 JY8QFUQ01AG0MF No results 5571 JY8QFUQ01BAWN2 No results 5572 JY8QFUQ01BLWFY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 5573 JY8QFUQ01DV8FJ No results 5574 JY8QFUQ01DKH5M unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 423 91.92 91/99 nt 10 4 X 10.4.X [1.17.X.X] null + No rearrangement found tctctggcggctccatcagcagtactagttactactggacctggattcgccagcccccagggaaggggctggagtgggttgggagtgtctattatactg 5575 JY8QFUQ01C1FN1 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5576 JY8QFUQ01B775N productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gtctctggattcaccgtcaataGggaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5577 JY8QFUQ01CRJBD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*02 F 109 70.21 33/47 nt Homsap IGHD5-12*01 F 3 8 8 6 8.8.6 [1.17.38.11] CVSIGHGV in-frame + ctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtcgcacacattgacactgatgggagtatcgcagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatactttgtatctgcaaatggacagtctgagagccgacgacacggctatatattactgtgtaagcattggacacggagtgggcccgggaacccaggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 5578 JY8QFUQ01BBTQQ productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5579 JY8QFUQ01ATJ6D productive (see comment) Homsap IGHV3-11*01 F 1004 95.87 209/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 91 to 99 in the user submitted sequence), (do not cause frameshift); cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaTggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 5580 JY8QFUQ01DGOQL productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 735 81.74 179/219 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 10 7 18 10.7.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame + Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5581 JY8QFUQ01DN3IK No results 5582 JY8QFUQ01CAFUF No results 5583 JY8QFUQ01BP2N9 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctacattcacgtttagtcggtattggatgagctggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5584 JY8QFUQ01DEFDV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccctca 5585 JY8QFUQ01BTSMS No results 5586 JY8QFUQ01AUPU3 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5587 JY8QFUQ01CEFXQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggaAGgtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacaacctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5588 JY8QFUQ01ALW7I productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5589 JY8QFUQ01B9N93 productive Homsap IGHV3-9*01 F 787 85.19 184/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVKDLSGRPKDMHGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctgggttcagttttagcaattatgccatgcactgggtccgtcaagctccagggaagggcctgcaatgggtctcacgtattaattggaacagtggaaacatagcctatgcggcctctgtgaggggccgattcaccgtctccagagacgacgccgagcactccctgtatttacaaatgaatggtctgacaactgaagacacggccttatactattgtgtgaaagatttgtctggccgaccaaaggacatgcacggcatggacgtctggggccaagggaccacggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaaacgtggtcatcgcctgcctggtccagggcttcttccccca 5590 JY8QFUQ01C65QU productive (see comment) Homsap IGHV3-7*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 5591 JY8QFUQ01C1QRL No results 5592 JY8QFUQ01C1IP6 No results 5593 JY8QFUQ01CSU0E No results 5594 JY8QFUQ01C1YFI productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame - ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggagggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5595 JY8QFUQ01DU77L productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5596 JY8QFUQ01CDQJC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ6*04 F 99 64.81 35/54 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNELGYCSG## out-of-frame + ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggcagggaggccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5597 JY8QFUQ01BNCCQ productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5598 JY8QFUQ01COPIL No results 5599 JY8QFUQ01BJBTV productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 84.62 187/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5600 JY8QFUQ01A1BK7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 5601 JY8QFUQ01DER7D No results 5602 JY8QFUQ01ASNS2 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 7 16 8.7.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5603 JY8QFUQ01B7YKQ No results 5604 JY8QFUQ01ASIHL No results 5605 JY8QFUQ01AP72B productive (see comment) Homsap IGHV3-7*01 F (see comment) 742 82.87 179/216 nt 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5606 JY8QFUQ01BDAG5 No results 5607 JY8QFUQ01CZVO7 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaatagGAaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5608 JY8QFUQ01CWJGM No results 5609 JY8QFUQ01CJTJ0 No results 5610 JY8QFUQ01BZ8WK productive Homsap IGHV3-66*02 F 868 89.35 193/216 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [2.17.38.11] CAAVGVGSAVSFQYW in-frame - gcctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttattacggtggaaccacatattacgctgactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5611 JY8QFUQ01BHPIN No results 5612 JY8QFUQ01A04UM No results 5613 JY8QFUQ01AGS3S No results 5614 JY8QFUQ01BUS72 unproductive Homsap IGHV3-21*04 F 909 91.24 198/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGEGQGWNY#YYGMDVW out-of-frame - ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcatcatctccagggacaacgccaagaactcactgtctctgcagatgaacagcctgagagccgacgacacggccgtctattattgtgctcggggggaagggcaagggtggaactacctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5615 JY8QFUQ01ASD77 productive Homsap IGHV3-43*01 F 949 93.52 202/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD3-16*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKWAPTGVMGPMPLIFG in-frame + tctggattcatatttgaagactataccatgcactgggtccgtcaagctccggggaagggtctggagtgggtctctcttattaattgggatggtggtaacacatactatgcagactctgtgaagggccgattcaccatctccagagacaacaacaagaactccctgcaaatgcaaatgaacagtctgagaactgacgacaccgccttgtatttttgtgcaaaatgggctcctacgggagttatgggtccgatgcctttgatttttggggcccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 5616 JY8QFUQ01DXF5F productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFLTTG in-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttgactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 5617 JY8QFUQ01AVPIU unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 81 56.94 41/72 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5618 JY8QFUQ01BAMJG productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5619 JY8QFUQ01BVBT9 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 871 87.84 195/222 nt 87.39 194/222 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.37.11] CTADVPSPLAQNDF# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 166 in the user submitted sequence), (cause frameshift) ctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctgggccagggaaccctggtcaccgtctcctcagnatccccggacagccccaaaggtcttcccgctgagcctccgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5620 JY8QFUQ01C3X43 No results 5621 JY8QFUQ01BZNDE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5622 JY8QFUQ01C0HLO unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDYYDGRDYV# out-of-frame + gtctggattcaaattcaacagcagtggcatgcactgggtccgccaggctccaggcaagggactggagtggctgtcagttatatggtttgatggcagtcatcaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactttttctgcagatggacagcctcagagtcgaagacacggctgtctattactgtgcgagagactactatgatggtcgtgattatgtctgggccacggaaccctggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5623 JY8QFUQ01DCZXP productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5624 JY8QFUQ01CZ46G No results 5625 JY8QFUQ01DV3XT unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARDSALFGYARYDAMDA## out-of-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggcccaagggaccgcggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5626 JY8QFUQ01BPLRY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 450 67.28 146/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (67,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5627 JY8QFUQ01CR28R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5628 JY8QFUQ01AZS32 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); tctctggtgGgctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5629 JY8QFUQ01AV2VI productive (see comment) Homsap IGHV3-48*03 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ6*02 F (see comment) 185 81.82 45/55 nt Homsap IGHD1-1*01 F 3 7 8 10 7.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggattcgccttcaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcaccccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg 5630 JY8QFUQ01BDYY2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGQFGTVMDYW in-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggatggggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgttttttattgtgcgaaaggccagtttggtaccgtcatggactattggggccagggaacccaggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcctgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5631 JY8QFUQ01DJPXI productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5632 JY8QFUQ01B6KS0 productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5633 JY8QFUQ01CBHVO productive Homsap IGHV1-8*01 F 921 92.52 198/214 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [0.17.38.11] CARARGVESSGIYVYHFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcaccacttatgacatcaactgggtgcgacaggccgccggacaagggcttgagtggatgggatgggtgaaccctgtcactggtaacacaggctatatacagaagttccagggcagagtcaccatgaccatgagcacctccacaagcacagcctacatggagctgagcagcctgaaatctgacgacacggccgtgtattattgtgcgagagcccggggggtagaaagttcggggatctacgtgtatcactttgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 5634 JY8QFUQ01CEIHZ productive Homsap IGHV1-3*01 F (see comment) 351 73.53 100/136 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 X 7 14 X.7.14 [X.X.38.11] CARGRYDSSGRGHEYW in-frame - Low V-REGION identity (73,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccagtttcagtatccattggaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5635 JY8QFUQ01AW8CJ No results 5636 JY8QFUQ01B715G No results 5637 JY8QFUQ01DKFB0 productive Homsap IGHV3-21*04 F 959 93.58 204/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame - cctctggattcgcctttaatacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtacttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaacctgagagccgaagacacggccgtgtattactgtgcgagagccgtttcgcatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5638 JY8QFUQ01B1M13 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 559 93.02 120/129 nt 92.25 119/129 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 3 8 X 21 8.X.21 [2.8.25.11] CARLTPLTMVPGTHYYYHSMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 87 nucleotides (from position 55 in the user submitted sequence), (do not cause frameshift) gtctctggtggctccatgactggttactactggagttggatccggcggcccccagtcgacacgtccaagaaccagttctctctgacgctgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagattgacacccctgactatggttccgggaactcactactattaccacagtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5639 JY8QFUQ01CG8MB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 5640 JY8QFUQ01BDRV8 No results 5641 JY8QFUQ01BIY56 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - gcctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5642 JY8QFUQ01BAU9M productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5643 JY8QFUQ01CN8OF unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 607 75.46 163/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5644 JY8QFUQ01DAM03 unproductive (see comment) Homsap IGHV1-2*02 F 915 92.89 196/211 nt 92.42 195/211 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 7 8 15 7.8.15 [X.17.37.11] CARGGRRGNYYWES*LW in-frame + stop codons in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) gatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattgggaatcttgactctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5645 JY8QFUQ01DCJ87 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 148 53.19 100/188 nt 8 7 X 8.7.X [2.17.28.X] null - No rearrangement found gcctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5646 JY8QFUQ01CNSR0 No results 5647 JY8QFUQ01CA64I No results 5648 JY8QFUQ01ASWWE No results 5649 JY8QFUQ01DLV58 No results 5650 JY8QFUQ01DMF5R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaTcctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5651 JY8QFUQ01C0P6M No results 5652 JY8QFUQ01BGM91 No results 5653 JY8QFUQ01B4OGW productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca 5654 JY8QFUQ01CT9DG No results 5655 JY8QFUQ01CAVOQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgagaacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5656 JY8QFUQ01AHJIA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtggaactcag 5657 JY8QFUQ01C870Y No results 5658 JY8QFUQ01BV6IJ unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5659 JY8QFUQ01DIAOX productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + ctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5660 JY8QFUQ01A0ARS No results 5661 JY8QFUQ01ASCOV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5662 JY8QFUQ01APIM1 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 418 84.48 98/116 nt 82.76 96/116 nt 8 7 X 8.7.X [1.17.5.X] null + No rearrangement found Low V-REGION identity (84,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) tctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgttctacttacaccatttctacgcagagtctg 5663 JY8QFUQ01CX9WG No results 5664 JY8QFUQ01CKAO6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKLGVAATTWNFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'GCC' (3 nucleotides at position 47 to 49 in the user submitted sequence), (do not cause frameshift); ccgtctggattcacctttaccacctGatgccatgagctgggctccgGCCagggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5665 JY8QFUQ01DU0GX No results 5666 JY8QFUQ01BIRVF No results 5667 JY8QFUQ01A3W95 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5668 JY8QFUQ01CZJPK No results 5669 JY8QFUQ01CCDPI No results 5670 JY8QFUQ01BKBQY productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVRHTAMERGDYW in-frame - ttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggcccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 5671 JY8QFUQ01BYXN5 No results 5672 JY8QFUQ01CAF5A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5673 JY8QFUQ01CGP6U No results 5674 JY8QFUQ01B8JVX No results 5675 JY8QFUQ01DJE9I productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 723 80.72 180/223 nt 79.82 178/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYHSTYPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'CT' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); ctctggattcgccttcaatatcaagtggatgagttgggtccgccaggcCTggccggggaagggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaaGtacactgtacttgcacatgaccggcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5676 JY8QFUQ01ATCC4 No results 5677 JY8QFUQ01AE1S4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5678 JY8QFUQ01A3YHO productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 806 85.78 187/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.37.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 89 of V-REGION: 1 nucleotides (from position 173 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 183 in the user submitted sequence), (cause frameshift) ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctcctgaggttgagtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtggaactca 5679 JY8QFUQ01CJPMP productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-16*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARVGWADYRDTFEIW in-frame + ttctggatacacttttcccaactattggatcgcctgggtgcgccagatgcccgggaaagacgtggagtggatggggatcatctatcctgacgactctgacaccgcgtacagcccgtccttccaaggccaggtcaccatctcagtcgacaagtccatcagtaccgtctacttgcagtggaacagcctgaaggcctcggacaccgccatgtattactgtgcgagggtcggctgggcggattaccgggatacttttgaaatctggggccaagggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5680 JY8QFUQ01A12V0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5681 JY8QFUQ01DDE1I productive (see comment) Homsap IGHV3-48*01 F 991 94.98 208/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'CG' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaTggggctggagtCGggatttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5682 JY8QFUQ01DQEVL No results 5683 JY8QFUQ01A05HF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgccagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5684 JY8QFUQ01CJF89 productive (see comment) Homsap IGHV3-48*01 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKVGSMNIEASPPDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gtctctggattcaGcgttcagttcctatagcatgagctgggtccgccaggctccggggaagggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgaacagcctgagagccgaggacacggccgtctattactgtgcgaaagttggcagcatgaatatcgaggcgagccctcctgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5685 JY8QFUQ01A3HBC No results 5686 JY8QFUQ01A9OA6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5687 JY8QFUQ01ALKF4 productive (see comment) Homsap IGHV4-61*02 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.37.11] CARDTGQTYGRGPLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 125 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 215 in the user submitted sequence), (cause frameshift) ctctggtgcctccataaataggggtaattattactggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttattttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5688 JY8QFUQ01BOE5V productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - ctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5689 JY8QFUQ01DOOXI No results 5690 JY8QFUQ01CTNAN productive Homsap IGHV4-39*02 F (see comment) 758 82.81 183/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtatctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgaggtgtcgtggaact 5691 JY8QFUQ01AGKAA productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5692 JY8QFUQ01B0WSW No results 5693 JY8QFUQ01DEZDE productive Homsap IGHV4-61*01 F 969 93.64 206/220 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD4-17*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARCDYGDFDDAFDLW in-frame + ctctggtggctccgtcagaagtgggaattactactggagctggatccggcagcccccagggaagggactggagtccattgcatatatctcttacagtgggagcaccacctacagcccctccctcaagggtcgagtcaccatatcagtagacacatccaagaaccagttctccctgagcctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgaggtgtgactacggtgactttgatgatgcttttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5694 JY8QFUQ01CIJWA unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca 5695 JY8QFUQ01CQBJM unproductive Homsap IGHV3-48*02 F 1036 97.26 213/219 nt 96.8 212/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [2.17.38.11] CAREITILD#GVDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); gcctctagattcaccttcagtagctatagcatgGaactgggtccgccaggctcgagggaaggggctggagtgggtttcatacatcagtggtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagagattacgattttggataggtgtggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5696 JY8QFUQ01C2DN4 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 835 86.04 191/222 nt 85.59 190/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [1.17.37.11] CTADVPSPLAQNDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 85 of V-REGION: 2 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) ctctgggggtcaccttcagtgacgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5697 JY8QFUQ01AYOU8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.16.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) gtctggatcacatttagaagctattccagaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggAtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctcaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactnag 5698 JY8QFUQ01B9O0K unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 134 58.49 62/106 nt 57.55 61/106 nt 8 8 X 8.8.X [0.16.2.X] null + No rearrangement found in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cggttacattgttaccacctctggtttcagctgggtgcgacaggccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5699 JY8QFUQ01DIGET productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5700 JY8QFUQ01DUQ53 productive (see comment) Homsap IGHV3-7*01 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARGTSVDPGIDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); tctggattcaccTtttagtaattattggatgcactgggtccgccaggtttcaggggaGGggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5701 JY8QFUQ01DWYS5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgAaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5702 JY8QFUQ01B0JP3 No results 5703 JY8QFUQ01BWTPC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARDNYGDY## out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 90 to 91 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5704 JY8QFUQ01ADY64 No results 5705 JY8QFUQ01DPHPE No results 5706 JY8QFUQ01A1183 productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame + tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5707 JY8QFUQ01DH71V productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 5708 JY8QFUQ01CT7CJ No results 5709 JY8QFUQ01DF1RT unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 5710 JY8QFUQ01CAWGX No results 5711 JY8QFUQ01CGVI4 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 760 83.8 181/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [2.17.38.11] CARERGSGPPTGMDVW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ggttatgggttgaccgtcggtgccgaccacatgtactggtgccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcggggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5712 JY8QFUQ01DB2VE productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 5713 JY8QFUQ01CFBXF No results 5714 JY8QFUQ01B710M productive Homsap IGHV4-61*02 F 987 94.55 208/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - ctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5715 JY8QFUQ01ACSDM No results 5716 JY8QFUQ01DDK6P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARHGSGWLQELDYW in-frame + tctctggtggctccatcatcagagacagtgcctactggggctggatccgccagcccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 5717 JY8QFUQ01DSPOV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSAPHYGSGSYTKD## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaatcggctccccactatggttcggggagttatacaaaagattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5718 JY8QFUQ01C026R No results 5719 JY8QFUQ01AKG4H productive (see comment) Homsap IGHV4-61*02 F 875 90.57 192/212 nt 88.21 187/212 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.16.37.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGTTA' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 209 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtacTGGTTAttactactgGgagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaaccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtattttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5720 JY8QFUQ01CF631 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1039 96.0 216/225 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CARGSSRGGRSDVNYYELDF## out-of-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccaggggaatcctggtcaccgtctcctcagcatccccgaccagcccaaggtcttccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcagggcttcttcccccc 5721 JY8QFUQ01BO8GF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 650 83.24 154/185 nt 82.7 153/185 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.15.38.11] DSRNPRV# out-of-frame - Low V-REGION identity (83,24% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); agtgggtccgccaggctccagggaaggggctggagtgggtctcagGgcgtttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5722 JY8QFUQ01CGI06 No results 5723 JY8QFUQ01CB3OD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5724 JY8QFUQ01BA1XT No results 5725 JY8QFUQ01BLD4K productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 5726 JY8QFUQ01DDLX7 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 5727 JY8QFUQ01DHSQI productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5728 JY8QFUQ01CIOEQ unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRAGFGELSGFDC## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggGggagggggctgaagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggtccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5729 JY8QFUQ01C5RGO No results 5730 JY8QFUQ01BTQMW No results 5731 JY8QFUQ01DU06W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtggAtaccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5732 JY8QFUQ01B4AO7 No results 5733 JY8QFUQ01A9KBS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tctctggtggctccatgagcagtggtaattactgctggggctggggccgccagccCcccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtCcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 5734 JY8QFUQ01A33R5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtgtatatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5735 JY8QFUQ01ASBP2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5736 JY8QFUQ01CE8RF No results 5737 JY8QFUQ01CNLH7 No results 5738 JY8QFUQ01AOGK9 unproductive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFGIL# out-of-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttggaatactggggccaggggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctggctgcctggtcaagactacttcccgaaccggtgacggtgtcgtggaactcagg 5739 JY8QFUQ01B8IR4 No results 5740 JY8QFUQ01CH4BC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5741 JY8QFUQ01BJ29C No results 5742 JY8QFUQ01CWN98 No results 5743 JY8QFUQ01BIHAR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 5744 JY8QFUQ01BVE56 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.16.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaagggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactcag 5745 JY8QFUQ01DXHAD No results 5746 JY8QFUQ01B1PGP No results 5747 JY8QFUQ01DBCEI productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1031 95.15 216/227 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD7-27*01 F 3 10 9 13 10.9.13 [1.17.38.11] CVRDVGWGLDTLDIW in-frame - tctccggggacagtgtctccagcaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatattacaggtccaagtggtacactgattatgcactttctgtgaaaagtcgaataaccatcaacccggacacatcaaagaaccacttctccctgcagctcaactctgtgactcccgaggacacggctctgtattactgtgtaagagacgtcggctggggacttgatactcttgatatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5748 JY8QFUQ01DFRKG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 804 86.45 185/214 nt 85.98 184/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWALMPLISG in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggCtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctgggcgctgatgcctttgatatctggggcccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 5749 JY8QFUQ01DE8MP No results 5750 JY8QFUQ01AL0W5 No results 5751 JY8QFUQ01C4OTS unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5752 JY8QFUQ01CJZ68 No results 5753 JY8QFUQ01ACOXP No results 5754 JY8QFUQ01AQIAM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 5755 JY8QFUQ01BWVS1 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5756 JY8QFUQ01ALJK1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5757 JY8QFUQ01BKNWV No results 5758 JY8QFUQ01AXLVO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'AT' (2 nucleotides at position 82 to 83 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacgaaATtcaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5759 JY8QFUQ01ADJWN No results 5760 JY8QFUQ01ASTE5 No results 5761 JY8QFUQ01DWYRX No results 5762 JY8QFUQ01DQNN6 No results 5763 JY8QFUQ01A0XKT unproductive Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CVRGRDGVNFGEMDY## out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactgggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5764 JY8QFUQ01BULWJ No results 5765 JY8QFUQ01A8LEY productive (see comment) Homsap IGHV3-48*01 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag 5766 JY8QFUQ01C6GE7 unproductive Homsap IGHV1-8*01 F (see comment) 768 84.58 181/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGSLDQGGLPQI#W out-of-frame + Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cggatacaccttcagcagttatgatatcaactgggtgcgacaggccactggacgagggcctgaatggatggggtggatgagccctagcggtggtcatgcaaactatgcccagagattccagggcagaatcaccatgaccagggacacctccacaagcacagccttcttggaactaaacagcctgaaacttgaggatacagccatatattattgtgcgcgaggatccctcgaccaaggtggcctcccccaaattctggggccagggcaccctggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtccatcgcctgcctggtccagggcttcttcc 5767 JY8QFUQ01B9Z1X No results 5768 JY8QFUQ01A9ZDI productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5769 JY8QFUQ01DV2UQ No results 5770 JY8QFUQ01DQUUW unknown (see comment) Homsap IGHV3-74*03 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5771 JY8QFUQ01A8BUH unknown (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 673 79.81 170/213 nt 78.87 168/213 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (79,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'AGG' (3 nucleotides at position 58 to 60 in the user submitted sequence), (do not cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) tctggattcagctttagcgattttgccatgagttgggtccgccaacctccagggaaaAGGgggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5772 JY8QFUQ01AR1IO No results 5773 JY8QFUQ01C83FO No results 5774 JY8QFUQ01AXV0U No results 5775 JY8QFUQ01A4GO0 No results 5776 JY8QFUQ01ANRW2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 661 78.24 169/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5777 JY8QFUQ01BVAXI No results 5778 JY8QFUQ01CA0DL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.16.37.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) agcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5779 JY8QFUQ01B2ERL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame + ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 5780 JY8QFUQ01AW9L1 unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5781 JY8QFUQ01BC0BC No results 5782 JY8QFUQ01A9MLL productive Homsap IGHV3-9*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CVKDRKGSNWYYFENW in-frame - gcctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5783 JY8QFUQ01DBXSG productive Homsap IGHV4-39*03 F 907 90.05 199/221 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [2.17.38.11] CTREGPYYYGMDVW in-frame - tgctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5784 JY8QFUQ01BMWXL No results 5785 JY8QFUQ01A96PZ No results 5786 JY8QFUQ01CQ0KE No results 5787 JY8QFUQ01A4D1L unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 825 86.36 190/220 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [1.17.38.11] CARAGGWT#YFDSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactatgctggggccaccaacctcgccccctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggacccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5788 JY8QFUQ01A1Z5H productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5789 JY8QFUQ01C1E8G No results 5790 JY8QFUQ01BECOA productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5791 JY8QFUQ01AIS6M No results 5792 JY8QFUQ01ABZCV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.5 206/218 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGRIVSVGMSGWF#PW out-of-frame - cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgaccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5793 JY8QFUQ01DKDN0 No results 5794 JY8QFUQ01BWMN8 No results 5795 JY8QFUQ01A53DW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARIWDSWSGAFDV## out-of-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtgggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5796 JY8QFUQ01DLGU1 unproductive Homsap IGHV1-8*01 F 822 87.38 187/214 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGRGYGSYADH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5797 JY8QFUQ01DABH5 No results 5798 JY8QFUQ01CP34G No results 5799 JY8QFUQ01DR4R2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggaGttcacgtttgacgactatgccatgagttgggtccgccaggctccagggaaggggccggagtCgggtctcaggtattattcctaatagtcgtgacagacactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagagcacagtgtatctgcaaatgaacaacctcagaggcgaggacacggccgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5800 JY8QFUQ01DKOBD No results 5801 JY8QFUQ01C5KXD No results 5802 JY8QFUQ01DESK4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.16.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 153 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaagggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtcgtggaactcag 5803 JY8QFUQ01CRF17 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 861 88.18 194/220 nt 87.73 193/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.16.38.11] CAKLGYIWDTGRAGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatcggcgatagtagtttctcatggggctggatccgccagccccagggaagggcctggagtggattgggagcatctattacagtgggggcacctattacaacccgtccctcgagagtcgagtcatcatgtccgtagacacgtccaggaatcagttctctctgagactgagtcttatgaccgccgcagacacggctctctattactgtgcgaaactgggctatatttgggataccgggcgcgcgggtgactactggggccatggaacactggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5804 JY8QFUQ01CCKX0 No results 5805 JY8QFUQ01C60D2 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5806 JY8QFUQ01CBYIA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); cctcggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5807 JY8QFUQ01ADHKE No results 5808 JY8QFUQ01CUNSQ productive Homsap IGHV4-39*03 F, or Homsap IGHV4-39*07 F 919 91.28 199/218 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 10 7 12 10.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5809 JY8QFUQ01ADP3H unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 5810 JY8QFUQ01CKFOJ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 5811 JY8QFUQ01C3SL5 unproductive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5812 JY8QFUQ01C9SFZ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.37.11] CVRSEYSS#NWFDPW out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 81 of V-REGION: 1 nucleotides (from position 147 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggCctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagcaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaacgatggacgtggtcgtcgcatgcctggtccagagcttcttccccca 5813 JY8QFUQ01AVKCR No results 5814 JY8QFUQ01BFOLT No results 5815 JY8QFUQ01BX4HY unknown (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5816 JY8QFUQ01DR2NZ No results 5817 JY8QFUQ01CCRWD No results 5818 JY8QFUQ01B4SY2 unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 742 82.87 179/216 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-12*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKGTWIQ*LRPRLLG in-frame + stop codons Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaagggacgtggatacaatgactacggcctcgactactgggggcccggggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 5819 JY8QFUQ01CF0JA productive Homsap IGHV3-33*05 F 945 93.09 202/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD6-19*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAKSRTAVPGDNPW in-frame + gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaccagcctgagagccgcggacacggctgtttatcattgtgcgaaaagtaggacagcagtgcctggggacaacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5820 JY8QFUQ01BO84R unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 739 91.91 159/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgc 5821 JY8QFUQ01C83SA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5822 JY8QFUQ01DNBZ9 No results 5823 JY8QFUQ01AN3XQ unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 921 90.58 202/223 nt 90.13 201/223 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); ctctggattcaccctcGaaaaacgcctggacgagctgggtccgccagggtccagggaaggggctggagtgggttggccgcattaagagcaaatctgaaggtggggcaatagactacgctgcacccgtgaagggcagatttaccatctcaagagatgattcagaagacacactgtttctgcaaatgaacagcctgagagccgaggacacagccgtgtattattgtgccacgcacggtggtccagggcttcttccccca 5824 JY8QFUQ01DNPP4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggagtggtctcacacgtaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5825 JY8QFUQ01CNHW0 No results 5826 JY8QFUQ01BAU8T unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 5827 JY8QFUQ01AJIXB productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 870 88.64 195/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame + ctctggtgactccattggtagcagtgcctactactggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 5828 JY8QFUQ01DA284 No results 5829 JY8QFUQ01ALBMO No results 5830 JY8QFUQ01BDT61 productive Homsap IGHV3-7*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame - tctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5831 JY8QFUQ01BQT4D No results 5832 JY8QFUQ01AAXJQ No results 5833 JY8QFUQ01BRVNG No results 5834 JY8QFUQ01DC45W unproductive (see comment) Homsap IGHV4-61*02 F 978 94.09 207/220 nt 93.18 205/220 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CATVARRG##FDIW out-of-frame + stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift); ctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccTgcagacacggccgtttattactgtgcgacagtggcgcgccggggggtcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5835 JY8QFUQ01CE57J productive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 5836 JY8QFUQ01CMI9B No results 5837 JY8QFUQ01CITYD productive (see comment) Homsap IGHV3-11*01 F 909 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.37.11] CARRLLSSGWPPHEWGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 158 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaagggactggagtgggtctcatatattagcagtactggtggttccatatattacgcagactctgtgaagggccgcttcaccacctccagggacaacaccaaaactcaatgtctctgcaaatgaacagcctgagcgtcgacgacacgggcgtctattattgcgcgagaaggcttctcagtagtggatggccaccccacgagtggggcttctggggccagggagtccaggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5838 JY8QFUQ01B3QTZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt Homsap IGHJ5*02 F 205 88.24 45/51 nt Homsap IGHD3-3*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARSYGFSRFDPW in-frame + tctctggtggctccatcaccagtagtctttaccgctggggctggatccgccagtccccagggaagggcctggagtggatagggaatatcttttatggtgggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtnaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5839 JY8QFUQ01B5VR4 productive Homsap IGHV1-24*01 F 970 95.31 203/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 5840 JY8QFUQ01BZ5TN No results 5841 JY8QFUQ01B7QYW No results 5842 JY8QFUQ01CUX3B productive (see comment) Homsap IGHV3-NL1*01 F (see comment) 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CUX3B ; 8 AA in Homsap_IGHV3-NL1*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tgtctggattcagtttcagtagcttttGgcatgcactgggtccgccaggctccaggcaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5843 JY8QFUQ01CZOQU productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'AT' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); tctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagATggggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5844 JY8QFUQ01DBGHI productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggatacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5845 JY8QFUQ01APYE6 productive (see comment) Homsap IGHV3-69-1*02 P 925 92.96 198/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 7 10 8.7.10 [2.16.38.11] CARDDKWAFDYW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 79 in the user submitted sequence), (do not cause frameshift) gtctctggattcaccttcagtgactacagcatgaactgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 5846 JY8QFUQ01A89V5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 5847 JY8QFUQ01DW31H No results 5848 JY8QFUQ01C98AS productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5849 JY8QFUQ01AF98H No results 5850 JY8QFUQ01DIDF1 No results 5851 JY8QFUQ01CYQ4L unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 474 82.61 114/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 5852 JY8QFUQ01BALAC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 962 94.42 203/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'C' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgGcactgggtCccgccaagctccagggaagggctggttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccagga 5853 JY8QFUQ01DB2XW No results 5854 JY8QFUQ01DL8RT No results 5855 JY8QFUQ01BYP0E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5856 JY8QFUQ01AWXY3 No results 5857 JY8QFUQ01B80XQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag 5858 JY8QFUQ01BBPNM unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5859 JY8QFUQ01A2ANY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggttcagggcttcttccccca 5860 JY8QFUQ01AJH7W No results 5861 JY8QFUQ01BD95E unknown (see comment) Homsap IGHV2-5*03 F 177 54.69 105/192 nt 10 7 X 10.7.X [9.17.26.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5862 JY8QFUQ01CHRPW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-3*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKDVVMGFVAFDVW in-frame - atctggattcacctttaccaattttgccatgagctgggtccgccaggctccagggagggggctggagtgggtctcaggtattagtgctcgtggtagtagtgcgtactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcagatgaacagcctgagagccgaagacacggccgtatattattgtgtgaaagatgttgttatgggattcgttgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5863 JY8QFUQ01AGTKS productive Homsap IGHV3-9*01 F (see comment) 769 84.26 182/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5864 JY8QFUQ01A0F0Q No results 5865 JY8QFUQ01B0BQ5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5866 JY8QFUQ01CWRS4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 5867 JY8QFUQ01C2NRC No results 5868 JY8QFUQ01BGB63 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 208 80.0 52/65 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggcttcttcccc 5869 JY8QFUQ01DSBTB No results 5870 JY8QFUQ01BCPR0 productive Homsap IGHV3-48*01 F 886 89.86 195/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactanagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5871 JY8QFUQ01AMV2H productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaact 5872 JY8QFUQ01BWRLY unproductive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F (see comment) 741 81.25 182/224 nt Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 2 8 10 13 8.10.13 [1.17.38.11] CAITKNDVWGGADQ* in-frame - stop codons Low V-REGION identity (81,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggttcantttcagtggctcttctgttcactgggtccgccagacttccggaaaagggctggagtggattggccgtatcagaagtaaggcgaacgataacgcggcagtgtatcgtaagccgctgacgggcaggtttttcatctccagagatgattcacagagcacggcatatctgcaactgaacaacctgggagtcgacgacacggccacatattactgtgctatcactaaaaacgatgtttggggcggcgctgaccagtgaggccaggggaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5873 JY8QFUQ01AT0CV productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5874 JY8QFUQ01BOE5N No results 5875 JY8QFUQ01AY7N1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 5876 JY8QFUQ01ACLRQ productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame - tctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5877 JY8QFUQ01C9TC2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagGggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5878 JY8QFUQ01B5XB0 No results 5879 JY8QFUQ01CAJHT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5880 JY8QFUQ01A7ZVA unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNRCWPTLVLLRYGRFG# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5881 JY8QFUQ01CVKEH unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 994 95.83 207/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5882 JY8QFUQ01B1JFN unproductive Homsap IGHV4-59*02 F 894 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGGSGGAYWNLIRG#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'GAT' (3 nucleotides at position 20 to 22 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 107 to 118 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagaGATttttattactggagttgggtccggcagcccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagaggtgggtccggtggggcctactggaatctgatccggggactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5883 JY8QFUQ01ARNEJ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 798 85.0 187/220 nt 83.64 184/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GACTC' (5 nucleotides at position 26 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 31 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) tctctggtgactcccatcgagtagtGACTCagttactattggtgctggatccggcagGcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5884 JY8QFUQ01DUSX9 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5885 JY8QFUQ01AZ8E6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5886 JY8QFUQ01CD1AQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5887 JY8QFUQ01CVGTZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 935 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - tctctggattcaccgtcaatagaaactacatgagttgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5888 JY8QFUQ01DPOAQ No results 5889 JY8QFUQ01CYEFE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccag 5890 JY8QFUQ01B5OHS No results 5891 JY8QFUQ01B8DGT No results 5892 JY8QFUQ01CBY02 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 136 64.86 48/74 nt 8 X X 8.X.X [1.15.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgt 5893 JY8QFUQ01DVFXJ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame - Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5894 JY8QFUQ01BWFKV productive Homsap IGHV1-3*01 F 956 94.81 201/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 7 8 9 7.8.9 [X.17.38.11] CARWNNDLDYW in-frame + gatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5895 JY8QFUQ01DSDAK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 947 92.31 204/221 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGASIARLRYGRL# out-of-frame - cagcctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggggcctcgatcgcgcggctacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5896 JY8QFUQ01DJCMC No results 5897 JY8QFUQ01CSGJC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5898 JY8QFUQ01DW1EC No results 5899 JY8QFUQ01DC0FC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5900 JY8QFUQ01B6UPU No results 5901 JY8QFUQ01C5NZ5 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5902 JY8QFUQ01C9EYH No results 5903 JY8QFUQ01DLA1D productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 97.22 210/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5904 JY8QFUQ01CSA2T unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5905 JY8QFUQ01DINCJ productive (see comment) Homsap IGHV3-13*01 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [1.17.38.11] CAREVTRLTVPYYLYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 191 to 191 in the user submitted sequence), (cause frameshift); ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccGggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatcctcgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 5906 JY8QFUQ01C3Y8K No results 5907 JY8QFUQ01CX5BS unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 559 73.06 160/219 nt 70.78 155/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - stop codons no junction found Low V-REGION identity (73,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 45 of V-REGION: 'TT' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'TGGCA' (5 nucleotides at position 105 to 109 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 91 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) ttcggagacgatatatctggagacagtgttacttggaactggatcaggcagTTcccccagggaagGgggcttgagtggctcgggcgtatcttcacaggtctgagTGGCAtaccgactacttggcgtctgttagaggccgaatctccatggatgtcgacacgtccaagaaccacttcaccctgcagctccgctctctgactcccgacgacacggctacatatttctgtacaagaggctctctaactgggacatatccttctgaccactggggtctgggggacccccagtgaccgtctcctcacatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5908 JY8QFUQ01CQZHV productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 5909 JY8QFUQ01BXCIA unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD5-24*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARAPRTATLLDP# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5910 JY8QFUQ01A0GUH unproductive Homsap IGHV3-72*01 F 1069 98.2 218/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + tctggattaaccctcagtgaccactacatggactgggcccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5911 JY8QFUQ01DPQLN unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5912 JY8QFUQ01A4GYO No results 5913 JY8QFUQ01BA0WX No results 5914 JY8QFUQ01BUNHA No results 5915 JY8QFUQ01BBFFD unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 259 59.28 115/194 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (59,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5916 JY8QFUQ01BA86Z productive (see comment) Homsap IGHV3-11*01 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDGDADYGDLPIPFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctgaattcagtttcactgaccaccacatgagctggatccgccgggctccagggaaggggctggagtgggtgtcatacattagtcctaCagggtagtgccatattttacgcagactctgtgaaggcccgtttcaccatctctagggacaacgccaagaatttactatatctacaaatgaacagcctgagacccgaggacacggccatctattactgtgcgagagatggggacgcggactacggtgacttgcccatccctttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 5917 JY8QFUQ01BVCVS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5918 JY8QFUQ01BLMSE No results 5919 JY8QFUQ01BJ6Y5 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); tcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattgggaaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcgGgacacggctgtgtattattgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5920 JY8QFUQ01BU1B8 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5921 JY8QFUQ01DV5O6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagcaactatgccatgaactgggtccgccagggttccagggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5922 JY8QFUQ01DTPYP unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 718 80.18 178/222 nt 79.73 177/222 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.37.X] null + Rearranged sequence but no junction found Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaacacgttgtatctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5923 JY8QFUQ01A9BT1 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca 5924 JY8QFUQ01CB275 productive (see comment) Homsap IGHV2-5*02 F 1165 97.94 238/243 nt 97.53 237/243 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.16.38.11] CAHRRIRFGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 5925 JY8QFUQ01DLCHK No results 5926 JY8QFUQ01AYBH3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgg 5927 JY8QFUQ01A98PX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5928 JY8QFUQ01BBLIL productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'AGG' (3 nucleotides at position 74 to 76 in the user submitted sequence), (do not cause frameshift); ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctgggagtgggtcAGGccaagcataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt 5929 JY8QFUQ01DH8HE productive (see comment) Homsap IGHV3-48*02 F 868 88.89 192/216 nt 87.04 188/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASGGVTEAHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tctggattcagctccagtgaatataccatgaactgGggtccgccaggctccagggGAagggggctggagtgGggtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaGggggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgggtgtttattactgcgcgagcggaggggtgacagaggctcactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5930 JY8QFUQ01C4FJ1 No results 5931 JY8QFUQ01BMUI4 No results 5932 JY8QFUQ01BK9M6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 5933 JY8QFUQ01B9DTH No results 5934 JY8QFUQ01DB2CL unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5935 JY8QFUQ01C966Y productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGYW in-frame + ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5936 JY8QFUQ01ATBFG unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 293 89.04 65/73 nt 8 X X 8.X.X [1.15.X.X] null + No rearrangement found ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtc 5937 JY8QFUQ01CZFFV No results 5938 JY8QFUQ01C5NFT productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5939 JY8QFUQ01C3FY7 productive Homsap IGHV3-48*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaangtggtcgtcgcatgcctggtccagggcttcttcccc 5940 JY8QFUQ01CCRR3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 5941 JY8QFUQ01AOQZO productive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*03 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARERSASMGAARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 99 to 101 in the user submitted sequence), (do not cause frameshift); tctctggtggccccatcggcagtggtgcctactactggacctggatccggcagcccgccgggaagggattggagtggctcgggcgtgtttatagtggtGGGgggatcatcaattacagtccctccctcaagagtcgaatcaccatgtcgatagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttatattactgtgcgagagaacgtagtgcctcgatgggcgctgcgagagaacttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5942 JY8QFUQ01BSBQN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 5943 JY8QFUQ01A4X69 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5944 JY8QFUQ01A1CLZ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 71 of V-REGION: 'CA' (2 nucleotides at position 123 to 124 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtcccCAtcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5945 JY8QFUQ01A26P2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 5946 JY8QFUQ01CA9TH unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5947 JY8QFUQ01CZI41 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5948 JY8QFUQ01C8531 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [2.17.38.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) gcctccggattcaccttagtagttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5949 JY8QFUQ01B4L0R productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - cctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5950 JY8QFUQ01BFW88 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5951 JY8QFUQ01B7Z4J unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRRGMVAGRYD#FDIW out-of-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgctttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5952 JY8QFUQ01DDD2K productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1016 97.21 209/215 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [0.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame - tggagtacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5953 JY8QFUQ01BERKI productive Homsap IGHV3-72*01 F 921 90.58 202/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5954 JY8QFUQ01BNF0N unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 5955 JY8QFUQ01BDD24 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARGKMVSTGMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcagctactggatgcactgggtccgccaagctccaggggaggggctggtgtgggtcgctcggatcaaaagtgatgggagtagcacaagctacgcgggctccgtgaggcgccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagcctgaggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 5956 JY8QFUQ01AR5RU unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5957 JY8QFUQ01A5935 productive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + tctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatcccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccc 5958 JY8QFUQ01AV6PF productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5959 JY8QFUQ01CF2PW unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*02 F 3 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGLTCT#FDYW out-of-frame - stop codons cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcgggacttacttgtactatttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5960 JY8QFUQ01BXZYZ productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag 5961 JY8QFUQ01B3GE2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5962 JY8QFUQ01DXE4S unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARADNYDSLGLKFDP# out-of-frame + tctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcattgcctgcctggtccagggcttcttcccc 5963 JY8QFUQ01AJNP6 No results 5964 JY8QFUQ01AS47P unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 804 86.45 185/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CGTSSRAWGADAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggcccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5965 JY8QFUQ01CZ4CX No results 5966 JY8QFUQ01BLB0H productive (see comment) Homsap IGHV4-61*02 F (see comment) 590 74.77 163/218 nt 73.85 161/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [1.16.38.11] CARECSNSKVGPRALDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (74,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagccgccgggaagggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctataAtttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattcctggggcccgggaagtctggtcaccgtatcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5967 JY8QFUQ01BESQ8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [2.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5968 JY8QFUQ01AH819 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 152 94.12 32/34 nt 91.18 31/34 nt 7 X X 7.X.X [1.2.X.X] null - No rearrangement found in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcaacttgccatgacct 5969 JY8QFUQ01CFXXJ No results 5970 JY8QFUQ01AQTOB No results 5971 JY8QFUQ01B3C3I No results 5972 JY8QFUQ01BWSCG No results 5973 JY8QFUQ01DOWAN No results 5974 JY8QFUQ01C6KQ4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 976 94.91 205/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.37.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtgttaatggtgatCgggggtaggacagcctacgcggactccgtgaagggccgatcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5975 JY8QFUQ01CM68L productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5976 JY8QFUQ01BFIW3 unknown (see comment) Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F 88 51.91 68/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ttctggattcacctttggtgactatgctatgagctggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 5977 JY8QFUQ01CJ8XP unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARAYSGPGPYYFD#IG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattgggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 5978 JY8QFUQ01CZS6L No results 5979 JY8QFUQ01CHLUK unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKGPRRDGSLQQCDMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggacccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5980 JY8QFUQ01CHJGG No results 5981 JY8QFUQ01CG9T4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 3 8 8 12 8.8.12 [1.17.38.11] CATGARGLGASDYW in-frame - Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggaatcacctttagcgcctatgacatgacctgggtccgccagactccagggaagggtctggagtgggtctcatccattggttcatttggtgatgacacgcactacttagactccgtgaggggccggttcaccatctccagagacaattccaacgacacgatgtatctgcaaatgctcagcctgagagtcgaggatacggccacttattactgtgcgacaggggcacgggggctcggtgcgagtgactactggggccagggaacacaggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 5982 JY8QFUQ01AKHQ3 No results 5983 JY8QFUQ01DTA3Y No results 5984 JY8QFUQ01AS13P productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + ctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5985 JY8QFUQ01CFVCE unproductive Homsap IGHV4-39*02 F (see comment) 906 92.42 195/211 nt 91.94 194/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 10 5 X 10.5.X [1.16.38.11] CARPPHGSYCP#FDYW out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (5 AA in JY8QFUQ01CFVCE ; 7 AA in Homsap_IGHV4-39*02) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 55 of V-REGION: 9 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggtgtctccatcagcagtggtcgttactactggggctggatccgccagcccccagggaaggggctggagtggattggacttagtgggagctccaacctcaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccacttctccttgaaactcaactctgtgaccgccacagacacggctgtatattactgtgctagacccccccatgggagttactgcccccttcgactactggggccagggaatcctggtgaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 5986 JY8QFUQ01CLW7C productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5987 JY8QFUQ01DCXWB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 869 88.99 194/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CTRELRMAAARDGVDIW in-frame - ctctgggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggccaaggcacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 5988 JY8QFUQ01A3O34 No results 5989 JY8QFUQ01CG0B3 No results 5990 JY8QFUQ01CC481 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 904 91.2 197/216 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame - tccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 5991 JY8QFUQ01A6DQI No results 5992 JY8QFUQ01CO7ZE productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 5993 JY8QFUQ01CPG09 No results 5994 JY8QFUQ01DOMLT productive (see comment) Homsap IGHV3-7*03 F 573 90.65 126/139 nt 89.93 125/139 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 X 19 8.X.19 [1.15.22.11] CARDRYSSDSSYYMPNWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 78 nucleotides (from position 74 in the user submitted sequence), (do not cause frameshift) ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5995 JY8QFUQ01C6HJC No results 5996 JY8QFUQ01ACI1B unknown (see comment) Homsap IGHV3-64*02 F (see comment) 630 76.85 166/216 nt 8 8 X 8.8.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (76,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 5997 JY8QFUQ01B2V0H unproductive Homsap IGHV1-2*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*01 F 109 68.75 33/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [0.16.38.11] CARDGISMTLVRGVRPXDY# out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctggatacaccttcatcggccattatatacattgggtgcgacaggccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttngactactggggccaggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 5998 JY8QFUQ01C4GHR productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 90.91 200/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgataatttctactggggctggatccgccagccCcccagggaagggactgcagtggattgGggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 5999 JY8QFUQ01BMVUA No results 6000 JY8QFUQ01DA5JD unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + stop codons ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgtaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 6001 JY8QFUQ01A07SP No results 6002 JY8QFUQ01APX85 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaagctccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 6003 JY8QFUQ01AG0BX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtctcccctcggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6004 JY8QFUQ01BJGET unproductive (see comment) Homsap IGHV1-18*01 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYCSTKNCFAKTDFVWGP*#YW out-of-frame + stop codons tggttacagttttaccaattatggtattagctgggcgcgacaggcccctggacaagggcttgagtggatgggatggatcagcacattcaatgatgtcacataccttgcacagaagttccagggcagagtcaccatgaccactgacacctccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtttatttttgtgcgagagacggatattgtagtacgaagaattgcttcgccaagaccgacttcgtttggggaccataaactactggggccagggatccctggtcgccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 6005 JY8QFUQ01CI94Y productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaTggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccagttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6006 JY8QFUQ01CIZXQ No results 6007 JY8QFUQ01DB6Y7 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 91 58.11 43/74 nt 8 X X 8.X.X [2.14.X.X] null - No rearrangement found gcctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6008 JY8QFUQ01AR3VS No results 6009 JY8QFUQ01CC6TQ unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 129 62.82 49/78 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6010 JY8QFUQ01DL4ZH No results 6011 JY8QFUQ01C6H8W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6012 JY8QFUQ01DW4N9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'GCTGGGA' (7 nucleotides at position 62 to 68 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggGCTGGGAgtggggtcagtctgggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6013 JY8QFUQ01DS8TN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-48*01 F 950 93.12 203/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDRITIFSYNW#FDPW out-of-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggtttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6014 JY8QFUQ01DQG0K unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 106 55.77 58/104 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6015 JY8QFUQ01BYF1A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctggggctgcctggtcaagggactacttgcccccgaaccggtgacggtgtcgtggaactc 6016 JY8QFUQ01BBG0J No results 6017 JY8QFUQ01ATBZH No results 6018 JY8QFUQ01CWLFI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6019 JY8QFUQ01BIYSS No results 6020 JY8QFUQ01CU3GV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6021 JY8QFUQ01BRNFF productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame + ctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccanccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6022 JY8QFUQ01CJRQU No results 6023 JY8QFUQ01CJ6OW No results 6024 JY8QFUQ01AM18K unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 6025 JY8QFUQ01BM4YY productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame + ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 6026 JY8QFUQ01AYKK2 No results 6027 JY8QFUQ01AJ3M6 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6028 JY8QFUQ01B401Y unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 92 90.91 20/22 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found ctctggattaaccctcagtgac 6029 JY8QFUQ01CEXWC productive Homsap IGHV3-66*02 F (see comment) 759 84.11 180/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame + Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6030 JY8QFUQ01BXTW5 productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6031 JY8QFUQ01DQWNK No results 6032 JY8QFUQ01AXYJ6 unproductive (see comment) Homsap IGHV4-39*03 F 923 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 9 7 X 9.7.X [1.17.38.11] CARSITLTVVVMND##FDVW out-of-frame - stop codons in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) tccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgccttttgatgtctggggccaagggacattggtcaccgtctccttagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6033 JY8QFUQ01B6ES1 productive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 6034 JY8QFUQ01DMIV2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6035 JY8QFUQ01BE13M No results 6036 JY8QFUQ01C30YK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgtccatagcatgaactggtccgccaggctccaggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccctctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6037 JY8QFUQ01CFSGR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); ctctggattcaccttcgGggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6038 JY8QFUQ01AVBLL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1035 97.7 212/217 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 6039 JY8QFUQ01CWSFH unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREDGFRQT##FDYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggttccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6040 JY8QFUQ01A52Y0 unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6041 JY8QFUQ01CS07U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaTggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6042 JY8QFUQ01DAU99 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame - tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6043 JY8QFUQ01CUYR1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6044 JY8QFUQ01B8DY9 No results 6045 JY8QFUQ01CO5QN productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [2.16.38.11] CAKEQEPHGHYVGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) gcgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccagcaagggctggagtggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6046 JY8QFUQ01CD20L No results 6047 JY8QFUQ01AU91D No results 6048 JY8QFUQ01BPDC6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [2.17.38.11] CAKSECRDCYPKNYLDYW in-frame - gcctctggattcacctttacctactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtggtgttggtaacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgggagccgacgacacggccgtatattactgtgcgaaatcggagtgtcgtgactgctaccctaagaactaccttgactactggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6049 JY8QFUQ01DNT81 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 7 8 12 7.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) gcctcaggatcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6050 JY8QFUQ01AL9P8 No results 6051 JY8QFUQ01CWDG3 No results 6052 JY8QFUQ01A6DSA productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6053 JY8QFUQ01C46L0 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [0.17.38.11] CARLGQLALDYW in-frame + tggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6054 JY8QFUQ01BU4ML No results 6055 JY8QFUQ01A9RMF productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 89.72 192/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6056 JY8QFUQ01DBBYU No results 6057 JY8QFUQ01CUSQF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6058 JY8QFUQ01AOAW9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 113 67.27 37/55 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctccggattcacctttagtagtttctggatgcactgggtccagggcttcttcccc 6059 JY8QFUQ01BQ6JD unproductive (see comment) Homsap IGHV3-7*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [0.17.37.11] CARVGYGYRGIYF#FDYW out-of-frame - stop codons in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 191 in the user submitted sequence), (cause frameshift) ctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagcgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttcctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6060 JY8QFUQ01CKPJN productive Homsap IGHV3-9*01 F 990 95.39 207/217 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtggatctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6061 JY8QFUQ01AZJDB unproductive Homsap IGHV3-7*01 F 1032 96.82 213/220 nt 96.36 212/220 nt Homsap IGHJ6*01 F (see comment) 148 70.97 44/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSGFTRRA#W out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggcggcgaaggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6062 JY8QFUQ01DL8G0 No results 6063 JY8QFUQ01B6Y53 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6064 JY8QFUQ01C3OQP productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F (see comment) 793 84.93 186/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 10 7 11 10.7.11 [1.17.38.11] CAGGEDPFKVRHW in-frame - Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtggctccttttctaatcatggttaccactgtagttggctccgccagttcccagggaaggacctggagtggattgcctacatctattacactgggagcaccgagtataacccgtccctcaggagtcgagttgccatatcagtggacacgtctgggaaccagtgttccctggagttgaactctgtgagtgccgcggacacggccgtctattactgtgcgggaggcgaggatcccttcaaagttcgacactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6065 JY8QFUQ01DC9NI unproductive Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6066 JY8QFUQ01ADMF5 No results 6067 JY8QFUQ01A3ATB unknown (see comment) Homsap IGHV3-13*02 F, or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-35*01 ORF 105 100.0 21/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcaccttcagtaa 6068 JY8QFUQ01BH9IY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [1.16.38.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtagtttgccatgacctggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6069 JY8QFUQ01BA4FL productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 816 85.91 189/220 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARAGGWTPYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactatgctggggccaccaacctcgcctcctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggaccccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6070 JY8QFUQ01CVRND productive (see comment) Homsap IGHV3-33*05 F (see comment) 762 83.18 183/220 nt 82.73 182/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); agcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6071 JY8QFUQ01DHLX1 No results 6072 JY8QFUQ01DG2P7 productive (see comment) Homsap IGHV1-3*01 F 956 94.81 201/212 nt 94.34 200/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 7 9 8.7.9 [0.17.38.11] CARWNNDLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6073 JY8QFUQ01A32WM productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6074 JY8QFUQ01AD2CD No results 6075 JY8QFUQ01AMAA3 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6076 JY8QFUQ01B5PFC No results 6077 JY8QFUQ01BTTXT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDDGGHMTLDV## out-of-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggcccaagggacaatggtcagcgtctctccggcctccaccaagggcccaatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccagaccggtgacggtgtgcgtggaactcag 6078 JY8QFUQ01BEU1H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6079 JY8QFUQ01A5TJ6 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccactaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 6080 JY8QFUQ01AOBK0 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 774 83.87 182/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] XVRGPF*CQLVWQ#WFDPW out-of-frame + stop codons Low V-REGION identity (83,87% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatcttcggcaactattggatgcactgggtccgccaagctcctgggaaggggctggagtgggtctcacgtatcaatggcgacggaagtcacataagttacgcggactccgtgaagggccgattcgtcatctccagagacaacgccgagaacacactatttctgcaaatgaattctctcagagccgaagatacagccttatatttttgngtgagaggcccgttttagtgtcagttggtatggcaggctggttcgacccctggggccagggaacgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6081 JY8QFUQ01CGZGV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6082 JY8QFUQ01CZZJS unproductive Homsap IGHV3-7*01 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.37.11] CAGAEAGL#DYW out-of-frame + in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 189 in the user submitted sequence), (cause frameshift) tctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga 6083 JY8QFUQ01BKOO0 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 962 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-15*01 F 2 8 7 29 8.7.29 [1.17.38.11] CARVWATEERNCRGATCYYPPMGHFNGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctatggtgggtcttttagtggttactactggagttggatacgccagtccccagggaaGggggctggagtggattgGgggaaatcaatcatagtggaagcaccaacttcaacccgtccctcaagagtcgagtcaccatttcagtagacaggtccaagaaccagttgtccctgaggctgacctctgtgaccgccgcggacacggctatgtattactgtgcgagagtttgggcgaccgaagagcgaaattgtcgtggtgcgacctgctactatccccccatgggccacttcaacggtatggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6084 JY8QFUQ01BA26E No results 6085 JY8QFUQ01A4I3A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ccctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6086 JY8QFUQ01BHQM5 No results 6087 JY8QFUQ01AJOAH productive (see comment) Homsap IGHV3-7*01 F 996 95.0 209/220 nt 94.09 207/220 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDPYNGGGYGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); agcctctggattGcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtAgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6088 JY8QFUQ01C55YS productive (see comment) Homsap IGHV3-69-1*01 P (see comment) 365 76.56 98/128 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-8*01 F 2 X 5 17 X.5.17 [X.X.38.11] CVRDVSLYSNDGYDAFDIW in-frame - however the closest V is a pseudogene Low V-REGION identity (76,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttttagtaacttttggatgagttggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagagacgtctccctttatagtaatgatggatatgatgcttttgatatttggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6089 JY8QFUQ01AZGM1 productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGKMVSTGMDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattcacgtttagtgactactacatgacctggattcgtcaggctccagggaagggcctggagtgggttacatatattagtagtagtggtggtaacacacattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6090 JY8QFUQ01DMROR unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGL*QWL##DFDCW out-of-frame + stop codons ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6091 JY8QFUQ01B4ZPZ productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 X 5 16 X.5.16 [X.X.38.11] CAKVMWGVTGPIDPFDYW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 6092 JY8QFUQ01BFEGM unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [2.17.38.11] CARGVGQQLPP*#W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gtctctcgtgcctccatcaataCctttttactggagctggatccggcagcccccagggaagggactggagtggattggatatatctatgatagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggggtggggcagcaactgcccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6093 JY8QFUQ01BNQG3 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDIGVHMWTIDYW in-frame + ctctggattcacgtttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaaagatattggggtacacatgtggaccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6094 JY8QFUQ01BDAEH No results 6095 JY8QFUQ01BDP4Y productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6096 JY8QFUQ01A4IHP No results 6097 JY8QFUQ01BOMRP productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*01 F 402 92.55 87/94 nt 91.49 86/94 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 X X 16 X.X.16 [X.X.31.11] CAKDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ctctggattcaccatctccagagacaattccaagaacacggtgtatctgcAaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 6098 JY8QFUQ01AG59I No results 6099 JY8QFUQ01DFIB5 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6100 JY8QFUQ01BFS0C unknown (see comment) Homsap IGHV3-52*01 P, or Homsap IGHV3-52*02 P or Homsap IGHV3-52*03 P or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 121 82.86 29/35 nt 8 X X 8.X.X [1.2.X.X] null - No rearrangement found gtctggatttaccttcagtaagttctggatgcatt 6101 JY8QFUQ01DMF0A productive (see comment) Homsap IGHV4-55*03 P (see comment) 608 75.58 164/217 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARESRNSFGGPTGLDSW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DMF0A ; 9 AA in Homsap_IGHV4-55*03), and low V-REGION identity (75,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctgttgacgccataagcgacctcggttatttctgggcctgggtccgccagcccgccgcgaagggactggagtggatcggacatgcccttggtgatggatataccgaatacaaccccgccctagagagtcgaatcaccgtgtcagtggacaagtccaagaaccagttttccctgacgttggagtccgtgaccgccgcagacacggccacttatttctgtgcgagggaaagtcggaattcatttggcgggccgacaggccttgattcctggggccagggaattgtggtcatcgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggacgtgtcctcgcctgcctggtccagggcttctccc 6102 JY8QFUQ01C1LQM productive Homsap IGHV3-7*01 F 934 93.43 199/213 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt 8 8 9 8.8.9 [X.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6103 JY8QFUQ01CA2QL No results 6104 JY8QFUQ01AXYNU productive (see comment) Homsap IGHV3-11*01 F 919 93.33 196/210 nt 92.86 195/210 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [X.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 91 in the user submitted sequence), (do not cause frameshift) ggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6105 JY8QFUQ01BKNCA No results 6106 JY8QFUQ01DLZ1V productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 6107 JY8QFUQ01C0X1D No results 6108 JY8QFUQ01ALZG8 No results 6109 JY8QFUQ01BH1Z3 No results 6110 JY8QFUQ01DM1O4 No results 6111 JY8QFUQ01ARMLR productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcatagccgccctgggctgcctagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6112 JY8QFUQ01AIFNF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6113 JY8QFUQ01C5RLP No results 6114 JY8QFUQ01A2K1H unproductive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CLAEVGGRQFDN## out-of-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccaggggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6115 JY8QFUQ01C65NA No results 6116 JY8QFUQ01AHFMC No results 6117 JY8QFUQ01CPYST productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggc 6118 JY8QFUQ01A1GYW productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 6119 JY8QFUQ01DJRFW No results 6120 JY8QFUQ01AY94E productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaaccCcgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6121 JY8QFUQ01CUCST No results 6122 JY8QFUQ01DW81Y productive (see comment) Homsap IGHV4-59*02 F 928 93.36 197/211 nt 92.42 195/211 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-16*02 F 3 8 7 16 8.7.16 [0.16.38.11] CASAIMITFGGVIVMTTG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'AAC' (3 nucleotides at position 23 to 25 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) ctggattcaccgtcaataggaaAACgtacatgagctggatccggcagacccccaggaagggactgagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgnccgctgcggacacggccgtgtattactgtgcctcagccattatgattacgtttgggggagttatcgttatgactactggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6123 JY8QFUQ01C2SCV unproductive (see comment) Homsap IGHV3-48*04 F 936 92.63 201/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKCYQP*IL*PL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctcgagagacaacgccaagaacgccctatatctgcaaatgaacagtctgagagttgaggacacggccttgtatttctgtgcaaaatgctaccagccgtgaatactttgaccactgggggccagggaaccctaatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa 6124 JY8QFUQ01BMJTK productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6125 JY8QFUQ01B7HNH productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6126 JY8QFUQ01BZWPP unproductive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARVIPGRGK##AFDVW out-of-frame + stop codons ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggcaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6127 JY8QFUQ01CU8BS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.16.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 6128 JY8QFUQ01BCV0I productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 649 93.88 138/147 nt 93.2 137/147 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [2.8.31.11] CARRDVGLHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 55 in the user submitted sequence), (do not cause frameshift) ggttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 6129 JY8QFUQ01DQEAT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.03 181/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6130 JY8QFUQ01BI9NH unproductive (see comment) Homsap IGHV4-34*03 F (see comment) 574 77.32 150/194 nt 76.8 149/194 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 7 14 8.7.14 [1.17.31.11] CTTRPRGWEPLGLDYW in-frame - stop codons Low V-REGION identity (77,32% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 77 of V-REGION: 20 nucleotides (from position 133 in the user submitted sequence), (cause frameshift) tcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagatgattcaaaaaacttggtgtttctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtaccacacggccccgggggtgggaaccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6131 JY8QFUQ01CSVJ1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctcggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6132 JY8QFUQ01CUU0C productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 859 90.82 188/207 nt 90.34 187/207 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [2.17.38.11] CARHPKSNVEGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 16 in the user submitted sequence), (do not cause frameshift) gtctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6133 JY8QFUQ01BGDO5 unproductive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaaggggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6134 JY8QFUQ01A2R9O No results 6135 JY8QFUQ01BK8ZG unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 250 58.76 114/194 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (58,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6136 JY8QFUQ01BA7BP productive (see comment) Homsap IGHV3-7*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 7 9 8.7.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggcgtggagtgggtgccacataagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttccccc 6137 JY8QFUQ01CQRBP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6138 JY8QFUQ01A4PTA unproductive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQW# out-of-frame + stop codons in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtgggggcccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6139 JY8QFUQ01DL9AO productive Homsap IGHV3-48*01 F 846 88.02 191/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggattcacttttgatgactctgccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcttggaactcag 6140 JY8QFUQ01BYCP5 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6141 JY8QFUQ01DQ18I productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6142 JY8QFUQ01DFHQO No results 6143 JY8QFUQ01ALCSF No results 6144 JY8QFUQ01BN0FB No results 6145 JY8QFUQ01CPQ0G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6146 JY8QFUQ01CYXGO unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGGW*RRP*LLG in-frame + stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggCccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgccctgcctggtccagggcttcttcccccc 6147 JY8QFUQ01BTSDV unknown (see comment) Homsap IGHV3-72*01 F 238 94.34 50/53 nt 8 X X 8.X.X [1.8.X.X] null - No rearrangement found cctctggcttcatcttcagtgaccactatatggactgggtccgccaggctcca 6148 JY8QFUQ01CGGC1 No results 6149 JY8QFUQ01DVZZK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggcttcttcccccga 6150 JY8QFUQ01BPF6G No results 6151 JY8QFUQ01AZM4V No results 6152 JY8QFUQ01BJJ7G productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6153 JY8QFUQ01BSD92 productive (see comment) Homsap IGHV4-61*02 F 986 94.95 207/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-10*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARGSGTYYNPMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'ACTG' (4 nucleotides at position 34 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tttctggtgcctccatcagcagtggtagttactACTGgggactggatccggcagcccgccgggaagggactggagtggattgggcgtatccataccagtgggggAcaccaactacaccccctccctcaagagtcgactcaccatatcagtagacgcgtccaagaaccaggtctccctgaggctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggttcggggacttattacaaccctatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6154 JY8QFUQ01ATVRQ unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactGactggggctggatccgccagcccccagggaaggggctggagtggattgggagtaCtctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgaccggtgtcgtggaactcag 6155 JY8QFUQ01A38FQ unknown (see comment) Homsap IGHV4-61*02 F (see comment) 702 80.65 175/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6156 JY8QFUQ01CI1J0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6157 JY8QFUQ01AHUB9 unproductive Homsap IGHV3-7*01 F 1047 99.07 212/214 nt 98.13 210/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.37.11] CARDKYYDFWSDHYPGG#YGMDVW out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 199 in the user submitted sequence), (cause frameshift) tctggattcaccGtttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtggtgggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacggctgtgtattactgtgcgagagacaagtattacgatttttggagtgatcattacccagggggggtacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6158 JY8QFUQ01BNJ81 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 6159 JY8QFUQ01BS6C5 unproductive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F or Homsap IGHV4-61*02 F 596 86.71 137/158 nt 85.44 135/158 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt X 6 X X.6.X [X.9.37.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 43 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 98 of V-REGION: 1 nucleotides (from position 141 in the user submitted sequence), (cause frameshift) gggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagaacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaaatttgactttctgggggccagggaacccctggtcacccgtctccctagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6160 JY8QFUQ01CHV4Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6161 JY8QFUQ01BNA9I No results 6162 JY8QFUQ01ADD1O productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 6163 JY8QFUQ01BDTYM productive (see comment) Homsap IGHV3-48*01 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6164 JY8QFUQ01DBCR2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 348 86.02 80/93 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found tctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 6165 JY8QFUQ01DMUXO productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 924 91.36 201/220 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 6166 JY8QFUQ01A9I9K No results 6167 JY8QFUQ01BDH99 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaAaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6168 JY8QFUQ01DAW4B No results 6169 JY8QFUQ01B61ES No results 6170 JY8QFUQ01BOAMW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6171 JY8QFUQ01BKT0I No results 6172 JY8QFUQ01DGTXX unproductive (see comment) Homsap IGHV4-39*03 F 928 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-22*01 F 1 9 7 X 9.7.X [1.17.38.11] CARSITLTVVVMND##FDVW out-of-frame - stop codons in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgccttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6173 JY8QFUQ01BS4F8 unproductive (see comment) Homsap IGHV3-7*01 F 936 92.63 201/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt 8 8 X 8.8.X [1.17.38.11] CATSP*RLLTDDGGLLG (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 51 of V-REGION: 'GA' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggaggggcgtggaGAgtgggtggccaaTcataaagtcagatggGaagtgaCaaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctccccctagcgacttttgacagacgatggggggttactgggggcccaaggggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtctttccccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 6174 JY8QFUQ01AHXIB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6175 JY8QFUQ01CD6S8 No results 6176 JY8QFUQ01B5QXF productive Homsap IGHV3-48*01 F 1070 99.53 214/215 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [0.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - ctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6177 JY8QFUQ01BTMEZ No results 6178 JY8QFUQ01AM3RG No results 6179 JY8QFUQ01BDUFZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDATAISSGYYHRLDYW in-frame + ctctggcttcacctttgaaaattatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtcgcagcaatcagtcttagtggtggaagtacatacttcgcggactccgtcaagggccggttctccatcgcccgggacaactccaaggacaccctgtatcttcacatggacagcctgagagccggggatacggccacatattattgtgcgaaagacgcaactgcgattagtagcggttattatcaccgacttgactactggggccagggtaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6180 JY8QFUQ01CBST2 productive Homsap IGHV3-11*01 F 929 91.4 202/221 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [2.17.38.11] CARVKYSSSWSSILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cagcctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcattcattagtagtcctggtatcaggagtttctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6181 JY8QFUQ01AG9UH unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-16*02 F 2 8 8 X 8.8.X [0.17.38.11] CARGDLP#YIDYW out-of-frame - tggatacatcttcaccagctactttatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaatagtcaaccctagtggagctggcacaacttacgcacagaagttccagggcagagtcaccatgaccagcgacacgtccacgaccacagtctacatggagctgagcagcctgagatccgacgacacggccatatattactgtgcgagaggcgatctccccactacattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6182 JY8QFUQ01CIA8P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6183 JY8QFUQ01BL0M4 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 905 90.83 198/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 1 9 7 20 9.7.20 [1.17.38.11] CVRDGRRTYNSGWYSLAAFDIW in-frame + tctctggtgtctccatcagcagtggtaactggtggagctgggtccgccagcccccagggaaggggctggaatggattggagaaatctcttatagtgggaccaccaagtacaaccggtccctcaagagtcgagtcaccatatcactagacacgtccaaaaaccatttctccctgcagctgacttctgtgaccgccgcggacacggctgtctattattgtgtgagagatggtcgccggacctataacagtggctggtattcgttagctgcttttgatatctggggccaggggacagtggtcaccgtctcttccgcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 6184 JY8QFUQ01CX0E8 No results 6185 JY8QFUQ01CFBH9 productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-33*03 F (see comment) 376 78.86 97/123 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 X 3 17 X.3.17 [X.X.38.11] CAKDTITMGGDVAPLFDYW in-frame - Low V-REGION identity (78,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release acctctggattcacctttaactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6186 JY8QFUQ01A5NH7 No results 6187 JY8QFUQ01DW085 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6188 JY8QFUQ01AVQDO No results 6189 JY8QFUQ01BGW7G No results 6190 JY8QFUQ01ABYMU No results 6191 JY8QFUQ01AGE1J No results 6192 JY8QFUQ01BJEZU No results 6193 JY8QFUQ01DJ2RD unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccaagggaaccctggtcaccgtctcctcagcctccaccaagggcccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6194 JY8QFUQ01A7RY0 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*03 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CSKTHLGE#DYW out-of-frame - cctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaagacacatttgggcgagaagactactgggccagggaggccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 6195 JY8QFUQ01A28YA No results 6196 JY8QFUQ01CR1W7 No results 6197 JY8QFUQ01BGKCU No results 6198 JY8QFUQ01A97AT No results 6199 JY8QFUQ01DI5MR productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD5-18*01 F 3 10 7 14 10.7.14 [2.16.37.11] CARSQSRYSWGDFLHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagcagtactagttactactggggctggatccgccagccccagggagggggctggagtggattggaagcatctattatagtgggagcacctcctacaacccgtcctcgagagtcgaatcaccatgtccgtagacatgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtttatttctgtgcgcggtcccagagtagatacagttggggtgacttcttacactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6200 JY8QFUQ01DBT6J unproductive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGHFR**WLFQP#LDHW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttcgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccaagcatggaacgtgtcgtcgcatgcctggtccagggcttcttcccccag 6201 JY8QFUQ01BOIP3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6202 JY8QFUQ01DQZFP No results 6203 JY8QFUQ01DBIOF productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + ctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6204 JY8QFUQ01CI5CF No results 6205 JY8QFUQ01DH145 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6206 JY8QFUQ01CBO42 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6207 JY8QFUQ01DI164 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 494 96.23 102/106 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatact 6208 JY8QFUQ01CLEAH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGEFYYETSGRRGFDYW in-frame - ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6209 JY8QFUQ01ABF8G productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.69 196/221 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame + tctctggtgactccattggtagcagtgcctactactggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6210 JY8QFUQ01AD6NQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 407 79.23 103/130 nt 77.69 101/130 nt 7 6 X 7.6.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (79,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) tctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6211 JY8QFUQ01CUO32 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6212 JY8QFUQ01C2LVB No results 6213 JY8QFUQ01CNBY9 unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 408 80.65 100/124 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtcccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6214 JY8QFUQ01CC175 No results 6215 JY8QFUQ01AVOJA productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6216 JY8QFUQ01BH7IW productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.37.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 98 of V-REGION: 1 nucleotides (from position 197 in the user submitted sequence), (cause frameshift) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagcagcgagacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6217 JY8QFUQ01CWJN1 No results 6218 JY8QFUQ01AQ36T productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6219 JY8QFUQ01DHC55 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6220 JY8QFUQ01AFRTD No results 6221 JY8QFUQ01B5QM6 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 6222 JY8QFUQ01AROL9 unknown (see comment) Homsap IGHV3-23*05 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6223 JY8QFUQ01C00ZK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6224 JY8QFUQ01BU9ER No results 6225 JY8QFUQ01CWZ8I No results 6226 JY8QFUQ01C7M0Q productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccCctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6227 JY8QFUQ01DGOJK No results 6228 JY8QFUQ01DLDT4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); gcctctggattcaccCTtttaacaactaCggccatgtcctgggtccgccaggctccagggaaAggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaTggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtataAtttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6229 JY8QFUQ01DECPM productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 817 87.32 186/213 nt 86.85 185/213 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.37.11] CVGVGVGSSVSFQYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) ctctggattcactgtcaataacaactacatgggttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacacttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6230 JY8QFUQ01CW5NA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctccgtcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6231 JY8QFUQ01AY4JM productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6232 JY8QFUQ01DT7AW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 904 91.2 197/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctcgattcacctttagcagctatgtcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6233 JY8QFUQ01A5QD0 No results 6234 JY8QFUQ01DMASI unproductive (see comment) Homsap IGHV3-48*03 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaacctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6235 JY8QFUQ01BAV7R productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6236 JY8QFUQ01B95YA No results 6237 JY8QFUQ01B8PU0 productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame + tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6238 JY8QFUQ01CDPWD productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6239 JY8QFUQ01CNBDG No results 6240 JY8QFUQ01CSQN6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1033 98.59 210/213 nt 98.12 209/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.37.11] CASANYDYVWGSYRYDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 198 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcagtccttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6241 JY8QFUQ01B4RF9 No results 6242 JY8QFUQ01CM8P9 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + ctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6243 JY8QFUQ01BLJ6R unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 595 82.66 143/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (82,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgc 6244 JY8QFUQ01A3F5T productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6245 JY8QFUQ01CDDRR productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1091 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgagagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6246 JY8QFUQ01CZ7EK No results 6247 JY8QFUQ01BLBZG No results 6248 JY8QFUQ01BS864 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 880 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6249 JY8QFUQ01AUUYM unknown (see comment) Homsap IGHV3-72*02 F 129 53.46 85/159 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 6250 JY8QFUQ01BX3EL No results 6251 JY8QFUQ01CXFTB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6252 JY8QFUQ01ALNPO No results 6253 JY8QFUQ01CTNRY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); agcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttaCctggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccctgaaccggtgacggtgtcgtggaactcag 6254 JY8QFUQ01AHZXQ unproductive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDVTSESHFFALDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcatttcttcgctttggacgtctgggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6255 JY8QFUQ01COSNV No results 6256 JY8QFUQ01CFWG2 No results 6257 JY8QFUQ01CBKG2 productive (see comment) Homsap IGHV3-23*05 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 6258 JY8QFUQ01BMXML No results 6259 JY8QFUQ01BO55X unproductive (see comment) Homsap IGHV3-72*01 F 523 86.96 120/138 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-6*01 F 2 X 8 X X.8.X [X.X.38.11] CPREL*EVDFAR#W out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcccagttagaccacagactacgccgcgcctgtgaaaggcagattcaccatttcaagagatgattcaaagtaatcactgtatctacaaatgaacagcctgaaaaccgaggacacggtcgtgtattagtgtcctagagaattataggaggtcgattttgctcgttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6260 JY8QFUQ01BNU7I productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 6261 JY8QFUQ01CZ5K0 unknown (see comment) Homsap IGHV4-61*02 F (see comment) 509 77.33 133/172 nt 76.74 132/172 nt 10 7 X 10.7.X [1.17.22.X] null - No rearrangement found Low V-REGION identity (77,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'AG' (2 nucleotides at position 106 to 107 in the user submitted sequence), (cause frameshift); gtctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacAGtgatcacaaccctccctgcggggggcgagtcgccatgtcactggacacgtccagggcttcttcccca 6262 JY8QFUQ01BWJF3 No results 6263 JY8QFUQ01CLDYZ No results 6264 JY8QFUQ01AWTQR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 890 90.7 195/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [1.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01AWTQR ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 6265 JY8QFUQ01AGMA8 unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 6266 JY8QFUQ01AA0SS No results 6267 JY8QFUQ01C6HW4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ3*02 F 250 100.0 50/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame - cctctggattcacctttagcagctatgccatgggctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtgggagtggtcggagcacatactacgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccatatattattgtgtgaaaaggttggaaggagtggctgatgatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6268 JY8QFUQ01BRQL0 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtgcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccccga 6269 JY8QFUQ01BK2CH productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 6270 JY8QFUQ01B9AGF unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDDKWAFDY# out-of-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactgggccagggaaccctggtcgtcgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg 6271 JY8QFUQ01CO0WU No results 6272 JY8QFUQ01DNMM3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 6273 JY8QFUQ01DIYR4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKIV*YTR*G#AFDMW out-of-frame - stop codons tctggattcaccttcagaaccaatgccatgaactgggtccgccaggctccagggaaggggctggagtggatctcagttattaatggtcccggtgatatcacatactacgcagactccgtgaagggccggttcaccatgtcccgagacaattccaaggacacgttgtatttgcaaatgatcagcctgagaggcgaggacacggccatatattactgtgcaaagatcgtatgatacacacgatgaggggagcttttgatatgtggggccgagggacaatggtcaccgtctcttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6274 JY8QFUQ01AM0AD productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.37.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 113 in the user submitted sequence), (cause frameshift) agtctctggattcaccgtcaatagGAaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6275 JY8QFUQ01B6Y0Z unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 135 100.0 27/27 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tctccggggacagtgtctctagcaaca 6276 JY8QFUQ01AHK2I productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6277 JY8QFUQ01ATP5E No results 6278 JY8QFUQ01BT2TZ No results 6279 JY8QFUQ01CQ3YF unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 216 97.78 44/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcaccttcagtagctactggatgcactgggtccccca 6280 JY8QFUQ01CXLJP No results 6281 JY8QFUQ01A3J3K No results 6282 JY8QFUQ01DQSTN No results 6283 JY8QFUQ01AQJZF productive Homsap IGHV3-7*01 F 852 87.73 193/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctctgggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcgagatggaactgagagtcattatgtggactctgtgaagggccgattcatcatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6284 JY8QFUQ01B0SVG No results 6285 JY8QFUQ01BOH7B productive Homsap IGHV1-8*01 F 844 88.26 188/213 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [X.17.38.11] CARVGETHYHYGVDVW in-frame + ggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgagacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6286 JY8QFUQ01C4IX9 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6287 JY8QFUQ01BBNT0 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 867 87.44 195/223 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CTADVPSPLAQNDF# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 6288 JY8QFUQ01C84Q1 No results 6289 JY8QFUQ01AFZCG productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6290 JY8QFUQ01AHS1H unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6291 JY8QFUQ01DK4RM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag 6292 JY8QFUQ01C470B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CVRESFSRTIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggattcatctttagcagatatgccatgagttgggtccgccagcctccagggaaggggctggagtgggtctcagccatagttggtagtggtggtggtgcatactacgcagactccgtgaagggccggttcaccgtctccagagacaatgatgaaaacaccctgtctctgcaaatgagcagcctgagagtcgaagacacggccatgtattattgtgtgagagaatcatttagcaggacgattgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6293 JY8QFUQ01BKNBD No results 6294 JY8QFUQ01CQML7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 169 82.0 41/50 nt Homsap IGHD4-17*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDRLNGDYTFGAFDLW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaacggtgactacacattcggcgcatttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 6295 JY8QFUQ01CWB3S No results 6296 JY8QFUQ01BEJUJ productive Homsap IGHV3-7*01 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSAYFSTGYW in-frame - gcctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6297 JY8QFUQ01B8977 No results 6298 JY8QFUQ01DU32V unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 262 57.53 126/219 nt 57.08 125/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (57,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'CT' (2 nucleotides at position 37 to 38 in the user submitted sequence), (cause frameshift); gggtctggatacatctttaatatccactggatcgccCTggggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6299 JY8QFUQ01B8UEP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6300 JY8QFUQ01CKVS0 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 228 57.44 112/195 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (57,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcaatagttactggatgcactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6301 JY8QFUQ01A6W08 productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 176 86.96 40/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 6302 JY8QFUQ01B31FY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6303 JY8QFUQ01DH69T productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6304 JY8QFUQ01BGFAG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [2.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6305 JY8QFUQ01CCY1K productive (see comment) Homsap IGHV3-72*01 F 1053 96.46 218/226 nt 96.02 217/226 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 10 13 8.10.13 [2.17.38.11] CVRGLHSNYYGMDVR in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaAaggggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcaggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6306 JY8QFUQ01B8Y2R productive Homsap IGHV4-39*02 F 947 92.31 204/221 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD5-18*01 F 1 10 7 14 10.7.14 [1.17.38.11] CARGMDTTRVARLDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggcagtttactattgtgcgaggggaatggatacaactagggtcgcccgtttggatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 6307 JY8QFUQ01ARZ0L unproductive Homsap IGHV3-48*03 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [2.17.38.11] CARESWWSGFM#WYDPW out-of-frame - gcctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggctttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6308 JY8QFUQ01C979I productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctctggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6309 JY8QFUQ01DXBXM No results 6310 JY8QFUQ01CRX09 No results 6311 JY8QFUQ01DJLI0 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame - ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6312 JY8QFUQ01DO3JY productive (see comment) Homsap IGHV4-39*02 F 947 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtactaataattactactCgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6313 JY8QFUQ01DLZKB productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6314 JY8QFUQ01A7CMG productive Homsap IGHV1-3*01 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacatattcaccgacttttatatacactgggtgcgacaggcccctggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccg 6315 JY8QFUQ01AH1M0 No results 6316 JY8QFUQ01DEZMP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 6317 JY8QFUQ01A4W5D productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 921 92.52 198/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6318 JY8QFUQ01BXFLS unproductive Homsap IGHV4-61*02 F 879 89.09 196/220 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 1 10 7 X 10.7.X [1.17.38.11] CSRSLPRGYYYYGVGI# out-of-frame + ctctggtggctccatcggtagtggaaattattactggagctggattcgacagaccgccggaaagggactggagtggattgggcggatatatagtactgggagcaccgactacaacccctccctcaacagtcgagtcaccttgtccatggacacgtccaagaaccagttctccctgaaactgggctctgtgaccgccgcagacacggccgtctattactgttccaggtctcttccacgaggctactactactatggtgtgggcatctgggcccagggaccacggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccc 6319 JY8QFUQ01BW0IZ productive (see comment) Homsap IGHV3-33*05 F (see comment) 742 82.87 179/216 nt 81.94 177/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6320 JY8QFUQ01DJV69 productive Homsap IGHV3-48*04 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CASFSGWEHEYW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtttcctcgattattagtagtggtagcaatatatacgacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagcttcagtgggtgggagcatgagtactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa 6321 JY8QFUQ01BQY7O No results 6322 JY8QFUQ01B22ET No results 6323 JY8QFUQ01BZ8IQ unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1030 97.69 211/216 nt Homsap IGHJ4*03 F (see comment) 132 75.0 36/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARPYCGGDCHNRGAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctgggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccctaaggtcttcccgctgagctcgacagcaccccccgaagatgggaacgtggtcgtcncatgcctggtccagggcttcttccc 6324 JY8QFUQ01BICWN No results 6325 JY8QFUQ01CIJ1X No results 6326 JY8QFUQ01A7A2W productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 817 87.32 186/213 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [X.17.38.11] CAKDRLDSSGHYYHGVYYYGMDVW in-frame - ggatttagttttgaaaactatggcatgcattgggtccgccaggctccaggcaagggcctggaatgggtggcggtgatatcatatgacgcaagtaacaaatattatgcagacgccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatcttcaaataatcggcctgagagctgaggacacggctaaatactactgtgcgaaagatcgccttgacagcagtggtcattactaccacggggtctactactacggaatggacgtctggggcccagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6327 JY8QFUQ01A0LEW productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + tggatacaccttcaccagttactatatgcactgggtccgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6328 JY8QFUQ01BJDQ8 No results 6329 JY8QFUQ01B0Q68 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 895 88.44 199/225 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-22*01 F 2 8 10 14 8.10.14 [2.17.38.11] CTSRYYDPSGYWSDPW in-frame + tctctgggggtcaccttcagtgacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcagagttgatggtgggacagtggactacgctgcacccgtgaaaggcagattcaccatctcaagagatgactccaaaaacacactatatctacaaatgaacagcctgaaaatcgaggacacagccatgtatttctgcaccagtcgatactatgatcctagcggttactggtccgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 6330 JY8QFUQ01CP0DL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6331 JY8QFUQ01BDF9A No results 6332 JY8QFUQ01C0A0U productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6333 JY8QFUQ01AONND No results 6334 JY8QFUQ01AHIGQ No results 6335 JY8QFUQ01A3YON productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6336 JY8QFUQ01BSCQK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcaCcaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6337 JY8QFUQ01AIX9W unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame + stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggatggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 6338 JY8QFUQ01BH98U unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CARPTYSSGRD#AFDTW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggactgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6339 JY8QFUQ01A4PD9 No results 6340 JY8QFUQ01CSW02 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + tctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6341 JY8QFUQ01B5B1Z productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6342 JY8QFUQ01CRVEX No results 6343 JY8QFUQ01CZJC9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6344 JY8QFUQ01CJ7SM No results 6345 JY8QFUQ01C8OZP No results 6346 JY8QFUQ01ARWC9 unproductive Homsap IGHV3-7*03 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAREVSD#FEMW out-of-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgctttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6347 JY8QFUQ01CCPNN unproductive Homsap IGHV3-53*04 F 791 85.58 184/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CARQTAPLWEL#DLW out-of-frame + ctcgggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttacttctgtgcgagacagactgcccccctttgggaactttggacttatggggccagggaaccctggtcaccgtctcttcagcatccccggaccagcccccaaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttc 6348 JY8QFUQ01ATL2Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 6349 JY8QFUQ01C3GYW No results 6350 JY8QFUQ01BC7K6 No results 6351 JY8QFUQ01BGPBX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CTKDYPDGRLLNHVLPFLT#W out-of-frame - cctctggattcacgtttgacgactatgccatgagttgggtccgccaggctccagggaaggggccggagtgggtctcaggtattattcctaatagtcgtgacagacactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagagcacagtgtatctgcaaatgaacaacctcagaggcgaggacacggccgtatattactgtacgaaagactatccggacggccgcctgctaaatcacgtccttccctttttgacacttggggcgagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6352 JY8QFUQ01BY17I No results 6353 JY8QFUQ01BA2VC productive (see comment) Homsap IGHV4-39*02 F 951 92.27 203/220 nt 91.82 202/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.16.38.11] CARRYSWNYERFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggaggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6354 JY8QFUQ01ACT7P productive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CTRDDRSVRGVTSDYW in-frame + ctctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatttttgtacgagagatgatcgctcggttcggggagtcacctcagactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6355 JY8QFUQ01A6EZC productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 848 89.15 189/212 nt 88.21 187/212 nt Homsap IGHJ6*02 F (see comment) 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 8 8 18 8.8.18 [0.16.38.11] CARSDFGAYPTYYYYFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 2 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) tggaggcaccttcagtagttacgcaatcagctgggtgcgacaggAcccctgggcaagggcttgagtggatgggggatcatccctaagtttggaagaacaaactacgcacagagtttccagggcagagtcacgattaccgcggacaaatctacgaggacagtctacttggagttgagtagcctgcgatctgaagactcgggcgtgtatttctgtgcgaggagtgacttcggggcctaccctacatactactactactttatggacgtctggggccgtgggaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6356 JY8QFUQ01ALRP1 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CASGGYSGSGEYFLR## out-of-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctgggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6357 JY8QFUQ01A3Z6E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6358 JY8QFUQ01CJVSG unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 7 X 8.7.X [1.17.38.11] CGRGGKQWL#YFDYW out-of-frame + stop codons ctctggcttcacttttaggggctatgctatgagctggctccggcagcccccagggaagggactggagtggattgggtatatttattaccctaggagtaccaactacaacccctccatccagagtcgagtcaccatatcagtagacacgtccgagaaccagttctccctgaagctgtattctgtgaccgctgcggacacggccgtgtatcactgtgggagagggggcaagcagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6359 JY8QFUQ01A8HIE productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6360 JY8QFUQ01DNPNL No results 6361 JY8QFUQ01DEC3Y unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 827 87.44 188/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [0.17.38.11] CARDSHKPPTVT#YFDYW out-of-frame + ctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggccccagggaaggggccggagtgggtctcagttatcagtggttggggtaatactatatattatgcagactccgtgagaggccggttcaccatctccagagacaactccaagaacatgctgtatctgcaaatgaatagcctgagagccgaggacacggccgtttattactgtgcgagagactcccacaaaccaccgacggtgacttgtactttgactactggggccagggaacccgggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctctgcagcaccctacgccagatgggaacgtggtcatcgccctgcctggtccagggcttcttcccccca 6362 JY8QFUQ01CJU11 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6363 JY8QFUQ01BY9TQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6364 JY8QFUQ01BR2DF productive (see comment) Homsap IGHV4-61*02 F (see comment) 686 79.19 175/221 nt 78.28 173/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [2.17.37.11] CARDRRRSIAGARHFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift) gtctctggtggccccaccatcgatgatggtgatttgtggacctggatccggcagcccgccgggCaagggactggaatggatcggttatgtctatgatgggcggggcaccaactccaaccctccctccggagtcgcgttaccctgtcacaagacacctcaaacaatcagttcttcttgaggttgaagtctgtgaccgcctcagacacggccgtctattactgtgcgcgagaccgccgtaggtcgattgccggagcgagacactttgactcctggggccagggaatcctggtcaccgtcgccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6365 JY8QFUQ01AHB8A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgcttagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6366 JY8QFUQ01CMM13 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 873 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] RAKDASRYYYNSYCDNW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatggccgaatcacaaactacgcggactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttcgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6367 JY8QFUQ01CZ0MI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctttttccccca 6368 JY8QFUQ01BNM4N unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRGDRRDF## out-of-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcagttccattaccatgaactggatgcgacaggctccagggaaggggctggagtacgtctcatcaattaataatgagggtggacacacactttacgcagactcagcgaagggccggttcaccatctccagagacaacgccgagaattcactgtatctgcaaatgaacaacctaagagtcgacgacacggctatatattactgtgtgagaggtgacaggcgtgacttctgggggccagggaaccctcgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 6369 JY8QFUQ01CZQWE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtGgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 6370 JY8QFUQ01CFX1X No results 6371 JY8QFUQ01AYFQH productive Homsap IGHV3-48*01 F 1009 95.43 209/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [2.17.38.11] CRGDPTQRDYG in-frame - gcctctgggttcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggctttcattcattactagtagtggtagtaccgtatactacgcagactctgtgaagggccgattcaccatctctagagacaatgtcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgccgcggtgaccctactcaacgtgactacgggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6372 JY8QFUQ01BWZ8Y No results 6373 JY8QFUQ01BA63F productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 795 85.98 184/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWGADAFDIW in-frame - ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccaaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6374 JY8QFUQ01DEHWK unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F (see comment) 302 75.23 82/109 nt 8 10 X 8.10.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (75,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggtcgtcgcatgcctggtccagggcttcttccccca 6375 JY8QFUQ01AF0GW No results 6376 JY8QFUQ01AIEDE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 330 88.24 75/85 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame + caccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6377 JY8QFUQ01ALUOL No results 6378 JY8QFUQ01AIDPR No results 6379 JY8QFUQ01CTQIN productive Homsap IGHV3-7*01 F 1013 96.33 210/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 6380 JY8QFUQ01BRXFV productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGSSGFNDAYFDNW in-frame - ctccggattcacctttaacacttattggatgaactgggtccgccaggctccagggaagggactggagtgggtggccaacataaaccaagatgggagcaggagacactatgtggactctgtgatgggccgattcaccatctccagagacaacaccaaggactcactgtatctgcaaatggacagcgtgagagccgaagacacggctgtctattactgtgcgaggggatctagtggattcaacgacgcctattttgacaactggggccagggaaccctggccacagtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6381 JY8QFUQ01BSW67 productive Homsap IGHV3-66*02 F 926 92.56 199/215 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame - cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6382 JY8QFUQ01C1QOH productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6383 JY8QFUQ01A1X52 productive Homsap IGHV3-48*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVENYSDSGGSFDYW in-frame - cctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaattactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 6384 JY8QFUQ01DTH5D productive (see comment) Homsap IGHV4-61*02 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 10 6 14 10.6.14 [1.17.38.11] CARGSSGFNDAYFDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggctgtctattactgtgcgaggggatctagtggattcaacgacgcctattttgacaactggggccagggaaccctggccacagtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6385 JY8QFUQ01A73ZK productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGXYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtnattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtctcgcctgcctggtccagggcttcttcccccagg 6386 JY8QFUQ01BBXZ8 No results 6387 JY8QFUQ01DSWTJ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 9 7 15 9.7.15 [2.17.38.11] CTSREHAFSGQFTGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GTC' (3 nucleotides at position 27 to 29 in the user submitted sequence), (do not cause frameshift); atgtgtctggtgtctccgtcaccagcGTCagtcactggtggacctgggtccgccagcccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgcttttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6388 JY8QFUQ01A7H7S No results 6389 JY8QFUQ01DMG6J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 6390 JY8QFUQ01CY8KN unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 93.58 204/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 9 7 X 9.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6391 JY8QFUQ01A928N productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFHYW in-frame + tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttcactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6392 JY8QFUQ01C8K4D productive Homsap IGHV3-21*04 F, or Homsap IGHV3-48*04 F 823 87.04 188/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARVKYSSSWSSILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 6393 JY8QFUQ01BTH7J No results 6394 JY8QFUQ01AIAF1 productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGGTVTAGGPRIVFGYW in-frame + tggctacaccttcaccgactactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctgacggtggtagcacaaagtatgcacagaaatttcagggcagggtcgccgtgaccagggacacgtcaattagcacagcctacattgaggtgaccagactgacatctgacgacacggccgtgtattattgtgccagaggagggactgtgacagcaggtggtcctcgtattgtctttgggtactggggccagggaacgttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6395 JY8QFUQ01AFN53 productive (see comment) Homsap IGHV3-48*01 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAMRETSRSSLRHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttccaatgccatgaactgggtccgccaggctccagggaagggctggaatggatttcatacattacaggtagcagtggtatcataaactacgcagactctgtgaagggccgattcaccgtctccagagacaatgccaagaattctctgtatctgcaaatgaacagcctgagcgccgacgacacggctgtctattactgtgcgatgcgagagaccagcaggtcgagtcttcgccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6396 JY8QFUQ01B8XV5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDRLTISALDY## out-of-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggtagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6397 JY8QFUQ01BMWKM productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 877 89.81 194/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6398 JY8QFUQ01BO54Y productive (see comment) Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt 83.49 182/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.16.38.11] CARYRGSYYDYGGVDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) acctctggcttcagattccgtgactactacatgacgtggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggGggccgcttcaccatctccagggacaacaccagGgaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6399 JY8QFUQ01DQTGB productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6400 JY8QFUQ01AIE5T productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 9 8.7.9 [1.17.38.11] CARGGSYFWDW in-frame - tctctggtggctccaccaataataactactggacttggatccggcagcccccagggaagggaatggagtgggttgggtatgtcaattatgctgggaccaccaactacaacccctccctcaagagtcgagtcactatttcagtggactcgtccaagaaccagttctccctgagggtgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggcagctacttctgggactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6401 JY8QFUQ01CY8EN No results 6402 JY8QFUQ01C3NRO No results 6403 JY8QFUQ01BKJB5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctccggattcaccttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 6404 JY8QFUQ01BD7D1 No results 6405 JY8QFUQ01CI8VK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggagggggctgGgagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6406 JY8QFUQ01AXGGN productive Homsap IGHV4-61*06 ORF (see comment) 775 83.56 183/219 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [1.17.38.11] CARGMATIKSVRFDPW in-frame + Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaatcggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcagg 6407 JY8QFUQ01C8U6C productive Homsap IGHV3-7*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6408 JY8QFUQ01CUGM1 No results 6409 JY8QFUQ01BSWFL productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 6 10 9.6.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatgtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6410 JY8QFUQ01DETBY productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 9 8.7.9 [4.17.38.11] CARGGPHFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6411 JY8QFUQ01CQ336 No results 6412 JY8QFUQ01CO3PK unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 2 8 7 X 8.7.X [1.17.38.11] CASSVRGPAMAW##W out-of-frame + ctctggtggctccatcagtaattacttctggagctggatccggcagcccccagggaagggtctggagtggattgcgaatatctattacaatgggaacaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtctaagaaccagttctccctgaaggtgaggtctgtgaccgctgcggacacggccgtgtattattgtgcgagctcagttagggggccagctatggcctgggaactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6413 JY8QFUQ01AJL3W No results 6414 JY8QFUQ01DJA9J productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 90 to 95 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6415 JY8QFUQ01B7WHM No results 6416 JY8QFUQ01C44RE productive (see comment) Homsap IGHV3-69-1*02 P (see comment) 701 80.93 174/215 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARTPCSGGNCYLRGHDLW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01C44RE ; 7 AA in Homsap_IGHV3-69-1*02), and low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcgggtatttattattgtgcgcggacgccttgcagtggtggaaattgttaccttagaggccacgacctctggggccagggaacccaggtctccgtttccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga 6417 JY8QFUQ01C43M3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6418 JY8QFUQ01CBCEN No results 6419 JY8QFUQ01B1OCM No results 6420 JY8QFUQ01B8EVU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEEGATGVYYVDH# out-of-frame - agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6421 JY8QFUQ01CEIZC unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*04 F or Homsap IGHV4-34*06 F or Homsap IGHV4-34*07 F or Homsap IGHV4-34*09 F or Homsap IGHV4-34*10 F or Homsap IGHV4-34*12 F or Homsap IGHV4-34*13 F 97 58.44 45/77 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found tatggtgggtccttcagtacttactactggacatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 6422 JY8QFUQ01AKM97 No results 6423 JY8QFUQ01CKYVH No results 6424 JY8QFUQ01CHV6I No results 6425 JY8QFUQ01DEKWC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 121 66.13 41/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame + ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcctgctgagcctcgacagcaccccccgaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 6426 JY8QFUQ01DV24N productive (see comment) Homsap IGHV3-48*02 F 1026 97.24 211/217 nt 96.31 209/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD1-1*01 F 2 7 8 20 7.8.20 [1.17.38.11] CASGERKDYEVRRDYYHGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) cctctggactaccttcagcagctatagtatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatatattagtagtactagtagtaccataaAactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6427 JY8QFUQ01A6TLD unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null - No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6428 JY8QFUQ01AC1CW No results 6429 JY8QFUQ01BHGLW No results 6430 JY8QFUQ01AJCQE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6431 JY8QFUQ01DJ81N unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CTRELRVAAARDGVDIW# out-of-frame + cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggcccaaagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 6432 JY8QFUQ01AV8UD unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 96 95.24 20/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcatcttcagtga 6433 JY8QFUQ01A3KTS No results 6434 JY8QFUQ01DQ766 No results 6435 JY8QFUQ01BXIFP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6436 JY8QFUQ01C8WEH No results 6437 JY8QFUQ01CJEBO productive (see comment) Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F 356 88.04 81/92 nt 86.96 80/92 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 X X 14 X.X.14 [X.X.30.11] CARSCTDGVCRFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 79 of V-REGION: 4 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaagacaacgccaagaactcactgtatctgcaaatgaacaacctgagagccgaggactcggctgtgtattactgtgcgagatcctgtactgatggtgtgtgtcgtttctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6438 JY8QFUQ01BQ8SE No results 6439 JY8QFUQ01BEMAB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 868 89.35 193/216 nt 88.89 192/216 nt 8 8 X 8.8.X [1.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaggggcgtggagtggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6440 JY8QFUQ01BP2SY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 461 94.17 97/103 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacata 6441 JY8QFUQ01B09EX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6442 JY8QFUQ01BHUFG productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6443 JY8QFUQ01BIR27 unproductive Homsap IGHV4-61*01 F 947 92.31 204/221 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-6*01 F 3 10 7 X 10.7.X [1.17.38.11] CTRGGSTLMTAR## out-of-frame + tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgagggggggcagtacacttatgacagcccgtgggggacaggggacccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccccgag 6444 JY8QFUQ01BNOAH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6445 JY8QFUQ01A1FKO No results 6446 JY8QFUQ01CKCDG productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg 6447 JY8QFUQ01CHUX9 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6448 JY8QFUQ01ARTHF productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6449 JY8QFUQ01CE1ZB No results 6450 JY8QFUQ01CAGRS productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6451 JY8QFUQ01BCUEG No results 6452 JY8QFUQ01A2U68 No results 6453 JY8QFUQ01BZOVO productive (see comment) Homsap IGHV3-9*01 F 931 92.59 200/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctggattcaccGtttcatgattataccatgGcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtGggtaacatagactatgcggcctctgtgaaGgggccgattcaccgtctCccagagacaacgccaataactccCctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6454 JY8QFUQ01BYP9J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPLSV#W out-of-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 6455 JY8QFUQ01DMCLO No results 6456 JY8QFUQ01CRFYZ No results 6457 JY8QFUQ01CKJVN No results 6458 JY8QFUQ01CYHGF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6459 JY8QFUQ01A53H6 No results 6460 JY8QFUQ01CGXKQ unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYG#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6461 JY8QFUQ01DGCB3 unproductive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame + stop codons ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggatggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 6462 JY8QFUQ01B0B9Z No results 6463 JY8QFUQ01C6J6T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6464 JY8QFUQ01BVQFR productive Homsap IGHV1-18*01 F 911 92.45 196/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 3 7 8 15 7.8.15 [X.17.38.11] CARDAQQWLVLQAFDYW in-frame - ttacaccctttgccagctatggtatcagttgggtgcgacaggcccctggacaagggcttgagtggatgggatgggtcagcgcttacaatggtcacacaaaatatgcacagaagctccagggcagagtcaccatgaccacagacacatccacggatacagcctacatggagctggagagcctgagatctgacgacacggccgtttattactgtgcgagagatgcgcagcagtggctcgtattacaggcatttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6465 JY8QFUQ01ALI3N productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 6466 JY8QFUQ01BLYLG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6467 JY8QFUQ01AGCPF No results 6468 JY8QFUQ01BSHE2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6469 JY8QFUQ01B6V0U No results 6470 JY8QFUQ01AHFKE unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 6471 JY8QFUQ01AKC1Q No results 6472 JY8QFUQ01BL015 No results 6473 JY8QFUQ01BVA5Q productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 687 92.5 148/160 nt 91.88 147/160 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 X 7 13 X.7.13 [X.8.38.11] CARRGSYGSGSYYPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gaaggggctggagtggattgggagtatGcttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 6474 JY8QFUQ01CVTI4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaacttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6475 JY8QFUQ01BK81H productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgcgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 6476 JY8QFUQ01B5BQH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6477 JY8QFUQ01DA6SD No results 6478 JY8QFUQ01A0PJV No results 6479 JY8QFUQ01CK56M No results 6480 JY8QFUQ01DO80W productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 11 8.8.11 [1.17.37.11] CNLHPYGDSSDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) ctctggactcaccttcagtcgcctctggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatagatagtgatgggaataacataatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaaacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtaaccttcatccctacggtgactcctccgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 6481 JY8QFUQ01BAON0 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1009 95.89 210/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CVRGDYGGDPRTLLRP#YGLDVW out-of-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgacccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6482 JY8QFUQ01AEDZX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAKDQAVAGGFDYW in-frame - tctggatttacctttagctcctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtcgcaattattagtggtagtgatggtcgcacatactacgccgactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaataaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcaagcagtggctggaggatttgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6483 JY8QFUQ01APX8X unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI## out-of-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6484 JY8QFUQ01CZGJ2 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); tctggattcaccttcgataactatgGgcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6485 JY8QFUQ01CI9GM productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDWPSSGWSHFEAW in-frame + ctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6486 JY8QFUQ01CJTG8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 8 8.8.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6487 JY8QFUQ01DKV4A unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 6488 JY8QFUQ01DAV5Y No results 6489 JY8QFUQ01C0MUL productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*06 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 7 22 8.7.22 [1.16.38.11] CARDFLAPNRFGVFDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 89 in the user submitted sequence), (cause frameshift) gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcagggtctggaatggttggcaatgatatggtatgtggaaataaaaaatactacgcagactccgcgacgggccgattcaccatctccagagacaattctgagtacacgctgtctcttcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagggatttcttagccccgaatcgttttggagtgtttgactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6490 JY8QFUQ01DEFYH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 800 86.05 185/215 nt 85.12 183/215 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-17*01 F 3 7 8 X 7.8.X [1.16.38.11] CARDAGNTWPNYFDH#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctctggattcagcttttcaattatggcatgaactgggtccgccaggctccagggaggggctggagtgggtcgcatttattagcggtgctggtgaaaatacttactacgcagactccgtgaagggccgattcgccatctccagagacgattcgagggacacactgtatctccaaatgagcagcctgagagccgaggactcggccctctattattgtgcgcgagatgcgggcaacacctggcccaactactttgaccacgtggggccagggaaccctggtcaccgtctcctcgggtgagtcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 6491 JY8QFUQ01CDVK0 unproductive (see comment) Homsap IGHV4-61*02 F 925 90.99 202/222 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [2.17.38.11] CAREK**SV#NWFDPW out-of-frame + stop codons gtctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgctagagaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6492 JY8QFUQ01BQZBN No results 6493 JY8QFUQ01CNUJW No results 6494 JY8QFUQ01COJDW productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6495 JY8QFUQ01C4X4D productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 6496 JY8QFUQ01AKK7C productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6497 JY8QFUQ01CRETZ productive Homsap IGHV3-7*01 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 219 92.16 47/51 nt 8 8 8 8.8.8 [2.17.38.11] CARSYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ggctctgggttcttctttggtagttattggatgacctgggtccgccaggctccagggaagggactagagtggttggccaacctaaagcacgatggcagtggaatatcctatgcggactctgtgaagggccggttcaccatttccagagacaacgccaagaacacagtgtatctgcaaatgaatagcctgagagtcgaagacacggctgtctattattgtgcgagaagttacggtatggacgtctggggccacgggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6498 JY8QFUQ01DQXTY productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 996 95.0 209/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARPGVGASSFIDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); gggttctggatacagcttaccggcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaCccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6499 JY8QFUQ01AIISH productive Homsap IGHV3-11*01 F 110 61.04 47/77 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.25.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcactttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6500 JY8QFUQ01BI3YG No results 6501 JY8QFUQ01BTU7H productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6502 JY8QFUQ01CCMJ5 productive (see comment) Homsap IGHV4-61*02 F (see comment) 714 80.27 179/223 nt 79.37 177/223 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARERGTAVGGARELDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); gtgtctggtgggccccgtcagcagtgatggttactAcctggacctggatccgccagcccgccgggcagggactggagtgggtcggacgtgtttccagtcgtgggggAgaccgactacagttcctccctcaagagccgaatcaccatgtcaatagacacgtctaagaaccagttctccctgaggttgaactctgtgaccgccgcagacacggccctatactactgtgcgagagagcgcggtactgcggttggcggagcgagagaacttgactcctggggccagggatcccaggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6503 JY8QFUQ01DB5QJ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttccccca 6504 JY8QFUQ01A451K productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6505 JY8QFUQ01BLC8W unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 158 91.89 34/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttaacagccatgccatgagttgg 6506 JY8QFUQ01AKJR2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1013 96.33 210/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6507 JY8QFUQ01CRCUI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6508 JY8QFUQ01BGY05 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1037 96.83 214/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaggagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6509 JY8QFUQ01CFF3G unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6510 JY8QFUQ01ARJM3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 690 79.55 175/220 nt 79.09 174/220 nt Homsap IGHJ6*02 F (see comment) 148 70.97 44/62 nt Homsap IGHD5-24*01 ORF 3 8 8 15 8.8.15 [2.17.38.11] CASGGNAYITRRGLEVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); agcttccggcttcaccctcagtaaacactggatgcattgggtccgccagccttcagggaagggcctggagtttgtcgcgcgtctgagtaatgatggatataccacaagttatgcagactccgtgcagggccgcttcactatctccagagacgccgccgcgaacgcgctgAtttttgcagttgaccggtctgagagccgacgacacgggtgtctattactgtgcaagtgggggaaatgcctacatcacgcggcgtggtctggaggtctggggccgggggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6511 JY8QFUQ01DDZNR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 821 85.97 190/221 nt 84.62 187/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKGIVGASMQADWFHPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'AT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); ggcctcctggattcgtcATttgggcgactatgcgatgagGctgggtccggcaggctccagggaTgggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 6512 JY8QFUQ01A2EFK No results 6513 JY8QFUQ01DE7ZV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6514 JY8QFUQ01CYBAX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 7 10 8.7.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6515 JY8QFUQ01AFPO8 No results 6516 JY8QFUQ01CXD2W No results 6517 JY8QFUQ01AVYZP productive Homsap IGHV1-3*01 F 903 91.59 196/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGEPLGGDYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcacttcttatgctgtaaactgggtgcgccaggctcccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagtttcagggcagagtcaccattaccagggacacatccgcggacacagtcttcatggagctgagcagtctaagatctgaagacacggctgtgtattattgtgcgagagatggggagccactgggaggcgactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6518 JY8QFUQ01DF7OW No results 6519 JY8QFUQ01BZEHF No results 6520 JY8QFUQ01BCJD8 unknown (see comment) Homsap IGHV3-74*03 F 136 52.36 100/191 nt 8 8 X 8.8.X [1.17.29.X] null + No rearrangement found stop codons ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 6521 JY8QFUQ01AH7K3 No results 6522 JY8QFUQ01B48P7 productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6523 JY8QFUQ01B69I7 unknown (see comment) Homsap IGHV1-2*02 F 503 86.47 115/133 nt 85.71 114/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tggatacattttcaccggctactattTtacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc 6524 JY8QFUQ01ANOND productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6525 JY8QFUQ01AC0IK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaAaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6526 JY8QFUQ01AGAIC No results 6527 JY8QFUQ01CDEJX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6528 JY8QFUQ01BL6W5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6529 JY8QFUQ01BV1R6 unknown (see comment) Homsap IGHV3-49*01 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*05 F 88 51.91 68/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ttctggattcacctttggtgactatgctatgagctggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 6530 JY8QFUQ01DAHNB No results 6531 JY8QFUQ01DH31Z No results 6532 JY8QFUQ01AZL76 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6533 JY8QFUQ01AE2O7 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 118 50.72 106/209 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6534 JY8QFUQ01CGEWF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAREGGSGPGSSEDYFDYW in-frame + ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagagggggggtcggggccaggttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6535 JY8QFUQ01C0UL8 productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAAVGVGSAVSFQYW in-frame - ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttattacggtggaaccacatattacgctgactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6536 JY8QFUQ01DTB26 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6537 JY8QFUQ01CIZB1 No results 6538 JY8QFUQ01BWGSR unknown (see comment) Homsap IGHV3-7*01 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 6539 JY8QFUQ01A6T5J productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + tctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 6540 JY8QFUQ01CDHWB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6541 JY8QFUQ01B3X75 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6542 JY8QFUQ01C9Q5C productive Homsap IGHV4-31*06 F 1001 95.0 209/220 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 10 7 15 10.7.15 [1.17.38.11] CARVIIDDSGGNYFDYW in-frame + tctctggtgcctccatcagcagtggtatttactactggagctggatccgccagcacccaggggagggcctggagtggattgggtacatctctgacagtgggagcacctactacaacccgtccctcaagagtcggtttaccgtatcagtggacacgtctaagaaccagttctctttgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagtaataatagatgactccggtggtaactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6543 JY8QFUQ01CMLXH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6544 JY8QFUQ01CAWBX No results 6545 JY8QFUQ01DBL7Y productive (see comment) Homsap IGHV2-5*02 F 1044 92.21 225/244 nt 91.8 224/244 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CAHISASISTSCHDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcagcttctctgggttctcactcagcactgttggagtgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcactcatttattgggatgacgataagcgttacagttcatctctaaaaagGtcgcctcaccatcaccggggacactcccaaaaaccaggtggtcctgacaatgaccaacatggaccctgtggacacagccacatattattgtgcacacatctcagcgagtattagcaccagctgccatgacctctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 6546 JY8QFUQ01BK7D8 No results 6547 JY8QFUQ01BWUPM No results 6548 JY8QFUQ01BAIEJ No results 6549 JY8QFUQ01CZH0L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.16.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggagggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6550 JY8QFUQ01DAFG7 No results 6551 JY8QFUQ01BO9QZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6552 JY8QFUQ01BR2I0 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6553 JY8QFUQ01C42VY productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6554 JY8QFUQ01BB1TT No results 6555 JY8QFUQ01AG2W0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6556 JY8QFUQ01AC4B0 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 470 68.87 146/212 nt 68.4 145/212 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [0.17.38.X] null - Rearranged sequence but no junction found however the closest V is a pseudogene Low V-REGION identity (68,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 64 of V-REGION: 'CAA' (3 nucleotides at position 93 to 95 in the user submitted sequence), (do not cause frameshift); ctggattaaccctcagtgaccactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtCAAaacatatactacagagactcagtgcggggccgattcaccatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6557 JY8QFUQ01BKRAL unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + stop codons tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgtaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6558 JY8QFUQ01BX7QA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6559 JY8QFUQ01DE0Z1 No results 6560 JY8QFUQ01C6CJJ No results 6561 JY8QFUQ01AQQPC productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 900 85.66 209/244 nt 85.25 208/244 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 93 of V-REGION: 'CG' (2 nucleotides at position 209 to 210 in the user submitted sequence), (cause frameshift); gaccctcaccctgacctgcgacttctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccCGacatggggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6562 JY8QFUQ01BCMDL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 405 77.78 105/135 nt 76.3 103/135 nt 7 6 X 7.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6563 JY8QFUQ01C97NB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactcag 6564 JY8QFUQ01DEMSU unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 921 92.52 198/214 nt 90.65 194/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 2 8 7 X 8.7.X [1.17.37.11] CARFGPTYST#DYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'T' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) tctggattcacctttaccGaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtgtagtggtgaaactacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaaTcagtctgagagccgaggacacggccattattactgtgcgagattcggacctacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6565 JY8QFUQ01DIJF9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ6*02 F (see comment) 139 69.35 43/62 nt Homsap IGHD3-3*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAKSPIFGVEKDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcagctttagtagctatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctccgctattgatactggcggtgatcttacgttccacgttgactccgtgaagggccgcttcaccatctccagggacaattccaagaatacgctgtatctgcaaatgagcggcctgagagtcgaagacacggccgtatattactgtgcgaaatctccgatttttggagtggagaaggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6566 JY8QFUQ01AH82H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6567 JY8QFUQ01BA91L No results 6568 JY8QFUQ01DF5O3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 665 83.51 157/188 nt 82.98 156/188 nt Homsap IGHJ1*01 F 116 69.23 36/52 nt Homsap IGHD4-11*01 ORF 2 X 8 6 X.8.6 [X.16.38.11] DSRNPRVG in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,51% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tgagtggggtccgccaggctccagggaaggggctggagtgggtctcagGgcttttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtagggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag 6569 JY8QFUQ01DXA7M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6570 JY8QFUQ01BG3CJ No results 6571 JY8QFUQ01A5CAD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 555 78.14 143/183 nt 8 8 X 8.8.X [1.17.26.X] null - No rearrangement found Low V-REGION identity (78,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaacgccgaaccggtgacggtgtcgtggaactcag 6572 JY8QFUQ01AZ70S unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGSGRDPYGINV## out-of-frame - cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6573 JY8QFUQ01BALFI productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1027 96.8 212/219 nt 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARPGVGASSFIDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); ggttctggatacagctttaccggcCtactggatcggctgggtgcgccagatgcccgggaaaggcctggagCtgggtggcgatcatctatcctggtgactctgaaaCccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6574 JY8QFUQ01B5K4J unknown (see comment) Homsap IGHV5-51*05 F 167 53.37 111/208 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6575 JY8QFUQ01AYW1V productive (see comment) Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6576 JY8QFUQ01CM8PU No results 6577 JY8QFUQ01B8N16 unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 918 91.71 199/217 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6578 JY8QFUQ01DMNTN unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F or Homsap IGHV4-61*02 F 148 62.92 56/89 nt 10 1 X 10.1.X [1.17.X.X] null - No rearrangement found stop codons tctctggtggctccatcagcagcagtagttactactcgacctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6579 JY8QFUQ01A701H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 802 85.39 187/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARLAMLRGVPTWFDPW in-frame - gcctctggattcgacctcactacctattccatgagctgggtccgccagactccagggatggggctggagtgggtctcttcaataagtagcaagagtaataccgtctcctacgcagactcagtgaagggccgattcaccatctccaaagacaacgccaaaaacttattgtttttgcaaatggacagcctgagagacgaggacacggctatttattactgtgcgagacttgcaatgcttcggggagtccccacctggttcgacccctggggccagggagccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6580 JY8QFUQ01CO7PU No results 6581 JY8QFUQ01CJJI3 No results 6582 JY8QFUQ01DEE6N No results 6583 JY8QFUQ01B6475 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcccctttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6584 JY8QFUQ01C9UQH productive Homsap IGHV3-7*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 6585 JY8QFUQ01CMGM0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 2 8 8 17 8.8.17 [1.17.37.11] CAKDWSIGARFPQGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 76 of V-REGION: 2 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctctttcattagtggtaatggtggtagcatagactacgcagactccgtgaagggccggcaccatctccagagacaattccaagaatacgctgtatctgcaaatgaatagtctgagagccgaggacacggccgtctattactgtgcgaaagattggagtataggagcacgtttcccccaaggagcttttgatatctggggccaaggggaattggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtctagggcttcttccccca 6586 JY8QFUQ01DFGPB unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFGGSYNLVAY## out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6587 JY8QFUQ01CO7VN productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6588 JY8QFUQ01CR24N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6589 JY8QFUQ01A3HEN unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 1 8 8 16 8.8.16 [0.17.38.11] CAKITPL*QEWSIIPTTG in-frame - stop codons in FR2-IMGT at codon 52 of V-REGION: 'T' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); ctctggtcatttttggccactataccatgagctgggtccgccaggctccagggaaggggctggagtTgggtctcagctattggtaatagtggtgatattacatactacgcagactccgcgaggggccggttcaccatctccagagacaattcccagaacacactgtatctgcaagtgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaataacccccctatgacaggagtggtccattataccgactactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6590 JY8QFUQ01DNSYR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'C' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactgatagcggacgcagcacatGactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaagCaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6591 JY8QFUQ01BJD1H No results 6592 JY8QFUQ01BCUAN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 660 90.57 144/159 nt 89.94 143/159 nt 8 8 X 8.8.X [1.17.19.X] null + No rearrangement found in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); tcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaac 6593 JY8QFUQ01C7ZZV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CAKEEVPNDYW in-frame + ctctggattcacctttagcaatgctgccatgacgtgggtccgccaggctccagggaaggggctagagtgggtctcaggtattagtattagtggtgatagaacatattacgcagactccgtgaagggccggttcaccatctctagagacaattccaagaataccgtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccag 6594 JY8QFUQ01A78VU unknown (see comment) Homsap IGHV3-30*05 F, or Homsap IGHV3-30*13 F or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F 129 55.3 73/132 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcaacgtcagtggatactggatgcactgggtccgccaagtgccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 6595 JY8QFUQ01A3VO9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6596 JY8QFUQ01DUA6P No results 6597 JY8QFUQ01BDEJ4 productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6598 JY8QFUQ01BADHK productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactca 6599 JY8QFUQ01B3JLF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatCggggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6600 JY8QFUQ01BE8EN No results 6601 JY8QFUQ01BSDXC productive Homsap IGHV1-69*04 F, or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAIPFSSSSAWFDPW in-frame + tggaggcaccttcagcagctatgtcatcagctggctgcgacaggcccctggacaagggcttgagtggatgggacatgtcattcctatgtttggtgtatctaacctcgcgcagaggttccagggcagagtcacaataaccgcggacacatccacgaccacagcctacatggaggtgaccaggctgagatctgaagacacggccgtctattattgtgccataccattcagcagctcgtcggcctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6602 JY8QFUQ01ANECA productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 641 89.87 142/158 nt 89.24 141/158 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 X 7 13 X.7.13 [X.7.38.11] CVREVTGVWDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); aggggctggagtggattggAcaaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6603 JY8QFUQ01B33A5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggcatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6604 JY8QFUQ01ATQ7U No results 6605 JY8QFUQ01BJ8VI productive (see comment) Homsap IGHV3-11*01 F (see comment) 681 79.09 174/220 nt 78.18 172/220 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [2.17.38.11] CVRDRSRGIADPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); gacgtctggattcaccttcactgactattgGgatgagttgggtgcgcctgAgccccagggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaaatttagtcattttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6606 JY8QFUQ01DPKOD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 495 69.59 151/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] VHT#AFW out-of-frame + Low V-REGION identity (69,59% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgaggacaactttggtgaacacgccatgggatggatccgccagtctccgggggggattcttcagtgggtcgctgcgatcagtggtgacggactgacggcgtttcacgcagacttcgtggagggtcgattcagcatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctattttgtgcacacactgccttctggggccggggatcccgggtcaccgtctcctccgcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6607 JY8QFUQ01BVMAB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 6608 JY8QFUQ01AFIEW productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6609 JY8QFUQ01CQJP3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6610 JY8QFUQ01BDYFI productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6611 JY8QFUQ01ADM49 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6612 JY8QFUQ01AQAV9 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 696 78.92 176/223 nt 78.48 175/223 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (78,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaaaGcacgttgtatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6613 JY8QFUQ01B0M8W productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 951 92.73 204/220 nt 91.82 202/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 10 7 12 10.7.12 [1.16.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctggCtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaaggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6614 JY8QFUQ01CXPI0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6615 JY8QFUQ01B6QWG productive (see comment) Homsap IGHV4-39*03 F 893 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift); tctccggtggctccatcaacagtagaaAattattattggggctggatccgccagccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6616 JY8QFUQ01CZRM7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 18 8.8.18 [1.17.38.11] CVRESGDYGGKYSKSYFDYW in-frame + ctctggattcactttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatcaattactagaagttctagttatatgtcctacgcagactcagtgaagggccgattcaccatctccagagacaatgccgagaattcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgagagaatcgggtgactacggtggtaaatatagcaagtcatactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6617 JY8QFUQ01BVSZ2 No results 6618 JY8QFUQ01C1NJL productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame - cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6619 JY8QFUQ01C4MHW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggAactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6620 JY8QFUQ01DJCMJ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6621 JY8QFUQ01BMLW8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6622 JY8QFUQ01A5LN2 productive Homsap IGHV3-33*02 F, or Homsap IGHV3-33*03 F 148 65.43 53/81 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 X X 14 X.X.14 [X.X.27.11] CATDDSNGWDEVADYW in-frame - gcctctggattcaccttcagctcccattggatgagctggatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagacagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6623 JY8QFUQ01A11FZ No results 6624 JY8QFUQ01DN99N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ3*01 F (see comment) 164 80.0 40/50 nt Homsap IGHD3-10*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLFGESSHTTFDDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctgttcggggagtcatctcatacnacttttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6625 JY8QFUQ01C7VAT unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 6626 JY8QFUQ01CV39H unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 867 87.44 195/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [2.17.38.11] CTNDHSMAVSAKHAFDV## out-of-frame - gtcctctggtgcctccatgagcagtagtgcatactactggggctgggtccgccagacccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttgggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 6627 JY8QFUQ01AE04Y unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 405 89.9 89/99 nt 8 6 X 8.6.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgac 6628 JY8QFUQ01BQI8F productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ1*01 F 215 90.38 47/52 nt Homsap IGHD5-12*01 F 3 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); cctctgacttaaTcggtcagtgacaattaGcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacggttcccagaacacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtatttttgtgcgagtggtggttattcgggctcgggtgaatatttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6629 JY8QFUQ01A0EFI No results 6630 JY8QFUQ01CZVE5 No results 6631 JY8QFUQ01AGDXX No results 6632 JY8QFUQ01CBZ9Q No results 6633 JY8QFUQ01DCG8G productive (see comment) Homsap IGHV3-48*04 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.16.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) acctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaatgagtggcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6634 JY8QFUQ01AWIFY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6635 JY8QFUQ01B2ARX productive Homsap IGHV3-33*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame + gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6636 JY8QFUQ01BVN7Z unknown (see comment) Homsap IGHV4-61*01 F 978 94.09 207/220 nt 93.64 206/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 110 to 121 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 6637 JY8QFUQ01DEBDW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaagggactacttccccgaaccggtgacggtgtcgtggaactc 6638 JY8QFUQ01DQT4B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gtctctggattcaccttcatcagttatggcatgagttgggtccgccaggTttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 6639 JY8QFUQ01CF2CB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6640 JY8QFUQ01B3AB2 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtgcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6641 JY8QFUQ01DM1N1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggGcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccaCggcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctcgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 6642 JY8QFUQ01AYRUD productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6643 JY8QFUQ01A1QLN productive (see comment) Homsap IGHV3-13*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.37.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccgggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6644 JY8QFUQ01A1K37 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6645 JY8QFUQ01C9F82 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + stop codons Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctccggattcagtttcagtacttataacatgaattgggtccgctaggctccagggaaggggctggagtgggtctcatccatggGgtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6646 JY8QFUQ01AM701 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 6647 JY8QFUQ01A55QU productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6648 JY8QFUQ01AQRKK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 400 77.61 104/134 nt 76.12 102/134 nt 7 6 X 7.6.X [1.17.12.X] null + No rearrangement found Low V-REGION identity (77,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6649 JY8QFUQ01BPRTG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-NL1*01 F 91 54.46 55/101 nt 8 8 X 8.8.X [0.17.X.X] null + No rearrangement found stop codons tggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6650 JY8QFUQ01DGQLY No results 6651 JY8QFUQ01BL3MM unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRSEYSSSNWFDP# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgaccctgggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6652 JY8QFUQ01APL75 productive Homsap IGHV3-7*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6653 JY8QFUQ01DTC10 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.16.38.11] CVRDLNWSFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) gcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggattcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6654 JY8QFUQ01ABFKK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGFW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6655 JY8QFUQ01B1BZ9 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 121 54.48 73/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons gtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6656 JY8QFUQ01AH2WA productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6657 JY8QFUQ01C7UO5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6658 JY8QFUQ01CUO45 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6659 JY8QFUQ01C7IPL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 270 68.25 86/126 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found Low V-REGION identity (68,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6660 JY8QFUQ01B2PNO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame + gtctggattcacgtttagaaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccc 6661 JY8QFUQ01CZEWL unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 506 70.75 150/212 nt 7 8 X 7.8.X [X.17.38.X] null - No rearrangement found Low V-REGION identity (70,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6662 JY8QFUQ01A15SR productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 643 77.78 168/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [X.17.38.11] CVRHVRRFWFDPW in-frame - Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggtttcacggttcagtggctctgctatgcactgggtccgccaggcttccgggaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6663 JY8QFUQ01A71E4 No results 6664 JY8QFUQ01ACLKX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - cctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6665 JY8QFUQ01CK26O productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt 82.03 178/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6666 JY8QFUQ01AXQ3V No results 6667 JY8QFUQ01BMRZ4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctggagttcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggggctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 6668 JY8QFUQ01BP7WV productive (see comment) Homsap IGHV4-61*05 F, or Homsap IGHV4-61*08 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [1.16.38.11] CARAKDHDDYLVDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcagcagtagtggtcactactggagttggatccggcagcccccagggaagggactggaattcattggaaaatctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatatcactagacacgtccaaaaaccatttctccctgcagctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 6669 JY8QFUQ01DGM3A productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact 6670 JY8QFUQ01C1VZ8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttct 6671 JY8QFUQ01CH9AF productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6672 JY8QFUQ01AFTGA productive (see comment) Homsap IGHV3-11*01 F (see comment) 724 81.94 177/216 nt 81.48 176/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.16.38.11] CARGYSQKGVFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcagtttcaaggaccactacatgagctggttccgccaggctccagggaaggactggagtgggttgcatacatcgatgccggtgggggtactgactactacgcagactctgtggagggccgattcgtcgtcgccagggaaaatgacaagaatttattgcttctgcaaatgcacagcctgacagtcgaagacacggccgtatattactgtgcgagagggtacagtcaaaaaggggtttttgaccactggggccagggaatcctggtcaccgtttccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggacttcttccccca 6673 JY8QFUQ01AMHM5 No results 6674 JY8QFUQ01DOKXO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6675 JY8QFUQ01AOVMQ productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgcgtggaact 6676 JY8QFUQ01AS19K No results 6677 JY8QFUQ01A36CM productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6678 JY8QFUQ01DO6LM productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 6679 JY8QFUQ01CO3VB No results 6680 JY8QFUQ01DR4J9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-49*01 F or Homsap IGHV3-49*03 F or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcgtctttggcgactatgcgatgagctgg 6681 JY8QFUQ01B9M12 No results 6682 JY8QFUQ01AUU0J productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGHW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6683 JY8QFUQ01DSC89 productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*04 F (see comment) 307 75.68 84/111 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 X X 13 X.X.13 [X.X.37.11] CARGGGGKSIPLDNW in-frame - Low V-REGION identity (75,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgtctggcttcacgttcagtagttatggcatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6684 JY8QFUQ01C6ILB unknown (see comment) Homsap IGHV4-30-2*04 F, or Homsap IGHV4-34*01 F or Homsap IGHV4-34*02 F or Homsap IGHV4-34*08 F or Homsap IGHV4-34*12 F or Homsap IGHV4-34*13 F or Homsap IGHV4-38-2*01 F or Homsap IGHV4-38-2*02 F or Homsap IGHV4-39*01 F or Homsap IGHV4-39*05 F or Homsap IGHV4-59*04 F or Homsap IGHV4-59*05 F or Homsap IGHV4-59*08 F 414 91.0 91/100 nt X X X X.X.X [X.X.33.X] null + No rearrangement found stop codons tctatggagtcgagtcaccatatgagtagacacctccaagaaccagttctccctgaaggtgagctctgtgatcgccgcagacacggctgtgtattactgtgcgagacgtaagggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6685 JY8QFUQ01CY3QB No results 6686 JY8QFUQ01C49AP No results 6687 JY8QFUQ01COADP No results 6688 JY8QFUQ01BINUU unproductive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 181 87.23 41/47 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.17.38.11] CSRLP*G#W out-of-frame + stop codons tctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactcccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 6689 JY8QFUQ01C0O0F No results 6690 JY8QFUQ01BJS1R productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 962 92.41 207/224 nt 91.96 206/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 7 7 8 7.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) ccgtctgcagcctctggattcattgtcaatagcactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6691 JY8QFUQ01A3I5W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6692 JY8QFUQ01CT3DH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6693 JY8QFUQ01C1AGN productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggGcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6694 JY8QFUQ01CUKBL productive Homsap IGHV4-61*02 F 830 86.43 191/221 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*01 F 2 10 7 19 10.7.19 [1.17.38.11] CAREAPKTAGDSYGSLAMDVW in-frame - tctctggtggctccgtcagtagtggttcttactactggagctggacccggcagcccgccgggaagggactggagtggattgggcgtgtccacagcggtggcagttccgactacaacccgtccctcacgggtcgagccaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgagtatttctgtgcgagagaggcgcccaagacagcaggtgattcctacggctctctcgctatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6695 JY8QFUQ01BKB7Y productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6696 JY8QFUQ01CACJX unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 416 75.68 112/148 nt 8 7 X 8.7.X [1.17.16.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CACJX ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (75,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgtatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactca 6697 JY8QFUQ01DC3ZI productive (see comment) Homsap IGHV3-7*01 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [2.17.38.11] CSRLLEEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gcctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggaAgtgggtggccaatatCaaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6698 JY8QFUQ01BROZ6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6699 JY8QFUQ01CXBH4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6700 JY8QFUQ01AXX5G unproductive (see comment) Homsap IGHV4-61*01 F 942 92.27 203/220 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CTRGAVHL*QPV# out-of-frame + stop codons ctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacacttatgacagcccgtggggacaggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6701 JY8QFUQ01B6IMA unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 700 91.02 152/167 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B6IMA ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 6702 JY8QFUQ01DLDLD productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame + tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatcccctgaccagcccctaaggtcttcccgctgacgcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6703 JY8QFUQ01C052J No results 6704 JY8QFUQ01CFH6C productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 6705 JY8QFUQ01CMR70 No results 6706 JY8QFUQ01CTNJK unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 97 52.14 73/140 nt 10 9 X 10.9.X [1.17.9.X] null - No rearrangement found stop codons tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6707 JY8QFUQ01AQGGA No results 6708 JY8QFUQ01AQY9A productive Homsap IGHV3-9*01 F 968 93.58 204/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDAMGGAGDWAAFGIW in-frame - cctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6709 JY8QFUQ01B9JFJ No results 6710 JY8QFUQ01A5GYE No results 6711 JY8QFUQ01CVDG8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKSITMVRGLI#YHFDYW out-of-frame - ctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 6712 JY8QFUQ01B3WC4 No results 6713 JY8QFUQ01AF0ED No results 6714 JY8QFUQ01DIFDC No results 6715 JY8QFUQ01B9NVT No results 6716 JY8QFUQ01CCU8Z productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); cagcctctggattctccgtcagtaattactggatgcactgggtccgccaggctccagggaaggggctggtgtgggtctcacgtgttaatggtgatAgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6717 JY8QFUQ01BM5JT No results 6718 JY8QFUQ01C021D productive Homsap IGHV3-7*01 F 1041 97.27 214/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - ggcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6719 JY8QFUQ01A1KW0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 412 88.46 92/104 nt 87.5 91/104 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 6720 JY8QFUQ01C6766 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6721 JY8QFUQ01CV2GG productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6722 JY8QFUQ01DGX17 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6723 JY8QFUQ01CK5JU No results 6724 JY8QFUQ01BM9IX unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 87.56 190/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CAKEASPSGG*##HFDHW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtcgcacttattagcgatagggctgataaaacagcgtacgcagggtccgtgaagggccgattcaccatctctagagacaattccaagaatatattatatcttcaaatgaacagcctgagagccgacgacacggccgtatattattgcgcgaaagaagcctccccctcgggggggtgacgaccactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6725 JY8QFUQ01A6WE1 unknown (see comment) Homsap IGHV3-7*01 F 1026 96.77 210/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6726 JY8QFUQ01AE1O5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6727 JY8QFUQ01DQQ34 No results 6728 JY8QFUQ01A0NXG No results 6729 JY8QFUQ01BE1FW unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 6730 JY8QFUQ01CFT4U No results 6731 JY8QFUQ01CMP8A No results 6732 JY8QFUQ01AE0CK unproductive Homsap IGHV4-4*07 F (see comment) 688 80.09 173/216 nt 79.63 172/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-9*01 F 1 8 7 X 8.7.X [2.17.38.11] CARESTNSIGDPRHLD#L out-of-frame - Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'CAANACGAC' (9 nucleotides at position 19 to 27 in the user submitted sequence), (do not cause frameshift); gtctctggtggccccatcCAANACGACatggacttctattggacgtggatccggcagtccgccgggaggggactggagtggctcggacgtgtctatatgaatggcattagtgaccacaatccagtcttcactagtcgtctcaccatgtccattgacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggactcggccctatattactgtgcgagagaaagtactaattcgattggcgacccgagacaccttgactcttgggccagggaaggttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6733 JY8QFUQ01CC1QB unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6734 JY8QFUQ01DHA3U productive Homsap IGHV3-48*03 F 802 85.39 187/219 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [2.17.38.11] CVRQTGDYYFFGLDVW in-frame - gcctctggattcgccttcaaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6735 JY8QFUQ01C85QL productive Homsap IGHV3-7*01 F (see comment) 733 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6736 JY8QFUQ01A3VFN No results 6737 JY8QFUQ01CAXY5 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEFGEGPDWELLP#YFHYW out-of-frame + cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaatttggggagggccctgactgggaactactaccagtactttcactattggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtccgtngcatgcctggtccagggcttcttccccca 6738 JY8QFUQ01A0X3X productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F (see comment) 804 84.75 189/223 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-10*01 F 3 8 10 16 8.10.16 [1.17.38.11] CARIWEPSITFLHTFDVW in-frame + Low V-REGION identity (84,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcggggttcacctttggtgactatgctatcagttggttccgccaggctcctgggaaggggctggagtggattgctctccttaggagcaaaccttataattcaccaacacaattcgccacgtctgtgaaaggccgattcactgtctcaagagatgactcggaaagtgtcgcctatctgcacatgaacagcctgcaaaccggggacacagccgtgtattattgtgccagaatatgggaaccaagtattactttccttcatacatttgatgtctggggccgagggacacgggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6739 JY8QFUQ01CTKV2 unknown (see comment) Homsap IGHV3-7*02 F 100 57.83 48/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found ctctggattcgcctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6740 JY8QFUQ01CXIGS productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPHHNSGYSFDHW in-frame + cgtctgatttcaacgtcggtgactttgacatgcactgggtccgccagactccagacaaggggctggagtgggtggcacttttttggtatgacggaaagaggaaatattatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatggacagcctgagagccgacgacacggctacctacttttgtgcgaggcctcatcataatagtggttattcctttgaccactggggccagggaacccaggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6741 JY8QFUQ01CRE9K No results 6742 JY8QFUQ01AJBT6 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6743 JY8QFUQ01CFIT0 productive (see comment) Homsap IGHV3-11*01 F (see comment) 693 80.18 174/217 nt 79.26 172/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [1.17.37.11] CVRDRSRGIADPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cgtctggattcaccttcactgactattggatgagttgggtgcgcctgaccccaGgggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaaatttagtcttttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttcccc 6744 JY8QFUQ01C1HPT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6745 JY8QFUQ01AQFXP No results 6746 JY8QFUQ01A1WEO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSRLGRDTGWPP#ENW out-of-frame - cctctggattcaccgtgaatagttgtgccatgagctgggtccgccaggttccagggaaggggccggaatgggtctcaactcttggtatcagggacgatagtgcatactacacagactccgtgaagggccggttcaccatctccagggacaaatccaagaacactctgtctctgcaaatgaacagcctgagagtcgaggacacggccctatattactgtgcgaaatcccgtttggggcgtgacactggctggccccccttgaaaactggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6747 JY8QFUQ01AMLYW No results 6748 JY8QFUQ01DE0U1 No results 6749 JY8QFUQ01CT2N6 No results 6750 JY8QFUQ01DNY7K productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.17.38.11] CVKRLEAVADDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttagcagctatgccatAgggctgggtccgccaggctccagggaAaggggctggagtgggtctcaactattagtggcagtggtcggagcgcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaatacgatgtctgtacaaatgagcggcctgagagccgacgacacggccatatattactgcgtgaaaaggttggaagcagtggctgatgatgcctttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6751 JY8QFUQ01CT6MZ productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 6752 JY8QFUQ01BW86R No results 6753 JY8QFUQ01ACO2Q No results 6754 JY8QFUQ01AR84C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 6755 JY8QFUQ01BX7TJ unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 7 X 8.7.X [4.17.38.11] CARGDPIFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccattttcatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6756 JY8QFUQ01BYRXT productive Homsap IGHV3-21*04 F (see comment) 662 78.44 171/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame - Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6757 JY8QFUQ01B0M96 No results 6758 JY8QFUQ01AI6PH No results 6759 JY8QFUQ01BO7P5 productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARERSASIGGAGEIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tctctggcggccccatcagtggtggtggttactggagttggatccggcagcccgccgggaagggactggagtggatcggacatatttataatagtgggaacatcaactacagtccctccctcaagagtcgggttttcatgtcagtagacacctctaagaagcagttttccctgaggttgaactctgtgaccgccgcggacacggccgtgtattattgtgcgagagaacgtagtgcttcgattggcggagcgggagagattgactcctggggccagggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6760 JY8QFUQ01DBCBZ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 768 82.96 185/223 nt 82.51 184/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTSGPNGYHSTYPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaaGtacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaagcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgactagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 6761 JY8QFUQ01BW5FT productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcttccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6762 JY8QFUQ01C9K16 No results 6763 JY8QFUQ01BLLS0 unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-30*05 F 147 53.23 99/186 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6764 JY8QFUQ01CAGEH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6765 JY8QFUQ01BBXN0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccc 6766 JY8QFUQ01C3WX5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6767 JY8QFUQ01AHBEO productive (see comment) Homsap IGHV3-72*01 F 971 92.86 208/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccaAgggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6768 JY8QFUQ01DV4HU productive (see comment) Homsap IGHV3-7*01 F 882 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 92 of V-REGION: 'N' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgNaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggccagtcggtcttccccctgcgccctnctccaggagcacctccgagagcacagcggccctggctgccctggtcaaggatacttccccgaaccggtgacggtgtcgtggaactca 6769 JY8QFUQ01BAU1U productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgGggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccCgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgctggtccaggggcttcttccccca 6770 JY8QFUQ01CVWWZ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6771 JY8QFUQ01A0BVQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt 94.01 204/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 7 8 X 7.8.X [1.17.38.11] CAKKNIIIRGLI#YNFDYW out-of-frame - Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcaactttgcatgacctgggtccgccaggctccagggagggggActggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaacattataattcggggacttatttatacaactttgactactggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 6772 JY8QFUQ01BIOHN No results 6773 JY8QFUQ01B9RXS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 654 77.27 170/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (77,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6774 JY8QFUQ01CKP7P productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 6775 JY8QFUQ01BZ4W8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctngggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6776 JY8QFUQ01DIVTR productive Homsap IGHV1-3*01 F (see comment) 351 73.53 100/136 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 X 7 14 X.7.14 [X.X.38.11] CARGRYDSSGRGHEYW in-frame - Low V-REGION identity (73,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccagtttcagtatccattggaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6777 JY8QFUQ01CTMOR No results 6778 JY8QFUQ01BNH4P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6779 JY8QFUQ01CKBIE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6780 JY8QFUQ01DNQI8 unproductive Homsap IGHV4-61*02 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-3*01 F 3 10 7 X 10.7.X [1.17.38.11] CARDDLEWSKQKYSFYGVDV# out-of-frame - in CDR1-IMGT at codon 34 of V-REGION: 'T' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctctggtggctccatcaccTagtggtacttacttctggacctggatccggcagcccaccgggaagggactcgaatggattgggcgtatccacgccaatgggaacaacgtggtcaacccctccctcaggagtcgggtcaccgtgtcagtagacacgtccaggaaccaattctccctgaggctgagttctgtgaccgccgcggacacggccgtctattactgtgcgagagatgatttggagtggtccaaacaaaaatactccttttacggtgtggacgtctgggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctaagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6781 JY8QFUQ01CD8PO productive (see comment) Homsap IGHV2-5*02 F 1165 97.94 238/243 nt 97.53 237/243 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.16.38.11] CAHRRIRFGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6782 JY8QFUQ01CADHA No results 6783 JY8QFUQ01CODZI No results 6784 JY8QFUQ01AFF4Y unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSEFLLDG#YW out-of-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgagtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6785 JY8QFUQ01DA7FV No results 6786 JY8QFUQ01CLF5G No results 6787 JY8QFUQ01AXW2R unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 95 82.14 23/28 nt 7 X X 7.X.X [2.X.X.X] null + No rearrangement found tctccgggggacagtgtctctagcaaca 6788 JY8QFUQ01B5YQQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - tctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6789 JY8QFUQ01BSFQQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 751 83.33 180/216 nt 82.41 178/216 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD1-26*01 F 2 8 8 17 8.8.17 [1.17.38.11] CVRVPTQWFPPFHTHFDIW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tctggattcaccttTtagctcttttaccatgagctGgggtccgccagactccggggaagggcctggaatgggtctctgctatcagtggcagcgatgatcgcacatcttatgttgactccgtgaagggccgcttcaccatctccagagacacttccaggaatacactgtttctgcagatgaacagcctgagcgccgaagatacggccacatacttttgtgtgagagtccccactcagtggtttccacccttccacactcactttgacatctggggccagggaaccgtggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6790 JY8QFUQ01CE58M productive Homsap IGHV1-2*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARDGISMTLVRGVRPFDYW in-frame - tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6791 JY8QFUQ01C2NMH unproductive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 97.69 211/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.16.38.11] CASRLRSSRW#YW out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccagctccagggaagggctggagtgggtttcatGacattagtGagtagtagtagtaccatatactacgcagactctgtgaagggccgaGttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttcccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6792 JY8QFUQ01BC26X productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 6793 JY8QFUQ01BDS3U unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEEGCYWSLL##DHW out-of-frame + stop codons in FR2-IMGT at codon 46 of V-REGION: 'TC' (2 nucleotides at position 50 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'CG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccagggtTCccagggaaCGgggcgtggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggctgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6794 JY8QFUQ01COHJN No results 6795 JY8QFUQ01ABSUS productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tctggaattcagcttcagtacctataacatgaactgggtccgccaggctcCcagggaaggggctggantgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6796 JY8QFUQ01DLQUC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtgGgtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6797 JY8QFUQ01DMH7A No results 6798 JY8QFUQ01AKG6U productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 867 89.72 192/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFNDW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgaaagagtctctggttcggggagtcatctcatactactttaatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6799 JY8QFUQ01AEPA7 No results 6800 JY8QFUQ01B1PJB unproductive Homsap IGHV3-72*01 F 1073 98.64 218/221 nt 98.19 217/221 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.16.38.11] CLRPPRYD#PG out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6801 JY8QFUQ01BCE7T unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga 6802 JY8QFUQ01BKYGD productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 735 81.74 179/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgggtggttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6803 JY8QFUQ01CWFXN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ1*01 F 107 67.31 35/52 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CLRPPRYDPW# out-of-frame - in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctgggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6804 JY8QFUQ01AD84I productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + tctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgctggtccagggcttcttcc 6805 JY8QFUQ01A7STL productive (see comment) Homsap IGHV4-59*02 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARMPPGGVHFDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'GC' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift); tctccggtgcctccgtgagtagtgactactggagctgggtccggGCagtcccccaggaaaggggctggagtggattggatatatctattccactgggagcaccaactacaacccctccctcaagagtcgactcaccatgtcactggacacgcccaagaacgagttctccctgaaactgagctctgtgacagctgcggacacggccgtctatttttgtgcgagaatgcccccgggaggtgtccactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6806 JY8QFUQ01AQ96Q No results 6807 JY8QFUQ01A9BDW No results 6808 JY8QFUQ01DVVUT No results 6809 JY8QFUQ01CWF86 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 111 58.62 51/87 nt 57.47 50/87 nt 5 X X 5.X.X [24.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggttcttcttatgattattcaaggtgaatccaga 6810 JY8QFUQ01C1MUW productive Homsap IGHV3-7*01 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [0.17.38.11] CATSPFTVTTGKDAYW in-frame - tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6811 JY8QFUQ01C5YDT unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6812 JY8QFUQ01A2MA0 No results 6813 JY8QFUQ01BFQYE productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKLTYYDVGDYW in-frame + ctctggattcacctttgatgatcatgccatgcactgggtccggcaagctccagggaagggcctagagtgggtcgcgggtattacttggaatagtggtcacatagtctatgcggactctgtgaagggccgattcaccatctccagagacaacacgaagaactccctctatctgcagatgaacagtctgaccgctaaagacacggccttatattactgtgccaaactcacatattacgatgttggtgattattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 6814 JY8QFUQ01ACUDH unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F 617 88.96 137/154 nt 8 8 X 8.8.X [1.17.17.X] null - No rearrangement found tctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggcttcttccc 6815 JY8QFUQ01CE2ZP No results 6816 JY8QFUQ01DFNQ1 productive (see comment) Homsap IGHV3-23*05 F 799 86.38 184/213 nt 85.45 182/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 7 7 9 7.7.9 [1.17.38.11] CTREVGATDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6817 JY8QFUQ01B7H4M No results 6818 JY8QFUQ01AKKUR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tccggaattcagtttcagtacttataacatgaattTgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6819 JY8QFUQ01C1731 productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 6820 JY8QFUQ01AB1YG No results 6821 JY8QFUQ01B5191 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 6822 JY8QFUQ01ARJZM No results 6823 JY8QFUQ01C3WEI productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 6824 JY8QFUQ01ARC0B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6825 JY8QFUQ01AWT03 productive (see comment) Homsap IGHV3-7*01 F 752 93.06 161/173 nt 92.49 160/173 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.23.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 71 of V-REGION: 45 nucleotides (from position 120 in the user submitted sequence), (do not cause frameshift) cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6826 JY8QFUQ01BSDSX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.83 207/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6827 JY8QFUQ01CH3N8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6828 JY8QFUQ01AJLRE No results 6829 JY8QFUQ01A346T productive Homsap IGHV3-66*02 F 889 91.08 194/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + tctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctaaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6830 JY8QFUQ01BSUVD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - gtctggattcacctccagtacctatggtatgctctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctccttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6831 JY8QFUQ01C3KRL No results 6832 JY8QFUQ01DEI0V productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 925 90.99 202/222 nt 90.09 200/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagtggtcgCttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattAgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6833 JY8QFUQ01DINBU unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 6834 JY8QFUQ01CT2XT unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1029 98.13 210/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [0.17.38.11] CARGPPGGGSYYA#FDYW out-of-frame + tggatacaccttcaccagctactatatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtaccacaaactacgcacagaagttccagggcagagtcaccatgactagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggactcggccgtgtattactgtgcgagaggaccccccggtggcgggagctactacgccattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttct 6835 JY8QFUQ01DFC7X No results 6836 JY8QFUQ01CO2F0 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDRLGSCSGASCPVYYFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtgattcctcctggacctggatccgccagtacccagggaagggcctggagtggattgggtacatctctggcagtgggggActcctactccaacccggccctcaagagtcgagttaccatatcagtggacacgtctaagagccagttcttcctggaactgagttctgtgactgccgcggacacggccgtctattactgtgcgagagatcggctgggatcttgtagtggggctagctgccccgtctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg 6837 JY8QFUQ01BPLO0 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6838 JY8QFUQ01BUQ4R unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6839 JY8QFUQ01C8QAM No results 6840 JY8QFUQ01CHAWC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6841 JY8QFUQ01AYC69 No results 6842 JY8QFUQ01AS54C productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6843 JY8QFUQ01CKEU6 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6844 JY8QFUQ01BY164 unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-13*01 F 3 X X X X.X.X [X.X.28.11] CVKDRKGSNWYYFEN# out-of-frame + Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactgggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6845 JY8QFUQ01BFOI5 No results 6846 JY8QFUQ01DL6Z6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctacaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6847 JY8QFUQ01BJLUL No results 6848 JY8QFUQ01C589C unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 6849 JY8QFUQ01BCNLI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca 6850 JY8QFUQ01CRCG6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6851 JY8QFUQ01CC3QM unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNG#DFW out-of-frame + tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacgggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6852 JY8QFUQ01BEVA6 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 614 96.95 127/131 nt 96.18 126/131 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 X 9 8.X.9 [1.3.31.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 39 in the user submitted sequence), (do not cause frameshift) cgtctggattcaccttcaggagctattggatgagctggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6853 JY8QFUQ01C2LOK productive Homsap IGHV3-7*01 F 922 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - ctctggattcacctttagtaactattacatgagttgggtccgccaggcnccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6854 JY8QFUQ01AQEFQ No results 6855 JY8QFUQ01A7SLH productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARDSRHSASGSYSDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6856 JY8QFUQ01AIXP3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 846 88.02 191/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDWSGYARYDAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcggtgcctacggcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcattcgttaatagtgtaagtagtcacatatattacgcagactcagtgaggggccgattcaccatctccagagacaacggcgagaactccgtttatctgcaaatgtacagcctgagagccgaagacacggctacatactactgtgtgagagatagtgactggtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6857 JY8QFUQ01AYSB5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 7 13 8.7.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 2 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6858 JY8QFUQ01C8D0M productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 796 85.65 185/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6859 JY8QFUQ01CUQW4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6860 JY8QFUQ01DAAIL productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6861 JY8QFUQ01A3IMB productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 175 75.81 47/62 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARAVGQRGYDGTDLW in-frame + ctctggattcatgttcagcagttattggatgagctgggtccgccaggatccagggaaggggctggagtgggtggccaatataaacgaagaaggaagtgagaaatattatgtggactctgggaagggccgattcaggatctccagagacaacgccaagaattccgtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagcagtggggcagcgaggctacgacggtacagacctctggggccaagggaccacggtcatcgtctccacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6862 JY8QFUQ01CVI9D productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6863 JY8QFUQ01C95KI productive Homsap IGHV1-2*02 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtatattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6864 JY8QFUQ01DCDOK No results 6865 JY8QFUQ01BGOI8 productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6866 JY8QFUQ01CIG2U No results 6867 JY8QFUQ01CS4IY No results 6868 JY8QFUQ01BH3Y1 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 853 89.2 190/213 nt 87.79 187/213 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.37.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) ctctgacttaagcgtcagtgacaattacGatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatGactacgcagagtccgtgaagggccgattcgcgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6869 JY8QFUQ01CF60W productive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6870 JY8QFUQ01BXDWI productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6871 JY8QFUQ01AVPMG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 956 92.76 205/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 6872 JY8QFUQ01DSPRR unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6873 JY8QFUQ01BQ91P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6874 JY8QFUQ01AXDDD No results 6875 JY8QFUQ01DIZ9U productive (see comment) Homsap IGHV3-7*01 F 821 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [3.17.38.11] CAREQSSRGYPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); ctccggaatttccaatttttgggngacttttggttgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAagcaagatggaagtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatatccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6876 JY8QFUQ01CPWP1 No results 6877 JY8QFUQ01AV8GT productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccaggctcttccccca 6878 JY8QFUQ01B21O0 productive (see comment) Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6879 JY8QFUQ01DQRNC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 996 95.0 209/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame + aacctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaact 6880 JY8QFUQ01AG024 productive (see comment) Homsap IGHV3-7*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 6 8.8.6 [1.17.37.11] CVKSIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggattcacttttagcagtttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggcttcttccccca 6881 JY8QFUQ01AB5UK No results 6882 JY8QFUQ01AVBOK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 308 61.39 124/202 nt 8 8 X 8.8.X [1.17.32.X] null - No rearrangement found Low V-REGION identity (61,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6883 JY8QFUQ01CN8F8 No results 6884 JY8QFUQ01AOUA3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6885 JY8QFUQ01AW2LQ productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 6886 JY8QFUQ01AN2J8 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + tctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagccacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 6887 JY8QFUQ01CK8OV No results 6888 JY8QFUQ01ASU8O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6889 JY8QFUQ01CT3CN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6890 JY8QFUQ01C6S8S No results 6891 JY8QFUQ01CH9SI unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREVKYGDDTG#WFDPW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); tctggattccccatcagtgGgctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaagggccgattcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattactgtgcgagagaggtgaaatacggtgacgacacggggggtggttcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6892 JY8QFUQ01BANC8 No results 6893 JY8QFUQ01DUVAT unproductive Homsap IGHV4-39*03 F 930 90.99 202/222 nt 90.09 200/222 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-8*01 F 2 10 7 X 10.7.X [2.17.38.11] CTREGPYYYGMDV## out-of-frame - in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); tgtctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtGccctcaagagtcCgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6894 JY8QFUQ01A5PWS productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 975 95.33 204/214 nt 94.86 203/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 7 7 18 7.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcagtggttacactggaactggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6895 JY8QFUQ01AAWUE No results 6896 JY8QFUQ01DABGE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CNLHPYGDSSDYW in-frame + ctctggactcaccttcagtcgcctctggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatagatagtgatgggaataacataatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaaaacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtaaccttcatccctacggtgactcctccgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6897 JY8QFUQ01A4XPO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD5-12*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARDGSAHSSIYHYYYGMDVW in-frame + ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtctcaaccattggtactagaggtagatccatatactacgcggactcagtgaagggccgattcaccacctccagagacaacgccaagaaatcactttatctggatatgcacagcctgagagccgaggacacggctatctattactgtgcgagagatggcagtgcacactcgtcgatctatcattactattacggcatggacgtctggggccaagggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtcgtcatcgcctgcctggtccagggcttcttcc 6898 JY8QFUQ01B8W2U productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6899 JY8QFUQ01DCFU5 productive Homsap IGHV3-30*12 F, or Homsap IGHV3-33*05 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDLYCSGGTCSDYW in-frame + tctggattcaccttcagtcagtactggatgtactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggctgtctattactgtgcgagagacctatattgtagtggtggtacctgcagcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6900 JY8QFUQ01AYD6Y unknown (see comment) Homsap IGHV3-7*02 F 114 59.52 50/84 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6901 JY8QFUQ01DFUCH productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame + ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6902 JY8QFUQ01AC5KS No results 6903 JY8QFUQ01CD4VE unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGV*QWL##DFDCW out-of-frame - stop codons ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6904 JY8QFUQ01BPD81 No results 6905 JY8QFUQ01C5EHB productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6906 JY8QFUQ01ATRRJ unproductive Homsap IGHV3-48*01 F 963 94.01 204/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.16.38.11] CARDGDSTVL#DYW out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'CA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) cctctggattGcacctttagtaacCAtttgggatgaactgggtccgccaggctccgggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaaagactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagacggggactctacggtactcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6907 JY8QFUQ01A0XE3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 6908 JY8QFUQ01DRSTV No results 6909 JY8QFUQ01B39P6 No results 6910 JY8QFUQ01B4O50 productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgcgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6911 JY8QFUQ01CF31P unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F or Homsap IGHV3-9*01 F or Homsap IGHV3-9*03 F 83 51.54 67/130 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcacctttagtgattatagaatgaattgggtccgccaagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 6912 JY8QFUQ01CC8BY unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 6913 JY8QFUQ01AA63Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDAVGLTRLFGDW in-frame + ctctggatttgtctttagtagatatgccatggcctgggtccgccaggctccagggcaggggctggagtgggtcgccagtattggcgggagtggtgataacacatactacgcggactccgtgaagggccggttcaccatctccagagacaactccaataacaaactgtttctgcaaatggacagtttgcgagccggggacacggccagatatttctgtgcgaaagatgcggtgggacttacccgactctttggtgactggggccagggaaccgtggtcagcgccgcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgccctggtccagggcttcttccccca 6914 JY8QFUQ01ATUUQ productive (see comment) Homsap IGHV3-15*05 F 924 91.36 201/220 nt 90.0 198/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD6-13*01 F 1 7 10 10 7.10.10 [1.16.38.11] CATYSNKWSVFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 94 of V-REGION: 'A' (1 nucleotides at position 188 to 188 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctggattcaattcactaacgcctggatgagctgggtccgccaggctccggtaaggggctggagtgggttggccatattaaagccaacactgatggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcgagagatgattcaaaagccacagtatatctgcagatgagcattAcggaaaaccgaagacacagccgtgtatttctgtgcaacctatagcaacaagtggagtgtcttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6915 JY8QFUQ01CG8LN unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYFEF## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 6916 JY8QFUQ01A1ID6 No results 6917 JY8QFUQ01C1U8F unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtcggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6918 JY8QFUQ01DINPB productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 852 87.73 193/220 nt 86.82 191/220 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) cagcctctggattcagtttagtacacatggcatgaactAgggtccgccaggctccagggaatgggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6919 JY8QFUQ01AL1GZ productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1007 94.64 212/224 nt Homsap IGHJ6*01 F (see comment) 180 76.19 48/63 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtggctctgctatgcactgggtccgccaggtttccgggaaagggctggagtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatttggaaatgaacagtttgaagagggaggacacggccgtgtattactgtgtgagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggtcaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 6920 JY8QFUQ01AM69R No results 6921 JY8QFUQ01BHL2X No results 6922 JY8QFUQ01DVCZ5 No results 6923 JY8QFUQ01CMFO6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6924 JY8QFUQ01A0P50 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 2 10 7 X 10.7.X [1.17.38.11] CARLTDWWG##FDHW out-of-frame + stop codons tctctggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtggggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 6925 JY8QFUQ01ANGDO unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 191 60.77 79/130 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 6926 JY8QFUQ01DCT1Z unknown (see comment) Homsap IGHV3-23*05 F 108 56.57 56/99 nt 8 6 X 8.6.X [1.17.X.X] null + No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 6927 JY8QFUQ01A9XR5 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 6928 JY8QFUQ01DKX3B No results 6929 JY8QFUQ01CCW31 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6930 JY8QFUQ01AIVRQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatCgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6931 JY8QFUQ01DKN3S unproductive Homsap IGHV4-61*02 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-16*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREHSSSIGGERELDS## out-of-frame + tgtctggtggccccatcagcagtagtggcttcgcctggacctggatccggcagaccgccgggaagggactggagtggatcggacgtgtttatggtagtgggaataccaattacagtccttccctccagagtcgagtcaccatatcagtagagacgtccaagaatcagttctccctgaggttgacttctgtgaccgccgcagacacgggcctatattactgtgcgagagaacatagtagttcgattggcggagagagagaacttgactcctggggccagggaacccgaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 6932 JY8QFUQ01B4XES productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6933 JY8QFUQ01DJ0QP unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 854 95.19 178/187 nt 94.65 177/187 nt 8 7 X 8.7.X [1.16.29.X] null + No rearrangement found in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctgggttcaacgtcagtagcgactacatgagctgggtccgccaggctccagggaaggggctggagtggtctcagttatttatggaggtggtagtacatactacgcagactccgtgaagggccgattcaccatgtccagagacaattccaagaacacggtgtatcttcagatgaatagcctgagag 6934 JY8QFUQ01BBKM0 No results 6935 JY8QFUQ01BMHXX unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.43 191/216 nt Homsap IGHJ2*01 F (see comment) 30 66.67 10/15 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttcccgaaccggtgacggtgtcgtggaac 6936 JY8QFUQ01B441S productive (see comment) Homsap IGHV3-7*01 F (see comment) 725 81.65 178/218 nt 80.73 176/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); cctctggattcacctttagaagctatgccatgagttgGggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatactTttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6937 JY8QFUQ01DMDYG No results 6938 JY8QFUQ01AL76Y No results 6939 JY8QFUQ01CSOSY productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 6940 JY8QFUQ01B4PX2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 6941 JY8QFUQ01BLIGP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6942 JY8QFUQ01C5UV3 No results 6943 JY8QFUQ01ANVMV unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 105 100.0 21/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcactttcagtaa 6944 JY8QFUQ01AY6XT productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6945 JY8QFUQ01C2W2V No results 6946 JY8QFUQ01B4IND No results 6947 JY8QFUQ01BED94 No results 6948 JY8QFUQ01CO5FZ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 202 95.45 42/44 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found ctctggattcaccttcagtagctactggatgcactgggtcccca 6949 JY8QFUQ01ANPDB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 6950 JY8QFUQ01BY7G4 No results 6951 JY8QFUQ01AULA5 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6952 JY8QFUQ01A1J72 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARVFSGVAAPPDSW in-frame - ctctggaatttcccttcaccagttactggatgcagtgggtccgccaagctccagggaaggggctggtctgggtctcacttagtaatagtgatgggagcactactacctacgcggacgccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatcttcaaatgaatcatctgagagtcgaggacaccgctgtatatttctgtgcgagagttttcagtggtgtcgctgctcccccggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6953 JY8QFUQ01B4ZSG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggcccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggaactc 6954 JY8QFUQ01CAGIU No results 6955 JY8QFUQ01CXWLV No results 6956 JY8QFUQ01BOO7X productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6957 JY8QFUQ01BQMCE No results 6958 JY8QFUQ01DF7SD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 916 90.54 201/222 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [3.17.38.11] CARGHSYYVSSGPDY## out-of-frame - gcagcctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6959 JY8QFUQ01AZ4SQ No results 6960 JY8QFUQ01ACVY4 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame - ctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6961 JY8QFUQ01DADPQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 6962 JY8QFUQ01CB0JI unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6963 JY8QFUQ01BKVAE productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6964 JY8QFUQ01BHBOZ No results 6965 JY8QFUQ01C7CUA No results 6966 JY8QFUQ01AEDSZ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 130 71.7 38/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcacccctggtcactgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 6967 JY8QFUQ01B4OHV No results 6968 JY8QFUQ01C1V23 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6969 JY8QFUQ01CQ6HE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARVRGGLSSGWYESLDYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagttcgaggaggtcttagcagtggctggtacgagtctcttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccctt 6970 JY8QFUQ01CVKGA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccaccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccgtgacggtgtcgtggaactcag 6971 JY8QFUQ01AF8SZ productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [2.17.38.11] CVGVGVGSSVSFQYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); gcctctggattcactgtcaataacaactacatggGgttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacactttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 6972 JY8QFUQ01C6LUZ No results 6973 JY8QFUQ01C8AP7 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 135 77.78 35/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgcca 6974 JY8QFUQ01AND8W productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift); tctctggtgGggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6975 JY8QFUQ01BEKRO productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 849 87.0 194/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CAISSDFYSTGYW in-frame - ctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6976 JY8QFUQ01CS4ZH unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6977 JY8QFUQ01BRRHQ No results 6978 JY8QFUQ01A5ZX6 productive Homsap IGHV1-2*02 F 804 86.45 185/214 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD3-16*02 F 2 8 8 15 8.8.15 [0.17.38.11] CARHFCDTNDVCDFDIW in-frame + tggatacagcttcaccgacttttacattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaaatggtggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggagatgagcaggctgagatctgacgacacggccatttattactgtgcgagacatttttgtgacaccaacgacgtctgtgattttgatatctggggccaggggacaaaggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 6979 JY8QFUQ01DIQBL No results 6980 JY8QFUQ01CF6S7 productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 393 91.49 86/94 nt 90.43 85/94 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 21 to 25 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6981 JY8QFUQ01CA8X1 No results 6982 JY8QFUQ01A1RQZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6983 JY8QFUQ01DW561 No results 6984 JY8QFUQ01BXLHS productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6985 JY8QFUQ01C1UBU No results 6986 JY8QFUQ01C0A57 unproductive Homsap IGHV3-7*01 F 832 86.7 189/218 nt 83.94 183/218 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRPGGWALDY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'T' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'ATG' (3 nucleotides at position 62 to 64 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); ctcctggattcaGtttttagtgacttttggatgcgActgggtccTgccaggcnccaggggaATGggggctggagtgggtggGcccacntgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacgGgctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactgggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6987 JY8QFUQ01DCQ1T No results 6988 JY8QFUQ01DESYR productive (see comment) Homsap IGHV4-39*03 F 920 90.91 200/220 nt 90.0 198/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [2.16.38.11] CTREGPYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccaggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtGccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6989 JY8QFUQ01BIDBG unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 6990 JY8QFUQ01C9ZA6 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGGFGAR#DYW out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggttttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6991 JY8QFUQ01AFCRV productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gtctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6992 JY8QFUQ01AE5R0 No results 6993 JY8QFUQ01DBYPZ unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 6994 JY8QFUQ01DMVTY No results 6995 JY8QFUQ01BKSTZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaaggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 6996 JY8QFUQ01BPGKK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 6997 JY8QFUQ01A7BGY productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 101 of V-REGION: 'A' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctAgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 6998 JY8QFUQ01CW0ME productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 6999 JY8QFUQ01AS1T0 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + ctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 7000 JY8QFUQ01BEHCJ No results 7001 JY8QFUQ01A1BXA No results 7002 JY8QFUQ01B7SR3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7003 JY8QFUQ01C3KDY productive (see comment) Homsap IGHV3-13*01 F 898 91.55 195/213 nt 91.08 194/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [1.17.37.11] CAREVTRLTVPYYLYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 200 in the user submitted sequence), (cause frameshift) ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccggggacacgctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaangtggtcgtcgcatgcctggtccagggcttcttcccccaa 7004 JY8QFUQ01DG9VD No results 7005 JY8QFUQ01AB51E productive Homsap IGHV3-48*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame - ctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7006 JY8QFUQ01AGUFW No results 7007 JY8QFUQ01BYQPY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7008 JY8QFUQ01CR7U0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 822 87.38 187/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.37.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7009 JY8QFUQ01DSDF6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactactcccgaccggtgacgtgtcgtggaactcag 7010 JY8QFUQ01BS28G No results 7011 JY8QFUQ01DTJ0Q unknown (see comment) Homsap IGHV1-2*03 F 83 57.35 39/68 nt 55.88 38/68 nt 8 X X 8.X.X [0.13.X.X] null - No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) tggatacaccttcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7012 JY8QFUQ01BRUUS productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 912 90.13 201/223 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 10 14 8.10.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtggctctgctatgcactgggtccgccaggtttccgggaaagggctggagtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7013 JY8QFUQ01CDPNO No results 7014 JY8QFUQ01BQHEC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 493 83.57 117/140 nt 82.86 116/140 nt 8 8 X 8.8.X [1.16.12.X] null - No rearrangement found Low V-REGION identity (83,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 7015 JY8QFUQ01AKNKF unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7016 JY8QFUQ01C31PA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7017 JY8QFUQ01AI5J2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 925 92.96 198/213 nt 92.02 196/213 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaggaagggactgcagtggattggttacatctatcacCagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7018 JY8QFUQ01BRQVZ productive (see comment) Homsap IGHV3-9*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) ctctggattcactttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7019 JY8QFUQ01BRXHG unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F 137 52.72 97/184 nt 8 7 X 8.7.X [0.17.28.X] null - No rearrangement found ctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7020 JY8QFUQ01A3OS9 productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc 7021 JY8QFUQ01AQT5C productive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [2.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7022 JY8QFUQ01A1QIB No results 7023 JY8QFUQ01AUB4Z No results 7024 JY8QFUQ01CUXQ0 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7025 JY8QFUQ01BU35B productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift); tctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacaGcggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7026 JY8QFUQ01BL0B1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.49 179/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDRPAGKAEGYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttagtgattatgccatggcctgggtccgccaggctccagggaaggggctggaatgggtcggaagtattaatctcagtgttgatgacacatattacgcagcctccgtgaggagtcgcttcaccgtctccagagacaattccaagaacaccttctatttgcacatggccagcctgagagccgaagacacggccatatattattgcgcgaaagatcggccagccggaaaggctgaggggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7027 JY8QFUQ01BV2B3 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7028 JY8QFUQ01A3ZBL No results 7029 JY8QFUQ01BIDDX No results 7030 JY8QFUQ01A1UXZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccccctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 7031 JY8QFUQ01BPC6B No results 7032 JY8QFUQ01AFU74 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7033 JY8QFUQ01AQ25R productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 870 88.64 195/220 nt 87.73 193/220 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [1.16.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 31 of V-REGION: 'TGC' (3 nucleotides at position 20 to 22 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) tctcgggtgactccctgagTGCcagtagtagtttctactggggctgggccgccagcccccagggaagggactggagtggattgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccagaaccaggtctccctgacgttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7034 JY8QFUQ01BRGSI productive Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARVGATLSFDVW in-frame + ctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7035 JY8QFUQ01BQ9KW productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 7036 JY8QFUQ01A6UEX productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7037 JY8QFUQ01BMUUJ productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggAagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7038 JY8QFUQ01CVWSV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7039 JY8QFUQ01DGC1Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7040 JY8QFUQ01BDF0B No results 7041 JY8QFUQ01AQ3T9 productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame + ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7042 JY8QFUQ01AVH5A No results 7043 JY8QFUQ01AGKQB productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD2-15*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAKGGGNGDLDYWG in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7044 JY8QFUQ01BBZW6 No results 7045 JY8QFUQ01BMJGI productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWHYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggcactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7046 JY8QFUQ01CRJXJ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 6 15 8.6.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataggggaggaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 7047 JY8QFUQ01B5EMZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7048 JY8QFUQ01C1LP7 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 7049 JY8QFUQ01A3U1I productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaagggttcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcaatgcctggtccagggcttcttcccc 7050 JY8QFUQ01AE6UZ productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7051 JY8QFUQ01B2R53 unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 7052 JY8QFUQ01BNMS9 productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYHYDTFGDYW in-frame + ctctggattcacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaatgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcaatatatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattatcattatgacaccttcggcgactattggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 7053 JY8QFUQ01DP55Y productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-14*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARHLQYNRHGFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 175 to 175 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtagtcattactactggggctggatccgccagaccccaggaaAaggggctggagtggcttgggacaatctattatagcggaagcgcctacatcaacccgtccctcaagagtcgagtcaccatttccgttgacatatctaagaaccagttctccCctgaggctgacctctgtgaccgccgcagacacggctgtctattactgtgcgagacacctgcaatataatcgacatggttttgatttctggggccaggggacaacggtcaccgtctcttcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7054 JY8QFUQ01CIGT5 No results 7055 JY8QFUQ01AG3IU productive Homsap IGHV3-9*01 F (see comment) 789 84.55 186/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7056 JY8QFUQ01BB0BB unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7057 JY8QFUQ01CHKWD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 853 89.2 190/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [X.17.38.11] CARLGQLALDYW in-frame - gggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7058 JY8QFUQ01C0MXG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 501 84.78 117/138 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaact 7059 JY8QFUQ01BWVM6 productive Homsap IGHV3-11*01 F 938 93.87 199/212 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [X.17.38.11] CARDLQLGDDSGFSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gattcaccctcagtgactactacatgacttggatccgccaggctccagggaaggggctggagtgggtttcgtacattagtagtctcactagttccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgagagatcttcagctgggggatgatagtgggttttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7060 JY8QFUQ01APENB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7061 JY8QFUQ01A4BVQ No results 7062 JY8QFUQ01CHFPQ unknown (see comment) Homsap IGHV4-61*02 F (see comment) 707 80.73 176/218 nt 80.28 175/218 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7063 JY8QFUQ01CQFLG productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgntgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 7064 JY8QFUQ01AF76F No results 7065 JY8QFUQ01DW1F3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7066 JY8QFUQ01AMBQU No results 7067 JY8QFUQ01AMJ07 productive (see comment) Homsap IGHV3-33*05 F 840 88.32 189/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'N' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagtNtttggcatctggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7068 JY8QFUQ01C1OYL productive (see comment) Homsap IGHV1-18*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD1-20*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tggttacacctttactacctatgGgcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatgataatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacggccgtatattattgtgcgcgagtaattcgaaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7069 JY8QFUQ01AR065 No results 7070 JY8QFUQ01BOHG3 No results 7071 JY8QFUQ01B4Y1N productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame + tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7072 JY8QFUQ01C6FUD productive Homsap IGHV3-33*02 F, or Homsap IGHV3-33*03 F 148 65.43 53/81 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 X X 14 X.X.14 [X.X.27.11] CATDDSNGWDEVADYW in-frame - gcctctggattcaccttcagctcccattggatgagctggatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7073 JY8QFUQ01A8S53 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - gtctggattcacatttagaagctattccatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7074 JY8QFUQ01AJNWH unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt 93.27 208/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtaacgcctggatgatctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagaccaaagctgatggtgcgacaacagactactctgcacccgtgagaggcagattcatcatctcaagagatgattcaaaaaaTcatggcgtttctgcaaatgaacagcctgaaaaccgaggacacagccctttattactgtacctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccccta 7075 JY8QFUQ01A1AL3 productive Homsap IGHV4-61*02 F (see comment) 596 74.66 165/221 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARECSNSKVGPRALDSLG in-frame + Low V-REGION identity (74,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagcccgccgggaagggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctatatttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattccctgggggccccgggaagtctggtcaccgtatcatcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7076 JY8QFUQ01DRQBM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7077 JY8QFUQ01AD74T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame + ctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7078 JY8QFUQ01BVWJB No results 7079 JY8QFUQ01B89F3 productive Homsap IGHV3-11*01 F (see comment) 764 84.19 181/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [0.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7080 JY8QFUQ01AFRV4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 7081 JY8QFUQ01CN5CY No results 7082 JY8QFUQ01BLUX0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 7083 JY8QFUQ01BP937 No results 7084 JY8QFUQ01ASAFA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7085 JY8QFUQ01CWIEU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 7 15 8.7.15 [0.17.38.11] CAKVYTGAWGDPNFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) ctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtactttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7086 JY8QFUQ01ASX49 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 400 77.61 104/134 nt 76.12 102/134 nt 7 6 X 7.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7087 JY8QFUQ01AKWRV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7088 JY8QFUQ01AIQZV productive Homsap IGHV3-48*01 F 963 94.01 204/217 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARVGATLSFDVW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7089 JY8QFUQ01BPR4U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 707 80.73 176/218 nt 80.28 175/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARYRVGDSLYYGLDGW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 90 to 92 in the user submitted sequence), (do not cause frameshift); cctctggattcattttagaaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7090 JY8QFUQ01CCNJV productive Homsap IGHV3-13*01 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - agcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattgacactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7091 JY8QFUQ01BTRXA No results 7092 JY8QFUQ01CY676 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 903 91.59 196/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'GA' (2 nucleotides at position 108 to 109 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaggaagggactgcagtGggattggttacatctatcacagtgggagcaccaactacGAacccctaccctcgagagtcgagtctccaGtttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7093 JY8QFUQ01DHXAX No results 7094 JY8QFUQ01C9NLW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARAAGAGGKGGMDAW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcgccttcagtacttatggcataagttgggtccgccaggctccagggaaggGggctggagtgggtctcatccatcagtagtggcggtggttacatacactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaattcagtgcatctggaaatgaacatcctgagagccgaggacacggctgtgtactattgtgcgagagcggccggcgcaggaggtaaaggcggtatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7095 JY8QFUQ01C8NA6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 497 84.17 117/139 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,17% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 7096 JY8QFUQ01APNF7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactcanttccccgaaccggtgacggtcgtgcgtggaactcag 7097 JY8QFUQ01BBN1F productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7098 JY8QFUQ01A9JBF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CGKPIVGATGREMPVSL# out-of-frame + ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttccctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 7099 JY8QFUQ01DQ9J1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1036 97.26 213/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7100 JY8QFUQ01BE9YX No results 7101 JY8QFUQ01CE6FY No results 7102 JY8QFUQ01C315L productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggacatccag 7103 JY8QFUQ01BT8R0 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 80 51.13 68/133 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7104 JY8QFUQ01C61HC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaggggcgtggagtggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7105 JY8QFUQ01AUMIQ productive Homsap IGHV3-13*01 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7106 JY8QFUQ01C92K1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7107 JY8QFUQ01B043H No results 7108 JY8QFUQ01A889C No results 7109 JY8QFUQ01A9KO3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 7110 JY8QFUQ01CDKHU productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.16.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggctggagtggatggggatcatctatcctggtaactctgagaccaAaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7111 JY8QFUQ01CA2BM No results 7112 JY8QFUQ01BIIYS No results 7113 JY8QFUQ01CE8KX unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGAGAEGKGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); ctctggattcaccttcCaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7114 JY8QFUQ01BQQQR productive Homsap IGHV1-69*04 F, or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAIPFSSSSAWFDPW in-frame + tggaggcaccttcagcagctatgtcatcagctggctgcgacaggcccctggacaagggcttgagtggatgggacatgtcattcctatgtttggtgtatctaacctcgcgcagaggttccagggcagagtcacaataaccgcggacacatccacgaccacagcctacatggaggtgaccaggctgagatctgaagacacggccgtctattattgtgccataccattcagcagctcgtcggcctggttcgacccctggggccagggaaccctggtcacgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7115 JY8QFUQ01A27VW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 103 58.75 47/80 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7116 JY8QFUQ01AIUE1 No results 7117 JY8QFUQ01DERL0 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7118 JY8QFUQ01BD4SW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccgaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtcgacggtgtcgtggcaactcag 7119 JY8QFUQ01BCD33 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7120 JY8QFUQ01ACU3P unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 890 88.39 198/224 nt 87.5 196/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [2.17.37.11] CTADVPSPLAQ#DFW out-of-frame - in FR3-IMGT at codon 76 of V-REGION: 'A' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) gcctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattAcgtcatctcaagagacgattcaaaaaaaggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7121 JY8QFUQ01ARGUC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 7122 JY8QFUQ01AXW3W unknown (see comment) Homsap IGHV3-7*02 F 177 78.95 45/57 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found tctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttcccca 7123 JY8QFUQ01BFUH9 unknown (see comment) Homsap IGHV1-2*03 F 83 57.35 39/68 nt 55.88 38/68 nt 8 X X 8.X.X [0.13.X.X] null - No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) tggatacaccttcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7124 JY8QFUQ01CCYZD productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.16.38.11] CVRLDYYGSGSSYSGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) gtctggtggctccatcagtggtactccttactactggggctggatccgccagcccccaggtaagggctggagtggattgggcatgtatatcacagagggaccacctactacaacccgtccctcaagagtcgagtcgccatatccgtagacacgtccgagaaccggttctccctgcagttgaactctgtgaccgccgcagacacggctgtatattactgtgtgagactggattactatggttcgggaagttcttatagtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 7125 JY8QFUQ01BOLNO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7126 JY8QFUQ01BHQVJ unproductive (see comment) Homsap IGHV4-61*08 F 848 87.33 193/221 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-15*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARDFGYCSGENCNVP* in-frame + stop codons tctctggtgactccgtcagtagtggtgactattactggacgtggatccggcagctcccagggaagggactggagtggattggatatatgacttccggtgggacaaccaagtacaattcctccctcaagagtcgagccaccatatcagtggacacgtccaagaatcaactgtccctgacgttgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatttcggatattgtagtggtgagaactgcaatgtaccttgaggccagggaaccctggtcaccatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7127 JY8QFUQ01B508J productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGPGGGWYAEQW in-frame + gtctggattcagtttcagtgactatgccatgcactgggtccgccagactccaggcaaggggctggagtgggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7128 JY8QFUQ01CNTYE No results 7129 JY8QFUQ01BXS1D productive Homsap IGHV4-34*06 F (see comment) 701 80.84 173/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 14 8.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tccatggtgggtccctcaggggttacccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 7130 JY8QFUQ01CP3RW No results 7131 JY8QFUQ01BMZ10 unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 879 89.09 196/220 nt 87.73 193/220 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [2.17.38.11] CARVGTFNWF#PW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); ggcctctggattcaGattttgcagattatggcatgggctgggtccgccaacttccagggaaGggggctggaatgggtcggtggtgttaattggaatTgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7132 JY8QFUQ01CHAMB No results 7133 JY8QFUQ01BBC3I No results 7134 JY8QFUQ01C5AWT productive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 7135 JY8QFUQ01C9L8S unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 7136 JY8QFUQ01DHC2K No results 7137 JY8QFUQ01B4AIN productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 831 87.38 187/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + tggaggctccttcagcatgtatgacatcagctgggtgcgacaggcccctgggcaagggcctgagtggatgggagcgatcaaccctgtctttcgtatagcgaattacgctcagaggttccagggtagagtcaccattatcgcggacgactctacgagcacagcctacatggagctggacagcctgacgtctgaggacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 7138 JY8QFUQ01BLJ3D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7139 JY8QFUQ01CNG9Q productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctgggtcccacggggttcttcccccag 7140 JY8QFUQ01CQAMY productive (see comment) Homsap IGHV3-7*01 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 3 nucleotides (from position 12 in the user submitted sequence), (do not cause frameshift) cctctggattactttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7141 JY8QFUQ01CEPL7 productive Homsap IGHV2-5*02 F 1062 93.03 227/244 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CGHIRAELSTACHALW in-frame + gaccctcacgctgacctgcaccttctctgggttttcactcgacactattggaatgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcacttatttattgggatgatgataagcgctacacctcatctctgaagaccagactcagcatcaccaaggacacctccaaaaaccaggtggtcctcacaatgactaacatggaccctttggacacagccacatacttctgtggacacattagggcggaacttagcaccgcctgccatgccttgtggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttcccc 7142 JY8QFUQ01CPVAW No results 7143 JY8QFUQ01C6Y2R productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPYNGGGYGAFDIW in-frame + ctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggacgtggtcatcgcctgcctggtccagggcttcttccccc 7144 JY8QFUQ01DPW6S productive Homsap IGHV3-11*01 F, or Homsap IGHV3-48*01 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame + cctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcatttatcactgataggggtagtacccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagcatgggaacgcggtcgtcgcatgcctggtccagggcttcttccccca 7145 JY8QFUQ01B2MWK No results 7146 JY8QFUQ01AM249 productive (see comment) Homsap IGHV3-30*13 F (see comment) 224 76.25 61/80 nt 75.0 60/80 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 X X 14 X.X.14 [X.X.26.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (76,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 87 of V-REGION: 12 nucleotides (from position 39 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcagtgactatcacatgtactggatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccttggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7147 JY8QFUQ01DNKS2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 2 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) gtctctggcgactccatcagtggtcactactggagctggtcagcagccccaggccaagggaGctgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7148 JY8QFUQ01CKYI5 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CAKEGDGSVIPSPVPEWQ#FDSW out-of-frame + stop codons Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttgacagccatgccatgcactgggtccgtcgggctccagggaaggggctggagtgggtctcggcagttagtggtggtggccattatacatactacgcgcgctccgtgaagggccgatttaccatatccagggacaattcccgaaacatggtgtatttggagatgactggcctgacagccgaggacacggccgtatattattgtgcgaaagagggagacggatcagtgatcccgtctcctgttcctgagtggcaaatttgactcctggggccagggaaccctggccacggtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccc 7149 JY8QFUQ01CUYQI productive Homsap IGHV3-21*04 F (see comment) 657 78.34 170/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7150 JY8QFUQ01C7DZ2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTKTRAFYYGSGSDGW in-frame + cctctggattcacctttagtagctatgccatcaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggcactacatactacgcagactccatgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtacaaaaactcgggcgttttactatggttcggggagtgatgggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7151 JY8QFUQ01BRAPP No results 7152 JY8QFUQ01CN5MD productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7153 JY8QFUQ01C48DS productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7154 JY8QFUQ01DW4VZ productive (see comment) Homsap IGHV3-48*02 F (see comment) 726 80.91 178/220 nt 80.0 176/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 27 of V-REGION: 'GA' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); agcctctggGAttcccccttcaatatatggagcatgaattgggtccgccaggctcCcggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7155 JY8QFUQ01BXDOJ No results 7156 JY8QFUQ01A8IP5 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 916 92.49 197/213 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CASQDYGEEGPDDD##FDIW out-of-frame - stop codons tctggtgcctccatcagtagttactactggagttggattcggcagcctccagggaagggactggagtggattgcttatatctcttacagtgggagggccaactacaacccctccctcaagagtcgagtcaccatgtcctcagacacgtccaagaaccaggtctccctgaagctgacgtctgtgaccgctgcggacacggccgtgtattactgtgcgagccaagactacggtgaagaggggccagatgatgatgccttttgatatctggggtcgagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7157 JY8QFUQ01C36E5 No results 7158 JY8QFUQ01DKHUQ productive (see comment) Homsap IGHV3-33*04 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD4-17*01 F 3 8 8 8 8.8.8 [1.16.38.11] CARDTFGTTG in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) atttggattccctttcagcgactatggcatgcactgggtccgccaggctccagacaagggactagaaatgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatacttttgggactactggggccaggggaacccaggtcatcgtctcttcagcctccaccaaggggcccatcggtcttccccctggcacctcctccaagagcactctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7159 JY8QFUQ01CY2QM productive (see comment) Homsap IGHV4-61*07 F (see comment) 736 83.1 177/213 nt 82.63 176/213 nt Homsap IGHJ2*01 F 175 81.13 43/53 nt Homsap IGHD3-9*01 F 2 8 7 12 8.7.12 [2.17.38.11] CAREATYYDAFDVW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01CY2QM ; 10 AA in Homsap_IGHV4-61*07), and low V-REGION identity (83,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 64 of V-REGION: 'CAAA' (4 nucleotides at position 98 to 101 in the user submitted sequence), (cause frameshift); gtctctggcggctccgatcgggagttactactggacctggatccggcagtctccagggaaggggctggagtggattggatatagccacagcagtgggCAAAaccaattataagtacccttccctcaagagtcgagtcaccatatcaatagacacgtccaagaaccagttctccctgcagctgacctctgtgaccgctgcggacacggccatatattcctgtgcgagagaagcaacttactatgatgccttcgatgtctggggccgtggcacccaagtcagtgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7160 JY8QFUQ01DWM6Q unproductive Homsap IGHV3-9*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKDWPSSGWSHFE#L out-of-frame - gcctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaagattggccgagcagcggctggtcccattttgaggcttgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7161 JY8QFUQ01AL5WH productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagaCgggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7162 JY8QFUQ01AYR54 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - tctggagttcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 7163 JY8QFUQ01BH2XD No results 7164 JY8QFUQ01CYD54 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7165 JY8QFUQ01BJL8P No results 7166 JY8QFUQ01AKY8Y productive (see comment) Homsap IGHV3-48*01 F (see comment) 744 83.89 177/211 nt 82.94 175/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) tggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7167 JY8QFUQ01CQX10 productive Homsap IGHV3-23*05 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKSTGHSGWYPFDNW in-frame + ctctggattcacattcagcaattatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtcgctgctattgatggcagtggtgaaagaactcactatgcagactccgaacagggccgcgtcaacatctctagagacaattccaagaacatgatatatgtgcaattgagcagcctgagagccgaggacacggccatgtattactgtgtgaagtccaccgggcacagtggctggtatccctttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttccttcccccga 7168 JY8QFUQ01AX6Q1 productive (see comment) Homsap IGHV3-30*07 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVTERGGGLLRYLDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagccatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggGgggttatatcatctgatggaagtaatgaatactatgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactgtgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7169 JY8QFUQ01CJ0EA productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKAYDDVLTSYYIAAFHYSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgccatgcattgggtccgccaggctccaggcaaggggccggagtgggtggcagttatatcatatgatggaagtcataaagactatgcagcctccgtgaagggccgattcaccatctccagagacaattccaagagtacgttgtatctgcaaatgaacagcctgagacctgaggacacggctttatattcctgtgcgaaggcatatgacgatgttttgacttcttattacatagcagcttttcattactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 7170 JY8QFUQ01BWAC8 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 289 65.16 101/155 nt 8 8 X 8.8.X [1.17.17.X] null + No rearrangement found Low V-REGION identity (65,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7171 JY8QFUQ01C8VGH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7172 JY8QFUQ01CMLZZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKHTLDYGPQYTMDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagagactatgtcatgagctgggtccgtcaggctccagggaaggggctggagtgggtctcaagtatcagtgatggaggtaatacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacgccctgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgaagcatacacttgactacggcccgcagtacactatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7173 JY8QFUQ01BI2OG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.37.11] CAKIHGSCSSTSC##NWFDPW out-of-frame + in FR3-IMGT, from codon 102 of V-REGION: 2 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtattactgtgcgaaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7174 JY8QFUQ01BKTDB No results 7175 JY8QFUQ01CWM9J No results 7176 JY8QFUQ01C50UA productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7177 JY8QFUQ01C528X productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 7178 JY8QFUQ01AS9PX productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFDNW in-frame + tctggattcaccttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtgataaatactatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatgaacagcctgagaagtgaagacacggctgactattactgtgcgaaagacccatttatagcagcaactggccgcccctggtattttgacaactggggccagggagccctggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7179 JY8QFUQ01BZ5XE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 780 84.09 185/220 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ttccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 7180 JY8QFUQ01CS9RD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCFNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctttaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7181 JY8QFUQ01B5UAN No results 7182 JY8QFUQ01BXDTL No results 7183 JY8QFUQ01A0L0Z productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 838 87.21 191/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-8*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKGGGTFGLRGYGMDVW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcagttcttatggcatgcactgggtccgccaggctccaggcaaggggctgcagtgggtggcattcatatcgtatcatggagatactaaagactatgcagagtccgtgaagggccgactcaccatctccagagacaattccaagaacaaattatatttacaaatgaggagtctgacaagtgaggacacggctgcctattactgtgcaaagggcgggggaacttttggcctaagggggtacggcatggacgtctggggccacgggaccacggtcatcgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctgctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7184 JY8QFUQ01CMMBR productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7185 JY8QFUQ01BV0PE No results 7186 JY8QFUQ01C5YHG productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7187 JY8QFUQ01DNZE4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1005 95.45 210/220 nt 95.0 209/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); ggcctctggattcagcttGcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7188 JY8QFUQ01AUV1R unproductive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] CARQGA**WTLE#DYW out-of-frame + stop codons ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggcatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7189 JY8QFUQ01AV0AZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 467 70.92 139/196 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AV0AZ ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7190 JY8QFUQ01CLRMU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 7191 JY8QFUQ01AF7WD No results 7192 JY8QFUQ01A8SUE No results 7193 JY8QFUQ01CRX6K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 169 82.0 41/50 nt Homsap IGHD4-17*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDRLNGDYTFGAFDLW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaacggtgactacacattcggcgcatttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccaggtgacggtgtcgtggaaactc 7194 JY8QFUQ01BOSQL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7195 JY8QFUQ01AE7KL No results 7196 JY8QFUQ01CNJXO productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7197 JY8QFUQ01CSNHN unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7198 JY8QFUQ01APQA8 productive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7199 JY8QFUQ01CLMWX productive (see comment) Homsap IGHV3-9*01 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); cctctggatTtaacctttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7200 JY8QFUQ01B2XKD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 7201 JY8QFUQ01CWUC3 No results 7202 JY8QFUQ01BAPUZ No results 7203 JY8QFUQ01A22DL No results 7204 JY8QFUQ01AVF5E unproductive Homsap IGHV3-11*01 F 891 90.32 196/217 nt Homsap IGHJ6*01 F 93 64.71 33/51 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CTRRGFMDV# out-of-frame + ctctggattcactttcagtgactactacatgaattgggtccgccaggctccagggaagggcctggagtggctttcatacattactgcaagtggtgccatcatacactatgcagactctgtgaagggccgattcatcatctccagggacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaaggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 7205 JY8QFUQ01DWOBL No results 7206 JY8QFUQ01DOXH7 unknown (see comment) Homsap IGHV3-74*03 F 162 59.83 70/117 nt 8 8 X 8.8.X [1.17.4.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtc 7207 JY8QFUQ01CLHEU productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CNTDLGGSWYTFYSDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 6 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) ctctggatacactgtcataaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 7208 JY8QFUQ01DUDRD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 980 95.35 205/215 nt 94.42 203/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.16.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctggattcacctacagcagcGtatgccatgagctggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7209 JY8QFUQ01BQERB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 8 8.8.8 [1.17.38.11] CAKRYSLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctctggattcacctttaagaactatgccttaaAactgggtccgccaggctccagggaaggggctgaagtgggtctccggaatcagtgctactggtgaaagcacacactacgcagactccgtaattggccggttcaccatctccagagacgattccaagaatacgttatatctgcaaatgaacagcctgagagccgaggacacggccgtatatttctgtgcgaaacgatattctcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 7210 JY8QFUQ01AU3N4 No results 7211 JY8QFUQ01A7ZD8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7212 JY8QFUQ01AKSDK No results 7213 JY8QFUQ01AL0HO productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 853 89.2 190/213 nt 88.73 189/213 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [0.16.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccaggaagggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7214 JY8QFUQ01AQZ7D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [0.17.38.11] CTRDIGGRYSYW in-frame - cggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7215 JY8QFUQ01B38Y1 No results 7216 JY8QFUQ01A627H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttttggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggcaacgtggtcgtcgcatgcctggtccagggcttccttcccccg 7217 JY8QFUQ01CWZ6T productive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 7 8 6 7.8.6 [1.17.38.11] CVKSIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) cctctggattcacatttagcagttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7218 JY8QFUQ01ALE0U No results 7219 JY8QFUQ01DJBL8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - tcctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7220 JY8QFUQ01DF9MN productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 862 89.67 191/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 7 11 8.7.11 [1.17.38.11] CARDRQSWGIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7221 JY8QFUQ01CU7F2 productive Homsap IGHV3-30*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7222 JY8QFUQ01BLLRQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + cctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 7223 JY8QFUQ01B0QFN productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7224 JY8QFUQ01ADN3R productive Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 839 86.88 192/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [1.17.38.11] CAHFGPQEHFDFW in-frame + tctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7225 JY8QFUQ01C83PZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7226 JY8QFUQ01DB51K productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt 97.36 221/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgGagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7227 JY8QFUQ01CD61U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [2.17.38.11] CVREGAATGSFYYW in-frame - acctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7228 JY8QFUQ01CH9Y2 unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7229 JY8QFUQ01DLOWS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7230 JY8QFUQ01BHEVY No results 7231 JY8QFUQ01ALCUA No results 7232 JY8QFUQ01B8NBJ unproductive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVIPGRGNYA#FDVW out-of-frame + stop codons ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgctttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7233 JY8QFUQ01C2A2E productive (see comment) Homsap IGHV3-13*01 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [2.17.38.11] CAREVTRLTVPYYLYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); gtctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccGggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7234 JY8QFUQ01B0Z1K productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7235 JY8QFUQ01BJU8Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactacttcccccgaaccggtgacggtgtgcgtggaactcag 7236 JY8QFUQ01BW8SK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7237 JY8QFUQ01BXPG4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD1-1*01 F 1 7 8 15 7.8.15 [2.17.38.11] CAKDVTFESHFFAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) agcctctggattcaccttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtatctggaaatgagcagtctgagagttgaggacacggccttgtattactgtgcaaaagatgtcacatttgaaagtcacttcttcgctatggacgtctggggccaagggaccacggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7238 JY8QFUQ01BE71O unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 648 77.42 168/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactatttccccgaaccggtgacggtgtcgtggaactcag 7239 JY8QFUQ01AVODA No results 7240 JY8QFUQ01ALKSP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-9*01 F 1 8 8 21 8.8.21 [1.17.38.11] CATARPTNARRYFAWLSQLFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'T' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); cctctggattcaatttcagtaattacaccatgaactgggtccgccagcctccagggaagaggcTtggagtgggtcgcatccattaatgttggcactacttatatatattacggagacgcagtgaagggccgattcaccatctccagagacgacgccaagaactcgttgtttctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgacagcccgccccacaaacgcaagacgatattttgcctggttatcgcaactctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7241 JY8QFUQ01CGG03 No results 7242 JY8QFUQ01CB86C unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7243 JY8QFUQ01BBLQU productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 211 88.68 47/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIRLGDWCFDIW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctggggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7244 JY8QFUQ01CJR5I No results 7245 JY8QFUQ01A3GKV productive Homsap IGHV4-39*02 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + ctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctgatccagggcttcttccc 7246 JY8QFUQ01BEHBE productive (see comment) Homsap IGHV3-9*01 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [2.17.37.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 158 in the user submitted sequence), (cause frameshift) agcctctggattcactttgatggactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactactttcccgaaccggtgacggtgtcgtggaactcag 7247 JY8QFUQ01AZKGW unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 781 84.98 181/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [X.17.38.11] CARDNVTFWDAFDI## out-of-frame - Low V-REGION identity (84,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatttggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcaccctatatttacaaatgaatagcctgagagtcgaggacacggctgtgtattactgcgcgagagataatgtcaccttttgggatgcctttgatatttggggcccgggggacaacggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggnccagggcttcttcccccag 7248 JY8QFUQ01AB5G0 No results 7249 JY8QFUQ01DA6Y3 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctcctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7250 JY8QFUQ01BOPKJ No results 7251 JY8QFUQ01DEYUA productive Homsap IGHV3-13*01 F 903 91.59 196/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [1.17.38.11] CAREVTRLTVPYYLYFDLW in-frame + ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7252 JY8QFUQ01AKAO6 No results 7253 JY8QFUQ01AL1GA unproductive (see comment) Homsap IGHV3-48*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7254 JY8QFUQ01BMK34 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 957 92.38 206/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7255 JY8QFUQ01A7QTA unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 7256 JY8QFUQ01A60BS unknown (see comment) Homsap IGHV3-7*03 F (see comment) 460 67.58 148/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (67,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7257 JY8QFUQ01B0ROB unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 765 83.41 181/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7258 JY8QFUQ01CEI9Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 535 92.06 116/126 nt 91.27 115/126 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 X 19 8.X.19 [1.6.26.11] CANASPRITGTYFYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7259 JY8QFUQ01B9GV0 No results 7260 JY8QFUQ01BZGDR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 7261 JY8QFUQ01BCV2O productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 939 93.46 200/214 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASVVTINDNGDYTWAFDVW in-frame + ctatggtgggtccttcaataattacttctggacctggatccgccagtccccagggaaggggccggagtggattggggaaatcaatcatagtggtagcaccaactacaatccgtccctcaagagtcgagtcaccatctcaatagacacgtccaagatccagttctccctgcagctgagctctgtgaccgccgcggacacggctgtctattactgtgccagtgtagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 7262 JY8QFUQ01A5JF4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7263 JY8QFUQ01CO5KN productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*04 F (see comment) 315 77.06 84/109 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 X X 13 X.X.13 [X.X.36.11] CARGGGGKSIPLDNW in-frame + Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggcttcacgttcagtagttatggcatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7264 JY8QFUQ01CDC70 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.16.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaaggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7265 JY8QFUQ01BC4RR No results 7266 JY8QFUQ01BHL2L No results 7267 JY8QFUQ01DTYCY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7268 JY8QFUQ01ASNTD No results 7269 JY8QFUQ01B3YMQ unknown (see comment) Homsap IGHV3-23*05 F 116 54.14 72/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcacctttagcaactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7270 JY8QFUQ01CNKFF productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + tctggattcaccttcagtatccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7271 JY8QFUQ01ALFQX productive Homsap IGHV4-61*03 F 152 66.25 53/80 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 X X 13 X.X.13 [X.X.26.11] CATVRHLGERIFDFW in-frame - tctctggggccaccatgagtagtttctactggagctggctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7272 JY8QFUQ01BH8BR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 805 86.11 186/216 nt 85.19 184/216 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 7 17 8.7.17 [1.16.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctgggattcagcttaagttcttatggcatgaactggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtattagtagtataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7273 JY8QFUQ01BWDQ9 productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame - cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7274 JY8QFUQ01CLN2W productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7275 JY8QFUQ01BRKIN No results 7276 JY8QFUQ01DRFXI productive (see comment) Homsap IGHV4-61*02 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 114 in the user submitted sequence), (cause frameshift) ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7277 JY8QFUQ01BV6MY No results 7278 JY8QFUQ01AKC4T productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7279 JY8QFUQ01CDXQM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7280 JY8QFUQ01AJ9G4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7281 JY8QFUQ01AQN6R No results 7282 JY8QFUQ01BP92X productive Homsap IGHV3-7*01 F 882 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7283 JY8QFUQ01BGZXV productive (see comment) Homsap IGHV3-7*01 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [0.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); tggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacatAaaagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaAccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggtgccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7284 JY8QFUQ01C847F productive (see comment) Homsap IGHV3-11*01 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7285 JY8QFUQ01CXFYZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7286 JY8QFUQ01BWKDJ unproductive (see comment) Homsap IGHV3-9*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [1.17.38.11] CAK*YGVYLE#YIDHW out-of-frame + stop codons ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattattgtgcaaaatgatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 7287 JY8QFUQ01A0GI6 productive (see comment) Homsap IGHV4-61*02 F 906 90.45 199/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.16.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) tctctggtggccccatcagcagtggtacttactactggacttggatGccggcaggccgccgggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7288 JY8QFUQ01BBJ9Z productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7289 JY8QFUQ01A7PO5 unknown (see comment) Homsap IGHV3-74*03 F 115 54.2 71/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ttctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 7290 JY8QFUQ01A07AL No results 7291 JY8QFUQ01AQOTE No results 7292 JY8QFUQ01CWG6U No results 7293 JY8QFUQ01CFCLX No results 7294 JY8QFUQ01DJGQJ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt 86.7 189/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD3-9*01 F 3 7 8 X 7.8.X [2.16.38.11] CASLNTHAGPGAERSAFDI## out-of-frame - in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) gccctctggattcaccttcagtaacacagaatgaattgggtccgtcagctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgccaaggggtcactctatctgcacatgagctaccttagagccgaggacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgaaaggtctgcttttgatatctgggggccaagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7295 JY8QFUQ01A5XYT productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7296 JY8QFUQ01C5XRQ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 7297 JY8QFUQ01BG1NI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctagtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7298 JY8QFUQ01ALKNG productive Homsap IGHV3-7*01 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [0.17.38.11] CSRHGGYTKLYNQNVYLDYW in-frame - ctggattcacatttagcaacttttggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaaaataaacccagtcggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgaaactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7299 JY8QFUQ01CGEFL No results 7300 JY8QFUQ01CI7BL productive (see comment) Homsap IGHV2-5*01 F 1054 92.28 227/246 nt 91.87 226/246 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 10 7 14 10.7.14 [10.17.38.11] CVHGIMIRGNYNFDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'CG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); cagaccctcacgctgacctgcaccatttctgggttctcactcaacactgatgcagtgggtgtCGggggtggatccgtcagcccccaggaaaggccctggagtggcttgccctcaattattggaataatgataagcgctatagcccatctctgaggagtaggctcaccatcaccaaggacacttccaaaaaccaagtagtcctcacaatgaccaacatggaccctgtggacacagccacgtattattgtgtacacggtattatgattcggggaaattacaactttgactattggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7301 JY8QFUQ01AE5NB No results 7302 JY8QFUQ01A38QG No results 7303 JY8QFUQ01AXWK7 No results 7304 JY8QFUQ01CMKMT productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7305 JY8QFUQ01BEOIK productive Homsap IGHV3-11*01 F (see comment) 740 83.49 177/212 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 7 8 15 7.8.15 [X.17.38.11] CARVRCSGNTCGAFDLW in-frame - Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gattcagcttaagtgactactacatgacctgggtccgccaggccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaccgtctccagggacaacgtccaaaactcactgtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7306 JY8QFUQ01CYKKW No results 7307 JY8QFUQ01C8HIY unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 778 84.72 183/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [2.17.38.11] CARERGSGPP#GMDVW out-of-frame - Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ggttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7308 JY8QFUQ01DDY85 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7309 JY8QFUQ01CABSD unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 867 87.44 195/223 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CTADVPSPLAQNDF# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7310 JY8QFUQ01DHRCK No results 7311 JY8QFUQ01CYA9E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1075 100.0 216/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7312 JY8QFUQ01CUN1J No results 7313 JY8QFUQ01CY6MC productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame + ctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 7314 JY8QFUQ01A6JDD unknown (see comment) Homsap IGHV3-47*01 P, or Homsap IGHV3-7*01 F or Homsap IGHV3-7*03 F 148 57.6 72/125 nt 8 6 X 8.6.X [1.17.9.X] null + No rearrangement found cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctgcagcacccagccagatggggacgtggtcatcgcctgcctggtccagggcttcttccccca 7315 JY8QFUQ01CIOPG productive (see comment) Homsap IGHV4-39*02 F 862 87.84 195/222 nt 87.39 194/222 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [2.17.38.11] CARQMGYSGSGLSVWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gtctctggaggctccatcaacactaatcgttactactgggtctggtttcgccagAcccccggggaaggggctggagtggattgggactatttattatactgggatcaccaactacaatccattcttcaagagtcgagtcaccatgtccgtagacacgtccagccaccacttctccctgaggttgagctctgtgaccgccgtagacacggctgtctactactgtgcgagacaaatgggatactctggttcggggctcagtgtgtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7316 JY8QFUQ01BNQF3 productive Homsap IGHV3-30*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame + cctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7317 JY8QFUQ01B5FXA No results 7318 JY8QFUQ01CIV81 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7319 JY8QFUQ01A1MW1 unknown (see comment) Homsap IGHV3-7*01 F 981 94.47 205/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 7320 JY8QFUQ01A45PJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7321 JY8QFUQ01BHUNQ No results 7322 JY8QFUQ01DBFW5 No results 7323 JY8QFUQ01A2XWB productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7324 JY8QFUQ01BJCGQ productive (see comment) Homsap IGHV3-30*01 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDFDTDDVGTYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 214 in the user submitted sequence), (cause frameshift) tctctggattcatcttcgatagttatgctctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttgtttcatatgatggaaaatataagcaatatgcagattctgtggagggccgattcaccatctccagagacaactccaagaacacaggatatctgcaaatgaacagcctgacatctgacgatacggctgtgtattttgtgcgagagacttcgatactgacgacgtgggcacctactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7325 JY8QFUQ01CYR3J productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgca 7326 JY8QFUQ01A27H2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccagttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7327 JY8QFUQ01CQQVZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7328 JY8QFUQ01BS83C productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7329 JY8QFUQ01AKSZ0 No results 7330 JY8QFUQ01C7RKZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 7331 JY8QFUQ01BDK0T productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 7332 JY8QFUQ01BNJGF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7333 JY8QFUQ01ASTYN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.16.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactgagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7334 JY8QFUQ01CG6JV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 7335 JY8QFUQ01CPCC5 No results 7336 JY8QFUQ01CB4MT productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7337 JY8QFUQ01BQT9J productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctggattcagcttcagagactatggcatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatacattggtaggattattagtgacatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7338 JY8QFUQ01ACO6B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagcagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7339 JY8QFUQ01B3G3T productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 11 8.8.11 [1.17.37.11] CNLHPYGDSSDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) ctctggactcaccttcagtcgcctctggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatagatagtgatgggaataacataatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaaacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtaaccttcatccctacggtgactcctccgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7340 JY8QFUQ01C9I3O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7341 JY8QFUQ01AO5SQ unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 138 56.06 74/132 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons tctggattcaccttcagtgactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7342 JY8QFUQ01A47U3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1045 97.72 214/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [2.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - gcgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7343 JY8QFUQ01BR1YM productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CATSPSVGSTTVGYW in-frame + ctctggattcacctttagaaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgacagatggaggtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgccacatcccctagcgtgggatctacgacggtgggctactggggccggggaaccctggtaaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7344 JY8QFUQ01CIQBS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttctccca 7345 JY8QFUQ01B5GNU productive (see comment) Homsap IGHV3-48*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); cctctggatTtcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7346 JY8QFUQ01BMVQV productive (see comment) Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.16.38.11] CARGGSGGAYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 111 to 122 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaaggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7347 JY8QFUQ01AZ07T productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 7348 JY8QFUQ01APEOL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7349 JY8QFUQ01CHJQ8 No results 7350 JY8QFUQ01BW6QX productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7351 JY8QFUQ01DABFP productive (see comment) Homsap IGHV4-39*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [2.16.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtgactccatttccagtactagttattactggggctgggtccgccagccccagggaaggggctggagtggaTttgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7352 JY8QFUQ01DR0WN productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 7353 JY8QFUQ01AZ2P8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7354 JY8QFUQ01CWGWW unknown (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F 103 57.3 51/89 nt 8 4 X 8.4.X [0.17.X.X] null - No rearrangement found ctggatttacctttagcagttatgccatgaactgggtccgccagatggaaacgtggtcatcgcctgcctggtccagggcttcttcccca 7355 JY8QFUQ01A5WBI productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7356 JY8QFUQ01BIL7K No results 7357 JY8QFUQ01A8CYP No results 7358 JY8QFUQ01A8MTS No results 7359 JY8QFUQ01AXEG5 No results 7360 JY8QFUQ01A5OJ5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7361 JY8QFUQ01CAVYT unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctctcagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7362 JY8QFUQ01BEP9A productive Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame - ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccagaaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7363 JY8QFUQ01A3QEB productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame + ctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7364 JY8QFUQ01AFME4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 469 82.48 113/137 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (82,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 7365 JY8QFUQ01BGBMV unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7366 JY8QFUQ01A7HQ8 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaact 7367 JY8QFUQ01BTRU2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggcgtcgtggaactc 7368 JY8QFUQ01C7540 productive Homsap IGHV3-30*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7369 JY8QFUQ01BJNO1 No results 7370 JY8QFUQ01AD1LR unproductive (see comment) Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7371 JY8QFUQ01ATFLQ No results 7372 JY8QFUQ01A5ZNA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 849 90.73 186/205 nt 89.76 184/205 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift) ctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7373 JY8QFUQ01BS9AI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7374 JY8QFUQ01DM0N2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 800 86.05 185/215 nt 85.12 183/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDTGSSKFARYDGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) tctggattGcagcctcagtacctctggcttgaactgggtccgcaggccccagggaagggactggagtggatctcattcatcaatagtgatggtgattacatctactacgcggagtcggtgaggggccgattcaccatctccagagacaacgccgagaagtcactgtacctgcaactgaacaacctgagagtcgaggacacggctgtgtacttctgtgcgagagataccggctcgtccaagttcgctaggtacgacggtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7375 JY8QFUQ01A8Y0H productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame - ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7376 JY8QFUQ01CJDL1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame + ctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7377 JY8QFUQ01BZ1XN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + cctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 7378 JY8QFUQ01B3WVJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + tctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7379 JY8QFUQ01BFAIH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7380 JY8QFUQ01CS7MX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7381 JY8QFUQ01ALST3 No results 7382 JY8QFUQ01DLI3D productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.16.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) tctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaagggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7383 JY8QFUQ01A4ORW productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7384 JY8QFUQ01C5TJ1 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDNARSYYSGVPDFW in-frame - gcgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7385 JY8QFUQ01BL0SP No results 7386 JY8QFUQ01DFWE1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 482 68.81 150/218 nt 68.35 149/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (68,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaaggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7387 JY8QFUQ01A5VNA productive (see comment) Homsap IGHV4-59*03 F 931 92.59 200/216 nt 91.2 197/216 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GA' (2 nucleotides at position 65 to 66 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 95 to 100 in the user submitted sequence), (do not cause frameshift); gtctctggtgtctccatcagtagtttctactggagttggatgaggcagGCcccccagggaggggGAcctggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7388 JY8QFUQ01C90SW productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcgggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7389 JY8QFUQ01DSC06 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg 7390 JY8QFUQ01AWB4I productive (see comment) Homsap IGHV4-4*07 F 844 88.32 189/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.37.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtcCaaaaccagtgggaccccccactacaacccttccctnaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccattttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7391 JY8QFUQ01BNKPL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 7392 JY8QFUQ01C6ROW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7393 JY8QFUQ01DIP2F unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 823 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.16.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccCttcaggaactattggatgcactgggtccgccaagctccagggaagggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacacgctgtatctgcaaatgaacagtctgagagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7394 JY8QFUQ01AVC46 productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcag 7395 JY8QFUQ01B7ZEV No results 7396 JY8QFUQ01BYSCW No results 7397 JY8QFUQ01CEODQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctatgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7398 JY8QFUQ01BL30A productive (see comment) Homsap IGHV4-61*01 F (see comment) 781 83.78 186/222 nt 83.33 185/222 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [2.17.38.11] CARDGNRGYYSFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); gtgtctggtggctccgtcagcagtggaaattcctactggacctTggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7399 JY8QFUQ01A1TPB productive Homsap IGHV4-39*03 F 924 91.32 200/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7400 JY8QFUQ01DL8E9 No results 7401 JY8QFUQ01ARLMX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKNLRLGHSYFYNALDVW in-frame + tctctggtggcctcatcagtaattactattggacctggatccggcagcccccaggaaagggactggagtggattgggaacatctattacagtgggagcgccacctacaacccctccctcaagagtcgagtcaccatatcaatagactcgtccaagaaccagttctccctgaggctgaccgctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaacttacgattgggtcacagttacttctacaacgctttggacgtatggggccaagggaccacggtcaccgtcgcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7402 JY8QFUQ01C8III productive Homsap IGHV3-30*01 F 995 95.41 208/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD1-1*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAREPGRGYTPAMNWYFDLW in-frame + cctctggattcaccttcagtagccatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgggggttatatcatctgatggaagtaatgaatactatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactgtatctgcagatgaacagcccgagagctgaggacacggctgtgtattactgtgcgagagagcctgggaggggttatacacctgcaatgaactggtacttcgatctctggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7403 JY8QFUQ01AZ4D4 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcca 7404 JY8QFUQ01AYJT7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactcag 7405 JY8QFUQ01CBSRV productive (see comment) Homsap IGHV3-64*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); cctctggattcaAttttcagtacttatcctatgcactgggtccgccaCggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7406 JY8QFUQ01BIOGX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 848 87.33 193/221 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame - cagcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaatgggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7407 JY8QFUQ01BO9AE No results 7408 JY8QFUQ01A7RV9 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) cctctggattcaccttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7409 JY8QFUQ01AW0QG productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + ctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7410 JY8QFUQ01AIXDP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7411 JY8QFUQ01DLITS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7412 JY8QFUQ01BFSZY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7413 JY8QFUQ01C28FC unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1038 96.41 215/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 X 8.10.X [1.17.38.11] CTRDNPPLRSLEWL#FDSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttacctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 7414 JY8QFUQ01AC8SF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 91.71 199/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 115 to 116 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagttactcctggatgcactTgggtccgccaagttccaggaaaggggccggtgtgggtGctcacgaAattcaaagtgatgggagtaccccaagttacgcACggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7415 JY8QFUQ01BST27 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaact 7416 JY8QFUQ01C3ZS5 No results 7417 JY8QFUQ01BMI4Y unknown (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found ctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaaggggtacaacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 7418 JY8QFUQ01CWGS6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtccatcgcctgccctggtccagggcttcttcccc 7419 JY8QFUQ01BTNVR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 7 8 11 7.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) ctctggatcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7420 JY8QFUQ01AONIM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7421 JY8QFUQ01ACRCA No results 7422 JY8QFUQ01CF15N No results 7423 JY8QFUQ01CXAVM No results 7424 JY8QFUQ01B0TRD productive Homsap IGHV3-7*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAKGGGNGDLDYW in-frame - tggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7425 JY8QFUQ01DXGGW No results 7426 JY8QFUQ01C0Y8B unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagcccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 7427 JY8QFUQ01CKUIL No results 7428 JY8QFUQ01AG17N productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ccggattcagtttcagtacttaGtaacatgaattgggtccgccaggctccagggaaTggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcagccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7429 JY8QFUQ01C79VR No results 7430 JY8QFUQ01DIG69 No results 7431 JY8QFUQ01A6LUO unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtctcaaccattggtactagaggtagatccatatactacgcggactcagtgaagggccgattcaccacctccagagacaacgccaagaaatcactttatctggatatgcacagcctgagagccgaggacacggctatctattactgtgcgagagatggcagtgcacactcgtcgatctatcattactattacggcatggacgtctggggccaaggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 7432 JY8QFUQ01DBDPM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - cagcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7433 JY8QFUQ01CGYN6 productive Homsap IGHV3-72*01 F 930 91.03 203/223 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-3*01 F 2 8 10 14 8.10.14 [1.17.38.11] CLRGFSSHYRGGMDVW in-frame + ctctggactcacgttcagtgaccactacatggactgggtccgccagactccagggaggggactggagtgggttggccgtattagagacaaagctcgcaggtacaccacagaatacgccgcgtctgtgaaaggcagattcaccattttaggagatgatttaaagaattcactgtatctacaaatgaacaacctgagaaccgacgactcggccgtgtattactgtctcagaggattttcgagccattatcggggcggtatggacgtctggggccaagggaccacggtcaccgtgtccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7434 JY8QFUQ01DWWST unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CAKEGPTLLTRPPSQL# out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgccccccatctcaactggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7435 JY8QFUQ01AOY3W productive (see comment) Homsap IGHV3-48*03 F 858 89.25 191/214 nt 87.85 188/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgcatgaactggtccgcctgtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7436 JY8QFUQ01C6CR5 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 92 52.31 68/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 7437 JY8QFUQ01ACS2Y productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7438 JY8QFUQ01DBA0T productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AGCCCCA' (7 nucleotides at position 81 to 87 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcaAGCCCCAaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7439 JY8QFUQ01CJLXK productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + gtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7440 JY8QFUQ01BSOXE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 7441 JY8QFUQ01CKN05 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame + tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7442 JY8QFUQ01AVUA3 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 264 72.38 76/105 nt 8 7 X 8.7.X [1.17.1.X] null - No rearrangement found Low V-REGION identity (72,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttccccca 7443 JY8QFUQ01AAWVK productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaacccctggtcaccgtctcctcagcatcccccgaccagcccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7444 JY8QFUQ01AOPX0 No results 7445 JY8QFUQ01AH2Q8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 250 100.0 50/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame + ctctggattcacctttagcagctatgccatgggctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtgggagtggtcggagcacatactacgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccatatattattgtgtgaaaaggttggaaggagtggctgatgatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7446 JY8QFUQ01ADH3O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7447 JY8QFUQ01BPLSQ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7448 JY8QFUQ01BR0ES productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 909 91.24 198/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcatcttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7449 JY8QFUQ01ALI8J productive (see comment) Homsap IGHV3-64*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 7 8 10 7.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcatttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7450 JY8QFUQ01BX8NY productive Homsap IGHV3-66*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [2.17.38.11] CARQTAPFGYFEDW in-frame - acctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7451 JY8QFUQ01DML2W unproductive Homsap IGHV1-8*01 F 993 96.26 206/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CARDPNSGG#YW out-of-frame - tggatacaccttcagcaattatgacatcaactgggtgcgacaggccactggacaagggcttgagtggatgggacggatgaaccctgacagtggaaacacagactatgcacagaggttccagggcagagtcaccatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgagagatccgaattcgggggggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgttgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7452 JY8QFUQ01DN37C productive (see comment) Homsap IGHV3-48*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARDMIIFGGALDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7453 JY8QFUQ01CJ7C5 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 92.83 207/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); ctctgcagcctctggattcattgtcaatagcaactacatgGagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7454 JY8QFUQ01BBIUK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7455 JY8QFUQ01C2RJ9 No results 7456 JY8QFUQ01A7YQM No results 7457 JY8QFUQ01BR9AM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 448 70.1 136/194 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BR9AM ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7458 JY8QFUQ01DHYKY productive Homsap IGHV2-5*02 F 954 88.11 215/244 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 10 7 11 10.7.11 [9.17.38.11] CVRMDVDTAVDFW in-frame - gaccctcacactgacctgcacctgctctggattctcactcaccgataacggagtgggtgtgggctggatccgtcagcccccaggacaggccctgcagtggcttgcactcgtttattgggatgatgatatgcgccacaactcatctctgaggaacagagtcatcatcgccagggacacctccaagaaccaggtggtcctaacattggccaacatgggccttgtggacacagccacatatttctgtgtgcgcatggacgtggatacggctgtagatttctggggccagggaatcctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7459 JY8QFUQ01DBRNA unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7460 JY8QFUQ01CGU5O productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 21 8.8.21 [0.16.38.11] CARGWLTAADTGVASGHDWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tggatacaccttcaccagctactatatgcactggatacgacaggcccctggacaaggcttgagtggatgggaataatcaaccctagtggtggtaccacaaggtacgcacagaagttccagggcagagtcttcatgaccagagacacgtccacgagcacagtccacatggaggtgaacggcgtaagatctgacgacacggccgtgtattactgtgcccgagggtggctgacagcagctgataccggggtggcgtcagggcacgattggttcgactcctggggccagggaaccctggtaaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7461 JY8QFUQ01C4E92 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*04 F (see comment) 314 60.47 130/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (60,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctatggtgggtcactcagttcttatttctggagctggatccgccagtccccagagaaaggactggagtggattggggaaatcaatcagagtggaaccaccaactacaacccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7462 JY8QFUQ01CNGTA productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7463 JY8QFUQ01BFMTU No results 7464 JY8QFUQ01CHR3O productive Homsap IGHV3-11*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDRGKSGSYGLDHW in-frame + ctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatcgggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7465 JY8QFUQ01CBVG3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARYGSGSQKYLDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccctcaataattactactggagttgggtccggcagcCccccagggaagggactggagtggattgggtggatctattacaatgggatcaccgcctacaacccctccctcaagagtcgactcaccatatcagtggacacgtccacgaaccagttctccctgaggctgttctctgtgaccgctgcggacacggccgtgtattattgtgcgagatatggtagtggttcccaaaaatacttggactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7466 JY8QFUQ01DCPQS unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGS## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccaTgggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7467 JY8QFUQ01CAM1Y unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ1*01 F, or Homsap IGHJ5*02 F (see comment) 110 69.39 34/49 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDY# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcacgtttggttcgtattggatgagttgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactgggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7468 JY8QFUQ01A9X74 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 7469 JY8QFUQ01BCZ3W productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7470 JY8QFUQ01B5689 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 7471 JY8QFUQ01B5XLS productive (see comment) Homsap IGHV3-30*07 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattctccttcagaagttaCtcttttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7472 JY8QFUQ01C3D8T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccaatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttctccgaaccggtgacggtgtgcgtggaactcag 7473 JY8QFUQ01A9WLN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7474 JY8QFUQ01DBVGM unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGVVTA#LDYW out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 7475 JY8QFUQ01BOT3U unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7476 JY8QFUQ01CRR36 No results 7477 JY8QFUQ01ANP89 productive Homsap IGHV3-48*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARAGGNCYDAGECWFDPW in-frame + ctctgggttcgccctcagttcctatagcatgaactggctccgccaggctccagggaagggactggagtggatttcatacattagtagtactagtgttgtcatacgctatgcagactctgtacaaggccgattcaccatctccagagacaatgccaagaactcactgtttctgcaaatgaatagtctgagagacgaggacacggctgtttattactgtgcgagagccggtggtaactgctatgacgccggtgaatgctggttcgacccctggggccagggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7478 JY8QFUQ01A1L2W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CAKDRDPGYCLSNSCVDGLAFDSW in-frame + ctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggtggtaacacatacttcgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtttctacagctgaacagcctgagagccgccgacacggccgtatattactgtgcgaaggatcgtgacccgggatattgtcttagtaatagctgtgttgacggcctagcctttgactcctggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 7479 JY8QFUQ01CLY2T unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7480 JY8QFUQ01CHZU0 unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFLDY## out-of-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7481 JY8QFUQ01A2Y02 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 821 85.97 190/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatgagttttccctgacactgacctctatgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 7482 JY8QFUQ01CLNEV No results 7483 JY8QFUQ01DNPTN No results 7484 JY8QFUQ01DOWDA unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7485 JY8QFUQ01CZONR productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7486 JY8QFUQ01BS3N8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 514 92.44 110/119 nt 8 8 X 8.8.X [1.17.5.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca 7487 JY8QFUQ01CITVF No results 7488 JY8QFUQ01B3CE8 No results 7489 JY8QFUQ01C1ITB No results 7490 JY8QFUQ01BG0J6 No results 7491 JY8QFUQ01DOUX8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgTtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7492 JY8QFUQ01A47K4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7493 JY8QFUQ01AVL05 No results 7494 JY8QFUQ01DOOGE productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggctcctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7495 JY8QFUQ01BLCWW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame - ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7496 JY8QFUQ01C9VGW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFDNW in-frame - ctctggattcaccttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtgataaatactatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatgaacagcctgagaagtgaagacacggctgactattactgtgcgaaagacccatttatagcagcaactggccgcccctggtattttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7497 JY8QFUQ01ASBGD productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7498 JY8QFUQ01BYXZW unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 778 84.72 183/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [2.17.38.11] CARERGSGPP#GMDVW out-of-frame - Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ggttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7499 JY8QFUQ01B7Q1C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7500 JY8QFUQ01C1P2F No results 7501 JY8QFUQ01DNGN1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7502 JY8QFUQ01BRQ4Z No results 7503 JY8QFUQ01CX238 No results 7504 JY8QFUQ01BW1QC productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7505 JY8QFUQ01AN6ZD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 96.63 201/208 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQIDYGDFSRHGLDVW in-frame + caactttaccggctactggatcggctgggtgcgccagcggcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccatccttccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaaatagactacggtgacttctctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7506 JY8QFUQ01C9B7V unproductive Homsap IGHV1-69*02 F, or Homsap IGHV1-69*08 F or Homsap IGHV1-69*11 F (see comment) 610 76.06 162/213 nt 75.59 161/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [0.16.38.11] CAKAGFVLATP#DLW out-of-frame - Low V-REGION identity (76,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) cggaggcaacctaaagacctataccataagttgggtgcgacaggccctggacaggggcttgagtggctgggaaggatcaatcctaagattgggagcaacaattatatacagagattgcaggggagagtcacatttactgcggacgagtcgtcgaacacagcctacttgaagctgagtcgcctaaaacctgacgacacgggcgtctatttctgcgcgaaggcgggcttcgttttggcgaccccccggacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7507 JY8QFUQ01AB5D4 productive Homsap IGHV3-7*01 F (see comment) 664 78.97 169/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccgagnggtggtgccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7508 JY8QFUQ01DQZ7W productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 773 83.04 186/224 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7509 JY8QFUQ01BGQG5 productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7510 JY8QFUQ01DORSO No results 7511 JY8QFUQ01CWUJB No results 7512 JY8QFUQ01A481H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7513 JY8QFUQ01B9YF9 unproductive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [2.17.38.11] CASSVFSPRR#FDYW out-of-frame + stop codons tttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtccccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7514 JY8QFUQ01C2H7F productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1071 99.54 216/217 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame + ttctggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7515 JY8QFUQ01BLZDF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7516 JY8QFUQ01AU0CS productive (see comment) Homsap IGHV3-48*03 F 796 85.65 185/216 nt 84.72 183/216 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 7 8 14 7.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggattcgccttcaaagttttaacatgaattgggtccgccaggcttcagggaaggggcCgggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7517 JY8QFUQ01B5RKV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame + ctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7518 JY8QFUQ01ASDV1 No results 7519 JY8QFUQ01ALVRH productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7520 JY8QFUQ01BU0SA unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKVRGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaggttcggggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7521 JY8QFUQ01B56OG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7522 JY8QFUQ01DVYMJ unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found stop codons cctctgcagcctcttgattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7523 JY8QFUQ01CS3F4 No results 7524 JY8QFUQ01B33D2 No results 7525 JY8QFUQ01DU681 No results 7526 JY8QFUQ01CLTV6 No results 7527 JY8QFUQ01CTUYQ No results 7528 JY8QFUQ01CPD1V productive Homsap IGHV3-30*07 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7529 JY8QFUQ01DPQ1L No results 7530 JY8QFUQ01BNHIS No results 7531 JY8QFUQ01BXKWZ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 14 8.7.14 [1.17.38.11] CAREKVRGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7532 JY8QFUQ01AU9HY unproductive (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 873 89.4 194/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcatcttcagtgactatggcatgcactgggtccgccagactccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactgggggccaggggaacgctggtcaccgtctcctagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaactggtcgtcgcatgcctggtccagggcttcttccccca 7533 JY8QFUQ01C45R9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt 91.2 197/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 7 8 16 7.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) ctctggatcacctttagcagccaTgcccatgtactgggtccgccaagctccagggaaAGggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7534 JY8QFUQ01DQPTM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagccctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7535 JY8QFUQ01C6FHX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1018 96.35 211/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 10 8.8.10 [2.17.38.11] CTREGFDELGYW in-frame - gcctctggattcacctttagcacctatgccatgagctgggtccgtcaggctccagggaaggggctggagtgggtctcagcgattactggtactggtggtaatacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtacgagagaggggttcgatgaattggggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7536 JY8QFUQ01AXBO8 No results 7537 JY8QFUQ01AOX94 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 7538 JY8QFUQ01C1MKL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 764 84.19 181/215 nt 83.26 179/215 nt 7 8 X 7.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggtttggcgtgaactgggtccgccaggctccagggaagggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagaacagcgccttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7539 JY8QFUQ01BL26X productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc 7540 JY8QFUQ01CGCSZ unproductive Homsap IGHV1-18*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [0.17.38.11] CARENLLYFGNSFRLQA#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacatctttaccacctatggtatcagttgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcaacacttacaatggtaacacgaactatggacagaggatccagggcagagtcaccatgaccacagacacatccacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccgtatattattgtgcgagagaaaacctactatacttcgggaattcattccggcttcaggcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 7541 JY8QFUQ01AK8SO productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 7542 JY8QFUQ01A1RK6 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-71*03 P or Homsap IGHV3-72*01 F 283 88.73 63/71 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtggg 7543 JY8QFUQ01BN55O No results 7544 JY8QFUQ01A6UKY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7545 JY8QFUQ01DMPH4 No results 7546 JY8QFUQ01ACCB6 productive (see comment) Homsap IGHV3-11*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggaatggatctcatatatcagtacaagtggtaataTgggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7547 JY8QFUQ01CSWKZ productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7548 JY8QFUQ01C4OV3 No results 7549 JY8QFUQ01BLY5K unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 615 76.64 164/214 nt 75.7 162/214 nt Homsap IGHJ2*01 F, or Homsap IGHJ4*01 F or Homsap IGHJ4*02 F or Homsap IGHJ5*01 F or Homsap IGHJ5*02 F (see comment) 17 71.43 5/7 nt 7 8 X 7.8.X [1.16.38.0] null + stop codons no junction found Low V-REGION identity (76,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*02 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides). The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca 7550 JY8QFUQ01A0224 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7551 JY8QFUQ01DM6TL productive Homsap IGHV3-7*01 F 873 89.4 194/217 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARATNADVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7552 JY8QFUQ01AUKP1 No results 7553 JY8QFUQ01BA28B productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7554 JY8QFUQ01AKGZ2 No results 7555 JY8QFUQ01C69SV No results 7556 JY8QFUQ01BWH5D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7557 JY8QFUQ01CDG42 productive (see comment) Homsap IGHV3-7*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtcccaggggcttcttccccca 7558 JY8QFUQ01CD6VQ No results 7559 JY8QFUQ01CDIA1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7560 JY8QFUQ01BLA0C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7561 JY8QFUQ01CW65U productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcgatattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7562 JY8QFUQ01C0B83 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccc 7563 JY8QFUQ01DJY9E productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7564 JY8QFUQ01BU7PN productive (see comment) Homsap IGHV4-59*03 F 786 85.51 183/214 nt 84.58 181/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.37.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) tctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccCaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7565 JY8QFUQ01B8WDA No results 7566 JY8QFUQ01B634P No results 7567 JY8QFUQ01BXK4Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7568 JY8QFUQ01CIX1S unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggc 7569 JY8QFUQ01DHF28 No results 7570 JY8QFUQ01BC3YW No results 7571 JY8QFUQ01CUCWJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7572 JY8QFUQ01AP5QK productive Homsap IGHV3-48*03 F 868 89.35 193/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + tctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7573 JY8QFUQ01CMIR9 No results 7574 JY8QFUQ01BZL4J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7575 JY8QFUQ01AKB8K No results 7576 JY8QFUQ01BQTTN No results 7577 JY8QFUQ01AGSPU productive (see comment) Homsap IGHV3-9*02 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.37.11] CGKDMRPGGMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 87 of V-REGION: 2 nucleotides (from position 166 in the user submitted sequence), (cause frameshift) ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7578 JY8QFUQ01C6SR8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 645 85.63 149/174 nt 85.06 148/174 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggGggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgc 7579 JY8QFUQ01A0KG1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame + ctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 7580 JY8QFUQ01BZ0C2 No results 7581 JY8QFUQ01C4SJ4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 8 10 8.8.10 [2.17.38.11] CARGDGVKDDYW in-frame - gggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7582 JY8QFUQ01COQYI No results 7583 JY8QFUQ01BC153 productive (see comment) Homsap IGHV3-7*01 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) tctctggattcaccttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7584 JY8QFUQ01A5RRI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7585 JY8QFUQ01A8SED productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 7586 JY8QFUQ01DJWO6 No results 7587 JY8QFUQ01C0OCC No results 7588 JY8QFUQ01C7LOZ unproductive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDI* in-frame - stop codons Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctagggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7589 JY8QFUQ01APVEB unknown (see comment) Homsap IGHV4-4*07 F 799 86.38 184/213 nt 85.45 182/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 6 X 8.6.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 36 of V-REGION: 'TGATGA' (6 nucleotides at position 22 to 27 in the user submitted sequence), (do not cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) gtctggtggctccatcagcagTGATGAttactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaagtggcgacacagtgtacaacccctccctcggggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgagggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7590 JY8QFUQ01AG9TR productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - gcctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7591 JY8QFUQ01BBU5J productive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + tctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 7592 JY8QFUQ01DOFJ6 productive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7593 JY8QFUQ01CV2CC productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 7594 JY8QFUQ01AQ72Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7595 JY8QFUQ01CD2YV No results 7596 JY8QFUQ01CYZO8 productive Homsap IGHV3-9*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKGGNLGGAVAARYFDYW in-frame + ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagcataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcaaaagggggtaacctgggtggggcagtggctgcccggtactttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc 7597 JY8QFUQ01C2F28 No results 7598 JY8QFUQ01C11GI No results 7599 JY8QFUQ01AEY2H No results 7600 JY8QFUQ01BLBFT No results 7601 JY8QFUQ01AN4UP productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'CG' (2 nucleotides at position 194 to 195 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccCGggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7602 JY8QFUQ01C3XP4 productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); gcctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggGactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7603 JY8QFUQ01AU26V unproductive (see comment) Homsap IGHV3-48*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDMIIFGGSP*QL# out-of-frame + stop codons cctctggattcaccttcagcagctttagtatgagctggatccgccaggctccagggaaggggctggagtggattgcatacattactaatagaggcactaccacagactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggcagcccttgacaactggggccagggtaaccctggtcaccgtctccgtctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 7604 JY8QFUQ01AK0IG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7605 JY8QFUQ01BNRVO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - gcctctggattcagcttcaatagttactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7606 JY8QFUQ01C5TD6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttccccc 7607 JY8QFUQ01DBR15 productive (see comment) Homsap IGHV3-74*03 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacGtttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7608 JY8QFUQ01CF6E2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + tctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7609 JY8QFUQ01BSJRI unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKGVVTA#LDYW out-of-frame + ctccggtggctccatcaccagttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatagtgggagcactacctacaactcctccctcaagagtcgagtcaccatatcaggagaagggtccacgcgccagttctccctgaggctgagctctgtgaccgttgcggacacggccgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7610 JY8QFUQ01DSM83 unknown (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7611 JY8QFUQ01BSL3T No results 7612 JY8QFUQ01CNMLX productive Homsap IGHV4-4*07 F 903 91.59 196/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 3 8 7 11 8.7.11 [1.17.38.11] CAARNGNVAFNLW in-frame + ctctggcggctccatctatagttactactggagctgggtccggcagcccgccgggaagggactggagtggattgggcgtatctattccaatggggacaccaactacaacccctccctcaagagtcgggtcaccatgtcagtggacgtgtccaacaatgagttctccctgaacttgaggtctgtgaccgccgcggacacggccgtgtattactgtgcggcgcgaaatggaaatgtggcttttaatctgtggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7613 JY8QFUQ01A7PVL unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 130 55.22 74/134 nt 10 9 X 10.9.X [1.17.7.X] null + No rearrangement found stop codons tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 7614 JY8QFUQ01DUVHH No results 7615 JY8QFUQ01A8ILG No results 7616 JY8QFUQ01DPFSK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 944 93.49 201/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARGPRSRGYGMDVW in-frame + ctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcagccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 7617 JY8QFUQ01DDHVF No results 7618 JY8QFUQ01C7PE2 No results 7619 JY8QFUQ01A3D8L unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccaggggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7620 JY8QFUQ01CKR8P productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDGGSYNRMDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) gtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcAaaggggctggagtggatggcaattatatggtatgatgggaaaataaatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaattccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7621 JY8QFUQ01BTDAB unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 7622 JY8QFUQ01DGTB2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 7623 JY8QFUQ01BAUZH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.37.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 57 to 59 in the user submitted sequence), (do not cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggGAAagggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7624 JY8QFUQ01C9O65 No results 7625 JY8QFUQ01DQZTR productive Homsap IGHV3-33*04 F (see comment) 697 80.56 174/216 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7626 JY8QFUQ01DI5X6 productive (see comment) Homsap IGHV3-11*01 F 992 96.7 205/212 nt 95.75 203/212 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 12 8.8.12 [0.17.37.11] CAVDCTSISCNGDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 102 of V-REGION: 2 nucleotides (from position 208 in the user submitted sequence), (cause frameshift) ctgggttcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgaggccgaggacacggccgtgtaactgtgcggtagattgtactagtatcagctgcaacggagactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7627 JY8QFUQ01DSQGA unproductive Homsap IGHV3-30*07 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDTITMGGDVAPLFDY## out-of-frame + ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactgggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 7628 JY8QFUQ01B5QED No results 7629 JY8QFUQ01DCVW2 No results 7630 JY8QFUQ01ASVJP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggaTgggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctagtccagggcttcttccccca 7631 JY8QFUQ01C85DX No results 7632 JY8QFUQ01DAKAC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca 7633 JY8QFUQ01CWK5E No results 7634 JY8QFUQ01DFTG1 No results 7635 JY8QFUQ01BR38G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7636 JY8QFUQ01BZCAL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7637 JY8QFUQ01BPN7S No results 7638 JY8QFUQ01BXMV3 productive Homsap IGHV3-7*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + tctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7639 JY8QFUQ01AREM5 productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7640 JY8QFUQ01BRBZO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7641 JY8QFUQ01AHPMF No results 7642 JY8QFUQ01COP7W No results 7643 JY8QFUQ01CIH47 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7644 JY8QFUQ01C98TL No results 7645 JY8QFUQ01CHHZ3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 942 92.27 203/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame - ctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 7646 JY8QFUQ01AXNM5 No results 7647 JY8QFUQ01A110D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVAVGMSGWFDPW in-frame - gcctctggattcaccttcagtaactactggatgtattgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggcagtagcacaagctacggggactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttgggatgtcaggctggttcgacccttggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7648 JY8QFUQ01CHORL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7649 JY8QFUQ01B98D4 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7650 JY8QFUQ01CX1TG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7651 JY8QFUQ01A5WXC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [1.17.37.11] CAREVTRLTVPYYLYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) ctctggattcccctttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccgggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7652 JY8QFUQ01BHOD4 No results 7653 JY8QFUQ01B1FVC productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.16.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) ctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaagggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaaaggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7654 JY8QFUQ01CF3ZO No results 7655 JY8QFUQ01CF06T productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 7656 JY8QFUQ01BCV43 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7657 JY8QFUQ01DWUWS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPLYNWN#YFYYYGMDVW out-of-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 7658 JY8QFUQ01A7OHA unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRVGAAILRFLEWLSD#NWFDPW out-of-frame + stop codons tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgctagtactacttccatacactatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggccgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttccc 7659 JY8QFUQ01CB4K7 No results 7660 JY8QFUQ01A4Y6U productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7661 JY8QFUQ01ANEIB No results 7662 JY8QFUQ01A2COT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 915 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); aggcctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcantgaGggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7663 JY8QFUQ01BE8AK productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYHYDMFGDYW in-frame + ctctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgttcggcgactactggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 7664 JY8QFUQ01AUNYM productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7665 JY8QFUQ01CY2WW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKSPSQVGYYLDCW in-frame + ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7666 JY8QFUQ01BEIG4 No results 7667 JY8QFUQ01BW0OM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccaggaaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7668 JY8QFUQ01CLADE productive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtacctttggcatgcactgggtccgccaggctcccgggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 7669 JY8QFUQ01ARAAW productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7670 JY8QFUQ01AE702 productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7671 JY8QFUQ01C1ALX No results 7672 JY8QFUQ01BYVQ0 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7673 JY8QFUQ01CO7L9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 559 78.57 143/182 nt 8 8 X 8.8.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtggaactcag 7674 JY8QFUQ01DG3UA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7675 JY8QFUQ01CTCZQ unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKAGVG*YDP#NWFDPW out-of-frame - stop codons cctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcgggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7676 JY8QFUQ01BMIJH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 893 89.59 198/221 nt 89.14 197/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); caggctctgacttGcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7677 JY8QFUQ01DDCHH No results 7678 JY8QFUQ01BYQ3F unknown (see comment) Homsap IGHV3-64*03 F, or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 179 59.4 79/133 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccc 7679 JY8QFUQ01AFKF8 No results 7680 JY8QFUQ01BYZ7A No results 7681 JY8QFUQ01CP9M3 No results 7682 JY8QFUQ01AHVIM unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7683 JY8QFUQ01A7VMJ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgGggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7684 JY8QFUQ01BCN34 productive (see comment) Homsap IGHV1-3*01 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggGggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7685 JY8QFUQ01CDKTG productive Homsap IGHV3-7*01 F 1012 96.76 209/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + tctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7686 JY8QFUQ01ABR4H productive (see comment) Homsap IGHV3-7*01 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 7 8 6 7.8.6 [1.17.37.11] CVKSIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) ctctggattcacttttagcagttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaaggtcttcccgctgagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7687 JY8QFUQ01CCMJQ No results 7688 JY8QFUQ01C70E3 unknown (see comment) Homsap IGHV4-34*12 F 91 50.97 79/155 nt 8 7 X 8.7.X [1.17.18.X] null + No rearrangement found tctgtggtgggtccttcagtggttactcctggaactgcatccgccagcccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacctcccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttcccccg 7689 JY8QFUQ01CZPWM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 7690 JY8QFUQ01BS4F0 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7691 JY8QFUQ01ASLBM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7692 JY8QFUQ01DHOOC No results 7693 JY8QFUQ01DG6B4 No results 7694 JY8QFUQ01A8T5C No results 7695 JY8QFUQ01A66AU unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 148 53.19 100/188 nt 8 7 X 8.7.X [2.17.28.X] null - No rearrangement found gcctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7696 JY8QFUQ01DDC8I productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 723 82.24 176/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7697 JY8QFUQ01A4KIH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7698 JY8QFUQ01A7LKR productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7699 JY8QFUQ01BZOTI unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7700 JY8QFUQ01DNEIO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + in FR3-IMGT at codon 90 of V-REGION: 'C' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgCcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccaggggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttc 7701 JY8QFUQ01CCYDM No results 7702 JY8QFUQ01A730W No results 7703 JY8QFUQ01C8SLA No results 7704 JY8QFUQ01AS292 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7705 JY8QFUQ01AJWQ7 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 7706 JY8QFUQ01C9VPZ unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 903 91.59 196/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [0.17.38.11] CAKAGVG*YDP#NWFDPW out-of-frame - stop codons tggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcgggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7707 JY8QFUQ01CWY2U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 7708 JY8QFUQ01AKF88 productive Homsap IGHV3-11*01 F, or Homsap IGHV3-21*04 F (see comment) 378 80.51 95/118 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 X 1 13 X.1.13 [X.X.38.11] CVREVTGVWDWFDPW in-frame + Low V-REGION identity (80,51% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcgccttcaactcagtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7709 JY8QFUQ01CIRB3 productive Homsap IGHV3-7*01 F 1012 96.76 209/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARNTPAYWELSGDW in-frame + tctggattcacctttaggagttattggatcagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaacccagatggaagtgagaaatactatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgcgaaatacaccggcgtattgggaactatcaggtgactggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7710 JY8QFUQ01CWYA5 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 687 80.37 172/214 nt 79.91 171/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccaCggcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7711 JY8QFUQ01CR7OY No results 7712 JY8QFUQ01DHO6X unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7713 JY8QFUQ01B3ASB No results 7714 JY8QFUQ01DHH8X No results 7715 JY8QFUQ01BJLXZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccAaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7716 JY8QFUQ01BCFXE productive (see comment) Homsap IGHV3-30*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [2.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7717 JY8QFUQ01C7ONV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7718 JY8QFUQ01CCHPX No results 7719 JY8QFUQ01CY1G4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7720 JY8QFUQ01BUCDU No results 7721 JY8QFUQ01DC796 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7722 JY8QFUQ01C1XF9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7723 JY8QFUQ01A4HGJ No results 7724 JY8QFUQ01A2MU9 No results 7725 JY8QFUQ01DEYBO productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 918 91.71 199/217 nt 90.32 196/217 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 8 8 19 8.8.19 [1.16.38.11] CARPAFSGSGTYRPRMAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CCT' (3 nucleotides at position 15 to 17 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tttctggatacagtCCTttagccaattactggatcggctgggtgcgccaggtgcccggaaaggcctggagtggatCggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagctttctctggttcggggacttaccggccgaggatggcttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 7726 JY8QFUQ01CPQB9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 7727 JY8QFUQ01CP37E productive Homsap IGHV3-11*01 F 923 91.74 200/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame - cctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7728 JY8QFUQ01BYYSI No results 7729 JY8QFUQ01BCMPS productive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7730 JY8QFUQ01CQGS1 No results 7731 JY8QFUQ01C2EUQ No results 7732 JY8QFUQ01DDV7L productive (see comment) Homsap IGHV3-30*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctagattcaGccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7733 JY8QFUQ01DKG44 productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7734 JY8QFUQ01BGPYT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtaaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 7735 JY8QFUQ01BR6NC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaacatggaagcgtggtcgtcgcatgcctggtccagggcttcttcccccag 7736 JY8QFUQ01BQ33P unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 671 87.86 152/173 nt 87.28 151/173 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.22.11] CTNDFQWRYVLR#AFHVW out-of-frame - in FR3-IMGT, from codon 68 of V-REGION: 48 nucleotides (from position 114 in the user submitted sequence), (do not cause frameshift) tctctggtgactccattggtagtagtgcttactactggggctgggtccgccagcccccagggaaggggctcgaatggatagggaatatttactatggtggcagcacctactacaaccagctcttcctggagctgacctctgtgaccgccgcagacacggctctttattactgtacgaacgactttcaatggcggtacgtgctacgcatgctttccatgtctggggccaagggacaatggtcgccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7737 JY8QFUQ01BR8N9 productive (see comment) Homsap IGHV2-5*02 F 874 95.31 183/192 nt 94.27 181/192 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.21.11] CAHIRAELSTSCHAFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 81 of V-REGION: 51 nucleotides (from position 172 in the user submitted sequence), (do not cause frameshift) accctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaAaggccctggagtggcttgcacttgtttattgggatgatgataagcgctacagctcatctctgaagagcagactcaccatcaccaaggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7738 JY8QFUQ01CD89E No results 7739 JY8QFUQ01CP1DZ unproductive (see comment) Homsap IGHV3-48*01 F 900 90.78 197/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame + stop codons ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccacctccagagacaatgccaggaattcactgtatctgtaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7740 JY8QFUQ01A3SN3 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7741 JY8QFUQ01AM8HH No results 7742 JY8QFUQ01AZB66 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKSFDYTNFYGLDVW in-frame + ctctggattcacttttagttactatgtcatgagttgggtccgccaggctcccgggaaggggctggagtgggtctcaggtattagtggtattggtgataccgcatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaaggacacactgattctgcaaatgaacagtctgagagccgaggacacggccacttattattgtgcgaagtccttcgactatactaacttctatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcctcaccaagggcccagtcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7743 JY8QFUQ01DIRD2 productive Homsap IGHV3-30*01 F 873 89.4 194/217 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7744 JY8QFUQ01BZQC5 productive (see comment) Homsap IGHV4-61*03 F (see comment) 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD4-17*01 F 2 8 7 13 8.7.13 [1.17.37.11] CARNDHGMWDAFHLW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01BZQC5 ; 10 AA in Homsap_IGHV4-61*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 211 in the user submitted sequence), (cause frameshift) tctctggtgactctatggcaagctattactggagttggctccggcagcccccaggggagagactggaatggattgggtacatatattccactgggagcaccaactacaacccctcctttaagagtcgagtcaccatttcaatagacaccccgaagaaccacctctccctgaaattgaaatctgtgaccgctgcagacacggccgtgtattttgtgcgaggaacgaccacggtatgtgggatgcatttcatctctggggccaagggacactggtcaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaccgtgacggtgtcgtggaactc 7745 JY8QFUQ01DGA30 productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame - tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7746 JY8QFUQ01B76BW productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7747 JY8QFUQ01AEM2N productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame + ctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7748 JY8QFUQ01AFJ2C No results 7749 JY8QFUQ01BQV85 No results 7750 JY8QFUQ01C8XGF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7751 JY8QFUQ01B0IGY unproductive Homsap IGHV3-7*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERSAAGVVFFDF# out-of-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagcccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7752 JY8QFUQ01A51EO No results 7753 JY8QFUQ01A70EP productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + tggatacaccttcagcgactactacatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggctgaaccctaataatggtgacacagcttatggccagagctttcagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggcttttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7754 JY8QFUQ01CET2Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 983 87.16 224/257 nt 86.77 223/257 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [14.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 22 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); cgagtgcgtggagggggcccctgagactctCcctgtgcagcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7755 JY8QFUQ01ASDQE productive (see comment) Homsap IGHV3-74*03 F (see comment) 702 80.65 175/217 nt 80.18 174/217 nt Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTTGWRGVDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcaacgtcagtggatactggatgcactgggtccgccaagtgccagggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7756 JY8QFUQ01C77FN No results 7757 JY8QFUQ01CLD99 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 882 89.86 195/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD1-1*01 F 3 8 8 18 8.8.18 [1.17.38.11] CATLNAHAGPGAEWSAFDIW in-frame + ctctggattcagcttcagtctctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcctccattactagtaacagtgattacatatactatgctgactcagtgagaggccgattcaccatctccagagacaactccaagaagtcactgtttctgcaaatgcacagcctgagagccgacgacacggctatctactactgtgcgaccctaaacgcgcacgcgggaccgggagccgaatggtctgcttttgacatctggggccatgggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 7758 JY8QFUQ01ADH3W productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 7759 JY8QFUQ01BX8RV No results 7760 JY8QFUQ01BWF5H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 798 85.0 187/220 nt 84.55 186/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRVKRFGSGNVLFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); aggctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaAagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7761 JY8QFUQ01A9YIB productive Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CGRIAKPGLGALDLW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7762 JY8QFUQ01A5ATC productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 7763 JY8QFUQ01C42A6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7764 JY8QFUQ01B8WYR No results 7765 JY8QFUQ01B8JYP productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.16.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7766 JY8QFUQ01B5CHG No results 7767 JY8QFUQ01BB80V productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + ctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 7768 JY8QFUQ01BGMBI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame + ctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7769 JY8QFUQ01BTJVV unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca 7770 JY8QFUQ01BIBQD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7771 JY8QFUQ01CN3GP unknown (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgGggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaatttacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactgggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7772 JY8QFUQ01DECQJ No results 7773 JY8QFUQ01DBPKB unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ6*01 F (see comment) 94 61.29 38/62 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7774 JY8QFUQ01CQO2W productive Homsap IGHV4-4*07 F (see comment) 710 80.93 174/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 16 10.7.16 [1.17.38.11] WARECLDSLGRPSHLDSW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CQO2W ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,93% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggcccgatcaagaatactgactactattggacatggatccggcagcccgccgggaggggactggagtgggtcgggcgtgtctatttgaatggcaatgccgactacaacccctccttcagcagccgtctcaccatgtccattgacacgtccaggaaccaattctccctgagcttgacctctgtgaccgccgctgacacggccctctattactgggcgagagaatgtcttgattcacttggcagaccgagtcaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7775 JY8QFUQ01AYFLL unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 110 65.52 38/58 nt 8 X X 8.X.X [1.10.X.X] null - No rearrangement found ctccggattcacctttagtagtttctggatgcactgggtccagggcttccttccccca 7776 JY8QFUQ01B06FJ No results 7777 JY8QFUQ01ACGK8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.5 206/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtctcccgctgagctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 7778 JY8QFUQ01DQ3B6 No results 7779 JY8QFUQ01DW90Z No results 7780 JY8QFUQ01CLXUH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggggcttcttccccca 7781 JY8QFUQ01A5S7Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7782 JY8QFUQ01BRKZU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BRKZU ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7783 JY8QFUQ01BYXV7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-11*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARASLTKTNFDYW in-frame + tctggattcaccttcagaagttatagcattaactggttccgtcaagctccaggggagggcctggagtgggtctcatccattagtagtaccagttcttacatttactacgcagactcagcgaggggccgattcaccatctccagagacaacgccaataactcagtgtctctgcaaatgaacggcctgagagccgatgacacggctctatatttttgtgcgagagcttccctcactaagacaaactttgactactggggcccgggaacgctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7784 JY8QFUQ01B36Z3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 7785 JY8QFUQ01CH1L2 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7786 JY8QFUQ01B47WM productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 87.78 194/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame - tctctggtggctccatcaccggaagtagttattattggggctggattcgccagtccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7787 JY8QFUQ01BTVX2 No results 7788 JY8QFUQ01C0XDT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaagggctggagtgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7789 JY8QFUQ01B0E54 productive Homsap IGHV3-30*10 F (see comment) 724 81.94 177/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 7790 JY8QFUQ01B9PYF productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARWGATWELLLGNLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacGaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagatggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7791 JY8QFUQ01AKG3P productive Homsap IGHV4-61*02 F 929 91.4 202/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARATLSDVDTPLGFDYW in-frame + tctctggtgtctcaatcacgagtggaagtcactactggaattggattcggcagcccgccgggaagggaccggagtggattgggcgtttctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccgtatcagcagacacgtccaagaaccggctctccctgaagctgagatctttgaccgccgcagacacggctgtttattactgtgcgagagcaaccttgtctgacgtggatacacctttgggctttgactactggggccagggaatcttggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 7792 JY8QFUQ01DP731 unproductive (see comment) Homsap IGHV3-9*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAK*YWGIHMWTIDYW in-frame + stop codons cctctggattcacgtttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaaatgatattgggggatacacatgtggaccattgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggctcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 7793 JY8QFUQ01C48H7 productive (see comment) Homsap IGHV3-7*01 F 882 91.83 191/208 nt 91.35 190/208 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*02 F 2 6 8 14 6.8.14 [X.17.38.11] CARGSYYHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'T' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); tcactttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaaaTgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcaatatatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattatcattatgacaccttcggcgactattggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7794 JY8QFUQ01CJMPT productive (see comment) Homsap IGHV3-11*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7795 JY8QFUQ01BZSKZ productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7796 JY8QFUQ01AL0S2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 828 87.1 189/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); tgtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggCaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7797 JY8QFUQ01C34Q3 unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 161 54.49 97/178 nt 8 7 X 8.7.X [1.17.25.X] null - No rearrangement found cctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7798 JY8QFUQ01C2XW9 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame - ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7799 JY8QFUQ01B83CF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7800 JY8QFUQ01BMUMM No results 7801 JY8QFUQ01ATS6F productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + ttctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7802 JY8QFUQ01B7RE7 productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7803 JY8QFUQ01BG0ZX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcgaccctgggctgcctggtcaaggactacttccccgaaccggtgacggtntcgtggaactca 7804 JY8QFUQ01AP5BZ No results 7805 JY8QFUQ01CQ57N productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7806 JY8QFUQ01B1PFE unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7807 JY8QFUQ01BU0AP No results 7808 JY8QFUQ01BC1SJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 7809 JY8QFUQ01A0HBC unknown (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7810 JY8QFUQ01AR2I9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7811 JY8QFUQ01DLM3X productive (see comment) Homsap IGHV2-5*02 F 1152 97.13 237/244 nt 95.9 234/244 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 10 7 15 10.7.15 [9.17.38.11] CAQKGEIDTYGPKYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'AC' (2 nucleotides at position 189 to 190 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagcactagtggagtGgggtgtgggctgcatccgtcagGcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagtccatctctgaagagcagactcaccatcaccaaggacacctccaaaaaACcagggtggtccttacaatgaccaacatgaaccctatggacacagccacatattactgtgcacagaagggggaaatagacacctatggccccaaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 7812 JY8QFUQ01DCW6Z No results 7813 JY8QFUQ01DLZFY unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 100 66.67 32/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame + stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtntcctcagatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 7814 JY8QFUQ01B41S4 unknown (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggtcgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7815 JY8QFUQ01BJS3C unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 277 62.87 105/167 nt 8 10 X 8.10.X [2.17.20.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01BJS3C ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7816 JY8QFUQ01CAXWI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 203 93.48 43/46 nt 8 X X 8.X.X [1.6.X.X] null - No rearrangement found ctctggattcagatttagcagctatggcatgagctgggtccgccag 7817 JY8QFUQ01B32WV unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 121 54.48 73/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons gtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7818 JY8QFUQ01AV8RW productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7819 JY8QFUQ01C185F productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 818 85.27 191/224 nt 84.82 190/224 nt Homsap IGHJ5*02 F 110 69.39 34/49 nt Homsap IGHD1-26*01 F 2 8 10 5 8.10.5 [1.17.38.11] CREAIAW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctgggttcgtgttcggtaacttctttatgaattggttccgccagcctccgggaaAaggggctggagtgggttggccgcatcaaaaccaaagttgatggtgagacaacagactacgctgcagccgtgaaagacagattcatcatttcaagagatgattcaaaaaatacgatgtatctgcaaatgaacgacctgaagaccgaggacacggccgtatattattgtcgggaggccatcgcgtggggccagggaaccctggtcaaggtctcatcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7820 JY8QFUQ01B0MQR productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7821 JY8QFUQ01BR1K2 productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7822 JY8QFUQ01C79FO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt 96.74 208/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtggGgagcaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7823 JY8QFUQ01AJ94F productive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 7 8 6 7.8.6 [1.17.38.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg 7824 JY8QFUQ01ATLE6 No results 7825 JY8QFUQ01B0H63 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7826 JY8QFUQ01AW1RT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7827 JY8QFUQ01ACX8S No results 7828 JY8QFUQ01AUJ6M productive (see comment) Homsap IGHV3-7*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctacattcacgtttagtcggtattggatgagctggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7829 JY8QFUQ01BEKUJ unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 82 53.47 54/101 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons ctctggattcaccgtcagagataactacgtgacctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccac 7830 JY8QFUQ01C3FFW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7831 JY8QFUQ01CAPJ8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7832 JY8QFUQ01AXSRV unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7833 JY8QFUQ01AXU31 productive Homsap IGHV3-23*05 F, or Homsap IGHV3-66*03 F or Homsap IGHV3-NL1*01 F (see comment) 387 78.74 100/127 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 X 4 9 X.4.9 [X.X.38.11] CARDQVTEDYW in-frame - Low V-REGION identity (78,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctacattcgcctttagcaactatgccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7834 JY8QFUQ01BJDMV No results 7835 JY8QFUQ01BY9B6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 8 14 8.8.14 [1.17.38.11] CAKVGVMSARDRIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtgggggtgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7836 JY8QFUQ01BQOVD No results 7837 JY8QFUQ01BMC7N productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 829 86.76 190/219 nt 85.39 187/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactggGgtccggcaagttccCAaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7838 JY8QFUQ01BPXZS productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7839 JY8QFUQ01DIM81 productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7840 JY8QFUQ01A3NLN productive (see comment) Homsap IGHV3-7*01 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7841 JY8QFUQ01AFX9B No results 7842 JY8QFUQ01CE8P9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7843 JY8QFUQ01BMCQC unproductive (see comment) Homsap IGHV3-72*01 F 823 85.33 192/225 nt 84.44 190/225 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [2.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); acctcagggttcgctttttgagaAatacaccatgagttgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaAagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7844 JY8QFUQ01BMES9 No results 7845 JY8QFUQ01CDC8F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7846 JY8QFUQ01BK1FK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1040 97.71 213/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 7847 JY8QFUQ01A0DHK unknown (see comment) Homsap IGHV3-23*03 F (see comment) 253 78.31 65/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (78,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggtccagggcttcttccccca 7848 JY8QFUQ01CK11N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.24 188/218 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggantgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7849 JY8QFUQ01BVH2P No results 7850 JY8QFUQ01AUQ27 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagaaaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 7851 JY8QFUQ01AO88B No results 7852 JY8QFUQ01AGJ8R No results 7853 JY8QFUQ01CXWNZ No results 7854 JY8QFUQ01A95LP No results 7855 JY8QFUQ01CSQWT No results 7856 JY8QFUQ01DFD03 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARKRVPGGDFFMG##YW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccgggggggacttttttatgggggaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7857 JY8QFUQ01A9QZP unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgcttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaagtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7858 JY8QFUQ01A3VWR No results 7859 JY8QFUQ01BLT2J productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 986 94.95 207/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7860 JY8QFUQ01CYKN1 No results 7861 JY8QFUQ01C4L9S unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFLW#DYW out-of-frame - cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggacctttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7862 JY8QFUQ01ANTCO productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7863 JY8QFUQ01DOR32 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7864 JY8QFUQ01AF1BX No results 7865 JY8QFUQ01ASIM9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 971 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); tctggattcactttcagnagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacaGccctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcatcccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7866 JY8QFUQ01BVO71 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7867 JY8QFUQ01CFU9Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 15 7.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7868 JY8QFUQ01A34ZH productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 3 8 8 19 8.8.19 [1.17.38.11] CARLPFIVVVTGAFLGHFDYW in-frame - gttctggatacacgtttatgaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7869 JY8QFUQ01AWT78 productive (see comment) Homsap IGHV1-24*01 F 952 94.37 201/213 nt 93.9 200/213 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [X.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7870 JY8QFUQ01DCFJM productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 7871 JY8QFUQ01DL2T3 No results 7872 JY8QFUQ01AUVXR productive Homsap IGHV3-48*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVPGPNDNYFDYW in-frame + ctctggattcagcttcagagactatggcatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatacattggtaggattattagtgacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagggacgacgacacggctgtctatttctgtgcgagagatgtcccgggccccaatgacaactactttgactactggggccagggaaccctgcttaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccca 7873 JY8QFUQ01B19Q4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 590 89.73 131/146 nt 89.04 130/146 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 6 X 8.6.X [1.17.16.11] CAKKYHYGSGSYLYSFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 71 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctgggttcacctttgcccactttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtggtgatgattccacaaatggacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactcctttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaagggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7874 JY8QFUQ01BF6QF unproductive Homsap IGHV4-39*02 F (see comment) 704 80.09 177/221 nt 79.64 176/221 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-10*01 F 3 10 7 X 10.7.X [1.17.38.11] CAIHNYYGSGRNYFDH## out-of-frame - Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggagtctccgccatcggcaccagttccttctAggggctgggtccgccagcccccagggaaggggctggagtggatcggagctgttcattacagtggaagtatctcttacacgccggccctcaagagtcgactcaccatgtccttagacacgtcaaaaggtcacttgtccctgagactgacctcagtgacctccgcagacacggctatgtactactgtgccatacacaactactatggatcggggagaaactactttgaccactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7875 JY8QFUQ01DE9OH No results 7876 JY8QFUQ01A3QYQ No results 7877 JY8QFUQ01CT5W5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFTYAFDLW in-frame + cgtctggattcacgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7878 JY8QFUQ01BL4EI productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ggcctcctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7879 JY8QFUQ01BG66X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVYTGAWGDPNFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtacttttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7880 JY8QFUQ01DRDEK unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYXGLDV## out-of-frame - in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataGggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattacnctggtctggacgtctggggccgaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7881 JY8QFUQ01A8M23 No results 7882 JY8QFUQ01AGECL unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 X 10.9.X [1.17.38.11] CARGVIIMIVVV#DYW out-of-frame - tctcgggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagaggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7883 JY8QFUQ01BK6SR No results 7884 JY8QFUQ01C4C3G productive (see comment) Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7885 JY8QFUQ01C8XAC productive (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaAaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 7886 JY8QFUQ01DL701 No results 7887 JY8QFUQ01BFRHA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7888 JY8QFUQ01CGDK6 productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7889 JY8QFUQ01DK30C unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 828 87.1 189/217 nt 86.18 187/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-6*01 F 2 7 7 X 7.7.X [2.17.38.11] CVRSYSRTSEFDY## out-of-frame - in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) gcgtctggattcagttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggactcaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggccccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7890 JY8QFUQ01C6FNP No results 7891 JY8QFUQ01CT9X8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7892 JY8QFUQ01ARPA7 No results 7893 JY8QFUQ01BG3AX productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaaGgttcatgagctgggtccgccaggctccagggaaTggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7894 JY8QFUQ01AM5G9 No results 7895 JY8QFUQ01AIRZ3 productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7896 JY8QFUQ01BGDYH unproductive Homsap IGHV3-NL1*01 F (see comment) 312 70.77 92/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 X 5 X X.5.X [X.X.38.11] VREIPYLGRQRL#YHFDYW out-of-frame + Low V-REGION identity (70,77% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattctccttcagaagttactctttccactggggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttattttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7897 JY8QFUQ01BETIR productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7898 JY8QFUQ01C5ZGW productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7899 JY8QFUQ01CWFYY No results 7900 JY8QFUQ01CR93I No results 7901 JY8QFUQ01CTXUJ productive Homsap IGHV4-59*02 F 930 92.99 199/214 nt Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD4-23*01 ORF 3 8 7 15 8.7.15 [1.17.38.11] CARRFTVERGKDAFDIW in-frame + ctctggtggctccgtcactaataactactggagctggatccggcagcccccagggatgggactggagtggattgggtatatccataacagtgggacctccaactacaacccctccctcaagagtcgagtcaccatatcactagacacgtccaagagccagttctccctgaacctggggtctgtgaccgccgcggacacggccgtctattactgtgcgagacgctttacggtggagaggggaaaagatgcttttgatatctggggccacgggacaatggtcaccgtgctcttcagcctccaccaagggcccatggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 7902 JY8QFUQ01DW9T6 productive (see comment) Homsap IGHV3-33*04 F (see comment) 684 79.72 173/217 nt 78.8 171/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'AC' (2 nucleotides at position 207 to 208 in the user submitted sequence), (cause frameshift); atttggattccctttcagcgactatggcatgcactGgggtccgccaggctccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctACtttacttattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7903 JY8QFUQ01A476X productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGKMVSTGMDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattcacgtttagtgactactacatgacctggattcgtcaggctccagggaagggcctggagtgggttacatatattagtagtagtggtggtaacacacattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 7904 JY8QFUQ01BAR1C productive Homsap IGHV3-9*01 F 891 90.32 196/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 8 8 26 8.8.26 [1.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcacctttgatgattttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7905 JY8QFUQ01CAD79 No results 7906 JY8QFUQ01CCPYE unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - stop codons ctctgattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7907 JY8QFUQ01BS51T productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7908 JY8QFUQ01BQU68 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKEEGATGVYYVDH# out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagAccctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7909 JY8QFUQ01DPLFH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame - Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7910 JY8QFUQ01DDRAT unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagccgtccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccttgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 7911 JY8QFUQ01CDUPC No results 7912 JY8QFUQ01AAXU5 No results 7913 JY8QFUQ01CNDRT unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1044 98.16 213/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CANYYDSSGYRD* in-frame + stop codons ctctggattcacctttagaagttatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtagtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaattattatgatagtagtggttatagagactagggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 7914 JY8QFUQ01AHBK2 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7915 JY8QFUQ01BRBQF No results 7916 JY8QFUQ01AWTSB No results 7917 JY8QFUQ01A6QOY No results 7918 JY8QFUQ01B4DMT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ttctggattcgcctttagccgttatgccatgacttgg 7919 JY8QFUQ01BF7VE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7920 JY8QFUQ01CW1LU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggacccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7921 JY8QFUQ01B8L20 No results 7922 JY8QFUQ01A5SGC unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-10*01 F 3 7 8 X 7.8.X [1.17.38.11] CVRRGMVAGRYD##FDIW out-of-frame - stop codons in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) cctctggatcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcagccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgccttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7923 JY8QFUQ01B3L4U productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7924 JY8QFUQ01BISI7 productive Homsap IGHV3-30*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYEDCRGGRCYAEPLDYW in-frame + cctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagattacgaggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 7925 JY8QFUQ01DOA8W productive (see comment) Homsap IGHV3-30*01 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 7 8 11 7.8.11 [2.17.38.11] CACGHMRDGYDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtgccttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtCaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7926 JY8QFUQ01DF6DK unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDAFDV# out-of-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaaggacaatggtcaccgtctctcagcattccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7927 JY8QFUQ01CJP19 productive Homsap IGHV3-9*01 F 1036 97.26 213/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-20*01 F 3 8 8 13 8.8.13 [2.17.38.11] CAKDMGYTWKYIDHW in-frame - gcctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7928 JY8QFUQ01CD227 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7929 JY8QFUQ01C3KNU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaagacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7930 JY8QFUQ01CMPV8 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1015 95.5 212/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARHPLGESFFEYW in-frame - gtctctggtggctccatcagcagtggcgcttactactggagctggatccgccagcacccagggaagggcctggagtggattgggcacatctatgacagtgggagcaccaactacaacccgtccctcaagagtcgagtttccatatcaatagacacgtctaagagccacttctccctgaagctgagctctgtgactgccgcggacacggccgtgtatttctgtgcgagacatccgcttggggagagcttctttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7931 JY8QFUQ01AMZO0 No results 7932 JY8QFUQ01AH6R0 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 914 93.3 195/209 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 6 8 18 6.8.18 [X.17.38.11] CARHRDYGGQSWFYHGMDVW in-frame + atagtttcaccagatactgggtcggctgggtgcgccagatgcccgggaaaggcccggagtggatggggatcatctatcctgatgactctgataccagatacagtccgtccttcaaaggccaggtcaccatctcagccgacaagtccatcagtaccgcctacctgcagtggaacagcttgaaggcctcggacaccgccttgtattattgtgcgagacatagggactacggtggtcaatcctggttctaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7933 JY8QFUQ01CJBM7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7934 JY8QFUQ01B3GJ1 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1023 96.36 212/220 nt 95.91 211/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARPGVGASSFIDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gggttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7935 JY8QFUQ01BYV6J No results 7936 JY8QFUQ01DB0H7 No results 7937 JY8QFUQ01DVVCU unknown (see comment) Homsap IGHV3-7*02 F 914 91.28 199/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaacgactactggggccagggaaccctgggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactcttcccccgaaccgggtgacggtgtcgtggaacctcagg 7938 JY8QFUQ01CB0IE No results 7939 JY8QFUQ01CG6HK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagGggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7940 JY8QFUQ01B6DDX productive Homsap IGHV3-7*03 F 846 88.02 191/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 7941 JY8QFUQ01DUA1Y productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7942 JY8QFUQ01CGXPC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcggatgactcga 7943 JY8QFUQ01CS5I4 No results 7944 JY8QFUQ01B2WQ3 No results 7945 JY8QFUQ01AXL0Y unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 1 8 7 X 8.7.X [2.17.38.11] CARGVGQQLPPLD## out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); gtctctcgtgcctccatcaatacCtttttactGggagctggatccggcagcccccagggaagggactggagtggattggatatatctatgatagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggggtggggcagcaactgccccccttagactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7946 JY8QFUQ01BJB2Q No results 7947 JY8QFUQ01DEDM3 productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1020 95.52 213/223 nt 94.17 210/223 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-15*01 F 3 8 10 19 8.10.19 [1.17.38.11] CARHGRDSSEVMVGGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'G' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtggctctgctatgcactgggtccgccaggcttccgggaAaagggctggaatgggttggccgtattagaagcagagcttacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtGatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatggaagggactccagtgaagtgatggtaggtggatacggcatggacgtctggggccaagggtccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7948 JY8QFUQ01ALNIQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 266 67.72 86/127 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (67,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7949 JY8QFUQ01B0042 No results 7950 JY8QFUQ01C5QTX productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7951 JY8QFUQ01DLKL1 productive (see comment) Homsap IGHV3-48*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggTtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7952 JY8QFUQ01CM1OS No results 7953 JY8QFUQ01AL23O No results 7954 JY8QFUQ01AS3JQ unproductive Homsap IGHV3-48*01 F 896 90.37 197/218 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [1.17.38.11] CARESTWEFTPDS## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccgggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7955 JY8QFUQ01BCEKR unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 7956 JY8QFUQ01A8GCA No results 7957 JY8QFUQ01BMTRL unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttccccca 7958 JY8QFUQ01BTQ0D productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7959 JY8QFUQ01BRZ9W unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.16.38.11] CAKDRITIF#YNWFDPW out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatatttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7960 JY8QFUQ01DQSAI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 7961 JY8QFUQ01CCAFD productive (see comment) Homsap IGHV4-61*02 F (see comment) 568 73.18 161/220 nt 72.27 159/220 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.16.38.11] CARECSNSKVGPRALDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (73,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagccnccgggaaggggctggagtgggtcgggcgtgtctatatgactggctatgtcgagaacaatccatccctctccgggcgtctctccatgtcgattgacacggcgaagaatcagttttctatgacattgacttctgtgaccgccgcagacacggccctttaAtttttgtgcgagggagtgtagtaattcgaaagtcggaccgagagcgcttgactcctggggcccgggaagtctggtcaccgtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7962 JY8QFUQ01AI6TS No results 7963 JY8QFUQ01A5WTA No results 7964 JY8QFUQ01CAQFC unknown (see comment) Homsap IGHV3-7*03 F 837 87.1 189/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcatgtttagtaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggtagtgagacttactatgtggaatctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7965 JY8QFUQ01C6JPE productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7966 JY8QFUQ01B6CY0 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-22*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAGRNGNLAFNIW in-frame + atctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggagatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaaattgacttctgtgaccgccgcggacacggccatatattactgtgcgggaagaaatggaaatttggccttcaatatttggggccaagggacaaatgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7967 JY8QFUQ01BU37Y No results 7968 JY8QFUQ01CSBH4 productive Homsap IGHV3-7*01 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - gcctctggcttcacctttgaaaattatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7969 JY8QFUQ01C20VU productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7970 JY8QFUQ01DSS92 No results 7971 JY8QFUQ01BQ2BT No results 7972 JY8QFUQ01BSZ5N No results 7973 JY8QFUQ01AWVZM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 7974 JY8QFUQ01BAN3Z No results 7975 JY8QFUQ01C2FP7 unproductive Homsap IGHV3-7*01 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGAGAEGKGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); tagcctctggattcacctttagtaattattggatgagctgggtccgccaggctccagggaagggactggagtgggtggccaatataaagcaagatggaagtaagaagcactatgtggactccgtggagggccgattcaccatcaccagagacaacaccaaaaGactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7976 JY8QFUQ01B8GND No results 7977 JY8QFUQ01CS6B3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 870 88.64 195/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame - ctctggtgactccattggtagcagtgcctactactggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7978 JY8QFUQ01BKHHN productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7979 JY8QFUQ01CORR8 No results 7980 JY8QFUQ01CSE5B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 912 92.06 197/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 3 8 8 12 8.8.12 [1.17.37.11] CAKGRGVTRYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 86 of V-REGION: 3 nucleotides (from position 161 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcgactatctcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgagtattagtggtagtgatggtaccacatattacgcagactccgtgaagggccggttcaccttctccagagacaattccaagaagatgtatttgcaaatgaacaccctgagagtcgaggacacggccgtatattactgtgcgaaaggacggggcgtcacccggtactttgactactggggccagggagccctggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 7981 JY8QFUQ01B4UWJ No results 7982 JY8QFUQ01A7B3N unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactaCggccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7983 JY8QFUQ01BLT04 productive (see comment) Homsap IGHV3-7*01 F 1014 95.91 211/220 nt 95.45 210/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); aggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7984 JY8QFUQ01ASQ0V productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7985 JY8QFUQ01DRCXR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7986 JY8QFUQ01DT1WQ productive (see comment) Homsap IGHV3-7*03 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [2.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaAaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7987 JY8QFUQ01C0C6D unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 432 92.93 92/99 nt 91.92 91/99 nt 8 7 X 8.7.X [1.16.X.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtaggggtgttgaca 7988 JY8QFUQ01B3AFX No results 7989 JY8QFUQ01AY29M unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 93 52.27 69/132 nt 8 6 X 8.6.X [1.17.11.X] null + No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 7990 JY8QFUQ01B8PWI unproductive Homsap IGHV3-7*01 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKARIYFMVRGVIP#FDYW out-of-frame + tctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctattttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7991 JY8QFUQ01AJFHX unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga 7992 JY8QFUQ01DHQ9W productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 7993 JY8QFUQ01ABF66 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7994 JY8QFUQ01BHEKS unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 814 86.57 187/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 1 8 7 X 8.7.X [2.17.38.11] CGTSSRAWA#DAFDIW out-of-frame - gcctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctgggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 7995 JY8QFUQ01AD5WM productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7996 JY8QFUQ01AFPP1 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 993 96.26 206/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found tgaatacagttttaccagttcctggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagtccgtccttcaaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgagggcctcggacaccgccatgtattactgtgcgggcactcaagtgggagctaagggggggattccactggttcttcgatttctggggtcccgtggcacccctggtcactggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 7997 JY8QFUQ01CNHUT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 7998 JY8QFUQ01C0HRE productive Homsap IGHV3-11*01 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - tctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 7999 JY8QFUQ01AFM6J No results 8000 JY8QFUQ01BJQFO No results 8001 JY8QFUQ01DADSF No results 8002 JY8QFUQ01A6VPK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8003 JY8QFUQ01CFJ2D No results 8004 JY8QFUQ01AWP5I productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 8005 JY8QFUQ01B7OCJ No results 8006 JY8QFUQ01CIP7Q unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 783 84.33 183/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8007 JY8QFUQ01DOVL5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8008 JY8QFUQ01DSAKD productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8009 JY8QFUQ01CBVQ5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARQSVPYTEYFNWFDPW in-frame + gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcagggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagagccgaggacacggctgtgtattattgtgcgagacagtctgtaccatataccgaatatttcaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8010 JY8QFUQ01BR5YQ No results 8011 JY8QFUQ01DRZGS No results 8012 JY8QFUQ01CUVWM unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGPL# out-of-frame + ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggcccactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8013 JY8QFUQ01B19RC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 8014 JY8QFUQ01BKWOZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattcccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8015 JY8QFUQ01ALBIK unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDLRARLWHPMDV# out-of-frame + ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctgggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 8016 JY8QFUQ01BFWPX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 930 91.03 203/223 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [3.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tgtagcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8017 JY8QFUQ01AG86T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8018 JY8QFUQ01AQZD7 productive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.16.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) tctctggtggccccatcagcagcagcacttactactggacttggatGccggcaggccgccgggagggactggagtggatcggacgtgtttatactTagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8019 JY8QFUQ01CRMUC unproductive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8020 JY8QFUQ01A6GU8 unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8021 JY8QFUQ01COR9K unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKS*LW#YYFDQW out-of-frame + stop codons ctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaatcatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8022 JY8QFUQ01ATZYG No results 8023 JY8QFUQ01COYRM productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8024 JY8QFUQ01A4OAA No results 8025 JY8QFUQ01AMKU1 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 200 59.46 88/148 nt 8 8 X 8.8.X [1.17.15.X] null + No rearrangement found tctggattcacctttgacagccatgccatgcactgggtccgtcgggctccagggaaggggctggagtgggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8026 JY8QFUQ01DCBVS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 8 10 8.8.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttctccgaaccggtgacggtgtcgtggaactcag 8027 JY8QFUQ01DHDYL productive (see comment) Homsap IGHV3-69-1*02 P 919 93.33 196/210 nt 92.86 195/210 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 7 10 8.7.10 [1.16.38.11] CARDDKWAFDYW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 76 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcagtgactacagcatgaactgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8028 JY8QFUQ01C5FW0 No results 8029 JY8QFUQ01BPKJH No results 8030 JY8QFUQ01DBDVA productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 8031 JY8QFUQ01CHSF6 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8032 JY8QFUQ01A3C67 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgttatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccggctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8033 JY8QFUQ01CY0SI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctgatcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8034 JY8QFUQ01CTNMI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8035 JY8QFUQ01CQ95F productive Homsap IGHV3-9*01 F 968 93.58 204/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDAMGGAGDWAAFGIW in-frame - cctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8036 JY8QFUQ01B1HSK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8037 JY8QFUQ01AAW8M No results 8038 JY8QFUQ01CNTH5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [2.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8039 JY8QFUQ01AZUMD No results 8040 JY8QFUQ01BJUKC productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1038 98.6 211/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8041 JY8QFUQ01BGUH5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 973 94.06 206/219 nt Homsap IGHJ6*02 F 212 87.27 48/55 nt 8 8 10 8.8.10 [2.17.38.11] CARDRYYVVDVW in-frame - gcctctggattcaccttcagtgccacctggatgcactgggtccgccaagctccagggcaggggctggtgtgggtctctcatattaatggtgatgggagtagcacaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatttgcaaatgaacagtctgagagccgaggacacggctgtatactactgtgcaagagatcgatactacgttgtggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8042 JY8QFUQ01C06U8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggGtattagtggtagtggtgataGgaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8043 JY8QFUQ01CU10Q No results 8044 JY8QFUQ01BCBNG productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 8045 JY8QFUQ01AHKNO productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDLYDSSGSFDYW in-frame + ctctggattcaccttcagcagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtaggagtagtaccaaaaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagatttgtatgatagtagtggttcttttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8046 JY8QFUQ01C1IUN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8047 JY8QFUQ01CXU56 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8048 JY8QFUQ01B9YQF No results 8049 JY8QFUQ01CFUNF unproductive Homsap IGHV3-48*04 F (see comment) 939 93.46 200/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-13*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGRIVSVGMSG#FDPW out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CFUNF ; 8 AA in Homsap_IGHV3-48*04) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctgttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8050 JY8QFUQ01AC900 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8051 JY8QFUQ01AJYVB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8052 JY8QFUQ01CDH83 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CARLTTAVGGWS#LDIW out-of-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttggatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggttcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcancgcctgcctggtcagggccttccttccc 8053 JY8QFUQ01B12N8 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F 881 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-9*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDRRISAGYYDFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); gtctctggtggcGtccatcaatacgcactactggagttggatccggnagaccccagggaagggactggagtggattggatatatccatcacagtgggtacactaactacagcccctccctcaagagtcgagccaccatatcattagacacgtcgaagaaccagttctccctgaaactgggctttgtgaccgccgcggacacggccgtttattactgtgcgagagaccgtaggatttcggctggttattatgactttgatatctggggccaagggacaatggtcatcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 8054 JY8QFUQ01A18YR productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 891 90.32 196/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-9*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGGVDILTGFYDAFDIW in-frame + ttctggatacagctttggcaccgcctggctcggctgggtgcgccagacgcccgggaaaggcctggagtggatggggaccatccatcctgctgactctgatacaaaatacagcccgtccttccaggcccaagtcaccatctcggtcgacaggtccatcaacaccgcctacctgcagtggagcagcctggaggcctcggacaccgccatgtatttctgtgcgcggggaggagtcgatattttgactggtttctatgatgctttcgatatctggggccaagggaccatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 8055 JY8QFUQ01CMVZ1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8056 JY8QFUQ01ARMWR unknown (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 809 86.51 186/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctggagacaccttcagtagccaagccatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggcgggatcatccctatttttgatatgacgaggtacccacagaggttcgagggcagaatcacgattaccgcggacacgtccacgaccacactttacatggaactgagcagcctgaggtctgaggacacggccgtgtatttttgtgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8057 JY8QFUQ01BI60V unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8058 JY8QFUQ01CTJ46 productive Homsap IGHV3-30*01 F 815 86.24 188/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDFDTDDVGTYW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggattcatcttcgatagttatgctctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttgtttcatatgatggaaaatataagcaatatgcagattctgtggagggccgattcaccatctccagagacaactccaagaacacaggatatctgcaaatgaacagcctgacatctgacgatacggctgtgtatttttgtgcgagagacttcgatactgacgacgtgggcacctactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8059 JY8QFUQ01CNNKZ unknown (see comment) Homsap IGHV3-7*02 F 182 79.31 46/58 nt 8 X X 8.X.X [1.10.X.X] null - No rearrangement found ctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttcccca 8060 JY8QFUQ01CRI2C No results 8061 JY8QFUQ01DWXUL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 396 77.04 104/135 nt 76.3 103/135 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found Low V-REGION identity (77,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8062 JY8QFUQ01CH5IG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8063 JY8QFUQ01CYG8J No results 8064 JY8QFUQ01BVES5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 76 60.38 32/53 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKENYFESSGYHGMN#LG out-of-frame + ctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccagggggtaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 8065 JY8QFUQ01B7EJZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8066 JY8QFUQ01C3AE4 productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8067 JY8QFUQ01C1M1T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8068 JY8QFUQ01BSEFR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 140 78.26 36/46 nt 8 X X 8.X.X [1.6.X.X] null - No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgccag 8069 JY8QFUQ01BB900 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 8070 JY8QFUQ01CUSF5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8071 JY8QFUQ01AF7VN unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8072 JY8QFUQ01A9FXS productive (see comment) Homsap IGHV3-48*03 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8073 JY8QFUQ01DRVVN productive Homsap IGHV1-69*02 F 836 87.91 189/215 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD2-8*01 F 2 8 8 20 8.8.20 [0.17.38.11] CARGYCTNGVCYRGSYNWLDPW in-frame - tggagggcccctccggcagttataccatcaactgggtgcgacaggcccctggacaagaccttgagtggatgggaaggatcatccctacccttggcatagtaaactacgcacagaagttccagagcagagtaacgattaccgcggacaagtggacgagcacaatcttcatggagctgagcaacctgagacctgaggacacggccgtgtattattgtgcgagaggatattgtactaatggtgtgtgttatcgcggctcgtacaactggctcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8074 JY8QFUQ01C8AM7 No results 8075 JY8QFUQ01BURT1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + tccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8076 JY8QFUQ01C00TS No results 8077 JY8QFUQ01C14RP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8078 JY8QFUQ01CCMOO unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8079 JY8QFUQ01AEVNR No results 8080 JY8QFUQ01BDZEL productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.16.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttGcagctcccattggatgagctgggtccgccagactccagggaagggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8081 JY8QFUQ01CLMHR productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8082 JY8QFUQ01BYA3F productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggGggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8083 JY8QFUQ01A49FA No results 8084 JY8QFUQ01ANH7N unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.16.38.11] CAKN*GVGDG##WYFDFW out-of-frame + stop codons in CDR2-IMGT at codon 57 of V-REGION: 'ACT' (3 nucleotides at position 83 to 85 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) cctctggattcgactttagcggctttgccatgagctgggtccgccaggcccagggaaggggctggagtgggtctcaactattACTaatggtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaattagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8085 JY8QFUQ01BHWWB unknown (see comment) Homsap IGHV4-59*04 F, or Homsap IGHV4-59*08 F (see comment) 259 57.75 123/213 nt 57.28 122/213 nt 8 6 X 8.6.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (57,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtgggacactacctacaactcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8086 JY8QFUQ01A7PBA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8087 JY8QFUQ01DORI9 No results 8088 JY8QFUQ01CFSIW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8089 JY8QFUQ01CMFB0 productive Homsap IGHV3-30*10 F (see comment) 724 81.94 177/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8090 JY8QFUQ01CSDLR No results 8091 JY8QFUQ01B5PCZ productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8092 JY8QFUQ01BD41F No results 8093 JY8QFUQ01A026U unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8094 JY8QFUQ01BSEQP productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8095 JY8QFUQ01AXXBY productive Homsap IGHV3-48*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8096 JY8QFUQ01DBCCE unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 120 53.9 76/141 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8097 JY8QFUQ01CLXOH productive Homsap IGHV3-11*01 F 968 94.04 205/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDPHRGDGCTYDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgactaccacatgggctggatccgccaggctccagggaaggggctggagtgcgtttcatacattagcactagtggtcgtgacatatacaacgcagactctgtgaagggccgattcaccatctccagggacaacgcccagaagtcactgtatctgcaaatgaacagcctgagagccgaggacacagccgtgtatttctgtgcgagggatccccatcgtggagatggctgcacttacgactcctggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8098 JY8QFUQ01CYT4N No results 8099 JY8QFUQ01A98NE productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.16.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctccatgaggaattattactggagctggatccggcagtccccaggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8100 JY8QFUQ01BH6G8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.16.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccacctccgccatggcctgggtccgccaggtccagggaaggggctggagtgggtctcaactattagacctagtagtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8101 JY8QFUQ01BIPQI No results 8102 JY8QFUQ01B4JXT productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8103 JY8QFUQ01BP0Z3 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8104 JY8QFUQ01AN3IA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8105 JY8QFUQ01C9NOK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8106 JY8QFUQ01CBRI8 No results 8107 JY8QFUQ01CRA87 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8108 JY8QFUQ01C36VJ No results 8109 JY8QFUQ01CFINT productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8110 JY8QFUQ01AEIRN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - gtctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8111 JY8QFUQ01A5KVX productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctcgtgcctccatcaatactttttacCtggagctggatccggcagcccccagggaagggactggagtggattggatatatctatgatagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8112 JY8QFUQ01CMFKW productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8113 JY8QFUQ01AN3MM productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1045 95.61 218/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggc 8114 JY8QFUQ01BBS4B No results 8115 JY8QFUQ01AJC34 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcagcttcagtacctataacatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8116 JY8QFUQ01BZLI4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8117 JY8QFUQ01DCVP6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatTggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8118 JY8QFUQ01C8M0C No results 8119 JY8QFUQ01A7R1F No results 8120 JY8QFUQ01C9FNF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8121 JY8QFUQ01C8IS7 No results 8122 JY8QFUQ01CTJ74 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 7 8 10 7.8.10 [2.17.38.11] CAKDFTYAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) gcgtctggattcacgttcagtagtatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 8123 JY8QFUQ01AYQPD productive Homsap IGHV3-7*01 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [0.17.38.11] CSRHGGYTKLYNQNVYLDYW in-frame - ctggattcacatttagcaacttttggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaaaataaacccagtcggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgaaactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8124 JY8QFUQ01CXEFI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - agcctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8125 JY8QFUQ01B3XB9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 935 93.02 200/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggatgggtcAGtctggtataatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8126 JY8QFUQ01BYTOD productive (see comment) Homsap IGHV4-61*02 F 978 94.09 207/220 nt 93.18 205/220 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD5-18*01 F 3 10 7 18 10.7.18 [1.16.38.11] CARVRARSNSHPGHSWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagcagtagGttactactcgacctggctccggcagcccgcggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8127 JY8QFUQ01BM7EF unproductive Homsap IGHV3-11*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 147 to 147 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccaggGgacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8128 JY8QFUQ01A9PRA No results 8129 JY8QFUQ01AD5TZ No results 8130 JY8QFUQ01B0D43 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 840 90.24 185/205 nt 89.27 183/205 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift) ctctggtgactcccacttctggagctggatccggcagcccccgggaaagggcctggagtggattggttatgtctataacagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 8131 JY8QFUQ01BWEM0 No results 8132 JY8QFUQ01DITVH unknown (see comment) Homsap IGHV1-2*02 F 487 86.72 111/128 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg 8133 JY8QFUQ01B2KZQ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 956 92.76 205/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 7 10 10 7.10.10 [1.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgtctggtccagggcttcttccccca 8134 JY8QFUQ01DDWWU No results 8135 JY8QFUQ01B2DWQ No results 8136 JY8QFUQ01CI2X3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 956 92.76 205/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8137 JY8QFUQ01C3YTB No results 8138 JY8QFUQ01B84QO productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); ctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtgGgactctgtgaagggccgattcaccatctcCcagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8139 JY8QFUQ01AJOT0 No results 8140 JY8QFUQ01C8EAO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'T' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattTacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8141 JY8QFUQ01AWIKP productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8142 JY8QFUQ01AJ1AE unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 115 53.57 75/140 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8143 JY8QFUQ01DW6MJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttagcagccatatgatgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8144 JY8QFUQ01C28M8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 16 8.7.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaagggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctncctggtccagggcttcttccccca 8145 JY8QFUQ01BO8TT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8146 JY8QFUQ01A3V06 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRRGLNYYSFMDVW# out-of-frame + ctctggatacagcttcgccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcgatcctagtgactctgataccagatatagcccgtccttccaaggccaagtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgcaggcctcggacaccgccacgtattactgtgcgagacggcggggccttaactactactcctttatggacgtctgggggccaagggacccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8147 JY8QFUQ01BD99G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8148 JY8QFUQ01A4X8T productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8149 JY8QFUQ01BDE5S productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 827 87.44 188/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccgggggcacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8150 JY8QFUQ01BLEDM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [2.17.38.11] CVRGGVSGAFRWGFDYW in-frame - gcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgcttcaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8151 JY8QFUQ01C9L0R unproductive (see comment) Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 X 8.8.X [1.17.38.11] CARGAPIL** (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatattactgtgcgagaggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 8152 JY8QFUQ01B8RK3 No results 8153 JY8QFUQ01DKJ92 productive (see comment) Homsap IGHV3-48*02 F (see comment) 739 81.74 179/219 nt 81.28 178/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8154 JY8QFUQ01BZL35 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact 8155 JY8QFUQ01B7ZVC No results 8156 JY8QFUQ01C53V7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); ctggattcaccttcagGtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8157 JY8QFUQ01CGH13 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8158 JY8QFUQ01A3QW2 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8159 JY8QFUQ01DVPP5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8160 JY8QFUQ01DF6Z2 No results 8161 JY8QFUQ01BTJ17 No results 8162 JY8QFUQ01CZGL8 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8163 JY8QFUQ01BWJDF productive (see comment) Homsap IGHV4-34*03 F, or Homsap IGHV4-34*10 F 862 89.62 190/212 nt 89.15 189/212 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.37.11] CVRNYYDFSGYFNWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacaatccgtccctcaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8164 JY8QFUQ01BHH3Z No results 8165 JY8QFUQ01DCQJH No results 8166 JY8QFUQ01BB5QD productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) gcctcctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8167 JY8QFUQ01BL843 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.38.11] CAKERDNNVLPVDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgaggggccggttcaccgtctccagagacaatTtccaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca 8168 JY8QFUQ01DG8N5 No results 8169 JY8QFUQ01BCDHW No results 8170 JY8QFUQ01AS38N productive (see comment) Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 555 71.62 164/229 nt 71.18 163/229 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [6.17.37.11] CARERDKSGGGAGDFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (71,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 226 in the user submitted sequence), (cause frameshift) tctccagtggcattgttaatggcgaaggttttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctagagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctggagttacagtctgtgaccgccgcagacacggccttatattttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8171 JY8QFUQ01B4U0H No results 8172 JY8QFUQ01CEQAI unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW# out-of-frame + stop codons ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggcccaatgggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8173 JY8QFUQ01B5FJ1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARGHSYYVSSGPDYW in-frame - agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8174 JY8QFUQ01BR5DD productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccggaccagccccaaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccga 8175 JY8QFUQ01CH7UC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8176 JY8QFUQ01BM1BY No results 8177 JY8QFUQ01B2YNB productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8178 JY8QFUQ01A0Z8P unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 89 51.88 69/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8179 JY8QFUQ01CWUWJ productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8180 JY8QFUQ01CTCJT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 8181 JY8QFUQ01APX9E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8182 JY8QFUQ01AOCQ8 No results 8183 JY8QFUQ01A9GRS productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gtctctggcgactccatcagtggtcacCtactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8184 JY8QFUQ01COKT6 unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGF*LDG#YW out-of-frame + stop codons ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttaactcgacgggctactggggccagggaaccctggtcaccgtctcctctgcatccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 8185 JY8QFUQ01CKTYZ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatagcggctcgtccgactacactagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8186 JY8QFUQ01B75LO No results 8187 JY8QFUQ01DBQSW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGVRGVGAYYIYYF#DLW out-of-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttcgacttatggggccagggaaccctggtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8188 JY8QFUQ01DO1TK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8189 JY8QFUQ01DOK8Y productive Homsap IGHV4-61*02 F (see comment) 596 74.66 165/221 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARECSNSKVGPRALDSWG in-frame + Low V-REGION identity (74,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagcccgccgggaagggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctatatttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattcctgggggccccggggaagtctggtcaccgtatcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8190 JY8QFUQ01CQYQ6 No results 8191 JY8QFUQ01C4ME7 No results 8192 JY8QFUQ01C9SPS No results 8193 JY8QFUQ01CBYYT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8194 JY8QFUQ01CQXW9 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame - stop codons in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); ctctgggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatgGgtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8195 JY8QFUQ01C404O No results 8196 JY8QFUQ01DKGVY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARFGPLTRPDYW in-frame - tctggatcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8197 JY8QFUQ01BTYDV productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1072 99.09 217/219 nt 97.72 214/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 43 to 44 in the user submitted sequence), (cause frameshift); gcctctggattcaccGttcagtagGctatagcatgaactgggGTccggccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 8198 JY8QFUQ01CGQ8K No results 8199 JY8QFUQ01B9EGZ productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8200 JY8QFUQ01CAZ62 No results 8201 JY8QFUQ01AN1PQ unknown (see comment) Homsap IGHV3-11*01 F (see comment) 633 77.1 165/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AN1PQ ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8202 JY8QFUQ01C2YS7 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 904 89.33 201/225 nt 88.0 198/225 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 12 8.10.12 [2.17.38.11] CTITVRPDDYHDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); gtctctggagtcactttcactaacgtgtggatgagttgggtccggcagGgctccagggaaAGggggccggagtgggttggccgtattaaaagggagactgacggggggacaatagactacgctgcacccgtgacagcaagattcaccatgtcaaaagatgattcCaaaaaacacactatatctgcaaatgaacaacctgaaaatggaggacacagccgtgtattactgtaccataacagtccgaccggatgattaccatgactactggggccagggaaccctggtgaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8203 JY8QFUQ01B81I7 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact 8204 JY8QFUQ01DASUZ productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8205 JY8QFUQ01A404T No results 8206 JY8QFUQ01C8KNM productive (see comment) Homsap IGHV3-30*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [2.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8207 JY8QFUQ01DJCWQ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcactttcagtga 8208 JY8QFUQ01AHDAJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8209 JY8QFUQ01DW4U2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc 8210 JY8QFUQ01AY67B productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagtaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8211 JY8QFUQ01BAELP unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD2-8*02 F 2 8 7 X 8.7.X [1.17.38.11] CARVVTTTILYWV#YYFDSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); ctatggtgcgtccttcagtgattactcctgggcctggatccgccagTcccccagggaaggggctggagtggattggagagatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgaggcatcatatcaatagacatgtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtatattactgtgcgagagtcgtcacgactacaattttatactgggtcctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8212 JY8QFUQ01C1AVK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.16.38.11] CARGLDPGTNDYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) acctctggattcatcttcagtggctactggatgcactgggtccgccaagtcccagggaagggctgtgtgggtctcacgtgttaatcgcgatggaactaatacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaagactttctatcttcaaatgaacagtctgaaggtcgaggacacggctctatattattgtgcaagaggcctggaccctggcaccaacgactactttgactcctggggccagggaaccctggtcaccgtcgcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactcag 8213 JY8QFUQ01CUVK8 unproductive Homsap IGHV3-48*02 F 881 90.23 194/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [0.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8214 JY8QFUQ01ACQTF unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 270 92.06 58/63 nt 8 X X 8.X.X [1.11.X.X] null + No rearrangement found ctctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaagggctg 8215 JY8QFUQ01BSHY5 No results 8216 JY8QFUQ01CJ3C7 productive Homsap IGHV3-48*01 F 873 89.4 194/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8217 JY8QFUQ01B361P productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8218 JY8QFUQ01A2SA0 productive Homsap IGHV4-4*07 F (see comment) 1021 97.22 210/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 10 7 13 10.7.13 [2.17.38.11] CARDFSNRGWYFDLW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01A2SA0 ; 8 AA in Homsap_IGHV4-4*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctggtgactccatttccagtactagttattactggggctgggtccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8219 JY8QFUQ01DE3MC productive (see comment) Homsap IGHV3-9*01 F 901 90.41 198/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); gcctctggattTaacctttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtAgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8220 JY8QFUQ01A1KJ6 No results 8221 JY8QFUQ01BNCWH unknown (see comment) Homsap IGHV3-48*01 F 968 94.04 205/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctctggtgggtccttcagtggttacttctggaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag 8222 JY8QFUQ01BFH58 No results 8223 JY8QFUQ01CTE1V productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8224 JY8QFUQ01CH1K2 No results 8225 JY8QFUQ01CS6YL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgGaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8226 JY8QFUQ01ADJZC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8227 JY8QFUQ01A48BS No results 8228 JY8QFUQ01BR1M6 No results 8229 JY8QFUQ01AVBV0 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 858 89.25 191/214 nt 88.32 189/214 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.16.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 77 of V-REGION: 'C' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctccatgaggaattattactggagctggatccggcagtccccaggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaCccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8230 JY8QFUQ01BB5SC No results 8231 JY8QFUQ01B3K61 No results 8232 JY8QFUQ01CIAEG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8233 JY8QFUQ01DNHOD unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1010 97.64 207/212 nt 96.7 205/212 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.37.11] CARLGSGG*SWL#YADYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 108 in the user submitted sequence), (cause frameshift) tctggtggctccatcagtCagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaaccctccctcaagagtcgggtcaccatgtcagtggacacgtccaagaaccagttctccctgaagctgagctctctaaccgctgcggacacggccgtgtattactgtgcgagactagggtccggggggtagtcgtggttattacgctgactactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8234 JY8QFUQ01C344R productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 865 88.58 194/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [2.17.38.11] CTRVGTFNWFGPW in-frame - gcctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8235 JY8QFUQ01DNHYA productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSRSPANW in-frame + ctctggattcagttttagtacctattggatgagctgggtccgccaggctccagggaaggggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaattcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8236 JY8QFUQ01BM618 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); aatgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8237 JY8QFUQ01BNLHU productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8238 JY8QFUQ01A9A1W No results 8239 JY8QFUQ01CH781 No results 8240 JY8QFUQ01DL1LT productive (see comment) Homsap IGHV1-3*01 F 956 94.81 201/212 nt 94.34 200/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 7 9 8.7.9 [0.17.38.11] CARWNNDLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8241 JY8QFUQ01CJOBK productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8242 JY8QFUQ01C5M80 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDDGGTH##LDVW out-of-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcacatttcgaagttattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcggctgtaagtggtggtggcggcgccacaacctacgcggactccgtgaagggccggttcaccatctccagagacaatacacagaagatggtgttcctagaaatgagcagcctgagagtcgaagacacagccttatattattgtgcgcgagatgacggggggacacatgactttagatgtctggggccaggggacaatggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8243 JY8QFUQ01DI09E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8244 JY8QFUQ01AE9OW No results 8245 JY8QFUQ01A8G0E productive (see comment) Homsap IGHV3-11*01 F 904 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.37.11] CARRLLSSGWPPHEWGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaagggactggagtgggtctcatatattagcagtactggtggttccatatattacgcagactctgtgaagggccgcttcaccacctccagggacaacaccaaaactcaatgtctctgcaaatgaacagcctgagcgtcgacgacacgggcgtctattattgcgcgagaaggcttctcagtagtggatggccaccccacgagtggggcttctggggccagggagtccaggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 8246 JY8QFUQ01AF3ZS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8247 JY8QFUQ01CRDF7 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8248 JY8QFUQ01CGTZG No results 8249 JY8QFUQ01DHR8T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8250 JY8QFUQ01BX6XO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8251 JY8QFUQ01BWIHJ productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaaaCgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8252 JY8QFUQ01C2NGE productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8253 JY8QFUQ01DSYYV No results 8254 JY8QFUQ01AV27W productive Homsap IGHV3-30*15 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + cctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8255 JY8QFUQ01BGXD7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame - ctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcaaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8256 JY8QFUQ01C82ML No results 8257 JY8QFUQ01CC5OR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8258 JY8QFUQ01B78ZT unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREDGFRQT##FDYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggttccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8259 JY8QFUQ01DIBAK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame + ctctggattcattttcagtaactataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagtcacatatactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8260 JY8QFUQ01BO2N3 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'AG' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift); tggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtAGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8261 JY8QFUQ01B1ZC8 No results 8262 JY8QFUQ01CVLIG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame + ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggacgtggtcgtcgcatgcctggtccagggcttcttccccca 8263 JY8QFUQ01AZFTQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacgggggggactagcacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 8264 JY8QFUQ01BKRE0 productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + tggatacaccttcaccagttactatatgcactgggtccgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8265 JY8QFUQ01AKLI2 No results 8266 JY8QFUQ01AKVGF unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 654 93.88 138/147 nt 93.2 137/147 nt 8 8 X 8.8.X [1.17.13.X] null - No rearrangement found in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 126 in the user submitted sequence), (cause frameshift) cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaaggccgattcaccatctccagaga 8267 JY8QFUQ01CJFIZ productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [2.17.38.11] CARGWAQQAGATFVGWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'GA' (2 nucleotides at position 80 to 81 in the user submitted sequence), (cause frameshift); gtctatggtgggtccttcagtggttacacctggaactggatccgccagcccccagggaaggggctggagtggattggggGAaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8268 JY8QFUQ01DD0HG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaGggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8269 JY8QFUQ01C1K01 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 800 86.05 185/215 nt 85.58 184/215 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.37.11] CVRDSDSSGYARYDSMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) tctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgagggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaaggccatcggtcttccccctggcgccctgctccaggagcacctccgagagcaccagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 8270 JY8QFUQ01CTZLW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.16.38.11] CAKSPLSVAGTRQNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaagggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8271 JY8QFUQ01AZFGT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 768 84.58 181/214 nt 82.71 177/214 nt Homsap IGHJ1*01 F 170 80.77 42/52 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.16.37.11] CARPDGGNGWAAKYFQMW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'AT' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 2 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) ctctgggttctcgtttaatagttatggcatgacatggttccgccaggctccggggaggggctggagtgggtcATgcatctataactggaactgggggtaacgttttctacgcagacttcgtgcagggccggttTcaccatctccagagacaattccgacaatgttgtttctgcaaatgaacagcctgagagttgaggacacggccgtgtattactgtgcgagacctgacggaggcaatggctgggccgcaaagtactttcagatgtggggccagggcacccttctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8272 JY8QFUQ01BWI99 No results 8273 JY8QFUQ01B0K72 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKINNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttcccccag 8274 JY8QFUQ01B48EK unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] CARGVAGP#YFDSW out-of-frame + in FR3-IMGT at codon 103 of V-REGION: 'G' (1 nucleotides at position 217 to 217 in the user submitted sequence), (cause frameshift); ctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattaGctgtgcgaggggcgtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcggaacgtggtcatcgctgcctggtccagggcttcttccccca 8275 JY8QFUQ01C008Z No results 8276 JY8QFUQ01CTBVM No results 8277 JY8QFUQ01CA62S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ6*04 F (see comment) 100 64.29 36/56 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CMNEFGYCSGGG in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagcccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccc 8278 JY8QFUQ01AX4R6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8279 JY8QFUQ01BEYZ9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 2 8 7 9 8.7.9 [1.17.38.11] CARDNYGDYWG in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8280 JY8QFUQ01AEMOQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [0.17.38.11] CAKVVWSLWYFDLW in-frame + tacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8281 JY8QFUQ01CIX1D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8282 JY8QFUQ01CM5UQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 8283 JY8QFUQ01CAD43 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8284 JY8QFUQ01CQ9TR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8285 JY8QFUQ01AKSCK unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 307 73.11 87/119 nt 8 8 X 8.8.X [1.17.6.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01AKSCK ; 7 AA in Homsap_IGHV3-69-1*01), and low V-REGION identity (73,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactacttccccgaaccggtgacggtgtcgtggaactcag 8286 JY8QFUQ01CCYFY productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8287 JY8QFUQ01C2LO1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8288 JY8QFUQ01B7E8G No results 8289 JY8QFUQ01B0DXX productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgtctggtccagggcttcttccccca 8290 JY8QFUQ01BK1TY productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8291 JY8QFUQ01B1Z8K No results 8292 JY8QFUQ01BJ6IJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARDSGMFCNSGSCYVYYGPDLW in-frame + ctctggattcttcttcagcagttttggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggcagtcacatcatatgatggaggtaataaattttatggagactcagcgaagggccgattcactatctccagagacaattccaaaaacacactgtatctgcaaatgaacagactgacaactgaggacacggctacttattactgtgcgagagattcggggatgttttgtaacagtggtagttgctacgtctattacggcccggacctctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8293 JY8QFUQ01AWUSJ productive (see comment) Homsap IGHV3-30*15 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.37.11] CARNELPWDTREYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift) ctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc 8294 JY8QFUQ01AJDTG productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8295 JY8QFUQ01DEH5B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - gtctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8296 JY8QFUQ01BVDDW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 17 8.8.17 [1.17.38.11] CANQWDSMVRGLITAPDYW in-frame - cctctggattcacctttaacacctatgccatgacctgggtccgtcagactccagggacggggctggaatgggtctcacttattagtggtagtggtgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacactatatttgcagatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaatcagtgggatagtatggttcggggacttattaccgctcccgactactggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8297 JY8QFUQ01BN1G9 productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFNNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttaacaactggggccagggaaccctggtcactgtgtcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8298 JY8QFUQ01BYSMX No results 8299 JY8QFUQ01BZXBW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacgaccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8300 JY8QFUQ01BTACU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CATDGVGSTVKLMVMGPFDFR in-frame + ctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccagggaaggggttggagtgggtctcatctattagtactagtgggactaactcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagcaagcgctttatctgcagatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8301 JY8QFUQ01CS6JS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8302 JY8QFUQ01CU8I3 productive Homsap IGHV3-9*01 F 1054 98.17 215/219 nt Homsap IGHJ6*02 F 292 96.77 60/62 nt Homsap IGHD5-18*01 F 1 8 8 18 8.8.18 [2.17.38.11] CAKAGTARDTYHYYYGMDVW in-frame - gcctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtgataggataggatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatggacagtctgagagctgaggacacggccttgtattactgtgcaaaagcaggtacagccagagatacttaccactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8303 JY8QFUQ01C3TUN productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccCaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 8304 JY8QFUQ01A1DVA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8305 JY8QFUQ01BE51J unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagcccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 8306 JY8QFUQ01A8H4Q No results 8307 JY8QFUQ01BG431 No results 8308 JY8QFUQ01CKCKN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD5-18*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKNGPRGYSYGYYYYAMDVW in-frame + ctctggactcacctttaccacctttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgctagtggtggtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaagagcctgagagccgaggacacggccgtatattactgtgcgaaaaacggtccccgtggatacagctatggctactactactacgctatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8309 JY8QFUQ01DAMYQ No results 8310 JY8QFUQ01C5XO0 No results 8311 JY8QFUQ01CXU11 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 678 79.44 170/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CXU11 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactca 8312 JY8QFUQ01ASCDY No results 8313 JY8QFUQ01C6FF8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8314 JY8QFUQ01DP4MG productive (see comment) Homsap IGHV4-4*07 F (see comment) 566 73.95 159/215 nt 72.56 156/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (73,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttcggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgcaaaactctaActacaaTcccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8315 JY8QFUQ01C8UR6 No results 8316 JY8QFUQ01DW754 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaaGgaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8317 JY8QFUQ01CYT72 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 8318 JY8QFUQ01A2BAW productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8319 JY8QFUQ01BOWCG unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 603 75.12 163/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8320 JY8QFUQ01CRV27 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 83.87 182/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtaatggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8321 JY8QFUQ01DPW7U productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8322 JY8QFUQ01AJTMK productive (see comment) Homsap IGHV3-11*01 F 535 92.06 116/126 nt 91.27 115/126 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 X 14 8.X.14 [1.5.27.11] CARDDSCSGGSCYEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 92 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) cctctggattcagtttcagtgactactacatgagttggatccgccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8323 JY8QFUQ01AXQK9 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 8324 JY8QFUQ01CVK8G unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 131 52.11 99/190 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8325 JY8QFUQ01A5E27 productive (see comment) Homsap IGHV3-30*12 F, or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 181 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 8 7 13 8.7.13 [1.17.38.11] CASSRDGYNHGXRYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 3 nucleotides (from position 101 in the user submitted sequence), (do not cause frameshift) gtctggattcaccctcagctcctatggcatgcactgggtccgccgggctccaggcaaggggctagagtgggtggcgaatatgtttcatgatggaggctcttactatggaccctccgtgaggggccgattcaccatctccagagacaattcgaagaacacgctatttctacaaatgaacagcctgagagccgaggacacggctctatattactgtgcgagtagtagagatggctacaatcacggcttnagatactggggccagggaaccctggtcaccgtctcctctgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8326 JY8QFUQ01AV6V8 No results 8327 JY8QFUQ01C6R5U unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8328 JY8QFUQ01DBYM0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CGKQLGPIKG#DYW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaaccattggatgaactgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattggggcccataaaggggctgactactggggccaggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 8329 JY8QFUQ01C7I08 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 805 86.11 186/216 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDSW# out-of-frame + tctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggtcctgggaacccctggtcgccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 8330 JY8QFUQ01C6F0T productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8331 JY8QFUQ01ANO1M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8332 JY8QFUQ01B36PI productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - cctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8333 JY8QFUQ01DRR7K unproductive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQW# out-of-frame + stop codons in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtgggggcccagggaaccctagtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag 8334 JY8QFUQ01A3H9O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGIVGDTFFDYW in-frame + tctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgagatcccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8335 JY8QFUQ01AQY4E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8336 JY8QFUQ01AJPR3 No results 8337 JY8QFUQ01A60HF productive Homsap IGHV3-7*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [2.17.38.11] CAREQSSRGYPLDYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatacccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8338 JY8QFUQ01CTQ1N productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 781 84.98 181/213 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGEECRSGSCYSVWFDPW in-frame + Low V-REGION identity (84,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtgggtccttaagtgactcctactgggcctggatccgccagcccccagggaagggcctggagtacattggggagatcagtcatgatggtagaaccatgttcaattggtccctcaagagtcgactcaccatctcagtagacacgtccaagaatcaattctccctgagattgacctctgtgaccgccgcggacacggctgtttattactgcgcgagaggcgaggaatgtcggagtggaagttgctactccgtttggttcgacccctggggccagggagcccaagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8339 JY8QFUQ01A0X8W productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDSRHSASGSYSDYW in-frame - gcgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8340 JY8QFUQ01CGIRF No results 8341 JY8QFUQ01B9VGM No results 8342 JY8QFUQ01ADMI2 No results 8343 JY8QFUQ01CT6QL productive Homsap IGHV3-48*02 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARVENYSDSGGSFDYW in-frame - gcctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaattactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcattgcctgcctggtccagggcttcttccccca 8344 JY8QFUQ01BHMCF unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 544 76.6 144/188 nt 8 8 X 8.8.X [1.17.28.X] null - No rearrangement found Low V-REGION identity (76,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttgatgattttgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaggatagtctatgcggactctgtgaagggccgattcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8345 JY8QFUQ01CUABV No results 8346 JY8QFUQ01DNRFJ No results 8347 JY8QFUQ01C2F53 productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 8348 JY8QFUQ01AY6HZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8349 JY8QFUQ01DWXJO productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 926 92.56 199/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatcccctaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8350 JY8QFUQ01C1PQ2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8351 JY8QFUQ01ARC40 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8352 JY8QFUQ01DQFTR unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAQRSPER*LHIRRI*SV# out-of-frame - stop codons Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgcccaaagatcgcctgaacggtgactacacattcggcgcatttgatctgtgggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 8353 JY8QFUQ01DBICC productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8354 JY8QFUQ01CAXM3 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - ctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8355 JY8QFUQ01CFMFT productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8356 JY8QFUQ01AU0NX productive Homsap IGHV4-61*02 F (see comment) 645 77.27 170/220 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 10 7 13 10.7.13 [1.17.38.11] CATHSNGGARALDSW in-frame + Low V-REGION identity (77,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ctctggtggccccgtcaacactgctggtctcttctggagctgggtccggcagcccgccgggaaacgacttgagtggatcggacatgtttctggtggaggggacaccacctacaatccctccctcgagagtcgggtcaccatgtcgttggattccctcaaaaacgagatctccctgacgttgacttccgtgaccgccgcagacacggccgtctactattgtgccactcattccaacggcggagcgagagcacttgactcctggggccagggggccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8357 JY8QFUQ01C7FZL unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 99 49.31 107/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctcaggattcatgttcaataactattggatgcattgggtccgccaagctccaggggagggcttggtgtgggtcgcacgtatcagcagtgatgggaacccgagtcaccgtctcttcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg 8358 JY8QFUQ01CR090 productive Homsap IGHV3-48*01 F 814 86.57 187/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8359 JY8QFUQ01DQQAC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8360 JY8QFUQ01CZDBR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDPGNYWGYYYDS## out-of-frame + ctctggattcacctttagcagttatgccatgagctgggtccgccagactccagggaaggggctggagtggatctcagaaattactggtgatggcgataacatatactacgcagactccgtgaagggccgtttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatccggggaactattgggggtactactatgactcttgggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 8361 JY8QFUQ01CLKP9 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 34 of V-REGION: 'ACC' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift); gtctttggtgactctctgagtACCagtagcagtttctactggggctgggtccgccaggccccagggaagggactggagtgggttgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccaaaaccaggtctccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8362 JY8QFUQ01C4BMN unproductive Homsap IGHV4-61*03 F 152 66.25 53/80 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 3 X X X X.X.X [X.X.26.11] CATVRHLGERIFDF# out-of-frame + tctctggggccaccatgagtagtttctactggagctggctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctgggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 8363 JY8QFUQ01C0WTC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8364 JY8QFUQ01CO7OU No results 8365 JY8QFUQ01BFB0Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 845 88.37 190/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 7 15 8.7.15 [1.17.38.11] CAKVYTGAWGDPNFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtactttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8366 JY8QFUQ01AKV8X unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 2 8 8 X 8.8.X [1.16.38.11] CANASPRITGN#YFYYYGMDVW out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaagggctggagtgggtctcagccattagtggtantggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactgggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8367 JY8QFUQ01CVFKN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggGtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8368 JY8QFUQ01CX9OH No results 8369 JY8QFUQ01DMWUQ No results 8370 JY8QFUQ01CQ80T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8371 JY8QFUQ01B3J5C productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8372 JY8QFUQ01BQ9G8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 8 8 8.8.8 [1.17.38.11] CAVNWNLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcggctatgccatgagctgggtccgccaggctccagggaaggggctggactgggtctcatctattagttataatggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctccaaatgaacagcctgagagccgaggacacggccgtatattactgtgctgtgaactggaaccttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8373 JY8QFUQ01A31S4 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8374 JY8QFUQ01AUZHT unproductive (see comment) Homsap IGHV3-66*02 F 924 93.36 197/211 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [0.17.38.11] CVGDRQRDNYFAYW in-frame - stop codons tggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggctgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8375 JY8QFUQ01CQ4WI productive (see comment) Homsap IGHV1-3*01 F 849 88.79 190/214 nt 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggGggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8376 JY8QFUQ01CP0UW No results 8377 JY8QFUQ01AK05F unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 281 65.54 97/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (65,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8378 JY8QFUQ01B23WP productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8379 JY8QFUQ01CZXHW unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8380 JY8QFUQ01BFEGU productive (see comment) Homsap IGHV3-9*01 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 7 8 22 7.8.22 [1.17.37.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) tctggattcactttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8381 JY8QFUQ01DHSAM No results 8382 JY8QFUQ01AIXJL productive (see comment) Homsap IGHV3-23*05 F 791 87.38 180/206 nt 86.41 178/206 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [X.16.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ttcacctttggcacctctgacatggcctgggtccgccaggttccaggggagggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8383 JY8QFUQ01CNCBL productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1034 98.14 211/215 nt 97.67 210/215 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctgggttcaccgtcagtagcGaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8384 JY8QFUQ01BN1A6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8385 JY8QFUQ01BJLQG productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 919 91.32 200/219 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CARDDFYSSGNYGGFGMDVW in-frame - gcctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaggggctagattgggtggcatttatatcatatgatggaagtaatgagttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagcccgaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8386 JY8QFUQ01CC9VV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8387 JY8QFUQ01DP27V No results 8388 JY8QFUQ01BRM16 No results 8389 JY8QFUQ01C0NSG unproductive (see comment) Homsap IGHV3-21*04 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggattcgccttcagtacatatatcatgaattgggtccgctaggctccagggaaggggctggagtgggtctcatccattagAttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8390 JY8QFUQ01DRBJQ No results 8391 JY8QFUQ01CN5XI productive (see comment) Homsap IGHV3-9*01 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.16.38.11] CARGIAVAASHESTFDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 42 of V-REGION: 2 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) ctctggattcacctttgatgattttgccatgcactggtcggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaggatagtctatgcggactctgtgaagggccgattcaccatctccagagacaacgcccagaactccctgtatctgcaaatgaacagtctgggtactgaggacacggccttgtattactgtgcaaggggtatagcagtggctgcctcccacgagtcgacttttgactactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8392 JY8QFUQ01AXL5M unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 896 89.91 196/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8393 JY8QFUQ01BK7CO unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 766 83.56 183/219 nt 82.19 180/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - stop codons Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'AGCTG' (5 nucleotides at position 64 to 68 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'AGTAAC' (6 nucleotides at position 94 to 99 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccgggggaagggAGCTGgtggctagggtctcactaatcattaAGTAACtggatggtaactgaaatagAccacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggtaacgtggtcatcgcctgcctggtccagggcttcttccccca 8394 JY8QFUQ01DS112 No results 8395 JY8QFUQ01CES1G No results 8396 JY8QFUQ01B6CNR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8397 JY8QFUQ01BBC0J unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8398 JY8QFUQ01CJIFK unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 8399 JY8QFUQ01BES39 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgatcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8400 JY8QFUQ01A42MA unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 8401 JY8QFUQ01CN631 No results 8402 JY8QFUQ01DHS87 No results 8403 JY8QFUQ01AZOSQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) aggcctctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8404 JY8QFUQ01COAJR No results 8405 JY8QFUQ01BKUNY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - tctctaatgggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8406 JY8QFUQ01B0V5N No results 8407 JY8QFUQ01A8N9K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 8408 JY8QFUQ01DGZ15 productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8409 JY8QFUQ01BGUJA unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRSGQAVGY## out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggctgtcgtggaac 8410 JY8QFUQ01CG2UM productive Homsap IGHV3-7*03 F 845 88.37 190/215 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [0.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + ctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8411 JY8QFUQ01DUYGA productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccacaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8412 JY8QFUQ01AKPPR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVKDWGPNRQMWFGES#SG out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 62 of V-REGION: 'GCTGTTGCC' (9 nucleotides at position 92 to 100 in the user submitted sequence), (do not cause frameshift); ctctggattcacgttcagcagctatgccatgacctgggtccgccagactccagggaaggggctggagtgggtctcaactattcatggcggtGCTGTTGCCggtggcaccacagactacgcggtctccgcccagggtcgattcaccatctccagagacaattccaagagcacactgtatttgcaaatgagcgacctgagacccgaggacacggccctctatttctgtgtgaaagactggggccccaatcggcagatgtggttcggggagagtctctggggcccagggaactctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8413 JY8QFUQ01A4ER3 No results 8414 JY8QFUQ01AZS6M unproductive (see comment) Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 8415 JY8QFUQ01DH35L productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8416 JY8QFUQ01B3HI3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccaatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8417 JY8QFUQ01BNZ0M productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8418 JY8QFUQ01AS4EZ productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 609 96.92 126/130 nt 96.15 125/130 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 X 9 8.X.9 [1.3.31.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) gtctggattcaccttcaggagctattggatgagctggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8419 JY8QFUQ01DFVGJ productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 923 86.53 212/245 nt 85.71 210/245 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 20 of V-REGION: 'C' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 28 of V-REGION: 'AT' (2 nucleotides at position 34 to 35 in the user submitted sequence), (cause frameshift); agaccctcCaccctgacctgcgacttctctgggATtcctcactcagcaccaatggaatgggtgtgggttggatccgccagaccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8420 JY8QFUQ01BSEGS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.17.38.11] CAKQKHSYGYYFDQW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcacGctttaaaacacatgccatgagctgggtccgccaggctccaggaaAaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8421 JY8QFUQ01CDYW8 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8422 JY8QFUQ01CSIQ6 productive (see comment) Homsap IGHV3-11*01 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD2-2*01 F 3 8 7 20 8.7.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccagggggcacacggtcaccgtctcctagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8423 JY8QFUQ01CR487 productive Homsap IGHV4-61*01 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [2.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - tgtctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8424 JY8QFUQ01DH323 productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacaacctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8425 JY8QFUQ01AT3GM productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8426 JY8QFUQ01AO8X8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 720 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CAKVKGYGGNWFQPHFDRW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattctccttcgaggggtctgtcgtgacctgggtccgacaggctccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaattccaaggacacggtctatctgcagatgaacggcctgagagtcgaagactcggcccgttattattgtgcgaaagtgaagggctacggcggcaattggttccagcctcactttgaccgctggggccagggcaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8427 JY8QFUQ01AUUMM No results 8428 JY8QFUQ01DCS74 productive Homsap IGHV3-48*01 F 810 85.78 187/218 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtntgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcgggctcttccccctggcacctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaggactacttcccccgaaccggtgacggtgtcgtggaactcag 8429 JY8QFUQ01BD3EO productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 677 92.41 146/158 nt 91.14 144/158 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 18 10.7.18 [1.17.17.11] CARLLRVYDWYSQRGYFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 71 of V-REGION: 62 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ctccgatggctccatcagcactagtaattactactGggggctgggtccgccagcccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaaggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8430 JY8QFUQ01C3Z9T No results 8431 JY8QFUQ01BV5JV No results 8432 JY8QFUQ01CWNIA productive (see comment) Homsap IGHV3-66*02 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'CA' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggCAaaggggctggagtgggtctcagttatttataccgGggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8433 JY8QFUQ01CKSAU productive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 878 89.45 195/218 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame + tctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8434 JY8QFUQ01CLD43 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8435 JY8QFUQ01C4LCW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKRWRASNGHFDYW in-frame - ctctggattcacctttagcagcttttccatggggtgggtccgccaggctccagggcggggactggagtgggtctcagccattgacggtcttactggtggtacatattacgcggactccgtgaggggccgattcaccatctccagagacgattccaagaacacactgtatctgcaaatgaatagcctgagagccgaggacacagccatatatcactgtgcgaagcggtggcgtgcttccaatggccactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8436 JY8QFUQ01AWG4X unproductive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 975 95.33 204/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [0.17.38.11] CVRGNAVVAASDD## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggaggcaccttcagcagtcatgctatcagctgggtgcgacaggcccctggacaagggcttgagtggatgggcgggatcatccctagttttggtacaccaaactacgcacagaagttccagggcagagtcacgatgaccgcggacgaatccacgagcacagcctacatggagctgagcagcctcagatctgaagacacggccgtgtattattgtgtgagaggtaacgcggtggtagctgccagcgacgactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8437 JY8QFUQ01BVWRE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8438 JY8QFUQ01C9UFU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8439 JY8QFUQ01BE1A6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8440 JY8QFUQ01AUWN1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-7*01 F 3 8 8 19 8.8.19 [2.17.38.11] CAKVFQVPGEHHFYYFGMNVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcatgtttaggaactatgccatgagttgggtccgccaggctccagggaaggGggctggagtgggtctcaactattagcaataatggaagccacacatactacgcagactccgtcaagggccggttcaccatctccagagacaattccaagaacacggtgtatatgcagatgaacaggctgagagtcgaggagacggccctgtactactgtgcgaaagtcttccaggtgcctggcgagcaccacttctactacttcggaatgaatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8441 JY8QFUQ01BJJ53 productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8442 JY8QFUQ01C8JQA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 962 92.41 207/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaaggcttcttccccc 8443 JY8QFUQ01DRH2R productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccaCtttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8444 JY8QFUQ01DK55H No results 8445 JY8QFUQ01BZ3H3 No results 8446 JY8QFUQ01DOTLO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 836 89.81 185/206 nt 88.35 182/206 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactcccacttctggagctggatccggcagcccccgggaaaagggctggagtggattggttatgtctataaAcagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8447 JY8QFUQ01AVINK unproductive Homsap IGHV3-48*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [1.17.38.11] CARESWWSGFM#WYDPW out-of-frame - in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcaCtttactatgcagactctgtgatgggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggctttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8448 JY8QFUQ01CKH2H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttacCtggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgaaactcag 8449 JY8QFUQ01AFES7 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 917 90.18 202/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDRRGLSIPPQFDFW in-frame - cctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggccgtataaaaaacaaagctatgggtgagacaacagacttcgctgcacccgtgagaggcagattcagtatctcaagagatgattcaaaaaatacactgtatctgcacatgagtggcctgaaaaccgaggacacagccgtctattattgtaccacagatcggcggggtttgtctataccacctcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8450 JY8QFUQ01BWRCS No results 8451 JY8QFUQ01B4AEC productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 84.55 186/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggaTttgggcgcttctacagtcgtCgggggtgtcgactacaaccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8452 JY8QFUQ01DI5YM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + ttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtgggggggtccagggagccctggtcaccgtctcctcaggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8453 JY8QFUQ01C9O87 productive Homsap IGHV3-64*02 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRPMAGFHGILYDNW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 8454 JY8QFUQ01CO27Z productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1008 94.25 213/226 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame - ctccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8455 JY8QFUQ01AHMPT unproductive Homsap IGHV4-34*10 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.16.38.11] CARNTNYGGNSGDYFDY## out-of-frame - in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tgtctggtgagtccttcactaattactactggagctgGgatccgccagtcccccaggaAAagggtctggagtggcttggggagtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccacgggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8456 JY8QFUQ01A5MS2 productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8457 JY8QFUQ01C4BD8 productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatGggggcgtatctataccagtgggatcaccaactacaaccCcctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 8458 JY8QFUQ01AGDEN No results 8459 JY8QFUQ01A5MZO productive Homsap IGHV3-72*01 F 867 87.89 196/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGYDYW in-frame + ctctggattcatcttcagtgaccactatatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagagttgcatctaacacttacgccacagaatacgccgcgtctttcagaggcagattcgtcatctcaagagacaactcaaggaaatcattgtttctccaaatgaacagcctgagaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctacgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8460 JY8QFUQ01BBON6 unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 8461 JY8QFUQ01C8MB7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8462 JY8QFUQ01AFCLH productive Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8463 JY8QFUQ01B6W3L unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 125 56.52 65/115 nt 8 10 X 8.10.X [1.17.2.X] null + No rearrangement found ctctggattcagctttagttactattggatgagctgggtccgccaggctcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8464 JY8QFUQ01AQJU6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8465 JY8QFUQ01DDXSG productive Homsap IGHV3-30*05 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F or Homsap IGHV3-30*13 F (see comment) 747 82.95 180/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-13*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAREADGQDLTTHLNWFDPW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgcactgggtccgcctgtctccaggcaggggcctagagtgggtggcaggaatctcacacgatggcagtcagacagactacgcagcctccgtgaagggccggttcatcatttctagagacaattccaaagacacagtgtttctggaaatgaaaagcctgggcggagaagacacggctgtttactattgtgcgagagaagcagatgggcaagacctgacgacccacttgaactggttcgacccctggggccagggaatccaggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8466 JY8QFUQ01AXYTN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.16.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) agcctctggattcacctttaccacctccgccatggcctggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8467 JY8QFUQ01A3FZJ productive Homsap IGHV3-21*04 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8468 JY8QFUQ01DEG6Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggactggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggcccatcggtctccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8469 JY8QFUQ01DNS6I unknown (see comment) Homsap IGHV3-7*02 F 972 94.47 205/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8470 JY8QFUQ01DR3V5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 952 94.37 201/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtttggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8471 JY8QFUQ01BHB74 No results 8472 JY8QFUQ01A8IW5 No results 8473 JY8QFUQ01AVE0F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8474 JY8QFUQ01CXU7L productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); cttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattaCcttatcctgatggtactacatattatggagaccccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8475 JY8QFUQ01DU4E2 unproductive (see comment) Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggcagccctggtccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8476 JY8QFUQ01C8ZZL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8477 JY8QFUQ01AZAYV productive Homsap IGHV3-11*01 F (see comment) 789 84.55 186/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARYRGSYYDYGGVDVW in-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release aacctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8478 JY8QFUQ01CDB52 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8479 JY8QFUQ01CTPGJ productive Homsap IGHV3-11*01 F 848 87.33 193/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [2.17.38.11] CVREVTGVWDWFDPW in-frame - cagcctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8480 JY8QFUQ01BYHGN productive (see comment) Homsap IGHV4-4*07 F 863 89.3 192/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [2.17.37.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 112 to 113 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) gtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagcCccccactacaaACcccttccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccattttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8481 JY8QFUQ01B97JU productive Homsap IGHV3-30*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + cctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcgcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 8482 JY8QFUQ01CJKNZ No results 8483 JY8QFUQ01BQERC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 8 8.8.8 [1.17.38.11] CAKRYSLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctctggattcacctttaagaactatgccttaaAactgggtccgccaggctccagggaaggggctgaagtgggtctccggaatcagtgctactggtgaaagcacacactacgcagactccgtaattggccggttcaccatctccagagacgattccaagaatacgttatatctgcaaatgaacagcctgagagccgaggacacggccgtatatttctgtgcgaaacgatattctcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8484 JY8QFUQ01BT8WY productive (see comment) Homsap IGHV3-11*01 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRSYKLRGGLYYFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); ctctggattcatcttcgatgactacttcatgacctggatccgccaggctccaTgggaaggggctggagtggatttctcacattgatggtagcggttctaccaggcactacgcagactctgtgaggggccgcttcaccatctccagggacaacgccaagaactccctttttctgcatatgaacagcctcagagtcgaggacacggccgtgttttactgtgtgagatcctacaaacttaggggaggtctttactactttgactcctggggccagggaagcctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8485 JY8QFUQ01BXALZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame + tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8486 JY8QFUQ01CLJ0E unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARAYSGPGPYYFD#IG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattgggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccag 8487 JY8QFUQ01CRACO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8488 JY8QFUQ01AK13L productive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaaactca 8489 JY8QFUQ01AXBGY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CSNGYGDFPRR## out-of-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8490 JY8QFUQ01DQK9C No results 8491 JY8QFUQ01CRB0C productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8492 JY8QFUQ01BDA4R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.17.38.11] CAKRWRASNGHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcagctttccatggggtgggtccgccaggctccagggcggggactggagtgggtctcagccattgacggtcttactggtggtacatattacgcggactccgtgaggggccgattcaccatctccagagacgattccaagaacacactgtatctgcaaatgaatagcctgagagccgaggacacagccatatatcactgtgcgaagcggtggcgtgcttccaatggccactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8493 JY8QFUQ01BR7X8 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 934 91.44 203/222 nt 90.99 202/222 nt Homsap IGHJ1*01 F, or Homsap IGHJ4*03 F 93 69.05 29/42 nt 8 10 X 8.10.X [1.17.37.11] CTTESAY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccagggaaggggctggagtggcttggccgtattaaaaggaaagttgatggtgagacaacagactacgctgcatccgtgaagggcagattcaccatctggagagatgactcaaaaacactctatatctgcaaatgaacagcctggaacccgaggacacagccgtatattattgtaccactgaatctgcctattgggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccgctgagcctctgcagcacccaggccatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8494 JY8QFUQ01AUX2R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8495 JY8QFUQ01CIRSH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.02 200/215 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 7 7 11 7.7.11 [2.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) gcctctggattcaccttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8496 JY8QFUQ01CHXOI productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcagg 8497 JY8QFUQ01CHSYW unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 687 80.37 172/214 nt 79.44 170/214 nt Homsap IGHJ2*01 F 148 75.47 40/53 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CARLDGHFD#LW out-of-frame + Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 77 of V-REGION: 'GAA' (3 nucleotides at position 131 to 133 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'T' (1 nucleotides at position 145 to 145 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcgggcttGAAtcgatctccagTagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgactctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8498 JY8QFUQ01C73TC No results 8499 JY8QFUQ01DDHD6 No results 8500 JY8QFUQ01A3RNK No results 8501 JY8QFUQ01CS0KM productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.45 188/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD4-23*01 ORF 2 10 7 17 10.7.17 [1.17.37.11] CARGECGVNCPYYNWYQHW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 126 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacagtgtacaacccctccctcgggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgaggggtgagtgcggtgtcaactgcccctactacaactggtaccaacactggggcccgggaacccgggtcaccgtcacgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8502 JY8QFUQ01COBOK No results 8503 JY8QFUQ01ASNTY unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8504 JY8QFUQ01ALJBN No results 8505 JY8QFUQ01DQBI6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV## out-of-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaacggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8506 JY8QFUQ01DOPE8 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDGGSYNRMDLW in-frame + cgtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcaaggggctggagtggatggcaattatatggtatgatgggaaaaataaatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaattccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccggaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8507 JY8QFUQ01DUIBU productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8508 JY8QFUQ01CO29A productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 71 of V-REGION: 'A' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctAcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8509 JY8QFUQ01C5AY2 No results 8510 JY8QFUQ01DRE2B productive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8511 JY8QFUQ01AEZCS productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 613 97.67 126/129 nt 96.9 125/129 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 X 10 8.X.10 [1.3.31.11] CSNGYGDFPRRW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 37 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcaggagctattggatgagctggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8512 JY8QFUQ01AI4NA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8513 JY8QFUQ01BHJ2H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8514 JY8QFUQ01CCCWM productive (see comment) Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 403 78.79 104/132 nt 78.03 103/132 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 6 18 X.6.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaAatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8515 JY8QFUQ01A5A7Q unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagatccccgaccagccccaaggtcttcccgctgagcctcgacagnaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8516 JY8QFUQ01CWX10 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8517 JY8QFUQ01B6IM7 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDQRSGDA#EAFDIW out-of-frame + stop codons in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcgctatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaaggtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8518 JY8QFUQ01C3F50 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8519 JY8QFUQ01BHRZG unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 115 53.57 75/140 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8520 JY8QFUQ01DROPW unproductive Homsap IGHV3-11*01 F 980 95.35 205/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKDPGGKVGATD#DHW out-of-frame - ctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatccggggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8521 JY8QFUQ01DAHPO unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8522 JY8QFUQ01BHA2F productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 808 88.73 181/204 nt 88.24 180/204 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 11 8.8.11 [2.17.33.11] CATEKPGNEFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 15 nucleotides (from position 157 in the user submitted sequence), (do not cause frameshift) gcgtctggattcaccctcagttcctatgtcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcattggatttaatggacgcagcgagtattatgcagactccgtgaagggccgattcaccatctccagagacaattctctgcaaatgaacaatctgagagtcgaggacacggctgtctattactgtgcgactgagaaacccggcaacgaatttgattactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8523 JY8QFUQ01B9IA6 No results 8524 JY8QFUQ01BZ5ME productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [1.17.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) cgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8525 JY8QFUQ01CUA2E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8526 JY8QFUQ01C3FER No results 8527 JY8QFUQ01CI5PE No results 8528 JY8QFUQ01B7B1B productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8529 JY8QFUQ01B4HQ1 No results 8530 JY8QFUQ01DPZ3N No results 8531 JY8QFUQ01BK4SM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8532 JY8QFUQ01C4FS7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cagcctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8533 JY8QFUQ01BGXQQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagaaccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8534 JY8QFUQ01BEWPJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8535 JY8QFUQ01B47SE No results 8536 JY8QFUQ01BNHM6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 968 94.04 205/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 7 8 10 7.8.10 [2.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift) gcctctggattcatctttgatgatttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaaAttggaatggtggtaaaacaggttatgcagactctgtgaGggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctagtccagggcttcttccccca 8537 JY8QFUQ01BMU57 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 8538 JY8QFUQ01CRX55 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8539 JY8QFUQ01BC4GZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 449 91.51 97/106 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found tctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatacattagtaggagtagtactgacatatact 8540 JY8QFUQ01BBDEH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + ctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 8541 JY8QFUQ01C4KK6 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8542 JY8QFUQ01AUFGY No results 8543 JY8QFUQ01CQ8R1 No results 8544 JY8QFUQ01CXCFY unproductive Homsap IGHV3-74*03 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSGFTRR#YW out-of-frame - gcctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactctgtgaagggccgattcaccatttccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8545 JY8QFUQ01DJCJZ No results 8546 JY8QFUQ01B2JOM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 943 93.9 200/213 nt 92.96 198/213 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 7 7 11 7.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 3 nucleotides (from position 81 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8547 JY8QFUQ01A63Q1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8548 JY8QFUQ01B6C0L productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8549 JY8QFUQ01AQAA0 No results 8550 JY8QFUQ01BD2IQ productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame + tctggatttacctttacaaattattggatgagctgggtccgccaggctccagggaggggcgtggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 8551 JY8QFUQ01DWJC4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8552 JY8QFUQ01CIHIM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8553 JY8QFUQ01A9P0G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8554 JY8QFUQ01CQWF7 unknown (see comment) Homsap IGHV3-74*03 F 129 55.3 73/132 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8555 JY8QFUQ01A12KV productive Homsap IGHV3-48*01 F 815 86.24 188/218 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 8556 JY8QFUQ01DN4IN productive (see comment) Homsap IGHV3-7*02 F 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'CT' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); tctacattcacgtttagtcggtattggatgagctgggtAccgccaggctccaggggaagggcCTgggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8557 JY8QFUQ01DCJWT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 782 86.89 179/206 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 5 8 10 5.8.10 [X.17.38.11] CSKDTFGREDYW in-frame + acttcaatggctttaatatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 8558 JY8QFUQ01AIBQ6 productive (see comment) Homsap IGHV3-72*01 F 961 92.79 206/222 nt 92.34 205/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.16.38.11] CVRDPFSSRGHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 8559 JY8QFUQ01ACH9Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVMREHYYGAGNYPWGGMEVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccatttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8560 JY8QFUQ01BGUSV No results 8561 JY8QFUQ01AGPNS productive (see comment) Homsap IGHV4-61*01 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggttgaacgatgtgaccgctgcggacacggccCatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8562 JY8QFUQ01BVHQU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.16.38.11] CYKRQSVGGT#YW out-of-frame + in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) cctccggattcacctttagtagttactggatgcactgggtccgccaaactccagggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaAgctacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgttacaagagacagtcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctccagcatccccgaccagcccaaggtcttcccggctgagcctcgacagcacccccgcaagatcgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8563 JY8QFUQ01ATXAK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8564 JY8QFUQ01B7VL5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8565 JY8QFUQ01BO056 No results 8566 JY8QFUQ01AU4V8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8567 JY8QFUQ01B6VH0 unproductive Homsap IGHV3-72*01 F 1074 98.21 219/223 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + ctctggattaaccctcagtgaccactacatggactgggcccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8568 JY8QFUQ01BLIES No results 8569 JY8QFUQ01BBQWA No results 8570 JY8QFUQ01CCVT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - cagcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8571 JY8QFUQ01BBNGZ productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 8572 JY8QFUQ01B6YCL No results 8573 JY8QFUQ01B6L7M No results 8574 JY8QFUQ01BT7ZV No results 8575 JY8QFUQ01CK7J8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8576 JY8QFUQ01BN6KV unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 143 59.43 63/106 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 8577 JY8QFUQ01BLH08 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtGgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8578 JY8QFUQ01CPDIO No results 8579 JY8QFUQ01B1JQ7 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 714 85.2 167/196 nt 84.69 166/196 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8580 JY8QFUQ01DNMX7 productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8581 JY8QFUQ01DQA69 No results 8582 JY8QFUQ01DLG7A unproductive Homsap IGHV3-7*01 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*03 F (see comment) 87 64.58 31/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [2.17.38.11] CARATNADV## out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaGgggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctgggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8583 JY8QFUQ01DKDHQ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8584 JY8QFUQ01CL2R1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8585 JY8QFUQ01AIIKB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggaacacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8586 JY8QFUQ01BBKAE No results 8587 JY8QFUQ01BXLBK productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 653 77.52 169/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIIREGLDRW in-frame + Low V-REGION identity (77,52% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) tgtctggtggttctactcgcactaaccattggtggaattgggtccgccagacccccgacaagggactggagtggattggagaagtctataagagtggacagaccaactacaacccgtcactccagagtcgcgttgacctcttcattgacaactccaggaatcagatctccctaaatatgagagatgtgaccgccgcggacacggccgtctattactgcgcgagagaagacattattcgggagggccttgaccgctggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8588 JY8QFUQ01BTLBP No results 8589 JY8QFUQ01CA6DO productive Homsap IGHV3-7*03 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame - tctggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtcccctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8590 JY8QFUQ01CLUBR productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8591 JY8QFUQ01DVSZR unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtgga 8592 JY8QFUQ01AJF0Q No results 8593 JY8QFUQ01C1XQ4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8594 JY8QFUQ01BD9RX No results 8595 JY8QFUQ01BZRJN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARKRVPGGTFYGDYW in-frame - gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgcctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8596 JY8QFUQ01ACLU1 productive (see comment) Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8597 JY8QFUQ01A0TP4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 464 67.89 148/218 nt 66.97 146/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (67,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 37 to 38 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tgtctggattcacatttagaagctattccatgaattTGgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8598 JY8QFUQ01AI4L5 unproductive Homsap IGHV4-61*02 F 960 93.18 205/220 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CARVVRCTTTGCSRVGWFD#PG out-of-frame + ctctggtggctccatcagcagtgatgattactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctcttccagtgggaacaccaactacaacccctccctcaggagtcgagtcaacatttcactagacatgtccaagacccagttctccctggagctgacctctgtgagcgccgcagacacggccgtgtattactgtgcgagggtcgttcgttgtactacgaccggctgctcaagggtaggatggttcgacccctggggccagggaacccgtggtaaccgtctcctcagcatcccccgaccagccccaaggctcttcccgntgagcctcgacagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccc 8599 JY8QFUQ01BPJGG productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + ctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8600 JY8QFUQ01CFLWN productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8601 JY8QFUQ01BM2HZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8602 JY8QFUQ01AWMLK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8603 JY8QFUQ01CHDAZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8604 JY8QFUQ01AMJQ0 No results 8605 JY8QFUQ01A4XAG unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYG#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8606 JY8QFUQ01CQJ2P No results 8607 JY8QFUQ01C4BYC unproductive Homsap IGHV3-11*01 F 904 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.37.11] CARRLLSSGWPPHEWGF# out-of-frame + in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaagggactggagtgggtctcatatattagcagtactggtggttccatatattacgcagactctgtgaagggccgcttcaccacctccagggacaacaccaaaactcaatgtctctgcaaatgaacagcctgagcgtcgacgacacgggcgtctattattgcgcgagaaggcttctcagtagtggatggccaccccacgagtggggcttctgggccagggagtccaggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc 8608 JY8QFUQ01CKSKF No results 8609 JY8QFUQ01BTX1Y productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame - Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8610 JY8QFUQ01AGROF productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8611 JY8QFUQ01B4W9M No results 8612 JY8QFUQ01A544D No results 8613 JY8QFUQ01CN6MQ productive Homsap IGHV2-26*01 F 1080 93.85 229/244 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [9.17.38.11] CARSPSHYSDSFGSYLNKFDYW in-frame + gaccctcacgctgacctgcaccgtctctgggttcttactcagcagtggtaagatgggtgtgagctggatccgtcagcccccagggaaggccctggagtggcttgcacacattttttcgaatggcgataaatcctacaacacatctctgaggagcaggctcaccatctccaaggacacccccaaaagccaggtggtccttaccgtgaccaacgtggaccctgcggacacagccacttattattgtgcacgttctccgtcgcattactcggatagttttggttcttacctcaacaaatttgactactggggtcagggaaccctggtcgccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggtcgtcgtggaactcag 8614 JY8QFUQ01AZUML productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgctctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 8615 JY8QFUQ01AO8BO No results 8616 JY8QFUQ01CK9BK No results 8617 JY8QFUQ01C6JWN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8618 JY8QFUQ01CLEXQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8619 JY8QFUQ01C1E0N No results 8620 JY8QFUQ01CJWU5 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 8621 JY8QFUQ01AGAXJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [2.17.38.11] CAKEGNLGYFDD## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) agcctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 8622 JY8QFUQ01AZU09 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); cgtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtCatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8623 JY8QFUQ01C0MJD productive Homsap IGHV3-30*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + ctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 8624 JY8QFUQ01C4132 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgcttagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8625 JY8QFUQ01DJGCJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8626 JY8QFUQ01CBTTJ unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F (see comment) 624 80.0 156/195 nt 8 7 X 8.7.X [1.17.31.X] null - No rearrangement found Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8627 JY8QFUQ01DGCCW productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacaCgcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8628 JY8QFUQ01A3MT9 productive (see comment) Homsap IGHV4-61*02 F 871 88.29 196/222 nt 87.39 194/222 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [2.17.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); gtctctggtggccccatcagcagcagcacttactactggacttgGgatccggcaggccgccggggagggactggagtggatcggacgtgtttatActtagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8629 JY8QFUQ01AMRYH No results 8630 JY8QFUQ01B5CO0 unproductive Homsap IGHV3-72*01 F 889 89.19 198/222 nt 88.74 197/222 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 3 8 10 X 8.10.X [1.16.38.11] CARDLGNGWGYDY# out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggcttcatcttcagtgaccactatatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagagttgcatctaacacttacgccacagaatacgccgcgtctttcaaaggcagattcgtcatctcaagagacaattcaaggaactcattgtttctccaaatgaacagcctgaaaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctatgactattgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 8631 JY8QFUQ01A7CTP No results 8632 JY8QFUQ01BX0J5 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - tccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8633 JY8QFUQ01BVKMY unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 182 60.0 78/130 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 8634 JY8QFUQ01CMONL unproductive Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGH## out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatgGgaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8635 JY8QFUQ01AH1M8 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.37.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 101 of V-REGION: 2 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8636 JY8QFUQ01A3KYL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8637 JY8QFUQ01C8ANE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDYL# out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactacctgggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtctcccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8638 JY8QFUQ01CMIII productive Homsap IGHV1-2*02 F 1020 97.66 209/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAREHGSGTYSEYFQDW in-frame + tggatacgccttcaccggctactatatgcactgggtgcgacaggcccctggacaagggcttgagtggatggggtggatcaaccctaatagtggtggcacaaactatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggacctgagcaggctgacatctgacgacacggccgtgtattactgtgcgagagaacatggttcggggacttattctgaatatttccaggattggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8639 JY8QFUQ01BT0OK productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt 81.36 179/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaaggGgcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 8640 JY8QFUQ01CK2XZ productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8641 JY8QFUQ01AGSH3 productive Homsap IGHV3-9*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - tctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8642 JY8QFUQ01CB4J1 No results 8643 JY8QFUQ01DJPPU productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame - tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8644 JY8QFUQ01B3B9F productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggaagGtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8645 JY8QFUQ01B7E59 No results 8646 JY8QFUQ01DFN6M No results 8647 JY8QFUQ01CXRCB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8648 JY8QFUQ01C4N1G unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 116 54.14 72/133 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 8649 JY8QFUQ01B37IT productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8650 JY8QFUQ01CMV96 No results 8651 JY8QFUQ01CE9LJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8652 JY8QFUQ01A8WS2 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8653 JY8QFUQ01CI6C5 productive Homsap IGHV2-5*01 F 998 90.5 219/242 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [8.17.38.11] CVQSHYYDNSGYFVSW in-frame + ccctcacgctgacctgcgacttctctgggttctcactcaccactagtggagtgggtgtggcctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttactggaacaatgatcagcgctatagcccatctctgaagaacaggctcaccatcagtcaggacagctccaaaaatcaggtcgtccttacagtgaccaatatggaccctgtggattccgccacatacttctgtgtccaaagtcactactatgataatagtggttactttgtttcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8654 JY8QFUQ01BI6RT productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARERGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8655 JY8QFUQ01B8C9Z unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F (see comment) 458 67.91 146/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (67,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8656 JY8QFUQ01BUW74 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8657 JY8QFUQ01C2LSU No results 8658 JY8QFUQ01CTDZI unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1014 95.91 211/220 nt 95.45 210/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.16.38.11] CVRGDYGGDPRTLLRP#YGLDVW out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cagcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgacccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8659 JY8QFUQ01AS28D productive Homsap IGHV3-23*03 F (see comment) 522 71.43 155/217 nt Homsap IGHJ2*01 F 166 79.25 42/53 nt Homsap IGHD3-3*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARVRNSNWYFDHW in-frame + Low V-REGION identity (71,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgaagacatgtttaagagtttcggattgacgtgggtccgtcaggctccagggaaggggctggagtgggtcgcaggaataaacaattacaatggtgcaactttctatgctggccccgtaaagggccgcttcaccgtctctcgagataaagaaaagaccattttttatctacaaatggacaacgtgagggtcgacgacacgggcgtttatttctgtgcgagagtcaggaatagtaattggtacttcgaccactggggccgcggcgcactagtcacagtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8660 JY8QFUQ01AG60V productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8661 JY8QFUQ01A4A0M No results 8662 JY8QFUQ01CFE1A No results 8663 JY8QFUQ01DQ9QD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgtgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8664 JY8QFUQ01DNFAX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATRNKMGISTPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); cctctggattcaccGttcagtagatactggatgcactgggtccgccaggctcctgggaAaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccggttcaccatctccagagacaactcccagactacgctgAtttttggagatgagcagcctgagagacgaggacacggccgtatattactgtgcgacaaggaataaaatgggaattagtacgcctgttgactactggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8665 JY8QFUQ01A8KHD productive Homsap IGHV3-9*01 F (see comment) 793 84.93 186/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [2.17.38.11] CGRIAKPGLGALDLW in-frame - Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8666 JY8QFUQ01A2ECA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8667 JY8QFUQ01CLSYK No results 8668 JY8QFUQ01AKBIM productive Homsap IGHV3-48*01 F 886 90.28 195/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 8669 JY8QFUQ01ABCA0 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-16*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYESTYPW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggctggagtgggttggccgcatcaagagcacctctgatggtgggacaacagactccattgcacacgtcaaagacagattcatcatctcaagagatgattcaagaaatacactgtacttacaaatgaacaacctgagagtcgaggatacaggcgtctattattgttccacaggagggccaaatggttatgagtctacctatccctggggcccgggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcaacacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8670 JY8QFUQ01BFYTP unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 1 8 7 20 8.7.20 [1.17.38.11] CAREPPRLL*WWLLFVGAFDIW in-frame - stop codons in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattacCtggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccCttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagaacccccgagactattgtagtggtggttactgtttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggactgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8671 JY8QFUQ01BQR98 No results 8672 JY8QFUQ01DLA93 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8673 JY8QFUQ01CCFI9 No results 8674 JY8QFUQ01AF4ER productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8675 JY8QFUQ01CXPDA unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt 93.27 208/223 nt Homsap IGHJ4*02 F 199 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTDPRYFWG*R#FDYW out-of-frame + stop codons in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); ctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaaTcacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggtagcgggtttgactactggggccagggaaccctggtcaccgtctcctnagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8676 JY8QFUQ01AU855 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8677 JY8QFUQ01B1OZO unknown (see comment) Homsap IGHV3-7*01 F 1026 96.77 210/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8678 JY8QFUQ01C98V3 No results 8679 JY8QFUQ01B92QK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8680 JY8QFUQ01A6WOJ No results 8681 JY8QFUQ01C878R productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTRGGYSYAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatgctatgagttggttccgccaggctccagGggaaggggctggagtgggtaggtttcattggaggcagagctcatggtggggcaacagaatacgccgcgtctgtgaaaggcagattcatcatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtactagagggggatacagttatgcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8682 JY8QFUQ01DDO4Z No results 8683 JY8QFUQ01BQWUF No results 8684 JY8QFUQ01B5EL3 productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - cctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8685 JY8QFUQ01DWKI0 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 943 93.9 200/213 nt 93.43 199/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 X 8.7.X [1.17.38.11] CARGTGLR#DYW out-of-frame + in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); tctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattGcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagagggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8686 JY8QFUQ01C4S9T productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 963 92.04 208/226 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION gccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8687 JY8QFUQ01BI4NH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tttcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactc 8688 JY8QFUQ01BIBXR productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggccatcgcctgcctggtccagggcttcttccccca 8689 JY8QFUQ01ARGPK No results 8690 JY8QFUQ01AOP9S No results 8691 JY8QFUQ01BRRVB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8692 JY8QFUQ01AZBTF No results 8693 JY8QFUQ01AR9V6 productive Homsap IGHV3-21*04 F 937 92.24 202/219 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARAVSNQVDVW in-frame - gcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8694 JY8QFUQ01DCOWC No results 8695 JY8QFUQ01AR6RC productive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CTRDDRSVRGVTSDYW in-frame + ctctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatttttgtacgagagatgatcgctcggttcggggagtcacctcagactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8696 JY8QFUQ01C0BGL No results 8697 JY8QFUQ01C13EL productive Homsap IGHV1-8*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CAREGLLGSLGSW in-frame - aggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8698 JY8QFUQ01C3Q8J unproductive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGRKMATSAS#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcgaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8699 JY8QFUQ01DNWE3 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 134 63.29 50/79 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8700 JY8QFUQ01AHITW unproductive (see comment) Homsap IGHV2-5*01 F 1044 92.21 225/244 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [9.17.38.11] CAHSPP*P#NWFDLW out-of-frame - stop codons gaccctcactctgacctgtaccttctctgggatttcactcaccactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggaatggcttgcactcatttattggaacgatgagacgcgctacagtccatctctgagggacaggctcaccatcagcaagggcacctctaaaaaccaggtggtccttacgatgaccaacatggaccctgtggacacggccacatattactgtgcacacagccccccttagcccagaattggttcgacctctggggccagggctccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8701 JY8QFUQ01DCC58 unproductive Homsap IGHV3-7*03 F 842 87.61 191/218 nt Homsap IGHJ5*01 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CTRRGFMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 8702 JY8QFUQ01A8IJI No results 8703 JY8QFUQ01B00R6 productive Homsap IGHV3-11*01 F 855 88.48 192/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + ctctggattcaccttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggaatggatctcatatatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 8704 JY8QFUQ01DQ6JD unproductive (see comment) Homsap IGHV3-48*04 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - stop codons in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtatctatGcccatgacctgggtccgccaggctccagggaaggggctggagtgatttcagtttatcactgataggggtagtacccaatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8705 JY8QFUQ01BDLXF No results 8706 JY8QFUQ01BKM4D No results 8707 JY8QFUQ01BJAAN unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8708 JY8QFUQ01BR23F productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 866 88.24 195/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) aggcctcctggattcaccCtttggttattatggcatggactggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 8709 JY8QFUQ01CL9VP productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*07 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 34 of V-REGION: 5 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) tctggattcaccgtcaactagaaactacatgagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8710 JY8QFUQ01C5A8M No results 8711 JY8QFUQ01AWF0A productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8712 JY8QFUQ01AD3IP No results 8713 JY8QFUQ01C9DGQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 8714 JY8QFUQ01DILKD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggctgacggtgtcgtggaactca 8715 JY8QFUQ01AQJ8I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8716 JY8QFUQ01CH3BJ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 850 88.43 191/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame - tctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctccttcaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8717 JY8QFUQ01DGNVX unproductive (see comment) Homsap IGHV3-9*01 F 445 90.74 98/108 nt 89.81 97/108 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [1.15.11.11] CAKDGSAIPVTGTYFEYW in-frame + stop codons in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8718 JY8QFUQ01AT9J8 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8719 JY8QFUQ01CKPOL No results 8720 JY8QFUQ01BSXDU No results 8721 JY8QFUQ01AGMDN No results 8722 JY8QFUQ01CRXFK productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8723 JY8QFUQ01AL8UN productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame - tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8724 JY8QFUQ01DHN9E productive Homsap IGHV4-34*08 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + ctctggattcacctttggtagctattggatggcctggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8725 JY8QFUQ01CJJ54 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaCcctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 8726 JY8QFUQ01B1XHB productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [2.16.38.11] CAKNGPGGGWYAEQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcgtctggattcagtttcagtgactatgccatgcactgggtccgccagactccaggcaagggctggagtgggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaaaatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8727 JY8QFUQ01CTT6Y productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8728 JY8QFUQ01A8IV0 No results 8729 JY8QFUQ01CFHCJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - gtctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccatggcttcttccccca 8730 JY8QFUQ01CLD9L productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8731 JY8QFUQ01COTXW productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaact 8732 JY8QFUQ01BP3Y5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8733 JY8QFUQ01DP4NP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARSKYSLGRLPDF## out-of-frame + ctctggattcattttcaacactcatgccatgacttggctccgccaggctccagggaaggggctggagtgggtctcagccattagtggcgatgctactggcactttttacgcagactccgtgaagggccggttcaccatctccagagacaatgtcaagaacacggtggatttgcagatgaacaacgtgagagtcgaggacacggccttatattactgtgcgaggagcaaatatagtcttggccgcttacctgacttctggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8734 JY8QFUQ01AV7G8 No results 8735 JY8QFUQ01BICQI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANACPPYNWN#YFYYYGMDVW out-of-frame - tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctgccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8736 JY8QFUQ01CO9YE productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt 89.09 196/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8737 JY8QFUQ01C8DQF productive Homsap IGHV4-61*02 F 960 93.18 205/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame - ctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8738 JY8QFUQ01DFQZY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8739 JY8QFUQ01DMA0D unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 8740 JY8QFUQ01DS7GW unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac 8741 JY8QFUQ01DE480 productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccga 8742 JY8QFUQ01AK37Y productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 8743 JY8QFUQ01ARYWV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame + tctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttctt 8744 JY8QFUQ01DRUC1 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8745 JY8QFUQ01DOFPT No results 8746 JY8QFUQ01BJ5BD No results 8747 JY8QFUQ01BX25Z No results 8748 JY8QFUQ01BIWZU No results 8749 JY8QFUQ01AKUKJ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 957 92.38 206/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8750 JY8QFUQ01DG5KX productive Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgcagcagcccctaaggtcttccgctgagcctcgacacgcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8751 JY8QFUQ01C8CMM unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 125 100.0 25/25 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tccggggacagtgtctctagcaaca 8752 JY8QFUQ01B3AYN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gcctctggattcaccGttcagtagatactggatgcactGgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8753 JY8QFUQ01AN3PN No results 8754 JY8QFUQ01CMNEA No results 8755 JY8QFUQ01A7PTY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRSGRDGG#WFDSW out-of-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatggggggcctggttcgactcctggggccagggaacccgtggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8756 JY8QFUQ01B37ED unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 8757 JY8QFUQ01CXOED unproductive Homsap IGHV3-48*01 F 1066 99.54 215/216 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGSGWYRDFDY# out-of-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgagaggcagtggctggtacagggactttgactactgggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8758 JY8QFUQ01DLZRP unknown (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccgaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 8759 JY8QFUQ01DRK6U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggctatagcagcgaacgaaactactggggccagggaagccctggctcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8760 JY8QFUQ01BKDJ4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8761 JY8QFUQ01BWN2J productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8762 JY8QFUQ01AE4C2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARASTLRYLDRW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctggatttacattagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgaggggccgcttcaccatctctagagacgacgccaagaattcactttatctgcagatgaacaacctgagaggcgaggacacggctgtctatttttgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8763 JY8QFUQ01BA0MC productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8764 JY8QFUQ01ASM5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.09 198/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CAKGYHGPFDSW in-frame + ctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8765 JY8QFUQ01BYKTM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8766 JY8QFUQ01DSMIM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8767 JY8QFUQ01ANF7B unknown (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctcttccaccaagggcccatccgtcttccccctggcgcccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca 8768 JY8QFUQ01ATBJS No results 8769 JY8QFUQ01DDV0C productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8770 JY8QFUQ01BIVWL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8771 JY8QFUQ01CFEQP unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 259 69.91 79/113 nt 8 8 X 8.8.X [0.17.4.X] null - No rearrangement found Low V-REGION identity (69,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8772 JY8QFUQ01AKRAQ productive (see comment) Homsap IGHV1-8*01 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-10*01 F 3 8 8 17 8.8.17 [0.17.38.11] CARGPDEGPLYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'AGG' (3 nucleotides at position 185 to 187 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccaattatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaaaattggaaacacaggctctgcacagaagttccagggcagagtcaccatgaccaggaacacctccacaagcactgcctacatggagctgagcggcctcAGGaagtctgacgacacggccgtatattactgtgcgagagggccggatgagggtcccctttactactattatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8773 JY8QFUQ01CH4RG No results 8774 JY8QFUQ01A098V No results 8775 JY8QFUQ01DL72Y No results 8776 JY8QFUQ01AKV85 unproductive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASNFWSGSPG##YYYGMDVW out-of-frame - cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgaatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8777 JY8QFUQ01BEJX1 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 135 77.78 35/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgcca 8778 JY8QFUQ01BTDTI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccatggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8779 JY8QFUQ01CPDBH No results 8780 JY8QFUQ01BXNFF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + tctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8781 JY8QFUQ01CIGNE productive Homsap IGHV3-11*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARVKYSSSWSSILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcattcattagtagtcctggtatcaggagtttctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8782 JY8QFUQ01DWRPB No results 8783 JY8QFUQ01CC4CT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDRYPRSTAITAPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'CA' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gcctctggCAttccccgtttagcaactGatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8784 JY8QFUQ01AIK4Q productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8785 JY8QFUQ01B56HH productive Homsap IGHV2-5*02 F 1134 96.31 235/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [9.17.38.11] CAHRGNYGDYVFDSW in-frame + gaccctcacgctgacctgcaccttctctggattctcacttagcactagtgggatgggtgtgggctggatccgtcagcccccaggaaaggccctggaatggcttacactcatttattgggatgatgataagcgctacagcccatctctgaagagcaggctcgccatcaccaaggacacctccaaaaatcaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattattgtgcacacagagggaattacggtgactatgtttttgactcctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 8786 JY8QFUQ01BU46G productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCgggggggcactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 8787 JY8QFUQ01B2W2D No results 8788 JY8QFUQ01BUXGM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 2 8 10 14 8.10.14 [0.17.38.11] CTTRPRGWEPLGLDYW in-frame - ctggattcactttcagtaacgcctggatgatctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagaccaaagctgatggtgcgacaacagactactctgcacccgtgagaggcagattcatcatctcaagagatgattcaaaaaacatggcgtttctgcaaatgaacagcctgaaaaccgaggacacagccctttattactgtaccacacggccccgggggtgggaaccacttgggctcgactactggggcctgggaaccctggtcaccgtctcctctgcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8789 JY8QFUQ01B2GCQ No results 8790 JY8QFUQ01AGKW1 No results 8791 JY8QFUQ01BUO7F No results 8792 JY8QFUQ01A4DRB unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcgggtcaccgtcctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8793 JY8QFUQ01CAFZQ No results 8794 JY8QFUQ01CWH2P No results 8795 JY8QFUQ01BGO9W No results 8796 JY8QFUQ01C03N1 No results 8797 JY8QFUQ01A3V1E productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8798 JY8QFUQ01A365U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8799 JY8QFUQ01CIFO7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8800 JY8QFUQ01B5U19 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - gcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8801 JY8QFUQ01B5I6A unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGL*QWL##DFDCW out-of-frame + stop codons ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8802 JY8QFUQ01DIO55 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 8803 JY8QFUQ01AMI0B productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8804 JY8QFUQ01CK79T unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEEGATGVYYVDH# out-of-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8805 JY8QFUQ01ADRIZ No results 8806 JY8QFUQ01CPP87 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 107 57.95 51/88 nt 8 2 X 8.2.X [2.17.X.X] null - No rearrangement found stop codons cctcctggattcacctttagcagctatgccatgagctgggctcaagggactacttccccgaaccggtgacggtgtcgtggaactccag 8807 JY8QFUQ01BX6JB productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 8808 JY8QFUQ01DRVPT No results 8809 JY8QFUQ01CEGRO No results 8810 JY8QFUQ01BARWR No results 8811 JY8QFUQ01CDELV productive (see comment) Homsap IGHV3-48*03 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 7 8 13 7.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagttcttatgcatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8812 JY8QFUQ01C64L9 No results 8813 JY8QFUQ01A82RW productive Homsap IGHV3-30*10 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-9*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARDRDFDFPAYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacttcagtaactatgctgtgcactgggtccgccgggctccaggcaaggggctagagtggatgggagttatatcatttgatggagataataaatactacacagactccgtgaagggccgattcaccatgtctagagacaattccaagaacacactatatctccaaatgaacagcctgtcagctgaggacacggctgtctattactgtgcgagagatcgagatttcgactttcctgcttacggtttggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8814 JY8QFUQ01CPWUK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1041 97.27 214/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8815 JY8QFUQ01BJYDO productive Homsap IGHV1-3*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGEPLGGDYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcacttcttatgctgtaaactgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagtttcagggcagagtcaccattaccagggacacatccgcggacacagtcttcatggagctgagcagtctaagatctgaagacacggctgtgtattattgtgcgagagatggggagccactgggaggcgactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8816 JY8QFUQ01C6MWX No results 8817 JY8QFUQ01BNVJT No results 8818 JY8QFUQ01AEUM3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8819 JY8QFUQ01BVL9C productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGYW in-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8820 JY8QFUQ01AT3EI No results 8821 JY8QFUQ01CM72D productive Homsap IGHV3-48*04 F 900 90.78 197/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8822 JY8QFUQ01C3CHZ productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctggctgcctggcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8823 JY8QFUQ01AQ049 unproductive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGKAGHTHYGLDV## out-of-frame + ctctgcattcaccttcagtagttatgctatgcactgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8824 JY8QFUQ01BXLFA productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD5-18*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARSGDPGMVHGVYYYNIDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tctggaattcaccttcagaagctatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagtaacatatactatgcagactcagtggagggccgattcaccatctccagagacaacgccaagaattcactgtttctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatctggggatccaggtatggttcatggcgtgtactactacaatatagacgtctggggccaagggaccacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8825 JY8QFUQ01BS2DY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 616 75.93 164/216 nt 75.46 163/216 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8826 JY8QFUQ01BS3ZN unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 650 76.92 170/221 nt 76.47 169/221 nt 10 7 X 10.7.X [2.16.38.X] null - No rearrangement found Low V-REGION identity (76,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtagtagttactactgggcctggatccgccagccccagggaaggggctggagtgccttgggagcatcttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccttatccgttgacacttccaagaaccagttctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8827 JY8QFUQ01DG7LK No results 8828 JY8QFUQ01DL61R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtAgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8829 JY8QFUQ01ARGUK No results 8830 JY8QFUQ01CYMNK No results 8831 JY8QFUQ01AG3HE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + ctctggattcaccttcagtaactacagaatgaattgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgcccagaactcgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8832 JY8QFUQ01ACPNW unproductive Homsap IGHV3-66*02 F 894 91.12 195/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKLADTGEWSNRIFYF# out-of-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatattacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8833 JY8QFUQ01DBJFZ unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 90 81.48 22/27 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctccgggggacagtgtctctaccaaca 8834 JY8QFUQ01BZFIM productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8835 JY8QFUQ01AJ0AZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.16.38.11] CAKEEVWYGSGRGGPKDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGA' (3 nucleotides at position 90 to 92 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) gcctctggattcacctttaggagctatgccagagctgggtccgccaggctccagggaagggggctgagtgggtctcaactattagtggtGGAaatgttgatagcacagactacgcagattccgtgaagggccggttcaccatctccagagacaattccaagaacacattgtatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaaagaagaagtgtggtatggttcggggagaggggggccaaaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8836 JY8QFUQ01BEABE productive (see comment) Homsap IGHV3-7*01 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARVNKDSTDMW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaagggggctggagtAgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8837 JY8QFUQ01CUDXR No results 8838 JY8QFUQ01B4Z8J No results 8839 JY8QFUQ01DL6YG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRRGPNDY## out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcggcggggacctaatgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8840 JY8QFUQ01A36OR productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8841 JY8QFUQ01ALH3K unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8842 JY8QFUQ01BDE6W No results 8843 JY8QFUQ01BZJD6 productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*08 F 856 90.0 189/210 nt 88.57 186/210 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-13*01 F 1 8 7 13 8.7.13 [1.15.38.11] CARKYGSSTNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 31 of V-REGION: 'T' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 7 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 4 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagTcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcatttattgggatgatgataagcgctacaacccatctctgaagagcaggctcaccatcaccaaggacacctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattattgtgcacgcaagtacggcagcagcacgaattggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 8844 JY8QFUQ01DHRRE No results 8845 JY8QFUQ01BDGRO productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame - Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg 8846 JY8QFUQ01DDD10 No results 8847 JY8QFUQ01AEPJ7 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F or Homsap IGHV4-31*06 F or Homsap IGHV4-31*08 F 834 86.82 191/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGRPSDRGEYYFDYW in-frame + ctctggcgcctccatcagcagtggtctttactactggagctggatccgccaattcccagggaggggcctggaatggattggattcactctttacagtgggagcacccactacaacccgtccctcaagagtcgacttaggatttctatagacacgtcaaagaaccagttctccttgaatctgacttctgtgactgccgcggacacggccgcatattactgtgcgagaggtcgcccttcggatcggggagaatactactttgactactggggtcaggcaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8848 JY8QFUQ01CEMBF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 391 88.78 87/98 nt 86.73 85/98 nt 7 7 X 7.7.X [1.16.X.X] null + No rearrangement found in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcaccttggcagctatatcatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtaggggtgttgaca 8849 JY8QFUQ01ADQXM No results 8850 JY8QFUQ01DARQJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [1.17.38.11] CARGGGGKSIPLDNW in-frame + gtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 8851 JY8QFUQ01BXI8V unproductive (see comment) Homsap IGHV3-11*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKDPGGKSGSYGLDHW in-frame - stop codons in FR3-IMGT at codon 80 of V-REGION: 'A' (1 nucleotides at position 145 to 145 in the user submitted sequence), (cause frameshift); gcctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccAagggtcaacgccaagaactcactgtctctgtaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatccggggggaaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8852 JY8QFUQ01A2HU3 productive (see comment) Homsap IGHV4-4*07 F 828 87.1 189/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); tgtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8853 JY8QFUQ01B81HO productive (see comment) Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt 80.65 175/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctctggattCccccttcaatatatggagcatgaattgggtccgccaggctcCcggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8854 JY8QFUQ01CL33K unknown (see comment) Homsap IGHV1-2*02 F 503 86.47 115/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc 8855 JY8QFUQ01BULPN No results 8856 JY8QFUQ01DKQ6P productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8857 JY8QFUQ01APZAR unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 558 72.81 158/217 nt Homsap IGHJ1*01 F (see comment) 19 63.64 7/11 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (72,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity). The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 8858 JY8QFUQ01B74B9 unproductive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKIGRAAAGPILR#W out-of-frame + ctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8859 JY8QFUQ01COHK1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKYPSISGWYTP#NWFDPW out-of-frame - ggctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatacccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8860 JY8QFUQ01C8695 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 837 87.56 190/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggatacacctttggcattcactggattgcctgggtgcgccagaagcccgggaaaggcctagagtggatggggatcatctatccaggcgactctgacaccacatacagtccgtccttccaaggccaagtcaccatctcagtcgacaagtccagcaataccgcctatttacagtggatcagcctgagggcctcggacaccgccatgtattattgtgtgagacggggccagacaagataccgactcgtctgaagctttgacatttggggccaagggacaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8861 JY8QFUQ01DH7XB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGQFGTVMDYW in-frame - ctctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggatggggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgttttttattgtgcgaaaggccagtttggtaccgtcatggactattggggccagggaacccaggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8862 JY8QFUQ01DHA6Y unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 102 53.03 70/132 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8863 JY8QFUQ01A3W23 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 237 60.12 101/168 nt 8 8 X 8.8.X [0.17.22.X] null + No rearrangement found Low V-REGION identity (60,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8864 JY8QFUQ01AT86Y No results 8865 JY8QFUQ01A5D0V No results 8866 JY8QFUQ01APZ3Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGICYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'CA' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); cctctggattcCAgcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtatatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8867 JY8QFUQ01BLQB5 No results 8868 JY8QFUQ01DLU9F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8869 JY8QFUQ01BE4VS productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8870 JY8QFUQ01DS5CD No results 8871 JY8QFUQ01DUXI2 unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CARPHI*QRPGR#FDTW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggccccacatatagcagcggccgggacgctttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8872 JY8QFUQ01ACLY7 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatCccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8873 JY8QFUQ01BPL16 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 8874 JY8QFUQ01AW5C9 No results 8875 JY8QFUQ01CZXNB productive Homsap IGHV3-9*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAKGGGNGDLDYW in-frame - tggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8876 JY8QFUQ01CPGIT productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 90.58 202/223 nt 89.24 199/223 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-22*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTSRYYDPSGYWSDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'C' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 94 of V-REGION: 'G' (1 nucleotides at position 196 to 196 in the user submitted sequence), (cause frameshift); ctctggggtcaccttcagtgacgcctggatgacctgggtccgccaggctccagggaaAGggggctggagtgggttggccgtattagaagcagagttgatggtgggacagtggactacgctgcacccgtgaaaggcagattcaccatctcaagagatgaCtccgaaaaacacactatatctacaaatgaacagcctGgaaaatcgaggacacagccatgtatttctgcaccagtcgatactatgatcctagcggttactggtccgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8877 JY8QFUQ01ADX4W productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggGggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 8878 JY8QFUQ01BCO3O productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 862 89.67 191/213 nt 89.2 190/213 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.37.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) ctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 8879 JY8QFUQ01BLGQV unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKGTWIQ*LRP#DYW out-of-frame + stop codons Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaagggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctgcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8880 JY8QFUQ01CT2Y2 productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); cctctggattcccttttagaacctattggatgagttGgggtccgccaggctccagggGAaaggggctggagtGgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcagg 8881 JY8QFUQ01CYU3K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8882 JY8QFUQ01DTLJ4 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DTLJ4 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8883 JY8QFUQ01DL9FI unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFL##YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgaccctttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8884 JY8QFUQ01A4FR2 unproductive Homsap IGHV3-66*02 F 876 90.19 193/214 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAALHDPPWGWLD#PG out-of-frame + ctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8885 JY8QFUQ01AC0N1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8886 JY8QFUQ01C5WBE No results 8887 JY8QFUQ01BNHDT No results 8888 JY8QFUQ01CY19E No results 8889 JY8QFUQ01C67S6 No results 8890 JY8QFUQ01APJQA unproductive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGAGLDV## out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctgggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 8891 JY8QFUQ01B383T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8892 JY8QFUQ01DLITF No results 8893 JY8QFUQ01A8T70 No results 8894 JY8QFUQ01AI35Q unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8895 JY8QFUQ01A4P7X productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8896 JY8QFUQ01B98PC No results 8897 JY8QFUQ01DGLEH productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8898 JY8QFUQ01CCDJP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagAccctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8899 JY8QFUQ01ASBMB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 880 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8900 JY8QFUQ01DASVR productive Homsap IGHV1-2*02 F 970 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARSTWRGAPDYW in-frame - tggatacaccttcaccggctactatatgcactgggtgcganaggcccctggacaaggccttgaatggatgggatggaccaaccctaacggtggtggcgcaaactatgcacagaagtttaagggcagggtcaccttgaccagggacacgtccatcagcacagcctacatggagctgagcaggctgaggtttgacgacacggccgtgtatttctgtgcgagatcgacctggagaggggcacctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8901 JY8QFUQ01DRJW6 No results 8902 JY8QFUQ01AD5QJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame - ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8903 JY8QFUQ01ATT5V productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 8904 JY8QFUQ01A13CK productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + cctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8905 JY8QFUQ01BIL8C unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaagaggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8906 JY8QFUQ01BWZ5H productive Homsap IGHV3-9*01 F 810 86.18 187/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame + ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8907 JY8QFUQ01B6ODL No results 8908 JY8QFUQ01CAR1O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CAKDRDPGYCLSNSCVDGLAFDSW in-frame + cctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggtggtaacacatacttcgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtttctacagctgaacagcctgagagccgccgacacggccgtatattactgtgcgaaggatcgtgacccgggatattgtcttagtaatagctgtgttgacggcctagcctttgactcctggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8909 JY8QFUQ01C44TZ productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8910 JY8QFUQ01DME8N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + ctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8911 JY8QFUQ01APK0W productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8912 JY8QFUQ01CUUTL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8913 JY8QFUQ01BUNVH productive (see comment) Homsap IGHV3-33*03 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 7 16 8.7.16 [1.16.38.11] CAREVKYGDDTGGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtggtggcaatgattggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagagaggtgaaatacggtgacgacacgggggggtggttcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccccagg 8914 JY8QFUQ01ARRB2 unknown (see comment) Homsap IGHV3-48*01 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcagcttcagttcctatagcatgagctgggtccgccaggctccggggaaggggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctgtcaggcttcttcccccaa 8915 JY8QFUQ01AUQPF productive Homsap IGHV3-48*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8916 JY8QFUQ01AL0GI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8917 JY8QFUQ01CIW9M unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 650 78.77 167/212 nt 77.83 165/212 nt 8 8 X 8.8.X [0.16.38.X] null - No rearrangement found Low V-REGION identity (78,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 2 nucleotides (from position 74 in the user submitted sequence), (cause frameshift) tggattcagctttagcgattttgccatgagttgggtccgccaacctccaggAaaaggggctggagtgggtcgcaaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8918 JY8QFUQ01AT53V No results 8919 JY8QFUQ01ADAE7 productive (see comment) Homsap IGHV2-5*02 F 1080 93.85 229/244 nt 93.44 228/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 12 10.7.12 [9.17.38.11] CAHSVNSWTNFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'GTTCTCA' (7 nucleotides at position 32 to 38 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttcactgggGTTCTCActcacactcaccactagtggagtgggtgtgggctgggtccgtcagcccccaggcaaggccctggagtggctcgcaatcatttattgggatgatgataagttctacagtccatctctgaagagcagactcaccatcaccaaggacacctccaaaaaccaagttgtccttacaatgaccaacatggaccctgtggacacagccacatattattgtgcacacagtgtcaacagttggaccaattttgaccactggggcccgggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 8920 JY8QFUQ01BPEPF No results 8921 JY8QFUQ01C17CH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 484 82.86 116/140 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 8922 JY8QFUQ01A5H2V No results 8923 JY8QFUQ01A96T1 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARDPSGSGWAFESW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'AT' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift); gcgtctggaATttccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8924 JY8QFUQ01AJDLF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [2.17.38.11] CATDGVGSTVKLMVMGPF#DFR out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'GGG' (3 nucleotides at position 61 to 63 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); gcctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccaggggaaGGGggtttggagtggGgtctcatctattagtactagtggGgactaactcatactacgcagactccgtgaaggGgccggttcaccatctccagagacaattccaagcaagcgctttatctgcagatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttggacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8925 JY8QFUQ01C74KW unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8926 JY8QFUQ01ACFWW unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 173 55.43 97/175 nt 8 7 X 8.7.X [1.17.25.X] null - No rearrangement found ctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 8927 JY8QFUQ01CEWZT unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8928 JY8QFUQ01CM7EV productive (see comment) Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGKAGHTHYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctgcattcaccttcagtagttatgctatgcactgggtccgccaggGccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8929 JY8QFUQ01DQTLP productive Homsap IGHV3-48*04 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8930 JY8QFUQ01CHPZ5 No results 8931 JY8QFUQ01CY8AI productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8932 JY8QFUQ01DSBEC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + cctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8933 JY8QFUQ01CW8PV productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8934 JY8QFUQ01DI3HO productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 8935 JY8QFUQ01CQTPI productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8936 JY8QFUQ01DAX0B No results 8937 JY8QFUQ01C113H productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'GTC' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggctggGagtgggGTCagtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8938 JY8QFUQ01CT1KY unproductive (see comment) Homsap IGHV3-66*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 X 8.7.X [1.17.38.11] CVGDRQKG*LFR#YW out-of-frame + stop codons cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 8939 JY8QFUQ01CSIS8 No results 8940 JY8QFUQ01BC1NA productive Homsap IGHV4-61*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + ctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8941 JY8QFUQ01AM81W unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8942 JY8QFUQ01BX45F unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRHTAMERGDY## out-of-frame + ttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggccccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8943 JY8QFUQ01BLWYE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8944 JY8QFUQ01A50CS unknown (see comment) Homsap IGHV3-74*03 F 99 52.59 71/135 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8945 JY8QFUQ01BX688 productive Homsap IGHV3-7*01 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSAYFSTGYW in-frame - agcctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 8946 JY8QFUQ01BX57K No results 8947 JY8QFUQ01AH715 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 15 7.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8948 JY8QFUQ01BUQAY productive (see comment) Homsap IGHV4-38-2*01 F, or Homsap IGHV4-38-2*02 F 815 86.24 188/218 nt 84.4 184/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 9 7 15 9.7.15 [1.17.38.11] CAREGDGYIYKRSFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CAC' (3 nucleotides at position 26 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'ACT' (3 nucleotides at position 95 to 97 in the user submitted sequence), (do not cause frameshift); tctctgacgactccatcagcagtggCACttactactgggAgttggatccggcagcccGccggggaaggctccggagtggattggccgcttctatACTattactgggcgcaccaactacaatccctccctcgagagtcgagtcaccataacaagggacgtgtccaagaatcagttctccctgagactgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagggggatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8949 JY8QFUQ01CGPB2 No results 8950 JY8QFUQ01A0HBK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 8951 JY8QFUQ01CL1S7 No results 8952 JY8QFUQ01A313H No results 8953 JY8QFUQ01A2FC1 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8954 JY8QFUQ01AY5WJ unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 623 75.68 168/222 nt 75.23 167/222 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [3.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - stop codons Low V-REGION identity (75,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); ctctggattcagcgttaagttcgttatgggcatntaactggggtccgccaggctccatggggggggctggGagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8955 JY8QFUQ01A4MJ5 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8956 JY8QFUQ01A21XY unproductive Homsap IGHV3-33*03 F 918 91.71 199/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRGCTNGACYVADF## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaactattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggcccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8957 JY8QFUQ01AWUJ4 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); tctgattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatCccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8958 JY8QFUQ01BON36 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8959 JY8QFUQ01BJJ62 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8960 JY8QFUQ01AD4BK No results 8961 JY8QFUQ01B4PD9 productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8962 JY8QFUQ01C09UG No results 8963 JY8QFUQ01CITN1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggctgacggtgtcgtggaactcag 8964 JY8QFUQ01APN0I No results 8965 JY8QFUQ01DAEQZ unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtGaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8966 JY8QFUQ01BF5OD productive Homsap IGHV3-49*04 F 994 93.78 211/225 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [2.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttagagactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8967 JY8QFUQ01CW5KL No results 8968 JY8QFUQ01BE62D productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccTgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 8969 JY8QFUQ01BAGNX No results 8970 JY8QFUQ01B6HAI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 620 93.01 133/143 nt 91.61 131/143 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 7 1 X 7.1.X [1.X.38.11] CVSDLAGQKGF## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01B6HAI ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) cctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8971 JY8QFUQ01BKF4E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 8972 JY8QFUQ01BZ6BK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 835 88.26 188/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [X.17.38.11] CAKEEGATGVYYVDHW in-frame + ggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgagtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8973 JY8QFUQ01BJNET unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 760 83.8 181/216 nt 83.33 180/216 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggtttggcgtgaactaggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8974 JY8QFUQ01BO31O productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 653 77.52 169/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*02 F 3 9 7 12 9.7.12 [1.17.38.11] CARENIIREGLDRW in-frame + Low V-REGION identity (77,52% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) tgtctggtggttctactcgcactaaccattggtggaattgggtccgccagacccccgacaagggactggagtggattggagaagtctataagagtggacagaccaactacaacccgtcactccagagtcgcgttgacctcttcattgacaactccaggaatcagatctccctaaatatgagagatgtgaccgccgcggacacggccgtctattactgcgcgagagaaaacattattcgggagggccttgaccgctggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8975 JY8QFUQ01AF29Y productive (see comment) Homsap IGHV4-61*02 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD5-18*01 F 3 10 7 18 10.7.18 [2.17.38.11] CARVRARSNSHPGHSWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagcagtaGgttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8976 JY8QFUQ01CC1IS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggctcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8977 JY8QFUQ01CCGG2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY# out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaacttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8978 JY8QFUQ01AXGE4 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatggtgatgggactagcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgttgtatttgcaactgagcagtctgagagccgaggacacggctgtgtatttctgtgcaagacccttgagtgggagttccagatcccccagcggctactggggccagggaacccgtggtcaccgtctcctccgcatccccgaccagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8979 JY8QFUQ01AO96R unproductive (see comment) Homsap IGHV3-9*01 F 406 89.22 91/102 nt 87.25 89/102 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 7 X 16 7.X.16 [X.15.11.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) gattcaccttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8980 JY8QFUQ01BM95A unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 819 86.18 187/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8981 JY8QFUQ01CUJ4V No results 8982 JY8QFUQ01DFKC8 productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8983 JY8QFUQ01DGQKI productive (see comment) Homsap IGHV3-7*01 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.37.11] CARTSSREITDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 8984 JY8QFUQ01API5M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8985 JY8QFUQ01CEZIY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 8986 JY8QFUQ01AZJ58 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 91.78 201/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - gcctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 8987 JY8QFUQ01CRTME productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 8988 JY8QFUQ01DT4RC No results 8989 JY8QFUQ01CHMCE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 514 73.0 146/200 nt 8 8 X 8.8.X [2.17.31.X] null - No rearrangement found Low V-REGION identity (73,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtcatcgcctgcctggtccagggcttcttcccca 8990 JY8QFUQ01A4J3A No results 8991 JY8QFUQ01B04S9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8992 JY8QFUQ01DUB3R productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 800 86.05 185/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctgggggCcaccatgagtagtttctactggagctgggttcggcagTcccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 8993 JY8QFUQ01AZBUC unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLPFIVVVTGAFLGHFDY## out-of-frame - ttctggatacacgtttatgaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 8994 JY8QFUQ01DJQ1O unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CANEVGYCSSG# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttaacatgtatgtcatgcactggttccgccaggttccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtgggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8995 JY8QFUQ01BREW3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 8996 JY8QFUQ01BGJXT No results 8997 JY8QFUQ01B793Z unproductive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 X 5 X X.5.X [X.X.38.11] CARDDFYSSGITE#FGMDVW out-of-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcgggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 8998 JY8QFUQ01DRB53 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 8999 JY8QFUQ01A70L0 productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9000 JY8QFUQ01BE4FQ No results 9001 JY8QFUQ01BQ190 productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F 311 85.71 72/84 nt 84.52 71/84 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 X X 20 X.X.20 [X.X.28.11] CAKDIRSVRDRGFSFGYGFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctggattcagagacaacCgccaagaactccctgtatctggaaatgagcagtctgagaantgaggacacggccctgtattattgtgcaaaggatattcgttccgtccgagatcgtggattcagctttgggtacggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9002 JY8QFUQ01CB1XG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9003 JY8QFUQ01AA9ZQ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9004 JY8QFUQ01BB73D productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 714 81.78 175/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (81,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcgcctcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9005 JY8QFUQ01BJASR unproductive Homsap IGHV3-30*10 F (see comment) 712 80.82 177/219 nt 80.37 176/219 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [2.17.38.11] CSRGTTGTTDDSRLFQH## out-of-frame - Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccGcaaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactgggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9006 JY8QFUQ01AFT7Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccagttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9007 JY8QFUQ01CGS2N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9008 JY8QFUQ01BF2UN productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9009 JY8QFUQ01B1W4F productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); agcctctacattcGccctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9010 JY8QFUQ01BGTX0 No results 9011 JY8QFUQ01BNXKI productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 874 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) gcctcctggattcaccCtttggttattatggcatggactggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9012 JY8QFUQ01A0NOK No results 9013 JY8QFUQ01B5RYC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARDGEWELFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtaggtactggatgtactgGggcccgccaagctccagggaAaggggctggtgtgggtctcacgtattaagaatgatgggactaccgcgacctacgcggactccgtggagggccgattcagcatttccagagacaacgccaaggacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattattgtgcacgagatggggagtgggagctatttgactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9014 JY8QFUQ01AJOMR productive (see comment) Homsap IGHV3-11*01 F (see comment) 688 80.09 173/216 nt 79.63 172/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [1.17.37.11] CVRDRSRGIADPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) gtctggattcaccttcactgactattggatgagttgggtgcgcctgaccccagggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaatttagtctttttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 9015 JY8QFUQ01AQMPE unknown (see comment) Homsap IGHV3-7*01 F 1036 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9016 JY8QFUQ01B42GO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9017 JY8QFUQ01DNMAA unproductive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9018 JY8QFUQ01A4MUK productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 858 87.44 195/223 nt 86.55 193/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.16.38.11] CVRAGFGELSGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 21 to 22 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) ccaggcctcctggattcaccCTttgggttattatggcatggactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactactggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9019 JY8QFUQ01CTB18 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9020 JY8QFUQ01CPRY6 productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARHKTISGVVIMGAFDYW in-frame + ctcggaattcacttttggtagtcactggatgagttgggtccgccaggctccagggatgggactggagtgggtggccaacataaaaacagatggaagtgagacacactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcactgtatttgcaagtggacagcctgagagccgaggacacggctgtttattactgtgcgaggcacaaaacaatttctggagtggttattatgggagcatttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9021 JY8QFUQ01CRFXK productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAKHPLRSTSGHSYLDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacatattcaccgacttttatatacactgggtgcgacaggctcctggacaagggcttgagtggatgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcggggcagggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9022 JY8QFUQ01BB3P5 productive Homsap IGHV3-9*01 F 945 93.09 202/217 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD4-17*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARLPGDYGSRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaactttgataaatatgacatgcactgggtccgacaagctccagggaagggcctggagtgggtctcaggtattaagtggaatggcggtcgcgtcggctatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagacctgaggacacggccttctattactgtgcaagactccccggtgactacgggtctcgttggggccagggaaccctcatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9023 JY8QFUQ01CE17F No results 9024 JY8QFUQ01CBGI5 No results 9025 JY8QFUQ01BLWWD productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) tctctggattcacctttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9026 JY8QFUQ01C45JT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 9027 JY8QFUQ01BZOH1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9028 JY8QFUQ01ASH1A unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-9*01 F 3 9 7 X 9.7.X [1.16.38.11] CARILDGYFFD#PG out-of-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctctggtggctccatcgacactcaaattactactggggctggattcgccagccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctgggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactactttccgaaccggtgacggtgtcgtggaactcag 9029 JY8QFUQ01A1IEL No results 9030 JY8QFUQ01BKVBB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9031 JY8QFUQ01CTMCO productive Homsap IGHV3-43*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame + ctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9032 JY8QFUQ01CGZQ8 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 153 53.89 97/180 nt 8 7 X 8.7.X [1.17.26.X] null + No rearrangement found ctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9033 JY8QFUQ01AATLY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.5 206/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9034 JY8QFUQ01C28D8 productive Homsap IGHV1-8*01 F 939 93.46 200/214 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [0.17.38.11] CARGYGYPNYYHYAMDVW in-frame + tggataccccttcgacagttatgatatcagctgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtgggaatacagcctatgcacagaagttccagggccgagtcacgatgaccagggacacctccacaagcacagcctacatggaggtgagcagcctcagatctgaggacacggccgtctattactgtgcgcgcggttatggctacccaaactactaccactacgctatggacgtctggggccaagggttccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9035 JY8QFUQ01CVTSB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9036 JY8QFUQ01BV1VR productive (see comment) Homsap IGHV4-61*02 F 892 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.37.11] CARDPRVICSGGSCRSSAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaaccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 9037 JY8QFUQ01C2XX8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 89.04 195/219 nt Homsap IGHJ4*01 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [2.17.38.11] CVRDRDFLWGSYRLQLEYW in-frame - gactctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaaaaaggggctggagtgggtctcaggaattagtgcgaatggtggtagtataaattatgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacattgtttctgcaaatgaatagcctgagagccgaagacacggccgtatattactgtgtgagagatcgcgatttcctgtgggggagttatcgtcttcaacttgaatattggggccaaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9038 JY8QFUQ01BH3ZC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9039 JY8QFUQ01DWD9J productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [1.17.38.11] CARGGGGKSIPLDNW in-frame - cgtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9040 JY8QFUQ01AN2RA No results 9041 JY8QFUQ01AF5AE No results 9042 JY8QFUQ01AF4Z9 productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9043 JY8QFUQ01CE9R1 No results 9044 JY8QFUQ01DAQCO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttGcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9045 JY8QFUQ01B433C productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9046 JY8QFUQ01AE4R0 No results 9047 JY8QFUQ01DPTXI unproductive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 592 93.94 124/132 nt 93.18 123/132 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 X X 8.X.X [2.3.31.11] WCEGGW*R##LDYW out-of-frame - stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 40 in the user submitted sequence), (do not cause frameshift) acctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactggtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctccagcatccccgaccagccccaaggtcttcccggctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9048 JY8QFUQ01ASZT4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcttggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9049 JY8QFUQ01AXXCO unproductive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 900 90.32 196/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGGGGG#AFDIW out-of-frame + ctctggattcaccttcaggagttatgatatgcactgggtccgccagactccaggcaaggggctggagtgggtggcagtgatattatatgatggaagaaaacaattttacgcagagtccgtggagggccgattcaccatctccagagacaactccgggaacacactggatctgcaaatgaacagcctgagacctgaggacacggctgtctattactgcgcgagagggggaggtgggggtctgcttttgatatttggggccaagggacaagggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9050 JY8QFUQ01AW868 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 687 80.37 172/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARQHFDRGDSGRWLDPW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AW868 ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggctcaccttcacgacttacagcatcacctgggtccgccaggctccggggaagggactggagtggatttcatcaatcagtagcagaggcgagatgatctatggagagtctgtgaagggccggttcaccatctctagagacaacgccactgattcagtgtctctgcagatgaacagtctcagagacgaagacacggctgtgtattattgtgcgagacagcactttgaccgcggtgactccggaaggtggctcgacccctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9051 JY8QFUQ01CZJLE productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9052 JY8QFUQ01ADUHM productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcCccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactca 9053 JY8QFUQ01CRC3J No results 9054 JY8QFUQ01AYGZP productive (see comment) Homsap IGHV1-3*01 F 880 90.61 193/213 nt 89.67 191/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.37.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 133 in the user submitted sequence), (cause frameshift) tggatacagcttcactaactacaatatccattgggtgcgccagGgcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcacatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9055 JY8QFUQ01B1YPU No results 9056 JY8QFUQ01ALL88 productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccCaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9057 JY8QFUQ01BIEJY productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 912 92.06 197/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9058 JY8QFUQ01DVYNM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9059 JY8QFUQ01DMVHW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9060 JY8QFUQ01CEI6I productive (see comment) Homsap IGHV4-39*02 F 947 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9061 JY8QFUQ01CZDGQ productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame + ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 9062 JY8QFUQ01BIEI3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9063 JY8QFUQ01A94FS productive Homsap IGHV3-9*02 F 886 90.28 195/216 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + tccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 9064 JY8QFUQ01BF2YK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9065 JY8QFUQ01BLF36 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 733 82.41 178/216 nt Homsap IGHJ3*01 F 83 62.0 31/50 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDKAGFTLHAFDVX in-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgactttgccagccacgccatggcttgggtccgccggactccaaggaagggcctggagtgggtctcaggcataagtagtagtggtggaaccacgtattacgcagacttcgtgaagggccgcgccactgtctccagagacaattccgagaacacagtgtctctggaactccacagcctgagagccgatgacacggccatatattattgtgtgaaggacaaagcgggcttcaccctccatgcttttgatgtcnggggccgagggacggtgtcactgtttcttcaacatccccgaccagccccaaggctcttcccgctgagcctctgcagcaccctagccagatgggaacgctggtcgatcgccctgcctggnccagggcttcttcccccatgga 9066 JY8QFUQ01BECCF No results 9067 JY8QFUQ01AT6SD productive (see comment) Homsap IGHV4-39*07 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 9 7 15 9.7.15 [1.17.38.11] CARAVLDNAWPIYYDFW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01AT6SD ; 10 AA in Homsap_IGHV4-39*07), and low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcaccacttggcattactggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccCctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9068 JY8QFUQ01CPK0C No results 9069 JY8QFUQ01DDZWF No results 9070 JY8QFUQ01DB3P3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 7 8 18 7.8.18 [2.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) agcctctggattcaccGtttagcagctagccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9071 JY8QFUQ01BX6QP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9072 JY8QFUQ01CEN22 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9073 JY8QFUQ01BNIV0 No results 9074 JY8QFUQ01BIUUG productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1105 100.0 222/222 nt 98.65 219/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.16.37.11] CTKCSVTIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) cttctggattcacctttGggtgattatgctatgagctggttccgccaggctccaggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9075 JY8QFUQ01CN1QR productive (see comment) Homsap IGHV3-72*01 F 956 92.76 205/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.16.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 182 to 182 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 2 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttgcgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatTgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgggagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9076 JY8QFUQ01DBOA7 No results 9077 JY8QFUQ01C0VWU productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 861 87.73 193/220 nt 87.27 192/220 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.16.38.11] CARQRYYESDGQTW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctctggtggctccatcaccggaagtagttattattggggctggattcgccagtcccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 9078 JY8QFUQ01DGH8W unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9079 JY8QFUQ01BAD7L unknown (see comment) Homsap IGHV3-72*01 F 106 53.44 70/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9080 JY8QFUQ01BRJZV No results 9081 JY8QFUQ01DBC2M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9082 JY8QFUQ01C2QO4 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 948 91.93 205/223 nt 91.48 204/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDRRGSDIPPQFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggatttagtttcaataacgcctggatgagctgggtccgccaggctccagggaaggGggctggagtgggttggccgtattaaaagcaaagctgatggtggggcggcagactacggtgcacccgtgagaggcagattcaccatctcaagagatgattcaagaggcacggtgtctctgcaaatgagcagcctgaaaaccgaggacacagccatctattattgtaccacagataggaggggttcggatattccacctcaatttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9083 JY8QFUQ01ASCP3 No results 9084 JY8QFUQ01DV802 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9085 JY8QFUQ01COEXB unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 116 54.14 72/133 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 9086 JY8QFUQ01CD0PS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9087 JY8QFUQ01CHBEX productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9088 JY8QFUQ01DEVGU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 187 86.0 43/50 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgttcctcag 9089 JY8QFUQ01BEW4I unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 912 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 7 8 X 7.8.X [1.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) ctcggattcaccttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggantgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt 9090 JY8QFUQ01BJUQ6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 593 78.06 153/196 nt 77.55 152/196 nt 8 8 X 8.8.X [1.16.31.X] null - No rearrangement found Low V-REGION identity (78,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggcccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9091 JY8QFUQ01B9YJO No results 9092 JY8QFUQ01A8VXJ unproductive Homsap IGHV3-9*01 F 878 89.45 195/218 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARTYGDHD#MDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaggacttacggcgaccatgacgaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9093 JY8QFUQ01AF3VA unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AF3VA ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9094 JY8QFUQ01BMMMW productive Homsap IGHV3-33*04 F (see comment) 703 80.37 176/219 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [2.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcatttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9095 JY8QFUQ01B6ZW6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccaggtgacggtgtcgtggaactc 9096 JY8QFUQ01CGNDO No results 9097 JY8QFUQ01CWXDQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9098 JY8QFUQ01DWBZW No results 9099 JY8QFUQ01CJDMN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 861 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - agcctctggattcacctttaccgcctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9100 JY8QFUQ01A5NLU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctCcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9101 JY8QFUQ01BMH1M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt 86.36 190/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9102 JY8QFUQ01BU44K No results 9103 JY8QFUQ01AU15Y productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 845 88.37 190/215 nt Homsap IGHJ2*01 F 175 81.13 43/53 nt Homsap IGHD3-9*01 F 2 8 7 12 8.7.12 [1.17.38.11] CAREATYYDAFDVW in-frame + tctctggcggctccatcgggagttactactggacctggatccggcagtctccagggaaggggctggagtggattggatatagccacagcagtgggaaaaccaattataatccttccctcaagagtcgagtcaccatatcaatagacacgtccaagaaccagttctccctgcagctgacctctgtgaccgctgcggacacggccatatattcctgtgcgagagaagcaacttactatgatgccttcgatgtctggggccgtggcacccaagtcagtgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9104 JY8QFUQ01A0HOP productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD1-26*01 F 3 10 6 15 10.6.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) ctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 9105 JY8QFUQ01CUTS1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CAREEWDNGGFGAW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgacttcacttactactggatgcactgggtccgccaagttccagggcaggggctcgtgtgggtcgcacgtattgggattgttggtggtaaagcagactacgcggacgccgtaaagggccgtttcaccatctccagagacaacacaaggaagactctgtatctacaaatgaacagtctgcgacccgaggacacggcggtgtattactgtgccagagaggaatgggacaacggtggtttcggggcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 9106 JY8QFUQ01AYAJQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 408 87.62 92/105 nt 86.67 91/105 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 9107 JY8QFUQ01DCOGY No results 9108 JY8QFUQ01CXAIJ productive Homsap IGHV3-11*01 F (see comment) 769 84.26 182/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9109 JY8QFUQ01CXVP1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 864 88.94 193/217 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD3-16*01 F 2 8 8 15 8.8.15 [1.17.38.11] CATQNYEGGAPFWFDPR in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagaaacagtatgaattgggtccgccaggctccagggaaggcgctggagtgggtcgcaggcattagtagtagtggtacttatatagattacgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtctctgcaaatgaacagcctgaggggcgaagacacggcgatttactactgtgcgacccaaaactacgaagggggggctcccttttggttcgaccccaggggccagggaacccgtggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9110 JY8QFUQ01C0FOR unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 172 94.74 36/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcacctttggttattatggcatgagctggg 9111 JY8QFUQ01AJ1VA productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 9112 JY8QFUQ01BDB92 unproductive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKSGTYSSSSGHFDL## out-of-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccaagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9113 JY8QFUQ01DITNB No results 9114 JY8QFUQ01DPMX1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcagtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9115 JY8QFUQ01BYF7R productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 11 8.7.11 [1.17.38.11] CARGPSGSGFDLW in-frame - tctatggtgggtccttcagtggttactactggagctggatccggcagtccccagggaagggactggaatacattgcaactatctatggcagtagaaccaccaactacaacccctccctcaagagtcgagtcaccatatcagtggacacgcccaggaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtattttactgtgcgaggggtccctccgggtccggatttgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9116 JY8QFUQ01C2W90 No results 9117 JY8QFUQ01AGVXF No results 9118 JY8QFUQ01A64VB productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARSYGFSRFDPW in-frame + tctctggtggctccatcaccagtagtctttaccgctggggctggatccgccagtccccagggaagggcctggagtggatagggaatatcttttatggtgggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9119 JY8QFUQ01AKBBL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9120 JY8QFUQ01DB70M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9121 JY8QFUQ01BA1NX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt Homsap IGHJ6*02 F 121 66.13 41/62 nt Homsap IGHD3-22*01 F 2 8 8 27 8.8.27 [1.17.38.11] CARDSDGQTQGDGRGYYYISFYYHGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcatccattagtagtactagtaatcacatattctacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattccgacggacagacgcagggagatggtcgtggttattactacatttccttctactaccacggtatggacgtctggggccaagggtaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 9122 JY8QFUQ01CWR7Q productive (see comment) Homsap IGHV3-48*03 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.16.38.11] CAKDKSAAWYAYFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 53 of V-REGION: 2 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttctcccatgaactgggtccgccaggctccagggaggggcgtggagtggttcatacattagtggtagtggtactaccatgtattacgcagactctgtgcagggccgattcaccgtctccagagacaatgccaagaacttactgtatctgcaaatgaacagcctgagagccgaggacacggctttttattattgtgcgaaagataagagcgctgcctggtatgcctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9123 JY8QFUQ01DE33S productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 947 92.31 204/221 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-19*01 F 1 10 7 10 10.7.10 [1.17.38.11] CAAYDSGWYKHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctggagtggattggatacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtctaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcgtngcatgcctggttccaggggccttcttcccc 9124 JY8QFUQ01CH6U0 unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9125 JY8QFUQ01BRYWA productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 90 to 95 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9126 JY8QFUQ01BK7KR productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9127 JY8QFUQ01BC2IW productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 9128 JY8QFUQ01B530R productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9129 JY8QFUQ01A5TIW unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccttggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9130 JY8QFUQ01BF6VT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9131 JY8QFUQ01CHO3Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9132 JY8QFUQ01AR4BT No results 9133 JY8QFUQ01AC3GP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggGggccggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9134 JY8QFUQ01BNQW6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9135 JY8QFUQ01AMWRD productive (see comment) Homsap IGHV3-30*01 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [2.16.38.11] CAREWAASHFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'AA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) gccgctggattcaccttcagtggctttgcttgcactggctccgccaggctccAAaacaagggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9136 JY8QFUQ01CN0HY productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9137 JY8QFUQ01C8V7V unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1070 97.77 219/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTDGGISS#FDFW out-of-frame - cctctggattcaccttcagtaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgctggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaagaacacgctgtatttgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtaccacagatgggggcatctcgtcccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9138 JY8QFUQ01A6FUM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9139 JY8QFUQ01CYXIA unknown (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 9140 JY8QFUQ01BG50Z No results 9141 JY8QFUQ01CM1E0 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9142 JY8QFUQ01DGV60 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 771 99.36 156/157 nt 98.09 154/157 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 X 8 18 X.8.18 [X.6.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagGaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9143 JY8QFUQ01AD8J3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAGYYPPSSPFDYW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagcggtagtggtgatagcacatactacgcagactccctgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgggagccgaagacacggccgtatatcgctgtgcaggctattatcccccaagtagcccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9144 JY8QFUQ01DSL9S No results 9145 JY8QFUQ01CGMXU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9146 JY8QFUQ01BS1HE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 7 8 10 7.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) ttctggattcactttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9147 JY8QFUQ01CS9KQ productive Homsap IGHV3-72*01 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 10 9 8.10.9 [0.17.38.11] CAVAAPPYDGW in-frame - ctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9148 JY8QFUQ01DQWX2 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F 121 54.48 73/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcacgtttagtgactactacatgacctggattcgtcaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9149 JY8QFUQ01B6N9B unknown (see comment) Homsap IGHV3-48*01 F 968 94.04 205/218 nt 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 94 of V-REGION: 'C' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); tctctggtgggtccttcagtggttacttctggaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcCctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag 9150 JY8QFUQ01APC76 No results 9151 JY8QFUQ01CUB5Z productive (see comment) Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 871 90.14 192/213 nt 89.67 191/213 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); tctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtGgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9152 JY8QFUQ01DEXKU productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 9153 JY8QFUQ01C3IIM productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9154 JY8QFUQ01DAMHL productive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9155 JY8QFUQ01CCKZP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 468 68.2 148/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9156 JY8QFUQ01CA1G6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcaGgcccccaggaaagggactggagtggattgggtatatcCttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 9157 JY8QFUQ01BHYP9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 800 85.25 185/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagttctggatncactggggtccgcaagttccagggagggactggtntgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 9158 JY8QFUQ01AECKB No results 9159 JY8QFUQ01CFKT7 No results 9160 JY8QFUQ01BPU9T No results 9161 JY8QFUQ01BJDXD productive (see comment) Homsap IGHV3-23*05 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 7 18 8.7.18 [2.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 9162 JY8QFUQ01B85GD No results 9163 JY8QFUQ01DSG6M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9164 JY8QFUQ01BTLKF productive (see comment) Homsap IGHV3-48*01 F 979 95.77 204/213 nt 95.31 203/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [0.16.38.11] CAKDGPGGGWYAEQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) tggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggggctgagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccaattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9165 JY8QFUQ01BLRNU unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDLRGSTMASD#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaaggggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 9166 JY8QFUQ01C5HJ8 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggtgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 9167 JY8QFUQ01C9SDI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 698 80.28 175/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9168 JY8QFUQ01A4BFS productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 936 92.63 201/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARGSRDVGDAFDVW in-frame - gtctggattcaccttcactaaccatgtcatgcactgggtccgccaggctccaggcaaggggctggagtggttggcaattatatggtatgatggcagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgattgatctgcaaatggacagcctgagagtcgaagacacggcggtgttttattgtgcgagagggagccgggacgtcggggatgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9169 JY8QFUQ01C5HGU unknown (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9170 JY8QFUQ01A0RJS productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) cctctggattacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9171 JY8QFUQ01CVXL1 No results 9172 JY8QFUQ01DQG9K productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9173 JY8QFUQ01BF2HZ unproductive (see comment) Homsap IGHV3-9*01 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKSGTYSSSSGHFDLW in-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'AG' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) agcctctggattcaacctttaataAGttatgccatgcactggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9174 JY8QFUQ01B1TFE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9175 JY8QFUQ01CPB9D No results 9176 JY8QFUQ01AXV08 unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9177 JY8QFUQ01AXREM productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 9178 JY8QFUQ01CQBLN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [3.17.38.11] CAKAPYGEDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); gcagcctctggattcacctttagcgactatgCccatgaactgggtccgccaggctccagggaaggggctacagtgggtctcatctatcagtgatagtggtggttccacatactccgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctttatctgcgaatgagcagcctgagagccgaggacacggccatatattactgtgcgaaagcaccatacggtgaagatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9179 JY8QFUQ01CWGHM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 9180 JY8QFUQ01ARRSG No results 9181 JY8QFUQ01DVMRY productive (see comment) Homsap IGHV3-11*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 12 8.8.12 [1.16.38.11] CAVDCTSISCNGDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) cctctgggttcaccttcagtgactactacatgagctgatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcggtagattgtactagtatcagctgcaacggagactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9182 JY8QFUQ01CHFYS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 707 80.73 176/218 nt 80.28 175/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARYRVGDSLYYGLDGW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 90 to 92 in the user submitted sequence), (do not cause frameshift); cctctggattcattttagaaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9183 JY8QFUQ01AMX59 productive (see comment) Homsap IGHV3-33*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9184 JY8QFUQ01C6TKI No results 9185 JY8QFUQ01AK8PN productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9186 JY8QFUQ01A0UZS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.91 200/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 1 8 8 12 8.8.12 [2.17.38.11] CGKQLGAHKGADYW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) agcctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccataaaggggctgactactggggccaggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9187 JY8QFUQ01DF0O2 productive Homsap IGHV3-7*01 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDPYKPGSGNPGFDYW in-frame - gcctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9188 JY8QFUQ01DC2T3 No results 9189 JY8QFUQ01B8WF3 productive Homsap IGHV3-72*01 F 975 93.27 208/223 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD4-11*01 ORF 1 8 10 13 8.10.13 [1.17.38.11] CVRGLQSNYYGMDVR in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaaaattaacagttacagtacagaatatgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaatttactgtatctgcaaatgaacagcctgagaagcgaggacacggccgtatattactgtgttagaggcctacagagtaattactacggtatggacgtcaggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9190 JY8QFUQ01BB8SR No results 9191 JY8QFUQ01A6D5Q No results 9192 JY8QFUQ01DJVB1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9193 JY8QFUQ01C6DVK unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 849 88.79 190/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CTRELRMAAARDGVDI## out-of-frame + ctctgggttcgccgtcagtagcaagttcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatcctgatgggactacacactatggagactccgtgaggggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggcccaaggcacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9194 JY8QFUQ01B3WVQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 257 61.96 101/163 nt 61.35 100/163 nt 8 10 X 8.10.X [1.16.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01B3WVQ ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (61,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaagggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9195 JY8QFUQ01AATOF No results 9196 JY8QFUQ01ALFG8 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9197 JY8QFUQ01DLF4V productive (see comment) Homsap IGHV3-7*01 F 747 95.71 156/163 nt 95.09 155/163 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 7 1 11 7.1.11 [X.17.28.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 49 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9198 JY8QFUQ01CYI6J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.37.11] CAKDTITMGGDVAPLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) ctctgggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9199 JY8QFUQ01AHR1C productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9200 JY8QFUQ01CQ6LV productive (see comment) Homsap IGHV4-61*02 F (see comment) 668 78.28 173/221 nt 77.83 172/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHGLSIGGARELDFW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 31 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctctggtggcgccatcaCtgatttttggttccttctggcactggatccgccagcccgccgggggcggactggaatggctcggacgtgtttattataatggggacaccaacctcaatccttccctcaggagtcgactttccatgtcaggagacacgtccaacaaccacttctacctgaggttgaggtctgtgaccgccgaagacacggccacttattattgtgcgagagagcatggtctttcgattggcggagcgagagaacttgacttctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 9201 JY8QFUQ01BRKHB No results 9202 JY8QFUQ01AXACT unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 83 51.54 67/130 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9203 JY8QFUQ01BGFH0 productive Homsap IGHV1-8*01 F 840 88.32 189/214 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-16*01 F 1 8 8 18 8.8.18 [0.17.38.11] CARGLTMGENYHSYYGMDAW in-frame + tggatacacattcacccttcatgatatcaactgggtgcgacaggcccctggacaaggacctgagtggatgggatggatgaacccaaacaacaattacagaggttatgcacagaagttccagggccgagtcaccatgaccagggacaccgccacagccacagcctatctggagctgagcagcctgagatcagatgacacggccgtgtattactgtgcgaggggcctaaccatgggggagaattaccactcctactacggtatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 9204 JY8QFUQ01AUWMR No results 9205 JY8QFUQ01CYGM0 No results 9206 JY8QFUQ01CZNK7 No results 9207 JY8QFUQ01AE027 No results 9208 JY8QFUQ01B8MBE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 9209 JY8QFUQ01AQ0R8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 9210 JY8QFUQ01CPUEG productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9211 JY8QFUQ01AD79A productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9212 JY8QFUQ01AZ1E2 No results 9213 JY8QFUQ01BDD3C No results 9214 JY8QFUQ01BHPNF No results 9215 JY8QFUQ01DWJNN productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDQRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcagcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9216 JY8QFUQ01CK1VY productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 848 87.33 193/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARGGGWTPYFDSW in-frame + tctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattactgtgcgaggggcggtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccccctaagatcgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9217 JY8QFUQ01COZRA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9218 JY8QFUQ01BOOMA No results 9219 JY8QFUQ01CXLBY productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 839 86.88 192/221 nt 85.52 189/221 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.16.38.11] CSRRSTLVTGYVFDKW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) cctctggaatcaactttcgtgatcatgccatgagctgttccgccaggttccaggaaggggctggagtgggtaggttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9220 JY8QFUQ01ARH7H productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9221 JY8QFUQ01DK8VO No results 9222 JY8QFUQ01C1RLY No results 9223 JY8QFUQ01B1K6G productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9224 JY8QFUQ01CKQZV productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9225 JY8QFUQ01BPLD8 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 12 10.7.12 [1.17.37.11] C#RDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift)in CDR3-IMGT, from codon 105 of V-REGION: 1 nucleotides (from position 221 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9226 JY8QFUQ01AWPQF No results 9227 JY8QFUQ01DGYBA productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-33*03 F (see comment) 375 79.34 96/121 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 X 2 17 X.2.17 [X.X.38.11] CAKDTITMGGDVAPLFDYW in-frame + Low V-REGION identity (79,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 9228 JY8QFUQ01B5OFT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttccccca 9229 JY8QFUQ01AKHML No results 9230 JY8QFUQ01BHHX3 productive (see comment) Homsap IGHV3-48*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [2.17.38.11] CVTERGGGLLRYLDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccagggaaggGggctggagtggatttcatatattagtagcagtagtcaaacgatttactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactgtgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9231 JY8QFUQ01A0GUN No results 9232 JY8QFUQ01CGAJV No results 9233 JY8QFUQ01A0ECJ productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 276 81.18 69/85 nt 80.0 68/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcagagacaatgccaggaactctctctacttgcAaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 9234 JY8QFUQ01DSARW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 9235 JY8QFUQ01A9YQH productive (see comment) Homsap IGHV3-7*03 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tcccggattcacttttggtgactattggatgagctgggtccgccaggttccagggaAagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 9236 JY8QFUQ01DCC26 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9237 JY8QFUQ01COZCP No results 9238 JY8QFUQ01CMV5N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtagtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9239 JY8QFUQ01BK4M5 productive Homsap IGHV3-33*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame + gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9240 JY8QFUQ01CV4X4 productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame - tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9241 JY8QFUQ01AA0O7 productive (see comment) Homsap IGHV4-39*02 F 852 87.73 193/220 nt 87.27 192/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.17.38.11] CARQMGYSGSGLSVWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift); ctctggaggctccatcaacactaatcgttactactgggtctggtttcgccagccccccgggGAagggggctggagtggattgggactatttattatactgggatcaccaactacaatccattcttcaagagtcgagtcaccatgtccgtagacacgtccagccaccacttctccctgaggttgagctctgtgaccgccgcagacacggctgtctactactgtgcgagacaaatgggatactctggttcggggctcagtgtgtggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9242 JY8QFUQ01AGOHV unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 917 90.18 202/224 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNRCWPTLVLLRYGRFG# out-of-frame + tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagagaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9243 JY8QFUQ01CR4KY productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9244 JY8QFUQ01C8XI8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cttctggattcacctttggtgattatgctatgagctgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9245 JY8QFUQ01CCN84 productive (see comment) Homsap IGHV4-55*03 P (see comment) 739 82.11 179/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [2.17.38.11] CARDQSVYTAGSYFDSW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); gtctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattgGgggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaatcaattctccCctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9246 JY8QFUQ01DFWVC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [2.17.38.11] CMNELGYCSGG# out-of-frame - in FR3-IMGT at codon 74 of V-REGION: 'GG' (2 nucleotides at position 127 to 128 in the user submitted sequence), (cause frameshift); gcctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaagGGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9247 JY8QFUQ01CXWID productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9248 JY8QFUQ01BDFG6 unproductive (see comment) Homsap IGHV4-61*02 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD3-10*01 F 1 8 7 17 8.7.17 [1.17.38.11] CARDPPFGELGWGRF*CFG in-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'GGAAAAC' (7 nucleotides at position 24 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaggcgtGGAAAACtattactggagttggcttcggcagcccgccgggaagggattggagtggaTttgggagtttgtatagaggtgggagcaacagctacaatccgtccctcaagagtcgagtcggcatatcagcggacacgtccaggaaccgattctccctgacggtgacttctgtgaccgccgcagacacggccgtgtattactgtgcgagagaccccccatttggggaattgggatggggcaggttttgatgttttgggggccaaggggcaacggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9249 JY8QFUQ01C3Y4I No results 9250 JY8QFUQ01AIN7Q productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 9251 JY8QFUQ01ADIL3 No results 9252 JY8QFUQ01CE93I unknown (see comment) Homsap IGHV2-5*03 F 177 54.69 105/192 nt 10 7 X 10.7.X [9.17.26.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9253 JY8QFUQ01CB3GX No results 9254 JY8QFUQ01DF6EI No results 9255 JY8QFUQ01AFHD7 No results 9256 JY8QFUQ01A03VN No results 9257 JY8QFUQ01BNODT productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctgaagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9258 JY8QFUQ01A1VKQ unproductive Homsap IGHV4-61*02 F 978 94.09 207/220 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARVRARSNSHPGHSWFD#PW out-of-frame + ctctggtggctccatcagcagcagtagttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggcaactca 9259 JY8QFUQ01CLZ8J productive (see comment) Homsap IGHV4-61*02 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [2.16.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) tgtctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaaggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9260 JY8QFUQ01BM8FO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9261 JY8QFUQ01BNLGB No results 9262 JY8QFUQ01DKBP6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9263 JY8QFUQ01CZ986 No results 9264 JY8QFUQ01AB54F unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca 9265 JY8QFUQ01DNPWY unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9266 JY8QFUQ01AJZW6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtggggggggaccaggggaccctggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9267 JY8QFUQ01BXREE productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 25 10.7.25 [1.17.38.11] CAREYPSDRDSSDSSGYLPTSGPLDYW in-frame + tctctggtggctccatcagcagaggtaattactactggacgtggatccggcagcccgccgggacgggactggagtggattgggcgtatctatcccagtgggagaaccaactacagcccctccctcaagagtcgcgtcaccatatcagcagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttgtattactgtgcgagagagtacccctcggacagagattcctctgatagtagtggttatcttcccacctccgggccccttgactactggggcctgggaatccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9268 JY8QFUQ01B5HQ5 No results 9269 JY8QFUQ01AKUDL productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + tctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9270 JY8QFUQ01C00T0 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame + tctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccanccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9271 JY8QFUQ01BVUQP unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPHFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9272 JY8QFUQ01DSA91 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 652 77.78 168/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagcgactatggcatgacctgggtccgccaggctccagggagggggttggagtgggtcgcatctattaatgccggtggtagtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9273 JY8QFUQ01DCXV4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD1-1*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAREPGRGYTPAMNWYFDLW in-frame + ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgagagagcctgggaggggttatacacctgcaatgaactggtacttcgatctctggggccgcggcaccctggtcactgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9274 JY8QFUQ01DI94G unproductive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9275 JY8QFUQ01CMIQ2 productive (see comment) Homsap IGHV1-2*02 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.37.11] CAKHPLRSTSGHSYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) tggatacatattcaccgAccttttatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcgggcagggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9276 JY8QFUQ01BM71Y productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9277 JY8QFUQ01BL2HM No results 9278 JY8QFUQ01CCEOF No results 9279 JY8QFUQ01CPVC8 productive (see comment) Homsap IGHV3-7*01 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSRSPANW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'T' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); ctctggattcagttttagtacctattggatgagctgggtccgccaggctccagggaaggggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaatTtcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 9280 JY8QFUQ01DMIN3 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9281 JY8QFUQ01B3C79 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 702 80.65 175/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRVPTQWFPTLPH##FDIW out-of-frame + stop codons Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaagggcctggaatgggtctctgctatcagtggcagcgatgatcgcacatcttatgttgactccgtgaagggccgcttcaccatctccagagacacttccaggaatacactgtttctgcagatgaacagcctgagcgccgaagatacggccacatacttttgtgtgagagtccccactcagtggtttcccacccttccacactcactttgacatctggggccagggaaccgtggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9282 JY8QFUQ01ASIMC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccCagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9283 JY8QFUQ01DC0FL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.16.38.11] CAKDAITMGGDVAPLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) acctctgggattcacctttagtaactatgacatgggctgggtccgccagctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacgccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9284 JY8QFUQ01ACT0R unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 9285 JY8QFUQ01A30DY unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [1.17.38.11] CARAPGWMNPFDF## out-of-frame + ctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggccactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga 9286 JY8QFUQ01B6LVM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 873 89.4 194/217 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD6-25*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGRGQQREDAFDIW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcatcttcagtagttatagtttgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatatgagtagttcttacatctattatggagactcagtgaggggccgatttaccatctccagagacaacgccgagagctcactgtatctgcagatgagcagcctgagagccgaggacacggctttatattattgtgtgagaggcgggagggggcagcagcgagaagatgcttttgacatttggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9287 JY8QFUQ01CNJXB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9288 JY8QFUQ01B0KN7 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9289 JY8QFUQ01BPY8F unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P 433 85.0 102/120 nt Homsap IGHJ3*02 F 79 62.0 31/50 nt X 2 X X.2.X [X.X.38.11] CVRDLAARPPYYYYGMDV (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION tctggattcaccttcaactcagtgaagggccgattcaccatctccagagacgactccaagaactcactgtttctgcagatgaacagcctcagagccgaggacacggctgtttattattgtgtgagggatttggcggctcgtcccccttattattactacggtatggacgtctgggccaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttccccc 9290 JY8QFUQ01DOGII productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 703 80.37 176/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARGLGLNAVYAFDVW in-frame - Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) gcctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9291 JY8QFUQ01BW0XF unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgaaccggtgacggtgtcgtggaactcag 9292 JY8QFUQ01AIAIG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacac 9293 JY8QFUQ01DTRO5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-7*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKVFQVPGEHHFYYFGMNVW in-frame - cctctggattcatgtttaggaactatgccatgagttgggtccgccaggctccagggagggggctggagtgggtctcaactattagcaataatggaagccacacatactacgcagactccgtcaagggccggttcaccatctccagagacaattccaagaacacggtgtatatgcagatgaacaggctgagagtcgaggagacggccctgtactactgtgcgaaagtcttccaggtgcctggcgagcaccacttctactacttcggaatgaatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagga 9294 JY8QFUQ01BULWY productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagcactacttccccgaaccggtgacggtgtcgtggaactcag 9295 JY8QFUQ01BKNFK productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtcatctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 9296 JY8QFUQ01CDABH productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9297 JY8QFUQ01CJKSZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [2.17.38.11] CARDILGATRFDYW in-frame - gcctctggattcaccttcagcagctatgccatgagctgggtccgccaggctccagggaagggcctggagtgggtctcagctattagtggtattggtgggagtacattctacgcagactccgtgaagggccggttcaccatcaccagagacaattccaacaacacgctgtttctgcaaatgaatagcctgagagccgaggacacggccatatattactgtgcgagagatattctgggagctactcggtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9298 JY8QFUQ01AHEUW unproductive Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDGLL# out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtgggtttttactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9299 JY8QFUQ01DCEET productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - tctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9300 JY8QFUQ01B0TW5 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9301 JY8QFUQ01CL6RH productive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9302 JY8QFUQ01CO333 No results 9303 JY8QFUQ01B95LP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9304 JY8QFUQ01AGV8A productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gctgggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9305 JY8QFUQ01C465V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcaatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9306 JY8QFUQ01DO8CH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 665 90.62 145/160 nt 90.0 144/160 nt 8 8 X 8.8.X [1.17.19.X] null + No rearrangement found in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaac 9307 JY8QFUQ01B8NC5 No results 9308 JY8QFUQ01C1FIH productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9309 JY8QFUQ01DWOEW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFDPL# out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9310 JY8QFUQ01BCYMS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 9311 JY8QFUQ01B5XDW productive Homsap IGHV3-30*01 F 945 93.09 202/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactgggggccagggaaccctggtcacgtctccctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9312 JY8QFUQ01AV4FN No results 9313 JY8QFUQ01AU5BH No results 9314 JY8QFUQ01A3C8Q productive (see comment) Homsap IGHV3-74*03 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAKVDSDGWHGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtaAgttactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9315 JY8QFUQ01CEK5G unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 814 97.65 166/170 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found ctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc 9316 JY8QFUQ01BOXSC productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatcccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccc 9317 JY8QFUQ01CE1W3 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 925 90.99 202/222 nt 90.54 201/222 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 10 22 8.10.22 [1.17.38.11] CATDRPYYKNAAGRLWYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgAaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9318 JY8QFUQ01BSL07 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9319 JY8QFUQ01A721G No results 9320 JY8QFUQ01DFNKY productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9321 JY8QFUQ01DGB8B No results 9322 JY8QFUQ01DIZY8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDLNGGTT# out-of-frame + ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgagagatcttaacggggggactactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9323 JY8QFUQ01AUXRB No results 9324 JY8QFUQ01BSDG9 No results 9325 JY8QFUQ01AU79L productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [2.17.38.11] CARASTLRYLDRW in-frame - gtctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9326 JY8QFUQ01BWHRN productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 925 90.99 202/222 nt 90.54 201/222 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.16.38.11] CTTAPSETYATEYFAMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctgaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9327 JY8QFUQ01CD99S productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - ctctggtttcacatttagtacgtactggatgagttgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9328 JY8QFUQ01B45SQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 651 99.25 132/133 nt 98.5 131/133 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 X 18 8.X.18 [1.11.24.11] CAKFMGVVVVPAAHNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 84 nucleotides (from position 62 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9329 JY8QFUQ01CN4ZQ unproductive Homsap IGHV3-66*02 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) agcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9330 JY8QFUQ01CWIYB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRVVLMVHAMS#DFW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); tctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcgggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9331 JY8QFUQ01B60M1 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatnggtcttcccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9332 JY8QFUQ01DMKKA productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9333 JY8QFUQ01BNTGV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9334 JY8QFUQ01C11GP productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1016 97.21 209/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagaaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9335 JY8QFUQ01CSP5B No results 9336 JY8QFUQ01CQSBL productive (see comment) Homsap IGHV4-61*02 F 875 90.57 192/212 nt 89.62 190/212 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [0.17.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); ccggtggctccatcagtaCTGGTTattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9337 JY8QFUQ01DQHIB productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CVKDLGSYGSPWRAYYYYGMDAW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggattcGaccctcaacagcCaatggcatgcactgggtccgccagactccagacaaggggctggagtgggtggcagtgatttcatatgatggaaatgataaatactatggagatgcagtgacgggccgattcaccatctccagagacacttccaagaacacagtatatctggagatgtacagcctgagacctgaggacacggctgtgtattactgtgtgaaagatcttgggagttacggtagtccttggcgcgcctactattactacggcatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 9338 JY8QFUQ01DCUZM No results 9339 JY8QFUQ01CW3H6 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ4*03 F (see comment) 26 62.5 10/16 nt 8 8 X 8.8.X [1.17.38.0] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataatttacggtgactantgggggacccaggggaaacccccgttgggctcaccgtctcctcagcatcccctgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaatg 9340 JY8QFUQ01AFE6A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9341 JY8QFUQ01CCLHR productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 9342 JY8QFUQ01DG5UT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9343 JY8QFUQ01BGA3A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 9344 JY8QFUQ01AJ082 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccCaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9345 JY8QFUQ01DR0I6 productive (see comment) Homsap IGHV2-5*02 F 1111 95.47 232/243 nt 95.06 231/243 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.37.11] CAHIRAELSTSCHAFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 182 in the user submitted sequence), (cause frameshift) gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcacttgtttattgggatgatgataagcgctacagctcatctctgaagagcagactcaccatcaccaaggacacctccaaaaccaggtggtccttacaatgactaacatggaccctatggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9346 JY8QFUQ01BOT1H productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); gtctggattcaactcaatagcttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaAatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9347 JY8QFUQ01DTDAG productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gtctggattcGaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9348 JY8QFUQ01ANSN0 No results 9349 JY8QFUQ01AK94Y unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 46 90.91 10/11 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found ctctggattta 9350 JY8QFUQ01BIIIJ productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 9351 JY8QFUQ01DD9VI unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYF#EFW out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactggggcCtggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttggaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttcccccag 9352 JY8QFUQ01CIG6T productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.37.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgaggtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9353 JY8QFUQ01A7QC0 productive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9354 JY8QFUQ01DN38T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcatcgcctgccctggtccagggcttcttcccccgag 9355 JY8QFUQ01AFMIM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaatacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9356 JY8QFUQ01BZ8RH productive (see comment) Homsap IGHV3-7*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgCcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9357 JY8QFUQ01A75AZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9358 JY8QFUQ01ANOAD No results 9359 JY8QFUQ01B5JBG No results 9360 JY8QFUQ01AVOVU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 98.56 205/208 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame + caactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9361 JY8QFUQ01AQD2V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9362 JY8QFUQ01C8R7N productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9363 JY8QFUQ01B47VP No results 9364 JY8QFUQ01DJ7FP No results 9365 JY8QFUQ01BLGB2 productive Homsap IGHV1-8*01 F 1038 98.6 211/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + tggatacaccttcaccaattatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtggtaacacaccctatgcacagaagttccagggcagagtcaccatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 9366 JY8QFUQ01DRGC4 No results 9367 JY8QFUQ01BJ9SU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaactcag 9368 JY8QFUQ01AXXHP productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1056 99.53 213/214 nt Homsap IGHJ6*02 F 310 100.0 62/62 nt Homsap IGHD5-18*01 F 3 8 8 17 8.8.17 [0.17.38.11] CARPRGYSNYYYYYGMDVW in-frame + tggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggagatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgaggccccgtggatacagcaattactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagggagtgcatccgccccaaccc 9369 JY8QFUQ01B1U6L productive (see comment) Homsap IGHV3-74*03 F 900 90.78 197/217 nt 89.86 195/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-20*01 F 3 8 8 14 8.8.14 [1.17.38.11] CVREKSSNWNRWFDTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CA' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagccactggatgcactggGgtccgccaaggtataggggaggggctgggtgtggCAttgcacgtattaacagtgatggcagtagtacagcttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaagacgctttatctgcaaatgaacagtctgagagtcgaggacacggctgtctattactgtgtaagagagaaaagtagtaattggaaccgctggttcgacacctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacatggtcgtcgcatgcctggtccagggcttcttccccca 9370 JY8QFUQ01DWK39 No results 9371 JY8QFUQ01C5EGC No results 9372 JY8QFUQ01CG58I productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9373 JY8QFUQ01BTW6P No results 9374 JY8QFUQ01DAX5H unproductive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9375 JY8QFUQ01A06W8 No results 9376 JY8QFUQ01AO6XS No results 9377 JY8QFUQ01A95GG No results 9378 JY8QFUQ01BX599 No results 9379 JY8QFUQ01C0RN1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 9380 JY8QFUQ01A44VT unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAGGRGWLIDY# out-of-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactgggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9381 JY8QFUQ01C07DV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKSIIIRGLI#YNFDYW out-of-frame + ctctggatttacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtcc 9382 JY8QFUQ01BG9FB No results 9383 JY8QFUQ01DXF3F No results 9384 JY8QFUQ01CIUPL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9385 JY8QFUQ01A5NL9 productive (see comment) Homsap IGHV1-3*01 F 840 88.32 189/214 nt 87.38 187/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); tggatacagcttcactaatcacattatccattgggtgcgccaGggcccccggacaagggcttgagtgggtggGggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9386 JY8QFUQ01BCHGI unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 80 51.13 68/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcacctttaacctctatgtcatgcactggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9387 JY8QFUQ01BHZ2A No results 9388 JY8QFUQ01BHT2Y productive Homsap IGHV3-53*04 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGNFDLW in-frame - tctcggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttatttctgtgcgagacagactgccccctttgggaactttgacttatggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9389 JY8QFUQ01BJH31 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaagtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9390 JY8QFUQ01B90A3 No results 9391 JY8QFUQ01DWCOM No results 9392 JY8QFUQ01B4PEO No results 9393 JY8QFUQ01BXPNK No results 9394 JY8QFUQ01B2QGE No results 9395 JY8QFUQ01B22NV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9396 JY8QFUQ01AGQWQ productive (see comment) Homsap IGHV3-69-1*02 P 920 92.92 197/212 nt 92.45 196/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 7 10 8.7.10 [1.16.38.11] CARDDKWAFDYW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 78 in the user submitted sequence), (do not cause frameshift) tctctggattcaccttcagtgactacagcatgaactgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9397 JY8QFUQ01BX1DY productive (see comment) Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVRGSSGRFDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagaaaatatgctatgcactgggtccgccaggctccaggcaaggggctggaatgggtggcgattatatcctatgatggaagaagtccatactacgcagactccgtgaggggccgattcaccatctccagagacaattccaggagtactctggatctgcagatgaacagcctgagacctgaggacacggctgtatattcctgtgtgagaggaagcagtggccgctttgactcctggggcccgggaacgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9398 JY8QFUQ01C4ODX unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 778 92.74 166/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattga 9399 JY8QFUQ01AFKGR unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 82 90.0 18/20 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found tctggattcactgtcaataa 9400 JY8QFUQ01ALMB4 No results 9401 JY8QFUQ01BHE7H No results 9402 JY8QFUQ01A1158 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 9403 JY8QFUQ01CTINS No results 9404 JY8QFUQ01AF7NW unknown (see comment) Homsap IGHV3-71*01 P, or Homsap IGHV3-71*02 P 131 52.49 95/181 nt 8 6 X 8.6.X [1.17.28.X] null - No rearrangement found ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtcctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccgaccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9405 JY8QFUQ01CDSV8 No results 9406 JY8QFUQ01B4WKB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1005 95.45 210/220 nt 95.0 209/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); ggcctctggattcagcttGcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9407 JY8QFUQ01BCE04 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9408 JY8QFUQ01BEO43 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9409 JY8QFUQ01CE1WF No results 9410 JY8QFUQ01BDZT5 No results 9411 JY8QFUQ01A3SEN No results 9412 JY8QFUQ01AARD4 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1003 96.3 208/216 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD6-6*01 F 1 8 7 17 8.7.17 [2.17.38.11] CAKGDSSSSKYYYYGMDVW in-frame - gcctctgggttcagcgtcagtatcaactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagcacacactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccttgtatcttcaaatgaacaacctgagagccgacgacacggccgtgtattactgtgcgaaaggtgatagcagctcgtccaaatactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9413 JY8QFUQ01C3Q4U productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1062 96.9 219/226 nt 96.02 217/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); taccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtGccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgGaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9414 JY8QFUQ01C0IDN unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 127 69.64 39/56 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttcccca 9415 JY8QFUQ01BH0LW productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt 81.18 69/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcagagacaatgccaggaactccctctacttgcAaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9416 JY8QFUQ01AJM01 No results 9417 JY8QFUQ01BABC7 unproductive Homsap IGHV1-3*01 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [0.17.38.11] CARDGYRSGNG#DYW out-of-frame - tgggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacgggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 9418 JY8QFUQ01C85JY unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.16.38.11] CARGAPFS**C in-frame + stop codons in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9419 JY8QFUQ01DPTPU No results 9420 JY8QFUQ01DUJ85 No results 9421 JY8QFUQ01A208J productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 937 92.24 202/219 nt 90.87 199/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDGGSYNRMDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'G' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); gcgtctggattcaccttcagtagctatgGgcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtGgaaatatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaaGttccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 9422 JY8QFUQ01CJ7WY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaAaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9423 JY8QFUQ01DBYFF No results 9424 JY8QFUQ01A0X34 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 482 89.92 107/119 nt 89.08 106/119 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 X X 8.X.X [1.14.16.11] CARDFLAPNRFRSV##YYYYGMDVW out-of-frame + stop codons in FR2-IMGT, from codon 53 of V-REGION: 105 nucleotides (from position 72 in the user submitted sequence), (do not cause frameshift) cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggtctggaatggttggcaatgatatgcctgagagtcgaggacacggctgtctattactgtgcgagggatttcttagccccgaatcgttttcggagtgtttgactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 9425 JY8QFUQ01CI7ES productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [2.16.38.11] CVVQILGATIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9426 JY8QFUQ01ANECI unproductive Homsap IGHV3-21*04 F 633 94.37 134/142 nt 93.66 133/142 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 102 66.67 34/51 nt Homsap IGHD6-13*01 F 1 8 X X 8.X.X [1.2.35.11] CARAVSHQVDV## out-of-frame - Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ2*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) cctctggattcgacttcagtagatatatcatgaattggactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaagggggccacggtcaccgtctcctcagcatccccgatcagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9427 JY8QFUQ01AA90J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9428 JY8QFUQ01CI8OX unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 9429 JY8QFUQ01BLI3C productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + gtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9430 JY8QFUQ01BC44E unproductive (see comment) Homsap IGHV4-61*08 F 884 89.14 197/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggtgcctccatcagcagtagtggtcactactggagttggatccggcagcccccagggaagggactggaattcattggaaaaatctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatttcagtggacacgtccgagaaccagttctccctgagcctgaggtctgtgaccgctgcggacacggccctttattactgtacgagggggggtatacacttatgacagcccgtggggccaggggcattcaggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9431 JY8QFUQ01B0NL2 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9432 JY8QFUQ01BDPBH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9433 JY8QFUQ01DOF76 No results 9434 JY8QFUQ01CEVZ4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDSW# out-of-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttgggggcctggggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9435 JY8QFUQ01C32QR unknown (see comment) Homsap IGHV3-64*03 F, or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 184 59.7 80/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttcccc 9436 JY8QFUQ01ADBXZ unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.16.38.11] CVRGDYGGAPRTLLRP#YGLDVW out-of-frame + in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccaggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccaggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctctaagagcacctctgggggccacagcggccctgggctgcctgggtcaaagggactactttgccccgaaccggtgacggtgtcgtggaactca 9437 JY8QFUQ01ANLRW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9438 JY8QFUQ01CC1JT productive Homsap IGHV3-64*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVTCGDYSYEYW in-frame - ctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9439 JY8QFUQ01ALGU6 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9440 JY8QFUQ01BFGBW unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggaacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9441 JY8QFUQ01AJP8I unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1009 95.89 210/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CVRGDYGGAPDITTT#YGLDVW out-of-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9442 JY8QFUQ01DS9GC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 9443 JY8QFUQ01BKBNA productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.16.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagctcccattggatgaactgggtccgccagactccagggaagggctggagtgggtggccaacataaaggaagatggaagtgTggaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9444 JY8QFUQ01BHZ4Z productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccatggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagtggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 9445 JY8QFUQ01CDSCT productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P (see comment) 357 75.38 98/130 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 X 5 13 X.5.13 [X.X.38.11] CATSPSDFDRRWGYW in-frame + Low V-REGION identity (75,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatttagctttagaaccttttggatgagctggggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9446 JY8QFUQ01BBIKE productive Homsap IGHV3-9*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame - cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9447 JY8QFUQ01BFIR7 No results 9448 JY8QFUQ01A3ZJ5 productive Homsap IGHV3-33*03 F (see comment) 761 83.49 182/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CARDRQSWGIDSW in-frame + Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cgtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaattacctacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9449 JY8QFUQ01BSZIQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacggtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 9450 JY8QFUQ01AVH1O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVVQILGATIDYW in-frame + ctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9451 JY8QFUQ01B1YE0 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [1.17.38.11] CASLARGDGRDYW in-frame + gtctggattctactttaataatttttggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaagtgcgaaagagtatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaaaaactcactgtttctgcaaatggacagcctgagagtcgaggacacggctgtttattactgtgcgagcttggcacggggagacgggagggactactggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 9452 JY8QFUQ01C1A12 productive (see comment) Homsap IGHV3-48*01 F 1004 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [2.16.38.11] CRGDPTQRDYG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctgggttcaccttcagtagttatagcatgaactgggtccgccaggctccaggaaggggctggagtggctttcattcattactagtagtggtagtaccgtatactacgcagactctgtgaagggccgattcaccatctctagagacaatgtcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgccgcggtgaccctactcaacgtgactacgggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9453 JY8QFUQ01DNK8N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9454 JY8QFUQ01BBDN7 No results 9455 JY8QFUQ01A6QVX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9456 JY8QFUQ01DML0H unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 884 91.04 193/212 nt 88.21 187/212 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-21*01 F 3 8 7 X 8.7.X [2.16.36.11] CVRGGVSGAFRWGLDY# out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'TG' (2 nucleotides at position 83 to 84 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 2 nucleotides (from position 83 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 91 of V-REGION: 2 nucleotides (from position 174 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 204 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgaatTGatagttctgcgaatctcatcaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaatgacagtctgagagccgacgacacggctgttactactgtgtgagagggggagtcagtggggccttcaggtggggtttggactactgggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9457 JY8QFUQ01AJUSF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD6-25*01 F 1 8 8 22 8.8.22 [1.17.38.11] CARYQGDTSGYQDVFYAHYGMDVW in-frame - Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttaggggctactggatgcactgggtccgtcaggttccaggtaaggcgccggagtggctcgcacgtctgaatactgatggagatagtacaagttatgcggactccgtgaagggccgcttcaccatctccagagacaacgccaggagcacattgttcctgcaaatgagcagtctgagagtcgaagacacggccatttattactgtgcacggtatcagggcgataccagtggctaccaggacgttttctacgcccactacggtatggacgtctggggccaagggacctcggtcaccgtctattcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9458 JY8QFUQ01BHMYN unproductive (see comment) Homsap IGHV4-4*07 F 868 89.35 193/216 nt 87.5 189/216 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD3-16*01 F 3 8 7 10 8.7.10 [2.17.38.11] CARDSGGL*LLG in-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'T' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'A' (1 nucleotides at position 208 to 208 in the user submitted sequence), (cause frameshift); gtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtcCcaaaccagtgggagCcccccactacaacccctTccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccActttttttctgtgcgagagactccgggggactttgactactgggggccccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9459 JY8QFUQ01CTUZY productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag 9460 JY8QFUQ01B5UYP productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 9461 JY8QFUQ01BNE4W productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaggtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9462 JY8QFUQ01ARAFR productive (see comment) Homsap IGHV3-48*02 F 869 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASGGVTEAHYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 100 of V-REGION: 'GG' (2 nucleotides at position 204 to 205 in the user submitted sequence), (cause frameshift); cctctggattcagctccagtgaatataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaggggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgGGgtgttttattactgcgcgagcggaggggtgacagaggctcactactggggccagggaaccctggtcaccgtctcgtcagcatccccggaccagcccccaagggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9463 JY8QFUQ01BHSSH No results 9464 JY8QFUQ01BT7B7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9465 JY8QFUQ01CXX81 unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgagGgacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9466 JY8QFUQ01DFXSD productive Homsap IGHV4-61*02 F (see comment) 649 77.63 170/219 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARGHSGSTGGARQLDSW in-frame + Low V-REGION identity (77,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggtggccccttcagtagttatttctacctctggcactgggtccggcagcccgccggaaagggactggagtggatcggacacactttcagtaatggggccatcacctacaatgccgctctcaagggtcgagtcgccatgttagtggacgtgtccaagagacagttctccctgaggttggcctctgtgaccgccgcagacacggccatatattattgtgcgaggggacatagcgggtcgactggcggagcgagacaacttgactcctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 9467 JY8QFUQ01ARSP1 productive (see comment) Homsap IGHV3-48*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'GGGGGG' (6 nucleotides at position 65 to 70 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctgGGGGGGgagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9468 JY8QFUQ01ADWZ0 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARVGGTEEFAGMLELDYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gtctggattcagtttcagtagctttggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatctggtatgatggaactaataaatattatgcagactccgtgaagggccgattcaccatctcgagagacaattccaagaacacactgtttctgctcatggacagcctgacagccgacgacacggctgtctattactgtgcgagagtcgggggaaccgaggagttcgctggtatgttggaacttgactactggggccaggggaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9469 JY8QFUQ01AQH9S No results 9470 JY8QFUQ01BYYS7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F (see comment) 132 75.0 36/48 nt Homsap IGHD6-13*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSSGG in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtggggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9471 JY8QFUQ01AKHTH productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1001 95.02 210/221 nt 94.57 209/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARMPRGETGYGDDNNYFDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); tctctggtgactccatcaacaggggtggttattTtctggagctggatccgccagcacccagggaagggcctggtgtggattgggtacatctattacagggggagcacctactacaacccgtccctcaagagtcgagttaccatatcaatagacacgtctaagaaccagttctccctgaggctgagctctatcactgccgcggacacggccgtgtattactgtgcgaggatgccccgtggagagactggctacggggatgataataattacttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9472 JY8QFUQ01ARYPI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattaatggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9473 JY8QFUQ01BFE8S productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARSVSLNRGAYFDCW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'T' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagcagctatgccctgagctgggtccgccaggctccagggaaggggctcgaatgggtctcagctgttggcggtggcggtagtaacacatactatgcagactccgtgaagGggccggttcaccatctccagagacaaTttccaagaacacactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatttctgtgcgagatccgttagtctgaatcggggagcttactttgactgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9474 JY8QFUQ01BLXGN No results 9475 JY8QFUQ01BXD9T unproductive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARQRGGGDRQWAFEN# out-of-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaaccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 9476 JY8QFUQ01CUPTB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctccgggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9477 JY8QFUQ01AKKH7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9478 JY8QFUQ01C319O productive Homsap IGHV4-4*07 F 808 86.85 185/213 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9479 JY8QFUQ01BF115 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 103 62.9 39/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9480 JY8QFUQ01BG8O8 No results 9481 JY8QFUQ01CUIH8 unproductive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD6-6*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGSSKS#YNWFDPW out-of-frame - ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtccaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9482 JY8QFUQ01A86BJ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 945 93.09 202/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTGQWKDFDY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaacacgggggggactaacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9483 JY8QFUQ01B580Q No results 9484 JY8QFUQ01DADF3 productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9485 JY8QFUQ01CFS8F unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 946 92.27 203/220 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD1-26*01 F 3 10 7 X 10.7.X [1.17.38.11] CARQLEEGREVLQWNDA#FAIW out-of-frame - ctctggtggctccataagtagtagtagacactattgggggtggatccgccagcccccagggaagggactggagtggattggcagtatgtattatagtggggacacctactacaatccgtccctcaagagtcgagtcgccatatccgcagacacgtccaagaaccggttntccctgaagctgagctctctgaccgccgcagacacggctgtgtattactgtgcgaggcagcttgaggaggggcgggaggtactacaatggaatgatgctttttgctatctggggccaggggacagtggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9486 JY8QFUQ01BNPV4 No results 9487 JY8QFUQ01DPOR8 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9488 JY8QFUQ01BVEWH unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 9489 JY8QFUQ01AOTCJ productive Homsap IGHV3-30*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + ctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9490 JY8QFUQ01C9EZR No results 9491 JY8QFUQ01BX9KN No results 9492 JY8QFUQ01B5VDA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 535 92.06 116/126 nt 91.27 115/126 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-20*01 F 2 8 X X 8.X.X [1.6.26.11] CANASPRITGTYFYYYGY#DVW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacgggtatggacgtctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9493 JY8QFUQ01DHT6B unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CGKPIVGATGREMPVS## out-of-frame + cctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9494 JY8QFUQ01A4M2H unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRVGAPYYDFWSGYQTNWFD#PW out-of-frame + cgtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgaccccgtggggccagggaactctggtcaccgttacctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9495 JY8QFUQ01BFYZZ unproductive Homsap IGHV3-66*02 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcaatagcagcttcatgacttgggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9496 JY8QFUQ01CSDKO productive Homsap IGHV4-39*03 F 919 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9497 JY8QFUQ01BPYWA No results 9498 JY8QFUQ01DHWO6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9499 JY8QFUQ01A90FM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGSYRLQLESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagctatggcatgagttgggtccgccagtctccaaataagggactggagtgggtcgcaggcattagtgcaaatggtggcagtataaattatctggacgccgtgaagggccggtttatcatctctagagacaattccaagaacacgttgtatctgcaaatggacagcctgacagtcgaggacacggccgtttattactgtgtgaaagatcgtgattttctttgggggagctatcgtcttcaacttgaatcttggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9500 JY8QFUQ01DWTCH No results 9501 JY8QFUQ01DQ6K4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 787 85.19 184/216 nt 84.72 183/216 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-2*02 F 1 8 8 19 8.8.19 [1.17.38.11] CARDGSPHSPIYHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctggattcagcttcggtagtcatgttatgaactTgggtccgccaggctcccggaaagggcctggagtgggtcgcaacaattggaacaagaagtaagtctatatattacgcagactcagtgaagggccgatgcaccatatccagagagaacgcccataactcaatgtatctgcaactgaacagcctgacagccgaggacacggctgtttattactgtgcgagagacggcagtccacactcgccgatctaccactactattatggtatggacgtctggggccaagggaccacggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9502 JY8QFUQ01AN4CJ productive Homsap IGHV3-7*01 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAREQSSRGYPLDYW in-frame + tctggattcacctttagtactttttggttgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatatccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9503 JY8QFUQ01ATP88 productive (see comment) Homsap IGHV4-34*10 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaAagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9504 JY8QFUQ01BCHZM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9505 JY8QFUQ01CF35R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 176 58.82 80/136 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9506 JY8QFUQ01BTR4I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9507 JY8QFUQ01DCF12 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 697 80.56 174/216 nt 80.09 173/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); atctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattgatttatcccggcgggagcacattccacgcagactccgtgaCgggggcgcctcatcatctccagagacgagtccaagggtgaggtgtatcttcggatgacgagggtgaaaaccgaagacgcggccgtgtattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtctctgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9508 JY8QFUQ01C2LWF productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9509 JY8QFUQ01CFTTB productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ6*02 F 175 75.81 47/62 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [1.16.38.11] CARAVGQRGYDGTDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcatgttcagcagttattggatgagctgggtccgccaggatccagggaagggctggagtgggtggccaatataaacgaagaaggaagtgagaaatattatgtggactctgggaagggccgattcaggatctccagagacaacgccaagaattccgtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagcagtggggcagcgaggctacgacggtacagacctctggggccaagggaccacggtcatcgtctccacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9510 JY8QFUQ01A948I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacacagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9511 JY8QFUQ01CDG9O productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 822 85.65 191/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - gtcctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9512 JY8QFUQ01BPT8C productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 951 92.73 204/220 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9513 JY8QFUQ01B61T7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9514 JY8QFUQ01B3R8A productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9515 JY8QFUQ01BV9PI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9516 JY8QFUQ01AQWBS productive (see comment) Homsap IGHV4-39*02 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.16.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactggggctgggtccgccagccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaatcctggtcaccgtctcctcacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9517 JY8QFUQ01BJC1Y productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcctcccgctgagcctccgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9518 JY8QFUQ01A2S2M productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaAaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9519 JY8QFUQ01C2LKX productive Homsap IGHV3-9*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CVKDIHGKYSYLMDVW in-frame + cctctggaatcaatcttgatgattatggcctgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaaaaggggtagtgtagcctatgcggactctgtgaagggccgattcaccatctccagagactacgccaagaactccctgtatctgcaaatgaatagtctgagagtagaggacacggccttgtattactgtgtgaaagacatccatggcaaatactcctaccttatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9520 JY8QFUQ01B4X7N productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9521 JY8QFUQ01AY9SW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9522 JY8QFUQ01A8MAI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 924 91.36 201/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + ctctggtggctccatgagcagtggtaattactgctggggctggggccgccagcccccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 9523 JY8QFUQ01B4P9J productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 75 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccGgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9524 JY8QFUQ01CXODK No results 9525 JY8QFUQ01CE0PZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9526 JY8QFUQ01CL1NE productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 798 85.0 187/220 nt 84.09 185/220 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] CTRQGPYLYGFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); ctctggtgtttccgtcagtaacactGattttctattggggTctgggtccgccagtccccagggaagggactggagtggattggcagtgtagattatagtgggagcgcttcctacagccctgccctcaagagtcgagtcatcatatccatagacacgtccaagaaccagttctccatagctctgagttctgtgaccgccgcagacacggctgtctattattgtacgagacagggaccctacctctacggtttcgacgtctggggccaagggaccacggtcaccgcctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9527 JY8QFUQ01CG0FA productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARSRTFYGSANYW in-frame - ctgtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9528 JY8QFUQ01C1PJV productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 591 95.38 124/130 nt 94.62 123/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 X 11 8.X.11 [1.3.31.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9529 JY8QFUQ01CY6CU unproductive (see comment) Homsap IGHV3-7*01 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - stop codons ctctagatcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9530 JY8QFUQ01BW93K No results 9531 JY8QFUQ01C3NBA No results 9532 JY8QFUQ01AGDKF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARRTITAAGRGDDYR in-frame - ctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactaccggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9533 JY8QFUQ01CYRUR productive (see comment) Homsap IGHV1-2*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); ctggatatactttcaccgaccattatgtttactggatgcgacaggGcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9534 JY8QFUQ01A7AMF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 9535 JY8QFUQ01BOTHE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 805 86.11 186/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.37.11] CVKDYGNCGGGRCYSIPLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) ctctggatttacctttagccgctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcattattgatgttaattctttcacatactacgcagactctgttcgggccggttcaccgtgtccagagacgattccaagaacacggtatatctgcaaatgaacagtttgagacccgacgacacggccgtttattattgtgtgaaagattacggtaactgtggtggtggtcgctgctattcgattccccttgactactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9536 JY8QFUQ01BZ7N9 No results 9537 JY8QFUQ01A79PR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9538 JY8QFUQ01BLAI9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 979 95.77 204/213 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [X.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - ggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 9539 JY8QFUQ01BAKGF productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 848 87.33 193/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARGGGWTPYFDSW in-frame - tctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattactgtgcgaggggcggtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9540 JY8QFUQ01DGZ1Q No results 9541 JY8QFUQ01CAE9T unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9542 JY8QFUQ01CYLVO productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - ctggtgggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9543 JY8QFUQ01AWS2C No results 9544 JY8QFUQ01AIFBN No results 9545 JY8QFUQ01B4AHX productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 9546 JY8QFUQ01DVOVU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9547 JY8QFUQ01DG2HL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttccttcccccagg 9548 JY8QFUQ01C8AA1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 934 93.43 199/213 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [X.17.38.11] CARRPAAGSHFALDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ggatacaactttgacaccgattggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgctgactctgataccagatacagtccgtccttccaaggccaagtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcggcctgaaggcctcggacaccgccatctattattgtgcgaggcgtccagcagctggtagccacttcgctttggacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9549 JY8QFUQ01C9MY3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.16.38.11] CAKEGTIVGAAGFGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcgactatggcatgacctgggtccgccaggctccagggagggggttggagtggtcgcatctattaatgccggtggtagtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgggcagcctgggagccgaagacacggccgtatattactgtgcgaaagaaggcaccattgtgggagctgccggatttggctactggggccagggaaccctggtcaccgtctcctcaccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9550 JY8QFUQ01A0LZ5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaagggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 9551 JY8QFUQ01DCRJC unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [4.17.38.11] CARGAPFS**# out-of-frame + stop codons ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9552 JY8QFUQ01CQCZQ No results 9553 JY8QFUQ01C6WRE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 802 85.39 187/219 nt 84.02 184/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [2.17.38.11] CAKVWIELWSAGDHFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctctggattcGatatttactagatatgccatgacctgggtccgccaggctccAagggaagggtctggagtgggtcgcttctatcagtggtagtgggattagTgaaaaagtacgcagacggcgtggagggccgattcaccatctccagagacagttccgagagaacactgtatctacaaatgaacagcctgagagtcgaggacacggccacatattattgtgcgaaagtatggatagagttatggtcggctggggaccactttgacaactggggccagggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9554 JY8QFUQ01A16XV productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9555 JY8QFUQ01CWG23 No results 9556 JY8QFUQ01CXUBO No results 9557 JY8QFUQ01CEYB6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9558 JY8QFUQ01CDH2X unproductive (see comment) Homsap IGHV3-9*01 F (see comment) 892 89.5 196/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] *KDRGSSSKYYFDYW in-frame - stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtatttgtaaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9559 JY8QFUQ01BRBV4 unproductive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY## out-of-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 9560 JY8QFUQ01AOOQB productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9561 JY8QFUQ01C5IDJ No results 9562 JY8QFUQ01COOBL No results 9563 JY8QFUQ01BIXBK No results 9564 JY8QFUQ01CFGTC No results 9565 JY8QFUQ01BJLD5 productive (see comment) Homsap IGHV4-61*02 F (see comment) 632 76.47 169/221 nt 76.02 168/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 2 10 7 16 10.7.16 [1.17.38.11] CARERDKSGGGAHDFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); tctccggtgggcccatcatcactggttactcctcttggacatggatccggcagtccgccggtaagggactggagtggatcggacatatttaccaaggtgggatcaccaattacagtccctccttcaggGggccgagtgaatatgtcggtggactcgtccagggggcagttttccctcagtctgcggtctgtgaccgtcgcagacacggccatctattactgtgcgagagaacgtgataagtcgggcggcggagcgcacgactttgattcctggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9566 JY8QFUQ01ARW22 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9567 JY8QFUQ01BA02U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttaCctggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9568 JY8QFUQ01BFJ67 productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 845 88.37 190/215 nt 86.98 187/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARADYYDTSAYYLDAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 60 of V-REGION: 9 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) cctctgggtacagcttcggaggctctgtTtttgcactgggtccgccaggcttccgggaAaaggactggagtgggttggccgtgtcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggcttatctggaaatgaacagcctgaaaaccgaggacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctggggccaggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9569 JY8QFUQ01AUXOH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcacctttagcatctattccatgagctgggcccgccaggctccagggaaggggctggagtgggtctcatctattaatgataatggtgatagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9570 JY8QFUQ01BGU0C productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 850 88.43 191/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [2.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcgggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9571 JY8QFUQ01BQ3Q6 No results 9572 JY8QFUQ01BQTHQ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9573 JY8QFUQ01AYDQU No results 9574 JY8QFUQ01BXFKE No results 9575 JY8QFUQ01A063J unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 915 90.91 200/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 3 10 7 X 10.7.X [1.17.38.11] CARLTDWWGV#FDHW out-of-frame + ctctggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtggggggtcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 9576 JY8QFUQ01BEN7B unknown (see comment) Homsap IGHV1-3*01 F (see comment) 736 83.1 177/213 nt 82.63 176/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacagcttcactaatcacattatccattgggtgcgccaggccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9577 JY8QFUQ01DFFFS productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 9578 JY8QFUQ01AXPMT No results 9579 JY8QFUQ01CPY5S productive (see comment) Homsap IGHV3-21*04 F (see comment) 741 83.18 178/214 nt 82.71 177/214 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 1 8 7 15 8.7.15 [1.17.38.11] CAKRLTVSSKFAAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) caccggattcactttcagtagttttggcatggcctgggtccgccaggctccagggaagggactggagtgggtcgcagacgttgttagtcctcgcagtatatattatgcagactccgtgaagggccgattcatcatctccagagacaacaacaataacaccgtgtacctgcaaatgaacagcctgaggggcgacgacacggccacatattactgtgcgaaacgtctgacggtgtcttcgaaattcgctgcttttgatgtttggggccatgggacagtggtgaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtcccaggggcttcttcccccag 9580 JY8QFUQ01CHDGD productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9581 JY8QFUQ01CL5FZ unproductive Homsap IGHV3-43*01 F 949 93.52 202/216 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGSYGSYGSDAFDF# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcatatttgaagactataccatgcactgggtccgtcaagctccggggaagggtctggagtgggtctctcttattaattgggatggtggtaacacatactatgcagactctgtgaagggccgattcaccatctccagagacaacaacaagaactccctgcaaatgcaaatgaacagtctgagaactgacgacaccgccttgtatttttgtgcaaagggctcctacgggagttatgggtccgatgcctttgatttttggggccaaggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9582 JY8QFUQ01BI9VQ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtgaccatggcatgcactGgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9583 JY8QFUQ01B4U8S No results 9584 JY8QFUQ01AYY7V productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + cctctggactcagtttcactaacgcctggatgagctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 9585 JY8QFUQ01CAC4E unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1093 98.67 222/225 nt Homsap IGHJ1*01 F 260 100.0 52/52 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CARDRG*WELRAFDPRDET#AEYFQHW out-of-frame + stop codons tccggggacagtgtctctaggaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaagtcgaataaccatcaacccggacacatccaagaaccagttctccctgcagctgaagtctgtgactcccgaggacacggctgtgtattactgtgcaagagatcggggatagtgggagctacgtgccttcgatccccgcgacgaaaccccgctgaatacttccagcactggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9586 JY8QFUQ01CG01D unproductive (see comment) Homsap IGHV1-2*02 F 902 91.98 195/212 nt 91.51 194/212 nt Homsap IGHJ2*01 F 211 88.68 47/53 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [0.17.38.11] CARAPVGWYFDLW in-frame + stop codons in CDR2-IMGT, from codon 58 of V-REGION: 2 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) tggatacaccttcaccggctactatatgtactgggtgcgacaggcccctggacaagggcttgagtggatggcaaagatcaacctaaagtggtgccacagactatgcacagagttttcagggcagggtcaccttgaccagggacatgtccatcaccacagccaccatggagctgagcagtctgagatctgacgacacggccgtgtattattgtgcgagagcccccgtggggtggtacttcgatctctggggccgtggcaccctggtcactgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9587 JY8QFUQ01BP1UC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9588 JY8QFUQ01AVNRN unproductive Homsap IGHV3-48*04 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSDFLLDG#YW out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttacagttTtcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcagactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgattttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9589 JY8QFUQ01AZNRP productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 21 8.8.21 [0.17.38.11] CAGDRGPVFRVVHIGQIYGLDVW in-frame + tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcggggtccggtttttagggtggttcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcacctgcctggtcagggcttcttccc 9590 JY8QFUQ01C9RTB productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + tctctggtgactccatcagcagtaatagtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9591 JY8QFUQ01A8HEJ unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CARLTTAVGGWS#FDIW out-of-frame - stop codons tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtctttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 9592 JY8QFUQ01B9CL3 No results 9593 JY8QFUQ01BLCOT productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1024 98.12 209/213 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + tctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctagtccagggcttcttccccca 9594 JY8QFUQ01BEW1W No results 9595 JY8QFUQ01CVNA8 productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9596 JY8QFUQ01DKFMG unproductive (see comment) Homsap IGHV3-48*01 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcttcagtttgagtacttataccatgGaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9597 JY8QFUQ01CP1NK No results 9598 JY8QFUQ01C8ZP6 unknown (see comment) Homsap IGHV3-21*04 F (see comment) 667 78.54 172/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (78,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactgggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9599 JY8QFUQ01ALJNM productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 668 79.72 169/212 nt 78.77 167/212 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [0.17.38.11] CVRDAETTVSGVAGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaAGggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9600 JY8QFUQ01BXEXG productive (see comment) Homsap IGHV4-39*02 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 18 10.7.18 [1.17.38.11] CARLLRVYDWYSQRGYFDTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccgatggctccatcagcactagtaattactactggggctgggtccgccagcCccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaaggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9601 JY8QFUQ01CWWDM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9602 JY8QFUQ01C7R6J No results 9603 JY8QFUQ01B9XZC No results 9604 JY8QFUQ01AOTW1 unproductive Homsap IGHV3-74*03 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [1.16.38.11] CVREKVVIGT#WFDTW out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagccactggatgcactgggtccgccaaggtatagggaggggctggtgtggcttgcacgcattaacagtgatggcagtagtacagcttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaagacgctttatctgcaaatgaacagtctgagagtcgaggacacggctgtctattactgtgtaagagagaaagtagtaattggaaccgctggttcgacacctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9605 JY8QFUQ01CMQSO productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9606 JY8QFUQ01A84F3 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1015 97.65 208/213 nt 96.24 205/213 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CARLGSGG*SWL#YADYW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'CG' (2 nucleotides at position 127 to 128 in the user submitted sequence), (cause frameshift); tctggtggctccatcagtagttactactggagctggatccggcagGcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacAaacccctccctcaagagtcCGgggtcaccatgtcagtggacacgtccaagaaccagttctccctgaagctgagctctctaaccgctgcggacacggccgtgtattactgtgcgagactagggtccggggggtagtcgtggttattacgctgactactggggccagggaacccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 9607 JY8QFUQ01ARFI3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKKHYNSGTYLYNFDY## out-of-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaagcattataattcggggacttatttatacaactttgactactggggccgggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 9608 JY8QFUQ01CLVA4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 335 88.37 76/86 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame + tcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9609 JY8QFUQ01AYITE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca 9610 JY8QFUQ01C60RS unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - stop codons cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtaggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccaattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9611 JY8QFUQ01B9S8O productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9612 JY8QFUQ01ARMUC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9613 JY8QFUQ01BDPSL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'AT' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccggttATggccatgacttgggtGccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9614 JY8QFUQ01CAQ7C productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9615 JY8QFUQ01CF1GZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggatttaccttcagtagctactggatgcactgggtccgccaagctccggGggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9616 JY8QFUQ01AY45M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9617 JY8QFUQ01C0LUF productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 840 88.32 189/214 nt 87.38 187/214 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD1-1*01 F 3 8 7 16 8.7.16 [1.17.38.11] CARDSHKSTDGDLYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'CAGT' (4 nucleotides at position 82 to 85 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggccccagggaaggggccggagtgggtctcagttatCAGTggttgggggtaatactatatattatgcagactccgtgagaggccggttcaccatctccagagacaactccaagaacatgctgtatctgcaaatTgaatagcctgagagccgaggacacggccgtttattactgtgcgagagactcccacaaatccaccgacggtgacttgtactttgactactggggcccagggaacccgggctcaccgtctcctcagcatccccggaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaatg 9618 JY8QFUQ01BVVXG No results 9619 JY8QFUQ01DF7O5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9620 JY8QFUQ01ATAZY No results 9621 JY8QFUQ01BVA4N productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARKRVPGGTFYGDYW in-frame - agcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9622 JY8QFUQ01BGC57 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + tctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggct 9623 JY8QFUQ01AXX7W unproductive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQW# out-of-frame + stop codons in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtgggggcccagggaaccctagtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccctgacgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9624 JY8QFUQ01AO52M productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tttcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactc 9625 JY8QFUQ01CZ7K3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9626 JY8QFUQ01CFCPT No results 9627 JY8QFUQ01ARJZT unproductive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattagatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 9628 JY8QFUQ01C73AJ No results 9629 JY8QFUQ01CNEC8 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagccCcccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9630 JY8QFUQ01CM68E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9631 JY8QFUQ01AKSQR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggagaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacacgcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 9632 JY8QFUQ01C4C8I No results 9633 JY8QFUQ01B439T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9634 JY8QFUQ01A2EVT unproductive Homsap IGHV3-48*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.16.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccaggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcactggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9635 JY8QFUQ01B3Y5F No results 9636 JY8QFUQ01A9HIP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 829 86.76 190/219 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ggctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9637 JY8QFUQ01DS8Q6 unknown (see comment) Homsap IGHV1-58*01 F, or Homsap IGHV1-58*02 F or Homsap IGHV3-11*01 F or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF 65 100.0 13/13 nt 3 X X 3.X.X [1.X.X.X] null - No rearrangement found tctggattcacct 9638 JY8QFUQ01C5NQN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.16.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcacctttaccaactacgccatgagctggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9639 JY8QFUQ01AS3G0 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 620 76.28 164/215 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found Low V-REGION identity (76,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9640 JY8QFUQ01A6LJQ productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9641 JY8QFUQ01B9J90 unproductive (see comment) Homsap IGHV3-11*01 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDSSTTVTKDYW in-frame + stop codons ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggtagtggtaataccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagattcctcgactacggtgactaaagactactggggctagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9642 JY8QFUQ01BBKH9 productive Homsap IGHV3-11*01 F 1012 96.76 209/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARDMYSSSALFPW in-frame + tctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtagtggtagtatcataaactatgcggactctgtgaagggccgattcaccatctccagggacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatatgtatagcagctcggcccttttcccttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9643 JY8QFUQ01DWIV2 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9644 JY8QFUQ01AHS4R No results 9645 JY8QFUQ01DCY6I productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 997 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggnggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtctttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 9646 JY8QFUQ01C6EVL unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F (see comment) 307 75.45 83/110 nt 8 10 X 8.10.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (75,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggtcgtcgcatgcctggtccagggcttcttccccca 9647 JY8QFUQ01CWX3I unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9648 JY8QFUQ01CZAMZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9649 JY8QFUQ01BHJ6Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9650 JY8QFUQ01ADX32 No results 9651 JY8QFUQ01A19MC No results 9652 JY8QFUQ01AX2V4 No results 9653 JY8QFUQ01AFFCS productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcagg 9654 JY8QFUQ01A9PP5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame + cgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9655 JY8QFUQ01C5X96 productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9656 JY8QFUQ01CQFWM productive (see comment) Homsap IGHV3-48*01 F 1070 100.0 215/215 nt 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.37.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 174 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9657 JY8QFUQ01AJF1Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9658 JY8QFUQ01AYOSL productive (see comment) Homsap IGHV3-9*01 F (see comment) 793 84.93 186/219 nt 84.02 184/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'TTTT' (4 nucleotides at position 61 to 64 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 114 in the user submitted sequence), (cause frameshift) agcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaaTTTTgggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9659 JY8QFUQ01B4V0R No results 9660 JY8QFUQ01BB08I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9661 JY8QFUQ01ANU4J productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9662 JY8QFUQ01C9RK7 No results 9663 JY8QFUQ01DOBUG unproductive (see comment) Homsap IGHV3-48*03 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 9664 JY8QFUQ01AUIPM No results 9665 JY8QFUQ01C5770 No results 9666 JY8QFUQ01ACMHQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 908 91.63 197/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [0.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame + ctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgacgcctctgcagcaccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 9667 JY8QFUQ01DCLEC unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 149 52.07 113/217 nt 8 8 X 8.8.X [1.17.37.X] null - No rearrangement found cctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgaagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 9668 JY8QFUQ01AN7RR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 781 83.78 186/222 nt 82.88 184/222 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); caatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9669 JY8QFUQ01B7CZQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'T' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); gtctcggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaTgggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9670 JY8QFUQ01B2FO6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 831 87.85 188/214 nt 86.92 186/214 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 7 8 17 7.8.17 [1.16.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) tctggattcagcttaagttctatggcatgaactggtccgccagcgtccatggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9671 JY8QFUQ01AHY6R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 9672 JY8QFUQ01CW8LP productive (see comment) Homsap IGHV3-15*04 F 1006 95.05 211/222 nt 93.24 207/222 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.16.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 200 to 200 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtggttggccgtattgCcaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaacCcgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9673 JY8QFUQ01A8CRV productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9674 JY8QFUQ01A67RJ unknown (see comment) Homsap IGHV1-2*02 F (see comment) 462 68.22 146/214 nt 67.76 145/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (68,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9675 JY8QFUQ01CRXKV productive Homsap IGHV4-61*02 F 798 85.0 187/220 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSSSIGGERELDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggtggccccatcagcagtagtggcttcgcctggacctggatccggcagaccgccgggaagggactggagtggatcggacgtgtttatggtagtgggaataccaattacagtccttccctccagagtcgagtcaccatatcagtagagacgtccaagaatcagttctccctgaggttgacttctgtgaccgccgcagacacgggcctatattactgtgcgagagaacatagtagttcgattggcggagagagagaacttgactcctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9676 JY8QFUQ01B0BI5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9677 JY8QFUQ01AGMY9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1016 96.76 209/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.16.38.11] CAKDRITIFSYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtcgccaggntccagggaaggggctggatgggtctgcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9678 JY8QFUQ01CUV36 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame - Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9679 JY8QFUQ01DE83A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9680 JY8QFUQ01AZBQJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1041 96.83 214/221 nt 95.93 212/221 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKDRITIFSYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); cagcctctggattcacctttagcagctatgccatgagctgggtccgGccaggntccagggaaggggctggatgggtctgcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9681 JY8QFUQ01CCVXJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9682 JY8QFUQ01C6ZDR productive Homsap IGHV4-61*02 F 879 89.09 196/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9683 JY8QFUQ01BK9PA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDYGNCAGGRCYSIPLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'TTT' (3 nucleotides at position 98 to 100 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtggtgggTTTttgacatactacgcagacgccgtgcagggccggtttattatttccagagacgattcccagaacacgatagatctgcaaatgaacaatttgagagccgacgacacggccatctattactgtgtgaaagattacggcaattgtgctggtggtcgctgctactcgattccccttgactattggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacaaccacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 9684 JY8QFUQ01B6DWD productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccGggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9685 JY8QFUQ01DCOUL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggattcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9686 JY8QFUQ01DM3S0 No results 9687 JY8QFUQ01A5K3B productive (see comment) Homsap IGHV1-3*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGRYDISGRGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tggatacaccttcactagttTttagtatacattgggtgcgccaggcccccggacagaggcttgagtggatgggatggatcaacgcaggcaacggtcacacaaaatattcacagaagttccaggacagagtcaccattataagggacacatccgcgagcacagcctacatggacctgagcaccctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatattagtggtcgtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 9688 JY8QFUQ01B8WRM productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.16.38.11] CARGDGYNFGGLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) tctggattcaacttcataggttatggcatgcactgggtccgcaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9689 JY8QFUQ01BZD8Y productive Homsap IGHV3-48*01 F 815 86.24 188/218 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame - cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9690 JY8QFUQ01DNUOM productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggCaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9691 JY8QFUQ01CSQCS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 473 68.35 149/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9692 JY8QFUQ01CKPM2 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactCccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9693 JY8QFUQ01BP3KJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9694 JY8QFUQ01A5H4Z unproductive Homsap IGHV3-66*02 F 893 91.51 194/212 nt 90.57 192/212 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.16.38.11] CAKLADTGEWSNRIFI#W out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9695 JY8QFUQ01CWE2H No results 9696 JY8QFUQ01BNPBU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9697 JY8QFUQ01CX7MG No results 9698 JY8QFUQ01CKBGY productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcatctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9699 JY8QFUQ01BID64 No results 9700 JY8QFUQ01C0N7I productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9701 JY8QFUQ01A0N2E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARVRGGLSSGWYESLDYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagttcgaggaggtcttagcagtggctggtacgagtctcttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc 9702 JY8QFUQ01DIJMJ unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9703 JY8QFUQ01BLIOS No results 9704 JY8QFUQ01AL0GQ unproductive (see comment) Homsap IGHV3-11*01 F 902 91.98 195/212 nt 91.04 193/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [0.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - stop codons in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) tctgattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggAtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagaactacttccccgaaccggtgacggtgtcgtggaactcag 9705 JY8QFUQ01B5NOR productive (see comment) Homsap IGHV1-18*01 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARGDIMYYYNSGPFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggttacGagtttttccagttatggtatcaattgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcagcggttacaatggtaacacaaattttgcacagaagttccagcatagagtcaccctgactacggacacatcaacgaggacagcctacatggagctgaggagcctgacatttgacgacacggccgtatattactgtgcgagaggggacattatgtattactataattcgggcccctttgagtactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9706 JY8QFUQ01BL2RY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + tccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 9707 JY8QFUQ01CXL6W No results 9708 JY8QFUQ01CGJGT No results 9709 JY8QFUQ01DNT9I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9710 JY8QFUQ01B4F4X productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagaatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9711 JY8QFUQ01CGDXY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9712 JY8QFUQ01CGK5B productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9713 JY8QFUQ01C01VG productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9714 JY8QFUQ01AMPM6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9715 JY8QFUQ01DJ5FE unproductive Homsap IGHV4-39*02 F 943 91.89 204/222 nt 90.99 202/222 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD4-17*01 F 1 10 7 X 10.7.X [2.17.38.11] CASVTTVSMRMKY## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 70 to 71 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggGCtgggagtggaTttgggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaacccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgccgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9716 JY8QFUQ01C49VP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDIW in-frame - cctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacatctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9717 JY8QFUQ01CKUWN unproductive Homsap IGHV3-13*01 F 876 90.19 193/214 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9718 JY8QFUQ01AYHQY productive (see comment) Homsap IGHV3-7*01 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ggctctggattcagcttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9719 JY8QFUQ01C3HDP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9720 JY8QFUQ01AIKH9 No results 9721 JY8QFUQ01CCJXU productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 853 89.2 190/213 nt 88.73 189/213 nt Homsap IGHJ6*02 F (see comment) 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 8 8 18 8.8.18 [0.16.38.11] CARSDFGAYPTYYYYFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) tggaggcaccttcagtagttacgcaatcagctgggtgcgacaggcccctgggcaagggcttgagtggatggggggatcatccctaagtttggaagaacaaactacgcacagagtttccagggcagagtcacgattaccgcggacaaatctacgaggacagtctacttggagttgagtagcctgcgatctgaagactcgggcgtgtatttctgtgcgaggagtgacttcggggcctaccctacatactactactactttatggacgtctggggccgtgggaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttccccca 9722 JY8QFUQ01A2UAC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9723 JY8QFUQ01BQ8M2 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9724 JY8QFUQ01AY8UC productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9725 JY8QFUQ01BYN0U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [0.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 9726 JY8QFUQ01CM8A1 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagtacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9727 JY8QFUQ01BBSMN productive Homsap IGHV4-4*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARTGYTLAVGVREFDSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01BBSMN ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggcggccccgtcaccaataatgattactactggagttggatccgacagcccgccgggaagaaactggagtggctcgggcgtatttttggaagtgggaccaccaattccaatccctccctcaggggtcggctcaccatgtcactagatccgtctaagaatcagttcaccctgaggttgacctctgtgaccgccgcggacacggccgtgtattattgtgcgagaactggttatactctcgctgttggagtgcgagagtttgactcctggggccagggaaccttggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9728 JY8QFUQ01DEYU2 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9729 JY8QFUQ01AXOBA productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9730 JY8QFUQ01BB67V productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 832 87.5 189/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [2.17.38.11] CARAPGWMNPFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'T' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); gtctccggtggctccatcaccacttactacatcagctggctccggcaGgcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaacTccctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9731 JY8QFUQ01CU4ET unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9732 JY8QFUQ01C6PDY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9733 JY8QFUQ01DNE8U productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatcccgaccagccccaaggtcttcccgctgagcctctgnagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9734 JY8QFUQ01CLJ2C productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9735 JY8QFUQ01CTQJD unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 772 84.98 181/213 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARERGSGPPHRHGRL# out-of-frame - Low V-REGION identity (84,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccatctactactgtgcgagagaaagaggttcggggcccccccacaggcatggacgtctgggggcccagggaccatggtcaccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9736 JY8QFUQ01C9T1K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-6*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAKVDSSSAWDYW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaagtttcatgaatatgccatgatctgggtccgccaggctccaggcaagggtccggaatgggtctcgtctattagtagtactagtaaatacatctattatgcacagtcagtggagggccgattcaccatctccagagacgacgccgagaacgcactgttcctccagatgagcagcctgagtgtcgacgacacggctatctattactgcgcgaaagtcgatagcagttcggcctgggactattggggcccgggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9737 JY8QFUQ01B8VUB unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 9738 JY8QFUQ01BNIXY unproductive (see comment) Homsap IGHV1-8*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [0.17.38.11] CARGPCQWL#YTDYW out-of-frame + stop codons tggatacaccttcaccagttatgatatcaactgggtgcgacaggccgctggacaagggcttgagtggatgggatgggtgaaccctaatagtggtgccacaggctatgcacagaagttccagggcagagtcaccatgagcagggacacctccgaaagtacagcctacgtggagctgagcagcctgggatctgaggacacggccgtgtattactgtgcgagaggcccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9739 JY8QFUQ01CUQ6W No results 9740 JY8QFUQ01B8REE unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [0.17.38.11] CVTSGGSGTDLVPP#DDW out-of-frame + tggatacagctttaacaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggactcatctatcctggtgactctgtaaccatgtacagcccgtccttcgaaggccaggtcaccatctcagccgacaaatccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacaccgccacatattactgtgtgacctcggggggttcgggcacagatttggtcccccccggacgactgggcccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9741 JY8QFUQ01C8RD8 No results 9742 JY8QFUQ01AXSGN No results 9743 JY8QFUQ01AR8PF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 3 8 8 19 8.8.19 [1.17.38.11] CARLPFIVVVTGAFLGHFDYW in-frame + ttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcaacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9744 JY8QFUQ01CFYWU unknown (see comment) Homsap IGHV3-7*02 F 118 60.24 50/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9745 JY8QFUQ01AJ19T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9746 JY8QFUQ01BRNZT productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 9747 JY8QFUQ01BE9IC No results 9748 JY8QFUQ01AMMAC productive (see comment) Homsap IGHV1-2*04 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 14 8.8.14 [0.17.38.11] CTRDTSLDNGAALDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgactactatatgcactgggtgcgacaggGccccaggacaagggcttgagtggatgggatggatcaaccctaaaagtggcggcacaaattatgcacggaagtttcagggctgggtcaccatgaccagggacacatccatcaacactgtctacatggagttgagcaggttgaaatctgacgacacggccatttattactgtacgagggatacttctttggacaacggagccgctcttgatatttggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9749 JY8QFUQ01C5B6A productive (see comment) Homsap IGHV3-74*03 F 856 88.13 193/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); gcctctggattcacGtttccacacctcctggatgGcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9750 JY8QFUQ01C945U productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F (see comment) 210 83.61 51/61 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 2 X X 18 X.X.18 [X.X.20.11] CATDLVTSTPGVLDDAYAFW in-frame - Low V-REGION identity (83,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gaacactgtgtatctgcaaatgaacagtctgagagttgacgactcggctctatatcgctgtgcgacagacttggtgacctccacaccgggagtcctcgatgatgcttatgccttttggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9751 JY8QFUQ01BCMCB unproductive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CARAWLDPLL*LL# out-of-frame + stop codons in FR3-IMGT at codon 103 of V-REGION: 'G' (1 nucleotides at position 217 to 217 in the user submitted sequence), (cause frameshift); ctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattaGctgtgcgagggcgtggctggaccccctactttgactcctggggccagggcaaatctggtcaccgtctcctcagcatccccgaccacgccccaaggtccttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 9752 JY8QFUQ01BZ8ZU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggtccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9753 JY8QFUQ01DQY2Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9754 JY8QFUQ01DGCND productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9755 JY8QFUQ01AJ9GQ productive Homsap IGHV4-39*02 F (see comment) 704 80.09 177/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 10 7 15 10.7.15 [1.17.38.11] CAIHNYYGSGRNYFDHW in-frame + Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggagtctccgccatcggcaccagttccttctggggctgggtccgccagcccccagggaaggggctggagtggatcggagctgttcattacagtggaagtatctcttacacgccggccctcaagagtcgactcaccatgtccttagacacgtcaaaaggtcacttgtccctgagactgacctcagtgacctccgcagacacggctatgtactactgtgccatacacaactactatggatcggggagaaactactttgaccactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9756 JY8QFUQ01B6L4V productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSDYTRYDAQDVW in-frame + ctctggattcaccttcagtagttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagccattagcagtattagtcattacatatattacgcggactcactgaggggccgattcaccatctccagagacaacgccaagaacttactgtatttgcaaatgaatagcctgagagccgaagactcggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 9757 JY8QFUQ01DWYGA No results 9758 JY8QFUQ01BESUC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + tctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9759 JY8QFUQ01DECYW No results 9760 JY8QFUQ01A2L8B unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [2.17.38.11] CARPGGIAYCSGGSCYDPW# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaTcctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9761 JY8QFUQ01C9Q2U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 276 90.91 60/66 nt 89.39 59/66 nt 8 X X 8.X.X [1.3.9.X] null + No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 75 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ttctggattcaccttcagtagttatagcatgaactgggactcagtgaagggccgattcaccttggt 9762 JY8QFUQ01DKE6B unproductive Homsap IGHV4-61*02 F (see comment) 974 93.21 206/221 nt 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.38.11] LVREIPLIAIRTSI#DYW out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgGggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattttttggtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9763 JY8QFUQ01BLV8R productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9764 JY8QFUQ01A6VGQ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 9765 JY8QFUQ01CAB6L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9766 JY8QFUQ01A33GI No results 9767 JY8QFUQ01A7BEI No results 9768 JY8QFUQ01ARSQJ No results 9769 JY8QFUQ01CXYJH productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9770 JY8QFUQ01DFNMK No results 9771 JY8QFUQ01A9LCA unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactggatccgccaagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9772 JY8QFUQ01C996D unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 655 90.51 143/158 nt 89.87 142/158 nt 8 8 X 8.8.X [0.17.19.X] null - No rearrangement found in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 75 to 77 in the user submitted sequence), (do not cause frameshift); cgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaac 9773 JY8QFUQ01BMA6K unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYLNL#DYW out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggcCtggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatatttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9774 JY8QFUQ01BZ27M unproductive Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F 1011 97.2 208/214 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CARGVRTVVTALSYGMDV## out-of-frame + tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtggtaacacaggctatgcacagaagttccagggcagagtcatcatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagttctgaggacagggccgtgtattactgtgcgagaggtgtccgaacggtggtgactgctctttcctacggtatggacgtctggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt 9775 JY8QFUQ01C4TA5 unproductive Homsap IGHV3-74*03 F 1026 97.24 211/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CATGPDYAYAM## out-of-frame - ctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9776 JY8QFUQ01DJFIZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKSPDSGYDSNWLDPW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaacttggcgaagttcgccatgagctgggtccgccaggctcctgggaaggggctggagtgggtctcagagatcagtggctccggtagtaaagtcggatatgcggagtccgtgaagggccgattcaccatctccaaagacaattccaagaacacattgtacttgcaaatgaccgacctgagacccggcgacacggccatttattactgtgcgaaaagtcctgatagtggctacgattctaactggctcgacccctggggcctgggaaccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9777 JY8QFUQ01CV97H productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAARIDSGHYWNAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctggatacagatttCaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9778 JY8QFUQ01C4MA5 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.16.38.11] CARQSVPYTEYFNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagagccgaggacacggctgtgtattattgtgcgagacagtctgtaccatataccgaatatttcaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9779 JY8QFUQ01B3MG7 No results 9780 JY8QFUQ01CY8WM productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9781 JY8QFUQ01CFBLX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9782 JY8QFUQ01BSMZD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9783 JY8QFUQ01AWS99 productive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9784 JY8QFUQ01AYWM5 No results 9785 JY8QFUQ01BOY6G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9786 JY8QFUQ01CHNUD productive Homsap IGHV3-66*02 F 840 88.32 189/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-8*01 F 3 8 7 11 8.7.11 [1.17.38.11] CASHLMVYALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtggcaagtacatgagctgggtccgccaggctccagggcagggactggagtgggtctcagttatctatagtactggtagtacatactacgcagattccgtgaaagggcggttcaccatctccagagacagttccaacaacactctatatcttcaaatttacggcctgagagctgacgacacggctacttactactgtgcgagtcacttaatggtgtatgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9787 JY8QFUQ01AL15Q No results 9788 JY8QFUQ01CSGFJ No results 9789 JY8QFUQ01BAJWO productive (see comment) Homsap IGHV3-30*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaaggggActagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcaccctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcc 9790 JY8QFUQ01CZ1NI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARWDTSGWPFLDYW in-frame + ctctggattcacctttaacaattatgccatgacctgggtccgccaggctccagggaaggggctggagtggctctcatatattagtactagtggtggtaatacataccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacttgctgtatctgcaaatgaataggctgagagtcgacgacacggccgtgtatttctgtgcgagatgggatactagtggctggcctttccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9791 JY8QFUQ01A7782 No results 9792 JY8QFUQ01BKODT productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgGactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9793 JY8QFUQ01BUU4Q unknown (see comment) Homsap IGHV3-16*01 ORF 94 53.45 62/116 nt 8 X X 8.X.X [25.5.X.X] null + No rearrangement found ctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9794 JY8QFUQ01ASXS0 No results 9795 JY8QFUQ01AVQBY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9796 JY8QFUQ01CJW5Z No results 9797 JY8QFUQ01B475P productive (see comment) Homsap IGHV1-18*01 F 970 95.31 203/213 nt 94.84 202/213 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 7 8 20 7.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) tggttacatcttcaccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9798 JY8QFUQ01DPLAU productive (see comment) Homsap IGHV4-34*10 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [2.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift); gtgtctggtgagtccttcactaattactactggagctggGatccgccagtcccccaggaaAAgggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9799 JY8QFUQ01BS1DJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARRTITAAGRGDDYW in-frame - ggcctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcgttcttccccca 9800 JY8QFUQ01DHGEG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 394 86.54 90/104 nt 84.62 88/104 nt 8 8 X 8.8.X [1.16.1.X] null + No rearrangement found in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggcgtggAGagtgggtctcagccattagtggcagtggtagtcggacatatt 9801 JY8QFUQ01CJ8EZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - tctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctattcggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9802 JY8QFUQ01AZS42 productive (see comment) Homsap IGHV3-66*02 F 907 92.02 196/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9803 JY8QFUQ01AECOG unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 222 59.39 98/165 nt 7 8 X 7.8.X [X.17.22.X] null - No rearrangement found Low V-REGION identity (59,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9804 JY8QFUQ01CW651 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F (see comment) 617 75.69 165/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9805 JY8QFUQ01CWKRF productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9806 JY8QFUQ01CAVJ6 No results 9807 JY8QFUQ01CGXHA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 406 89.11 90/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca 9808 JY8QFUQ01CX0CA productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaaaaaaaagtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9809 JY8QFUQ01AVQ0D productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.73 207/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaaAgctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9810 JY8QFUQ01DC50K productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKGLYYYDSSGYRVFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcaactTttgccatgagctgggtccgccaggctccagggaagggactggagtgggtctcgactattagtcctagtggtggtaccacatattacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacgctgtatctgcaaatgaacatcctgagagccgaggacacggccacatattactgtgcgaaaggactatattattatgacagtagtggttatcgggtctttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9811 JY8QFUQ01CRPMT productive (see comment) Homsap IGHV3-7*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARATNADVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); cctctggattcacctttaGgggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9812 JY8QFUQ01DDSS5 No results 9813 JY8QFUQ01BOUSY No results 9814 JY8QFUQ01AODPS productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 733 82.41 178/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDWGGSFDRYYFDYW in-frame - Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaagatcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9815 JY8QFUQ01C0UJ2 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CASRLRSSGGY## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9816 JY8QFUQ01CGLOU unproductive Homsap IGHV3-7*01 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [1.16.38.11] CARGSYWHYDTFGDY# out-of-frame - in FR2-IMGT, from codon 44 of V-REGION: 2 nucleotides (from position 44 in the user submitted sequence), (cause frameshift) ctctggatttacttttaacaactattggatgacctgggtccgcagccccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9817 JY8QFUQ01CSNZ1 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARHEG*QPLLLLWLL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggataacagccgttactactactttggctactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9818 JY8QFUQ01CFBQI productive (see comment) Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.16.38.11] CXSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) gcctctggattcaggtttagcatctattggtgagctgggtccgccaggctccagggaaGggggctggagtgggtggGccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtntgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9819 JY8QFUQ01BA3JA unproductive Homsap IGHV3-7*01 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGGNGDLDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 11 to 12 in the user submitted sequence), (cause frameshift); gacctctggaGTtcaacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9820 JY8QFUQ01CGQ0G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9821 JY8QFUQ01CM5G9 unproductive (see comment) Homsap IGHV4-61*01 F 947 92.31 204/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CTRGAVHL*QPV# out-of-frame + stop codons tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacacttatgacagcccgtggggacaggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccca 9822 JY8QFUQ01CZVCH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9823 JY8QFUQ01A5ZUC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + tctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9824 JY8QFUQ01CUETO productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9825 JY8QFUQ01BWRWC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'N' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctggattcagcttcagtacctataacatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatNgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9826 JY8QFUQ01DI5NC No results 9827 JY8QFUQ01C9VWY No results 9828 JY8QFUQ01BPX9U productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 932 92.2 201/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) ggcctctggattcaccCtttggttattatggcatgactggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9829 JY8QFUQ01A3G8O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9830 JY8QFUQ01AH5V2 productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9831 JY8QFUQ01A6EQ2 unproductive Homsap IGHV3-66*02 F 916 92.49 197/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CSTPTYCRGGSCSQ#FDYW out-of-frame + tctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagattttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9832 JY8QFUQ01B4U53 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9833 JY8QFUQ01AXBN3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgagacgn 9834 JY8QFUQ01DJ538 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 330 72.87 94/129 nt 8 8 X 8.8.X [2.17.8.X] null - No rearrangement found Low V-REGION identity (72,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcgtctttaacaactatgccatgggctgggtccgccaggctccagggaaggggttggagtgggtctcatctattagtactagtggtcatcgcctgcctggtccagggcttcttccccca 9835 JY8QFUQ01ADCX5 productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9836 JY8QFUQ01ABSIT unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 X 10.7.X [2.17.38.11] CARRWASNGWSW#YFDYW out-of-frame - in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgagcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9837 JY8QFUQ01CXFX3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CSIRMLGTTGVDY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcacctttagcagctatgccatggactgggtccgccaggctccagggaaggggctggagtgggtctcagatattactggtggtggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggatacggccatatattactgttcaataaggatgctgggaactactggtgtggactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgctgcctggtccagggcttcttccccca 9838 JY8QFUQ01C2FQW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9839 JY8QFUQ01B7VGR productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); tctctggtggccccatcagcagcagcacttactactggacttggatGccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9840 JY8QFUQ01BECVX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9841 JY8QFUQ01CGFEU unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 9842 JY8QFUQ01AO2RA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 598 75.46 163/216 nt 75.0 162/216 nt 8 7 X 8.7.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (75,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9843 JY8QFUQ01CH6NP No results 9844 JY8QFUQ01B3VCX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - cctccgggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9845 JY8QFUQ01C92F8 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtctngcctgcctggtccagggcttcttccccca 9846 JY8QFUQ01BPEL9 productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9847 JY8QFUQ01BEQRC unknown (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 90.13 201/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggtttccCccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggtacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 9848 JY8QFUQ01DQDNF productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaagggggctggagtgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9849 JY8QFUQ01CC0U5 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt 86.88 192/221 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARTYTYRNAFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'CCTG' (4 nucleotides at position 15 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctcgggtgactccCCTGagtgccagtagtagttTtctactggggctgggtccgccagcccccagggaagggactggagtggattgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccagaaccaggtctccctgacgttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9850 JY8QFUQ01AN9JJ No results 9851 JY8QFUQ01CP9PQ No results 9852 JY8QFUQ01A9BQ0 unproductive Homsap IGHV3-7*03 F 932 92.2 201/218 nt 90.83 198/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'TGG' (3 nucleotides at position 65 to 67 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); cctctggatttagctttagaaccttttggatgagctgggtccgccaggctccaggggaggggcgTGGagagtgggtggccaaTcataaagtcagatgGgaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9853 JY8QFUQ01BIQFD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9854 JY8QFUQ01DFYTQ No results 9855 JY8QFUQ01B3OLZ productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9856 JY8QFUQ01CR5OE productive (see comment) Homsap IGHV3-7*01 F (see comment) 687 80.37 172/214 nt 79.44 170/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [0.17.37.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccgAgtggtgggtgccaacatatccccagacggaaatacgaaatatttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9857 JY8QFUQ01DHUBM productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARGTMIPRSFDNW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'TG' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift); gtctttggtgggtccttcagtggttactactggagctggatccgccagtccccagggaaggggctggagtggattTGgggcaaatcaatcatagtggagacaccagctataatccgtccctcaagagtcgagtcaccatttcaatagacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtgtattactgtgcgagaggcacaatgataccgagaagttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9858 JY8QFUQ01CYD71 No results 9859 JY8QFUQ01B9ZFO No results 9860 JY8QFUQ01BD2HK No results 9861 JY8QFUQ01AUBMD productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame + tggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatccgcctgcctggtccagggcttcttccccca 9862 JY8QFUQ01CB55E No results 9863 JY8QFUQ01DWET8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9864 JY8QFUQ01B6JVQ productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9865 JY8QFUQ01C5YIK productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 9866 JY8QFUQ01DVH46 No results 9867 JY8QFUQ01AEOI2 productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9868 JY8QFUQ01AWYUH No results 9869 JY8QFUQ01CXCAE productive Homsap IGHV3-66*02 F 863 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame - cctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9870 JY8QFUQ01CY86E No results 9871 JY8QFUQ01B69EI No results 9872 JY8QFUQ01BM9NP productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 196 to 196 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccTggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9873 JY8QFUQ01AEKQ9 productive Homsap IGHV3-74*03 F 811 87.62 184/210 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 7 8 13 7.8.13 [X.17.38.11] CVRDSDSSASYFAHW in-frame + ttcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 9874 JY8QFUQ01BD2XN No results 9875 JY8QFUQ01CJOO9 unknown (see comment) Homsap IGHV3-16*01 ORF, or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-35*01 ORF or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 139 88.57 31/35 nt 8 X X 8.X.X [1.2.X.X] null - No rearrangement found ctctggattcaccttcagcaaccataacatgaact 9876 JY8QFUQ01CQZGU productive Homsap IGHV1-8*01 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame + tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9877 JY8QFUQ01CLTE0 productive (see comment) Homsap IGHV3-11*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 89 to 97 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9878 JY8QFUQ01BKHHV productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1009 98.1 206/210 nt 97.14 204/210 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 7 8 16 7.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); cacaactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatGggggatcatctatcctggtgactctgataCccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9879 JY8QFUQ01B1F8H No results 9880 JY8QFUQ01AKGC4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9881 JY8QFUQ01AV7KG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.16.38.11] CAKDQSCIVGPC#FDYW out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttGatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9882 JY8QFUQ01C2MXP unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt 8 7 X 8.7.X [4.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 9883 JY8QFUQ01CUDAI unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPHRHGRL# out-of-frame - Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctgggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9884 JY8QFUQ01A9NLW unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ6*02 F (see comment) 94 61.29 38/62 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRPLREFDC## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggtccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctcggtccagggcttc 9885 JY8QFUQ01BJJ76 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - tctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9886 JY8QFUQ01C34Y1 No results 9887 JY8QFUQ01ANHIG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9888 JY8QFUQ01DJ4YH productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 385 89.58 86/96 nt 88.54 85/96 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.32.11] CARSDEEYSYGDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 23 to 27 in the user submitted sequence), (cause frameshift); gcgtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9889 JY8QFUQ01ANG49 productive (see comment) Homsap IGHV3-66*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctCcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9890 JY8QFUQ01B3AFP productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1011 95.07 212/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcacccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctccttcaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9891 JY8QFUQ01BC5ZQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 980 95.35 205/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.16.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctggattcacctacagcagctatgccatgagctggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9892 JY8QFUQ01ALBF8 No results 9893 JY8QFUQ01ANMRQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9894 JY8QFUQ01CQEH2 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccgaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9895 JY8QFUQ01COGUP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9896 JY8QFUQ01A8J17 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1039 98.15 212/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [2.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons tctcctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9897 JY8QFUQ01CRDMB No results 9898 JY8QFUQ01CUFLZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 9899 JY8QFUQ01B8O1A productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9900 JY8QFUQ01C0EU8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9901 JY8QFUQ01AX7BT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + tctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9902 JY8QFUQ01AQBBV unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 115 54.2 71/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons gtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9903 JY8QFUQ01ARPT2 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDF* in-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctccggtggcaccatcaccagttactacgtgagctggctccggcagcCccccagggaagggactggagtggattgggtgtatctcttatagtgggagcactacctacaactcctccctcaagagtcgagtcaccatatcaggagaagggtccacgcgccagttctccctgaggctgagctctgtgaccgttgcggacacggccgtgtattactgtgcgcgagccccaggatggatgaatccctttgacttctagggccagggcactctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9904 JY8QFUQ01AO4GF unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY#W out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagggtcgtattggcattatgataccttcggcgactatttggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 9905 JY8QFUQ01CAFC1 productive Homsap IGHV3-72*01 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9906 JY8QFUQ01CC682 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9907 JY8QFUQ01A7S16 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1009 98.1 206/210 nt 96.67 203/210 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 7 8 16 7.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cacaactttaccggctactggatcggctgggtgcgccagatgcccgggCaaaggcctggagtggatGggggatcatctatcctggtgactctgataCccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9908 JY8QFUQ01BH7IB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDIGGRYSYW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgcaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9909 JY8QFUQ01B2OZJ No results 9910 JY8QFUQ01DDP29 No results 9911 JY8QFUQ01CDP4D productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAREGGRGSSSEDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'TC' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); gcctctggattTCagccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagagggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9912 JY8QFUQ01BMULJ productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9913 JY8QFUQ01BY0XS productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9914 JY8QFUQ01BQXPO productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 403 78.79 104/132 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 6 18 X.6.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Low V-REGION identity (78,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9915 JY8QFUQ01AHRBA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 691 80.75 172/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9916 JY8QFUQ01BF9YK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1002 96.73 207/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARTTSSSGWYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); ctctggaggctccattagtaattactacCtggagttgGgatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaatcagttcttcctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgaggactacttctagtagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9917 JY8QFUQ01C61BA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 998 96.28 207/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctatggtgggtccttcagtggttacacctggaactggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgtccaacaaccagttctccctgaagctgagctctgtgaccgccgcggacacggctgtgtatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccc 9918 JY8QFUQ01BXWLQ productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9919 JY8QFUQ01B1949 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9920 JY8QFUQ01BTDOA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 9921 JY8QFUQ01BP7OM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 8 10 7.8.10 [1.16.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggattcagcttaagttctatggcatgaactgggtccgccaagctccagggaaggggctgtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9922 JY8QFUQ01AH3ST productive (see comment) Homsap IGHV1-18*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-22*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARTPRIVVVPSADYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacatctttagtagttatggtctcaggtgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcagcgtttacagtggtaacgcaaattatgcacagaagttccagggcagagtcaccatgaccacagacagatccacgaccacagcctacatggaactgaggggcctgagatctgacgacacggccgtgtattactgtgcgagaacccctaggatagtagtggtcccctccgcagactacggtatggacgtctggggccaagggaccacggtccgcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcancgcctgcctggtcagggcttcttcccc 9923 JY8QFUQ01CBDCA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctgggttcaAtttttggccactataccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9924 JY8QFUQ01BOI5P No results 9925 JY8QFUQ01C7H6S productive Homsap IGHV4-39*02 F 947 91.86 203/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.17.38.11] CARRYSWNYERFDPW in-frame + tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9926 JY8QFUQ01A14EE productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9927 JY8QFUQ01CJW2Z productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatgGgatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaaGgccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9928 JY8QFUQ01BLRMD productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 330 88.24 75/85 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame + caccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 9929 JY8QFUQ01A7KOE productive (see comment) Homsap IGHV3-48*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRAASGTSFDNW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacctatgccatgaactgggtccgccaggctccagggaaggggctggaatggAttttcatacattagtactagtagtatacccatatactacgcagactctgtgaagggccgattcaccgcctccagagacgatgccaagaactcgctgtatctgcaaatgaacggcctgagagacgaggacacggctatgtattactgtgcgagaggcagagcagcatctggtacttcttttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9930 JY8QFUQ01A5ZSM No results 9931 JY8QFUQ01A52AK unknown (see comment) Homsap IGHV4-61*02 F (see comment) 270 58.06 126/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (58,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9932 JY8QFUQ01AHHQ3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9933 JY8QFUQ01AO4OI No results 9934 JY8QFUQ01CZNG1 unproductive (see comment) Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDSVPRVVRGC#YHFDYW out-of-frame + stop codons ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggtcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 9935 JY8QFUQ01CKI1Y productive Homsap IGHV1-2*02 F 1029 98.13 210/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARAIDFGSGDKRGFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcaccggctactctatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctaacagtggtggcacaaactatgcacagaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggagctgagcaggctgacatctgacgacacggccgtgtattactgtgcgagagccatcgattttgggagtggtgacaaacgggggtttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9936 JY8QFUQ01DJE0A No results 9937 JY8QFUQ01B2LWA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 639 76.96 167/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9938 JY8QFUQ01B1WL0 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + cctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggcaacgtggtcatcgcctgcctggtccagggcttcttccccc 9939 JY8QFUQ01AHCGW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 830 90.15 183/203 nt 89.66 182/203 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 3 5 7 21 5.7.21 [X.17.38.11] CARLTPLTMVPGTHYYYHSMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'CACAACCCCTCCCTCCTG' (18 nucleotides at position 111 to 128 in the user submitted sequence), (do not cause frameshift); ccatgactggttactactggagttggatccggcggcccccaggtaagggactggagtggattggctatatctactacaccgggtacaacaactacaacccctccctcatcCACAACCCCTCCCTCCTGagtcgactcaccatatcagtcgacacgtccaagaaccagttctctctgacgctgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagattgacacccctgactatggttccgggaactcactactattaccacagtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9940 JY8QFUQ01AWZXQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctccggattcaCcctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9941 JY8QFUQ01A6YG1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 645 75.98 174/229 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 8 10 8.8.10 [5.17.38.11] CGTFGGTHFDDW in-frame + Low V-REGION identity (75,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release aaccggaatcagattcggaagcaaattcggcaatgcctgggtcggttgggtgcgccagaagcccgggaaaggcctggagtggatgggaatcattcatccgagtgactctgaggctagatatggtccgtccttcaaaggccaggtcaccttctcggtcgacaagtccaccgatatcgcctacttgaattgggaccgcctggcggcctcggacaccgccacatattattgtggtacctttggtgggacccactttgacgactggggccagggaactgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9942 JY8QFUQ01BSU4G unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*06 F (see comment) 476 68.84 148/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (68,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctatggtgggtccttcagtggttactattggagctggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggaggcaccaactacaacccgtccctcaagagtcacggaagaattgtattactaccagctgctatgagagggatttgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag 9943 JY8QFUQ01DTFU3 productive (see comment) Homsap IGHV3-66*03 F (see comment) 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVKDMQGVGDIAIGFDYW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01DTFU3 ; 7 AA in Homsap_IGHV3-66*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 98 of V-REGION: 'A' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); gcctctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaaggggctggagtgggtctcaggtattagtgctcgtggtagtagtgcgtactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcagatgaacagcctgagacctgaaAgacacggctttgtattactgtgtaaaagatatgcaaggagtcggggacatagcgattggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9944 JY8QFUQ01CSJ9L No results 9945 JY8QFUQ01COQVX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9946 JY8QFUQ01DM14N unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.37.11] CMNEFGYCSGG# out-of-frame - in FR3-IMGT, from codon 89 of V-REGION: 1 nucleotides (from position 171 in the user submitted sequence), (cause frameshift) gctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtattgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9947 JY8QFUQ01B5CJQ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [2.16.38.11] CVVQILGATIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccaggaagggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9948 JY8QFUQ01DQMOY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt 91.67 198/216 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-10*01 F 1 7 8 X 7.8.X [2.16.37.11] CARDMGSGRYFEPYDY# out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagtagtttgccatgacctgggtccgtcaggctccagggaagggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgagggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagatatgggttcgggaagatactttgaaccttatgactactgggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9949 JY8QFUQ01CII48 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 823 87.04 188/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame - tctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctctaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9950 JY8QFUQ01AJ990 No results 9951 JY8QFUQ01C7E6O No results 9952 JY8QFUQ01CL6TY No results 9953 JY8QFUQ01DUSC7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKDWGPNRQMWFGESLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'GCTGTTGCC' (9 nucleotides at position 94 to 102 in the user submitted sequence), (do not cause frameshift); gcctctggattcacgttcagcagctatgccatgacctgggtccgccagactccagggaaggggctggagtgggtctcaactattcatggcggtGCTGTTGCCggtggcaccacagactacgcggtctccgcccagggtcgattcaccatctccagagacaattccaagagcacactgtatttgcaaatgagcgacctgagacccgaggacacggccctctatttctgtgtgaaagactggggccccaatcggcagatgtggttcggggagagtctctggggccagggaactctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9954 JY8QFUQ01CF976 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcacctttagtaactcttggatgagttgggtccgccaggcaccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 9955 JY8QFUQ01ALN7I productive Homsap IGHV4-61*03 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + ccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9956 JY8QFUQ01ALA6P No results 9957 JY8QFUQ01CTAB8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVVQILGATIDYW in-frame + ctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 9958 JY8QFUQ01C52U4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 84.02 184/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9959 JY8QFUQ01C4FA2 No results 9960 JY8QFUQ01CF6ST productive Homsap IGHV3-7*01 F 828 87.1 189/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccgttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9961 JY8QFUQ01AXLC8 No results 9962 JY8QFUQ01BR9Q4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKRWRASNGHFDYW in-frame + ctctggattcacctttagcagcttttccatggggtgggtccgccaggctccagggcggggactggagtgggtctcagccattgacggtcttactggtggtacatattacgcggactccgtgaggggccgattcaccatctccagagacgattccaagaacacactgtatctgcaaatgaatagcctgagagccgaggacacagccatatatcactgtgcgaagcggtggcgtgcttccaatggccactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 9963 JY8QFUQ01AX25U No results 9964 JY8QFUQ01DXDJW productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ6*02 F (see comment) 205 83.05 49/59 nt Homsap IGHD5-24*01 ORF 3 8 8 11 8.8.11 [2.17.38.11] CARPRYGYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); ggggttctggatacgactttaacaactactgGgatcggctGgggtgcgccagatgcccgggaaaggcctggagtggatgggaatcatctttcctggtgactctgatatcagatatagtccgtcgttccaaggccaggtcaccatctcagtcgacaagtccatcggcaccgcctacctgcaatggagcggcctgaaggcctcggacaccgccacttattattgtgcgagacctagatacggatacggcttggacgtctggggccaagggaccacggtcaccgtctcctcagcccccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9965 JY8QFUQ01CIRGT unproductive Homsap IGHV3-11*01 F (see comment) 963 94.01 204/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] YARRRDYGDYGDGFDY## out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactatgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 9966 JY8QFUQ01A1JOY No results 9967 JY8QFUQ01BD8XY productive (see comment) Homsap IGHV3-11*01 F 792 85.25 185/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 7 8 16 7.8.16 [1.17.38.11] CVRDGARRTNQWLAHDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggattcagctttatgccttctatatgggttgggtccgccaggctccaggaaaggggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9968 JY8QFUQ01DFFYM No results 9969 JY8QFUQ01DN8E2 No results 9970 JY8QFUQ01DCNR9 No results 9971 JY8QFUQ01BXLK3 No results 9972 JY8QFUQ01CNJCD productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 9973 JY8QFUQ01DTGIL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.16.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacatactggatgcactgggtccgccaagtccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9974 JY8QFUQ01C68VA unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRGLY*WCMLCRRLL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggtttgtactaatggtgcatgctatgtcgccgacttctggggcccagggaacccaggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9975 JY8QFUQ01BQIY5 No results 9976 JY8QFUQ01AU2EL unknown (see comment) Homsap IGHV3-66*02 F 753 92.53 161/174 nt 8 7 X 8.7.X [4.17.21.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta 9977 JY8QFUQ01C52KT productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9978 JY8QFUQ01BP884 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaaggggaccacggtcaccggtctcctcagcctccacccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9979 JY8QFUQ01CLGUE unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLPFIVVVTGAFLGHFDY## out-of-frame + ttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9980 JY8QFUQ01DOXWU unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 804 86.45 185/214 nt 84.58 181/214 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARRWARQRLVMDYFDYW# out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'ACTATTG' (7 nucleotides at position 31 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'T' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); ctctggtggActccatcagtagtgactcatACTATTGggggctggatccggcaGgcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaacTgggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggggccaggggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9981 JY8QFUQ01CN374 No results 9982 JY8QFUQ01AXNOE productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9983 JY8QFUQ01ASS6V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9984 JY8QFUQ01C3PTZ productive Homsap IGHV4-59*03 F (see comment) 728 82.33 177/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARHEGSYYDTAGYSDAFDIW in-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggcgtctccatcaccgattacttctggagttggatccggcagtccccaggagggcgactggagtggatctcatatatctatcacactgggaccaccaagtccaacccctccctcaagagccgagtcaacatgtcactggacaggtccaagaaccaattttccctgagcttgaagtccgtaaccgcagcggacacggccgtctattactgtgcgagacacgagggaagttactatgatacggctggttattcggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccca 9985 JY8QFUQ01BFXV9 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9986 JY8QFUQ01CHGAZ No results 9987 JY8QFUQ01DD9NX unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 992 96.24 205/213 nt 95.77 204/213 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 73 60.42 29/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [0.17.37.11] CARGTAASRLLXL# out-of-frame - in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 211 in the user submitted sequence), (cause frameshift) tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagntacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattatgtgcgagggggacagcagcttcgagacttttantactggggccaggggaaccctggtcaccgtccccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9988 JY8QFUQ01A6B1B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame - ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9989 JY8QFUQ01BGWR7 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAEKKVRAPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcagagaaaaaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9990 JY8QFUQ01DWB0T productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 9991 JY8QFUQ01AQ0QS unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [2.17.38.11] CAARIDSVITG#AFDIW out-of-frame - ggctctggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtgtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 9992 JY8QFUQ01CI01U unproductive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDY* in-frame + stop codons in FR3-IMGT at codon 74 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtgggctctgtgatggAgccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactgaggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag 9993 JY8QFUQ01C05SU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9994 JY8QFUQ01C0IGV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 9995 JY8QFUQ01BEL27 No results 9996 JY8QFUQ01ASN9O productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcggcagttataggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 9997 JY8QFUQ01APBJY productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 9998 JY8QFUQ01DQFEE productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 9999 JY8QFUQ01C6CH8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.37.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 127 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagatactggGatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaaggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10000 JY8QFUQ01BRFFP productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 885 90.65 194/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [0.17.38.11] CAREQFYYNSGTYHHYHMDVW in-frame - tggagacacattcaccagctatgctatcagctgggtgcgacaggcccctgggacaaggcttcagtggatgggagggatcatccccagatatggtatatcacactacgcacagaagttccagggcagagtcacgattaccgcggacagatccacgagcacagcctacatggagctgaccagcctgacgtctgaggacacggccctgtattactgtgcgagagaacaattttactataatagtgggacttatcaccattaccatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10001 JY8QFUQ01CIJSW productive Homsap IGHV4-61*02 F (see comment) 776 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERGTAVGGARELDSW in-frame + Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtggccccgtcagcagtgatggttactactggacctggatccgccagcccgccgggcagggactggagtgggtcggacgtgtttccagtcgtggggagaccgactacagttcctccctcaagagccgaatcaccatgtcaatagacacgtctaagaaccagttctccctgaggttgaactctgtgaccgccgcagacacggccctatactactgtgcgagagagcgcggtactgcggttggcggagcgagagaacttgactcctggggccagggatcccaggtcaccgtctcgtcagcatcccccgaccagccccaaggtnttccccgtgagctctcgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10002 JY8QFUQ01AEMV4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10003 JY8QFUQ01B82OW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.02 200/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10004 JY8QFUQ01AX7NA No results 10005 JY8QFUQ01BBF1T productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYG in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaGggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactacgggggccagggaaccctggtcaccgtctcctccgcatcccctgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 10006 JY8QFUQ01A55GJ unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 131 52.11 99/190 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10007 JY8QFUQ01BODQ3 unknown (see comment) Homsap IGHV5-51*05 F 149 56.62 77/136 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found gttctgcatatagtttttccagttactggatcgcctgggtgcgccagatgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10008 JY8QFUQ01BU0QK No results 10009 JY8QFUQ01AVC9I No results 10010 JY8QFUQ01CNO7Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10011 JY8QFUQ01CKARQ No results 10012 JY8QFUQ01AF2VS No results 10013 JY8QFUQ01AJ3KH productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggagccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10014 JY8QFUQ01BGWHY No results 10015 JY8QFUQ01DP1AC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 632 76.47 169/221 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-10*01 F 3 10 7 20 10.7.20 [1.17.38.11] CATSTTRVRGAIRNLVTWFDPW in-frame + Low V-REGION identity (76,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgggtgtctccacaaccagtcaatttaacttctgggtctggatccgccagcctccagggaaggcaccggagtggatagccagttcacgttatggagggaagacgttttacaatccgtcgctcgagagtcgggtcaacatgtctctgagcacgtctaagaatcagttttacctgaacctgatgtctgtgaccgccgcagacacggctgtttatttctgtgcgacgagcaccactcgagttcggggagccatcaggaaccttgttacctggttcgacccctggggcccgggaactcgagtgactgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10016 JY8QFUQ01C380Y unproductive (see comment) Homsap IGHV3-9*01 F 445 90.74 98/108 nt 89.81 97/108 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [1.15.11.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10017 JY8QFUQ01DJCM2 No results 10018 JY8QFUQ01AG17U unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10019 JY8QFUQ01CD9A5 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10020 JY8QFUQ01ABZPQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10021 JY8QFUQ01BMW48 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.37.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10022 JY8QFUQ01BT8I3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.37.11] CAKGQFGTVMDY# out-of-frame + in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) tctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggatggggctgcagtgggtcgcaaccattagtggaagtggcgacagaacattctacgcagactccgtgaagggccgcttcatcgtttccagagacaactccaagaacacgctgtatctgcaaattaccagcccgagagccgaggacacggccgtttttattgtgcgaaaggccagtttggtaccgtcatggactattgggccagggaacccaggtcgtcgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10023 JY8QFUQ01C7FQ1 No results 10024 JY8QFUQ01B4PYG unproductive (see comment) Homsap IGHV3-7*01 F 848 87.33 193/221 nt 85.52 189/221 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [2.17.38.11] CARGDEFLEW*T#FDPW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'CT' (2 nucleotides at position 39 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 62 to 64 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); cctctggagttcagtcttaatgaacctactggatgaacCTggggtccgccaggctccagggGAAaaggggctggagtgggtAggccaatatGaaaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagaggcgacgaatttttggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10025 JY8QFUQ01BIC4N unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10026 JY8QFUQ01AFZBJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 7 8 12 7.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'A' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctggattccagttagcaactatGgccatgagctgggtccgtcaggctcctgggaaggggctggagtAgggtctcaactattagtaaagacggtgtttacacctactAaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10027 JY8QFUQ01AX71G unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSVPRASEAAYHFDY## out-of-frame + cctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattgggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10028 JY8QFUQ01B8ZVD productive (see comment) Homsap IGHV3-7*03 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctccggattcaAtttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10029 JY8QFUQ01BQGL9 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10030 JY8QFUQ01DWCPJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKIDSRNYDFLEWLLC##W out-of-frame - ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgactttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10031 JY8QFUQ01A4UD9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame - cctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10032 JY8QFUQ01DBWXT unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt 90.58 202/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD5-18*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTAPSETYATEYFAMDV# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgccCcccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctgggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10033 JY8QFUQ01B3EO7 No results 10034 JY8QFUQ01AV4S5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 620 93.01 133/143 nt 92.31 132/143 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 10 7.1.10 [1.X.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01AV4S5 ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) cctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10035 JY8QFUQ01CDEOP productive Homsap IGHV4-39*02 F (see comment) 762 83.18 183/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10036 JY8QFUQ01BJH05 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10037 JY8QFUQ01A7U9L unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 10038 JY8QFUQ01C534S No results 10039 JY8QFUQ01ARTV6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10040 JY8QFUQ01BP904 productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10041 JY8QFUQ01B376D unproductive (see comment) Homsap IGHV3-7*01 F 896 90.37 197/218 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVIPGRGNYA#FDVW out-of-frame + stop codons cctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgctttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10042 JY8QFUQ01BUVXP productive Homsap IGHV4-39*02 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame - tctctggtggctccgtcagtaggagtgcctactactggggctggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10043 JY8QFUQ01BD2RN productive Homsap IGHV3-15*07 F 939 91.48 204/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-12*01 F 3 8 10 12 8.10.12 [1.17.38.11] CATGQRGFDAFDLW in-frame + ccctggtctcactttcagtgacgcctggatgaactgggtccgccaggctccagggaaggggctggagtggattggccgtattaagaacaacactgatggtgggacaccatactacgctgcacccgtgaaaggcagattcaccatctcaagagatgactcaaagaagacgatgtatctccaaatgaacaacctgaaaatcgaagacacagccgtgtattattgtgcgacaggacagaggggctttgatgcttttgatctctggggccaagggacactggtcaccgtctctgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10044 JY8QFUQ01CC2G5 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10045 JY8QFUQ01AHRU1 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10046 JY8QFUQ01DACIO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10047 JY8QFUQ01BC5MC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.16 186/221 nt 83.26 184/221 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 10 7 21 10.7.21 [1.17.38.11] CARRLPLGSSAWLETTHDAFDIW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tgtctggtgaatctatcgacagaaatgcttatttttggggctggatccgccagcccccaggggaggggctggagtgggttgggagtacctcttctaatggGgaacaccttctatagtccgtccctcCaaaagtcgagtcaccttgtccgtagacacgtccaggaaccttgtctccctgaacctgaggtctgtgaccgccgcagacacggctgtatattactgcgcgagacgactgcccttagggagcagcgcctggttagagacgacccacgatgcttttgatatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10048 JY8QFUQ01C4CXC No results 10049 JY8QFUQ01BM5IX No results 10050 JY8QFUQ01BHN1C productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.37.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10051 JY8QFUQ01CUU6H productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtgaccatggcatgcactGgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10052 JY8QFUQ01BHVUT No results 10053 JY8QFUQ01AWK5D No results 10054 JY8QFUQ01ANJX1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10055 JY8QFUQ01BTVML productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10056 JY8QFUQ01ASH2F productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10057 JY8QFUQ01CTBUY productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10058 JY8QFUQ01DKRQ7 productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 925 90.99 202/222 nt 89.64 199/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'AG' (2 nucleotides at position 102 to 103 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagtggtcgCttactactggagttgggtccggcaTgcccccagggaagggactggagtggattggtcatttctatcacattAGgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10059 JY8QFUQ01AFKF1 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10060 JY8QFUQ01AMEKO productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 2 9 7 15 9.7.15 [1.17.38.11] CLRCHFGTGYYYYFDYW in-frame - tctggtggctccatcgccagtagtaactggtggagttgggtccgccagtccccagggaaggggctggagtggattggagagatctatcatactgggaccgtcaactacaacccgtccctcatcagtcgagccaccataggagtggacaagtccaagaatgagctctccttgaggctgacctctgtgaccgtcgcggacacggccgtatattattgtttaagatgtcactttgggactggttattattactactttgactactggggccagggattgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10061 JY8QFUQ01BXIOU No results 10062 JY8QFUQ01DU1MH productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1034 98.14 211/215 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10063 JY8QFUQ01AUF6C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10064 JY8QFUQ01DWWER productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10065 JY8QFUQ01BPZ65 productive (see comment) Homsap IGHV3-48*03 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 7 8 14 7.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggattcgccttcaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10066 JY8QFUQ01CQ70Y productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10067 JY8QFUQ01BYUWE productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 146 to 146 in the user submitted sequence), (cause frameshift); gcctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtgGgactctgtgaagggccgattcaccatctcCcagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10068 JY8QFUQ01B25OW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10069 JY8QFUQ01CD5XY No results 10070 JY8QFUQ01B7DJ1 productive (see comment) Homsap IGHV3-7*01 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.17.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gcctctggatTtcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10071 JY8QFUQ01A3PZ4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10072 JY8QFUQ01AM7GI productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10073 JY8QFUQ01CZWZN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 1 8 8 16 8.8.16 [1.17.38.11] CTKDPQQLLEGVNWFDPW in-frame - cctctggattcacctttaggagctatgccatgagttgggtccgccaggctccagggaaggggctagagtgggtctcgtctatcagtggcagtggtgataagacaaagtatgcagattcagtgaggggccggttcaccatctccagagacaattacgacaacacattatatctgcgaatggagggcctgagagccgaggacacggccacatattactgtacgaaagatcctcagcaactgttggaaggggtaaattggttcgacccctggggccagggaaccctggtcaaggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10074 JY8QFUQ01AQXZ4 productive (see comment) Homsap IGHV3-7*01 F (see comment) 693 80.18 174/217 nt 79.72 173/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatacttttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10075 JY8QFUQ01AN9EU productive (see comment) Homsap IGHV3-7*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttactattGggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10076 JY8QFUQ01A87WT unproductive Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGGNGDLDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10077 JY8QFUQ01BPT28 No results 10078 JY8QFUQ01DJVA6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + cctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10079 JY8QFUQ01B015N No results 10080 JY8QFUQ01CYHLK unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYLNL#DYW out-of-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatatttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10081 JY8QFUQ01A572X No results 10082 JY8QFUQ01AVUEZ No results 10083 JY8QFUQ01AUDTZ productive Homsap IGHV3-7*01 F 1045 97.72 214/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - gcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10084 JY8QFUQ01BHJG9 productive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtggcctcatcagcagtggtacttactactggacttggatccggcaggccgccgGgggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10085 JY8QFUQ01CSZEX No results 10086 JY8QFUQ01C62U1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggttttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10087 JY8QFUQ01BIHK2 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 934 91.44 203/222 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [2.17.38.11] CARSAYCGADCYSADYLQHW in-frame - gtctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10088 JY8QFUQ01BW009 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*10 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-7*01 F (see comment) 697 80.56 174/216 nt 80.09 173/216 nt Homsap IGHJ1*01 F 125 71.15 37/52 nt Homsap IGHD1-1*01 F 1 8 8 16 8.8.16 [1.17.37.11] CSRGTTGTTDDSRLFQHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggttttggatgacctgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgttttcgtcaacatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10089 JY8QFUQ01A6VCW productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggctccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10090 JY8QFUQ01C4L8V unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 10091 JY8QFUQ01BMHOE productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10092 JY8QFUQ01BFX7V No results 10093 JY8QFUQ01CR39B unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F (see comment) 700 84.62 165/195 nt 84.1 164/195 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) tgtggtgggtccttcagtggtttctactagagatgcattcgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10094 JY8QFUQ01AUUPD productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10095 JY8QFUQ01C28MT productive (see comment) Homsap IGHV3-48*01 F 995 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggntccagggaaggGggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10096 JY8QFUQ01AAR41 No results 10097 JY8QFUQ01BV26V productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatacctggtccagggcttcttccccca 10098 JY8QFUQ01A8S2Q productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 10099 JY8QFUQ01CBKVX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10100 JY8QFUQ01CPNX4 No results 10101 JY8QFUQ01BOB21 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 804 92.47 172/186 nt 8 8 X 8.8.X [1.17.27.X] null + No rearrangement found ctctggattcagcttcagtagctacagtatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcca 10102 JY8QFUQ01BMNFC unknown (see comment) Homsap IGHV3-13*02 F 83 52.68 59/112 nt 50.89 57/112 nt 8 X X 8.X.X [23.6.X.X] null + No rearrangement found in FR1-IMGT at codon 12 of V-REGION: 'CAGC' (4 nucleotides at position 67 to 70 in the user submitted sequence), (cause frameshift); in FR1-IMGT, from codon 22 of V-REGION: 5 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) tggggaagaagcctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctCAGCgggaagaccttggggctggtcggggatgctggggccgccggatccaactccagtagtaaccagtcatggagccaccagaga 10103 JY8QFUQ01CO0B8 productive Homsap IGHV3-7*01 F 907 92.02 196/213 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [X.17.38.11] CSRHGGYTRLYNQNVYLDYW in-frame + ggattcacatttagcaacttttggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaaaataaacccagacggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgagactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10104 JY8QFUQ01CWGFZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10105 JY8QFUQ01AL6E3 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 17 8.7.17 [1.17.38.11] CARVVTATIYTGSYYFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctatggtgcgtccttcagtgattactcctgggcctggatccgccagTcccccagggaaggggctggagtggattggagagatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgaggcatcatatcaatagacatgtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtatattactgtgcgagagtcgtcacggctacaatttatactgggtcctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 10106 JY8QFUQ01CKPDD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10107 JY8QFUQ01B66MK unproductive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 255 77.27 68/88 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 X X X X.X.X [X.X.29.11] CVKRSKGQQL#YYFENW out-of-frame - stop codons Low V-REGION identity (77,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggaattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctctgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10108 JY8QFUQ01DOOG7 No results 10109 JY8QFUQ01A7F9O unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 106 53.44 70/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10110 JY8QFUQ01ACOUC productive (see comment) Homsap IGHV3-48*04 F (see comment) 786 83.86 187/223 nt 83.41 186/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [3.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); gcctgctggagttcagccatttagtacctattggatgggctgggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10111 JY8QFUQ01BNMSP productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.37.11] CATDSPTGYYAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 159 in the user submitted sequence), (cause frameshift) tctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10112 JY8QFUQ01B13XW productive (see comment) Homsap IGHV1-24*01 F 988 96.24 205/213 nt 95.77 204/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggCaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10113 JY8QFUQ01C1QUY productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDGGSYNRMDLW in-frame + gtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcaaggggctggagtggatggcaattatatggtatgatgggaaaaataaatattatgaagagtccgtgaaggaccgattcaccgtctccagagacaattccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccggaccagccccaaagggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10114 JY8QFUQ01AGVPB No results 10115 JY8QFUQ01AM2IT unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARLRSFGDYP#DVW out-of-frame + stop codons cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactacccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10116 JY8QFUQ01BU8C6 unproductive (see comment) Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgcatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10117 JY8QFUQ01AVFWE No results 10118 JY8QFUQ01BGJJ8 productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10119 JY8QFUQ01BCAAX productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 10120 JY8QFUQ01CGW8W No results 10121 JY8QFUQ01B6JKZ productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10122 JY8QFUQ01DV171 productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 10123 JY8QFUQ01DBY0W unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga 10124 JY8QFUQ01C71OC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggattcaccttcatcagttatggcatgagttgggtccgccaggTttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10125 JY8QFUQ01BE3QC No results 10126 JY8QFUQ01AX5EL productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 97.22 210/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10127 JY8QFUQ01BLXMI productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 973 94.06 206/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD1-26*01 F 1 9 7 12 9.7.12 [2.17.38.11] CARKGMGSTGWDFW in-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctctggtggctccatcagcagtaataactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcataatgggagaaccctcttcaatgcgtccctcaagagtcgagtcaccatatcagtagacaagtctaagagccagttctccctgaagttgaactctgtgaccgccgcggacacggccgtatattactgtgcgagaaaaggaatgggctctaccgggtgggacttctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10128 JY8QFUQ01A2OQJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10129 JY8QFUQ01BF6IL productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAKGGGNGDLDYWG in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaacccctggtcaccgtctcctcagcatcccccgaccagccccaaggttcttgcccgctgagcctcgacagnaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccc 10130 JY8QFUQ01A9XRP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10131 JY8QFUQ01C67DD No results 10132 JY8QFUQ01B13IK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggAactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10133 JY8QFUQ01DGE1E productive Homsap IGHV3-21*04 F 954 93.55 203/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame - ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10134 JY8QFUQ01DBSU6 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 559 73.06 160/219 nt 71.69 157/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*01 F 2 10 7 13 10.7.13 [1.17.38.11] CTRGSLTGTYPSDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (73,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'TCTGAG' (6 nucleotides at position 98 to 103 in the user submitted sequence), (do not cause frameshift); in CDR2-IMGT, from codon 60 of V-REGION: 6 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) ttcggagacgatatatctggagacagtgttacttggaactggatcaggcagTcccccagggagggggcttgagtggctcgggcgtatctttcacaggTCTGAGtggcataccgactacttggcgtctgttagaggccgaatctccatggatgtcgacacgtccaagaaccacttcaccctgcagctccgctctctgactcccgacgacacggctacatatttctgtacaagaggctctctaactgggacatatccttctgaccactggggtctggggaccccagtgaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10135 JY8QFUQ01CNWHA unproductive (see comment) Homsap IGHV3-7*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKNRI*ITLAGTA#FDYW out-of-frame - stop codons in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtggctattggatgagttgggtccgccaggctccagGggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcaaaaaatcggatataaataacattggctggcacggcctatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10136 JY8QFUQ01BQX07 No results 10137 JY8QFUQ01COS53 productive Homsap IGHV3-72*01 F 961 92.79 206/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10138 JY8QFUQ01C70M7 productive (see comment) Homsap IGHV3-7*01 F 733 95.06 154/162 nt 94.44 153/162 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 0 11 8.0.11 [1.17.27.11] CAKGGGNGDLDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 55 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 10139 JY8QFUQ01CN6A2 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 172 57.53 84/146 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccggggaaggggctacagtgggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 10140 JY8QFUQ01CRPO4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGICYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); tagcctctggattcaGcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtatatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10141 JY8QFUQ01C8TZM unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaagggtcttcccgctgagcctcgaccagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 10142 JY8QFUQ01C0F74 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 10143 JY8QFUQ01A3FLZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10144 JY8QFUQ01B21SF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10145 JY8QFUQ01CTRZY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10146 JY8QFUQ01CZKTN productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 10 7 11 10.7.11 [1.17.38.11] CAGGEDPFKVRHW in-frame + tctctggtggctccttttctaatcatggttaccactgtagttggctccgccagttcccagggaaggacctggagtggattgcctacatctattacactgggagcaccgagtataacccgtccctcaggagtcgagttgccatatcagtggacacgtctgggaaccagtgttccctggagttgaactctgtgagtgccgcggacacggccgtctattactgtgcgggaggcgaggatcccttcaaagttcgacactggggccagggaacccgggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10147 JY8QFUQ01BFEHI productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 813 86.92 186/214 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVGVGVGSSVSFQYW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactgtcaataacaactacatgggttgggtccgccaggctccagggaaggggctggagtgggtctcgactatttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacactttttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgtgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10148 JY8QFUQ01B9QQ1 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 259 59.28 115/194 nt 58.76 114/194 nt 8 8 X 8.8.X [1.16.30.X] null + No rearrangement found Low V-REGION identity (59,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10149 JY8QFUQ01DJU8W No results 10150 JY8QFUQ01BXIV3 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 872 87.5 196/224 nt 85.71 192/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [2.16.38.11] CNADVPSPLAQNDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 61 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) gcctctgggttcGattttcagtgatgcctggatgagttggtccgccaggctccagggaaggctctggagtgggttgcccgtataaaaacttttggtgAacggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcGaaaaaaaaggctgtatctgcaaatggacagcctgagaatcgaggacacagccaagtattactgcaacgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10151 JY8QFUQ01B8YBT No results 10152 JY8QFUQ01CP6NE No results 10153 JY8QFUQ01A2E3L No results 10154 JY8QFUQ01BY2RR productive (see comment) Homsap IGHV3-9*01 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [2.17.38.11] CGRIAKPGLGALDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gggcgttggattcacttttaatgGaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10155 JY8QFUQ01DNHX4 No results 10156 JY8QFUQ01BST4Q No results 10157 JY8QFUQ01CBBPX productive (see comment) Homsap IGHV3-74*03 F 846 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcacGtttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10158 JY8QFUQ01DOUFW productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10159 JY8QFUQ01BF7RI unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10160 JY8QFUQ01BQZYK productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 922 90.22 203/225 nt 89.78 202/225 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 15 8.10.15 [2.17.38.11] CTTDRRGLSIPPQFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggccgtataaaaaacaaagctatgggtgagacaacagacttcgctgcacccgtgagaggcagattcagtatctcaagagatgattcaaaaaatacactgtatctgcacatgagtggcctgaaaaccgagGgacacagccgtctattattgtaccacagatcggcggggtttgtctataccacctcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10161 JY8QFUQ01B40GM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10162 JY8QFUQ01BXD0I productive Homsap IGHV4-39*03 F 919 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10163 JY8QFUQ01CM17V productive (see comment) Homsap IGHV3-33*03 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 7 12 8.7.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10164 JY8QFUQ01C05EA No results 10165 JY8QFUQ01A1RAE productive Homsap IGHV3-30*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CPKTGPGHSSPFDYW in-frame + ctctggattcaccttccgaagttatgatctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcatttatttcaaacgatggaagtgacacagactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaagacgctatatctgcaaatgaacagcctgagagttgaggacacggctgtgtattactgtccgaaaaccggccccggtcatagcagcccctttgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10166 JY8QFUQ01A2C1P productive (see comment) Homsap IGHV3-48*01 F 972 94.47 205/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-2*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARGRCSSSNCKPLYGEFGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtgggAtttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaagacacggctatatattactgtgcgcgaggaagatgtagtagttccaattgtaagccactttacggtgaatttgggtattggggccagggaaccccagtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10167 JY8QFUQ01C5UF8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaacttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10168 JY8QFUQ01AFE74 productive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10169 JY8QFUQ01DCDMJ unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNGADF# out-of-frame - tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttgggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10170 JY8QFUQ01A921B unproductive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [0.17.38.11] CARVIRTNWL#PL out-of-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctgggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 10171 JY8QFUQ01AR8K0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARRTITAAGRGDDYW in-frame - gcctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10172 JY8QFUQ01BYPPR No results 10173 JY8QFUQ01AIJHN No results 10174 JY8QFUQ01A6JS9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10175 JY8QFUQ01C7QCP No results 10176 JY8QFUQ01DGUMB No results 10177 JY8QFUQ01DHRFR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'CATCC' (5 nucleotides at position 139 to 143 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 164 to 164 in the user submitted sequence), (cause frameshift); tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgccagggccggttgcgatcCATCCtccagagacaattcgaagaaTcacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10178 JY8QFUQ01A11F6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10179 JY8QFUQ01BPGLO No results 10180 JY8QFUQ01CEIJB unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDQRSGDA#EAFDIW out-of-frame + stop codons ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaaggtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10181 JY8QFUQ01C0K2G No results 10182 JY8QFUQ01CUANG productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 939 93.46 200/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARGWLTAADTGVASGHDWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcaccagctactatatgcactggatacgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtaccacaaggtacgcacagaagttccagggcagagtcttcatgaccagagacacgtccacgagcacagtccacatggaggtgaacggcgtaagatctgacgacacggccgtgtattactgtgcccgagggtggctgacagcagctgataccggggtggcgtcagggcacgattggttcgactcctggggccagggaaccctggtaaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 10183 JY8QFUQ01B07O4 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttgcctcagcatcccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccga 10184 JY8QFUQ01ALWT0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1030 97.69 211/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame - tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10185 JY8QFUQ01C9SSW No results 10186 JY8QFUQ01AZHT9 productive (see comment) Homsap IGHV3-7*01 F (see comment) 707 80.73 176/218 nt 80.28 175/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatactTttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10187 JY8QFUQ01CMWLP productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10188 JY8QFUQ01C5L8H productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10189 JY8QFUQ01DHKZJ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt 94.57 209/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtaatagtttctactAggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10190 JY8QFUQ01A5OYB No results 10191 JY8QFUQ01AZOIS productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 609 96.92 126/130 nt 96.15 125/130 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 7 X 15 7.X.15 [1.X.35.11] CTRELRLAAARDGVDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 84 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift) ctctgggttcaccgtcagtagcaaagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10192 JY8QFUQ01DI435 No results 10193 JY8QFUQ01BNTHD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10194 JY8QFUQ01AZ89E productive Homsap IGHV4-61*02 F 1028 96.38 213/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARAPSYTNSHQHCDYW in-frame + tctctggtggctccatcaacagtggtagttactactggagttggattcggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattattgtgcgagagctccctcttataccaactcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatcccgacagccccaaggtcttcccgctgagcctcganagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 10195 JY8QFUQ01DKUXC No results 10196 JY8QFUQ01A63GT unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.17.38.11] CARGAPFS**C in-frame + stop codons ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10197 JY8QFUQ01DIBNC productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtGgggagcaccaactacaaCcccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccctatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccctgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactcag 10198 JY8QFUQ01CQCPA unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGAEAGL#DYW out-of-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10199 JY8QFUQ01B8E5L productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 10200 JY8QFUQ01CKO0V No results 10201 JY8QFUQ01CBSKZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F 766 93.64 162/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggattcaccttcagtgactattacatgggctggatccgccaggctccagggaaggggctggagtgggtttcatccattagtaatagtgctagtaccatgtacctggcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgcatctgc 10202 JY8QFUQ01ALS9D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10203 JY8QFUQ01BFWUZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaac 10204 JY8QFUQ01AGZTV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10205 JY8QFUQ01BM96X productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDWPSSGWSHFEAW in-frame + ctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10206 JY8QFUQ01A8BAL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10207 JY8QFUQ01CI0IM No results 10208 JY8QFUQ01DEIA7 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10209 JY8QFUQ01A7Z2B productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacatgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10210 JY8QFUQ01BH96D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10211 JY8QFUQ01A1OLP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10212 JY8QFUQ01B7YIT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10213 JY8QFUQ01A1OIA No results 10214 JY8QFUQ01CLBGL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - gcctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtaagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10215 JY8QFUQ01B9KF0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 10216 JY8QFUQ01CAQNJ No results 10217 JY8QFUQ01DK1AF unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 951 92.73 204/220 nt 91.36 201/220 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.17.38.11] CARPAFSGSGTYRP#DGFDVW out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); ggtttctggatacagcCtttaccaattactggatcggctgggtgcgccaggtgcccggCaaaaggcctggagtggatCggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagctttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10218 JY8QFUQ01CEV8W unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDLYGADDL# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 10219 JY8QFUQ01AGRP6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 13 8.8.13 [1.17.38.11] CATGAGNWNYIFNYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtggtttttGatatatactacgcggattcagtgaagggccgagtcaccatctccagagacaacgccaagaattcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacatttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10220 JY8QFUQ01AMBE4 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 271 67.97 87/128 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found Low V-REGION identity (67,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10221 JY8QFUQ01BFV12 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgcttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 10222 JY8QFUQ01AKRWC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10223 JY8QFUQ01CIF2W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 10224 JY8QFUQ01AVT39 productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 10225 JY8QFUQ01ABWTO No results 10226 JY8QFUQ01AGX2K No results 10227 JY8QFUQ01A4OCK unknown (see comment) Homsap IGHV3-74*03 F 126 51.21 106/207 nt 8 6 X 8.6.X [1.17.36.X] null + No rearrangement found ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10228 JY8QFUQ01ABDY1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10229 JY8QFUQ01CZVW2 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 963 94.01 204/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + ctctggattcacctttgatgattttggcatgagttgggtccgccaagttccagggaaggggctggagtgggtcgctggtatcagttggaatggaggcaaaacaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcattgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10230 JY8QFUQ01B0GPK productive Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD6-13*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARERQLNNGMDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggcccacataaagcaagatggaagtgtcaaataccaagtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagagcggcagcttaataacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10231 JY8QFUQ01DSJLM unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.15 212/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [2.17.38.11] CARLGARFGD#DYW out-of-frame - stop codons in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10232 JY8QFUQ01C1UC1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSG## out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgTtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10233 JY8QFUQ01ADRL4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggGAagggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10234 JY8QFUQ01CSA9Y productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctccatcatcagagacagtgcctactggggctggatccgccagccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10235 JY8QFUQ01BIKPK productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10236 JY8QFUQ01CCVD9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 634 76.85 166/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (76,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10237 JY8QFUQ01COMBA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgGgggagggggctggagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10238 JY8QFUQ01DME6J productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcaatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 10239 JY8QFUQ01A6K87 unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - stop codons in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggtgactccgtcagcagtgataactagtggaGgttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10240 JY8QFUQ01BJCRY No results 10241 JY8QFUQ01B76II productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10242 JY8QFUQ01CFMZ4 No results 10243 JY8QFUQ01CC6BC productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 973 92.11 210/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [2.17.38.11] CARGGDYYDSGGLDYW in-frame + tctccgggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 10244 JY8QFUQ01CPBOV productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.37.11] CARGDGYNFGGLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) ctatggattcaacttcattggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatctttatgcagactccgtgagggccgatccatcatttccagagacgattctaaaagaacactgtttctccaaatggacaacctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10245 JY8QFUQ01APAZK No results 10246 JY8QFUQ01AU2HD productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10247 JY8QFUQ01DNPPJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10248 JY8QFUQ01BGGO2 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CVKDLGSYGSPWRAYYYYGMDAW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggattcGaccctcaacagcCaatggcatgcactgggtccgccagactccagacaaggggctggagtgggtggcagtgatttcatatgatggaaatgataaatactatggagatgcagtgacgggccgattcaccatctccagagacacttccaagaacacagtatatctggagatgtacagcctgagacctgaggacacggctgtgtattactgtgtgaaagatcttgggagttacggtagtccttggcgcgcctactattactacggcatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10249 JY8QFUQ01CMMRS No results 10250 JY8QFUQ01CVL1P productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ1*01 F 215 90.38 47/52 nt Homsap IGHD5-12*01 F 3 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); cctctgacttaaTcggtcagtgacaattaGcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacggttcccagaacacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtatttttgtgcgagtggtggttattcgggctcgggtgaatatttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10251 JY8QFUQ01BIM6Q productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1071 99.54 216/217 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame + ttctggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10252 JY8QFUQ01DJHPK No results 10253 JY8QFUQ01DNM3T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 917 92.09 198/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAKGYSSGWYDFDCW in-frame + ctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10254 JY8QFUQ01A4V0H No results 10255 JY8QFUQ01BK76H productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 917 90.18 202/224 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [3.17.38.11] CAKEEFDTGWTQPGDW in-frame - gtgcagcctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10256 JY8QFUQ01CO056 No results 10257 JY8QFUQ01ABPW8 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcgacgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10258 JY8QFUQ01A4J2Q productive (see comment) Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [2.17.38.11] CARDGRGGDLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); agtgtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10259 JY8QFUQ01BTATM unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 85 80.77 21/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctctggattcagcgtcaacaacaaca 10260 JY8QFUQ01BHA3Z No results 10261 JY8QFUQ01BYQCI No results 10262 JY8QFUQ01DT4IK productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 17 8.8.17 [0.17.38.11] CASDREDTAMITAESFNIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); tggaggcaccttcagtagacatgctatcaactgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcaaccccaCtccttcatacaaccaaatatgcacagaggttccagggcagagtcacatttaccgcggacgaatccacggccacagtctacatgcaactgagcagcctgggatctgaagacacggccgtctattattgtgcgagcgatcgggaagatacagctatgattaccgcggagagttttaatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcctgcctggtccagggcttcttcccccag 10263 JY8QFUQ01C2EJV productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccattggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 10264 JY8QFUQ01BGKVU No results 10265 JY8QFUQ01AZUCW No results 10266 JY8QFUQ01B507I No results 10267 JY8QFUQ01C5VRD No results 10268 JY8QFUQ01AJVZE unknown (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10269 JY8QFUQ01AEIW4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaaatgaacgcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10270 JY8QFUQ01CNH24 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt 91.59 196/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAARIDSGHYWNAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'A' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); tggatacagtttcaccaactactggatcggctCgggtgcgccagatgAcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaagGgccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10271 JY8QFUQ01DBH5A productive (see comment) Homsap IGHV1-2*04 F 925 92.96 198/213 nt 92.02 196/213 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 14 8.8.14 [0.17.37.11] CTRDTSLDNGAALDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tggatacaccttcaccgactactatatgcactgggtgcgacagGgccccaggacaagggcttgagtggatgggatggatcaaccctaaaagtggcggcacaaattatgcacggaagtttcaggctgggtcaccatgaccagggacacatccatcaacactgtctacatggagttgagcaggttgaaatctgacgacacggccatttattactgtacgagggatacttctttggacaacggagccgctcttgatatttggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10272 JY8QFUQ01BMOQ4 productive Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10273 JY8QFUQ01BLHGO unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactGggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10274 JY8QFUQ01BIGVU unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 8 21 8.8.21 [1.17.38.11] CAKDPLYYDFVWGSYRYQSLDY* in-frame + stop codons ctctggattcacctttaccgcctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactataagtggtagtggtggtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcccctgtattatgatttcgtttggggaagttatcgttatcaatcccttgactactgaggccagggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10275 JY8QFUQ01DFPT2 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 872 89.35 193/216 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [2.17.38.11] CARDRQSWR#DSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacncagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctggcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10276 JY8QFUQ01C6DVB productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame - ctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10277 JY8QFUQ01A0LMF No results 10278 JY8QFUQ01AHVFU No results 10279 JY8QFUQ01B92XS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKLGWQLLLG#FFDYW out-of-frame + tctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag 10280 JY8QFUQ01DLY9L No results 10281 JY8QFUQ01AO340 No results 10282 JY8QFUQ01DXFVY unproductive Homsap IGHV3-48*01 F (see comment) 769 84.26 182/216 nt 82.87 179/216 nt Homsap IGHJ1*01 F 125 71.15 37/52 nt Homsap IGHD5-12*01 F 1 8 7 X 8.7.X [2.17.37.11] CSRDGRRGYDLDS## out-of-frame - Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 94 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagaAttctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcgagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctgggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10283 JY8QFUQ01BH18R productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10284 JY8QFUQ01BO6JQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 887 89.91 196/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 17 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) gcctcctggattcaccCTttgggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10285 JY8QFUQ01ANK2A No results 10286 JY8QFUQ01B9WVJ productive Homsap IGHV3-21*04 F 954 93.55 203/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaattcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagga 10287 JY8QFUQ01BRXEL No results 10288 JY8QFUQ01BLWC3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 952 94.37 201/213 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [X.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10289 JY8QFUQ01AW74R unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 640 85.55 148/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgc 10290 JY8QFUQ01CXKT7 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10291 JY8QFUQ01CZJSX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.16.38.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) ctctggattcacccttcgcagatatggcatggcgtggtccgccaggctccggGggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgCtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctcgtccagggcttcttccccca 10292 JY8QFUQ01AYEWF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10293 JY8QFUQ01CPINH No results 10294 JY8QFUQ01AH8WJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 10295 JY8QFUQ01AF6K3 productive (see comment) Homsap IGHV3-9*01 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [0.16.38.11] CARTYGDHDGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) tggattcacctttgacgactatggcatgcactggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10296 JY8QFUQ01B1EKF productive (see comment) Homsap IGHV3-69-1*01 P 915 92.89 196/211 nt 92.42 195/211 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 11 8.7.11 [1.16.38.11] CARSGSGSHLDYW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 77 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactacagcatgaactgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10297 JY8QFUQ01C48XK productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10298 JY8QFUQ01AE2LT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10299 JY8QFUQ01CXEQL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD5-18*01 F 3 8 8 12 8.8.12 [1.16.38.11] CVKDDGDNYGFHHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 78 in the user submitted sequence), (do not cause frameshift) cctctggattcgcctttagcagctgtgccttgggctgggtccgccaggctccagggaaggggctggagtggatctcaggtagtggtagtagtgatagtccatattatgcagactccgtgaagggccgcttcaccatctccagggacaattccaggaacacaatctatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgtgtgaaggatgacggagacaactatggttttcaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 10300 JY8QFUQ01DCZ0B No results 10301 JY8QFUQ01BUWTQ No results 10302 JY8QFUQ01DR4UR productive (see comment) Homsap IGHV4-61*03 F 880 88.74 197/222 nt 88.29 196/222 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [2.17.38.11] CTRHPKSNVEGDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tgccctggtggctccgtcagcaGgtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10303 JY8QFUQ01BLHK3 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10304 JY8QFUQ01CU6ZB No results 10305 JY8QFUQ01CJBIY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGFW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10306 JY8QFUQ01C28AG unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F (see comment) 215 63.71 79/124 nt 8 8 X 8.8.X [1.17.7.X] null + No rearrangement found Low V-REGION identity (63,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10307 JY8QFUQ01CRJU3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10308 JY8QFUQ01AMPYU productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10309 JY8QFUQ01BYP3T No results 10310 JY8QFUQ01AP0OV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10311 JY8QFUQ01AR68Q unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 840 88.32 189/214 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [0.17.38.11] CTRVGTFNWF#PW out-of-frame - tggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10312 JY8QFUQ01AJ3A7 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 10313 JY8QFUQ01AS6WG No results 10314 JY8QFUQ01AH911 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 993 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARPGVGASSFIDFW in-frame + tggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10315 JY8QFUQ01B7IPI No results 10316 JY8QFUQ01AXJRF productive (see comment) Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10317 JY8QFUQ01BBMXO productive Homsap IGHV3-64*04 F 894 91.12 195/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10318 JY8QFUQ01BS22J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 10319 JY8QFUQ01AJVK8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggGaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10320 JY8QFUQ01AULWJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtggatctcatccattagtagtagtggtttttatatatactacgcggactcagtgaagggccgagtcaccatctccagagacaacgccaagaactcgctatctctgcaaatgagcaacctgcgagccgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10321 JY8QFUQ01DUGP5 productive (see comment) Homsap IGHV4-61*02 F (see comment) 600 75.0 165/220 nt 74.55 164/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 10 7 15 10.7.15 [1.17.37.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcaggccgccgggaaggggctggagtgggtcgggcgtgtctatatgactggctatgtcgagaacaatccatccctctccgggcgtctctccatgtcgattgacacggcgaagaatcagtttctatgacattgacttctgtgaccgccgcagacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10322 JY8QFUQ01DV2OJ No results 10323 JY8QFUQ01DES1Q productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 592 91.49 129/141 nt 90.78 128/141 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 3 8 X 13 8.X.13 [1.2.35.11] CARGRYGDQVTWDYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctataccttgagttggatgcagtgaagggccgattcaccatttccagagacaacgccaagaactccctctctctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagaggtcgctacggtgaccaagtaacctgggactactggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10324 JY8QFUQ01DRLVX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 90.52 191/211 nt 89.1 188/211 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [X.17.37.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) ggatcacctttagtagatttgccatgacctgggtccgtcaggctccagGgcaaggggctggagtgggtCgtcaactattcattataatggtgataacacatactacgcagactccgtgagggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10325 JY8QFUQ01DKQM5 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ6*01 F (see comment) 106 64.41 38/59 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKVDSSSAWDY# out-of-frame + Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcaagtttcatgaatatgccatgatctgggtccgccaggctccaggcaagggtccggaatgggtctcgtctattagtagtactagtaaatacatctattatgcacagtcagtggagggccgattcaccatctccagagacgacgccgagaacgcactgttcctccagatgagcagcctgagtgtcgacgacacggctatctattactgcgcgaaagtcgatagcagttcggcctgggactattggggcccgggaacctggtcaccgtctcttcagcatccccgaccagccccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10326 JY8QFUQ01DEKM7 productive (see comment) Homsap IGHV3-72*01 F 961 92.79 206/222 nt 92.34 205/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.16.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10327 JY8QFUQ01CJWXV No results 10328 JY8QFUQ01CCEY2 productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10329 JY8QFUQ01AXGG1 No results 10330 JY8QFUQ01BGPMP productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 10331 JY8QFUQ01CGQYY productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10332 JY8QFUQ01BEBC3 unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARDFWRFLQFSG#YW out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10333 JY8QFUQ01CAHIJ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 944 91.52 205/224 nt 90.62 203/224 nt Homsap IGHJ4*02 F 184 90.91 40/44 nt 8 10 6 8.10.6 [1.17.38.11] CTTESAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccagggaaAggggctggagtggcttggccgtattaaaaggaaagttgatggtgagacaacagactacgctgcatccgtgaaagGgcagattcaccatctggagagatgactcaaaaaacactctatatctgcaaatgaacagcctggaacccgaggacacagccgtatattattgtaccactgaatctgcctattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10334 JY8QFUQ01CVA0Q unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.16.38.11] CARKRVPGGNFLWDY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaagggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagaggcaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttatgggactactgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtggaactcag 10335 JY8QFUQ01AJCO3 No results 10336 JY8QFUQ01C3IL3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10337 JY8QFUQ01CNEDV No results 10338 JY8QFUQ01C027H unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 670 93.42 142/152 nt 8 8 X 8.8.X [1.17.16.X] null - No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaaaggccgattcaccatctccagagacaatg 10339 JY8QFUQ01CLZBQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARDILGATRFDYW in-frame - ctctggattcaccttcagcagctatgccatgagctgggtccgccaggctccagggaagggcctggagtgggtctcagctattagtggtattggtgggagtacattctacgcagactccgtgaagggccggttcaccatcaccagagacaattccaacaacacgctgtttctgcaaatgaatagcctgagagccgaggacacggccatatattactgtgcgagagatattctgggagctactcggtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10340 JY8QFUQ01CGIC8 unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 254 69.64 78/112 nt 8 8 X 8.8.X [0.17.4.X] null - No rearrangement found Low V-REGION identity (69,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 10341 JY8QFUQ01CL7VE productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.16.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaaggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10342 JY8QFUQ01C97W1 productive Homsap IGHV3-30*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDSW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcttcgatagttatgctctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactctgtgaggggccgatccatcatttccagagacgattctaaaagaacactgtttctccaaatggacaacctgagagctgaggacacagctgtctattattgtgcgaggggagatggctacaatttcgggggattagactcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10343 JY8QFUQ01A4C55 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame + tctctggtgactccttcagaactcactactggagttggattcgacagcccccggggaggagattggaatggattggcaatatatattatattgggaccaccaactacaacccctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgagctgcctggtcaaggactacttcccccgaaccggtgacggtgtcggtggaactca 10344 JY8QFUQ01CL4UJ productive (see comment) Homsap IGHV3-11*01 F (see comment) 687 80.37 172/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [1.17.37.11] CVRDRSRGIADPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 166 in the user submitted sequence), (cause frameshift) tctggattcaccttcactgactattggatgagttgggtgcgtctgaccccagggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaatttagtcttttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10345 JY8QFUQ01CCRJF productive (see comment) Homsap IGHV3-11*01 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 97 to 99 in the user submitted sequence), (do not cause frameshift); gcttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10346 JY8QFUQ01AJ2WR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame - gcctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10347 JY8QFUQ01A2WIH No results 10348 JY8QFUQ01BDGF0 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10349 JY8QFUQ01A1MP0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 7 8 19 7.8.19 [2.17.38.11] CTKDYPDGRLLNQVRPFFDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) gcctctggatacagtttaacagttatgccatgacttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10350 JY8QFUQ01A287O productive Homsap IGHV3-13*01 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10351 JY8QFUQ01CYR1Z productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 890 90.7 195/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 7 14 8.7.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10352 JY8QFUQ01BG6BT unproductive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPVSSVTTGEGR#YW out-of-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccccgtttcatcggtgactactggggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccagcatggagacgtggtcgtcgcatgcctggtccagggcttcttccccca 10353 JY8QFUQ01CEGMR unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1095 100.0 220/220 nt 99.09 218/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [0.16.38.11] CTKCSVTIYL#FDYW out-of-frame - stop codons in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctggattcacctttGggtgattatgctatgagctggttccgccaggctccaggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttaccttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10354 JY8QFUQ01CHJER productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10355 JY8QFUQ01AYQK1 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10356 JY8QFUQ01CR8FR No results 10357 JY8QFUQ01CV3S6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10358 JY8QFUQ01BCLNK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10359 JY8QFUQ01AHDAC unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10360 JY8QFUQ01CJAF2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CAKEEVPNDYW in-frame - ctctggattcacctttagcaatgctgccatgacgtgggtccgccaggctccagggaaggggctagagtgggtctcaggtattagtattagtggtgatagaacatattacgcagactccgtgaagggccggttcaccatctctagagacaattccaagaataccgtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10361 JY8QFUQ01ASTX9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10362 JY8QFUQ01AX2K6 No results 10363 JY8QFUQ01AJ17C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10364 JY8QFUQ01B4ODW productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 825 86.36 190/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame + ctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagtccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10365 JY8QFUQ01BKPFE unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKN*GVGDG##WYFDFW out-of-frame + stop codons in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaattagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10366 JY8QFUQ01DT2D1 productive (see comment) Homsap IGHV4-4*08 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 7 15 8.7.15 [1.16.38.11] CARGDGSLNSYGSLGNW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagtagttcctactggagctggatccggcagccgccgggaagggactggagtggattgggcatgtctataccagtgggagcaccgactacaacccctccctccggagtcgagtcaccatatcagtggacacgtcaaagaaccagttctccctgaagctgacctctgtgaccgccgcagagacggccttatattactgtgcgagaggggacgggagtttgaactcctacgggagtcttggcaactggggccagggaaccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10367 JY8QFUQ01BS2Q3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame + ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10368 JY8QFUQ01AGYKQ unproductive Homsap IGHV3-48*04 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CSRHGGYTKLYNQM#YLDYW out-of-frame + cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgaaactctacaatcaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10369 JY8QFUQ01AX3JG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame - cctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10370 JY8QFUQ01AQS6C unproductive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDLVGSIG#W out-of-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10371 JY8QFUQ01BWT8S No results 10372 JY8QFUQ01BRDXB productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - cctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10373 JY8QFUQ01DIQXW No results 10374 JY8QFUQ01CRJQG productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 968 92.07 209/227 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 3 10 9 19 10.9.19 [1.17.38.11] CARSSRRDRLSDRNYYELDFW in-frame - tctccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatactacaggtccaaatgggatactgattatgcggcgtctgtgaaaagtcgaataaccctcaccccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattattgtgcaagatcttccagacgcgatcgtttgtctgataggaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10375 JY8QFUQ01CNGWQ productive (see comment) Homsap IGHV3-11*01 F 984 95.79 205/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtGgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10376 JY8QFUQ01B65GE No results 10377 JY8QFUQ01B49LV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10378 JY8QFUQ01BU1EN productive (see comment) Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 10379 JY8QFUQ01AN6Q8 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 921 90.58 202/223 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame - ctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10380 JY8QFUQ01B7N1M unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 113 50.46 110/218 nt 50.0 109/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); tatttggattcaagtttagtaggtaGtgggatgaggtgggtccgccaggctccagggaaggggctggagtgggtggccgacgtactctatgttacgactgtggatctctgtgcgagaagtagcagttggttttacctgatatttcgcggaactacgatttgggcgtctggggccaagggactccggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10381 JY8QFUQ01CTMXD No results 10382 JY8QFUQ01DFUVA productive Homsap IGHV4-61*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + ctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 10383 JY8QFUQ01C55RD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 746 82.79 178/215 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found Low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10384 JY8QFUQ01DKDMJ unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 10385 JY8QFUQ01AWDNT No results 10386 JY8QFUQ01DBUXH productive Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*03 F or Homsap IGHV3-71*01 P 165 68.35 54/79 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 X X 19 X.X.19 [X.X.26.11] CATDGVGSTVKLMVMGPFDFR in-frame - ctctggattcgtctttaacaactatgccatgggctggatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10387 JY8QFUQ01CHGTF unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKTTMTSVT#DWFDPW out-of-frame + in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); ctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgccctgcctgggtccaggggcttcttcccccag 10388 JY8QFUQ01CJOZ9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10389 JY8QFUQ01BBYYE unknown (see comment) Homsap IGHV3-7*03 F (see comment) 756 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggcGtggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10390 JY8QFUQ01CF1BE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.38.11] CAKERDNNVLPVDSW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgaggggccggttcaccgtctccagagacaatttcaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcgttctttccccca 10391 JY8QFUQ01DRV57 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + gtctggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10392 JY8QFUQ01BDYMQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 757 82.65 181/219 nt 81.74 179/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 10 8.8.10 [2.16.38.11] CAKDDSAGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctccggattcatcttcagtgccgcttggatggagtgggtccgccaagttccagggcagggctcgtgtgggtcgcgcgtatcgagagtagtggcagcggcacacgttTacgcggactacgtgaagggccgattcaccgtctccagagacaacgccatgaacatagtgtatcttcaaatgaattctctgactgccgaggacacgggtgtgtattactgcgcaaaggatgattcggccggccttgaccattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10393 JY8QFUQ01DQWIK No results 10394 JY8QFUQ01DRVNJ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) cctctggattcaccCtttggttattatggcatgactgggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10395 JY8QFUQ01A7A9E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctttatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10396 JY8QFUQ01AH5MI productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 669 79.44 170/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame + Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacatatttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10397 JY8QFUQ01BF80N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10398 JY8QFUQ01CB8PZ unproductive (see comment) Homsap IGHV4-61*01 F 942 92.27 203/220 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CTRGAVHL*QPV# out-of-frame + stop codons ctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaggggggcagtacacttatgacagcccgtggggacaggggacccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10399 JY8QFUQ01BTJGP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggngccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10400 JY8QFUQ01CCU9E unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10401 JY8QFUQ01B756E No results 10402 JY8QFUQ01BJG4M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10403 JY8QFUQ01C7QLL productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10404 JY8QFUQ01DLIBX unproductive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGDSGWDYY#HW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgacactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10405 JY8QFUQ01BRKFS productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 963 92.04 208/226 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 3 10 9 19 10.9.19 [1.17.38.11] CARSSRRDRLSDRNYYELDFW in-frame - ctccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatactacaggtccaaatgggatactgattatgcggcgtctgtgaaaagtcgaataaccctcaccccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattattgtgcaagatcttccagacgcgatcgtttgtctgataggaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10406 JY8QFUQ01BOU6G productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10407 JY8QFUQ01DJL36 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 10408 JY8QFUQ01AH02C productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10409 JY8QFUQ01AF6EZ productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10410 JY8QFUQ01CBFGR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10411 JY8QFUQ01CAAF5 productive Homsap IGHV3-21*04 F (see comment) 647 78.14 168/215 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [0.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10412 JY8QFUQ01BGSKW No results 10413 JY8QFUQ01BQ3IH unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactantgggggcgaggggaaccctgattttccgnctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10414 JY8QFUQ01AE5XE productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 10415 JY8QFUQ01AQAEH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYSFDYW in-frame + ctctgggttcacctttgcccactttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtggtgatgattccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactcctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10416 JY8QFUQ01BMOB5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 10417 JY8QFUQ01BJMI5 productive Homsap IGHV1-2*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARVWGTGVGYLDYW in-frame + tggatacaccttcaccgcctactatatacactgggtgcgacaggcccctggacaaggacttgaatggatgggattgatgaaccctaatagtggtggcacaatatacgcgcagaagtttcagggcagggtcaccatgaccagggacacgtccgtcgacacagcctacatggagttgagcaggctcaaatctgacgacacggccatttattattgtgcgagagtctggggtacgggagtcggctaccttgactactggggccagggaacccgggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10418 JY8QFUQ01BDDDQ No results 10419 JY8QFUQ01CR6PP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame + ctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10420 JY8QFUQ01CDV3C productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccGttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10421 JY8QFUQ01DDTVS unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt 99.53 214/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccCgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 10422 JY8QFUQ01DC4V0 No results 10423 JY8QFUQ01CEZMT productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + cgtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10424 JY8QFUQ01BFZEE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.37.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaattcctatnccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10425 JY8QFUQ01BPYPO productive Homsap IGHV3-11*01 F 846 88.02 191/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIKLGDWCFDLW in-frame - ctctgaaatcaccttcagcgaccactacatgagctggatccgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10426 JY8QFUQ01BFTGY productive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10427 JY8QFUQ01ADBWF No results 10428 JY8QFUQ01AHOM5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); aatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10429 JY8QFUQ01BTFSH No results 10430 JY8QFUQ01DF0WH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - ggcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10431 JY8QFUQ01BLA2V productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 869 88.99 194/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.16.38.11] CARDSGSSDYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gcctctggattcagGttttagttcttatggcatgaactgggtccgccaggctccatgggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10432 JY8QFUQ01AO0RN No results 10433 JY8QFUQ01ALQU4 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 10434 JY8QFUQ01DGLOZ No results 10435 JY8QFUQ01CJ5D5 No results 10436 JY8QFUQ01AKZ0I productive (see comment) Homsap IGHV4-39*03 F 937 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 6 17 9.6.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) tctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10437 JY8QFUQ01CJ990 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.16.38.11] CARDTLEVVSNMDDAFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10438 JY8QFUQ01DIRRZ productive Homsap IGHV4-34*03 F (see comment) 750 83.57 178/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRLDAWEVSDHW in-frame + Low V-REGION identity (83,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgacgatgggtcctgtagagagtgcttctggagttggatccgccagtccccagggaagggtctggagtggattggggacgtcaattatagacgaggcgtcgactacaacccgtccctcaagagtcgagtgaccatatcattggacacgtccaacaaacaagtctccctgagtctgagttctgtcaccgccgcggacacggccatgtattattgtacgcgagggcgattagacgcgtgggaagtatcggaccactggggccagggaaccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 10439 JY8QFUQ01COD4T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa 10440 JY8QFUQ01BWHU4 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1072 96.93 221/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - atctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagatgctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10441 JY8QFUQ01AWLUJ unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 934 91.44 203/222 nt 90.99 202/222 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD3-22*01 F 3 8 9 X 8.9.X [1.17.38.11] CATDRPYYKNAAGRLWYYYGMDV#W out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatgggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgttttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10442 JY8QFUQ01BO5QJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 15 7.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 10443 JY8QFUQ01DDY8Y productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame - tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10444 JY8QFUQ01CZQKG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame - cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10445 JY8QFUQ01BLZXE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10446 JY8QFUQ01CI9HQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + ctctggattcagtttcagagactatgccatgagttgggtccgccaggctccagggaagggactggagtgggtctcagcaattagtggaactggtcttaccacatattacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagccctggtctccgtctcctcagcatccccgaccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10447 JY8QFUQ01DDYTC productive (see comment) Homsap IGHV3-7*01 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'CT' (2 nucleotides at position 178 to 179 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagaCTgaaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctccgtcaccatccctgacccagccccaaggtcttccgctgcagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10448 JY8QFUQ01CHRC3 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + ttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggctcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg 10449 JY8QFUQ01BTRS8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10450 JY8QFUQ01B8D1W productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 782 85.12 183/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame - tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10451 JY8QFUQ01AH46J productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFV in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttcgtgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10452 JY8QFUQ01BHTRG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10453 JY8QFUQ01AXNDN No results 10454 JY8QFUQ01DAWZK productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10455 JY8QFUQ01BZ6M2 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 10456 JY8QFUQ01C8ROP productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1007 96.74 208/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARDGTSSPEPNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ctggattcaGccttcagtaactatgacatacactgggtccgccaggctccaggcaAaggggctggagtgggtggcagttatatggtatgatggaagtaataaatactatgcagagtccgtgaagggccgattcgccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcttgagagtcgaggacacggctgtgtattactgtgcgagagatggaaccagctcgccggagcccaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10457 JY8QFUQ01CUW9U productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDRNYAFDYW in-frame + ctctggattcaccttcagcagctttagtatgaactgggtccgccaggctccagggaagggactggagtggctttcatacattagtaatactggtagtaacaaatactacgcagactctgtgaagggccgattcaccatctccagagacgatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgtgcgagagatcggaactacgctttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10458 JY8QFUQ01BONLS unproductive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKGRGYNDYGLDY## out-of-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggccccgggaaccctgctcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10459 JY8QFUQ01AD0NK No results 10460 JY8QFUQ01A2QEG productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGPGGGWYAEQW in-frame + gtctggattcagtttcagtgactatgccatgcactgggtccgccagactccaggcaaggggctggagtgggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10461 JY8QFUQ01BIS54 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaaggacccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10462 JY8QFUQ01DOC2V unknown (see comment) Homsap IGHV4-61*02 F (see comment) 702 80.65 175/217 nt 80.18 174/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgccctttgtacacaccgcccgtcgctactaccgattggatggtttagtgaggccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10463 JY8QFUQ01A4KC1 unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 820 86.3 189/219 nt Homsap IGHJ5*01 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.17.38.11] CARDQRDYDYIYYYGMD#SG out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtattatgcagacttcgtgaagggccgattcaccatcaccagggacaattcccagaacactctgtctctgcaattgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacgggatggacctctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10464 JY8QFUQ01BI8GQ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 1 10 7 12 10.7.12 [1.17.38.11] CARLTDWWGHFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcggtacttctcattactGggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtgggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10465 JY8QFUQ01B5TP7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - gcctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 10466 JY8QFUQ01AKX3F productive Homsap IGHV4-4*07 F 590 86.54 135/156 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 X 7 15 X.7.15 [X.7.38.11] CARQRGGGDRQWAFENW in-frame - ggactggagtggattgggcgnatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccacccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10467 JY8QFUQ01AYMY9 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10468 JY8QFUQ01BF9OL unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 10469 JY8QFUQ01CT3WE No results 10470 JY8QFUQ01AC0IS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10471 JY8QFUQ01ALRD3 unproductive Homsap IGHV3-48*02 F 971 94.88 204/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CARPAGEGDPFS#YYSGLDVW out-of-frame - ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgaccctttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10472 JY8QFUQ01BHBI8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10473 JY8QFUQ01BPIYL productive Homsap IGHV1-24*01 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10474 JY8QFUQ01DHOH7 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1003 98.55 204/207 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame + aactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 10475 JY8QFUQ01B0FPZ productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10476 JY8QFUQ01ARP0R unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 109 50.24 105/209 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found ttctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10477 JY8QFUQ01DWT8O unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CANEVGYCSSG# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtgggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10478 JY8QFUQ01AMN4Y unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 751 82.87 179/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10479 JY8QFUQ01B8RZ5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10480 JY8QFUQ01B4LFK productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 930 91.03 203/223 nt Homsap IGHJ6*01 F (see comment) 180 76.19 48/63 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggggtcaccttcagtgacgcctggatgacctgggtccgccaggtttccgggaaagggctggagtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatttggaaatgaacagtttgaagagggaggacacggccgtgtattactgtgtgagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggtcaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 10481 JY8QFUQ01CMYZK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10482 JY8QFUQ01AS4RT No results 10483 JY8QFUQ01BZK7M unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F (see comment) 765 83.41 181/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagaagttatggcatgcactgggtccgccgggctccaggcaaggggctggagtgggtggcacttgtgtcatatgatggaagtcataaatattatacagactccgtgacgggccgattcaccatctccagagacaattccaaaaatatgttgtatctacaaatcgacagcctgagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10484 JY8QFUQ01A2GOZ unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.37.11] CARENGSGPPQH#DVW out-of-frame + in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagcccgaggacacggccgtctactactgtgcgagagaaaatggttcgggccccccacagcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10485 JY8QFUQ01AERH9 productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcagg 10486 JY8QFUQ01ASO9V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttcccccgaaccggtgacggtgtgcgtggaactcag 10487 JY8QFUQ01AVBNC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD5-24*01 ORF 3 10 7 15 10.7.15 [1.17.38.11] CARRTGSDGFREGFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtactggttattactgggcctggatccgccagcccccaggaaAagggcctggagtggattggaagtatccataagcttgggaacacctataacaacccgtccctcaagagtcgagccaccatctccgtggacaagtccaagaaccagttctccctgaggctgaggtctgtgaccgccgcagacacgggtgtgtattattgtgcgagacgaacaggcagcgatggcttcagagagggtttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10488 JY8QFUQ01AVHXS No results 10489 JY8QFUQ01DEDXM unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat 10490 JY8QFUQ01DAV7M productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10491 JY8QFUQ01A5O1J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [2.16.38.11] CATSRGSANWYPFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctggattcaatttcagtaattacaccatgaactgggtccgccagcctccaggaagaggctggagtgggtcgcatccattaatgttggcactacttatatatattacggagacgcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10492 JY8QFUQ01BRUOX No results 10493 JY8QFUQ01C9VCP No results 10494 JY8QFUQ01CXTJW productive Homsap IGHV3-48*02 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKDRGGSAYPIFDYW in-frame - gcctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaatagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10495 JY8QFUQ01BJQPU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKIDPNTNWPTDFW in-frame - ctctggattcacctttagcagctttggcatgaactgggtccgccaggctccagggaagggcctggagtgggtctcagcaataggtcgtgctgtcactagcacatattacgcagcctccgtgaagggccggttcaccatctccaaagacaattccaggaacacggtatatctgcaaatgaacagtttgagagccgacgacacggccttatatttctgcgcgaagattgatcccaataccaattggcctactgacttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10496 JY8QFUQ01A4M9B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 883 89.5 196/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [2.17.38.11] CARILTLFAVVTSSGMDVW in-frame - Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) gcctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggccgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10497 JY8QFUQ01CQCGP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10498 JY8QFUQ01AKMHL No results 10499 JY8QFUQ01AWP6D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgcctggtccagggcttcttccccc 10500 JY8QFUQ01AZ1TU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 790 85.92 183/213 nt 85.45 182/213 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CAKTQPFGTTWYGATDAW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) ctctggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgagcagcctaagagccgaggacacggccttatattactgtgcaaagacgcagccgtttggcaccacctggtacggtgctacggatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10501 JY8QFUQ01BEJEJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10502 JY8QFUQ01B8W3M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - gcctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10503 JY8QFUQ01A1UXL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + cggctggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10504 JY8QFUQ01C835G No results 10505 JY8QFUQ01BLOLV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10506 JY8QFUQ01CVAJT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 1 10 7 12 10.7.12 [0.17.38.11] CARLTDWWGHFDHW in-frame - tggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtgggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10507 JY8QFUQ01A39P0 No results 10508 JY8QFUQ01AKOZR No results 10509 JY8QFUQ01AQTUT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 558 72.81 158/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (72,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10510 JY8QFUQ01DHHV8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10511 JY8QFUQ01BKBNG productive Homsap IGHV3-11*01 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVGSMNIEASPPDDW in-frame - gcctcgggttcagcgtcagtaataacttcatgacctgggtccgccaggctccggggaaggggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgaacagcctgagagccgaggacacggccgtctattactgtgcgaaagttggcagcatgaatatcgaggcgagccctcctgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacatggtcatcgcctgcctggtccagggcttcttccccca 10512 JY8QFUQ01B7H46 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctCcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10513 JY8QFUQ01AW0AD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10514 JY8QFUQ01DEK7Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 787 85.19 184/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARRSGRDGGWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 10515 JY8QFUQ01C67L4 No results 10516 JY8QFUQ01BBPXX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10517 JY8QFUQ01CBXMD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.16.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10518 JY8QFUQ01C7A0D productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10519 JY8QFUQ01A7FE0 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10520 JY8QFUQ01BQAON productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPHHNSGYSFDHW in-frame + cgtctgatttcaacgtcggtgactttgacatgcactgggtccgccagactccagacaaggggctggagtgggtggcacttttttggtatgacggaaagaggaaatattatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatggacagcctgagagccgacgacacggctacctacttttgtgcgaggcctcatcataatagtggttattcctttgaccactggggccagggaacccaggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatcgcctggtcaggcttcttcccccga 10521 JY8QFUQ01BSNGL No results 10522 JY8QFUQ01B91QK No results 10523 JY8QFUQ01AQ7NM productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10524 JY8QFUQ01ADN6X No results 10525 JY8QFUQ01DB7WG No results 10526 JY8QFUQ01AIM1I productive Homsap IGHV3-11*04 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame - cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10527 JY8QFUQ01AQP2P unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10528 JY8QFUQ01BOHHB unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 10529 JY8QFUQ01AHCLR productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10530 JY8QFUQ01BTS32 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10531 JY8QFUQ01A1J79 No results 10532 JY8QFUQ01A4ONL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgagagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10533 JY8QFUQ01DBY4U unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 10534 JY8QFUQ01ALX54 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10535 JY8QFUQ01DRRVW productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 973 94.06 206/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDAFEMW in-frame - gcctctggattcacctttgatgattttggcatgagttgggtccgccaagttccagggaaggggctggagtgggtcgctggtatcagttggaatggaggcaaaacaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcattgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10536 JY8QFUQ01ACTFT No results 10537 JY8QFUQ01BQMV0 productive Homsap IGHV4-61*02 F (see comment) 686 79.19 175/221 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARERDRSIGGASELDSW in-frame + Low V-REGION identity (79,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctcttctgtccccataagcagtggtggttactattggaactggatccggcagcccgccgggaaggggctggagtggatcggacgtgttgacagtaatgggttcgtcaggtacaacagttccctcaagagtcgactttctatgtcggtggacatgtccaagagtcaggtctccctgaggttgaggtctgtgatcgccgcggacacggccgtatactattgtgcgcgagaacgcgataggtcgattggcggagcgtcagaacttgactcctggggccagggatctctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 10538 JY8QFUQ01AQ4WG No results 10539 JY8QFUQ01BZ42A No results 10540 JY8QFUQ01AMM1A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctaggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10541 JY8QFUQ01CXALF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10542 JY8QFUQ01DMQOQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 84 51.52 68/132 nt 8 8 X 8.8.X [2.17.9.X] null - No rearrangement found stop codons gcctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 10543 JY8QFUQ01CIOY1 productive (see comment) Homsap IGHV3-48*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 20 8.8.20 [2.17.38.11] CARARRTISGVVFIEHYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaggacccatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcattcattagtagtagtagtggtaccataAttttatgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactttatctgcaaatgaacagcctgagagacgaggatgcggctgtgtattactgtgcgagagcccgtaggacgatttctggagtggtttttattgagcactacggtatggacgtctggggcccagggaccacggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10544 JY8QFUQ01CAESX No results 10545 JY8QFUQ01B61FL productive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaAaagggccgattcaccactcccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10546 JY8QFUQ01DK87J productive Homsap IGHV4-4*07 F 953 93.95 202/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLLTVTTGALDIW in-frame + tttctggtggctccctcagtagttactactggaactggatccggaagcccgccggggagggactggagtggattgggcgtatttactacagtgggagcaccaattacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctaaagctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcttacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10547 JY8QFUQ01CXSE7 No results 10548 JY8QFUQ01BNHO0 No results 10549 JY8QFUQ01DC522 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10550 JY8QFUQ01AMZ3Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10551 JY8QFUQ01DMH5G unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDAFDV# out-of-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaaggacaatggtcaccgtctctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10552 JY8QFUQ01BUB6H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10553 JY8QFUQ01CI79S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10554 JY8QFUQ01BYIDH No results 10555 JY8QFUQ01BL3CK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10556 JY8QFUQ01B00WG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); agcctctacattcGccctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10557 JY8QFUQ01AOTAE unproductive (see comment) Homsap IGHV4-61*02 F 925 90.99 202/222 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [2.17.38.11] CAREK**SV#NWFDPW out-of-frame - stop codons gtctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10558 JY8QFUQ01BS6QJ No results 10559 JY8QFUQ01B2W9U No results 10560 JY8QFUQ01B4VTT productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARMGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagaatgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10561 JY8QFUQ01CCW4G productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame - tctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10562 JY8QFUQ01B6XCF productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 880 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); tctggattcaccgtcagtaccaagGttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10563 JY8QFUQ01A72FV productive Homsap IGHV3-11*01 F 948 93.93 201/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CARDPHRGDGCTYDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcaccttcagtgactaccacatgggctggatccgccaggctccagggaaggggctggagtgcgtttcatacattagcactagtggtcgtgacatatacaacgcagactctgtgaagggccgattcaccatctccagggacaacgcccagaagtcactgtatctgcaaatgaacagcctgagagccgaggacacagccgtgtatttctgtgcgagggatccccatcgtggagatggctgcacttacgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10564 JY8QFUQ01AHL3I productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1080 97.79 221/226 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 9 11 10.9.11 [1.17.38.11] CARLDYTRYFDYW in-frame - ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10565 JY8QFUQ01CYYZE No results 10566 JY8QFUQ01DOU9I productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 10567 JY8QFUQ01CN2IZ unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 436 66.98 144/215 nt 10 9 X 10.9.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (66,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10568 JY8QFUQ01APU75 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtaacggtgtcgtggaact 10569 JY8QFUQ01DRLUL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGIVGDTFFDYW in-frame + cctctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgagatcccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10570 JY8QFUQ01C3ZMO productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10571 JY8QFUQ01B8LLE productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10572 JY8QFUQ01CA1P8 No results 10573 JY8QFUQ01CXMQ6 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10574 JY8QFUQ01BJM6L productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 10575 JY8QFUQ01B0EEH productive (see comment) Homsap IGHV3-48*01 F (see comment) 763 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAagggnctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10576 JY8QFUQ01B9XTE No results 10577 JY8QFUQ01AEKIC No results 10578 JY8QFUQ01CF7J5 No results 10579 JY8QFUQ01BT63X unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQK#WFDPW out-of-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaagctggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagacctctgggggccacagcgcccttgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactcag 10580 JY8QFUQ01BIDN9 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-16*02 F 1 8 8 X 8.8.X [1.17.38.11] CVRRGM*RAD#DAFDIW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgaactgggtccgcctggCctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatgtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10581 JY8QFUQ01CXOHG unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-21*01 F 2 9 7 X 9.7.X [1.17.38.11] CTSREHALVVNSR#DYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'GTC' (3 nucleotides at position 24 to 26 in the user submitted sequence), (do not cause frameshift); tgtctggtgtctccgtcaccagcGTCagtcactggtggacctgggtccgccagcccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgctttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10582 JY8QFUQ01BZG0Q productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10583 JY8QFUQ01BFWQ9 productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgnccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10584 JY8QFUQ01AVMHK productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctctggattcccttTttagaacctattggatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10585 JY8QFUQ01A45ND productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10586 JY8QFUQ01B9JJT productive Homsap IGHV1-2*02 F 817 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame - tggatatactttcaccgaccattatgtttactggatgcgacaggcccctgganaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10587 JY8QFUQ01AOXYI unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CARLPFIVVVTGAFFGTL*LL# out-of-frame + stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggGggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgttttttgggacactttgactattgggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10588 JY8QFUQ01CTGKM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10589 JY8QFUQ01DQJQS productive (see comment) Homsap IGHV3-48*03 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10590 JY8QFUQ01C0BZ0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10591 JY8QFUQ01BMWJ8 productive (see comment) Homsap IGHV4-39*02 F (see comment) 781 83.78 186/222 nt 82.43 183/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 9 7 22 9.7.22 [2.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'TAC' (3 nucleotides at position 30 to 32 in the user submitted sequence), (do not cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'CT' (2 nucleotides at position 32 to 33 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 2 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctgtctccggtgtctcccattagtagtgaTACTttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10592 JY8QFUQ01BI4Q0 No results 10593 JY8QFUQ01AD3OR No results 10594 JY8QFUQ01AGW41 No results 10595 JY8QFUQ01DIOHI productive Homsap IGHV4-4*07 F (see comment) 720 81.57 177/217 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD3-3*02 F 3 10 7 16 10.7.16 [2.17.38.11] CARSGYTSIVGVREFDSW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DIOHI ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggcgggcccccatgactgataaaaattactattggagttggatccggcagcccgccgggaagggactggagtggctcggacgtgtttatggtagcgggagcacaagctccaatccctccgtcaggagtcggatcaccatgtcaatatacacgtctatgaaccaattctccctgaggttgagttctgtgaccgccgcggacacggccgtctattattgtgcgagatcaggttatacttccattgtcggagtgagggagtttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10596 JY8QFUQ01AZ6AK No results 10597 JY8QFUQ01B9VEW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10598 JY8QFUQ01A4DNG unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [1.17.38.11] CARKGLVPSMFFFDF## out-of-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggcccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccttggcaccctcctccaagagcacctctggggggccacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10599 JY8QFUQ01DV8LF productive Homsap IGHV3-74*03 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATGPDYAYAMW in-frame + cctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccca 10600 JY8QFUQ01A7TRV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDLVVTSIGPQGIHGHW in-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 10601 JY8QFUQ01CKBJQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 864 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggccctgccgctggccttcacacagaagaccatcgaccgcttggcgggt 10602 JY8QFUQ01BJO34 unproductive Homsap IGHV3-48*01 F 815 86.24 188/218 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGAGLDV## out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctgggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 10603 JY8QFUQ01BZ3T1 productive (see comment) Homsap IGHV2-5*02 F 1071 93.44 228/244 nt 93.03 227/244 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 3 10 7 13 10.7.13 [9.17.38.11] CAHRRVGTATAFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagtaacagtggagtgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttggacacaCttttttgggatgatgataagcgctacagtccctctctgaaaagcaggctcaccctcaccaaggatacctccaaagaccaggtggtccttgaaatgaccaacatggaccctgtggacacagccacttattactgtgctcacagacgtgtggggactgcgaccgcttttgatttctggggccaggggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10604 JY8QFUQ01AMKYK No results 10605 JY8QFUQ01DTIM6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) gcctcctggattcacCctttggttattatggcatgactggtccgccaagctccggggatgggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10606 JY8QFUQ01CKI20 No results 10607 JY8QFUQ01B8D22 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 890 90.7 195/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [1.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01B8D22 ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgacgcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10608 JY8QFUQ01CEH7I productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.24 198/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKGRGYNDYGLDYW in-frame + ctctggattcaccttcagtgactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtgacagttattttatatgatggaagtagaaaatactatgcagactccgtgaagggccgattcgccatctccagagacgtttcgaggaacacgttgtatctgcagatgaatagcctgagacctgaggacacggctgtatactactgcgcgaaaggacgtggatataatgactacggcctcgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10609 JY8QFUQ01CVO57 productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttcccc 10610 JY8QFUQ01DHV9M unknown (see comment) Homsap IGHV3-48*01 F 820 86.3 189/219 nt 85.84 188/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaTggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctgggactctgggggcccaagggaccacggtcgccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10611 JY8QFUQ01B45Q5 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10612 JY8QFUQ01BP7R4 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1076 97.36 221/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgagaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10613 JY8QFUQ01ADMJX productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagccCcccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10614 JY8QFUQ01BKW6J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10615 JY8QFUQ01BE6BR productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10616 JY8QFUQ01BU14D productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*07 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gcctctggattcaTgcttcagCaagccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10617 JY8QFUQ01BMDI0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10618 JY8QFUQ01AWFVX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10619 JY8QFUQ01DDMV5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagccctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10620 JY8QFUQ01BAGLD productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARQRGPGIGTVGLDYLG in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatatgtcttcaatgactactatatacactgggtgcgacaggcccctggacaaggacttgagtggatggggtggatcaaccccaccagtggtgtcacaaactatgcgcagaagtttcagggcaggatcgtcatgaccagggacacgtccatcgatacagcctacttggaggtgaccagggtgaagtttgacgacacggccgtctattactgtgcgcgacagagaggtcccggtatagggacagttggcttggactatttgggggccaggggtaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10621 JY8QFUQ01DL7V8 No results 10622 JY8QFUQ01B0YNB No results 10623 JY8QFUQ01C1YGN No results 10624 JY8QFUQ01BKECC No results 10625 JY8QFUQ01DNPGO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10626 JY8QFUQ01B4MWK productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 780 84.09 185/220 nt 83.64 184/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [2.17.38.11] CARDGSAHSPISHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); agcctctggaAttctccttaagttctcatacaatgaattgggtccgccaggctccagggaaggggccggagtgggtctcaactattggcaccagagggagatccatatactacgcggactcagtgaagggccgattcatcacctcgagagacaacgccgggcacgcactatatctggagatgcacaacctgagagccgaggacacggctatgtattactgtgcgagagatggtagtgctcactcgccaatctcacattactattacggcatggacgtctggggccaagggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10627 JY8QFUQ01DQF6F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1013 95.87 209/218 nt Homsap IGHJ1*01 F, or Homsap IGHJ4*02 F (see comment) 145 78.72 37/47 nt Homsap IGHD4-17*01 F 2 8 8 6 8.8.6 [1.17.38.11] CANYGQWL in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctaattacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10628 JY8QFUQ01BHQWH No results 10629 JY8QFUQ01CJWBE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame - ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10630 JY8QFUQ01DPZU3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - ctctaaagttcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10631 JY8QFUQ01C2U95 No results 10632 JY8QFUQ01B5Z4M No results 10633 JY8QFUQ01CZU05 unknown (see comment) Homsap IGHV2-5*03 F 172 54.45 104/191 nt 10 7 X 10.7.X [9.17.25.X] null + No rearrangement found accctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 10634 JY8QFUQ01CJFIA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10635 JY8QFUQ01BAAGC unknown (see comment) Homsap IGHV3-74*03 F 117 54.07 73/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10636 JY8QFUQ01AWH4C productive (see comment) Homsap IGHV4-4*07 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLPTVTTGALDIW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggtggctccttcagtaattaccactggagctggatccggaagcccgccgggaaggaactggagtggattgggcgtatccatcacagtgGggctcaccaactccaacccctccctcaagaatcgagtcgtcgtgtcagtggatacgtccaagaatcagttgtccctggagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcctacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggactgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10637 JY8QFUQ01A2KE1 No results 10638 JY8QFUQ01A5679 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ6*04 F (see comment) 90 60.32 38/63 nt Homsap IGHD2-21*02 F 2 8 8 20 8.8.20 [2.17.38.11] CAKDRTLHTPAQMFYYGMDAWG in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggatttaccttcagttcttatagtgtcaactgggtccgccaggctccagggaagggcctggagtGgggtctcatatattgataatagtggttctaccatatattatgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggccgtttattactgtgcgaaagatcggacactacacacacccgctcagatgttttattatggtatggacgcctgggggcccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10639 JY8QFUQ01B7EF5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.16.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaagggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactc 10640 JY8QFUQ01CQBXU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 90.14 192/213 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10641 JY8QFUQ01CUS6E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10642 JY8QFUQ01BT3LW No results 10643 JY8QFUQ01CYBZL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10644 JY8QFUQ01CLMUE unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 557 73.02 157/215 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [0.17.38.6] PV## out-of-frame - Low V-REGION identity (73,02% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10645 JY8QFUQ01CC7RP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacaGttttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10646 JY8QFUQ01AEXAB unproductive (see comment) Homsap IGHV3-11*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSX*F*VL in-frame + stop codons cctctggcttcaccttcagtgactactacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgnactgattttgagtactgggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggccttcttccc 10647 JY8QFUQ01A1J69 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10648 JY8QFUQ01CXE58 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); ctctggggactccattagtggttactattggacgtggatccggcagAcccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10649 JY8QFUQ01ALF1M unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcag 10650 JY8QFUQ01BCH6P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10651 JY8QFUQ01CUGGP productive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10652 JY8QFUQ01C8Z01 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10653 JY8QFUQ01B6DL7 productive Homsap IGHV3-66*02 F 894 91.12 195/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaagaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10654 JY8QFUQ01CZO4B productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 880 88.74 197/222 nt 87.39 194/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 1 8 10 9 8.10.9 [1.16.38.11] CTTWFDDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'A' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggactcactttcagcaacgcctggatgagatGgggcccgccaggctccagggagggggctgagtgggttggccgcattaaaagtaaagctgatggtgggacaacagacAtttgatgcagccgtgaaaggcagattcaccctctcaagagacgattcgaaaaatacgatatatctgcaaatgaatcgcctgaagactgaggacacaggtgtttattactgtaccacatggttcgacgactttgactactggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10655 JY8QFUQ01B1DNN unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null + No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10656 JY8QFUQ01DK6WS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGAAVALTPG in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtgcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10657 JY8QFUQ01C4YGB productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 912 90.13 201/223 nt 89.69 200/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 15 8.10.15 [1.17.37.11] CTTDRRGLSIPPQFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggccgtataaaaaacaaagctatgggtgagacaacagacttcgctgcacccgtgagaggcagattcagtatctcaagagatgattcaaaaatacactgtatctgcacatgagtggcctgaaaaccgaggacacagccgtctattattgtaccacagatcggcggggtttgtctataccacctcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10658 JY8QFUQ01CIOEY No results 10659 JY8QFUQ01AZEAD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10660 JY8QFUQ01A92S8 productive (see comment) Homsap IGHV3-30*10 F (see comment) 761 83.49 182/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); cctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcaCgcagtctcacatgatggtgttagcgagatgtatacagaCccccgtgaagggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 10661 JY8QFUQ01C4QZS productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10662 JY8QFUQ01C8FDH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAKAVPTRVRLDHW in-frame - ctctggattcgactttaacaactttgccatgacctgggtccgccaggctccagggaagggtctggagtgggtctcaggtatcagtggtggcggttttaatacatactacgcagactccgtgaagggccggttcaccgtttctcgagacaagtccaacaacacgttgtttctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagccgttcccaccagagtcaggcttgaccattggggccacggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10663 JY8QFUQ01B8FQE No results 10664 JY8QFUQ01BDMOG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.16.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagatactggGatgcactgggtccgccaggctccagggaaggggctggagtggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10665 JY8QFUQ01A3PVQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 838 87.21 191/219 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - gctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10666 JY8QFUQ01CNN4B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10667 JY8QFUQ01ADMPT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10668 JY8QFUQ01CMBYX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 10669 JY8QFUQ01AGHV3 productive (see comment) Homsap IGHV4-61*02 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 114 in the user submitted sequence), (cause frameshift) ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10670 JY8QFUQ01CNKLI No results 10671 JY8QFUQ01BXLNA productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca 10672 JY8QFUQ01CNHY7 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F (see comment) 694 79.91 175/219 nt 79.45 174/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-1*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRSPNHNWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 184 to 184 in the user submitted sequence), (cause frameshift); ggctctggattcaaattcaataattatgcaatgcactgggtccgccagtctccaagagcggggctgcaatgggtggcggctatatcgactgacggcaataaagaatatcatgcagactccgtgaagggccggctcaccctctccagagacaattcgaggagtacgctgtctctgcaattgcgcAaacctgacagctgacgactcggctctgtattattgtgtcagatctcccaaccacaattggttcgacccctggggccagggagccctggtcactgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10673 JY8QFUQ01C1R7S productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 7 8 11 7.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) cctctggatttactttaacaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtctcagGgtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10674 JY8QFUQ01A7IGG productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10675 JY8QFUQ01BYVL8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 493 92.92 105/113 nt 92.04 104/113 nt 8 8 X 8.8.X [1.16.4.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagac 10676 JY8QFUQ01DNC02 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 10677 JY8QFUQ01AR8UJ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.37.11] CTTGGGTNYYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10678 JY8QFUQ01BLALJ productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 869 86.78 197/227 nt 85.9 195/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 10 12 8.10.12 [2.17.38.11] CSYFRHEPYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); tagacgctggattcgcctctggtgattatgctatgagGttggttccgccaggctccgggcaaAGggggctggagtgggtggggttcatcagaagcagagcttacactgggacaccagaatacgccgcgtctgtgaaaggcagattcaccatctccagagatgcttccaaaagtattggctatctgcaaatgaacaatctgaggatcgaggacacagccgtctattattgctcttattttcggcatgagccatatcactttgactattggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10679 JY8QFUQ01B9V5M productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame + ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 10680 JY8QFUQ01DDV5C unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 768 82.96 185/223 nt 81.61 182/223 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 1 8 10 X 8.10.X [1.17.38.11] CSTGGPNGYHSTYPW# out-of-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); ctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccGggggaaggggcttgagGtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaaGtacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctgggggcccgggggacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10681 JY8QFUQ01AA9FJ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10682 JY8QFUQ01BMJLY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [2.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10683 JY8QFUQ01AYJ8O No results 10684 JY8QFUQ01AF6U3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.37.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 100 of V-REGION: 2 nucleotides (from position 207 in the user submitted sequence), (cause frameshift) agcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10685 JY8QFUQ01C4E75 productive Homsap IGHV4-61*07 F (see comment) 766 83.56 183/219 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) gtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacccctcctcccaagagcacctctgggggcacagcggcccctgggctgcctggtccaagggactacttcccccgaaccggtgacggtgtcgtggaact 10686 JY8QFUQ01BWFM1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) cctccgggattcaccttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10687 JY8QFUQ01A78NA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ2*01 F 242 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFXLW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcnatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10688 JY8QFUQ01CTCXB productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame - tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggataggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10689 JY8QFUQ01B9BPY productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1080 97.79 221/226 nt 97.35 220/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10690 JY8QFUQ01DDCCT productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 967 92.44 208/225 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10691 JY8QFUQ01CE3EU No results 10692 JY8QFUQ01BB4PW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10693 JY8QFUQ01BW6L0 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcacccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10694 JY8QFUQ01DRJLJ No results 10695 JY8QFUQ01AKYM1 No results 10696 JY8QFUQ01BOPT4 productive (see comment) Homsap IGHV3-66*02 F 899 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) agcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcgactgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10697 JY8QFUQ01DUYT0 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttacccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10698 JY8QFUQ01AB8R5 productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10699 JY8QFUQ01ASFP7 No results 10700 JY8QFUQ01BAD27 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10701 JY8QFUQ01A4PFT No results 10702 JY8QFUQ01B2TU9 No results 10703 JY8QFUQ01CB3JH productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARPARPSAVGPFDFW in-frame - tctctggtgactccatcagcggtagcaattggtggagttggatccgccagcccccagggaaggggctggagtggattggggaaatctctcatagtgggaacactaactacaacccgtccctcaagagtcgggtcaccatatcagtcgacaagtccaagagccagttctccctgaacctgagcgctgtcaccgccgcggacacggccgtatattactgtgcgagacctgctcgcccatcggccgtgggaccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10704 JY8QFUQ01AZPLL unknown (see comment) Homsap IGHV4-4*08 F, or Homsap IGHV4-61*05 F 173 56.69 89/157 nt 8 7 X 8.7.X [1.17.18.X] null + No rearrangement found stop codons tctctggtggctcgctcacgggtttcaagtggggctggatccggcagcccccaggggagggactgcaatggattggacatatctcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 10705 JY8QFUQ01CKTX3 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcgtgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10706 JY8QFUQ01CKS0C productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10707 JY8QFUQ01BRNG5 productive (see comment) Homsap IGHV3-13*01 F 970 95.31 203/213 nt 94.37 201/213 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 7 7 13 7.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 190 to 190 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcacgttcagtaatacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccTggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10708 JY8QFUQ01ACENJ productive Homsap IGHV3-21*04 F 985 95.37 206/216 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + tctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10709 JY8QFUQ01DBQ14 No results 10710 JY8QFUQ01ACK8R productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10711 JY8QFUQ01DV8NC productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARGVGQQLPPLDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); gtctctcgtgcctccatGcaatatttcctactggagctggatccggcagcccccagggaggggactggagtggattggatatatctatgatagtgggagtaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10712 JY8QFUQ01DKWN3 No results 10713 JY8QFUQ01BDPXU productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctaatggctccatcagcggaagtgtttactactgggcctgGgatccgccagcccccagagaagggtctggagtacattgggaAgcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttctccc 10714 JY8QFUQ01BANH8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVMREHYYGAGNYPWGGMEVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccatttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10715 JY8QFUQ01B2H4W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 10716 JY8QFUQ01ALGEH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame - ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10717 JY8QFUQ01DE2T0 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-23*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CAGEEMRTRDGGGYGTDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); ctctggtgGgctccatgactctttattattggagttggatccggcagcccgcagggaaggggctggagtgggttgggtacatcgatcacgctgggagcgccaagtataacgcctcccttcagagtcgagtcaccatctcagtcgacgcgcccaagaatcagttctctctgaagttgaactctgtgactgctgcggacacggccgtttattactgtgcgggagaagagatgcgaacgcgggacgggggtggctacggaacggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10718 JY8QFUQ01BR9IG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [2.16.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtaccaagGttcatgagctgggtccgccaggctccagggaagGgggctggagtgggtctcagtaattatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10719 JY8QFUQ01AM9UU No results 10720 JY8QFUQ01CEUTU unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10721 JY8QFUQ01AMSO8 unknown (see comment) Homsap IGHV3-21*04 F (see comment) 667 78.54 172/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (78,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactgggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10722 JY8QFUQ01BNGHM productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTcctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 10723 JY8QFUQ01AIWOI productive (see comment) Homsap IGHV3-48*03 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 10724 JY8QFUQ01DRCAF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 927 91.74 200/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) gcctccggattcacctttagtagtactggatgcactgggtccgccaagctccaggGGgagggactgggtntgggtctcacggaCtaaatgaagatgggagtatcacGaaactacgAcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10725 JY8QFUQ01BZF9G unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10726 JY8QFUQ01CRF3X No results 10727 JY8QFUQ01BOALS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10728 JY8QFUQ01CFMY9 productive (see comment) Homsap IGHV4-4*07 F 786 85.51 183/214 nt 84.58 181/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 6 15 8.6.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AGGC' (4 nucleotides at position 76 to 79 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgAGGCgtcatctctgttcttgaaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10729 JY8QFUQ01BBYJ2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10730 JY8QFUQ01AYJEJ productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10731 JY8QFUQ01BEYE8 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 103 52.99 71/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacctttagtgactattggatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10732 JY8QFUQ01CIT4F productive Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 10733 JY8QFUQ01CVI49 productive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10734 JY8QFUQ01B9RQR No results 10735 JY8QFUQ01DAZD6 No results 10736 JY8QFUQ01BVRVR productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 963 92.04 208/226 nt 91.59 207/226 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 9 8.7.9 [5.17.38.11] CARGGPHFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gccgtctgcagcctctggattcCattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10737 JY8QFUQ01A5SB0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10738 JY8QFUQ01BRQ8F productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10739 JY8QFUQ01A95F9 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggcagccctggtcacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca 10740 JY8QFUQ01AL3XX productive Homsap IGHV3-9*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10741 JY8QFUQ01B9L1U productive (see comment) Homsap IGHV2-5*02 F 1134 96.31 235/244 nt 95.49 233/244 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcattttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaagGgacatctccaaAaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10742 JY8QFUQ01BZY5S productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 967 92.44 208/225 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 7 14 8.7.14 [5.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10743 JY8QFUQ01AJO4L unproductive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 342 61.75 134/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (61,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactcttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10744 JY8QFUQ01BD0HS No results 10745 JY8QFUQ01CFOEY No results 10746 JY8QFUQ01AN3J7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame - cctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10747 JY8QFUQ01AFIHV No results 10748 JY8QFUQ01C8MU7 No results 10749 JY8QFUQ01ASHDH No results 10750 JY8QFUQ01CUDH9 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10751 JY8QFUQ01B6YTM productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 921 92.52 198/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - ctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatcccctaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10752 JY8QFUQ01A35PD No results 10753 JY8QFUQ01COVYR No results 10754 JY8QFUQ01DJ040 unproductive (see comment) Homsap IGHV3-72*01 F 853 87.39 194/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 10 X 8.10.X [1.17.38.11] CAVAAPPL#DGW out-of-frame + stop codons tctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggcctggatgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccgttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagccaccccccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10755 JY8QFUQ01BBP33 No results 10756 JY8QFUQ01BIJZ5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - tctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10757 JY8QFUQ01CR3NS No results 10758 JY8QFUQ01ASM1Z productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcCccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10759 JY8QFUQ01B6OVD No results 10760 JY8QFUQ01CKO1P productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 809 84.82 190/224 nt 83.93 188/224 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-16*01 F 2 8 10 13 8.10.13 [2.16.38.11] CSTGGPNGYESTYPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) gcctctggattGcaccttcaatatcaagtggatgagttgggtccgccaggctccgggaaggggctggagtgggttggccgcatcaagagcacctctgatggtgggacaacagactccattgcacacgtcaaagacagattcatcatctcaagagatgattcaagaaatacactgtacttacaaatgaacaacctgagagtcgaggatacaggcgtctattattgttccacaggagggccaaatggttatgagtctacctatccctggggcccgggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10761 JY8QFUQ01AH452 productive Homsap IGHV3-11*01 F 944 93.49 201/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [0.17.38.11] CARDGDDYRSYYYGMDVW in-frame - ctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10762 JY8QFUQ01BIAPA No results 10763 JY8QFUQ01B7GKQ productive (see comment) Homsap IGHV4-61*02 F (see comment) 754 82.43 183/222 nt 81.98 182/222 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 16 10.7.16 [2.17.38.11] CARERFRSTGGARDFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gtctctggtgAgccccatcagcagtggtgatcacttctggagctggatccggcagcccgccgggaagggactggagtggattggacatgttcactatggtggggtcaccaattacaatccttccctccagggtcgggtcatggtgtctatggacacgtccaagagccagttcttcctgacgatgacctccgtgaccgccgcagacacggccacatattactgtgcgagagagcgtttcaggtcgacgggcggagcgagagattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10764 JY8QFUQ01CD8YB productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10765 JY8QFUQ01AO9ZD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10766 JY8QFUQ01BZSD2 productive (see comment) Homsap IGHV3-11*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaaaaaGctcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10767 JY8QFUQ01BDE5D productive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-11*01 ORF 3 10 7 9 10.7.9 [1.17.38.11] CTKLLNHFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcaatggaggcagttcctactggagctgggtccggcagcccgccgggaggggactggagtggattgggcgtatctatctcagtgggagcaccaactacaatccctccctcaatgatcgagccaccatctcaatcgacccgtccaagaaccagttctccctgaaactgaggtttgtgaccgccgcagacacggccgtatactattgtactaaactacttaaccacttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag 10768 JY8QFUQ01CO019 productive Homsap IGHV3-11*01 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CTRDDRSVRGVTSDYW in-frame + tctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatttttgtacgagagatgatcgctcggttcggggagtcacctcagactactggggccagggaaccctggtcaccgtctcctccgcctcctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcagg 10769 JY8QFUQ01DAK9T unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CASSV*GGQLWPGEL# out-of-frame + stop codons tctctggtggctccatcagtaattacttctggagctggatccggcagcccccagggaagggtctggagtggattgcgaatatctattacaatgggaacaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtctaagaaccagttctccctgaaggtgaggtctgtgaccgctgcggacacggccgtgtattattgtgcgagctcagtttaggggggccagctatggcctggggaactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttcccccga 10770 JY8QFUQ01C6I13 productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 10771 JY8QFUQ01BR33H productive (see comment) Homsap IGHV3-11*01 F (see comment) 747 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 77 of V-REGION: 'N' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); ctctggattcagcttaagtgactactacatgacctgggtccgccaggccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaNccgtctccagggacaacgtccaaaactcacttgttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10772 JY8QFUQ01B161I unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVRGYYGGQYFDS## out-of-frame + ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 10773 JY8QFUQ01A0VAL No results 10774 JY8QFUQ01BR81F unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGGVSGAFRWG#FDYW out-of-frame + stop codons ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggttttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10775 JY8QFUQ01CKC0K unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 541 71.69 157/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (71,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10776 JY8QFUQ01B8DCT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10777 JY8QFUQ01BN3GL No results 10778 JY8QFUQ01BNQSK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKNMAMGEALFDFW in-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgaaaaacatggctatgggagaggcgttgtttgacttctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10779 JY8QFUQ01B8I5W productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10780 JY8QFUQ01A9569 productive Homsap IGHV3-43*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLNYFDHW in-frame + cctcagggttcaactttgatgaatataccatgcactgggtccgtcaagctccggggaagggtctggagtgggtctctcttattagttgggatggtagcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaagattccctgtatctgcaaatgagcagtctgagagctgaggacgccgccttctattattgtgcaaaggataggattgggtccttgaattactttgaccattggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 10781 JY8QFUQ01B1TMD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10782 JY8QFUQ01BVM4A No results 10783 JY8QFUQ01BSUM5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 10784 JY8QFUQ01A7I0L productive Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaagaggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccccaanatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 10785 JY8QFUQ01B1O5A productive Homsap IGHV3-7*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10786 JY8QFUQ01AXTVE unproductive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 89.14 197/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGG**WTLE*LL# out-of-frame + stop codons in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 216 to 216 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatTttttgtgcgagacaagggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10787 JY8QFUQ01DIGTH unproductive Homsap IGHV3-9*01 F 971 94.88 204/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKILGYTCGP#DYW out-of-frame + ctggattcacgtttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaagatattggggtacacatgtggaccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10788 JY8QFUQ01AUOZJ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F (see comment) 133 74.0 37/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaacggtcaccggtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 10789 JY8QFUQ01AZTV5 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARHNYGNEKYIMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'GA' (2 nucleotides at position 27 to 28 in the user submitted sequence), (cause frameshift); ttggatacaactttgccacctattggGAtcgggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatggtctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10790 JY8QFUQ01BOSCN productive (see comment) Homsap IGHV4-4*07 F (see comment) 679 79.63 172/216 nt 79.17 171/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARESTNSIGDPRHLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'CAANACGAC' (9 nucleotides at position 19 to 27 in the user submitted sequence), (do not cause frameshift); gtctctggtggccccatcCAANACGACatggacttctattggacgtggatccggcagtccgccgggaggggactggagtggctcggacatgtctatatgaatggcattagtgaccacaatccagtcttcactagtcgtctcaccatgtccattgacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggactcggccctatattactgtgcgagagaaagtactaattcgattggcgacccgagacaccttgactcttggggccagggaaggttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10791 JY8QFUQ01B53GB productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10792 JY8QFUQ01BZPA4 productive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggcttcaccttcagtgactactacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10793 JY8QFUQ01AT7VB productive Homsap IGHV3-15*07 F 993 94.17 210/223 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 3 8 10 22 8.10.22 [1.17.38.11] CTTAGITMVRGIIINGDYYGMDVW in-frame + ctctggattcactttcagtaacgcctggatgaactgggtccgccaggctccaggtaaggggctggagtgggtcggccgtattaaaagcaaaggtgatggtgggacaacggactacgctgcacccgtgaaaggcagattcagtatctcaagagatgattcagaaaacaagttgtatctgcaaatgaacagcctgaaaaccgaggacacaggcatatattactgtaccacagccggtattactatggttcggggaattattataaacggtgactattatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagtgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg 10794 JY8QFUQ01BN655 No results 10795 JY8QFUQ01A86H8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 85 57.75 41/71 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccca 10796 JY8QFUQ01DLPCH productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARGGATWELLLGNLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'GC' (2 nucleotides at position 110 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcaGCcaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagagggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10797 JY8QFUQ01DTEZT unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGGQRLGL#DYW out-of-frame + in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacaGcggctntataTtttctgtgcggggggccagaggctgggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10798 JY8QFUQ01AA9UM productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + tctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10799 JY8QFUQ01B4JYA productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10800 JY8QFUQ01BI2PW productive (see comment) Homsap IGHV3-7*01 F 997 94.59 210/222 nt 93.69 208/222 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [3.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); gcgacctctggattcaccttTtagtaaccattggatgaactGgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10801 JY8QFUQ01CFLMK productive Homsap IGHV3-11*01 F 860 88.53 193/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + cctctggattcaccttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggaatggatctcatatatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacaccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggagattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10802 JY8QFUQ01CGL8I No results 10803 JY8QFUQ01C0VWG unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10804 JY8QFUQ01BXB22 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 866 90.09 191/212 nt 89.62 190/212 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.16.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccaggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10805 JY8QFUQ01DPHF7 productive (see comment) Homsap IGHV4-61*02 F (see comment) 628 76.13 169/222 nt 75.68 168/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 10 7 16 10.7.16 [2.17.38.11] CARERDKSGGGAGDFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 34 of V-REGION: 'CGAAGGATTT' (10 nucleotides at position 24 to 33 in the user submitted sequence), (cause frameshift); gtctccagtggcattattaatagCGAAGGATTTtggtcgtttctactggaactgggtccggcagatcgacgggcaggggctggagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctgaagttacagtctgtgaccgccgcagacacggccgtatatttttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10806 JY8QFUQ01BVRED productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10807 JY8QFUQ01B5QTF No results 10808 JY8QFUQ01AKBT4 No results 10809 JY8QFUQ01DRPI3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 774 84.33 183/217 nt 82.95 180/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [2.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) acgtctgggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10810 JY8QFUQ01DWFTQ unproductive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 912 92.06 197/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CAREQFYYNSGTYHHYHMDV## out-of-frame + tggagacacattcaccagctatgctatcagctgggtgcgacaggcccctggacaagggcttcagtggatgggagggatcatccccagatatggtatatcacactacgcacagaagttccagggcagagtcacgattaccgcggacagatccacgggcacagcctacatggagctgaccagcctgacgtctgaggacacggccctgtattactgtgcgagagaacaattttactataatagtgggacttatcaccattaccatatggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10811 JY8QFUQ01CYHYD No results 10812 JY8QFUQ01B6Z1N productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.37.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 201 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtAGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacgctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10813 JY8QFUQ01CRPFQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10814 JY8QFUQ01CIB0W unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1125 100.0 226/226 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CAREEWELPLDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctccggggacagtgtctctagcaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtgtattactgtgcaagagaagagtgggagctaccgcttgatgcttttgatatctggggccaagggtacaatggtcaccgtctcttcagggagtgcatccgccccaatccc 10815 JY8QFUQ01A4VXL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctctggattctccgtcagtaattactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10816 JY8QFUQ01A0VCZ No results 10817 JY8QFUQ01DS915 unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F (see comment) 634 76.85 166/216 nt 76.39 165/216 nt 8 7 X 8.7.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (76,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gtctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 10818 JY8QFUQ01BZU4R productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*02 F 109 70.21 33/47 nt Homsap IGHD5-12*01 F 3 8 8 6 8.8.6 [1.17.38.11] CVSIGHGV in-frame + ctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtcgcacacattgacactgatgggagtatcgcagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatactttgtatctgcaaatggacagtctgagagccgacgacacggctatatattactgtgtaagcattggacacggagtgggcccgggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacatggtcgtcgcatgcctggtccagggcttcttccccca 10819 JY8QFUQ01DK0WV No results 10820 JY8QFUQ01AX80T productive (see comment) Homsap IGHV3-48*02 F (see comment) 716 80.73 176/218 nt 80.28 175/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggGAaggggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggatggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 10821 JY8QFUQ01C9SOA unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 651 83.42 156/187 nt Homsap IGHJ1*01 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-11*01 ORF 2 X 8 X X.8.X [X.16.38.11] TPEIPG## out-of-frame - stop codons Low V-REGION identity (83,42% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gagtggggtccgccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgtttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10822 JY8QFUQ01BYSP9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10823 JY8QFUQ01DXDWF No results 10824 JY8QFUQ01A4U6K productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10825 JY8QFUQ01A0OJJ productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 10826 JY8QFUQ01C15UA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.16.38.11] CARFGPLTRPDY## out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 10827 JY8QFUQ01B4DKB unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 814 97.65 166/170 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found ctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc 10828 JY8QFUQ01DKNML productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10829 JY8QFUQ01C6HZC No results 10830 JY8QFUQ01CJ8L9 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgagaacgtggtcatcgcctgcctggtccagggcttcttccccc 10831 JY8QFUQ01AOWLX productive (see comment) Homsap IGHV1-3*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.37.11] CARWNNDLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 152 in the user submitted sequence), (cause frameshift) ctggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatcgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10832 JY8QFUQ01DFL6S productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cgtctggattcaccgtcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgGaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10833 JY8QFUQ01CRL0P productive Homsap IGHV3-7*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10834 JY8QFUQ01ABJSU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10835 JY8QFUQ01CH45V No results 10836 JY8QFUQ01B1QAD No results 10837 JY8QFUQ01B0JM4 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10838 JY8QFUQ01A3TN3 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 699 80.0 176/220 nt Homsap IGHJ4*02 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CARERGTTVGGASE#FDSW out-of-frame + stop codons Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggtggccccgtcattattgatggttattactggacgtggatccgtcagcccgccgggaagggactggagtgggtcggacgtgtcaccagtcgtggggagaccaattacagttcctccctcaagagtcgaattttcatgtcagtagacacgtctaagaatcaattctccctgaggtttaattctgtgaccgccgcagacacggccctatattactgtgcgagagaacgcggtactacagttggcggggcgagcgaattttgactcctggggccagggagtgcaggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 10839 JY8QFUQ01CNGUC No results 10840 JY8QFUQ01DOO1G No results 10841 JY8QFUQ01BOIQ7 productive (see comment) Homsap IGHV3-11*01 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.16.38.11] CVTRRLGSTYTTFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcactgactactacatgaattggatccgccaggctccggggaagggctggaatgggtttcatacattggaaccgatgatcaaaccagattttacgcagactctgtgaagggccgattcaccatctccacggacaacgcccagaattctgtgtttttgcaaatgaccagcctgcgagccgaggacacggccatgtattactgtgtgacacgtcgactgggaagtacctatacgacttttgatttttggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10842 JY8QFUQ01A5VM1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10843 JY8QFUQ01A4JG3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcaccagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 10844 JY8QFUQ01AV3VG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 7 8 15 7.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ttctggattcagtcctaccgattttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaa 10845 JY8QFUQ01BGINF unproductive Homsap IGHV3-7*03 F (see comment) 374 82.73 91/110 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD4-11*01 ORF 3 X X X X.X.X [X.X.36.11] CARDRYSSDSSYYMPNWLD#PW out-of-frame + Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttgggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgaccccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10846 JY8QFUQ01CZ3ME No results 10847 JY8QFUQ01BAKET productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 981 94.93 206/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggactggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggaagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 10848 JY8QFUQ01BQQBC productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10849 JY8QFUQ01AOTBL unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKS*LW#YYFDQW out-of-frame + stop codons ctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaatcatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10850 JY8QFUQ01AON9Y unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 746 83.26 179/215 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDKVISAGRDV## out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AON9Y ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggcccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10851 JY8QFUQ01AUW74 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 789 86.26 182/211 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 8 9 7.8.9 [X.17.38.11] CTGLTYPDDYW in-frame + atttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggcctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10852 JY8QFUQ01AMEYY No results 10853 JY8QFUQ01A8A4C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.37.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10854 JY8QFUQ01B0WNX unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 133 63.64 49/77 nt 8 X X 8.X.X [1.16.X.X] null + No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 10855 JY8QFUQ01DXF20 unproductive Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGPVSG#YTDYW out-of-frame + in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctgtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10856 JY8QFUQ01AF35K productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); gttctggatacaactttcccagatattggatcgcctCgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10857 JY8QFUQ01C1Z2H productive (see comment) Homsap IGHV3-7*02 F 928 91.78 201/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'CC' (2 nucleotides at position 13 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcCCatttttagaacctCattggatgagttgggtccgccaggctccagggaAaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10858 JY8QFUQ01AU76E productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 10859 JY8QFUQ01CF6EU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10860 JY8QFUQ01AF52M unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARADDYGDYP#EFW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactacccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10861 JY8QFUQ01AOATE unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 267 62.42 103/165 nt 8 10 X 8.10.X [1.17.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01AOATE ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10862 JY8QFUQ01BUHUI No results 10863 JY8QFUQ01CWJTG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 427 88.79 95/107 nt 85.98 92/107 nt 7 8 X 7.8.X [2.16.1.X] null - No rearrangement found in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) cctctgggattcaccttcagtagctatagatgaactggtccgcccagctccagggaaggggctggagtggtctcatacattagtaggagtagtactgacatatacta 10864 JY8QFUQ01CECME No results 10865 JY8QFUQ01CNEDF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10866 JY8QFUQ01DDQ8A productive (see comment) Homsap IGHV3-7*02 F 960 93.18 205/220 nt 92.27 203/220 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'CT' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); agcctctacattcacgtttagtcggtattggatgagctgggtAccgccaggctccaggggaagggcCTgggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10867 JY8QFUQ01DSCVL No results 10868 JY8QFUQ01CZJGN No results 10869 JY8QFUQ01BKWM8 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10870 JY8QFUQ01BKF2J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 712 80.82 177/219 nt 80.37 176/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [2.17.38.11] CARYRVGDSLYYGLDGW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 91 to 93 in the user submitted sequence), (do not cause frameshift); gcctctggattcattttagaaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10871 JY8QFUQ01AKFEZ unknown (see comment) Homsap IGHV4-61*02 F 910 90.87 199/219 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaagtagtgatccgtcccaattggttcgacccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10872 JY8QFUQ01BHLSH productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [2.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10873 JY8QFUQ01A1X35 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 911 90.5 200/221 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDRLGSCSGASCPVYYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcaacagtggtgattcctcctggacctggatccgccagtacccagggaagggcctggagtggattgggtacatctctggcagtggggactcctactccaacccggccctcaagagtcgagttaccatatcagtggacacgtctaagagccagttcttcctggaactgagttctgtgactgccgcggacacggccgtctattactgtgcgagagatcggctgggatcttgtagtggggctagctgccccgtctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg 10874 JY8QFUQ01DE2O2 unproductive (see comment) Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-15*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREKG**SV#NWFDPW out-of-frame + stop codons tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaaggctagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10875 JY8QFUQ01A4MMY unproductive (see comment) Homsap IGHV3-48*04 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGILLLLWSGRL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatgggatacttctattactctggtctggacgtctgggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10876 JY8QFUQ01CB7M9 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10877 JY8QFUQ01COI40 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGSGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggtccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10878 JY8QFUQ01AFKMW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDVQFLEWSLPPLDYW in-frame + cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgcgagccgaggacacggctgtgtattactgtgcgagagatgtccaatttttggagtggtcattaccacccttagactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10879 JY8QFUQ01AL8T2 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10880 JY8QFUQ01A9M1O productive Homsap IGHV4-4*07 F (see comment) 557 73.49 158/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARVRDAYTAGHFDSW in-frame + Low V-REGION identity (73,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactctgtcactatgtcttattgggcctggatacgtcagcccgccgggggaggcctggagttaattggacgaacttctgccagtccaaaagttacctacaatccctccctcaggagtcgagccaccatattcgaagacacttcaaagaatcaacttatcttgaaattggcctctgtgaccgccgcggacacggccatctactactgtgcgagggtccgtgatgcctacaccgctggacactttgactcctggggcccgggaaccctggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctgggtccacggggnttcttcccccag 10881 JY8QFUQ01CU33R No results 10882 JY8QFUQ01DCLUF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10883 JY8QFUQ01A4PSY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 90 to 92 in the user submitted sequence), (do not cause frameshift); agcctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10884 JY8QFUQ01A02L1 unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 408 80.65 100/124 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10885 JY8QFUQ01AKXI3 No results 10886 JY8QFUQ01BH47R No results 10887 JY8QFUQ01APBLB productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 191 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDXFDTW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacncttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10888 JY8QFUQ01ARLVF productive Homsap IGHV3-7*01 F 837 87.56 190/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatcccctgacccagccccaaggtcttccgctgcagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10889 JY8QFUQ01AHUH3 unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 413 80.8 101/125 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca 10890 JY8QFUQ01DA7QX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10891 JY8QFUQ01DIHNN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDS## out-of-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttgggggcctgggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 10892 JY8QFUQ01AKX15 productive Homsap IGHV3-7*03 F 886 90.28 195/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + tctggattcacctttagtagttattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10893 JY8QFUQ01DAACI productive Homsap IGHV3-74*03 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARGTNAVLADPMDYW in-frame - gcctctggattcacctttagtgactactggatgcactgggtccgccaagttccagggaaggggctggtttgggtctcacgcattaaaactgatgacacatctataacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatacgttgtttctgcaaatgaacgatctgagagttgacgacacggcggtgtattattgtgcaagagggacgaacgctgttctggctgaccccatggactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10894 JY8QFUQ01A35H8 No results 10895 JY8QFUQ01CTZBP productive Homsap IGHV4-39*02 F 921 90.58 202/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [2.17.38.11] CARPGARETNNAWVDW in-frame - tctctctggtggctccgtcagtaggagtgcctactactggggctggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10896 JY8QFUQ01CFF78 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10897 JY8QFUQ01AJASK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10898 JY8QFUQ01C0BE5 productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggcccaagggaacccgtggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10899 JY8QFUQ01B5JSV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10900 JY8QFUQ01A4O1N unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARRDVGLHAFDL## out-of-frame + ttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattattgtgcgagacgggacgtaggtttacatgcttttgatctgtggggcccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10901 JY8QFUQ01CBET4 productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 869 86.78 197/227 nt 86.34 196/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 10 12 8.10.12 [2.17.38.11] CSYFRHEPYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tagacgctggattcgcctctggtgattatgctatgagttggttccgccaggctccgggaaAaggggctggagtgggtggggttcatcagaagcagagcttacactgggacaccagaatacgccgcgtctgtgaaaggcagattcaccatctccagagatgcttccaaaagtattggctatctgcaaatgaacaatctgaggatcgaggacacagccgtctattattgctcttattttcggcatgagccatatcactttgactattggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10902 JY8QFUQ01CVT72 unproductive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccaagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10903 JY8QFUQ01BO0WM No results 10904 JY8QFUQ01BMY9S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKGLGPRYYYYGLDVW in-frame + cctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatctattgatggtcgggctactaccccatatcacgcagagtccgtgaagggccggttcaccatctccagagacaattccaacaacacactgtatctgcaaatgaacagcctgagagccgaggacgcggccgtctattattgtgcgaaaggattggggcctcggtattattactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10905 JY8QFUQ01BRADB No results 10906 JY8QFUQ01A0939 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt 92.89 209/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctggGgaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10907 JY8QFUQ01DLKIA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD3-16*01 F 3 8 7 10 8.7.10 [1.17.38.11] CARLDGALRSLG in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacggggcacttcgatctctgggggcccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10908 JY8QFUQ01A1IYG productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10909 JY8QFUQ01B8OAF No results 10910 JY8QFUQ01CJCGS No results 10911 JY8QFUQ01CHCVN No results 10912 JY8QFUQ01BO5DQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10913 JY8QFUQ01C97XU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10914 JY8QFUQ01CPGIE unproductive (see comment) Homsap IGHV1-69*08 F 911 92.45 196/212 nt 91.51 194/212 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.16.38.11] CARDSNGYSSGYIDCW in-frame - stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tggaggctccttcggcagctacactatcacctgggtgcgacaggccctgacaagggcttgagtggatggGgaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 10915 JY8QFUQ01B7HV5 productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10916 JY8QFUQ01B8S9W productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10917 JY8QFUQ01AFSB1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + cctctggattcacctttagcaactttgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10918 JY8QFUQ01AVEBS productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10919 JY8QFUQ01BLH4H unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10920 JY8QFUQ01BCQ7F productive Homsap IGHV3-7*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10921 JY8QFUQ01DI568 No results 10922 JY8QFUQ01CD5BR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 146 53.26 98/184 nt 52.72 97/184 nt 8 8 X 8.8.X [1.16.27.X] null + No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagttactggatgaactgggtccgccaagctccagggaagggctggtatgggtctcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 10923 JY8QFUQ01CBORW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSDYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcagttttagttcttatggcatgaactgggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaGggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10924 JY8QFUQ01B526Q productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10925 JY8QFUQ01AYG87 productive (see comment) Homsap IGHV3-30*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 209 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10926 JY8QFUQ01BYHU2 unproductive Homsap IGHV3-48*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CARARRTISGVVFIEHYGYD#W out-of-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaggacccatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcattcattagtagtagtagtggtaccatattttatgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactttatctgcaaatgaacagcctgagagacgaggatgcggctgtgtattactgtgcgagagcccgtaggacgatttctggagtggtttttattgagcactacgggtatgactctggggcccagggaccacggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 10927 JY8QFUQ01AIE5M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactcacttccccgaaccgtgacggtgtcgtggaactcagg 10928 JY8QFUQ01B9WE3 unproductive Homsap IGHV3-74*03 F 1031 97.25 212/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CATGPDYAYAM## out-of-frame + cctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtggggtccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 10929 JY8QFUQ01C9CX6 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10930 JY8QFUQ01A1DDW productive (see comment) Homsap IGHV4-59*02 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 8 7 15 8.7.15 [2.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'TGGTCGC' (7 nucleotides at position 24 to 30 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagTGGTCGCttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctAccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 10931 JY8QFUQ01B51BA No results 10932 JY8QFUQ01ANYII productive (see comment) Homsap IGHV1-2*02 F 790 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); tggatacattttcaccgGgctactatttacactgggngcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10933 JY8QFUQ01CYFJ0 No results 10934 JY8QFUQ01DB9MD unknown (see comment) Homsap IGHV3-7*01 F 1041 96.82 213/220 nt 96.36 212/220 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10935 JY8QFUQ01B8BDH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 10936 JY8QFUQ01BK7H0 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 185 100.0 37/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcaccttcagtgactactacatgaactgg 10937 JY8QFUQ01CW0ZP No results 10938 JY8QFUQ01AQGFK productive (see comment) Homsap IGHV3-7*01 F 952 94.37 201/213 nt 93.43 199/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [0.17.37.11] CAISSAYFSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) tggattcacctttagtaaccattggatgagttgggtccgccaagctccagggaaggGggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10939 JY8QFUQ01ANO3L productive (see comment) Homsap IGHV4-4*07 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 7 11 8.7.11 [2.17.38.11] CAARNGNVAFNIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); gtctctggCgggctccatctatagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgaatctattccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacaagtccaagaaccagttctccctgaagctgaagtctgtgaccgccgcggacacggccgtgtattactgtgcggcgagaaatggaaatgtggcttttaatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10940 JY8QFUQ01A6KQQ productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10941 JY8QFUQ01AD65Y productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10942 JY8QFUQ01DKITI No results 10943 JY8QFUQ01BFWAR productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 10944 JY8QFUQ01A9VMG productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 861 88.18 194/220 nt 87.73 193/220 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVSDRELHYQHLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); agcgtctggattcaacttcaatagttTttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10945 JY8QFUQ01DCNOJ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRSGQAVGY## out-of-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 10946 JY8QFUQ01B56O6 No results 10947 JY8QFUQ01ALTZA productive (see comment) Homsap IGHV3-66*02 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttggtccgccaggctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10948 JY8QFUQ01C344D productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10949 JY8QFUQ01BD0GZ No results 10950 JY8QFUQ01C6LPJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10951 JY8QFUQ01BAUZA No results 10952 JY8QFUQ01DWYUU productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10953 JY8QFUQ01DOMGW unproductive (see comment) Homsap IGHV3-48*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.16.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgaactggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10954 JY8QFUQ01AYR4C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARDILGATRFDYW in-frame + ctctggattcaccttcagcagctatgccatgagctgggtccgccaggctccagggaagggcctggagtgggtctcagctattagtggtattggtgggagtacattctacgcagactccgtgaagggccggttcaccatcaccagagacaattccaacaacacgctgtttctgcaaatgaatagcctgagagccgaggacacggccatatattactgtgcgagagatattctgggagctactcggtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10955 JY8QFUQ01DQ5E1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10956 JY8QFUQ01B8YM6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + cctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10957 JY8QFUQ01BZ7D4 No results 10958 JY8QFUQ01B4T55 No results 10959 JY8QFUQ01A88F1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10960 JY8QFUQ01C69CS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - gcctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10961 JY8QFUQ01AV350 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 854 90.78 187/206 nt 89.81 185/206 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgGggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10962 JY8QFUQ01C5BUB productive (see comment) Homsap IGHV1-69*08 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'GA' (2 nucleotides at position 73 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tggaggctccttcggcagctacactatcacctgggtgcgacagggccctggacaagggcttgagtggatgggGAacggatcaCcccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10963 JY8QFUQ01CG3IN productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10964 JY8QFUQ01BJPU6 productive (see comment) Homsap IGHV3-11*01 F (see comment) 770 83.94 183/218 nt 83.49 182/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctctggattcagcttaagtgactactacatgacctgggtccgccaggGccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaccgtctccagggacaacgtccaaaactcactgtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10965 JY8QFUQ01A6PTZ productive (see comment) Homsap IGHV3-11*04 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRLYDSSGYDFGELGDYSDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); ctctggattcaacttcagtgactactaGcatgacttgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtgctagtggtggtaccataaaatacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtttctgcaaatgaacagcctgagggccgaagacacggctgtatatttttgtgtgagagatcgtctctatgatagtagtggttatgactttggggaattgggggactattcagaccactggggccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10966 JY8QFUQ01CAN38 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1071 99.54 216/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*03 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacttttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 10967 JY8QFUQ01DNV7F productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcaccttcagtagccatgctatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacgctatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10968 JY8QFUQ01AF9TM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 91.24 198/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-3*01 F 2 7 8 X 7.8.X [1.17.38.11] CARGGLEPVDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 39 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) cctctggattcaccttagtacatactggatgcactgggGTccgcccaagctccagggaaggGggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10969 JY8QFUQ01C5M5K unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 351 62.21 135/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (62,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ttctggattctcctttagcaactatgccctggcctgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10970 JY8QFUQ01DIDA9 No results 10971 JY8QFUQ01B17HS productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPRSVSRYSLFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatttttgtgcgagagatcctcgttccgtgagcagatactctttatttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10972 JY8QFUQ01B7D6Q productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10973 JY8QFUQ01BABPJ No results 10974 JY8QFUQ01ARYXD productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10975 JY8QFUQ01AJ6O8 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGPGITTV#DAFDVW out-of-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgaggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10976 JY8QFUQ01CHVQB No results 10977 JY8QFUQ01CHX0H productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*04 F 993 96.26 206/214 nt 95.79 205/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-15*01 F 2 8 7 21 8.7.21 [1.16.38.11] CARRIQGHCRGGSCSRNNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcagtggttactactggagttggatccgccagccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaactcgtccctcaagagtcgagccaccatctcagtagacacgtccaagaagcagttgtccctgaacgtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacggattcaaggacattgtaggggtggtagttgctccaggaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10978 JY8QFUQ01DUOGR No results 10979 JY8QFUQ01C3PLL unknown (see comment) Homsap IGHV3-30*15 F 896 90.37 197/218 nt 89.91 196/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtaGaaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactacttttgactattgggggccagggaaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaggag 10980 JY8QFUQ01DLLPI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAKDRVLSGGPDYW in-frame + ctctggattcatctttagcaattttgccatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcaagtatcagtcgttacggtggaagctcaaaccacgcagactccgtcaagggccggttcaccatttccagagacaatggcatgaacacgctgtttcttcaaatgaacagcctgagagccgaggacacggccatatactactgtgcgaaagatcgagtcttaagtgggggccctgactactggggccagggagtcctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 10981 JY8QFUQ01DAX0I productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10982 JY8QFUQ01DO1JM unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10983 JY8QFUQ01BVU4U No results 10984 JY8QFUQ01DMXRX unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*05 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*07 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69*14 F or Homsap IGHV1-69D*01 F (see comment) 413 73.12 117/160 nt 71.25 114/160 nt 7 8 X 7.8.X [X.15.22.X] null - No rearrangement found Low V-REGION identity (73,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 56 of V-REGION: 'GA' (2 nucleotides at position 71 to 72 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 70 in the user submitted sequence), (do not cause frameshift) aggcaccttcagtagttacgcaatcagctgggtgcgacaggccctgggcaagggcttgagtggatgggggGAtcatccctaagtttggaagaacaaactacgcacagagtttccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10985 JY8QFUQ01AI30F No results 10986 JY8QFUQ01DKKST productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacactgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10987 JY8QFUQ01CWQNK productive Homsap IGHV1-3*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGESLGGDYFDYW in-frame + tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 10988 JY8QFUQ01BAZT3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10989 JY8QFUQ01DO347 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 10990 JY8QFUQ01BL0EE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 10991 JY8QFUQ01AC7OR productive Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 10992 JY8QFUQ01AH7MF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10993 JY8QFUQ01AZ8UY unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 817 87.32 186/213 nt 86.85 185/213 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 6 X 8.6.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttcttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10994 JY8QFUQ01BH3GK productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccaggcacccagagaaggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 10995 JY8QFUQ01DEJ3A productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 10996 JY8QFUQ01B06AQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10997 JY8QFUQ01BNY8P productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 10998 JY8QFUQ01A00NG unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 125 100.0 25/25 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tccggggacagtgtctctagcaaca 10999 JY8QFUQ01CIPYX productive Homsap IGHV3-7*03 F 945 93.09 202/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11000 JY8QFUQ01CCEYG productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccaggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 11001 JY8QFUQ01DQFDK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11002 JY8QFUQ01C5QUT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11003 JY8QFUQ01BWZC8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 34 of V-REGION: 'ACC' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift); gtctttggtgactctctgagtACCagtagcagtttctactggggctgggtccgccaggccccagggaagggactggagtgggttgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccaaaaccaggtctccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11004 JY8QFUQ01BXP0X No results 11005 JY8QFUQ01BBXYO productive Homsap IGHV1-2*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAKVSSTRTAGLYFDYW in-frame - tggatacaccttcaccggctcctatatgcactgggtgcgacaggcccctggacaaggccttgagtacataggatggatcaaccttaacagtgctggcacaaattatgtacagaggtttcagggcagggtcaccatgaccagggacacgtccattaccacagcctacatggagctgagccggctgacatctgacgacacggccgtgtattactgtgcgaaagtatcctcgacaagaacagctggcctttactttgattactggggccagggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11006 JY8QFUQ01A14J8 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 915 90.91 200/220 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [2.17.38.11] CARGKDTGMGSHGMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctgctggattcaccttcactaatcatcgtatgcactgggtccgccaggctccaggcaaggggctagagggggtggcagttatttcatatgatggaaggaataaatactatgcagactccgtgaagggccgattcaccatctccagagaaaattccaacaaaacgttatatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgagaggaaaggatacaggtatgggttcgcacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11007 JY8QFUQ01DHSA2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1022 96.79 211/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 7 11 8.7.11 [2.16.38.11] CVVQILGATIDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) ggcctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccatagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11008 JY8QFUQ01DJR2Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - tctggattcacctttagcatctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcgactattagtggtagtggaaatagtacataccatgcagactccatgaagggccggttcaccctctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11009 JY8QFUQ01CK8EK No results 11010 JY8QFUQ01A7KXL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11011 JY8QFUQ01B312C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 11012 JY8QFUQ01CXKUT unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11013 JY8QFUQ01C3QFI unproductive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 868 89.35 193/216 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CSSGGDYPN## out-of-frame - tctggattcgacttcgatggccgtgctatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctcatatgatggaaatgataaaaactacgcagactccgtgaggggccgattcaccatctccagagacaattctaaggacacgctgtttttgcaaatgaacagcctgagacatgaagacacgggtgaatatttctgttcttcaggaggtgactacccgaactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11014 JY8QFUQ01C13BC unproductive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggatttacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 11015 JY8QFUQ01BGAKE productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + cctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11016 JY8QFUQ01AELH5 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRALDSSGHYIDI## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatgagcagtggtaattactgctggggctggggccgccagcccccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11017 JY8QFUQ01CL3FT unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 830 86.43 191/221 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [1.17.38.11] CARAGGWT#YFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactatgctggggccaccaacctcgccccctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggacccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11018 JY8QFUQ01AOEER productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 847 87.67 192/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactgGggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatGagtatggggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11019 JY8QFUQ01AKI3P productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt 84.16 186/221 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] CTRQGPYLYGFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); tctctggtgtttccgtcagtaacactGattttctattggggTctgggtccgccagtccccagggaagggactggagtggattggcagtgtagattatagtgggagcgcttcctacagccctgccctcaagagtcgagtcatcatatccatagacacgtccaagaaccagttctccatagctctgagttctgtgaccgccgcagacacggctgtctattattgtacgagacagggaccctacctctacggtttcgacgtctggggccaagggaccacggtcaccgcctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 11020 JY8QFUQ01DE6DM productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11021 JY8QFUQ01DS7CO unproductive (see comment) Homsap IGHV3-9*01 F 460 90.99 101/111 nt 90.09 100/111 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [2.15.11.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) agcctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11022 JY8QFUQ01BSOS8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11023 JY8QFUQ01BDIQ1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) gcctctggattcaccctttggttatatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11024 JY8QFUQ01DNPQB No results 11025 JY8QFUQ01A3R46 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcaccttcagtgactatcacatgtactgg 11026 JY8QFUQ01BB77N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccGagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11027 JY8QFUQ01CR1LS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11028 JY8QFUQ01BN59C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt 83.87 182/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARRSGRDGGWFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 137 to 137 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'TC' (2 nucleotides at position 154 to 155 in the user submitted sequence), (cause frameshift); ctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccCctctacaaagacggttTCcaaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11029 JY8QFUQ01BA6L3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11030 JY8QFUQ01DBPDU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + gttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggctcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11031 JY8QFUQ01CJ93A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11032 JY8QFUQ01AMLRB No results 11033 JY8QFUQ01AMWF5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'T' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttatagcatgaactgggtccgccTgggctccagGggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11034 JY8QFUQ01COCGB unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 11035 JY8QFUQ01C0SS1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11036 JY8QFUQ01B1N7G productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 867 87.44 195/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 10 12 8.10.12 [1.17.38.11] CSYFRHEPYHFDYW in-frame + cgctggattcgcctctggtgattatgctatgagttggttccgccaggctccgggaaaggggctggagtgggtggggttcatcagaagcagagcttacactgggacaccagaatacgccgcgtctgtgaaaggcagattcaccatctccagagatgcttccaaaagtattggctatctgcaaatgaacaatctgaggatcgaggacacagccgtctattattgctcttattttcggcatgagccatatcactttgactattggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11037 JY8QFUQ01AP2Y1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*01 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGVGAYYIYYFDLW in-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatggggccaaggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11038 JY8QFUQ01BS9NH productive (see comment) Homsap IGHV4-39*03 F 924 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11039 JY8QFUQ01BU9BZ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagGttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11040 JY8QFUQ01ANERH productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGPGGGWYAEQW in-frame + ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgggccggggggtggctggtacgctgagcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11041 JY8QFUQ01BF786 No results 11042 JY8QFUQ01B7IID productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11043 JY8QFUQ01C9X3S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11044 JY8QFUQ01CPQ3H productive Homsap IGHV3-7*01 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-3*02 F 2 8 8 16 8.8.16 [2.17.38.11] CARQFRSGNTDYFGLDVW in-frame - cagcctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcaccatctccagagacaatgacaagaactcattgtatctgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgcgagacagtttcgtagtggtaatacagactacttcggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11045 JY8QFUQ01DMPJE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 873 89.4 194/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] YAKDQSCIVGPCGFDY## out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactatgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11046 JY8QFUQ01CPCDK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.37.11] CARDSGMFCNSGSCYVYYGPDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcttcttcagcagttttggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggcagtcacatcatatgatggaggtaataaattttatggagactcagcgaagggccgattcactatctccagagacaattccaaaacacactgtatctgcaaatgaacagactgacaactgaggacacggctacttattactgtgcgagagattcggggatgttttgtaacagtggtagttgctacgtctattacggcccggacctctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttc 11047 JY8QFUQ01DUXRT productive (see comment) Homsap IGHV4-39*03 F 922 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 6 17 9.6.17 [0.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) ccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11048 JY8QFUQ01AVL1I unproductive Homsap IGHV4-59*03 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARYYFASGILTSGSFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaataattattactggggctggattcggcAaccccccagggaagggactggaatggattgggtatatccaccacagtgggagcaccaactacaatccctccctcaagagtcgattcaccatgttagtcgacacatcccagaatcaattctccctgaaattgaattccgtgaccgctgcagacacggccatatatcgctgtgcgagatattacttcgctagtggaattcttacgtcggggagctttgactactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11049 JY8QFUQ01AKIEX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 762 83.18 183/220 nt 82.73 182/220 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.37.11] CARRWSGTYPFASW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 210 in the user submitted sequence), (cause frameshift) tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagtcccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggcttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11050 JY8QFUQ01A7XVM No results 11051 JY8QFUQ01CMVR1 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccagttttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11052 JY8QFUQ01CSJ98 productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11053 JY8QFUQ01A39TZ No results 11054 JY8QFUQ01BT5S9 productive Homsap IGHV4-39*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11055 JY8QFUQ01APQ85 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + ctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11056 JY8QFUQ01C33ZE No results 11057 JY8QFUQ01AR7NH productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11058 JY8QFUQ01A30ZP No results 11059 JY8QFUQ01B6G9V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11060 JY8QFUQ01CG7RL unknown (see comment) Homsap IGHV3-13*02 F, or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-35*01 ORF or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 87 90.48 19/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcacatttagtaa 11061 JY8QFUQ01BAJIQ No results 11062 JY8QFUQ01ANRI3 unknown (see comment) Homsap IGHV3-23*05 F 90 49.28 102/207 nt 8 8 X 8.8.X [1.17.34.X] null - No rearrangement found ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaagggactggttcgaccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11063 JY8QFUQ01BPU64 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 944 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARHAQYYYDSSGYYYLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'GA' (2 nucleotides at position 70 to 71 in the user submitted sequence), (cause frameshift); tggagtacaggctttaccagctactggatcggctgggtgcgccagatgcccgggaaaaggcctgantggGAtgggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagacacgcgcagtattactatgatagtagtggttattactacttagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11064 JY8QFUQ01BC33J productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11065 JY8QFUQ01AN5X2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.16.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift) tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcncatgcctggtccagggcttcttccc 11066 JY8QFUQ01CFWDU productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11067 JY8QFUQ01A62Y2 productive (see comment) Homsap IGHV1-18*01 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'GC' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); tggttacacctttactacctatggGCgtcaccctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11068 JY8QFUQ01B0MEN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcc 11069 JY8QFUQ01DLF2L productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 871 90.14 192/213 nt 89.67 191/213 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.16.38.11] CAREFRAPSLARYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11070 JY8QFUQ01BXKLZ No results 11071 JY8QFUQ01CDA18 productive Homsap IGHV4-61*02 F 830 86.43 191/221 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*01 F 2 10 7 19 10.7.19 [1.17.38.11] CAREAPKTAGDSYGSLAMDVW in-frame + tctctggtggctccgtcagtagtggttcttactactggagctggacccggcagcccgccgggaagggactggagtggattgggcgtgtccacagcggtggcagttccgactacaacccgtccctcacgggtcgagccaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgagtatttctgtgcgagagaggcgcccaagacagcaggtgattcctacggctctctcgctatggacgtctggggccaagggaccacggtcatcgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttcccccc 11072 JY8QFUQ01BDJ01 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 11073 JY8QFUQ01A1RU8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 928 93.81 197/210 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 7 8 16 7.8.16 [X.17.38.11] CARGRIVSVGMSGWFDPW in-frame - ttcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11074 JY8QFUQ01A9A38 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tctctggtggctccatgagcagtggtaattactgctggggctggggccgccagcccccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtCcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11075 JY8QFUQ01AZ4IH productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame - ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11076 JY8QFUQ01AX6UQ No results 11077 JY8QFUQ01CSMNR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11078 JY8QFUQ01BHGDW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11079 JY8QFUQ01DOLHE No results 11080 JY8QFUQ01A7QNQ productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11081 JY8QFUQ01BA7U2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctgggttcacattcagtaactactggatccactgggtccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactgggggccagggaaccccgtgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11082 JY8QFUQ01C4MXA unknown (see comment) Homsap IGHV4-30-2*01 F, or Homsap IGHV4-30-2*02 F or Homsap IGHV4-30-2*03 F or Homsap IGHV4-30-2*05 F or Homsap IGHV4-30-2*06 F 103 70.45 31/44 nt 68.18 30/44 nt X X X X.X.X [14.X.X.X] null + No rearrangement found stop codons in FR1-IMGT, from codon 7 of V-REGION: 6 nucleotides (from position 128 in the user submitted sequence), (do not cause frameshift) tggggaagaagccctggaccaggcatgcgacgaccacgttcccatcttgggggtgctgtcgaggctcagcgggaagaccttggggctggtcggggatgctgggggctggcggatgcagttccaggagtaaccactgaaggacccaccacagac 11083 JY8QFUQ01A1Y2H productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [0.17.38.11] CAKVGNLYFFEYW in-frame - tggattcagcttcagtagctacagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatctattagcaccaccagtagtaccataggctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11084 JY8QFUQ01ACOQH unproductive Homsap IGHV4-61*02 F 978 94.09 207/220 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARVRARSNSHPGHSWFD#PW out-of-frame + ctctggtggctccatcagcagcagtagttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaaccggtgacggtgtcgtggaactca 11085 JY8QFUQ01ADHG3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11086 JY8QFUQ01CP5Y2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11087 JY8QFUQ01DLJGF productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD5-12*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDQRDYDYIYYYGMDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); ctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtactTatgcagacttcgtgaagggccgattcaccatcaccagggacaattcccagaacactctgtctctgcaattgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacgggatggacctctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11088 JY8QFUQ01CF3EH No results 11089 JY8QFUQ01A8IOY productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11090 JY8QFUQ01B8XC4 No results 11091 JY8QFUQ01DQ77V productive Homsap IGHV3-11*01 F 987 94.55 208/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - agcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11092 JY8QFUQ01C4GBD No results 11093 JY8QFUQ01AGWHU productive (see comment) Homsap IGHV3-48*01 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11094 JY8QFUQ01BRTEE productive (see comment) Homsap IGHV3-7*01 F 891 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgagGaaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggatacttccccgaaccggtgacggtgtcgtggaactcagg 11095 JY8QFUQ01BZKWG No results 11096 JY8QFUQ01B59AU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca 11097 JY8QFUQ01B5XZZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.37.11] CAKVSGNSRTYWYLDIW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 86 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctGgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacacgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11098 JY8QFUQ01CI8E6 productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11099 JY8QFUQ01BKBYB productive (see comment) Homsap IGHV4-39*03 F 918 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 6 17 10.6.17 [0.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) ccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11100 JY8QFUQ01AXJHF unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNG#DFW out-of-frame + tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacgggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11101 JY8QFUQ01CX33A productive Homsap IGHV3-7*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatcttcagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag 11102 JY8QFUQ01BNGRJ productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + tggatacaccttcaccagttactatatgcactgggtccgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11103 JY8QFUQ01AXNJJ No results 11104 JY8QFUQ01DET16 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11105 JY8QFUQ01BGTBC No results 11106 JY8QFUQ01BHSYH productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11107 JY8QFUQ01AVDQK productive Homsap IGHV3-7*03 F 967 94.44 204/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKEIAVSGEGRGLL in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgaggggcgtggacttctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11108 JY8QFUQ01B6JUY No results 11109 JY8QFUQ01ALDM8 No results 11110 JY8QFUQ01C6Z5P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 953 93.95 202/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagccccacgggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 11111 JY8QFUQ01CHP7M unproductive Homsap IGHV3-7*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.16.38.11] CATSPFTVTTGKDAY## out-of-frame + in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) ctctagattcacctttaggacatattggatgagttggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 11112 JY8QFUQ01CKJ8C No results 11113 JY8QFUQ01BLUE2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 147 52.11 111/213 nt 8 8 X 8.8.X [1.17.36.X] null - No rearrangement found ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgaagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 11114 JY8QFUQ01CPVDU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1005 95.45 210/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - ggcctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11115 JY8QFUQ01CLAMG productive Homsap IGHV4-61*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + ctctggtgactccattagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11116 JY8QFUQ01ALAXK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11117 JY8QFUQ01DKCDX productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11118 JY8QFUQ01CQK1A No results 11119 JY8QFUQ01CY9AT unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11120 JY8QFUQ01DBHC6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11121 JY8QFUQ01DD3NG productive (see comment) Homsap IGHV4-61*02 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARAWNGDYEVGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); ctctgtgactccatcggtaatggaagttactactggagctAgggtccggcagtccgccgagaagggactggagtggattggacatatctataccagagggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagccgacacgtccaagaatcagatctccctgaagttgacctctgtgaccgccgcagacacggccgtatattactgtgcgagggcgtggaacggtgactacgaggtgggctggttcgacccctggggccaggggaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11122 JY8QFUQ01BFUTU No results 11123 JY8QFUQ01DHFDA productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccGttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11124 JY8QFUQ01AKGE1 unproductive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1078 98.65 219/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [2.17.38.11] CARDRGP*QLVQNGI#DYW out-of-frame - stop codons gtctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcgggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11125 JY8QFUQ01AIXTO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 348 96.0 72/75 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found tctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctca 11126 JY8QFUQ01ATFWJ productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11127 JY8QFUQ01A9LDO productive (see comment) Homsap IGHV3-7*01 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'TT' (2 nucleotides at position 15 to 16 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); cctctaaattcaccTTtttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaAagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11128 JY8QFUQ01CTV37 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11129 JY8QFUQ01CVMEU No results 11130 JY8QFUQ01BVR5D unknown (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found ctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11131 JY8QFUQ01A37SY No results 11132 JY8QFUQ01B8KMJ unproductive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 X 10.7.X [1.17.38.11] CARCPNYNIGTRG#FDYW out-of-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccggggggctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11133 JY8QFUQ01ARU4K productive (see comment) Homsap IGHV4-4*07 F 1052 99.07 213/215 nt 97.21 209/215 nt Homsap IGHJ1*01 F (see comment) 197 86.54 45/52 nt Homsap IGHD6-13*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARTAAAGQFDPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctgggtgctccatcaGgtagttactacCtggagctgGgatccggcagcccgGccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgaggaccgcagcagctggacagttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11134 JY8QFUQ01BX232 No results 11135 JY8QFUQ01AVH6A productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.15 212/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11136 JY8QFUQ01C3JR0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11137 JY8QFUQ01B5B8P unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 810 85.71 186/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11138 JY8QFUQ01CD1M7 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 11139 JY8QFUQ01AUTBM unknown (see comment) Homsap IGHV3-21*04 F (see comment) 720 81.11 176/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11140 JY8QFUQ01AXF50 unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 1 9 7 X 9.7.X [1.17.38.11] CARDQRADLAPRQ#FDYW out-of-frame - tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgtgcgagagatcagcgggccgatttggcacctcgtcaacctttgactactggggccagggagcccaggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11141 JY8QFUQ01BC5YA productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11142 JY8QFUQ01DG2MU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11143 JY8QFUQ01CSS8X productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11144 JY8QFUQ01BKEKF No results 11145 JY8QFUQ01B5KVE unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 138 64.1 50/78 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 11146 JY8QFUQ01AI7P6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 743 82.57 180/218 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARTPCSGGNCYLRGHDLW in-frame + Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcgggtatttattattgtgcgcggacgccttgcagtggtggaaattgttaccttagaggccacgacctctggggccagggaacccaggtctccgtttccccagcagtccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga 11147 JY8QFUQ01B2H3D productive Homsap IGHV4-61*02 F 897 90.0 198/220 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARAKVVIRPNWFDPW in-frame - ctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagcaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11148 JY8QFUQ01CIBG4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CARWRGQQSEMEYW in-frame - gcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 11149 JY8QFUQ01C5WRD No results 11150 JY8QFUQ01CMI8I productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11151 JY8QFUQ01BE69W productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcacgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11152 JY8QFUQ01BECQV No results 11153 JY8QFUQ01C4C7K unproductive Homsap IGHV3-11*01 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDLYGADDL# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcccctttaaggactactccatgaactggatccgccaggctccagggaagggactggagtggAttttcatacatgagcagcactggtgagaccatatattacgcggactttgtgaagggccgattcaccatctccagggacaccgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccgagggcttcttcccccag 11154 JY8QFUQ01BPMR5 productive (see comment) Homsap IGHV3-48*02 F 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVTERGGGLLRYLDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); gctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccaggGgaaggggctggagtggAttttcatatattagtagcagtagtcaaacgatttactacgcaaactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactgtgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11155 JY8QFUQ01CHCL3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11156 JY8QFUQ01BTY4N No results 11157 JY8QFUQ01ACHVK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctcctggattcaGcattcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11158 JY8QFUQ01AMK5G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11159 JY8QFUQ01AWGJ4 productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtttccccagcatccccgaccagccccaaaggtcttcccgctgagccctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 11160 JY8QFUQ01DFHN2 productive (see comment) Homsap IGHV1-8*01 F 939 93.46 200/214 nt 91.59 196/214 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [0.17.38.11] CARWRLGSGLEGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttatgatatcaattgggtgcgacaggGccactggacaaGgggcttgagtggatgggatggatgagGcccaaacagtactGataaggggctatgcacagaagttccagggcagagtcaccatgaccaggagcacctccataagcacagcctacatggagctgagtagcctgacatctgaagacacggccgtctattactgtgcgagatggcgattgggttcggggcttgagggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11161 JY8QFUQ01A7OD5 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11162 JY8QFUQ01DFOB1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11163 JY8QFUQ01DOMNJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgactccttcagaactcactactggagttggattcgacagcccccgggggaggAgattggaatggattggcaatatatattatattgggaccaccaactacaacccctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11164 JY8QFUQ01AG0SV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggactcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11165 JY8QFUQ01BCOXR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11166 JY8QFUQ01DVSTX unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 11167 JY8QFUQ01CPSV4 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11168 JY8QFUQ01BG5T6 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGYW in-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11169 JY8QFUQ01B6KYS unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11170 JY8QFUQ01ANZL9 No results 11171 JY8QFUQ01A4T3U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [2.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaagggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacgactgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11172 JY8QFUQ01BL4XI productive Homsap IGHV3-33*03 F 855 88.48 192/217 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARADGAGYNYATYYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggattcaacttcaatagtcatgccatacactgggtccggcaggctccaggcaaggggctggagtgggtggcaggtgtttggtatgatggaagtgacaaatactatgcagactcagtggcgggccgattcaccatctcccgagacaactccagaaaaacagtgtttctggaaatgaacagtctgagaggcgaggacacggctgtgtattactgtgcgagagcggatggtgctggttacaactacgcgacgtactactttgattcctggggccagggaacccaggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 11173 JY8QFUQ01DECT5 productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 190 89.36 42/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag 11174 JY8QFUQ01A9S30 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11175 JY8QFUQ01C95PS No results 11176 JY8QFUQ01BH4FT productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 708 81.99 173/211 nt 81.04 171/211 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [0.16.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,99% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 76 of V-REGION: 'C' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaattatcccggcgggagcacattccacgcagactccgtgagggggcgcCgtcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11177 JY8QFUQ01CATEA productive Homsap IGHV4-39*03 F 924 91.32 200/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11178 JY8QFUQ01CZTAK unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*03 F or Homsap IGHV4-34*06 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CASWNTLAYYFGF#W out-of-frame + in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcaggggttatcactggagctggatccgccagtccccagggaaggggctagagtgggttgggAgaaatcgattttggtggaaccaccaagtacaagtcgtccctcaagagtcgagtcaccatatcactagacacggccaagaaccacttctcgttgaacctgcgctctgtgaccgccgcggactcgggagtgtattactgtgcgagttggaatactctggcttactactttggattcttggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtnaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11179 JY8QFUQ01CVJA3 productive (see comment) Homsap IGHV3-7*01 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11180 JY8QFUQ01CQG0I unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 885 88.79 198/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 10 X 8.10.X [1.17.38.11] CTTRPRGGNHLA#DYW out-of-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggttggccttattaagaccaaacctgatggttggacaacaatctactctgcacccgtgaaaggcagattcatcatttcaagagatgattcaaaaaacatggtgtttctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtaccacacggccccggggtgggaaccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11181 JY8QFUQ01BTFVE productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tctctggtggcGtccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtGgggggcaccaattacaacccgtcCcctcgagagtcgagtcactatatcagtagacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagaaacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11182 JY8QFUQ01DA2KM productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 11183 JY8QFUQ01AWOU0 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggGactctgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11184 JY8QFUQ01CRKTD productive (see comment) Homsap IGHV3-7*01 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDSPSAYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); cagcctctggattcaGcctttagtttatCactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11185 JY8QFUQ01C50GB No results 11186 JY8QFUQ01BKGXH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKYVEGWS*YGGLL##SYAMDVW out-of-frame + stop codons ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatgatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11187 JY8QFUQ01BN3SN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 912 90.13 201/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - tgtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11188 JY8QFUQ01CJXQH productive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11189 JY8QFUQ01ACVQ4 productive Homsap IGHV4-4*07 F (see comment) 683 80.0 172/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARESTNSIGDPRHLDSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01ACVQ4 ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggccccatcaacacacatgacttctattggacgtggatccggcagtccgccgggaggggactggagtggctcggacgtgtctatatgaatggcattagtgaccacaatccagtcttcactagtcgtctcaccatgtccattgacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggactcggccctatattactgtgcgagagaaagtactaattcgattggcgacccgagacaccttgactcttggggccagggaaggttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 11190 JY8QFUQ01APAUY unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found cctctggattcatcttcagtagctactggatgcactggg 11191 JY8QFUQ01B6PJY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 724 81.48 176/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11192 JY8QFUQ01C0LHV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*02 F 1 8 8 16 8.8.16 [1.17.38.11] CAKDPQQLLEDINWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); ctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaagggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccggttcaccatctccagagacaacgccaggaacacAtttttatctgcaaatggacagcctcagagccgaggacacggccgtctattactgtgcgaaagatcctcagcagttattggaagacataaactggttcgacccctggggccagggcacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11193 JY8QFUQ01DFINT productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLPGWTGYFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); ctctggtttcatcttcagtgtctatAcccatgcactgggtccgccaggcgccaggcaaggggctagagtgggtggcacttatatcatataatggaggtaatacatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaatgggctgagaactgaggacacggctgtttattactgtgcgagagatctgccaggctggacaggctactttgaccactggggccagggagccctgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11194 JY8QFUQ01AIZWZ productive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11195 JY8QFUQ01B6T6U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11196 JY8QFUQ01B6SGU productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaaaaaaagtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11197 JY8QFUQ01BNP6J productive Homsap IGHV3-7*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSRSPANW in-frame - cctctggattcacctttagaagctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaattcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11198 JY8QFUQ01B9XU2 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 974 93.67 207/221 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD5-18*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARSQSRYSWGDFLHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgactccatcagcagtactagttactactggggctggatccgccagcccccagggagggggctggagtggattggaagcatctattatagtgggagcacctcctacaacccgtccctcaagagtcgaatcaccatgtccatagacatgtccaagaaccaattctccctgaggctgagctctgtgaccgccgcagacacggctgtttatttctgtgcgcggtcccagagtagatacagttggggtgacttcttacactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 11199 JY8QFUQ01C3PST productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [2.17.37.11] CVRGGVSGAFRWGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 107 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11200 JY8QFUQ01DPHN5 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F (see comment) 204 78.79 52/66 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (78,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcagtacctatgcaatgcactgggtccgccaggctccagggcttcttccccc 11201 JY8QFUQ01CGUTY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'GG' (2 nucleotides at position 125 to 126 in the user submitted sequence), (cause frameshift); ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaagGGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11202 JY8QFUQ01BQNV9 No results 11203 JY8QFUQ01AUUSZ productive Homsap IGHV3-48*03 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11204 JY8QFUQ01CJ7YK productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11205 JY8QFUQ01A02KS productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARGGQRTGWYEYW in-frame + ctctggattcacctttagtacctattggatgacttgggtccgccaggctccagggaaggggctggagtgggtggccagcataaaaaatgatggaagtgagaaatcctatgtggactctgtaaagggccgattcaccatctccagagacaacgccgagaactcactgtatttgcaagtgaacaacctgagagccgaggacacggctgtatattactgtgcgagagggggccaaagaactggctggtacgaatattggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 11206 JY8QFUQ01DRIF5 unproductive Homsap IGHV3-9*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKMILVSGWSDL#LDYW out-of-frame + ctctggattcaagtttgatgattatgccgcgcactgggtccggcaagctccagggaagggcctggaatgggtctcaggtattagttggaatggtggtagcacacgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgccctgtatctggaaatgaacattctgagaactgacgacacggccttatattactgtgcaaaaatgattttggtcagtggctggtcggacctttttggactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11207 JY8QFUQ01COP99 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + tctggatacatgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11208 JY8QFUQ01BUR31 No results 11209 JY8QFUQ01A3VOS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 11210 JY8QFUQ01CIYMG No results 11211 JY8QFUQ01CZGL0 No results 11212 JY8QFUQ01CJ3GU productive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [2.17.38.11] CTKVVGGYDTADYW in-frame - gcctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaacgaagatggaagagcgcaaaactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggatacggctgtgtattactgtacgaaagtcgtcggtggctacgatactgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11213 JY8QFUQ01DCW32 unproductive Homsap IGHV3-48*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [1.17.38.11] CARDAHFGRYY#FDLW out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'ACT' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); cctctggattcacctttagcacctatagcatgcactgggtccgtcaggctccagGggaaggggctcgaatggattgcatacattagtACTagtactactagtcccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgccgataactcactgtatctgcaaatgaacagcctgagagacgacgacacggctgtttattattgtgcgagagacgcccattttgggagatattattttttgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11214 JY8QFUQ01BT4R4 productive (see comment) Homsap IGHV3-7*01 F (see comment) 747 82.95 180/217 nt 82.03 178/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggattcgtctttactaatcattggatgagttggGgtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11215 JY8QFUQ01DWZTC No results 11216 JY8QFUQ01ACVZU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 8 10 7.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) tctggattcagcttaagttctatggcatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11217 JY8QFUQ01CXYEY unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 243 57.14 124/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (57,14% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatatactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11218 JY8QFUQ01DQ427 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame - tctctggtgactccatcagcagtaatagtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11219 JY8QFUQ01A720R productive Homsap IGHV3-43*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame + cctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 11220 JY8QFUQ01CPBZM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 11221 JY8QFUQ01CD1Z2 No results 11222 JY8QFUQ01BAN07 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRLNW*LHIRR#FDLW out-of-frame + stop codons Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaactggtgactacacattcggcgcattttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggaccanttgcccccgaaccggtgacggtgtcgtggaactc 11223 JY8QFUQ01CDHH3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtGgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11224 JY8QFUQ01BT4AX productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 11225 JY8QFUQ01BR5IZ No results 11226 JY8QFUQ01C7WRQ unproductive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-16*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVIPGRGNYAF*CLG in-frame + stop codons ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgctttttgatgtctgggggccggagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11227 JY8QFUQ01DC7DQ productive Homsap IGHV3-21*04 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11228 JY8QFUQ01CIEOW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttcacctttgatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcag 11229 JY8QFUQ01AH4O3 unproductive Homsap IGHV4-61*02 F 934 91.44 203/222 nt 89.64 199/222 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [2.17.38.11] CARATLSDVDTPMGFDS## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'CT' (2 nucleotides at position 90 to 91 in the user submitted sequence), (cause frameshift); gtgtctggtgactccatcagcagtggGtacttactactGggaactggatacggcagcccgccgggaagGgggctggagtggattgggcgCTtttttataccagtgggagcaccaagtacagcccctccctcaagagtcgagtcaccatatcaggagacacgtccaagaaccaggtctccctgaggctcagtcatgtgaccgccgcagacacggccgtctatttctgtgcgcgagcaacgctgtctgacgtggatacacctatgggttttgactcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg 11230 JY8QFUQ01CE3GK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) agcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11231 JY8QFUQ01ANN3Q No results 11232 JY8QFUQ01CBXI5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11233 JY8QFUQ01A3QP3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame - cctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccatgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11234 JY8QFUQ01AMZ6W productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARVDFYGSSKYKGFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11235 JY8QFUQ01BOIEU productive (see comment) Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11236 JY8QFUQ01AGGTS productive Homsap IGHV3-64*02 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRPMAGFHGILYDNW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggg 11237 JY8QFUQ01C624X unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-15*01 F 3 8 10 X 8.10.X [1.17.38.11] CAADGCPGGTCYHG#LDMW out-of-frame + ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttggatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcncatgcctggtccagggcttcttccc 11238 JY8QFUQ01ANT01 productive (see comment) Homsap IGHV3-33*03 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.37.11] CARAASHGWYLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) gtctggattcatcttcagtggctatggcatgcactgggtccgccaggtcccaggcaagggcctggagtgggtggcggttattcggtatgatggaactaatgatgactatgcagactccgtgaagggccgattcaccatctccaaagacacctccaagaacactctctatctgcaaatgaacagcctgaggccgaggacacggctatatattattgtgcgagagcggctagccatgggtggtacctggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11239 JY8QFUQ01BIEF4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.13 199/216 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + tctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11240 JY8QFUQ01A78FD unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*03 F (see comment) 87 64.58 31/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaacctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccctggtaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11241 JY8QFUQ01AI87L productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD3-22*01 F 3 8 10 23 8.10.23 [1.17.38.11] CATDRPYYKKSLLADSGITTVWTFW in-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaatcgctgctggccgactctggtattactacggtatggacgttttggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11242 JY8QFUQ01AK1LD unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CSKTPLGE#DYW out-of-frame - ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccagggaaggggctggagtgggtctcacgtattaatgaagatgggaggactacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacaccaagaacacactgtatctgcagatggacagtctgagagccgaggacacggctgtgtattactgttcaaagacacctttgggggagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11243 JY8QFUQ01COFPE unproductive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 923 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSVPRASEAAYYFDS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtatttattctatgcattgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacggctgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttgggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11244 JY8QFUQ01AJ6ES productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11245 JY8QFUQ01CVDU4 productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11246 JY8QFUQ01CUMN3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.37.11] CVREGAATGSFYYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11247 JY8QFUQ01B3XHO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11248 JY8QFUQ01CEW9N unproductive Homsap IGHV3-64*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaaggGgactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11249 JY8QFUQ01C6YH3 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + cgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11250 JY8QFUQ01BFGVN No results 11251 JY8QFUQ01BM4NU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11252 JY8QFUQ01DXH62 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 152 57.14 76/133 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found stop codons cctctggattcaccttcagtagcctttggatgagctgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11253 JY8QFUQ01CUEJA No results 11254 JY8QFUQ01BRKQG No results 11255 JY8QFUQ01BKUUH productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11256 JY8QFUQ01DCJM7 No results 11257 JY8QFUQ01B8YA9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11258 JY8QFUQ01B56I8 productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 11259 JY8QFUQ01AWAE8 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11260 JY8QFUQ01DLE5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11261 JY8QFUQ01CBHMF productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc 11262 JY8QFUQ01AS1DF No results 11263 JY8QFUQ01DVZXG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1067 99.08 216/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDSVTMIVVEYYFDYW in-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattcggtcactatgatagtagtggaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggagcacagcggccctggggctgcctggctcaaggcactacttccccggaaccggtgacggtgtcgtggaactca 11264 JY8QFUQ01CTRR8 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11265 JY8QFUQ01B9TMB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11266 JY8QFUQ01CPWPG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11267 JY8QFUQ01DM0K4 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 11268 JY8QFUQ01B1WRM unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [2.17.38.11] CARIWDSWSGAF*CV# out-of-frame - stop codons Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttttgatgtgtgggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11269 JY8QFUQ01BWXHB unproductive Homsap IGHV4-39*07 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt 9 7 X 9.7.X [1.17.38.11] CARAVLDNAWPIYYDFLG (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01BWXHB ; 10 AA in Homsap_IGHV4-39*07), and low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccatcaccacttggcattactggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgactttttgggggcccaaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11270 JY8QFUQ01B8WV1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11271 JY8QFUQ01CIBLS productive Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 551 71.3 164/230 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [6.17.38.11] CARERDKSGGGAGDFDSW in-frame - Low V-REGION identity (71,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccagtggcattgttaatggcgaaggttttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctagagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctggagttacagtctgtgaccgccgcagacacggccttatatttttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11272 JY8QFUQ01A2R81 No results 11273 JY8QFUQ01AKJNV unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 832 87.5 189/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [2.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11274 JY8QFUQ01CZWU7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11275 JY8QFUQ01BH03V productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cgacgatgggtcctgcagaaAactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 11276 JY8QFUQ01AL1N5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagacccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 11277 JY8QFUQ01BA1SC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11278 JY8QFUQ01AK5UN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 893 89.59 198/221 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) aggcctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11279 JY8QFUQ01B5XW8 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDRGKIAAIALDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); tggatacaAattttatcgactattatatagaatgggtgcgacaggcccctggacaaagacctgagtggatgggaataatcagccctagaggaaggagcccaacttacgcacagaacttccagggcagagtcactatgaccggcgacacgtccacgagcacagtctacatggaattgagtgatttgagatctgacgacacggccgtgtattattgtgcgagagatcggggcaaaatagccgcaatcgccttggacgtctggggccaagggaccacggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11280 JY8QFUQ01A6KC0 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11281 JY8QFUQ01A91ZM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); cctctggattcagatttagcagctatgccaGtgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11282 JY8QFUQ01CDH4K No results 11283 JY8QFUQ01CJJXA productive (see comment) Homsap IGHV3-33*03 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.37.11] CARAASHGWYLDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) gtctggattcatcttcagtggctatggcatgcactgggtccgccaggtcccaggcaagggccCtggagtgggtggcggttattcggtatgatggaactaatgatgactatgcagactccgtgaagggccgattcaccatctccaaagacacctccaagaacactctctatctgcaaatgaacagcctgaggccgaggacacggctatatattattgtgcgagagcggctagccatgggtggtacctggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11284 JY8QFUQ01CRC4Q productive Homsap IGHV3-21*04 F 975 95.33 204/214 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [0.17.38.11] CARAVSNQVDVW in-frame + tggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11285 JY8QFUQ01ALN5G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11286 JY8QFUQ01AVB9Z No results 11287 JY8QFUQ01DHO9S productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11288 JY8QFUQ01BV4T8 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 11289 JY8QFUQ01DQYS5 productive (see comment) Homsap IGHV3-11*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaaggaactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11290 JY8QFUQ01CA390 No results 11291 JY8QFUQ01CWX55 productive Homsap IGHV3-7*01 F 904 91.2 197/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + tctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11292 JY8QFUQ01BPSCI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKRLQAVADDAFDFW in-frame + cctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgaacagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11293 JY8QFUQ01B9L2E unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11294 JY8QFUQ01CELAQ productive Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 502 68.83 159/231 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [7.17.38.11] CARERDKSGGGAGDFDSW in-frame - Low V-REGION identity (68,83% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccagtggcattattaatagcgaaggattttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctggagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctgaagttacagtctgtgaccgccgcagacacggccgtatatttttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11295 JY8QFUQ01AEJQ0 productive Homsap IGHV1-2*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARDGRGFSYGENLDHW in-frame + tggatacagcttttccggctactatatacactgggtgcggcgggcccctggacaagggcttgagtggatgggatggatcaaccctaacagtggtggcccagaatatgcacagaaatttcagggcagggtcaccatgaccagagacacgtccaccaccacagcctacatggaaataatcaggttgacatctgacgacacggccgtctattactgtgcgagagatggccgtggattcagttatggtgagaaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtcagggcttcttccccc 11296 JY8QFUQ01CC0ZG unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CASFRVLESGY## out-of-frame + tctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11297 JY8QFUQ01CF5AI productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1007 94.64 212/224 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD6-19*01 F 3 8 10 11 8.10.11 [1.17.38.11] CTTDIVSQWPVRW in-frame + cctctggactcagtttcactaacgcctggatgagctgggtccgccaggctccggggaaggggctggagtgggttggccggattaaaagcaaaactgatggtgggacaacagagcacgctgcacccgtgaaaggcagattcaccatctcaagagatgactcaaaaaacacgctgtatctgcaaatgaacagcctgaaaaccgaagacacaggcgtttattattgtaccacagatattgtctcccagtggccggtgcgctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11298 JY8QFUQ01AHGN8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggaccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc 11299 JY8QFUQ01A5DW7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11300 JY8QFUQ01CRGV4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11301 JY8QFUQ01AW1SP productive Homsap IGHV3-48*03 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARESWWSGFYGWYDPW in-frame - gcctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11302 JY8QFUQ01CNY5Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11303 JY8QFUQ01BCWQ9 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); agtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11304 JY8QFUQ01BB1MS No results 11305 JY8QFUQ01BYIEM productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMFYYGMDAW in-frame - cctctggatttaccttcagttcttatagtgtcaactgggtccgccaggctccagggaagggcctggagtgggtctcatatattgataatagtggttctaccatatattatgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggccgtttattactgtgcgaaagatcggacactacacacacccgctcagatgttttattatggtatggacgcctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11306 JY8QFUQ01AOS3H No results 11307 JY8QFUQ01ADJ6A productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 723 82.24 176/214 nt 81.78 175/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'T' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatcTattccctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagagcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11308 JY8QFUQ01CNFA2 No results 11309 JY8QFUQ01BRW0B productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 860 88.53 193/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + cctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11310 JY8QFUQ01DFGEE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 214 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11311 JY8QFUQ01ASDGB productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 856 88.13 193/219 nt 87.21 191/219 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [2.17.37.11] CVSDRELHYQHLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) agcgtctggattcaacttcaatagttTttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11312 JY8QFUQ01CR9KI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggcccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcaccctagccagatgggaacgtggtcatcgcctgcctggtccagggtcttcttccccca 11313 JY8QFUQ01CK7SR productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11314 JY8QFUQ01B7VBT productive (see comment) Homsap IGHV4-61*02 F 890 90.7 195/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [2.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 219 to 219 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctccggtggctccatcagtaCTGGTTattactactggGagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaaAcccctccctccCagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11315 JY8QFUQ01BP74B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccaatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactcag 11316 JY8QFUQ01BPU8S productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + cctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11317 JY8QFUQ01AY1CD unproductive Homsap IGHV3-9*02 F 901 90.41 198/219 nt Homsap IGHJ2*01 F 85 62.26 33/53 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CGKDMRPGGMD#LG out-of-frame - gcctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctgggggccagggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11318 JY8QFUQ01CHTKO unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRGLY*WCMLCR#DFW out-of-frame + stop codons cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggcttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11319 JY8QFUQ01CBZC1 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 817 85.14 189/222 nt 84.68 188/222 nt 8 10 X 8.10.X [1.17.37.X] null + No rearrangement found in FR3-IMGT, from codon 94 of V-REGION: 2 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag 11320 JY8QFUQ01CQKGX unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 84 51.52 68/132 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagtacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11321 JY8QFUQ01BM2JY productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 11322 JY8QFUQ01C6LCV unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 14 8.8.14 [1.17.38.11] CARGL*ER*WWSLPQE (see Functionality comment) in-frame - stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION catctggactcaccttaagtacttatgacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctggtctgattgaagtaataaatattatgcagactccgtgaagggccgattcaccatctccagagacaaatccaagaacacgctgtatttgcatatgaacagcctgacagccgaggacaggactgtgtctgactgtgcgagaggcctgtaggaacgataatggtggtcactaccccaggaaagccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11323 JY8QFUQ01DKS16 productive (see comment) Homsap IGHV4-59*03 F 844 88.73 189/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.16.38.11] CARGRTVVTVIDYMDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctggtggActccattagcggttactattggacctggatccggaaaccccaggaaagggactgagtggattggaaatatccactacagtgggagcaccaagtacagtccctccctcaagagtcgagtcaccatatcactcgccacgtccaagaatcaattcgccctgaagttgacctctgtgaccgctgcggacacggccgtctattattgtgcgagaggacgaacggtggtgactgttattgactacatggactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11324 JY8QFUQ01BVZ1U unproductive Homsap IGHV4-61*02 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 10 7 X 10.7.X [1.17.38.11] CAREKGSDPS#NWFDPW out-of-frame + in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgGggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaaaggtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 11325 JY8QFUQ01DLSH2 No results 11326 JY8QFUQ01A13KG unproductive Homsap IGHV3-48*03 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD1-1*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGSLGSG#DHW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggGggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgaacagcctgagagccgaggacacggccgtattttactgtgcgaggggctcgctcggttcgggtgggaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 11327 JY8QFUQ01B624X No results 11328 JY8QFUQ01BNE9H unproductive Homsap IGHV3-66*02 F 881 90.23 194/215 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAALHDPPWGWLD#PG out-of-frame + cctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11329 JY8QFUQ01BIB1C No results 11330 JY8QFUQ01CT766 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaagactacttcccccgaaccggtgacggtgtcgtggaactcag 11331 JY8QFUQ01BUIPP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 98.62 214/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'CA' (2 nucleotides at position 82 to 83 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaagGgggctggagtgggtctcatccCAattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11332 JY8QFUQ01AXFX6 productive Homsap IGHV3-64*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11333 JY8QFUQ01B7KJV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDTRMAAAGSGFDCW in-frame + ctctggattcacctttagtcgctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctctacttttggtattagtgagggtgacacatactacgccgactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccacatactactgtgcgagagacactcgtatggcagctgctggttcagggtttgactgctggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11334 JY8QFUQ01DMW84 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + gtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11335 JY8QFUQ01DV2TG unproductive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARETLPLGVGG#LDNW out-of-frame + stop codons ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggtttttagacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 11336 JY8QFUQ01CSHGI productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11337 JY8QFUQ01CQZTC productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11338 JY8QFUQ01CHVJ1 productive (see comment) Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11339 JY8QFUQ01DERJL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11340 JY8QFUQ01DU6KV unproductive Homsap IGHV3-9*01 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CVKDRKAGGYNLLDAFDI## out-of-frame - in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagAttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccagggaacccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11341 JY8QFUQ01A75KS No results 11342 JY8QFUQ01B5RK2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 98 52.63 70/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11343 JY8QFUQ01CSZGR unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11344 JY8QFUQ01DEUP9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 651 99.25 132/133 nt 98.5 131/133 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD2-2*03 F 2 8 X X 8.X.X [1.11.24.11] CAKFMGVVVVPAAHNWF#PL out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 50 of V-REGION: 84 nucleotides (from position 62 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagcagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11345 JY8QFUQ01BQOBI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11346 JY8QFUQ01DTPOY unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 11347 JY8QFUQ01DGJE0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11348 JY8QFUQ01CEOFM No results 11349 JY8QFUQ01CWOYG productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaaggggctggagtgggttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11350 JY8QFUQ01CTDFC unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 97 52.14 73/140 nt 10 9 X 10.9.X [1.17.9.X] null - No rearrangement found stop codons tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11351 JY8QFUQ01CSVFI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-NL1*01 F 844 88.73 189/213 nt 88.26 188/213 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11352 JY8QFUQ01BRGH5 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 868 89.35 193/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - tctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11353 JY8QFUQ01BP7RX productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11354 JY8QFUQ01C1094 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11355 JY8QFUQ01AS600 productive (see comment) Homsap IGHV3-48*01 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tccggattcaGatttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga 11356 JY8QFUQ01ACLAL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11357 JY8QFUQ01DB8G8 No results 11358 JY8QFUQ01DA3VW unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFLDY## out-of-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggctgtcgtggaactc 11359 JY8QFUQ01BZFMX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 824 86.7 189/218 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAAVGVGSAVSFQYW in-frame - cctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11360 JY8QFUQ01DL31Y unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1012 96.76 209/216 nt 95.37 206/216 nt 7 8 X 7.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) ctctggattcaGccttcagtagtataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaaggGgccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggaggggggcgagccgcttgaccactgggggccagggaacccctggtcagcgtctccctctgcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11361 JY8QFUQ01C66OW productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11362 JY8QFUQ01A2OGP unknown (see comment) Homsap IGHV1-3*01 F, or Homsap IGHV1-3*02 F (see comment) 270 64.05 98/153 nt 8 8 X 8.8.X [0.17.17.X] null + No rearrangement found Low V-REGION identity (64,05% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcaccttcactgactatgctatgcattgggtgcgccaggcccccggacaagggcttgagtggatgggatggatcaacgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11363 JY8QFUQ01BYFKL No results 11364 JY8QFUQ01DS6VV productive (see comment) Homsap IGHV1-3*01 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CVRGRSPPGDWFDPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); tggatacaccttcactaAtttatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctgggggccagggaaccctgtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11365 JY8QFUQ01AJ9AF No results 11366 JY8QFUQ01C1CFQ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gtctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcagtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11367 JY8QFUQ01DRRGP productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag 11368 JY8QFUQ01CBP62 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11369 JY8QFUQ01C7P5K productive (see comment) Homsap IGHV3-7*01 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDDDFWNGKHFDPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift) ctctggattcagtcttaataactactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagagacgacgatttttggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11370 JY8QFUQ01C73KI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CAKDMGGDYYIFHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); gcttctggattctcctttagcaacnatgccctgggcCtgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11371 JY8QFUQ01AT23W unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREGGGAVRRK#YFDYW out-of-frame + ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11372 JY8QFUQ01B9QWJ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 914 91.28 199/218 nt Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDQMSGGMPEA#FDIW out-of-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaatgtctgggggcatgcccgaggcttttcgacatctggggccaagggacaatggtcaccgtctcctcaggccctcaccaaatgggccccaatcggtttccccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaacggtgacggtgtcgtggaactca 11373 JY8QFUQ01CNIRS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11374 JY8QFUQ01B4R6M No results 11375 JY8QFUQ01CCPBN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11376 JY8QFUQ01A5BG8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 938 93.87 199/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 7 8 X 7.8.X [X.17.38.11] CAKLSGGGSTY#FDYW out-of-frame - gattcacctttaacaactatgccatgagctgggtccgccaggctccgggggaggggctggagtggctctcaactgttagtggtcgtggtgacagcacatactacgcagactccgtgcagggccggttcatcatctctagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaactgtcgggcgggggcagcacgtaccctttgactactggggccagggaaccctggtcacagtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11377 JY8QFUQ01BJN3B productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 868 89.35 193/216 nt 88.43 191/216 nt Homsap IGHJ1*01 F 215 90.38 47/52 nt Homsap IGHD5-12*01 F 3 8 7 14 8.7.14 [2.17.38.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); gcctctgacttaaTcggtcagtgacaattacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacggttcccagaacacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtaCtttttgtgcgagtggtggttattcgggctcgggtgaatatttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11378 JY8QFUQ01DWSY6 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaTggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11379 JY8QFUQ01AZHXN No results 11380 JY8QFUQ01CT4CD unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.37.11] FVEKSLL*QFAPAL#DYW out-of-frame - stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) ctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaaccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctaattttttgtcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11381 JY8QFUQ01AKFBE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccag 11382 JY8QFUQ01AN9EC unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 752 83.03 181/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARTPCSGGNCYLRGHDL# out-of-frame - Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcgggtatttattattgtgcgcggacgccttgcagtggtggaaattgttaccttagaggccacgacctctgggccagggaacccaggtctccgtttccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11383 JY8QFUQ01DK6RA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 7 8 X 7.8.X [1.17.38.11] CAKQNIVM#YYFDQW out-of-frame + in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctggattcacgtttaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11384 JY8QFUQ01DPFIO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKGDSGGYTHNYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaAggggctggtgtgggcctcacgtgttaatggtgatAgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11385 JY8QFUQ01B403G unknown (see comment) Homsap IGHV4-59*10 F (see comment) 440 66.98 144/215 nt 66.51 143/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01B403G ; 8 AA in Homsap_IGHV4-59*10), and low V-REGION identity (66,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 63 of V-REGION: 'AGAACAATCTCTTCAATACCTCCCTCAGGAGTC' (33 nucleotides at position 100 to 132 in the user submitted sequence), (do not cause frameshift); ttctggctggcgccatcagcgatattggctccttctggagctgggtccgacagcccgccgggagttcgctggagtacatcggacgtgtctataatagtgAGAACAATCTCTTCAATACCTCCCTCAGGAGTCgaatcaccaactacaatcctgccctaaggagtcgagtcaccatgtcagtggacacgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11386 JY8QFUQ01AG01M productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARALIVVAGAPVYWG in-frame + ctctggattcaccttcagtagttatagtatgatctgggtccgccaggctccagggaaggggctggagtgggtcgcttcaattagtcataccgggggttccaaatattacggagactcactgaagggccgattcgccatctcaagagacaacgacaagaactcactgtatctgcaaatgaccagcctgagagccgaggacacggctgtctactactgtgcgagagccctaatagtagtggctggtgcccctgtctattgggggccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11387 JY8QFUQ01A56OJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11388 JY8QFUQ01CAQG8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctaggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11389 JY8QFUQ01DOY4X No results 11390 JY8QFUQ01A3OUD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 11391 JY8QFUQ01BVTC6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 11392 JY8QFUQ01BC28P productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11393 JY8QFUQ01BK9R4 No results 11394 JY8QFUQ01B5TTD No results 11395 JY8QFUQ01DTFKX No results 11396 JY8QFUQ01BXBPF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + cctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11397 JY8QFUQ01BUHVK No results 11398 JY8QFUQ01CY3RH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11399 JY8QFUQ01BIWOC productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1030 95.56 215/225 nt 95.11 214/225 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 1 10 9 13 10.9.13 [1.17.38.11] CVRDVGWGLDTLDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggggacactgtctctagcaacagtgctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatattacaggtcccagtggtattatgattatgcagtgtctgtgcagagtcgaataaccatcatcccagacacatccaagaaccagttctccctgcagttgaactctgtgattcccgaggacacggctgtgtattactgtgtaagagacgtcggctggggattggatactcttgatatctggggccaagggacaatggtcatcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11400 JY8QFUQ01BEXDZ unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F or Homsap IGHV4-61*01 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 3 8 7 X 8.7.X [1.17.38.11] CAKNLWLRTR#YW out-of-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgaaaaatctctggctacggacaaggctactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11401 JY8QFUQ01CK138 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttggttattatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 11402 JY8QFUQ01AJ1GW No results 11403 JY8QFUQ01AI8GD productive (see comment) Homsap IGHV3-7*01 F 1009 95.89 210/219 nt 95.43 209/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11404 JY8QFUQ01BDI1Z productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARVDFYGSSKYKGFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcgatcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11405 JY8QFUQ01AZUUS productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11406 JY8QFUQ01AC0DA productive Homsap IGHV3-48*01 F 980 95.35 205/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARERGNSYGEIDYW in-frame - ctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaagactacttccccgaaccggtgacggtgtcgtggaactcag 11407 JY8QFUQ01C6P75 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 X 7.8.X [1.17.38.11] CARDMGSGRYLNL#DYW out-of-frame - in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ggtctggattcatcttcttgaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatatttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11408 JY8QFUQ01BQ2SE No results 11409 JY8QFUQ01AORVQ No results 11410 JY8QFUQ01BHBH9 unproductive Homsap IGHV4-4*07 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 3 8 7 X 8.7.X [1.17.38.11] CARSGWDNQ#DFW out-of-frame + in CDR1-IMGT at codon 37 of V-REGION: 'GCACTT' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctggtgtcgccaccagtagtgGCACTTactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccCcctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaattgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11411 JY8QFUQ01C0QXR No results 11412 JY8QFUQ01AESJ4 unknown (see comment) Homsap IGHV3-7*02 F 118 60.24 50/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11413 JY8QFUQ01AJ7GQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcacgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg 11414 JY8QFUQ01CQ1NV unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 660 78.97 169/214 nt 78.5 168/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [0.17.38.11] CARERRPGGYPNGYHHFYGMDV## out-of-frame + Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggGcaattatttcatatgatggaaataggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgtcgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacatatttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11415 JY8QFUQ01AX4LK No results 11416 JY8QFUQ01CQ37A productive (see comment) Homsap IGHV2-5*02 F 1021 91.36 222/243 nt 90.12 219/243 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 18 10.7.18 [9.17.38.11] CAHNSLYDRNGYYLTYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 152 to 152 in the user submitted sequence), (cause frameshift); accctcacactgacctgcaacctctctGggggtctcactcagcagtcgtggagtgggtgtgggctggatccgtcaggccccaggAaaaggccctggagtggcttgccctcattgattgggatgatgacaagcgctatagtccatctctaaaCggggaggctcaccatcaccagggacacctccacaggccaggtggtcctcacaatgaccaacatgcaccctgtggacacagccacatattactgtgcacacaacagtctctatgataggaatggctattatttgacgtactttgatcactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11417 JY8QFUQ01B4BNR No results 11418 JY8QFUQ01B59I4 No results 11419 JY8QFUQ01CQS64 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11420 JY8QFUQ01AOCOZ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gtctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 11421 JY8QFUQ01DTVBR No results 11422 JY8QFUQ01DO95W No results 11423 JY8QFUQ01A1C30 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREVKYGDDTGG#WFDPW out-of-frame + gtctggattcaccttcagtgactctggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatggtatgatggatattataaacaacatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattactgtgcgagagaggtgaaatacggtgacgacacgggggggatggttcgacccctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttcccccag 11424 JY8QFUQ01BB8AU productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11425 JY8QFUQ01A9H3D unknown (see comment) Homsap IGHV3-13*01 F (see comment) 361 67.63 117/173 nt 8 7 X 8.7.X [1.17.24.X] null - No rearrangement found stop codons Low V-REGION identity (67,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11426 JY8QFUQ01CS771 productive (see comment) Homsap IGHV4-61*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 1 8 7 13 8.7.13 [2.16.38.11] CASVRPSGERFFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 37 of V-REGION: 8 nucleotides (from position 31 in the user submitted sequence), (cause frameshift) gtctctggtggctcgctcacgggttcaagtgggctggatccggcagcccccaggggagggactgcaatggattggacatatctctttcgttggggacaccagttatgacccttccctcaggagtcgagtcaccatttcagtcgacacgtccaagaaccagttctccctgaaactgaactctatgactcctgcggacacggccgtctattactgtgcgagcgtgcgtccttcgggagaacggttcttcgacttctggggcctgggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11427 JY8QFUQ01BP1DC unproductive Homsap IGHV3-48*02 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaGggggctggagtgggAtttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11428 JY8QFUQ01DHNAH productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11429 JY8QFUQ01AQ0RE productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11430 JY8QFUQ01BKBKE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 136 76.6 36/47 nt Homsap IGHD2-15*01 F 1 8 8 6 8.8.6 [1.17.38.11] CASLPLVW in-frame - ttttaattacaacgttaccacctactggatgggctgggtgcgccagaagcccggaaaaggcctggagtcgatgggaatcatctatcctggtgactccgatgtcaggtacagtccgccctttcaaggccaggtcaccatgtccgtcgacacgtccaccaatgtcgcctacctgcagtggaacagcctgaaggcctcggacaccgccatgtattattgtgcgagtctcccccttgtctggggccaggggacaatggtcaccgtcgcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11431 JY8QFUQ01AEPDX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11432 JY8QFUQ01AZ3LY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11433 JY8QFUQ01ATPQS productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11434 JY8QFUQ01CQ508 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11435 JY8QFUQ01C2PD8 No results 11436 JY8QFUQ01BDHZ7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaac 11437 JY8QFUQ01AWF3H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 11438 JY8QFUQ01A2TQ5 No results 11439 JY8QFUQ01CEBF1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11440 JY8QFUQ01DQQIL No results 11441 JY8QFUQ01C2J6R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggCtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11442 JY8QFUQ01C4B5M No results 11443 JY8QFUQ01ATW8E unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARERGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11444 JY8QFUQ01CZOCG unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCG#FDYW out-of-frame + stop codons ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagaacacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11445 JY8QFUQ01DK4P3 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1020 97.66 209/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11446 JY8QFUQ01CTMRO unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGH## out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgTtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11447 JY8QFUQ01C0NG5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc 11448 JY8QFUQ01DKKI3 No results 11449 JY8QFUQ01AUE9D productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); cctctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11450 JY8QFUQ01AAW35 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 914 91.28 199/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11451 JY8QFUQ01AMSPO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11452 JY8QFUQ01CXZV1 No results 11453 JY8QFUQ01A7XDX productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11454 JY8QFUQ01BZLHT unproductive Homsap IGHV3-48*01 F 945 93.09 202/217 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFEPYDY# out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactgggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11455 JY8QFUQ01B252D productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 800 86.05 185/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARLAMLRGVPTWFDPW in-frame - cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactcagtgaagggccgattcaccatctccaaagacaacgccaaaaacttattgtttttgcaaatggacagcctgagagacgaggacacggctatttattactgtgcgagacttgcaatgcttcggggagtccccacctggttcgacccctggggccagggagccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11456 JY8QFUQ01B6832 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.37.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 11457 JY8QFUQ01B996S No results 11458 JY8QFUQ01AZZ4J No results 11459 JY8QFUQ01ARI4W productive Homsap IGHV4-39*03 F 919 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11460 JY8QFUQ01BYVHP No results 11461 JY8QFUQ01CMEMC productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ggcctctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11462 JY8QFUQ01BU88H productive (see comment) Homsap IGHV3-48*02 F (see comment) 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [2.17.38.11] FVTERGGGLLRYLDLW in-frame - Potentially, because of detected insertion/deletion Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccagggaaggGggctggagtggatttcatatattagtagcagtagtcaaacgatttactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactttgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11463 JY8QFUQ01DF59O No results 11464 JY8QFUQ01DM3BG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11465 JY8QFUQ01DM1S8 productive (see comment) Homsap IGHV4-59*03 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.37.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) gtctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccCaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11466 JY8QFUQ01CHP9C No results 11467 JY8QFUQ01CHIXP No results 11468 JY8QFUQ01B5DKA No results 11469 JY8QFUQ01CULC9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 412 88.46 92/104 nt 87.5 91/104 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 11470 JY8QFUQ01COX54 No results 11471 JY8QFUQ01BRZGC No results 11472 JY8QFUQ01AUPN6 productive (see comment) Homsap IGHV4-59*03 F 1025 97.67 210/215 nt 96.74 208/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARGLRWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaatCagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatgcctattacagtgggagcaccaactacaAacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccaattctccctgaagctgacctctgtgaccgctgcggacacggccgtctattactgtgcgagagggttgcgttggaacgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11473 JY8QFUQ01AZGCF No results 11474 JY8QFUQ01DB35I unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.25 185/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDNVTF#DAFDIW out-of-frame - gtctgggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatttggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcaccctatatttacaaatgaatagcctgagagtcgaggacacggctgtgtattactgcgcgagagataatgtcacctttgggatgcctttgatatttggggccgggggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11475 JY8QFUQ01ATN66 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.16.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'A' (1 nucleotides at position 208 to 208 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccaggaaggggctggagtgggtctcaggtattagtggtagtggtgAaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccAgtttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11476 JY8QFUQ01ANTFH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11477 JY8QFUQ01ADPMB No results 11478 JY8QFUQ01AQ0K4 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 17 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctctggattcaccCTttgggttattatggcatggactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11479 JY8QFUQ01CRDUG No results 11480 JY8QFUQ01CE4MI productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD6-6*01 F 2 8 10 16 8.10.16 [1.17.38.11] CTRRSIADNFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tctgggttcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagcaaagctaacagttacgcgacagcatatgctgcgtcggtgAaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtactagacggagtatagcagataacttctactactacggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11481 JY8QFUQ01DDE64 productive Homsap IGHV3-21*04 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11482 JY8QFUQ01BXFLK unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11483 JY8QFUQ01CV33N No results 11484 JY8QFUQ01AVMKB productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11485 JY8QFUQ01CE7YT productive Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CGRIAKPGLGALDLW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11486 JY8QFUQ01DOIZU productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1002 96.73 207/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARTTSSSGWYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ctctggaggctCccattagtaattactacCtggagttgGgatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaatcagttcttcctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgaggactacttctagtagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11487 JY8QFUQ01DJQ5C productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 841 89.86 186/207 nt 89.37 185/207 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 8 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctctggtgactccccacttctggagctggatccggcagcccccgggaaagggcctggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccag 11488 JY8QFUQ01AL2FG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11489 JY8QFUQ01BX5EO unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CATLRGGY#FDYW out-of-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggctactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttcccccgaacccggctggacggtgtcgtggaactcag 11490 JY8QFUQ01BMIPQ unproductive Homsap IGHV4-61*02 F (see comment) 560 72.85 161/221 nt 72.4 160/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CARECSNSKVGPRALDS## out-of-frame + Low V-REGION identity (72,85% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'CGG' (3 nucleotides at position 60 to 62 in the user submitted sequence), (do not cause frameshift); tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagccccgcCGGggaaggggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctatatttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattcctggggccccgggaagtctggtcaccgtatcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11491 JY8QFUQ01CGGNW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11492 JY8QFUQ01BK1LC No results 11493 JY8QFUQ01BFVM4 productive Homsap IGHV3-30*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacccgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactactttcccgaaccggtgacggtgtcgtggaactc 11494 JY8QFUQ01DIAT7 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 1 8 8 19 8.8.19 [1.17.38.11] CARKWPPEEMAPLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaatggcccccagaagagatggctcccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgcacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11495 JY8QFUQ01CUR2C productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11496 JY8QFUQ01AP3IL No results 11497 JY8QFUQ01AWNB8 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11498 JY8QFUQ01CWCXK unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 11499 JY8QFUQ01CKOQL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11500 JY8QFUQ01B8FNM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11501 JY8QFUQ01DJM48 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11502 JY8QFUQ01BAFIL No results 11503 JY8QFUQ01CHNO7 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc 11504 JY8QFUQ01A9N1H No results 11505 JY8QFUQ01AVKBO No results 11506 JY8QFUQ01DQ94B productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11507 JY8QFUQ01BBMAT No results 11508 JY8QFUQ01A29HR productive (see comment) Homsap IGHV3-11*01 F 828 87.1 189/217 nt 86.18 187/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaaAggactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtgGgtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctggcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 11509 JY8QFUQ01DMVW5 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11510 JY8QFUQ01CGMRL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccacaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 11511 JY8QFUQ01BERLC unproductive Homsap IGHV3-11*01 F 878 88.99 194/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARGPHSYASDGHNFDF## out-of-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagcttcagtgactattacatgggttggatccgccaggctccagggaaggggctggagtggcttgcatatattactagtaccagtgccaccatatattatgcagactctgtgaggggccgattcaccacctccagggacaacgccaaaaactcactgtatctgcacataaacagcctgagagtcgaggacacggccgtttattactgcgcgagaggtccccattcctatgccagtgatggtcacaattttgacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11512 JY8QFUQ01BJM8B unknown (see comment) Homsap IGHV1-2*02 F 503 86.47 115/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc 11513 JY8QFUQ01DRXN2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARDILGATRFDYW in-frame - cctctggattcaccttcagcagctatgccatgagctgggtccgccaggctccagggaagggcctggagtgggtctcagctattagtggtattggtgggagtacattctacgcagactccgtgaagggccggttcaccatcaccagagacaattccaacaacacgctgtttctgcaaatgaatagcctgagagccgaggacacggccatatattactgtgcgagagatattctgggagctactcggtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11514 JY8QFUQ01CMSTH productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgtgtctgtggaactcag 11515 JY8QFUQ01B821R productive Homsap IGHV1-2*02 F 817 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame - tggatatactttcaccgaccattatgtttactggatgcgacaggcccctgganaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11516 JY8QFUQ01DLTIC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGYYPQVA#FDYW out-of-frame - ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagcggtagtggtgatagcacatactacgcagactccctgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgggagccgaagacacggccgtatatcgctgtgcaggctattatccccaagtagcccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11517 JY8QFUQ01CYWC2 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDRNYAFDYW in-frame + ctctggattcaccttcagcagctttagtatgaactgggtccgccaggctccagggaagggactggagtggctttcatacattagtaatactggtagtaacaaatactacgcagactctgtgaagggccgattcaccatctccagagacgatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgtgcgagagatcggaactacgctttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11518 JY8QFUQ01BT51R unproductive (see comment) Homsap IGHV3-9*01 F 1072 99.09 217/219 nt 98.63 216/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKRLFRHIWKF#FDGW out-of-frame - stop codons in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcacctttggtgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagcataggctatgcggactctgtgAaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagacctgaggacacggccttgtattactgtgcaaaaagactattcagacatatatggaaatttctttgacggctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11519 JY8QFUQ01C0U09 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11520 JY8QFUQ01A8IYT productive (see comment) Homsap IGHV3-30*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11521 JY8QFUQ01A3UDN unproductive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt Homsap IGHJ1*01 F 107 67.31 35/52 nt Homsap IGHD1-26*01 F 2 8 10 X 8.10.X [2.17.38.11] CLRPPRYDPW# out-of-frame - gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctgggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11522 JY8QFUQ01A03N6 productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11523 JY8QFUQ01AJZDU productive Homsap IGHV3-66*02 F (see comment) 760 83.8 181/216 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [2.17.38.11] CARHLMVYALDVW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11524 JY8QFUQ01BV54S productive Homsap IGHV3-48*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11525 JY8QFUQ01B8I89 productive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame - cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11526 JY8QFUQ01BKOVT productive (see comment) Homsap IGHV3-9*01 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggatttaactttgatcaatatgccatgtattGgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctgggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11527 JY8QFUQ01BPTTW No results 11528 JY8QFUQ01AMAAI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11529 JY8QFUQ01CJGIP unproductive Homsap IGHV3-7*02 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSAYFSTGY# out-of-frame - in FR2-IMGT at codon 42 of V-REGION: 'TCC' (3 nucleotides at position 39 to 41 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); tctagattcacctttaggacatattggatgaggttgggTCCcgcccaagctccagggaaaggGGgctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgagcagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactgggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11530 JY8QFUQ01BJ4OQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11531 JY8QFUQ01CG70I unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 106 53.44 70/131 nt 8 8 X 8.8.X [1.17.9.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 11532 JY8QFUQ01B8WTX unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11533 JY8QFUQ01BS4WZ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [2.17.38.11] CARDNYGDYW# out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'TG' (2 nucleotides at position 94 to 95 in the user submitted sequence), (cause frameshift); ctctggagttcagccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTGgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcacagtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11534 JY8QFUQ01C0PY0 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11535 JY8QFUQ01ALIUD productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11536 JY8QFUQ01CT8AA productive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggcttcaccttcagtgactactacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtcagggcttcttccccc 11537 JY8QFUQ01AT0ML productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11538 JY8QFUQ01BM58O productive Homsap IGHV3-11*01 F 882 89.86 195/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + ctctggattcatcttcagtgaccactacatgagctgggtccgccaggctccggggaagggtctggagtggatctcatacatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggtgattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11539 JY8QFUQ01DSGY2 No results 11540 JY8QFUQ01AKSD0 No results 11541 JY8QFUQ01A1UEF unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*01 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY#W out-of-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactacctgggggccaggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11542 JY8QFUQ01APSLB productive (see comment) Homsap IGHV3-48*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.16.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11543 JY8QFUQ01A3WOY No results 11544 JY8QFUQ01BUP6V unproductive Homsap IGHV3-74*03 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVDSDGWHGTIDR## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaAaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctgggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11545 JY8QFUQ01ALK8F productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggCaaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 11546 JY8QFUQ01BWQZE No results 11547 JY8QFUQ01APY1W No results 11548 JY8QFUQ01C7D8J productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 957 94.39 202/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctatggtgggtccttcagtggttacacctggaactggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccc 11549 JY8QFUQ01ALCY5 No results 11550 JY8QFUQ01B1XJ2 unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 981 94.93 206/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRDRYTDSWFNGNWF#PL out-of-frame + ctctggattcacatttgatgaatatggcatgagctgggtccgccaatctccagggaagaggctggagtgggtctctggtattaattggaatggtgccagcataggttatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtttctgcaaatgaacagtctgagagccgaagacacggccttgtactactgtgtgagagacaggtataccgacagttggtttaatggaaactggttcgccccctgggccagggaacccaagtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 11551 JY8QFUQ01AY1B0 No results 11552 JY8QFUQ01AD6VN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11553 JY8QFUQ01CBR14 productive Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 863 89.3 192/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11554 JY8QFUQ01BGVCA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11555 JY8QFUQ01CUNMM No results 11556 JY8QFUQ01DRT0U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagtacctataacatgaactgGggtccgccaggctccagGggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11557 JY8QFUQ01DGWHK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11558 JY8QFUQ01CO9R6 productive Homsap IGHV3-11*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [2.17.38.11] CARVKYSSSWSSILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctagagtgggtttcattcattagtagtcctggtatcaggagtttctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccca 11559 JY8QFUQ01BY0OQ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 250 58.76 114/194 nt 58.25 113/194 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (58,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaCcctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11560 JY8QFUQ01CQ4VD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame - cgtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11561 JY8QFUQ01A24RC productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11562 JY8QFUQ01CRIVN unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt 94.12 208/221 nt 10 7 X 10.7.X [2.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagcagtagttcttactactgggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactgggccagcggggaaacccctggtcaccgtctccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccacc 11563 JY8QFUQ01APVPR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11564 JY8QFUQ01DEUV1 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11565 JY8QFUQ01BZJ86 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 856 88.13 193/219 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11566 JY8QFUQ01BXHDN unproductive (see comment) Homsap IGHV3-7*01 F (see comment) 409 65.28 141/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.17.38.6] NR*R in-frame + stop codons Low V-REGION identity (65,28% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaagcgtactatgcggactctgtgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11567 JY8QFUQ01CVP8B productive (see comment) Homsap IGHV4-61*02 F 970 93.24 207/222 nt 92.34 205/222 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [2.16.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) tgtctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactgagtggattgggcgtatatatagcagtgggagcGatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11568 JY8QFUQ01BSWUK unproductive (see comment) Homsap IGHV4-39*02 F (see comment) 762 83.18 183/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CATIVPLFCDSTY*RSRKV#YFDHW out-of-frame - stop codons Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtgcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11569 JY8QFUQ01B5PZ4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11570 JY8QFUQ01B7WY5 No results 11571 JY8QFUQ01CZX79 unproductive Homsap IGHV3-48*02 F 828 87.1 189/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGDTVML#GMDVW out-of-frame + ctccggattcacctccatctcctatggcatgcactgggtccgccagattccaggaaaggggctggagtcggttgcatacattagtgatagtaatagcagcatatactatgcagactctgtgaagggccgattcaccatctcccgagacaaagacaagaagtcagtatatctgcaaatgagcagcctgagagacgaggacacggctatttattactgtgcgaggggcgatacagttatgctcacggaatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11572 JY8QFUQ01DS9QD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-14*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CTKDYPDGRLLNHVFLFDH#W out-of-frame + ctctggattcacgtttgacgactatgccatgagttgggtccgccaggctccagggaaggggccggagtgggtctcaggtattattcctaatagtcgtgacagacactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagagcacagtgtatctgcaaatgaacaacctcagaggcgaggacacggccgtatattactgtacgaaagactatccggacggccgcctgctaaatcacgtcttcctttttgatcacttggggcgagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgtaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 11573 JY8QFUQ01BZEWU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11574 JY8QFUQ01BC7DJ productive Homsap IGHV1-18*01 F (see comment) 719 81.86 176/215 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD1-14*01 ORF 2 8 8 14 8.8.14 [0.17.38.11] CAREPEPRGAYGMDVW in-frame + Low V-REGION identity (81,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggttacgacttttccgcctatagtctcaattggatacgtcaggcccctggacacgggcttgagtgggtgggatggatcagtcgttctggtctccatatattctatgaacagagttttcagggcagagtcaccctgaccacagacacatccacgagcacagcctacatggagctgaggagcctgcaatctgacgacacggccatatattactgtgcgcgagaaccggagccccgaggggcctacggtatggacgtctggggcctagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11575 JY8QFUQ01B7JLL No results 11576 JY8QFUQ01A1WCP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccagGgggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11577 JY8QFUQ01C1OW3 unproductive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11578 JY8QFUQ01CB60R productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc 11579 JY8QFUQ01C37BK unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD2-15*01 F 3 7 8 X 7.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctccggattcaccttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctctcagatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11580 JY8QFUQ01DNLB6 unproductive (see comment) Homsap IGHV4-55*07 P (see comment) 689 79.72 173/217 nt 78.34 170/217 nt Homsap IGHJ6*04 F 90 60.32 38/63 nt Homsap IGHD3-3*02 F 1 9 7 X 9.7.X [1.17.38.11] CARHVRGILQEGHFCSASACHSFDSW# out-of-frame - however the closest V is a pseudogene Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 42 of V-REGION: 'GGGAT' (5 nucleotides at position 44 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CT' (2 nucleotides at position 81 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); tgtctggtgactccatctccagggattatgcgttactgggggtGGGATccgccagtccccagggaagggactggagtggaCTttgggggcgtctctcatgatgggatcaccttctacaccccgtccctcaCgggggcgagtcaccatctccgtggacgggtccaagaaccacttctccctgaggctggactccacgaccgccgcagacacggctatttattactgtgcgagacatgtccgtgggattcttcaggagggacatttctgtagtgcttctgcttgccactccttcgactcctgggggccagggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11581 JY8QFUQ01C4V7J No results 11582 JY8QFUQ01BC8PD productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11583 JY8QFUQ01ABFPI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11584 JY8QFUQ01BEU2A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagatacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 11585 JY8QFUQ01A6DLE productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame - tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11586 JY8QFUQ01ADGIJ No results 11587 JY8QFUQ01CI99L unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDG#YW out-of-frame - ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11588 JY8QFUQ01CJG1W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGLGAYYIYYFDSW in-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggccggagtggctcgcaactatcagtggtagtggaagtaggtcattctacgcagactccctcaggggccgtttcaccatctccagagacaattccaagggcacggtgtacctggacatgaccaccctgggagccgacgactcggccgtgtattactgtgccagagatggagtccgtggccttggtgcttattatatctactattttgactcatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcc 11589 JY8QFUQ01C91CR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctcaggattcaccttcagtaggtactggatgcactGgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11590 JY8QFUQ01BGO73 No results 11591 JY8QFUQ01AXVIZ unknown (see comment) Homsap IGHV3-74*03 F 135 55.56 75/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11592 JY8QFUQ01BWOJ4 No results 11593 JY8QFUQ01DHLHH No results 11594 JY8QFUQ01B639Y productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [X.17.38.11] CTKCSVTIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ggattcaccAtttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgAaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11595 JY8QFUQ01AJVHR productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11596 JY8QFUQ01BG2KZ productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + cctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgctggtcccaggggcttcttccccc 11597 JY8QFUQ01DWQZH No results 11598 JY8QFUQ01CMLMU unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 X 9.7.X [1.17.38.11] CARGETDC##YYFDYW out-of-frame + stop codons tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaactgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11599 JY8QFUQ01A1364 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtatattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11600 JY8QFUQ01BG2XI No results 11601 JY8QFUQ01AX1NQ No results 11602 JY8QFUQ01DITE7 productive (see comment) Homsap IGHV3-48*02 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARADYRNYYAGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctcaggattcaccttcagtacctatagcatgaactgGggtccgccaggctccagGggaaggggctggagtggatttcatacattagcgctactagtactaccatatattacggagactctatgaggggccgattcaccatctccagagacaatgccaagaactcactttatctgcaaatgaatagcctgagagacgacgacacggctgtgtattactgtgcgagagccgactacaggaactactacgccggtatggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 11603 JY8QFUQ01C58E8 No results 11604 JY8QFUQ01C09Y9 No results 11605 JY8QFUQ01DPX57 unproductive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CASRLRSSGGY## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11606 JY8QFUQ01C4N11 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtc 11607 JY8QFUQ01A8WCU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame - cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 11608 JY8QFUQ01CUTH2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11609 JY8QFUQ01BHY5R productive Homsap IGHV3-11*01 F (see comment) 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] YARRRDYGDYGDGFDYW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactatgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcaatgcctggtccagggcttcttccc 11610 JY8QFUQ01DK9JD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaactc 11611 JY8QFUQ01BTDKT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgtctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtctcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11612 JY8QFUQ01DWVME productive (see comment) Homsap IGHV3-21*04 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 7 8 16 7.8.16 [2.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) gcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11613 JY8QFUQ01B7U7C productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11614 JY8QFUQ01AL6EV productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11615 JY8QFUQ01A8RKJ productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) cctctacattcacgtttagtcggtattggatgagctggtccgccaggctccagggaagggcctggagtggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11616 JY8QFUQ01DS6BY No results 11617 JY8QFUQ01ABI4U productive (see comment) Homsap IGHV4-39*03 F 928 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 7 17 9.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11618 JY8QFUQ01C5KM1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11619 JY8QFUQ01CZMGC productive (see comment) Homsap IGHV3-48*01 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11620 JY8QFUQ01A2F1Z unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11621 JY8QFUQ01CNWIQ productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11622 JY8QFUQ01AHX1B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11623 JY8QFUQ01DU62D productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 1016 97.21 209/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARGPGRGYSYGYLYYW in-frame - tctatggtgggtccttcagtggttactactggaactggatccggccagccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcggacacggctgtgtattactgtgcgagaggcccggggcgtggatacagctatggttacttatactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11624 JY8QFUQ01CBX8Y unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11625 JY8QFUQ01BQVJM unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 11626 JY8QFUQ01CX6W8 No results 11627 JY8QFUQ01BTUG9 productive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11628 JY8QFUQ01C6PSP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11629 JY8QFUQ01DNSKU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11630 JY8QFUQ01BW865 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgcttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaagtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11631 JY8QFUQ01B41FE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11632 JY8QFUQ01BEE11 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 898 89.64 199/222 nt 89.19 198/222 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-3*01 F 2 10 7 18 10.7.18 [2.17.38.11] CARSQRSAWSGQPRNWFETW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 31 of V-REGION: 'A' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); tctgctggtggctccatcaAgcagtaacccttattactggggctggatccgccagcccccatggggggggctggagtgggttggcagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgaatcaccatgtccgtggacacgtccaggacccagttctccctgaagttgagctctgtgaccgcctcagatacggctgtgtattattgtgcgaggtcccaaaggagtgcttggagtggacagcctagaaactggttcgagacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11633 JY8QFUQ01AEYTS productive Homsap IGHV3-7*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtctgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11634 JY8QFUQ01BTFS8 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARGDGVKDDY## out-of-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11635 JY8QFUQ01ACKK7 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) cctctggatcaccctttggttattGatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11636 JY8QFUQ01ASCWW No results 11637 JY8QFUQ01AMDQC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cagcctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgAaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11638 JY8QFUQ01CNRIE unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt 91.32 200/219 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.16.38.11] CARPAFSGSGTYRP#DGFDVW out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ggtttctggatacagcCtttaccaattactggatcggctgggtgcgccaggtgcccggaaaagcctggagtggatCggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagctttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11639 JY8QFUQ01ACBLB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKVWIELWSAGDHFDNW in-frame + cctctggattcatatttactagatatgccatgacctgggtccgccaggctccagggaagggtctggagtgggtcgcttctatcagtggtagtgggattagtaaaaagtacgcagacggcgtggagggccgattcaccatctccagagacagttccgagagaacactgtatctacaaatgaacagcctgagagtcgaggacacggccacatattattgtgcgaaagtatggatagagttatggtcggctggggaccactttgacaactggggccagggaaccctggtcaacgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11640 JY8QFUQ01CG8EF No results 11641 JY8QFUQ01CADUW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11642 JY8QFUQ01APLX8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + ctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11643 JY8QFUQ01A6CF8 No results 11644 JY8QFUQ01BBSCF productive (see comment) Homsap IGHV4-61*02 F 897 90.0 198/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11645 JY8QFUQ01CWUX1 unproductive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ5*01 F 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARAVSNQVDV## out-of-frame - ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctgggggccaagggaccacggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11646 JY8QFUQ01DGWJE No results 11647 JY8QFUQ01DBVMQ productive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ4*01 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 3 10 7 11 10.7.11 [1.17.37.11] CARAREFLTFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaacaatgatactttctactggaactggatccggcaggccgccgggaagggactgcagtggattgggcgtatgtatgccagtgggaccactaactacaacccctccctcaagagtcgagtcaccatgtcagtagtcacgtcaaagaatcaatttccctgaagttgagttctgtgaccgccgcagacacggccatttactactgtgcgagggcccgagagtttctcacctttgactcctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11648 JY8QFUQ01BURQO No results 11649 JY8QFUQ01BDDGB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CAKEGDGSVIPSPVPEWKFDSW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttgacagccatgccatgcactgggtccgtcgggctccagggaaggggctggagtgggtctcggcagttagtggtggtggccattatacatactacgcgcgctccgtgaagggccgatttaccatatccagggacaattcccgaaacatggtgtatttggagatgactggcctgacagccgaggacacggccgtatattattgtgcgaaagagggagacggatcagtgatcccgtctcctgttcctgagtggaaatttgactcctggggccagggaaccctggccacggtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 11650 JY8QFUQ01DO4D1 No results 11651 JY8QFUQ01CDQ0Y productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11652 JY8QFUQ01AW8OZ productive (see comment) Homsap IGHV4-39*02 F 942 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11653 JY8QFUQ01B9FHT No results 11654 JY8QFUQ01DI8JM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 950 83.15 227/273 nt 82.78 226/273 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [20.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,15% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); ggggggcgccatcagacgantgcgtctggggagtctctgaagatctcctgtgcagtctctggattcaccttcatcagttatggcatgagttgggtccgccaggTttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11655 JY8QFUQ01ARK8Q No results 11656 JY8QFUQ01BTIAT productive Homsap IGHV3-9*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + tctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11657 JY8QFUQ01CAR33 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEEGATGVYYVDH# out-of-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11658 JY8QFUQ01A1JGU No results 11659 JY8QFUQ01C9XIH No results 11660 JY8QFUQ01CQDC1 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt 92.89 209/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 9 9 X 9.9.X [1.17.38.11] CARGVIIMIVVV#DYW out-of-frame - in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) tctcggggacagtgtctctagcagcagtgttgttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagaggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 11661 JY8QFUQ01B27PW productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11662 JY8QFUQ01ASWW4 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKTTMTSVT#DWFDPW out-of-frame + ctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccccca 11663 JY8QFUQ01BD9FJ No results 11664 JY8QFUQ01CV6RU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame + gtctggattcacgtttagaaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11665 JY8QFUQ01CRLC9 productive Homsap IGHV3-9*01 F 901 90.41 198/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [2.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - gcctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11666 JY8QFUQ01DIGF6 unknown (see comment) Homsap IGHV4-31*06 F, or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*04 F 127 57.27 63/110 nt 10 7 X 10.7.X [1.17.1.X] null + No rearrangement found tctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11667 JY8QFUQ01C6628 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 930 92.99 199/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDPSYSYYNGLDVW in-frame - stop codons tggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtaggtctcaactattagtggtagtggtggtaggacatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca 11668 JY8QFUQ01DR5VR productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 639 77.42 168/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [0.17.38.11] CVRHVRRFWFDPW in-frame - Low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggtttcacggttcagtggctctgctatgcactgggtccgccaggcttccgggaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11669 JY8QFUQ01C9VQE unproductive Homsap IGHV3-7*03 F (see comment) 374 82.73 91/110 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD4-11*01 ORF 3 X X X X.X.X [X.X.36.11] CARDRYSSDSSYYMPNWLD#PG out-of-frame + Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttgggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11670 JY8QFUQ01DGPFY productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 11671 JY8QFUQ01C29UK No results 11672 JY8QFUQ01DE1JB productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 137 to 137 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtgGgattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccaGtttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11673 JY8QFUQ01CTI5L No results 11674 JY8QFUQ01B9H6N No results 11675 JY8QFUQ01AL0PM unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11676 JY8QFUQ01BK32N unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 705 91.07 153/168 nt 8 7 X 8.7.X [1.17.22.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BK32N ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 11677 JY8QFUQ01BHITL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11678 JY8QFUQ01BMWB9 No results 11679 JY8QFUQ01B6AL4 No results 11680 JY8QFUQ01BXKFJ unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11681 JY8QFUQ01C2B2K unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 11682 JY8QFUQ01DUWZ2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcagcctctgggggccacagcggccctggggcctcctggtcaagggactacttccccggaaccggtgacggtgtcgtggaactcag 11683 JY8QFUQ01CE6CM unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11684 JY8QFUQ01APBW6 productive Homsap IGHV3-13*01 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11685 JY8QFUQ01A7QSW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD5-12*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARDGSAHSSIYHYYYGMDVW in-frame - cctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtctcaaccattggtactagaggtagatccatatactacgcggactcagtgaagggccgattcaccacctccagagacaacgccaagaaatcactttatctggatatgcacagcctgagagccgaggacacggctatctattactgtgcgagagatggcagtgcacactcgtcgatctatcattactattacggcatggacgtctggggccaagggaccacggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11686 JY8QFUQ01BQQSG No results 11687 JY8QFUQ01ARTMQ No results 11688 JY8QFUQ01DQZSS productive Homsap IGHV3-66*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagcgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11689 JY8QFUQ01BXJ63 productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 11690 JY8QFUQ01CBV9T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11691 JY8QFUQ01ADHL2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11692 JY8QFUQ01CNKAD unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARLGQLALDY## out-of-frame + gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactgggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccttggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 11693 JY8QFUQ01BCBWP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11694 JY8QFUQ01DCDKD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11695 JY8QFUQ01BUIGH unproductive Homsap IGHV3-9*02 F 901 90.41 198/219 nt Homsap IGHJ6*02 F (see comment) 96 63.16 36/57 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [2.17.38.11] CGKDMRPGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctgggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11696 JY8QFUQ01CGD1Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.16.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 151 to 151 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactgagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtCccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11697 JY8QFUQ01ARSIX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11698 JY8QFUQ01DOVDS unproductive Homsap IGHV3-74*03 F (see comment) 697 80.56 174/216 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRGTTGWRGVDY## out-of-frame - Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcaacgtcagtggatactggatgcactgggtccgccaagtgccagggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactgggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11699 JY8QFUQ01AN2WD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaagaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11700 JY8QFUQ01BNGHT No results 11701 JY8QFUQ01C50HS productive Homsap IGHV4-61*02 F (see comment) 569 73.3 162/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARECSNSKVGPRALDSW in-frame + Low V-REGION identity (73,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcaggccgccgggaaggggctggagtgggtcgggcgtgtctatatgactggctatgtcgagaacaatccatccctctccgggcgtctctccatgtcgattgacacggcgaagaatcagttttctatgacattgacttctgtgaccgccgcagacacggccctttatttttgtgcgagggagtgtagtaattcgaaagtcggaccgagagcgcttgactcctggggcccgggaagtctggtcaccgtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11702 JY8QFUQ01AF4BD productive Homsap IGHV3-9*01 F 815 86.24 188/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame + cctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11703 JY8QFUQ01CQN1T productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaactcag 11704 JY8QFUQ01AKSJT productive Homsap IGHV3-21*04 F 995 95.41 208/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 11705 JY8QFUQ01CBA4N unknown (see comment) Homsap IGHV3-72*01 F 106 53.44 70/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11706 JY8QFUQ01A36I7 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDY* in-frame + stop codons ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactgaggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 11707 JY8QFUQ01CNKXB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 830 86.43 191/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - tagcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11708 JY8QFUQ01BSREQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11709 JY8QFUQ01CXM27 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 7 8 10 7.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcatctttgatgatttggcatgagatgggtccgccaagttccagggaaggggccacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11710 JY8QFUQ01DK61J productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11711 JY8QFUQ01AWBO4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 802 85.39 187/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 3 8 8 9 8.8.9 [2.17.38.11] CARGDVIGDCW in-frame - cctcggattgcaacttgcagagactactggatgcactgggtccgccaagctccagggaaggggctgacgtgggtctcacgtatttatggtgatgggggtaacacagcctatgcggactccgtgaagggccgattcaccatgtccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagacccgacgacacggctatatattattgtgcaaggggcgatgttatcggagactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11712 JY8QFUQ01A96Y3 No results 11713 JY8QFUQ01CPO10 productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11714 JY8QFUQ01ATPO0 No results 11715 JY8QFUQ01C8GVB productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); tctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattcTaaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11716 JY8QFUQ01CCJBJ unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11717 JY8QFUQ01BO6AT productive Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11718 JY8QFUQ01DEL2A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11719 JY8QFUQ01AZ6CA No results 11720 JY8QFUQ01C1RGN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11721 JY8QFUQ01DH08T productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaaggggctggagtgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11722 JY8QFUQ01CMH6G No results 11723 JY8QFUQ01BE0DI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1028 96.38 213/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CILLYYDSRGVFSTDYW in-frame - cagcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11724 JY8QFUQ01ANFJ6 productive (see comment) Homsap IGHV4-59*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); gtctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccctcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11725 JY8QFUQ01DP62P No results 11726 JY8QFUQ01BTSZG unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.17.38.11] CARGAPFS**C in-frame + stop codons ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11727 JY8QFUQ01CHSPD No results 11728 JY8QFUQ01CZ8TU productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccca 11729 JY8QFUQ01DI3WD productive Homsap IGHV4-61*02 F 816 85.91 189/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.38.11] CAREDYYGSGSYGRAWFDSW in-frame + ctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11730 JY8QFUQ01CTRR1 productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame + cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 11731 JY8QFUQ01B5ZOX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11732 JY8QFUQ01CA78F No results 11733 JY8QFUQ01AGZN5 productive Homsap IGHV3-53*04 F 787 85.19 184/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 7 12 8.7.12 [2.17.38.11] CARQTAPLGTLTYG in-frame - tctcgggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttacttctgtgcgagacagactgcccctttgggaactttgacttatgggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11734 JY8QFUQ01CX7WS No results 11735 JY8QFUQ01C2OUK productive (see comment) Homsap IGHV3-7*01 F 960 93.18 205/220 nt 92.27 203/220 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 6 8.8.6 [2.17.38.11] CVKSIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'AT' (2 nucleotides at position 17 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); agcctctggattcagcATtttagcagctTtttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagtgggatggaagtgataaaaagtatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagtcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 11736 JY8QFUQ01BTTRX productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11737 JY8QFUQ01AJ8IZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 7 13 8.7.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccgtcggtagcaactacatgacctgggtccgccaggctccagggaaggggctggagtggctctcagttatttacagcggtggtagtaaatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaagaacacgctgtttcttcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11738 JY8QFUQ01B335M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 11739 JY8QFUQ01C6JWV unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CVRGDYGGAPDITTT#YGLDVW out-of-frame - cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11740 JY8QFUQ01AL74E productive Homsap IGHV3-48*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame - tctggatttcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagaggcaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 11741 JY8QFUQ01CMVYS No results 11742 JY8QFUQ01AU098 unproductive Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11743 JY8QFUQ01BE6AZ No results 11744 JY8QFUQ01DSIIG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ttctggatacacatttatgaattattggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagccCcgtcctttcaaggccaggtcaccatttcagccgacaagtccaccaacaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11745 JY8QFUQ01DOMCB No results 11746 JY8QFUQ01B5SA1 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 11747 JY8QFUQ01ABG7J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 704 80.09 177/221 nt 79.64 176/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 169 82.0 41/50 nt Homsap IGHD4-17*01 F 2 8 8 16 8.8.16 [3.16.38.11] CAKDRLNGDYTFGAFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) agcctcctaaatttgacgttcaggacatatggcatgaactgggtccgccaggttccagggaagggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaacggtgactacacattcggcgcatttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11748 JY8QFUQ01AYTLP productive (see comment) Homsap IGHV3-7*01 F (see comment) 742 82.87 179/216 nt 81.94 177/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11749 JY8QFUQ01CACC0 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + ctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11750 JY8QFUQ01B617C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.56 199/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARFGPLTRPDYW in-frame + ctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11751 JY8QFUQ01C42O1 productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11752 JY8QFUQ01C4BEQ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagccCcccagagaagggtctggagtacattgggaAgcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11753 JY8QFUQ01BES25 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaccagtggtaCttttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11754 JY8QFUQ01B8P9X No results 11755 JY8QFUQ01CFJVQ No results 11756 JY8QFUQ01CMD6N No results 11757 JY8QFUQ01BFNWB productive (see comment) Homsap IGHV4-4*07 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11758 JY8QFUQ01BX39A productive (see comment) Homsap IGHV3-7*01 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaTggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11759 JY8QFUQ01BQVI7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1030 97.69 211/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGPHQYY#DYW out-of-frame - tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11760 JY8QFUQ01BVW4H No results 11761 JY8QFUQ01CGRWZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11762 JY8QFUQ01CA6E6 No results 11763 JY8QFUQ01A1IV8 productive (see comment) Homsap IGHV4-4*07 F 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 7 11 8.7.11 [1.17.37.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGCAC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgtcgccaccagtagTGGCACttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11764 JY8QFUQ01COQVB productive Homsap IGHV3-9*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame - cctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11765 JY8QFUQ01BSQ74 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11766 JY8QFUQ01BS5PY unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREVIPTATYGMDL## out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11767 JY8QFUQ01BAP9G unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*12 F 137 52.72 97/184 nt 8 7 X 8.7.X [0.17.28.X] null - No rearrangement found ctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11768 JY8QFUQ01AOU7X productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11769 JY8QFUQ01AGDVH productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame + ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11770 JY8QFUQ01BDXYZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 36 to 37 in the user submitted sequence), (cause frameshift); ctctgggttcacctttagcagctatgccatgacgtTGgggtccgccaggctccagggaaggggctggagtgggtcncaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11771 JY8QFUQ01AD0SF No results 11772 JY8QFUQ01CCD99 productive (see comment) Homsap IGHV3-7*01 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-2*01 F 3 8 7 19 8.7.19 [1.17.38.11] CVRDGGVIVVVPMDYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 2 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) ctctggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatagcgagatggaactgagaggtCattatgtggactctgtgaagggccgattcatcatctccagagacaactccaggaatttactgtatctccaaatgaacagcctgagagtcgaagacacggctgtgtattattgtgtgagagatgggggtgttattgtagtagtgccaatggactattacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11773 JY8QFUQ01BCUZS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [1.16.38.11] CAKVVWSL##YFDLW out-of-frame - in FR3-IMGT at codon 104 of V-REGION: 'C' (1 nucleotides at position 217 to 217 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgCtgcgaaagtagtctggagcctctgggtacttcgatctctggggccgtggcaccctggctcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11774 JY8QFUQ01DM4XQ No results 11775 JY8QFUQ01ABYQ3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11776 JY8QFUQ01AVMP9 No results 11777 JY8QFUQ01CITZL productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame + tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 11778 JY8QFUQ01CA0LL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 894 91.12 195/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ttctgggttcaccgtcagtagcaagttcatgagctgggtccaccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcctcagcatccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11779 JY8QFUQ01C529M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame + ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11780 JY8QFUQ01CR1J3 No results 11781 JY8QFUQ01BZBRJ No results 11782 JY8QFUQ01B2IY9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11783 JY8QFUQ01CNK6J productive (see comment) Homsap IGHV4-39*02 F 834 86.36 190/220 nt 85.91 189/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-15*01 F 1 10 7 11 10.7.11 [1.16.38.11] CARMLLRRDFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtagtatctactactggggctggatccgccagcccccaggaaagggctagaatggatcggaagtatcaactccattgggaccacctatcacaacccgtccctcaagagtcgagtcgccatgtccgttgatccgtccatgaggcacttctccctgaaagttagctctgtgaccgccgcagacacggctgtctattactgcgcgagaatgttgcttcgccgcgatttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgttgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11784 JY8QFUQ01DKALV unproductive Homsap IGHV3-7*01 F 873 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CARATNADV# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctgggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11785 JY8QFUQ01DD2N3 unproductive (see comment) Homsap IGHV4-61*02 F 883 89.09 196/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 X 10.7.X [1.17.38.11] CARDPQGYL*WW*LPLFC#MDVW out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccngttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11786 JY8QFUQ01CPIEP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11787 JY8QFUQ01BWMMA productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) tctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11788 JY8QFUQ01CP0PF productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame - ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11789 JY8QFUQ01BHYO1 No results 11790 JY8QFUQ01CO6TY unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactanttccccgaaccggtgacggtgtcgtgaactc 11791 JY8QFUQ01CQUFJ productive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11792 JY8QFUQ01BGTEO productive Homsap IGHV3-9*02 F 873 89.4 194/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaagcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgccctggtccagggcttcttccc 11793 JY8QFUQ01CHY0L productive Homsap IGHV3-9*01 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggagactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 11794 JY8QFUQ01BFKOS No results 11795 JY8QFUQ01AIZWS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt 11796 JY8QFUQ01C4CJF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc 11797 JY8QFUQ01DH0JE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11798 JY8QFUQ01BAV34 No results 11799 JY8QFUQ01COL6G productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11800 JY8QFUQ01A5Z17 productive Homsap IGHV3-7*03 F 845 88.37 190/215 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [0.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + ctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattctctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 11801 JY8QFUQ01CNSWO No results 11802 JY8QFUQ01AYXF7 No results 11803 JY8QFUQ01C7QU9 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARQSVPYTEYFNWFDPW in-frame - tctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcagggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagagccgaggacacggctgtgtattattgtgcgagacagtctgtaccatataccgaatatttcaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11804 JY8QFUQ01AL6UR productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame - tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11805 JY8QFUQ01BHJ1F No results 11806 JY8QFUQ01CMK2O No results 11807 JY8QFUQ01CHXPU productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 11808 JY8QFUQ01CSSV0 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 107 67.31 35/52 nt 7 X X 7.X.X [X.9.X.X] null - No rearrangement found gattcacctttagtagttactggatgcactgggtccagggcttcttccccca 11809 JY8QFUQ01A41PO No results 11810 JY8QFUQ01BYMB6 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11811 JY8QFUQ01DVLTC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 876 96.77 180/186 nt 8 8 X 8.8.X [1.17.27.X] null - No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcca 11812 JY8QFUQ01A5Y86 No results 11813 JY8QFUQ01DO1IH No results 11814 JY8QFUQ01C26JF No results 11815 JY8QFUQ01CSAYF No results 11816 JY8QFUQ01BZDNI productive (see comment) Homsap IGHV4-61*02 F 817 85.59 190/222 nt 84.68 188/222 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 10 7 15 10.7.15 [2.17.38.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); gtgtctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttatCaaaagtggcgacacagtgtacaacccctAccctcggggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11817 JY8QFUQ01AO4M7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD3-9*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARSATGYYDGMDFW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtaggtactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatgaatagtgatgggagtattataaactacgcggactccgtgaagggccgattcaccatctccagagacaacgcctggaacacgctgtatctgcaaatgaacagtctgggagccgaggacacggctgtgtattattgtgcaaggtctgcgactggctactatgacggcatggacttctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 11818 JY8QFUQ01DNGX5 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 11819 JY8QFUQ01CQMQ4 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta 11820 JY8QFUQ01BOTUY No results 11821 JY8QFUQ01BOD5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1076 99.54 217/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD2-2*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKFMGSCSSTSCPQLVRPPG in-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaagacacggccgtatattactgtgcgaaattcatggggagttgtagtagtaccagctgcccacaactggttcgaccccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11822 JY8QFUQ01CCXBP No results 11823 JY8QFUQ01CB4XO productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11824 JY8QFUQ01CCZ8L productive (see comment) Homsap IGHV3-7*01 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.16.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11825 JY8QFUQ01AH15Z No results 11826 JY8QFUQ01BVEKE No results 11827 JY8QFUQ01A3S3N No results 11828 JY8QFUQ01AP99G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagcggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11829 JY8QFUQ01AVPHL No results 11830 JY8QFUQ01DN21P productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11831 JY8QFUQ01DNC8V productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 11832 JY8QFUQ01AJ7S8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11833 JY8QFUQ01BH87Y unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 120 100.0 24/24 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found cctctggattcactttcagtaacg 11834 JY8QFUQ01DDAI0 No results 11835 JY8QFUQ01ALDQF No results 11836 JY8QFUQ01B5URA productive (see comment) Homsap IGHV4-34*06 F (see comment) 682 80.19 170/212 nt 79.72 169/212 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 7 7 14 7.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tccatggtgggtccctcagggttaccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11837 JY8QFUQ01CJGZ4 No results 11838 JY8QFUQ01CTRV5 No results 11839 JY8QFUQ01AH1IP No results 11840 JY8QFUQ01B4N37 productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagtacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11841 JY8QFUQ01ABFEP unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 11842 JY8QFUQ01DVKNZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDMGGDYYIFHYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); cttctggattctcctttagcaactatgccctggcctgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactCccgtgaggggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggatatgggtggcgactattacatctttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaa 11843 JY8QFUQ01AL4SK unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 603 75.12 163/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (75,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11844 JY8QFUQ01BRC20 No results 11845 JY8QFUQ01AGHVV No results 11846 JY8QFUQ01DNFWA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 661 78.24 169/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11847 JY8QFUQ01C95LE productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11848 JY8QFUQ01DIFBM unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 459 72.78 131/180 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11849 JY8QFUQ01C6FJP productive Homsap IGHV1-58*02 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame - tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11850 JY8QFUQ01A9LZM productive Homsap IGHV4-4*07 F (see comment) 515 70.59 156/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-1*01 F 2 8 7 16 8.7.16 [3.17.38.11] CARERISSGGGPRHLEPW in-frame + Low V-REGION identity (70,59% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcactggaggtccggtcaacagtaatgactgctcttggacatggatccgagagtccgccgggaggggactggagtggattggccgtgtccatatgaatggccagaccgactacaatccatccttcggcagtcgtctcgccatgtccattgacacagtcaagaatgaattctcccttcgaatggtctctgtgaccgccgcagacacggccctatattactgtgcgcgagaacgtataagttccggtggcgggccgagacaccttgaaccctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11851 JY8QFUQ01BHSKJ productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatgGgacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11852 JY8QFUQ01CYWHB productive Homsap IGHV4-61*02 F (see comment) 677 78.73 174/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARDRRRSIAGARHFDSW in-frame + Low V-REGION identity (78,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggccccaccatcgatgatggtgatttgtggacctggatccggcagcccgccggcaagggactggaatggatcggttatgtctatgatgggcggggcaccaactccaacccctccctccggagtcgcgttaccctgtcacaagacacctcaaacaatcagttcttcttgaggttgaagtctgtgaccgcctcagacacggccgtctattactgtgcgcgagaccgccgtaggtcgattgccggagcgagacactttgactcctggggccagggaatcctggtcaccgtcgccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11853 JY8QFUQ01CTZBB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame + tggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11854 JY8QFUQ01BLSPR productive (see comment) Homsap IGHV1-3*01 F 940 93.06 201/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRYDSSGRGHEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'T' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gctggatacaccttcaccagtttcagtatccattgggCtgcgccaggcccccggacaAaaggcttgagtggatgggatggatcaaTcggtggcaatggtaacacaaaatattcacagaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11855 JY8QFUQ01B6SNK unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11856 JY8QFUQ01BZ3QE unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11857 JY8QFUQ01CCYZF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.16.38.11] CVRLDYYGSGSSYSGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) gtctggtggctccatcagtggtactccttactactggggctggatccgccagcccccaggtaagggctggagtggattgggcatgtatatcacagagggaccacctactacaacccgtccctcaagagtcgagtcgccatatccgtagacacgtccgagaaccggttctccctgcagttgaactctgtgaccgccgcagacacggctgtatattactgtgtgagactggattactatggttcgggaagttcttatagtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11858 JY8QFUQ01C7RDZ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD3-10*01 F 1 8 8 19 8.8.19 [1.17.38.11] CARPAFLWFGDLPAEDGFDVW in-frame + ttctggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcagtaccgcctaccttcagtggagcagtctagcgacctcggacaccgccatgtattactgtgcgagaccagcttttctctggttcggggacttaccggccgaggatggttttgatgtctggggccaaggaacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 11859 JY8QFUQ01BZA3D No results 11860 JY8QFUQ01BM2P8 No results 11861 JY8QFUQ01BQLZD No results 11862 JY8QFUQ01AHSIQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 92.38 194/210 nt 91.9 193/210 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 13 7.8.13 [X.17.38.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) attcacctttagtagtttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11863 JY8QFUQ01B1D7U productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CARGIKAVPGAIAYYYYGMDVW in-frame + ctccggattcacctttagtaactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgacaaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagaggaattaaggcagtaccaggtgctattgcctactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11864 JY8QFUQ01BGF48 unknown (see comment) Homsap IGHV4-39*02 F 925 90.99 202/222 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctgggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaagggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtgggggccagggaacccctggtcaccntctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11865 JY8QFUQ01A0K4F No results 11866 JY8QFUQ01AWSX6 productive Homsap IGHV3-48*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11867 JY8QFUQ01C95YJ productive (see comment) Homsap IGHV1-3*01 F 840 88.32 189/214 nt 86.92 186/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); tggatacagGcttcactaatcacattatccattgggtgcgccaGggcccccggacaagggcttgagtgggtggGggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11868 JY8QFUQ01ASA99 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 697 92.59 150/162 nt 91.98 149/162 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 X 7 13 X.7.13 [X.9.38.11] CARRGSYGSGSYYPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); gggaaggggctggagtggattgggagtatGcttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11869 JY8QFUQ01BEEO9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSGYYSTGYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'CA' (2 nucleotides at position 82 to 83 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggatttaccttcagtctctatagaatgaactgggtccgccaggctccagggaagggactggagtggtctcatccattCAtctagtaccagtagttacatttattatgcagacccagtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11870 JY8QFUQ01BHIQA productive (see comment) Homsap IGHV3-7*01 F 863 87.5 196/224 nt 87.05 195/224 nt Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [3.17.38.11] CVRGQVGANPLTTG in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); agccctctggggttcaaccctttggtcactattGggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgtcgagaactcactatatttacaaatgaacagcctgagagacgacgacacggctgtatattactgtgtgagaggtcaagtgggagctaatcccttgactactggggccagggggaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11871 JY8QFUQ01BI9J9 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatCggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11872 JY8QFUQ01DS89P No results 11873 JY8QFUQ01AYCDB No results 11874 JY8QFUQ01B1Q4T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 11875 JY8QFUQ01AWPED productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgagacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11876 JY8QFUQ01DVQNE No results 11877 JY8QFUQ01C9JK6 productive (see comment) Homsap IGHV3-11*01 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD6-13*01 F 1 8 8 9 8.8.9 [2.17.38.11] CARGSSWYRSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 91 to 99 in the user submitted sequence), (do not cause frameshift); gcctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacaacctaagagccgaagacacggccttctattactgtgcaagagggagcagctggtaccgctcctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctaagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11878 JY8QFUQ01DCH1D productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11879 JY8QFUQ01BBJPY productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1004 95.87 209/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARHVGNSGFDSSQFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'GA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); gttctggatacagctttaccacctGActgggatcggctgggtgcgccCaaatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcatccgaaaagtccatcagtaccgcctacctgcagtggagcagcctgacggcctcggacaccgccatgtattactgtgcgagacatgtgggaaatagtggcttcgactctagtcaatttgactactggggccagggaacccccgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11880 JY8QFUQ01BJE4C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 11881 JY8QFUQ01BA4UC No results 11882 JY8QFUQ01AOTOC productive Homsap IGHV3-11*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARRLLSSGWPPHEWGSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgactactacatgtcgtggatccgccaggctccaggaaaggggctggagtgggtctcatacattagtagtagtggtaattccatatactacgcagactctgtgaggggccgattcaccacctccagggacaacgccaagaattcgatatatctacaaatgaacagcctgagagccgacgacacggccgtttatttttgtgcgagaagacttctgagcagtggctggccaccccacgagtggggctcctggggccagggaacccacgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11883 JY8QFUQ01AN6PU productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11884 JY8QFUQ01AA27V productive Homsap IGHV4-59*08 F 917 92.09 198/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame - tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11885 JY8QFUQ01CM142 No results 11886 JY8QFUQ01BQXPV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 11887 JY8QFUQ01CQ9IE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactgggtccgcaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11888 JY8QFUQ01CRTE6 unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11889 JY8QFUQ01DMLOV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11890 JY8QFUQ01BEKLK productive Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame - tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11891 JY8QFUQ01BH3X1 productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11892 JY8QFUQ01CEVW7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11893 JY8QFUQ01A6X8C No results 11894 JY8QFUQ01AP01Y unknown (see comment) Homsap IGHV1-2*02 F 551 91.54 119/130 nt 8 8 X 8.8.X [X.17.10.X] null + No rearrangement found ggatacaccttcaccggcacctatatacactgggtgcgacaggcccctggacaagggcttgagtgggtgggattaatcaaccctagcagtggtggcacagagtctgcacagaagcttcagggcagggtca 11895 JY8QFUQ01C583V productive (see comment) Homsap IGHV3-30*01 F 874 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARDSVPRASEAAYHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); gcctctggattcGtccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttaCtttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11896 JY8QFUQ01AKHC5 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame - ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11897 JY8QFUQ01B42UT productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11898 JY8QFUQ01CC0WF productive Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F 402 92.55 87/94 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 X X 16 X.X.16 [X.X.31.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccgagggcttcttcccca 11899 JY8QFUQ01DCV1U No results 11900 JY8QFUQ01BJERG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.16.38.11] CAKRLQAVADDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) gcctctggattcatctttagtagctatgccatgggctggtccgccaggctccagggaagggctgagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11901 JY8QFUQ01AP1TI productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-7*01 F 3 8 7 15 8.7.15 [1.16.38.11] CIADLPDSAENYPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 9 nucleotides (from position 88 in the user submitted sequence), (do not cause frameshift) cctctggattcacttttagtggcgcctggatgagctgggtccgccaggctccagggaagggctggagtgggttggccgtgttagaagcggtgggacaacagactaccctgcacccgtggaaggcagattcaccatctctagagatgatcgaaaaaacacgttgtatctggaaataagtagcctgaaaatcgaagacacagccgtatattactgtatcgcagatttgcccgactcggcagagaactatccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 11902 JY8QFUQ01C6CX9 No results 11903 JY8QFUQ01DN6YG productive (see comment) Homsap IGHV3-7*01 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 136 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 7 10 8.7.10 [1.17.37.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 92 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 98 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ctctggattcatctttggacactattggatgagttgggtccgccagattccagggaagggtctggagtgggtggccaacatacaacaagataggaagaattattatctggactctgtgaagggccgatttaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgagacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggantcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11904 JY8QFUQ01BRDEV unproductive Homsap IGHV4-31*06 F 821 85.91 189/220 nt 85.45 188/220 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-16*02 F 1 10 7 X 10.7.X [1.17.38.11] CARRSRGPIQGTPFDH## out-of-frame + in CDR2-IMGT at codon 64 of V-REGION: 'AGTCCCCACTAC' (12 nucleotides at position 102 to 113 in the user submitted sequence), (do not cause frameshift); tctctggagactccgtcaccggaactacttcgtactggagttggatccgccagagcccagggaagggcctggagtggattgggtacgtcttttacaatgagAGTCCCCACTACagcacctactacaggccgtccctcaggagtcgagtcactatttcagtagacacgtctaggaaccagttttccctggaactgagctctgtgactgtcgcggacacggccatgtatttctgtgcgagacgatcccgggggcccatccaggggacaccctttgaccactggggccccgggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 11905 JY8QFUQ01CDM6X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 11906 JY8QFUQ01B5RAR No results 11907 JY8QFUQ01BGC5I productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F (see comment) 769 84.26 182/216 nt 83.33 180/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 1 8 7 13 8.7.13 [2.17.38.11] CASVRPSGERFFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gtctctggtggctcgctcacgggtttcaagtggggctggatccggcagcccccaTggggagggactgCaattggattggacatatctctttcgttggggacaccagttatgacccttccctcaggagtcgagtcaccatttcagtcgacacgtccaagaaccagttctccctgaaactgaactctatgactcctgcggacacggccgtctattactgtgcgagcgtgcgtccttcgggagaacggttcttcgacttctggggcctgggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11908 JY8QFUQ01BQZF6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 781 83.78 186/222 nt 82.88 184/222 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); caatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11909 JY8QFUQ01BHETC No results 11910 JY8QFUQ01CLHYU productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11911 JY8QFUQ01DMPG1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcgatcttcccccttggcaccctcctccaagagcacctcctggggggcacagcggccctgggctggcctggtcaggcactacttccccgaaccggtgacggtgtcgtcggaactca 11912 JY8QFUQ01AQXHN productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggtaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11913 JY8QFUQ01DNQEI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11914 JY8QFUQ01BPU5X unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 625 93.06 134/144 nt 90.97 131/144 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 7 1 X 7.1.X [2.X.38.11] CVSDLAGQKGF## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01BPU5X ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 28 in the user submitted sequence), (do not cause frameshift) gcctcaggattcaccttcagtagctacacagatcacgcggactccgtgaaTgggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11915 JY8QFUQ01DMK96 productive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 11916 JY8QFUQ01AN9TH productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11917 JY8QFUQ01B9YIT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11918 JY8QFUQ01CNS5P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1010 97.64 207/212 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [0.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 11919 JY8QFUQ01A4B5Y No results 11920 JY8QFUQ01ANBT8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 135 56.35 71/126 nt 8 8 X 8.8.X [1.17.7.X] null + No rearrangement found stop codons ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc 11921 JY8QFUQ01C7C09 No results 11922 JY8QFUQ01DHFSJ productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11923 JY8QFUQ01B2TR5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 11924 JY8QFUQ01CM25P unproductive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F (see comment) 380 82.3 93/113 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 X X X X.X.X [X.X.37.11] CAREFEIWSRPAL*S#W out-of-frame - stop codons Low V-REGION identity (82,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtggctcgatcagtggagtcgagtcatcctgtcagtagacacgtccaagaacctgttctccctgaacctgaggtctgtgaccgccgcggacacggccgtgtactactgtgcgagagaattcgaaatttggtcgcgtcctgcactttgatcagtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11925 JY8QFUQ01BXDIA No results 11926 JY8QFUQ01BFEVB productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 644 93.84 137/146 nt 93.15 136/146 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 X 12 8.X.12 [1.8.31.11] CARRDVGLHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 54 in the user submitted sequence), (do not cause frameshift) gttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11927 JY8QFUQ01CC9GA productive Homsap IGHV3-48*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARDHWDNNGYHWFDPW in-frame - ctctggactcatcttcagtgacaacagcatgaactgggtccgccaggctccagggaaggggctggagtggattgcatacatcagtgctggtagtgtaatgatatactacgcagactctgtgatgggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtatattactgtgcgagagatcattgggacaacaatggttatcactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccgaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11928 JY8QFUQ01BM7QO unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11929 JY8QFUQ01CSP1R productive Homsap IGHV3-11*01 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDDSCSGGSCYEYW in-frame - acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacgcggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11930 JY8QFUQ01B5SAT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 98.62 214/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccGttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11931 JY8QFUQ01DVWWV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggaccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 11932 JY8QFUQ01CKHYH productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11933 JY8QFUQ01CR951 No results 11934 JY8QFUQ01AUXA6 productive Homsap IGHV4-30-4*07 F, or Homsap IGHV4-31*01 F or Homsap IGHV4-31*02 F or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F or Homsap IGHV4-31*06 F or Homsap IGHV4-31*07 F or Homsap IGHV4-31*08 F or Homsap IGHV4-34*09 F or Homsap IGHV4-59*06 F (see comment) 253 75.27 70/93 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 X X 18 X.X.18 [X.X.31.11] CARSAYCGADCYSADYLQHW in-frame - Low V-REGION identity (75,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctggtggctccgtcagcaacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11935 JY8QFUQ01AELDS productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD4-23*01 ORF 2 8 7 8 8.7.8 [1.17.38.11] CGRGDGGDLW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcacggttgaggattatggcgtgagctgggttcgccaagttccagggaaggggctggagtgggtctctggtcttaatttgaatggtgccacaggttatgcaaagtccgtgacgggccggtttaccatctccagagacaacgccaagaactccctgtatttggaaatggatagtctgagagtcgaagacacggccttctattattgtgggagaggggacgggggtgacctctggggccggggaatcctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11936 JY8QFUQ01ALQBA No results 11937 JY8QFUQ01C6MAS unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11938 JY8QFUQ01AB3G5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 942 92.27 203/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + ctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtcggtcatcgcctgcctggtccagggcttcttcc 11939 JY8QFUQ01AY8MO productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 857 89.62 190/212 nt 89.15 189/212 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [0.17.38.11] CARGHRNPGVWDLGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); acagtgggtccttcagtggttacctctggacctggatccgccagtTcccccgggaaggggctggagtggattggagaaattaattatagtgggagaaccaactacaacccgacccttgagagtcaagtcaccatttctgtagacacgtccaagaaccaattctccctgaagcttacctctgtgaccgccgcggacacggctgtctattactgtgcgagaggtcacagaaatccgggagtttgggacctcggtctggacgtctggggccaggggaccacggtcatcgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11940 JY8QFUQ01BQGF2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame - ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11941 JY8QFUQ01BGB91 No results 11942 JY8QFUQ01B4712 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11943 JY8QFUQ01BSKS0 No results 11944 JY8QFUQ01APE2N unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1055 100.0 212/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [0.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11945 JY8QFUQ01C1Z35 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 928 91.78 201/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gcctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11946 JY8QFUQ01C5Q2O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 11947 JY8QFUQ01BYM54 productive (see comment) Homsap IGHV3-33*03 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD4-17*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVRGQGLRGGALDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) cgtctggattcaGccttcagtagttatgccatgcactgggtccgccaggctccaggcaggggactggagtgggtggcacttatatactatgatggaagtactaatactttgcagactccgtgaggggccgattcatcctctccagagacaactccaagagaaccctttatctggaaatgaacagcctgcgagccgaggacacggctgtatattactgtgtgagaggccagggattacggggaggtgctcttgatgtctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgcggaactcag 11948 JY8QFUQ01CP0ZY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11949 JY8QFUQ01CDZX3 No results 11950 JY8QFUQ01A4ICZ No results 11951 JY8QFUQ01CXJ2U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11952 JY8QFUQ01DOZ40 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 80 51.13 68/133 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11953 JY8QFUQ01C6WJS productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11954 JY8QFUQ01B4LPF productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11955 JY8QFUQ01C555O unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 11956 JY8QFUQ01BMO6L productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11957 JY8QFUQ01BG7VS No results 11958 JY8QFUQ01AQMRJ unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-49*02 F or Homsap IGHV3-49*04 F 120 76.19 32/42 nt 8 X X 8.X.X [0.5.X.X] null - No rearrangement found tggattcagcctcgccacttatagtatgagttgggtccgcca 11959 JY8QFUQ01CP6CD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame + tctctggtgactccattggtagcagtgcctactactggggctgggtccgccagcccctcgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcatttccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11960 JY8QFUQ01DGVDO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactataccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccGagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11961 JY8QFUQ01AZJZS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11962 JY8QFUQ01ADD0I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcgatcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11963 JY8QFUQ01DFDVP unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 770 83.49 182/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11964 JY8QFUQ01ABYO5 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); cctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagGggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11965 JY8QFUQ01DD9P0 productive Homsap IGHV3-30*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYLDYW in-frame + cctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11966 JY8QFUQ01C0163 No results 11967 JY8QFUQ01DSWQX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 912 90.13 201/223 nt 89.24 199/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11968 JY8QFUQ01AKBXE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.16.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagttatagcatgcactgggtccgccagactccagggaagggactggagtggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11969 JY8QFUQ01CF9JY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKEEGATGVYYVDH# out-of-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactgggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11970 JY8QFUQ01BX4H4 productive Homsap IGHV4-4*07 F 854 88.84 191/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 8 7 10 8.7.10 [1.17.38.11] CAKDIQDEDNYW in-frame + tctctggtggctccgtcaatggcatttactggagttggattcgacaatccgccggaaagggactggagtggattgggcgcatccataccagtgggagcaccaactacaacccctccctcaaaagtcgagtcaccatgtcgatagacacgtccaagaaccagttctccctaaggttgacctctgtgaccgccgcggacacggccatttattactgtgcaaaagacatacaggatgaggataattactggggccagggagccctggtcaccgtctccgcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 11971 JY8QFUQ01DRMJJ productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 11972 JY8QFUQ01CDUFD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CTRQTGNYYYFGVDVW in-frame - gcctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11973 JY8QFUQ01CNBO4 No results 11974 JY8QFUQ01CMRUS No results 11975 JY8QFUQ01CUTRF productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaCcctttggttattatggcatgaactgggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11976 JY8QFUQ01DMCIU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11977 JY8QFUQ01BU84D productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 2 8 7 12 8.7.12 [2.17.38.11] CAVSTTTWGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); gtctatggtgggtccttcagtggttactactggagctggatccgccagcccccaggggaggggctgcagtggattggaagagtcaatcatagtggaagcaccagctacaacccgtccctcaagagtcgagtcaccatgtcactagacacgtccaagacccacCttttccctgaagctgacctctgtgaccgccgcggacacggctgtgtattactgtgcggtgtctactaccacctgggggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11978 JY8QFUQ01BTSZN productive (see comment) Homsap IGHV4-31*06 F 979 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [2.17.38.11] CARDRGPSSSSKMEYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gtctctggtgCcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagggaagggcctggagtggattgggtacatctattacagtgggagcgcctactacaacccgtccctcaagagtcgagttgccatatcaatagacacgtctaagaaccagttctccctgaacttgagttctgtgactgtcgcggacacggccgtttattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11979 JY8QFUQ01C8YSA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVMWGVTGPIDPFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttacctactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactgggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11980 JY8QFUQ01DDP4N productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 11981 JY8QFUQ01AS99Y unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 866 89.67 191/213 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD5-18*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREFRAPSLARYGMDV## out-of-frame - tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctgggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11982 JY8QFUQ01BGTYY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 495 69.59 151/217 nt 69.12 150/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] VHT#AFW out-of-frame + Low V-REGION identity (69,59% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctgaggacaactttggtgaacacgccatgggatggatccgccagtctccgggggggaAttcttcagtgggtcgctgcgatcagtggtgacggactgacggcgtttcacgcagacttcgtggagggtcgattcagcatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctattttgtgcacacactgccttctggggccggggatcccgagtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 11983 JY8QFUQ01BGYPI No results 11984 JY8QFUQ01CLMSI productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 820 86.3 189/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKVGNLYFFEYW in-frame - gcctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11985 JY8QFUQ01DAXG2 productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11986 JY8QFUQ01CLAU5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11987 JY8QFUQ01BB8IM productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 880 88.29 196/222 nt 86.94 193/222 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 10 7 16 10.7.16 [2.17.38.11] CTNDHSMAVSAKHAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); gtctctggtgcctccGatgagcaCgtagtgcatactactggggctgggtccgccagAAcccccgggaagggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11988 JY8QFUQ01DKOB5 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt Homsap IGHJ3*02 F (see comment) 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11989 JY8QFUQ01CCIG5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - tggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 11990 JY8QFUQ01A2S2S productive (see comment) Homsap IGHV1-58*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); tggattcacctttaAaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11991 JY8QFUQ01A3591 productive (see comment) Homsap IGHV3-30*07 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*01 F 3 8 8 9 8.8.9 [2.17.38.11] CANEEVPNDWW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gcctctggattcacgttcaacagttTatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacactttgtatctacaaatgcacagcctgagagccgaagacacggccacatattactgtgcgaatgaggaggtcccgaatgactggtggggccagggaaccctggtcaccgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11992 JY8QFUQ01CDKLK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcaaggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 11993 JY8QFUQ01BQA57 No results 11994 JY8QFUQ01CITBS productive Homsap IGHV3-7*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CATSPSVGPTTVGYW in-frame - cctctggattcacctttagaaactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgacagatggaggtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgccacatcccctagtgtgggacctacgacggtgggctactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 11995 JY8QFUQ01CSDDS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11996 JY8QFUQ01B1Y16 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD2-2*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKDPQQLLAEVNWFDPW in-frame - ctctggattcacttttagaagttatgccatgagttgggtccgccaggctccagggaaggggctagagtgggtctcatctatcagtggtaatggtgataagacaaagtacgcagactccgtgaagggccggttcaccatctccagggacaattttaagaatacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagatcctcagcagctattggcagaggtaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 11997 JY8QFUQ01BKT6G productive Homsap IGHV3-66*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-16*01 F 2 8 7 13 8.7.13 [2.17.38.11] CAALHDPPWGWLDPW in-frame - agcctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 11998 JY8QFUQ01BK0R7 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 11999 JY8QFUQ01DTVX5 productive (see comment) Homsap IGHV3-48*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggAtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12000 JY8QFUQ01BTIZE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 12001 JY8QFUQ01CX200 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggaAttcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12002 JY8QFUQ01CASAF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12003 JY8QFUQ01AS9TZ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 906 90.45 199/220 nt 89.09 196/220 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-14*01 ORF 3 10 7 13 10.7.13 [1.16.38.11] CARHLQYNRHGFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcagcagtagtcattactactgggctggatccgccagaccccaggAaaaggggctggagtggCtttgggacaatctattatagcggaagcgcctacatcaacccgtccctcaagagtcgagtcaccatttccgttgacatatctaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattactgtgcgagacacctgcaatataatcgacatggttttgatttctggggccaggggacaacggtcaccgtctcttcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12004 JY8QFUQ01AD9HE productive (see comment) Homsap IGHV3-7*01 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [2.17.37.11] CAISSAYFSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 11 to 12 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 171 in the user submitted sequence), (cause frameshift) agcctctagaGTtcagcctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12005 JY8QFUQ01DC901 productive Homsap IGHV1-2*02 F 1029 98.13 210/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARAIDFGSGDKRGFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcaccggctactctatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctaacagtggtggcacaaactatgcacagaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggagctgagcaggctgacatctgacgacacggccgtgtattactgtgcgagagccatcgattttgggagtggtgacaaacgggggtttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12006 JY8QFUQ01DNXN3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggc 12007 JY8QFUQ01DLPSL No results 12008 JY8QFUQ01BJ7AA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12009 JY8QFUQ01CMQUZ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame - ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12010 JY8QFUQ01A897D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12011 JY8QFUQ01CUNNM unknown (see comment) Homsap IGHV3-7*03 F (see comment) 696 80.37 172/214 nt 79.44 170/214 nt 7 8 X 7.8.X [1.16.38.X] null + No rearrangement found Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tctggattcagtttagtgacttttggatgcactgggtccgccaggctccagggaagggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12012 JY8QFUQ01A4918 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 133 63.64 49/77 nt 8 X X 8.X.X [1.16.X.X] null - No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 12013 JY8QFUQ01CGD6K No results 12014 JY8QFUQ01DHTWB productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12015 JY8QFUQ01DTV3B productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 812 93.51 173/185 nt 92.97 172/185 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.6.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 33 nucleotides (from position 36 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcagtagttactggatgcactgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12016 JY8QFUQ01A1GHG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CVRDRSGQAVGYW in-frame - tggatacacgtttatgaattactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12017 JY8QFUQ01APIZM No results 12018 JY8QFUQ01A4CXE unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 720 81.57 177/217 nt 80.65 175/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGGN*#FDYW out-of-frame + stop codons Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 104 of V-REGION: 'G' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); ctctggatttacatttagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgagaggccgcttcaccatctctagagacgacgccAaagaattcactttatctgcagatgaacaacctgagaggcgaggacacggctgtctatttttgGtgcgagaggggggaactgattttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 12019 JY8QFUQ01CA9L2 No results 12020 JY8QFUQ01AK4VK No results 12021 JY8QFUQ01A65AM No results 12022 JY8QFUQ01AE45Z productive Homsap IGHV4-61*02 F (see comment) 888 89.09 196/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] XARQGDSSGPWNDYW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgngcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12023 JY8QFUQ01AQNXS unproductive (see comment) Homsap IGHV3-11*01 F 891 90.32 196/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [2.17.38.11] CARDGPPY*YGSHGNSFDQW in-frame + stop codons in FR2-IMGT at codon 50 of V-REGION: 'ACC' (3 nucleotides at position 65 to 67 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'T' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 56 of V-REGION: 2 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) cctgctggattcagcttcagtgactactacatgagttgggtccgccaggctccaggggaaggggACCtggagtgggtttcatgcatgcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatTctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttattgatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12024 JY8QFUQ01BNM8M No results 12025 JY8QFUQ01B9YI8 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 899 88.89 200/225 nt 88.44 199/225 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [2.17.38.11] CTTAPSETYATEYFAMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'GA' (2 nucleotides at position 26 to 27 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagtaatgGAtttggatgagttgggnccgtcaggctccgagggaagggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12026 JY8QFUQ01C7R8G productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARHLTNSDVVHHFYSGVDVW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcagtaatgataattatttctgggcctgggtccgccagtccccaaggaagggtctgcagtggattggcagtatgtattatagtgggggcaccttttacgacccgtccctcaagggtcgaatcaagttgtccgttgacgtgtcgaagagccacttcctcctgaacctgacctctgcgaccgccgcagacacggctgtctattactgtgcgaggcatttgaccaactcagatgtggtccatcacttctactccggagtagacgtctggggcctcgggaccacggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12027 JY8QFUQ01B0DN3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12028 JY8QFUQ01BI2HT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 408 87.62 92/105 nt 86.67 91/105 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 12029 JY8QFUQ01CZB7V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tctggattcacGatttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttaCctggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12030 JY8QFUQ01AFVJE No results 12031 JY8QFUQ01CCPRT No results 12032 JY8QFUQ01BUN9C productive Homsap IGHV1-3*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 12033 JY8QFUQ01CKWIB productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12034 JY8QFUQ01CJ55N productive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12035 JY8QFUQ01AHXZ2 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARTETQGGYSYGIDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcaacttcagtggcCtataccatgacttgggtccgccaggctccggggaaggggctggagtgggtctcatccattagtagtggcagcaattacacatatttcgcagactctgtgaagggccgatgcaccatctcgagagacaacgccaagaaatcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagaacggagacccaaggtggatacagttatggcattgattcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12036 JY8QFUQ01BD4L4 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12037 JY8QFUQ01AV7LU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - cttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12038 JY8QFUQ01BVNQE unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYG#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12039 JY8QFUQ01BA2X2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12040 JY8QFUQ01B921H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gcctctggattcatctttagtaattatgccatgagttgggtccgccaggCccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12041 JY8QFUQ01BI52Z unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-71*03 P or Homsap IGHV3-72*01 F or Homsap IGHV3-73*01 F or Homsap IGHV3-73*02 F 87 90.48 19/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggggtcaccttcagtga 12042 JY8QFUQ01DT9N2 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12043 JY8QFUQ01A8VFH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt 94.95 207/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); cctctggattcagcttcaatagttactggatgcactgggtccgccaagctccaggGgaaggggctggtgtgggtctcacatattaatattgatgGggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12044 JY8QFUQ01BNYDH productive (see comment) Homsap IGHV4-61*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 9 7 15 9.7.15 [1.17.38.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) tctctggtgctccatcagcagtggtagtttctacCtggagctggatccggcagcccgccgggaagggactggagtggatggggcgtgtctatgccagtggaaccaccaagttcaacccctccctcaagagtcgagtcactttatcagtagacacgtccaagaaccagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12045 JY8QFUQ01B55L9 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ6*01 F (see comment) 90 60.32 38/63 nt 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFGPY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*02 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ccctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggaccgtactggggccaggaacctggtcaccgtctcctcagctccagccaagggccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12046 JY8QFUQ01DDKG0 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*15 F or Homsap IGHV3-30*17 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKDFYYGCDYW in-frame + ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 12047 JY8QFUQ01CGQUY No results 12048 JY8QFUQ01B6K1Q productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 868 87.11 196/225 nt 85.78 193/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [2.17.38.11] CNADVPSPLAQNDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 61 of V-REGION: 'A' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gcctctgggttcGattttcagtgatgcctggatgagttgggtccgccaggctccagggaaAggctctggagtgggttgcccgtataaaaacttttggtgAacggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcgaaaaaaaggctgtatctgcaaatggacagcctgagaatcgaggacacagccaagtattactgcaacgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12049 JY8QFUQ01BBN07 productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12050 JY8QFUQ01AOWYY No results 12051 JY8QFUQ01DKKPW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12052 JY8QFUQ01ADMS9 productive (see comment) Homsap IGHV3-7*01 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 2 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) cctctggattacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12053 JY8QFUQ01CPG9I productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame - tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12054 JY8QFUQ01BFMXR No results 12055 JY8QFUQ01DKR74 productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + cctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 12056 JY8QFUQ01BINLE productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12057 JY8QFUQ01CNU0H productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt 97.21 209/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctgggtggctccatcagtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12058 JY8QFUQ01BLCL3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARGEFYYETSGRRGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cagcctctggaGttcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12059 JY8QFUQ01CXKJE No results 12060 JY8QFUQ01CL9NP No results 12061 JY8QFUQ01B33I4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] RAKG*SLRPNIELQ#W out-of-frame - stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcagcGtaggccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtaatagtggtggtagtagatactacgcagactccgtgaagggccggttctccatctccagagacagttccaagaacacactgcatctgcaaatgaacagcctgagagccgaggacacggccatatattaccgtgcgaaagggtagagtctacgacctaacatcgagctacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12062 JY8QFUQ01A7OU8 No results 12063 JY8QFUQ01C3609 productive (see comment) Homsap IGHV3-72*01 F 1033 96.4 214/222 nt 95.95 213/222 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 9 13 8.9.13 [1.17.38.11] CVRGLHSNYYGMDVR in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 91 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcaggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12064 JY8QFUQ01DDR9P productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 914 89.43 203/227 nt 87.67 199/227 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 10 22 8.10.22 [2.17.38.11] CATDRPYYKNAAGRLWYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); agtgctctggaCttcactttcactaacgcgtggatgagttgggtccgccaggctccaGgggaaggggctggagtCgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaAaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12065 JY8QFUQ01DBBY5 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12066 JY8QFUQ01CEP1K productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*02 F 3 8 8 22 8.8.22 [1.17.38.11] CARGGKSPRRDIIQGVTVDALDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tctggagacaccttcagtagccaagccatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggcgggatcatccctaCtttttgatatgacgaggtacccacagaggttcgagggcagaatcacgattaccgcggacacgtccacgaccacactttacatggaactgagcagcctgaggtctgaggacacggccgtgtaCtttttgtgcgagaggcgggaagagtcctcgtcgtgatattatacagggggtgactgttgatgctcttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12067 JY8QFUQ01BN8OF productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 609 96.92 126/130 nt 96.15 125/130 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 X 10 8.X.10 [1.3.31.11] CSNGYGDFPRRW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) gtctggattcaccttcaggagctattggatgagctggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 12068 JY8QFUQ01CV8NL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12069 JY8QFUQ01BYHLS No results 12070 JY8QFUQ01AD2J7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12071 JY8QFUQ01DBBMX unknown (see comment) Homsap IGHV2-5*03 F 186 55.21 106/192 nt 10 7 X 10.7.X [9.17.26.X] null + No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12072 JY8QFUQ01CMOW4 productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12073 JY8QFUQ01BV30U productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-2*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARVRCVTTSCRGLSYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccagcataaagcaagatggaagtgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagtccggtgtgtcaccaccagctgccggggcctctcctactttgactcctggggccagggaaccctggtcaccctctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12074 JY8QFUQ01DNI95 No results 12075 JY8QFUQ01B6VLE productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARVDFYGSSKYKGFDPW in-frame + tctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12076 JY8QFUQ01BUZUI productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tttccggtagttccatcagtagcagtgattactactTggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattacagggggacgcagtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgaggtctgtgaccgccgcagacacggctatgtattactgtgcgagacatcggtcttttggagtgataattgtgaattactttgagacctggggacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12077 JY8QFUQ01CBIYP productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 93.72 209/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 200 to 200 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaacCcgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12078 JY8QFUQ01BFRFB unproductive Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggcccagggaaccctagtcaccgtctcctagcctccaccaaggggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12079 JY8QFUQ01A7WRG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 96.76 209/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12080 JY8QFUQ01BNL2E productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactaTtttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 12081 JY8QFUQ01BWQCK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 603 85.89 140/163 nt 85.28 139/163 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD6-25*01 F 1 8 4 22 8.4.22 [2.2.38.11] CARYQGDTSGYQDVFYAHYGMDVW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (4 AA in JY8QFUQ01BWQCK ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 41 of V-REGION: 56 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) gcctctggattcacgtttaggggctactggatgcactggagatagtacaagttatgcggactccgtgaagggccgcttcaccatctccagagacaacgccaggagcacattgttcctgcaaatgagcagtctgagagtcgaagacacggccatttattactgtgcacggtatcagggcgataccagtggctaccaggacgttttctacgcccactacggtatggacgtctggggccaagggacctcggtcaccgtctattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12082 JY8QFUQ01A0Q4J unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD5-18*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREFRAPSLARYGMDV## out-of-frame - in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagGggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctgggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12083 JY8QFUQ01CJML0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - gcctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12084 JY8QFUQ01AEE83 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 741 83.18 178/214 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AEE83 ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12085 JY8QFUQ01AJFOA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12086 JY8QFUQ01BMO95 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggagccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12087 JY8QFUQ01BVLGG productive (see comment) Homsap IGHV3-7*01 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD5-12*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRERGGFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagaaactattggatgagttgggtccgccaggctccagggaaAggggctggagtgggtggccagtataaAaactagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccggagacaacgccaagaactcactgtatctgcaaatgaaccgcctgagagccgaggacacggctatatatcactgtgtgagagatcgagagaggggcgggttcgacccctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12088 JY8QFUQ01CZYLK No results 12089 JY8QFUQ01AEH4G productive (see comment) Homsap IGHV3-48*01 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.16.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcttcagtttgGagtacttataccatgaactgggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12090 JY8QFUQ01CEH2G No results 12091 JY8QFUQ01BR2B7 No results 12092 JY8QFUQ01CZ28Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca 12093 JY8QFUQ01A08YZ unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12094 JY8QFUQ01ALA99 No results 12095 JY8QFUQ01A4MB9 productive (see comment) Homsap IGHV4-61*07 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); gtctggtggctccgtcagcagtggaaattcctactggacctTggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12096 JY8QFUQ01COFAM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 802 85.39 187/219 nt 84.93 186/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-16*01 F 3 8 8 15 8.8.15 [2.17.38.11] CVKGYFGAFPSAWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'TATAAG' (6 nucleotides at position 16 to 21 in the user submitted sequence), (do not cause frameshift); gcctctggactcaccTATAAGtttgtcaattatgccatgacgtgggtccgccaggctccagggaagggtctggagtgggtctcaggtattaatggtaatggtcgtaatacactgtacgcagacttcgcgaagggccggttcaccatctccagagacaattccaaggacacggtgtatttgcagctgaatagactgggggtcgaagacacggccatgtattactgtgtgaaaggttatttcggggcatttccgtctgcctggttcgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12097 JY8QFUQ01CF2WI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12098 JY8QFUQ01DGPWM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc 12099 JY8QFUQ01DGSKL No results 12100 JY8QFUQ01CRGE6 No results 12101 JY8QFUQ01CATWA productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12102 JY8QFUQ01B8CFK productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12103 JY8QFUQ01BSK1X productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARHEGYNSRYYYFGYW in-frame + tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12104 JY8QFUQ01B4FE6 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame + ctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttc 12105 JY8QFUQ01C37US No results 12106 JY8QFUQ01BZW42 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [2.17.37.11] CAKNNNDFGDYDWF#PW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) tctcctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatatctattatactgggggcaccgactccaaccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgaccctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12107 JY8QFUQ01DXG68 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12108 JY8QFUQ01ASEOA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 830 86.43 191/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctccgggagttcacctttagtagtttctggGatgcactgGggtccgccaagttcCcaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12109 JY8QFUQ01CHO3D unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 412 88.46 92/104 nt 87.5 91/104 nt 8 8 X 8.8.X [1.16.1.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 47 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 12110 JY8QFUQ01C7TMB productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12111 JY8QFUQ01BCU1I unproductive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-8*01 F 2 10 7 X 10.7.X [1.17.38.11] CARGKWGDKPPFYYGMDV## out-of-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12112 JY8QFUQ01ARUTN productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 12113 JY8QFUQ01DJ5EW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaaGggggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12114 JY8QFUQ01AVOE0 No results 12115 JY8QFUQ01C4C3U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12116 JY8QFUQ01CWOR0 unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 259 69.91 79/113 nt 69.03 78/113 nt 8 8 X 8.8.X [0.17.4.X] null - No rearrangement found Low V-REGION identity (69,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); tggatacGaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12117 JY8QFUQ01DHLEX productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 996 95.0 209/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [2.17.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12118 JY8QFUQ01DE0K1 No results 12119 JY8QFUQ01BEZB3 unproductive Homsap IGHV4-61*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARDFRRFLQFSG#YW out-of-frame + ctctggtgactccattagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttcggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12120 JY8QFUQ01B1SQ5 productive Homsap IGHV4-59*03 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatccggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12121 JY8QFUQ01CH38P productive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaAttttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12122 JY8QFUQ01BKLH1 unproductive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAK*LAEQRLVPFLR#W out-of-frame + stop codons cctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaatgattggccgagcagcggctggtcccatttttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12123 JY8QFUQ01AG3LY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12124 JY8QFUQ01CAD0L unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 657 77.88 169/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,88% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcgactatggcatgacctgggtccgccaggctccagggagggggttggagtgggtcgcatctattaatgccggtggtagtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12125 JY8QFUQ01A2EN2 unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 135 77.78 35/45 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found ctctggattcagcctcgccacttatagtatgagttgggtccgcca 12126 JY8QFUQ01CIGYA productive (see comment) Homsap IGHV3-7*01 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) tctctggattcaccttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12127 JY8QFUQ01A5GJK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12128 JY8QFUQ01BUZSL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 797 84.93 186/219 nt 84.47 185/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatncactggggtccgcaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12129 JY8QFUQ01A6ZEV No results 12130 JY8QFUQ01DDN7X productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaggggctagattgggtggcatttatatcatatgatggaagtaatGaggttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12131 JY8QFUQ01C6W6D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDIW in-frame + cctctggattcaccttcagtaactacagaatgaattgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgccaaggggtcactctatctgcacatgagctaccttagagccgaggacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgaaaggtctgcttttgatatctggggccaagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttccc 12132 JY8QFUQ01B7KC5 No results 12133 JY8QFUQ01AUWE8 productive (see comment) Homsap IGHV3-7*01 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggTagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 12134 JY8QFUQ01B98IB No results 12135 JY8QFUQ01C2J66 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 10 7 11 10.7.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12136 JY8QFUQ01AP5RM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 392 76.47 104/136 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (76,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 12137 JY8QFUQ01BLAAL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 826 87.79 187/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [X.17.38.11] CIMDLVGRADYW in-frame + ggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgcctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12138 JY8QFUQ01C4PF5 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 953 91.96 206/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaagggactggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12139 JY8QFUQ01DW3PR productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12140 JY8QFUQ01CVG3H productive Homsap IGHV3-66*02 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame - gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12141 JY8QFUQ01BQ72X productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12142 JY8QFUQ01A60V7 productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12143 JY8QFUQ01BNVHC unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12144 JY8QFUQ01AG8B1 No results 12145 JY8QFUQ01CIC1B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'T' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgaTcgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12146 JY8QFUQ01BVJJA productive Homsap IGHV4-4*07 F 953 93.95 202/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt 8 7 9 8.7.9 [1.17.38.11] CARGDWYFDLW in-frame - tctctggtggctccatcattaatcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtagtcataccagtggaagcaccaggtacaacccctccctcaagagtcgagtcaccgtgtcagcagacacgtccaagaaccagttctccctgaagcttagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggagactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12147 JY8QFUQ01AQ8YC productive (see comment) Homsap IGHV3-11*01 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-7*01 F 1 8 8 15 8.8.15 [1.17.38.11] CVRESRSWTGSTLPAYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'T' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgactattacatgagttggtaccgccaggctccaggtcaggggctggagtggctttcatatataagtcaaactggcaaaaccacatacttcgcagactctgtgaagggccgattcaccatctccagggacaatgccaagacatcagtgtttctgcaaatgaacagcctgagagttTgacgacacggccgtgtatttttgtgtgagagaatctaggagttggactggaagtacacttccagcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12148 JY8QFUQ01CIG7Q No results 12149 JY8QFUQ01BRXXD unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 110 53.24 74/139 nt 10 7 X 10.7.X [1.17.11.X] null + No rearrangement found stop codons tctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12150 JY8QFUQ01BXZRW productive Homsap IGHV3-48*02 F 828 87.1 189/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRYSYAHGMDVW in-frame + ctccggattcacctccatctcctatggcatgcactgggtccgccagattccaggaaaggggctggagtcggttgcatacattagtgatagtaatagcagcatatactatgcagactctgtgaagggccgattcaccatctcccgagacaaagacaagaagtcagtatatctgcaaatgagcagcctgagagacgaggacacggctatttattactgtgcgagggggcgatacagttatgctcacggaatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12151 JY8QFUQ01A6UFN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 7 8 11 7.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) cctctggatcacttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12152 JY8QFUQ01C98OS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 587 78.24 151/193 nt 8 8 X 8.8.X [1.17.30.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaact 12153 JY8QFUQ01CNKPH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 782 85.12 183/215 nt 84.19 181/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactagagtggattggatttGctttcttacagtgggcccaccaactacaGacccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12154 JY8QFUQ01ADDVJ productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag 12155 JY8QFUQ01CYW4W productive (see comment) Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD2-21*01 F 2 7 8 9 7.8.9 [1.17.38.11] CVRDNYSVDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaattactgatgcagtgggtccgccaagctccagggaaggggctggagtgggtctcacatattaccagtgatggaagcaccacaacttacgcggactccgtgaagggccgattcaccacctccagagacaacggcaggaacaccctttatctgcaaatgaacagcctgagagccgaggacacggctacatattactgtgtaagagacaactattccgttgatgtctggggccaggggacaatggtcaccgtctccacagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12156 JY8QFUQ01B06BT productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12157 JY8QFUQ01ANCM4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12158 JY8QFUQ01ASQ57 No results 12159 JY8QFUQ01C8154 productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12160 JY8QFUQ01ACCK5 No results 12161 JY8QFUQ01AVH3D No results 12162 JY8QFUQ01B1595 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12163 JY8QFUQ01CE5RG productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [2.17.38.11] CARADYYDTSAYYLDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 60 of V-REGION: 9 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) gcctctgggtacagcttgcgaggctctgttttgcactgggtccgccaggcttccgggaaaggactggagtgggttggccgtgtcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggcttatctggaaatgaacagcctgaaaaccgaggacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctggggccaggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12164 JY8QFUQ01DK3A2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAARIDSGHYWNAFDIW in-frame - tctggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12165 JY8QFUQ01C6C7H No results 12166 JY8QFUQ01BD3IS productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagga 12167 JY8QFUQ01ARIKI No results 12168 JY8QFUQ01CNGNP productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12169 JY8QFUQ01DBO7O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12170 JY8QFUQ01CLSK9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggGggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 12171 JY8QFUQ01CRM77 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12172 JY8QFUQ01CXXEM No results 12173 JY8QFUQ01DPB0D unproductive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 976 94.91 205/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGDLTGGSVLL*Q*WFK#YW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); tctagattcaGccttcagtagctataatatgcactgggtccgccaggctccaggcaaAggggctagagtAgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12174 JY8QFUQ01BBMWB unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found tgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 12175 JY8QFUQ01CZFLE productive Homsap IGHV3-66*02 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame - gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12176 JY8QFUQ01BGTTQ productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame - tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12177 JY8QFUQ01AU3KK No results 12178 JY8QFUQ01DCIJS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12179 JY8QFUQ01AW82K productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctgaagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12180 JY8QFUQ01ANCOI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12181 JY8QFUQ01BPYKB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 863 89.3 192/215 nt 87.44 188/215 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [0.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'AATG' (4 nucleotides at position 85 to 88 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); ctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaTggggctggagtgggtctcaactattactAATGgtgggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctCccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttaGtttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12182 JY8QFUQ01CFWQ8 productive Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARYRGSYYDYGGVDVW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12183 JY8QFUQ01BWU1H unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 41 90.0 9/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctcaggatt 12184 JY8QFUQ01B9W7D unproductive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 878 89.45 195/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [1.17.38.11] CARDKDVTARGTFDM## out-of-frame + tctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggaacagtggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 12185 JY8QFUQ01BWFLL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARDGRGGDLDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12186 JY8QFUQ01DTXRK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKQTIFDYYYYGLDVW in-frame - gcctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatagacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12187 JY8QFUQ01BFWP5 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame - ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggagggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12188 JY8QFUQ01DCMLJ productive Homsap IGHV3-30*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame - ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttacttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12189 JY8QFUQ01DA17U productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12190 JY8QFUQ01DG6A9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); ttccgggggttcaccgtcagtagccaagTacatgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12191 JY8QFUQ01AB5OR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12192 JY8QFUQ01ACI6J No results 12193 JY8QFUQ01BWMBN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12194 JY8QFUQ01BMBTQ No results 12195 JY8QFUQ01C4VXF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12196 JY8QFUQ01CHIJT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12197 JY8QFUQ01B7P7N productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 791 85.58 184/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [0.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12198 JY8QFUQ01BO2V4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + cctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12199 JY8QFUQ01CTSF9 No results 12200 JY8QFUQ01DE1Y0 productive Homsap IGHV3-48*01 F 928 91.78 201/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CTRQTGNYYYFGVDVW in-frame - gcctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12201 JY8QFUQ01CVH72 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 463 68.06 147/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12202 JY8QFUQ01CTPB4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12203 JY8QFUQ01CHH44 No results 12204 JY8QFUQ01CGOF5 productive (see comment) Homsap IGHV4-55*03 P (see comment) 733 82.33 177/215 nt 80.93 174/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.16.38.11] CARDQSVYTAGSYFDSW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactgaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaTccaattctcCcctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12205 JY8QFUQ01A2XE9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12206 JY8QFUQ01BSGCG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-7*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKVFQVPGEHHFYYFGMNVW in-frame - cctctggattcatgtttaggaactatgccatgagttgggtccgccaggctccagggagggggctggagtgggtctcaactattagcaataatggaagccacacatactacgcagactccgtcaagggccggttcaccatctccagagacaattccaagaacacggtgtatatgcagatgaacaggctgagagtcgaggagacggccctgtactactgtgcgaaagtcttccaggtgcctggcgagcaccacttctactacttcggaatgaatgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12207 JY8QFUQ01B24MT productive (see comment) Homsap IGHV3-9*01 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [2.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccCctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12208 JY8QFUQ01AFQKU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTTRRGTYATFYW in-frame - cctctggattcactttcagtgacgcctggatgaggtgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaagactgatggtggaacaacagactacgctgcgcccgtgcaaggcagattcaccatctcaagagatgattctaagaacacactatatttgcaaatggacaacctgaaaaccgaggacacagccgtgtattactgtaccacacgacgtgggacttatgctacattctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12209 JY8QFUQ01B38BV productive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcCccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12210 JY8QFUQ01CGBHU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctcaggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcaggc 12211 JY8QFUQ01CCB9O unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 644 77.06 168/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12212 JY8QFUQ01C1CD6 No results 12213 JY8QFUQ01BWB0K unproductive Homsap IGHV3-9*02 F 901 90.41 198/219 nt Homsap IGHJ6*04 F (see comment) 83 60.34 35/58 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [2.17.38.11] CGKDMRPGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccagggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12214 JY8QFUQ01CT9HA productive (see comment) Homsap IGHV1-18*01 F 817 87.32 186/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-16*01 F 2 8 8 24 8.8.24 [0.16.38.11] CARDGYCSTKNCFAKTDFVWGTINYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 207 to 207 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) tggttacagcttttaccaatatggtattagctgggcgcgacaggcccctggacaagggcttgagtggatggatggatcagcacattcaatgatgtcacataccttgcacagaagttccagggcagagtcaccatgaccactgacacctccacgagcacagcctacttggaactaaggagcctgacatctgacgacacggccgtttaCtttttgtgcgagagacggatattgtagtacgaagaattgcttcgccaagaccgacttcgtttgggggaccataaactactggggccagggatccctggtcgccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12215 JY8QFUQ01C73E8 No results 12216 JY8QFUQ01DDY3T No results 12217 JY8QFUQ01BDULP No results 12218 JY8QFUQ01B3IOP productive Homsap IGHV3-72*01 F 894 89.24 199/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGYDYW in-frame + ctctggcttcatcttcagtgaccactatatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagagttgcatctaacacttacgccacagaatacgccgcgtctttcaaaggcagattcgtcatctcaagagacaattcaaggaactcattgtttctccaaatgaacagcctgaaaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctatgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12219 JY8QFUQ01DKCLG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 687 80.37 172/214 nt 79.91 171/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccaCggcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12220 JY8QFUQ01DCGRP productive (see comment) Homsap IGHV3-30*01 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-16*01 F 3 7 8 15 7.8.15 [2.17.38.11] CARVITAYYYYYAMEVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) gactctggatcaccttcaatagcgttactatgcactgggtccgccaggctccaggcaaggggctagagtgggtggctattatatcatatgatggaagtaagacagactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagagaacgctgtttctgcagatgaacagcctgagagttgaggacacggctgtgtattactgtgcgagagtgattaccgcttactactactactacgctatggaggtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12221 JY8QFUQ01C1C90 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 838 87.21 191/219 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARLRSFGDYPLDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 12222 JY8QFUQ01CSDXL unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1066 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - stop codons tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtagtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12223 JY8QFUQ01CN2LN unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt 99.07 212/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacCccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctcCcctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 12224 JY8QFUQ01A2U3J unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 358 86.32 82/95 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found cctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 12225 JY8QFUQ01BX0V8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'CCTT' (4 nucleotides at position 22 to 25 in the user submitted sequence), (cause frameshift); tctggattcaacctcaatagcCCTTttgggcatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12226 JY8QFUQ01BHPPA productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 992 95.79 205/214 nt 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagGctactatatacactgGggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggnggtgccaCcaagntacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12227 JY8QFUQ01ANX39 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKSPDSGYDSNWLDPW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaacttggcgaagttcgccatgagctgggtccgccaggctcctgggaaggggctggagtgggtctcagagatcagtggctccggtagtaaagtcggatatgcggagtccgtgaagggccgattcaccatctccaaagacaattccaagaacacattgtacttgcaaatgaccgacctgagacccggcgacacggccatttattactgtgcgaaaagtcctgatagtggctacgattctaactggctcgacccctggggcctgggaaccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12228 JY8QFUQ01A5D4P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVPHQNIIYLDYW in-frame - tctggattcgactttagcagcgcttccatggcctgggtccgccaggctccagggaaggggctggagtggatctcagctgtcagtggacgtggtgacaacaccttctacgcagcctccgtgaagggccggttcaccatctccagagaccattccaagaacacgctgtggcttcaaatgaacaacctgagagccgaagacacggccctatattactgtgcgagggaagtcccacatcaaaatataatctaccttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12229 JY8QFUQ01ACXPV productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame - tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12230 JY8QFUQ01AAQO2 No results 12231 JY8QFUQ01CJGTX No results 12232 JY8QFUQ01A0931 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12233 JY8QFUQ01AD002 No results 12234 JY8QFUQ01AX0VD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 12235 JY8QFUQ01BY72S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - cctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12236 JY8QFUQ01AUPMO unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [2.16.38.11] CARDTLEVVSNMDDAFDF## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 41 to 42 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtcgttatagcatgaactgggGTccggccaggctccagggaagggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctgggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12237 JY8QFUQ01ATTMO productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtgacggtgtccgtggaactcaggc 12238 JY8QFUQ01B9G18 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 119 54.62 71/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12239 JY8QFUQ01AMXFZ No results 12240 JY8QFUQ01C7W4Y No results 12241 JY8QFUQ01DC5GC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 85.98 184/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.37.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12242 JY8QFUQ01BW28C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaanttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12243 JY8QFUQ01C1AQG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12244 JY8QFUQ01A7MBK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagatactGggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12245 JY8QFUQ01AWSIU productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag 12246 JY8QFUQ01A7M44 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12247 JY8QFUQ01CUTTR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12248 JY8QFUQ01BEYEJ productive Homsap IGHV3-72*01 F 926 90.62 203/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12249 JY8QFUQ01AJGDO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12250 JY8QFUQ01CDEVZ No results 12251 JY8QFUQ01AQMC4 unproductive (see comment) Homsap IGHV3-49*02 F (see comment) 599 73.57 167/227 nt 73.13 166/227 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 1 8 10 9 8.10.9 [2.17.38.11] CAGLLSHFDIW in-frame - stop codons Low V-REGION identity (73,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); attgatgtggtcgggcttcggggcttacacgaatgacttggttccgcttgcctccagggaggggcctggGaattggtaggtttcatcaggagcacgggaaacggtgggacaacagagtacgccgcgtctgtgagaggcagagtcttcatctcaagagatagatccaacaatgtcgcctatctacaaatgaacaatctgaagaccgaggacaccgccatatattattgcgctggactcctttcccattttgacatatggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtctccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12252 JY8QFUQ01B9US6 unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 264 72.38 76/105 nt 8 7 X 8.7.X [1.17.1.X] null + No rearrangement found Low V-REGION identity (72,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttccccca 12253 JY8QFUQ01CXO7E productive (see comment) Homsap IGHV3-66*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [2.17.38.11] CVGDRQRDNYFAYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gcctctggactcaccttcagtggccCagtacttagactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcaacacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12254 JY8QFUQ01DBCAP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAHGPSAAPHYYYYYGLEAW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatgGgcatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagatattagcgctggtggcgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaatttcaggaacacgctgtatctgcaaatgagcagcctgagagccgaggacacggccctttattactgtgcgcatgggcccagtgcagcaccccattactactactattacggtttggaagcttggggccaagggaccaaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12255 JY8QFUQ01BH7NG productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame + ctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctggtccagggcttcttccc 12256 JY8QFUQ01BXSH4 No results 12257 JY8QFUQ01DNBGA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 861 88.18 194/220 nt 86.82 191/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 41 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) aggcctcctggattcaccCTttgggttattatggcatggactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12258 JY8QFUQ01A0OMH productive (see comment) Homsap IGHV3-74*03 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); ctctggattcacGtttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctcgcctggtccagggcttcttccccca 12259 JY8QFUQ01BVD0A productive (see comment) Homsap IGHV3-33*03 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtGgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12260 JY8QFUQ01BIEKD productive Homsap IGHV3-43*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame + ctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggctcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12261 JY8QFUQ01APYPD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggattcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12262 JY8QFUQ01DRI0O unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 41 90.0 9/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctccggatt 12263 JY8QFUQ01BJ66M productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctagattcacctttaatggttactggatgagttgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12264 JY8QFUQ01A0VIE productive (see comment) Homsap IGHV3-30*01 F 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'CA' (2 nucleotides at position 99 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 156 to 156 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtCAaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcCccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12265 JY8QFUQ01AIK4Y productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12266 JY8QFUQ01CNFRH productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggctacttccccgaaccggtgacggtgtcgtggaactcag 12267 JY8QFUQ01DGWBL productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [2.17.38.11] CARGGGGKSIPLDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); gcgtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttaAtttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12268 JY8QFUQ01AULL8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGSYRLQLESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagctatggcatgagttgggtccgccagtctccaaataagggactggagtgggtcgcaggcattagtgcaaatggtggcagtataaattatctggacgccgtgaagggccggtttatcatctctagagacaattccaagaacacgttgtatctgcaaatggacagcctgacagtcgaggacacggccgtttattactgtgtgaaagatcgtgattttctttgggggagctatcgtcttcaacttgaatcttggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12269 JY8QFUQ01CZT5A unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 704 81.6 173/212 nt 81.13 172/212 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD1-7*01 F 2 8 7 X 8.7.X [1.17.37.11] CARLDGHFDL# out-of-frame + Low V-REGION identity (81,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctgggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12270 JY8QFUQ01A3I1V productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*08 F 782 93.3 167/179 nt 92.74 166/179 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 X 7 18 X.7.18 [X.14.38.11] CARGWAQQAGATFVGWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'TTGG' (4 nucleotides at position 39 to 42 in the user submitted sequence), (cause frameshift); ggatccgccagcccccagggaaggggctggagtggcatTTGGgggaaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12271 JY8QFUQ01B3P0G productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.16.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccacctccgccatggcctgggtccgccaggtccagggaaggggctggagtgggtctcaactattagacctagtagtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12272 JY8QFUQ01CFR5M productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12273 JY8QFUQ01BU31Q productive (see comment) Homsap IGHV3-9*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaaggGgcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12274 JY8QFUQ01AYEC2 No results 12275 JY8QFUQ01A6R0X productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaGggggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12276 JY8QFUQ01DEFGF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12277 JY8QFUQ01CY2LK No results 12278 JY8QFUQ01B6KZL unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 839 86.43 191/221 nt 85.97 190/221 nt 8 10 X 8.10.X [1.17.37.X] null + No rearrangement found in FR3-IMGT, from codon 94 of V-REGION: 2 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag 12279 JY8QFUQ01BUAG1 No results 12280 JY8QFUQ01DP3B2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12281 JY8QFUQ01ACRP3 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 12282 JY8QFUQ01BHE62 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12283 JY8QFUQ01ANKL9 No results 12284 JY8QFUQ01CCTG1 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 922 90.22 203/225 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 1 8 10 X 8.10.X [2.17.38.11] CATDRPYYKTLLADS#YYYGMDVW out-of-frame - tgctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12285 JY8QFUQ01AXXI5 No results 12286 JY8QFUQ01B6FTY No results 12287 JY8QFUQ01CXMEU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12288 JY8QFUQ01AVBAG productive (see comment) Homsap IGHV3-48*01 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [0.17.37.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 174 in the user submitted sequence), (cause frameshift) ctggattcaccctcagtagcaacagcatgaactgggtccgccagactccggggcaggggctggagtgggttgcacacattagtagtagcagcgataccatatactacgcagactctgtggggggccgattcaccatctccagagacaatgccaagaactcactgcatctgcaatgaacagtctgaGgagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 12289 JY8QFUQ01ATA9W productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.57 187/216 nt 84.72 183/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggCttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctnaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12290 JY8QFUQ01AGVPX productive (see comment) Homsap IGHV4-4*07 F 827 87.44 188/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'CC' (2 nucleotides at position 84 to 85 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtcCCaaaaccagtgggaCccccccactacaaacccttcctcaagagtcgaatcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccatttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12291 JY8QFUQ01B66RM productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 824 86.7 189/218 nt 85.78 187/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-10*02 F 2 8 7 14 8.7.14 [2.17.38.11] CVGEGGGRGVSAFEFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); atacccctgagttcaccgtcagGttacaactgcctaagctggatccgccaggctccagggaagggcctagagtgggtctcagAttttttgtagcgctaatggaccatactacgcagactccgtgaagggccgattcaccaccgccagagacaatagtaagaacatactgtatcttcaaatgaacagcctgagagccgaggacacggccgtgtactactgtgtgggcgaaggtggtggtcgtggagtgagtgcttttgagttctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12292 JY8QFUQ01A17DH unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 103 52.99 71/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12293 JY8QFUQ01CW1RS No results 12294 JY8QFUQ01CXZPX unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaaggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 12295 JY8QFUQ01CIAL0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12296 JY8QFUQ01CRM51 productive (see comment) Homsap IGHV4-59*03 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.37.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) gtctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccCaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12297 JY8QFUQ01AJ4K5 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CATAYYYDNRGHYQEDPFDYW in-frame + ctctggattcacctttagtagccattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaactgcggtattttatgtggagtctgtgaagggccgattcaccatctccagagacaatgtcaggggctcacttcatctgcaaatgaatggcctgagagccgaggacacggctgtatattactgtgcgacagcttattactatgataatagaggtcattaccaagaggatccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12298 JY8QFUQ01CCSBL productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame + tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtctcgcctgcctggtccagggcttcttcccccag 12299 JY8QFUQ01CYDEI unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [2.17.38.11] CARKRVPGGTFLW#DYW out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggGggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggacctttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12300 JY8QFUQ01BCS5Q productive (see comment) Homsap IGHV4-4*07 F 872 89.77 193/215 nt 87.91 189/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARFSSYGDTFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); tctctgatgggtccatcggaagttactactggacttggatccggcagcccgccgggaaggcaatggagtCggatcgggcgtgtctttagaactCgggaacacgaattacaAacccctccctcaagagtcgggtcaccatgtcagttgacacgtccaagaatcaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgAttttactgtgcgagattctcgtcctacggtgacacctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12301 JY8QFUQ01DF8ZC productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12302 JY8QFUQ01BHGJG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 7 8 14 7.8.14 [2.17.38.11] CAREVPHQNIIYLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) cctgctggattcgacttagcagcgcttccatggcctgggtccgccaggctccagggaaAGggggctggagtggatctcagctgtcagtggacgtggtgacaacaccttctacgcagcctccgtgaagggccggttcaccatctccagagaccattccaagaacacgctgtggcttcaaatgaacaacctgagagccgaagacacggccctatattactgtgcgagggaagtcccacatcaaaatataatctaccttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 12303 JY8QFUQ01CBD1A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12304 JY8QFUQ01AQ5S2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.16.38.11] CAKDQSCIVGPC#FDYW out-of-frame - in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 43 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tccgaattcatccttgacagttatgccatgagttgggtccgcaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12305 JY8QFUQ01BBSNW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12306 JY8QFUQ01DW9X4 No results 12307 JY8QFUQ01DM0QJ unproductive Homsap IGHV3-48*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.16.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccaggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12308 JY8QFUQ01C3WRL productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 84.62 187/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12309 JY8QFUQ01BP7V3 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12310 JY8QFUQ01B8NNC No results 12311 JY8QFUQ01AYVUG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12312 JY8QFUQ01AGNO8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDI* out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctagggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12313 JY8QFUQ01AVQGZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggattcacCctttggttattatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12314 JY8QFUQ01DGVV1 productive (see comment) Homsap IGHV3-7*01 F 1014 95.91 211/220 nt 95.45 210/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); aggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12315 JY8QFUQ01BSAA3 No results 12316 JY8QFUQ01BVDC3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 651 77.13 172/223 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-10*01 F 3 10 7 20 10.7.20 [2.17.38.11] CATSTTRVRGAIRNLVTWFDPW in-frame - Low V-REGION identity (77,13% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctcgggtgtctccacaaccagtcaatttaacttctgggtctggatccgccagcctccagggaaggcaccggagtggatagccagttcacgttatggagggaagacgttttacaatccgtcgctcgagagtcgggtcaacatgtctctgggcacgtctaagaatcagttttacctgaacctgatgtctgtgaccgccgcagacacggctgtttatttctgtgcgacgagcaccactcgagttcggggagccatcaggaaccttgttacctggttcgacccctggggcccgggaactcgagtgactgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12317 JY8QFUQ01DFMAZ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CASLNTHAGPGSRRS#FDIW out-of-frame + ctctggattcaccttcagtaactacagaatgaattgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgccaaggggtcactctatctgcacatgagctaccttagagccgaggacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggcagccgaaggtctgctttgatatctggggccaagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccc 12318 JY8QFUQ01CQO2O productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctAgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12319 JY8QFUQ01ASOW0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAFSRALTGKWIDYLDHW in-frame + tggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 12320 JY8QFUQ01C3RLJ productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12321 JY8QFUQ01AY1CS No results 12322 JY8QFUQ01BV8LF productive (see comment) Homsap IGHV3-7*03 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) cccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12323 JY8QFUQ01DG4MA No results 12324 JY8QFUQ01AOJOM unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYE#DYW out-of-frame - in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 190 to 190 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagaGgacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacatgcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12325 JY8QFUQ01CTG21 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 255 57.48 123/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found Low V-REGION identity (57,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12326 JY8QFUQ01BNHUN productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttgcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12327 JY8QFUQ01AK5BM productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtccttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12328 JY8QFUQ01B8W39 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 704 81.6 173/212 nt 81.13 172/212 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12329 JY8QFUQ01DO2BI No results 12330 JY8QFUQ01B6ZEZ unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 805 100.0 162/162 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 X 7 X X.7.X [X.9.38.11] CARSRTFYGSANY## out-of-frame - gggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12331 JY8QFUQ01CMK7J unproductive (see comment) Homsap IGHV1-2*02 F 804 86.45 185/214 nt 85.98 184/214 nt Homsap IGHJ3*02 F 182 84.0 42/50 nt Homsap IGHD3-16*02 F 2 8 8 X 8.8.X [0.17.38.11] CARHFS*HQRRL#DFDIW out-of-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tggatacagcttcaccgactTtttacattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaaatggtggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggagatgagcaggctgagatctgacgacacggccatttattactgtgcgagacatttttcgtgacaccaacgacgtctgtgattttgatatctggggccaggggacaaaggtcaccgtctntttagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtcagggcttcttccc 12332 JY8QFUQ01BKZBL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.16.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12333 JY8QFUQ01B0BMU productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 750 82.06 183/223 nt 81.17 181/223 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); atttccgggtagttccatcagtagcagtgattactactggggctgggtccgccagtccccagggaagggtctggagtggattggCaagtgtctattacaggggggacgcAgtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgagctctgtgatcgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12334 JY8QFUQ01CWXBJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12335 JY8QFUQ01CUILV No results 12336 JY8QFUQ01BCD74 productive (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 671 78.9 172/218 nt 78.44 171/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARVTSDRYFYYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); gctctggattcagtataagtgacgattatatgagttgggtccgccaggctccaggcaaggggctggcttGgggtatcatacatcagtgccagtggcgagacgatagactacgcagactctgtgaggggccgattcgccatctccagggacagcgctgagaattcactctatttggagatgaacagtctaacagacgaagattccggaatgtattattgtgcgagagtgacgtcggaccgctacttctattacggaatggacgtctggggccaggggaccactgtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12337 JY8QFUQ01DLNQ2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12338 JY8QFUQ01A3DG1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcacgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12339 JY8QFUQ01CQY9U unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 108 53.33 72/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12340 JY8QFUQ01CYB7H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcttggaactca 12341 JY8QFUQ01CS823 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12342 JY8QFUQ01AXK7W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 523 89.92 116/129 nt 88.37 114/129 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 X 12 8.X.12 [1.3.31.11] CVKDISRSGCFEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 37 in the user submitted sequence), (do not cause frameshift) tctggattccagtttagcaactatgccatgagctggggccgggtcaccaGtctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12343 JY8QFUQ01A3HM7 No results 12344 JY8QFUQ01CHOYS No results 12345 JY8QFUQ01CXUFF productive (see comment) Homsap IGHV4-39*02 F (see comment) 699 80.0 176/220 nt 79.09 174/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 10 7 15 10.7.15 [1.16.38.11] CAIHNYYGSGRNYFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctggagtctccgccatcggcaccagttccttctAggggctgggtccgccagcccccagggaagggctggagtggatcggagctgttcattacagtggaagtatctcttacatgccggccctcaagagtcgactcaccatgtccttagacacgtcaaaaggtcacttgtccctgagactgacctcagtgacctccgcagacacggctatgtactactgtgccatacacaactactatggatcggggagaaactactttgaccactggggacagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12346 JY8QFUQ01B2F6Z unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGS# out-of-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtgggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccggctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12347 JY8QFUQ01B33G0 No results 12348 JY8QFUQ01AF3QZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12349 JY8QFUQ01DI3MQ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARRGRCG*LLVLRSL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctagtgactccatcagcagtactaattactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctgggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 12350 JY8QFUQ01BH6WY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca 12351 JY8QFUQ01AGH15 No results 12352 JY8QFUQ01BTE0F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12353 JY8QFUQ01BZ3C1 No results 12354 JY8QFUQ01DGZL8 productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame - ctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12355 JY8QFUQ01AEZL4 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 836 87.91 189/215 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASLVTINDNGDYTWAFDVW in-frame + tggatggtgggtccttcagtaataagtattggagttggattcgccagttcccagggaaggggctagagtggattggagaaatcaaccaaagtggaagcaccaactacaatccgtccctcatgagtcgagtcaccatctccatagacacgtccaagatgcagttctccctgaagttgacctctgtgaccgccgcggacacggctgtctattattgtgcgagtttagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctgggcccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 12356 JY8QFUQ01B9ZOB unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 923 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASDLGGQKSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12357 JY8QFUQ01C2BC0 No results 12358 JY8QFUQ01B4F0J No results 12359 JY8QFUQ01CYNV8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 866 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [3.16.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) aggcctcctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaatgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12360 JY8QFUQ01BZKKR No results 12361 JY8QFUQ01BK9SP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 1 10 7 12 10.7.12 [1.17.38.11] CAWGWFGLNYFDYW in-frame - tctctggtggctccgtcagaagtaccagttactactggggctggatccgccagcccccagggaaggggctggagtggattagtaacattcattctagtggaaccacctactacaacccgtccctcaacagtcgagtcaccatgtccgtaaacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggctgtatattactgtgcatgggggtggttcggactgaactactttgactactggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12362 JY8QFUQ01COABY unproductive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARNTNYGGNSGDYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccaagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12363 JY8QFUQ01AQMNE productive (see comment) Homsap IGHV3-66*02 F 907 92.02 196/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttggtccgccagctccaggaaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12364 JY8QFUQ01CWRHM unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 739 91.91 159/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgc 12365 JY8QFUQ01BSWUC productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12366 JY8QFUQ01DFMZ6 productive (see comment) Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARGKAGHTHYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); gcctctgcattcaccttcagtagttatgctatgcactgggtccgccaGggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggGggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12367 JY8QFUQ01BZU3Z productive (see comment) Homsap IGHV3-48*01 F 1030 97.24 211/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.37.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'TC' (2 nucleotides at position 78 to 79 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctGatagcatgaactgggtccgGccaggctccaggggaagggctggagtgggtttTCatgacattantagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12368 JY8QFUQ01B8W6T No results 12369 JY8QFUQ01BLVMS No results 12370 JY8QFUQ01DW7YL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 734 81.65 178/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12371 JY8QFUQ01ABKHV No results 12372 JY8QFUQ01CDYFH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12373 JY8QFUQ01AHFVU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ3*02 F 250 100.0 50/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame + tctggattcacctttagcagctatgccatgggctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtgggagtggtcggagcacatactacgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccatatattattgtgtgaaaaggttggaaggagtggctgatgatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 12374 JY8QFUQ01DBVBN No results 12375 JY8QFUQ01DSBEO productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12376 JY8QFUQ01DPT8R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12377 JY8QFUQ01DTVEM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1011 95.07 212/223 nt 94.17 210/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [3.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR1-IMGT at codon 26 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 183 in the user submitted sequence), (cause frameshift) tggcagcctGctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12378 JY8QFUQ01AX93I productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame + ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 12379 JY8QFUQ01A3BLN productive (see comment) Homsap IGHV3-30*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 7 8 14 7.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) cctcggattcacctcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12380 JY8QFUQ01BS0FQ unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRRGLNYYSFMDVW# out-of-frame + ctctggatacagcttcgccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcgatcctagtgactctgataccagatatagcccgtccttccaaggccaagtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgcaggcctcggacaccgccacgtattactgtgcgagacggcggggccttaactactactcctttatggacgtctgggggccaagggacccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12381 JY8QFUQ01AUM5Q productive (see comment) Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagtaattactggtggatttGgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgaatcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 12382 JY8QFUQ01DJLBK productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccta 12383 JY8QFUQ01BEBN4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + tctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12384 JY8QFUQ01CABVX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt 90.5 200/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgataatttctactGggggctggatccgccagCcccccagggaaggggActgcagtggattgGggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12385 JY8QFUQ01BGQMX productive (see comment) Homsap IGHV4-39*03 F 893 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 72 to 74 in the user submitted sequence), (do not cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12386 JY8QFUQ01CSRA0 productive (see comment) Homsap IGHV3-66*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-18*01 F 3 8 7 10 8.7.10 [2.16.38.11] CARDRYNSATLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) ggctcaagactaatcgccactagtaactatatgagttgggtccgccaggctccagggaagggctgcagtgggtctcagttatttataacggtggtagaacatactacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacggtgcatcttcaaatgaacagcctgagaactgaggacacggctgtgtactactgtgcgagagatcgatacaactctgccacgctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12387 JY8QFUQ01AKD2L productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'A' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctctggattctccAtttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12388 JY8QFUQ01AVLTJ No results 12389 JY8QFUQ01AS6VB unproductive Homsap IGHV3-48*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [0.17.38.11] CARAGWELLQG#DYW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); ctggattcaCcctttagcagtcgtagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattgatggtggtagcactaccatattctacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatctgcaaatggacagcctgagagccgacgactcggctacatattactgtgcgagagcgggttgggaattactacaagggatgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12390 JY8QFUQ01BXLCN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12391 JY8QFUQ01A9XMX productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1065 97.76 218/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 15 8.10.15 [1.17.38.11] CTTFGLTTVTKGYFDFW in-frame + ctctggattcactttcaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaacagagtacgctgcacccgtgaaaggcagatttaccatctcaagagatgattcaaaaaacacgctttatctgcaaatgaacagcctgaaaatcgaggacacagccgtgtattactgtaccacattcggcctgactacggtgactaaaggctactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12392 JY8QFUQ01A7LR6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 825 86.36 190/220 nt 85.91 189/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [2.17.38.11] CVKDRDFLWGTYRLQLE##W out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); agcctctggattcatgtttagtgactatTgggatgagctgggtccgccaagttccacaagaggggctggagtgggtcgcaggtatcagtggcagtggtggaagcattaactacgcagactccgtgaagggccgattcaccatttccagagacaattccaagaacactctctatttgcaaatgaccgacctgagagccgacgacacggccgtatattactgtgtgaaggatcgtgacttcctttgggggacttatcgtcttcaacttgaaaaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12393 JY8QFUQ01C44LZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 106 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12394 JY8QFUQ01BQ58O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12395 JY8QFUQ01C30TT No results 12396 JY8QFUQ01A699S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame + cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12397 JY8QFUQ01CL1G6 No results 12398 JY8QFUQ01DVSSC unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 X 7.8.X [1.17.38.11] CAKGTRL*RLVYI#DSW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaatgggccggagtgggtctcagCcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaagggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12399 JY8QFUQ01AXKC5 unproductive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRGGSAYPIFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactgggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12400 JY8QFUQ01CO56R No results 12401 JY8QFUQ01BNLQK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggcaactc 12402 JY8QFUQ01CA9YP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [2.16.38.11] CAKDRITIFPTTGST#W out-of-frame - in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagcagctatgccatgagctgggtccGgccaggctccagggaagggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatatttcctacaactggttcgacccctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12403 JY8QFUQ01AEF8J productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFDNW in-frame + cccctggattcaccttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtgataaatactatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatgaacagcctgagaagtgaagacacggctgactattactgtgcgaaagacccatttatagcagcaactggccgcccctggtattttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12404 JY8QFUQ01AZW8J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARALIVVAGAPVYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tctctggattcaccttcagtagttatagtatgatctgggtccgccaggctGccagggaaggggctggagtgggtcgcttcaattagtcataccgggggttccaaatattacggagactcactgaagggccgattcgccatctcaagagacaacgacaagaactcactgtatctgcaaatgaccagcctgagagccgaggacacggctgtctactactgtgcgagagccctaatagtagtggctggtgcccctgtctattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12405 JY8QFUQ01A4L5L unproductive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPFTVTTGKDAY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcgagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12406 JY8QFUQ01AY12P No results 12407 JY8QFUQ01BY4NA productive (see comment) Homsap IGHV3-48*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARESWWSGFYGWYDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgagggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12408 JY8QFUQ01AJIEM productive Homsap IGHV3-48*03 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDRADLFYDSSGYQFDLW in-frame - ctctggattcatcttcagcgatcatggaataaactgggtccgccaggctccggggaagggtctggagtggatttcattcgtcagtagtaggggtgggaccatccactacgcagactctgtgaagggccgattcatcatctccagagacaactccaggaacacagtatttctacaactgaacagactgagagacgaagacacggctatttattattgtgcgagagacagggcggatttgttctatgatagcagtggttaccaatttgatctttggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12409 JY8QFUQ01B12IK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12410 JY8QFUQ01AUNQO unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CATLRGGY#FDYW out-of-frame - ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12411 JY8QFUQ01BJAW9 productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcagg 12412 JY8QFUQ01BZIFS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 863 88.84 191/215 nt 85.58 184/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 8 7 16 8.7.16 [1.17.38.11] CTNDHSMAVSAKHAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'AGTGCA' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 120 to 121 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'GT' (2 nucleotides at position 130 to 131 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 6 nucleotides (from position 21 in the user submitted sequence), (do not cause frameshift) tctctggtgcctccatgagcagtAGTGCAtactactgGgggctgggtccgccagACcccccgggaagggggccggagtggattgggagtgtctactatggtggGgagcacctactacaaACcccgtcccGTccaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12413 JY8QFUQ01C4L01 productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12414 JY8QFUQ01CRYCJ No results 12415 JY8QFUQ01AXD9U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12416 JY8QFUQ01A4XSE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 958 93.98 203/216 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame - Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12417 JY8QFUQ01CXRN0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggatccaccttcaacaactatgccatgagttgggtccgccaggttccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 12418 JY8QFUQ01BQ5J2 No results 12419 JY8QFUQ01A6J0H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 402 88.24 90/102 nt 87.25 89/102 nt 8 8 X 8.8.X [1.16.X.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacat 12420 JY8QFUQ01AEZB2 productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgntccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 12421 JY8QFUQ01DSDR2 productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12422 JY8QFUQ01BISS5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 733 82.41 178/216 nt 81.48 176/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 82 to 84 in the user submitted sequence), (do not cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) ctcagggttcgttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 12423 JY8QFUQ01B6GAR productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12424 JY8QFUQ01DDI19 productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaggatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 12425 JY8QFUQ01C28YZ No results 12426 JY8QFUQ01C18G3 unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 12427 JY8QFUQ01CU9IP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagacccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12428 JY8QFUQ01C0ZKC unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1019 95.93 212/221 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CAWGGSG*#YFDYW out-of-frame - stop codons tctctggtggctccatcagcagtactagttactactggggctggatccgccagcccccagggaaggggctggagtggattggtaacattcattctagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcatggggtggttcgggttgaactactttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12429 JY8QFUQ01B3OI5 No results 12430 JY8QFUQ01AK799 No results 12431 JY8QFUQ01AMPES unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12432 JY8QFUQ01C1MJ4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactca 12433 JY8QFUQ01BTIW5 unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12434 JY8QFUQ01CPW3I productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggaccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12435 JY8QFUQ01DQTXL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12436 JY8QFUQ01B8BCF unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 915 90.91 200/220 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12437 JY8QFUQ01BEJ40 unproductive (see comment) Homsap IGHV3-48*04 F 1049 98.17 214/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-3*02 F 1 8 8 15 8.8.15 [1.17.38.11] CARGVVLAL*YLCGDYW in-frame + stop codons cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagaggggtcgtattggcattatgatacctttgcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12438 JY8QFUQ01BOL94 No results 12439 JY8QFUQ01AJ4MI productive Homsap IGHV3-13*01 F 864 90.87 189/208 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-19*01 F 3 7 7 16 7.7.16 [X.17.38.11] CVRRAVGHWQSNWYFDLW in-frame - attcaccttcagtaactacgacatgcactgggtccgccaatctacaggagaaggtctggagtgggtcgcatctattggtgttgctggtaatacaaactttccagactccgtggagggccgattcaccgtctccagggacaatgacaagaactccgtgtatcttcaaatgaacagcctgagacccggggacacggctgtgtattactgtgttagaagggcggtcgggcattggcagagcaattggtatttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12440 JY8QFUQ01ARV43 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12441 JY8QFUQ01AW7FQ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 912 92.06 197/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'TA' (2 nucleotides at position 82 to 83 in the user submitted sequence), (cause frameshift); ctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactatTAttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccaacccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12442 JY8QFUQ01CVT32 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactc 12443 JY8QFUQ01BZFPU unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 12444 JY8QFUQ01AYLQ4 No results 12445 JY8QFUQ01BDK1E No results 12446 JY8QFUQ01AUYHV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 402 88.24 90/102 nt 87.25 89/102 nt 8 8 X 8.8.X [1.16.X.X] null - No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacat 12447 JY8QFUQ01CVEEK productive (see comment) Homsap IGHV3-72*01 F 1093 98.67 222/225 nt 98.22 221/225 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [2.17.38.11] CLRPPRYDPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaAaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12448 JY8QFUQ01C1OMJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12449 JY8QFUQ01C1R2Y productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggGggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12450 JY8QFUQ01AGDVR productive Homsap IGHV3-30*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + cctctggattcaccttcaatattttttctatgcactgggtccgccaggctccaggcaagggactagagtgggtgtcacttgtttcatatgatggatctaagaaaaagtacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgctgcctggtcagggcttcttccc 12451 JY8QFUQ01DULJJ productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtgcttccccctggcaccctccctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12452 JY8QFUQ01DD9W8 unknown (see comment) Homsap IGHV3-74*03 F 137 52.72 97/184 nt 7 8 X 7.8.X [X.17.29.X] null + No rearrangement found stop codons attcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 12453 JY8QFUQ01BYOYM productive Homsap IGHV3-33*02 F 877 89.81 194/216 nt Homsap IGHJ1*01 F 197 86.54 45/52 nt Homsap IGHD6-6*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDRQDARAEHLQYW in-frame - tctggattcatcttcagtaattatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggctgttctgtggttcaatggaaatacgaagtattatgcagactccgtgaagggccgcttcaccatctccagagacacatccacgaacacgctgtttttgcaaatggacagcctgagagccgaggacacggctgtctattattgtgcaagagatcgtcaggacgcccgcgctgaacatctccaatactggggccagggcaccatggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12454 JY8QFUQ01ACHBJ unproductive Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [1.17.38.11] CARESWWSGFI#WYDPW out-of-frame - cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggctttataggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12455 JY8QFUQ01CAUD4 No results 12456 JY8QFUQ01AM7OF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12457 JY8QFUQ01CXH1Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARGVGQQLPPLDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); tctctcgtgcctccatGcaatatttcctactggagctggatccggcagcccccagggaggggactggagtggattggatatatctatgatagtgggagtaccaactacaAacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12458 JY8QFUQ01AZVJY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt 93.06 201/216 nt 8 8 X 8.8.X [1.17.37.X] null - No rearrangement found in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccaggggaaacctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12459 JY8QFUQ01DI5PB productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 12460 JY8QFUQ01BQAMA No results 12461 JY8QFUQ01CUUWD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12462 JY8QFUQ01B3VPS productive (see comment) Homsap IGHV4-39*07 F 862 87.84 195/222 nt 87.39 194/222 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-3*01 F 3 10 7 18 10.7.18 [2.17.38.11] CARGWAQQAGPTFVGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctgctggtggctccgtcagaagtaccagttactactGggggctggatccgccagcccccagggaaggggctggagtggattagtaacattcattctagtggaaccacctactacaacccgtccctcaagagtcgagtcaccatttcaatagacacgtccaacagccagttctccctgagcctgaggtctgtgaccgccgcggacacggctatctattactgtgcacgaggttgggcccaacaggcgggacctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12463 JY8QFUQ01CYY27 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARDNYGDY## out-of-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12464 JY8QFUQ01BMSOW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttaccaactatggcatgagctgggtccgccaggctcCcagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12465 JY8QFUQ01BPNQA productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 78 of V-REGION: 'AG' (2 nucleotides at position 135 to 136 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcgaAGtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12466 JY8QFUQ01C3JTT productive (see comment) Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.16.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 12467 JY8QFUQ01B8KUQ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 980 95.35 205/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [0.17.38.11] CARDSRHSASGSYSDYW in-frame - ctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12468 JY8QFUQ01DQVLD productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame - Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagataggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12469 JY8QFUQ01BRNQE productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccc 12470 JY8QFUQ01A0FII productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12471 JY8QFUQ01DHJ30 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1065 97.76 218/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 15 8.10.15 [1.17.38.11] CTTFGLTTVTKGYFDFW in-frame + ctctggattcactttcaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaacagagtacgctgcacccgtgaaaggcagatttaccatctcaagagatgattcaaaaaacacgctttatctgcaaatgaacagcctgaaaatcgaggacacagccgtgtattactgtaccacattcggcctgactacggtgactaaaggctactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12472 JY8QFUQ01AXKJ1 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12473 JY8QFUQ01AQ0N2 No results 12474 JY8QFUQ01A7K2I unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 804 85.98 184/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12475 JY8QFUQ01B9V2V No results 12476 JY8QFUQ01BB5MK unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12477 JY8QFUQ01BG4JY productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggagccagggaatcctggtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 12478 JY8QFUQ01DCSPK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12479 JY8QFUQ01BMWQ1 productive Homsap IGHV3-30*13 F 856 88.13 193/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [2.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggttccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12480 JY8QFUQ01BFX1E productive Homsap IGHV3-9*01 F 906 90.45 199/220 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [2.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - agcctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12481 JY8QFUQ01B4Q3C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12482 JY8QFUQ01C18QX No results 12483 JY8QFUQ01AGD1R unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 12484 JY8QFUQ01CGEIG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12485 JY8QFUQ01AO2LB No results 12486 JY8QFUQ01CSM0I productive (see comment) Homsap IGHV3-30*07 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [2.17.38.11] CASLGSYESSGPRW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcctcttcagtagttatgctatacactgggtccgccaggctccaggcaaggGggcttgagtgggtggcggttgtttcatatgatggaaataataaattttacgcagactctgtgaagggtcgatttagcctctccagagacaactccaagagcacggttgatctgcaaatggacaacttgagatccgaagacacggctgtatattattgtgcgagcctcggttcctatgagagcagtggtccccgatggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12487 JY8QFUQ01CJJYL productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gcctctggggttcaccgtcagtagcaaGgttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12488 JY8QFUQ01BUIDF productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctca 12489 JY8QFUQ01DJIQP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 917 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); tctggaattcagcttcagtacctaGtaacatgaactgggtccgccaggntccagggaaggggctggantgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12490 JY8QFUQ01CF7VI unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 947 94.34 200/212 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD2-21*02 F 3 7 8 X 7.8.X [X.17.38.11] CARDGGHSYGPSFDH## out-of-frame + gatacaccttcaccaggtacattatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagaggtgttagcagaagctacgcacagaagttccagggcagagtcaccatgaccaccgacacgtccacgagcacagtctatatggagctaaacagcctgagatctgaggacacggccgtttattactgtgcgagagatggagggcacagctatggaccctcctttgaccactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12491 JY8QFUQ01AY7BL No results 12492 JY8QFUQ01CKVX4 No results 12493 JY8QFUQ01BHGU1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKNVSLWFGDLL#YHFDYW out-of-frame + ctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaatgtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12494 JY8QFUQ01BR56L unknown (see comment) Homsap IGHV3-7*01 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ1*01 F (see comment) 23 70.0 7/10 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaGgggggtactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaccataaatcacgatggaagtcaaatttactatatggaccttgtgaagggccggttcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcttcttcc 12495 JY8QFUQ01A0OTP productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12496 JY8QFUQ01AGW5X No results 12497 JY8QFUQ01APG9M unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found tctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12498 JY8QFUQ01A7NVO productive (see comment) Homsap IGHV1-3*01 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGEPLGGDYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'G' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift); tggatacaccttcacttcttatgctgtaaactgggtgcgccaggcccccggacaAaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagtttcagggcagagtcaccattaccaGgggacacatccgcggacacagtcttcatggagctgagcagtctaagatctgaagacacggctgtgtattattgtgcgagagatggggagccactgggaggcgactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12499 JY8QFUQ01BWKNJ productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*02 F 3 10 7 17 10.7.17 [1.17.38.11] CARGVISLSGGNGDWFDPW in-frame + tctctggtgcctccatcagtagtggtaactactattggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatttataccagtgggagcaccaagtacaacccctccctcaaggatcgagtcaccatatcaacagacctgtcccagaaccacttctccctgaagttgaagtcaatgaccgccgcagactcggccgtgtattactgtgcgcgaggagtgatctctttatctggcggtaacggtgactggttcgacccctggggccagggaacccgggtcatcgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttc 12500 JY8QFUQ01CAH26 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12501 JY8QFUQ01AK776 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 995 93.39 212/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - tctccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12502 JY8QFUQ01CNW7H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtactaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12503 JY8QFUQ01CVOQV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.49 179/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] WCESPPTQWFSHPSTL#FDIW out-of-frame + Low V-REGION identity (82,49% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttagctcttttaccatgagctgggtccgccagactccggggaagggcctggaatgggtctctgctatcagtggcagcgatgatcgcacatcttatgttgactccgtgaagggccgcttcaccatctccagagacacttccaggaatacactgtttctgcagatgaacagcctgagcgccgaagatacggccacatacttttggtgtgagagtcccccaactcagtggttttcccacccttccacactcactttgacatctggggccagggaaccgtggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12504 JY8QFUQ01BP1SF No results 12505 JY8QFUQ01C57SN productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 815 86.24 188/218 nt 85.32 186/218 nt Homsap IGHJ6*02 F 187 79.66 47/59 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARRDSDFRMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 174 to 174 in the user submitted sequence), (cause frameshift); tgtctggatatgactttagcagattttggatcgcctgggtgcgccagatgcccgggaAaaggcctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctAttttttgagcagtctgagggcctcggacaccgccatgtatttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggaccacggtcaccgtgtctccaacatcccccggaccagcccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12506 JY8QFUQ01DOJQ3 No results 12507 JY8QFUQ01DA2RM unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 858 89.25 191/214 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [0.17.38.11] CARLGQLALDY## out-of-frame + gggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactgggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12508 JY8QFUQ01CYTAI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 705 81.31 174/214 nt 79.91 171/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatgggcCtgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgGcagactccgtgaGgggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggagctcag 12509 JY8QFUQ01DMWE4 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaTggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12510 JY8QFUQ01C9RMH productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12511 JY8QFUQ01BSW14 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 901 90.41 198/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) gtgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagccCcgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12512 JY8QFUQ01BN1FJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12513 JY8QFUQ01AU8X4 productive (see comment) Homsap IGHV4-61*04 F 945 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD2-15*01 F 3 10 7 18 10.7.18 [2.16.38.11] CARERRVAATASRAFGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) gtctctggtggctccgtcagcagtgctagtcactactggagctggatccgccagccccagggagggactggagtggattggatatatccttaacagtgggagcaccaacaacaacccctccctcaagagtcgagtcaccatatcagtggacgcgtccaagaaccaattcttcctgaagctgagctctgtgaccgctgctgacacggccttatattactgtgcgagagagagacgggtggcagccactgctagtcgggccttcggtatggacgtctggggccaagggaccacggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12514 JY8QFUQ01AZN8E No results 12515 JY8QFUQ01CJXFO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtcgacggtgtcgtggcaactcag 12516 JY8QFUQ01BNS72 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 890 90.7 195/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [1.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01BNS72 ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12517 JY8QFUQ01C3JXN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12518 JY8QFUQ01AJ597 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12519 JY8QFUQ01B8AC6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - gtctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 12520 JY8QFUQ01APK2R unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); cctctggattGcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagccttcaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12521 JY8QFUQ01BNGQY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12522 JY8QFUQ01CN4QR No results 12523 JY8QFUQ01CCPYX productive Homsap IGHV1-69*02 F 813 86.92 186/214 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [0.17.38.11] CATDHPRGRQSVYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tggggccaccttcaacagttatactttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcatctccacccttggtgtgacaaactacgcgcagaggttccagggcagagtcacgatctccgcggacaagtccacgacgacagcctacatggagttgacaaggctgacatttgaagacacggccgtttattattgtgcgacagatcatccccgcgggcgtcagtccgtgtactggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 12524 JY8QFUQ01CXOY1 No results 12525 JY8QFUQ01CTNGN No results 12526 JY8QFUQ01B9VAA productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 826 87.79 187/213 nt 85.92 183/213 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD3-16*01 F 3 8 7 15 8.7.15 [1.17.37.11] CARDGDFWELPGVLPIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 104 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 134 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 82 of V-REGION: 1 nucleotides (from position 148 in the user submitted sequence), (cause frameshift) gctctggattcacctttaatagctttgccatgagctgggtccgccaggctccagggaaggggccggagtgggtcgcattcattagtcgtaacagtcacataagctacgcggactcagtgaggggccgattcacatcgccatggacaatccaagaactcactgcttctgcaaatgaacagcctgagagccgaagacacggctgtctattactTgtgcgagagatggtgatttttgggagctaccaggagttcttccaatatggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12527 JY8QFUQ01CYJKV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDPW in-frame + ctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 12528 JY8QFUQ01CFMT5 productive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 12529 JY8QFUQ01CTPPL unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 832 87.5 189/216 nt 87.04 188/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaCgggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgagacgtcag 12530 JY8QFUQ01AC7WH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12531 JY8QFUQ01AH4E3 productive (see comment) Homsap IGHV3-7*01 F 923 92.45 196/212 nt 91.04 193/212 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [0.16.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctggattcacatttagtaactactggatgagctggtccgccaggntccaggaaggggctggantggtggccaacntaaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12532 JY8QFUQ01DHLIE productive (see comment) Homsap IGHV4-4*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt 8 7 9 8.7.9 [1.17.38.11] CARGDWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CA' (2 nucleotides at position 15 to 16 in the user submitted sequence), (cause frameshift); tctctggtggctccCAtccattaatcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtagtcataccagtggaagcaccaggtacaacccctccctcaagagtcgagtcaccgtgtcagcagacacgtccaagaaccagttctccctgaagcttagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggagactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12533 JY8QFUQ01B0G04 unknown (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 89.09 196/220 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatTttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12534 JY8QFUQ01CTZ8E productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12535 JY8QFUQ01AMPJP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaattttaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12536 JY8QFUQ01C67XX productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 940 93.06 201/216 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + tctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12537 JY8QFUQ01BWVGJ No results 12538 JY8QFUQ01A33F5 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctgagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12539 JY8QFUQ01CSWQD productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPRSVSRYSLFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatttttgtgcgagagatcctcgttccgtgagcaggtactctttatttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12540 JY8QFUQ01CIBDC productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12541 JY8QFUQ01DDBFR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 12542 JY8QFUQ01CLSH1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagcaaccataacatgaactgggtccGgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12543 JY8QFUQ01DLL36 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 916 90.54 201/222 nt 90.09 200/222 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD5-18*01 F 3 8 10 X 8.10.X [1.16.38.11] CTTAPSETYATEYFAMDV# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtaatgtttggatgaattgggtccgtcaggctccagggaagggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12544 JY8QFUQ01DM31P unproductive Homsap IGHV3-48*02 F 971 94.88 204/215 nt 93.95 202/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [0.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaTggggctggagtggatttcatacattagtggtagtggcggtGaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12545 JY8QFUQ01BSZ1W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctggtccagggcttcttcccccaggag 12546 JY8QFUQ01A3WPZ productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 12547 JY8QFUQ01DPW3O No results 12548 JY8QFUQ01CULSO productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 12549 JY8QFUQ01CUXO1 productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12550 JY8QFUQ01DK3GO productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 831 87.85 188/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 17 8.8.17 [0.17.38.11] CASDREDTAMITAESFNIW in-frame - tggaggcaccttcagtagacatgctatcaactgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcaccccactccttcatacaaccaaatatgcacagaggttccagggcagagtcacatttaccgcggacgaatccacggccacagtctacatgcaactgagcagcctgggatctgaagacacggccgtctattattgtgcgagcgatcgggaagatacagctatgattaccgcggagagttttaatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12551 JY8QFUQ01A3EIJ No results 12552 JY8QFUQ01C58KO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 12553 JY8QFUQ01CH5WU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 335 88.37 76/86 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 X X 10 X.X.10 [X.X.28.11] CARLGQLALDYW in-frame - tcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12554 JY8QFUQ01DP7SJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDPQQLLAEVNWFDPW in-frame + ctctggattcacctttcgcagctatgccatgagttgggtccgccaggctccaggaaggggactagagtgggtctcgtctataagtggtagtggtgataaaacaaagtatgcagactccgtgaagggccggttcaccatctcccgagacaatgccaggaacactttttatctgcaaatgaacagcctcagagccggggacacggccgtctattactgtgcgaaagatcctcagcagttattggcagaagtaaactggttcgacccttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12555 JY8QFUQ01BNY5Q No results 12556 JY8QFUQ01C18IM productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F 886 90.28 195/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [2.17.38.11] CVREVTGVWDWFDPW in-frame - gcctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactctgtgaagggccagttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12557 JY8QFUQ01B7DGU productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12558 JY8QFUQ01B199R productive Homsap IGHV3-49*04 F 1048 96.44 217/225 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [2.17.38.11] CTKCSVTIYFFDYW in-frame - gcctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12559 JY8QFUQ01CDN1K unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 860 88.53 193/218 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CTRVGTFNWF#PW out-of-frame - cctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12560 JY8QFUQ01BZPI8 No results 12561 JY8QFUQ01AXNMX No results 12562 JY8QFUQ01AOFRF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [2.17.38.11] CATSRGSANWYPFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12563 JY8QFUQ01BDHEG productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12564 JY8QFUQ01B5ZUI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12565 JY8QFUQ01B7DZ7 productive Homsap IGHV3-33*03 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame - cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12566 JY8QFUQ01AT5TS productive Homsap IGHV1-24*01 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagtatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12567 JY8QFUQ01BNLPI productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 7 8 14 7.8.14 [1.16.38.11] CARVIPGRGNYAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) cctctggattcgactttggtattattggatgagttgggtccgccaggctccagggaagggactggagtggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12568 JY8QFUQ01C4SDR productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 500 80.65 125/155 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 X 7 9 X.7.9 [X.6.38.11] CARLDGHFDLW in-frame + Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcgcctcatcatctccagagacgaatccaagagtgagctgtatcttcggatgacgaaagtgaaagccgaagacgcggccgtatattactgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12569 JY8QFUQ01AOQJV productive (see comment) Homsap IGHV3-7*01 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 7 8 15 7.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) tctacattcacgtttagtcggtatggatgagctggtaccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12570 JY8QFUQ01B1N1T productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDPGNYWGYYYDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gtctggattcacctttagtgattatgcCcttgagctgggtccgccagactcccgggaAaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12571 JY8QFUQ01AY44B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12572 JY8QFUQ01BDSWE No results 12573 JY8QFUQ01AGTKI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12574 JY8QFUQ01BCLBD unproductive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [0.17.38.11] CARVIPGRGNYAF*CL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift); ctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacgGgctgtgtattactgtgcgagagttattcccggccggggaaactatgctttttgatgtctgggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggttcagggcttcttccccca 12575 JY8QFUQ01CZA6T unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12576 JY8QFUQ01B26V1 No results 12577 JY8QFUQ01CUYP4 productive (see comment) Homsap IGHV1-3*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGRYDISGRGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tggatacaccttcactagttTttagtatacattgggtgcgccaggcccccggacagaggcttgagtggatgggatggatcaacgcaggcaacggtcacacaaaatattcacagaagttccaggacagagtcaccattataagggacacatccgcgagcacagcctacatggacctgagcaccctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatattagtggtcgtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaagggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 12578 JY8QFUQ01DD5SJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*01 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVRDRDFLWGSYRLQLEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); gctctggattcagatttagcagctatggcatgagctgggtccgccaggctccCAaaaaaaggggctggagtgggtctcaggaattagtgcgaatggtggtagtataaattatgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacattgtttctgcaaatgaatagcctgagagccgaagacacggccgtatattactgtgtgagagatcgcgatttcctgtgggggagttatcgtcttcaacttgaatattggggccaaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12579 JY8QFUQ01ACN1F unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 993 96.26 206/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARADNYDSLGLKFDP# out-of-frame + ctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 12580 JY8QFUQ01B3PPT No results 12581 JY8QFUQ01CM85M productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 12582 JY8QFUQ01C68HQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattgGgtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggacgtggtcatcgcctgcctggtccagggcttcttccccca 12583 JY8QFUQ01DEDQS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 711 81.11 176/217 nt 80.18 174/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [2.17.38.11] CARHLMVYALDVW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DEDQS ; 8 AA in Homsap_IGHV3-23*01), and low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggcaaGggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaAaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12584 JY8QFUQ01DMSS9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12585 JY8QFUQ01BIHKO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 12586 JY8QFUQ01AZMAF productive (see comment) Homsap IGHV4-39*03 F 928 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 7 17 9.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12587 JY8QFUQ01AINHD productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12588 JY8QFUQ01BARB3 productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARDSVPRASEAAYYFDSW in-frame - tggatacagcttcactaatcacattatccattgggtgcgccaggccccaggcaaggggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacgagtgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12589 JY8QFUQ01AMUT4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagAccctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12590 JY8QFUQ01DDUL2 productive Homsap IGHV3-64*02 F (see comment) 784 84.47 185/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVRGRPMAGFHGILYDNW in-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttagtatcagtaattatggtattcactgggtccgccaggctccagggaggggactggaacttgtttcagctattaccaacaatgcgcatagtgtagtctatgtagactctgtgaagggcagattcatcatctccagagactattccaagaacacgttgtatcttcaaatgggcagactgagaccagaagacacggctgtgtactactgtgtcagagggcggcctatggctggctttcatggaatcctttatgacaactggggcctgggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12591 JY8QFUQ01ABDGN No results 12592 JY8QFUQ01DI2QI unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + cgtctggattcaacttcaatagttttggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12593 JY8QFUQ01BG4R5 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 136 55.47 76/137 nt 10 9 X 10.9.X [1.17.8.X] null + No rearrangement found stop codons ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12594 JY8QFUQ01CK2EG productive (see comment) Homsap IGHV3-7*01 F 959 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacntaaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12595 JY8QFUQ01DGJUU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcgccctgctctaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12596 JY8QFUQ01ALOE8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 167 94.59 35/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcaccttcagtcgttatagcatgaactgg 12597 JY8QFUQ01BIPTQ No results 12598 JY8QFUQ01A5322 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [2.17.38.11] CARVMREHYYGAGNYPWGGMEVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcacAttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12599 JY8QFUQ01BAJOS unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12600 JY8QFUQ01A5EZ5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12601 JY8QFUQ01BUH5X No results 12602 JY8QFUQ01AN3YW No results 12603 JY8QFUQ01C045Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKEGPTLLTRPPLNW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgcccccctctcaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12604 JY8QFUQ01A48ML No results 12605 JY8QFUQ01DBWQD productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12606 JY8QFUQ01ABWLU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12607 JY8QFUQ01CZIAW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgaccttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 12608 JY8QFUQ01BTTE3 No results 12609 JY8QFUQ01DQWJW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.05 185/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - tntctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12610 JY8QFUQ01AFROA unproductive Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGRRGNYYWGI#DSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacGaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12611 JY8QFUQ01BZYY1 unproductive (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKEEF*HWLDTTG##W out-of-frame + stop codons ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaattttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12612 JY8QFUQ01AVUCF unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 157 57.46 77/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tctggattcatcttcagtgactactacatgacctggatccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12613 JY8QFUQ01CH338 productive (see comment) Homsap IGHV3-64*02 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 7 8 10 7.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcatttcagtacttatcctatgcactgggtccgccaggctccagggaaggGgactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12614 JY8QFUQ01CNAQL No results 12615 JY8QFUQ01B0630 No results 12616 JY8QFUQ01DVS1K productive (see comment) Homsap IGHV1-18*01 F 1002 96.73 207/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARNIVGAPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GGG' (3 nucleotides at position 44 to 46 in the user submitted sequence), (do not cause frameshift); tggttacacctttaccagctatggtatcagctgggtgcgacaaGGGccccctggacacgggcttgagtggatgggatggatcagcgcttacaatggtaacacaaagtatgcacagaagctccaggacagagtcaccatgaccacagacacatccacgagcacagcctatatggagctgaggagcctgagatctgacgacacggccgtttattactgtgcgaggaatatagtgggagctccttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12617 JY8QFUQ01BHY7V unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12618 JY8QFUQ01B1EO9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12619 JY8QFUQ01CXO19 No results 12620 JY8QFUQ01BFFC2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 12621 JY8QFUQ01CSKA2 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12622 JY8QFUQ01ATM5X productive (see comment) Homsap IGHV3-11*01 F 795 85.98 184/214 nt 84.58 181/214 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD5-12*01 F 2 8 8 14 8.8.14 [1.16.38.11] CARDRRPWSFDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) tctggattcaccttcagGggactactatatgagttggattcgcctggcactgggaaggggctgagtgggtttcatatattagtggtaatgtgtttaccaaacactacgcagactctgtgcagggccgattcaccatctccagggacaacgacaataagacagtctatctacagatggacaacctgagagccgcagacacggccatgtattactgtgcgagagacaggcgcccatggtcttttgatgcttttgatgtctggggccgggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12623 JY8QFUQ01A95OK No results 12624 JY8QFUQ01B3M1E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 387 76.3 103/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found Low V-REGION identity (76,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12625 JY8QFUQ01CVGS4 No results 12626 JY8QFUQ01BKNOD productive (see comment) Homsap IGHV1-3*01 F 816 87.68 185/211 nt 86.26 182/211 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.16.37.11] CVRGRSPPGDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tggatacaccttcactaattatgctctgcaatgggtgcgccgggccccggacaaactttgagtggctgggatggatcaactctgccaatggcaacacaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12627 JY8QFUQ01BLJYE productive (see comment) Homsap IGHV3-11*01 F (see comment) 765 83.87 182/217 nt 83.41 181/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcagcttaagtgactactacatgacctgggtccgccaggccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaccgtctccagggacaacgtccaaaactcactgTtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12628 JY8QFUQ01DCXPQ unproductive Homsap IGHV3-74*03 F 1031 97.25 212/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CATGPDYAYAM## out-of-frame + cctctggattcaccttcagtcgctactggatgcactgggtccgccaagctccagggaagggcctggtgtgggtctcacgtattaaaagtgatgggattagcacaacgtacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtactactgtgcaaccgggcccgattatgcgtatgctatgtgggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12629 JY8QFUQ01CFBAE No results 12630 JY8QFUQ01A5EG9 unproductive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CAREPQSNAL#YYFDHW out-of-frame + stop codons tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgccctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12631 JY8QFUQ01BPDKM productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12632 JY8QFUQ01BED3K No results 12633 JY8QFUQ01CHRAU unknown (see comment) Homsap IGHV3-7*02 F 99 58.02 47/81 nt 8 1 X 8.1.X [0.17.X.X] null - No rearrangement found ctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12634 JY8QFUQ01CM18U productive Homsap IGHV1-3*01 F 871 90.14 192/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [X.17.38.11] CARDGYRSGNGADYW in-frame + ggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12635 JY8QFUQ01C884V No results 12636 JY8QFUQ01DDY3L productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 823 87.04 188/216 nt 86.11 186/216 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctgggattcagcttaagttcttatGggcatgaactgggtccgccaggctccaggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12637 JY8QFUQ01ARPRY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 12638 JY8QFUQ01AYMEF No results 12639 JY8QFUQ01BL1H2 productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 92.66 202/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.16.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'AT' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) gcctctggaATttaacctttagaaccttttggagagctgggtccgccaggctccagggagggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12640 JY8QFUQ01DM9RK No results 12641 JY8QFUQ01C0B16 productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 82.81 183/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccCatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc 12642 JY8QFUQ01BQ8FU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CAGHLLGDPFDYW in-frame + ctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 12643 JY8QFUQ01CWZQ1 productive (see comment) Homsap IGHV3-7*01 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-21*02 F 2 7 8 18 7.8.18 [1.17.38.11] CSRHGGYTRLYNQNVYLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) tctggattcacatttagcaactttggatgagctgggtccgccagactccagggCaaggggctggagtgggtggccaaaataaacccagacggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgagactctacaatcaaaatgtctaccttgactactggggccagggagcctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 12644 JY8QFUQ01B8FO0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 721 81.28 178/219 nt 80.82 177/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [2.17.38.11] CAKDQYGSPSDFDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 85 to 87 in the user submitted sequence), (do not cause frameshift); acctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12645 JY8QFUQ01A9ABS unproductive (see comment) Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARAPF*LL# out-of-frame + stop codons ctctggattcatctttagtagctatagtatgaactgggtccgccaggctccagggaaggggccggagtgggtttcatacattagcggtagtagtagctccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagcccccttttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 12646 JY8QFUQ01B2IQ1 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12647 JY8QFUQ01DL5VS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 12648 JY8QFUQ01C09W0 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaCcctttggttattatggcatggactgggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12649 JY8QFUQ01A01KX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtntcgtgggaactcag 12650 JY8QFUQ01DJA9X productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12651 JY8QFUQ01CEQK9 unproductive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CSRDGRRAT#LDSW out-of-frame + cctctggattcacctttagcagacattggatgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtcagagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggagggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 12652 JY8QFUQ01DLMYL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 848 89.15 189/212 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [X.17.38.11] CARLGQLALDYW in-frame - cggatcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12653 JY8QFUQ01CR261 No results 12654 JY8QFUQ01BNBTY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame + gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12655 JY8QFUQ01AFTSH productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame + tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12656 JY8QFUQ01CHEHR productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12657 JY8QFUQ01A9JAF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 841 87.96 190/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + tctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12658 JY8QFUQ01AJ7NL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12659 JY8QFUQ01CM2BA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 725 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); cctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12660 JY8QFUQ01CVG4H unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ4*03 F 123 72.92 35/48 nt Homsap IGHD6-13*01 F 3 8 7 X 8.7.X [1.17.38.11] CARPTYSSGRDAF*YL# out-of-frame + stop codons in FR3-IMGT at codon 82 of V-REGION: 'C' (1 nucleotides at position 147 to 147 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacCacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgctttttgatacctgggggccaagggacgacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12661 JY8QFUQ01BP7Y0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGataatttcctactggggctggatccgccagcccccagggaagggactgcagtggaCttgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcttggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12662 JY8QFUQ01BLV23 productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 12663 JY8QFUQ01CEEZ2 productive Homsap IGHV4-39*03 F 924 91.32 200/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12664 JY8QFUQ01BW75G No results 12665 JY8QFUQ01B7XRE unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 435 76.67 115/150 nt 8 7 X 8.7.X [1.17.16.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B7XRE ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,67% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag 12666 JY8QFUQ01AK7YT productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*06 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 8 22 8.8.22 [1.17.38.11] CARDFLAPNRFGVFDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggtctggaatggttggcaatgatatggtatgatggaaataAaaaaatactacgcagactccgcgacgggccgattcaccatctccagagacaattctgagtacacgctgtctcttcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagggatttcttagccccgaatcgttttggagtgtttgactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12667 JY8QFUQ01A3KGM productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-22*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARDGGHHEDDGYYNFYYALDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cgtctggattcagcttcaatagatatggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcagtaatttggtatgatggaaaaaacaaatattatgcagactccgtgaagGggccgattcgccatctccaaagacaattccaagaatacggtggatttggagctgaacagtttgagagtcgaagacacggctgtttattactgtgcgagagatggaggccaccatgaagacgatggttattacaacttctactatgctttggacgtttggggccaagggaccacggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12668 JY8QFUQ01A481A unknown (see comment) Homsap IGHV3-38-3*01 ORF 100 53.12 68/128 nt 8 7 X 8.7.X [0.17.11.X] null - No rearrangement found stop codons tggattctccgtcagtttcaactacatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12669 JY8QFUQ01ALMXP productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12670 JY8QFUQ01AHKU0 productive Homsap IGHV3-48*02 F 971 94.88 204/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [0.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame - ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12671 JY8QFUQ01DDG20 unproductive Homsap IGHV3-48*04 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDSSRWGYYYYGLDVW# out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcatcttcactagttacagtctgaactgggtccgccaggctccagggaaggGggctggagtgggttgcatacattagtagtagtagtagtaccatagactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatagtagcaggtggggctactactactatggtttggacgtctgggggtccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggtaacgtggtcatcgcctgcctggtccagggcttcttccc 12672 JY8QFUQ01CTI2D No results 12673 JY8QFUQ01A4ISC productive (see comment) Homsap IGHV1-18*01 F 938 93.87 199/212 nt 93.4 198/212 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [X.16.38.11] CARGDYFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) ggttacacctttaccagctatggtctcagctgggtgcgacaggccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12674 JY8QFUQ01CHSS6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + gttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12675 JY8QFUQ01BVJ75 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12676 JY8QFUQ01CSWDZ No results 12677 JY8QFUQ01DISX1 No results 12678 JY8QFUQ01CM1UV No results 12679 JY8QFUQ01DI7OP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12680 JY8QFUQ01CSA0F productive Homsap IGHV1-18*01 F 862 89.67 191/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [X.17.38.11] CARVPGYGSGPWFFDYW in-frame + ggttacacctttagcagcaatggtatcagttgggtgcgacaggcccctggacaagggcttgagtggctgggcaggatcaacgtatacaatggtaacacggaatatgcagaggacttccagggcagagtcaccatgaccacggacacatccacgaacacagcctatattgaagtgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagtccccggatatggttcgggcccgtggttttttgactactggggccagggaaccctggtcatcgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 12681 JY8QFUQ01A1I7O No results 12682 JY8QFUQ01CBQ13 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 7 8 10 7.8.10 [2.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 74 of V-REGION: 'GC' (2 nucleotides at position 128 to 129 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift) gcctctggattcatctttgatgatttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggGCccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12683 JY8QFUQ01DA01D productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12684 JY8QFUQ01CBXUV unproductive (see comment) Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARDELPWGYNR#YYFDYW out-of-frame + stop codons ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttggggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 12685 JY8QFUQ01CYOOE unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.16.38.11] CVSDLAGQKGF#W out-of-frame + in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggcggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggttttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12686 JY8QFUQ01AO80F No results 12687 JY8QFUQ01B7XX9 productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12688 JY8QFUQ01BLCKL productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12689 JY8QFUQ01ATKPT productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12690 JY8QFUQ01A7Z02 No results 12691 JY8QFUQ01BFCE0 unproductive (see comment) Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-1*01 F 3 10 7 X 10.7.X [1.17.38.11] CTRHPEV*CRG#DSW out-of-frame + stop codons tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccggaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagccctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12692 JY8QFUQ01A6QNU productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12693 JY8QFUQ01BV2YE productive (see comment) Homsap IGHV1-2*02 F 780 85.78 181/211 nt 84.83 179/211 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-16*02 F 2 8 7 15 8.7.15 [0.16.38.11] CARHYCDTNGVCDFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 2 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tggatacagcttcaccgactttcatattcattgggtgcgacaggaccctggacaagggcttgagtggatgggtggaccacctaaaaatggcggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggaaatgagcaggctgagatctgacgacacggccatttattactgtgcgagacattattgtgacaccaacggcgtctgtgattttgatatctggggccaggggacaaaggtcatcgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12694 JY8QFUQ01B206Z No results 12695 JY8QFUQ01C0IOK productive Homsap IGHV3-7*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + tctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacatggtcgtcgcatgcctggtccagggcttcttccccca 12696 JY8QFUQ01A2WCO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 760 83.8 181/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggatcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12697 JY8QFUQ01DJ2FZ No results 12698 JY8QFUQ01CHCZ3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 12699 JY8QFUQ01B2HX0 unproductive (see comment) Homsap IGHV1-58*02 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 193 84.91 45/53 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [0.17.38.11] CAAVLAGWGFY##FDFW out-of-frame + stop codons tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattgacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12700 JY8QFUQ01AQJ3U productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12701 JY8QFUQ01DD82F No results 12702 JY8QFUQ01AO6RW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 1 8 7 14 8.7.14 [2.17.38.11] CARCKSAGLVDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcagcattagcgactatgccatggcctgggtccgccaggctccagggaaggggccggagtgggtctcaagtgttactaatggttttggcacatactacgcagactctgtgaagggccggttcaccgcctccagagacaattccaagaacgcattgttcttggaaatgaacatcctcagagccgaggacacggccgtatattattgtgcgaggtgtaagtcggccggtttggtggactggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12703 JY8QFUQ01ALD6W productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12704 JY8QFUQ01CQ2DI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - cctctcgattcacctttagcagctatgtcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 12705 JY8QFUQ01CNGVF productive Homsap IGHV4-61*02 F (see comment) 609 75.45 166/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERDKSVGGANDFDSW in-frame + Low V-REGION identity (75,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccagtggccccatgatgagtcgtgacttctattggacttggatccggcagcccgccgggggggaactagaatggatcggacgtgtttacattggtgggatgaccaataacagtccctccttcaggggtcgactgagcatgtccatagacccgaccaggaggcagttctccatgaccttgacgtctgtgaccgccgcagacacggccatgtattactgtgcgcgagaacgtgataagtcggtcggcggagcgaacgactttgattcctggggccagggagtcctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12706 JY8QFUQ01AT8YT productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); tggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12707 JY8QFUQ01BAGI4 productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CVTDILRVGVTYYFDYW in-frame + ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtggtagtggtgacgacatacattatgcagactctgtgaagggccggttcaccatctccagggacaacgccaagaattcattgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgacagatatccttagagtgggagttacatattactttgactactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12708 JY8QFUQ01BYN47 productive Homsap IGHV1-18*01 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [0.17.38.11] CVREESIVVVTGRRGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccatgtattattgtgttagagaagagtcaattgtggtggtgaccgggcggcggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12709 JY8QFUQ01CB2DX productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1105 100.0 222/222 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD6-6*01 F 2 8 10 16 8.10.16 [1.17.38.11] CTRRSIADNFYYYGMDVW in-frame - tctgggttcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagcaaagctaacagttacgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtactagacggagtatagcagataacttctactactacggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12710 JY8QFUQ01AK1KM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12711 JY8QFUQ01AKUHI productive Homsap IGHV3-7*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDPYKPGSGNPGFDYW in-frame - ctctggattcacctttagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12712 JY8QFUQ01B0MR8 productive (see comment) Homsap IGHV3-72*01 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 9 11 8.9.11 [1.17.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12713 JY8QFUQ01BM9UG No results 12714 JY8QFUQ01AI884 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 387 84.26 91/108 nt 8 8 X 8.8.X [1.17.1.X] null - No rearrangement found Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagact 12715 JY8QFUQ01B70J3 productive Homsap IGHV1-24*01 F 970 95.31 203/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12716 JY8QFUQ01CDVE2 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 2 9 7 15 9.7.15 [1.17.38.11] CLRCHFGTGYYYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'GT' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); gatctggtggctccatcgccagtagtaactggtggagAttgggtccgccaGTgcccccagggaaggggctggagtggattggagagatctatcatactgggaccgtcaactacaacccgtccctcatcagtcgagccaccataggagtggacaagtccaagaatgagctctccttgaggctgacctctgtgaccgtcgcggacacggccgtatattattgtttaagatgtcactttgggactggttattattactactttgactactggggccagggattgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12717 JY8QFUQ01CWCJ9 No results 12718 JY8QFUQ01DMWYP productive (see comment) Homsap IGHV1-8*01 F 911 92.45 196/212 nt 91.98 195/212 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [X.16.38.11] CAREGLLGSLGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaaggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12719 JY8QFUQ01CFDIP No results 12720 JY8QFUQ01CGYVT unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 1 8 7 9 8.7.9 [4.17.38.11] CARGAPFS**C in-frame + stop codons cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12721 JY8QFUQ01BJ8F9 unproductive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1020 95.52 213/223 nt Homsap IGHJ5*01 F 84 62.75 32/51 nt Homsap IGHD4-11*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CARHEGTPVSDVGGYGMDV## out-of-frame + ctctggattcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggaatgggttggccgtattagaagcagagcttacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggccaaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatggcctggtccagggcttcttccc 12722 JY8QFUQ01CGNPK productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12723 JY8QFUQ01A1GVS unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12724 JY8QFUQ01AMZKQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12725 JY8QFUQ01COOKR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-17*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKNMGDYMGAPIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttaccacctacgccatgagctgggtccgccaggctccagggaaggggctggagtggctctcagatatcagtggtagaggttataacacatattacgcagcttccgtgaagggccggttcgccatctccagagacaattccgacaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaacatgggtgactacatgggcgccccaattgactcctggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12726 JY8QFUQ01BTCFS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12727 JY8QFUQ01DKQAQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12728 JY8QFUQ01CCXWM No results 12729 JY8QFUQ01BGT9K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 12730 JY8QFUQ01BW1U7 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12731 JY8QFUQ01B9S8H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggactggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12732 JY8QFUQ01CV7GP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12733 JY8QFUQ01AE42X No results 12734 JY8QFUQ01DNA2K No results 12735 JY8QFUQ01C94TN productive (see comment) Homsap IGHV3-48*01 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12736 JY8QFUQ01C99TV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12737 JY8QFUQ01C62BK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tttcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgatggtgtcgtggaactc 12738 JY8QFUQ01BL9OM productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 75 of V-REGION: 'GGCT' (4 nucleotides at position 127 to 130 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcgGGCTtgaatcgatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12739 JY8QFUQ01CMLF2 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - tggttacacctttactacctatggcatcagctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggaaatacaaactctgcacagaagttccaggacagagtcaccctgaccacagacacatccacgagcacagcctacatggagctgaggaacctgagatctgacgacacggccgtgtattactgtgcgagagtaattcggaccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12740 JY8QFUQ01CLCA0 productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12741 JY8QFUQ01CGUKQ productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12742 JY8QFUQ01BQ6NC productive (see comment) Homsap IGHV3-48*03 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctctgggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12743 JY8QFUQ01CPR1X productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [2.17.38.11] CARLGQLALDYW in-frame - tgttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12744 JY8QFUQ01A7II3 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 827 85.71 192/224 nt 84.82 190/224 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [2.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tctctggctggcatgccatcagcagtGataatttcctactggggctggatccgccagcccccagggaagggactgcagtggaCttgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12745 JY8QFUQ01AB534 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 818 86.98 187/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AB534 ; 8 AA in Homsap_IGHV3-21*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccggttcaccatatccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12746 JY8QFUQ01ACT90 productive (see comment) Homsap IGHV4-39*02 F 839 86.88 192/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctgGgggctggatccgccagcCccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12747 JY8QFUQ01AG2YX productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 7 8 13 7.8.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) gtctggattcatctcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12748 JY8QFUQ01AG5FJ productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12749 JY8QFUQ01CJYGN productive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 20 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcacatttagtGAattcattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12750 JY8QFUQ01ACRUV productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12751 JY8QFUQ01AO9EO unproductive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1017 96.77 210/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDLYDSSGS#FDYW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) cctctggattcaGccttcagcagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtaggagtagtaccaaaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagatttgtatgatagtagtggttccttttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttctccgaaccggtgacggtgtcgtggaactcag 12752 JY8QFUQ01AGL81 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 672 80.09 169/211 nt 79.62 168/211 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [0.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 76 of V-REGION: 'TTA' (3 nucleotides at position 125 to 127 in the user submitted sequence), (do not cause frameshift); tgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcTTAtcgacagtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12753 JY8QFUQ01CS6WP productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12754 JY8QFUQ01C3JRT productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12755 JY8QFUQ01CWUN1 productive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - gcctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12756 JY8QFUQ01AVHAA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*02 F 3 8 8 23 8.8.23 [1.17.38.11] CARDRRVFFGQLITTKIYHYGMDVW in-frame - ctctggattcaacttcaattattatagcatgagttgggtccgccaggctccgggaaagggactggagtgggtttcatacattagtactagtagtagttacatgtattacacggactccgtgaagggccgcttcaccgtctccagagacaacgccaagaaatctctgtatctggaaatgaacagcctaagggacgaggacacggctgtctacttttgtgcgagagatcgacgagtgttctttggacaattaataaccaccaaaatctaccactacggcatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12757 JY8QFUQ01DI2UC No results 12758 JY8QFUQ01BZF4D productive (see comment) Homsap IGHV4-4*07 F 1043 98.6 212/215 nt 97.67 210/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [2.16.38.11] CARDFSNRGWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagtagtttctacCtggagctggatccggcagcccggccggaagggactgagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12759 JY8QFUQ01DLNKW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGEFYYETSGRRGFDYW in-frame - ctctgggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12760 JY8QFUQ01BYWUJ No results 12761 JY8QFUQ01AE3VD productive Homsap IGHV3-11*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaaaaactcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatattggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12762 JY8QFUQ01AUYQV productive (see comment) Homsap IGHV3-66*02 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-16*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAALHDPPWGWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaagggtctggagtgggtctcagttaAtttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12763 JY8QFUQ01CJ1RG No results 12764 JY8QFUQ01AIY7F productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctggattcacctacagcagcGtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12765 JY8QFUQ01BQDLT productive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacgaccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12766 JY8QFUQ01APUQX unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12767 JY8QFUQ01A1HLF No results 12768 JY8QFUQ01CAVAP No results 12769 JY8QFUQ01B7HDA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12770 JY8QFUQ01CX9PA No results 12771 JY8QFUQ01AFSUH productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12772 JY8QFUQ01AC5OX productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 12773 JY8QFUQ01BEVTU productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); gtctctgtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12774 JY8QFUQ01DWST2 No results 12775 JY8QFUQ01ANMI2 No results 12776 JY8QFUQ01DLCNB productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcatgtttagtaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggtagtgagacttactatgtggaatctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12777 JY8QFUQ01BB7R1 No results 12778 JY8QFUQ01C0MRY productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12779 JY8QFUQ01BJQ7G unknown (see comment) Homsap IGHV4-4*07 F 890 90.7 195/215 nt 89.3 192/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'TGATTC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagTGATTCtcactactggagttggatccggcagcccgccggGgaagggactggagtggattgggcgtgtctacgccagtgGggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttcagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12780 JY8QFUQ01DPWBS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKGDSGGYTHNYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaAggggctggtgtgggcctcacgtgttaatggtgatAgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12781 JY8QFUQ01B641M productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKELGRALTGNYYQYFHYW in-frame + cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaattggggagggccctgactgggaactactaccagtactttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12782 JY8QFUQ01C15RE No results 12783 JY8QFUQ01AWG3V No results 12784 JY8QFUQ01DDBA4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12785 JY8QFUQ01BDETF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12786 JY8QFUQ01A0T6U productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 12787 JY8QFUQ01CQHK4 productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12788 JY8QFUQ01DWVH3 unknown (see comment) Homsap IGHV1-2*02 F 487 86.72 111/128 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg 12789 JY8QFUQ01CC0UX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12790 JY8QFUQ01CZQ5A No results 12791 JY8QFUQ01BTSHB No results 12792 JY8QFUQ01DPAOU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12793 JY8QFUQ01BBGM9 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12794 JY8QFUQ01CH1XL No results 12795 JY8QFUQ01AJ5JP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccag 12796 JY8QFUQ01CQDCU No results 12797 JY8QFUQ01CF50U No results 12798 JY8QFUQ01AURP9 productive Homsap IGHV3-30*10 F (see comment) 702 80.65 175/217 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 1 8 8 16 8.8.16 [1.17.38.11] CSRGTTGTTDDSRLFQHW in-frame + Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12799 JY8QFUQ01DBZZM productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + tctctggtgactccatcagcagtaatagtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12800 JY8QFUQ01BXI5C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccggctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 12801 JY8QFUQ01B8M0D unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 514 73.0 146/200 nt 72.5 145/200 nt 8 7 X 8.7.X [2.17.31.X] null - No rearrangement found Low V-REGION identity (73,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 85 in the user submitted sequence), (cause frameshift) agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtatagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtcatcgcctgcctggtccagggcttcttccccca 12802 JY8QFUQ01B7TWW productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12803 JY8QFUQ01CEETY productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 704 81.6 173/212 nt 81.13 172/212 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 129 in the user submitted sequence), (cause frameshift) tctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12804 JY8QFUQ01AFU1L unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 107 79.41 27/34 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found ctctggattcacctctcctagatactggatgaat 12805 JY8QFUQ01BNYA6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12806 JY8QFUQ01B28V3 productive Homsap IGHV3-11*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDDSCSGGSCYEYW in-frame - cctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12807 JY8QFUQ01CKN3U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSDYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); cctctggattcagGttttagttcttatgGgcatgaactgggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgaaagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 12808 JY8QFUQ01BKCAT unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12809 JY8QFUQ01AHPL4 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 12810 JY8QFUQ01A5N4V unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-30*05 F 147 53.23 99/186 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12811 JY8QFUQ01C76IX No results 12812 JY8QFUQ01B6LCX unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 750 83.18 178/214 nt 82.24 176/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.37.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift) tctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgagggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacggcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12813 JY8QFUQ01BZCBT No results 12814 JY8QFUQ01B1CH3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); ctctggattcaGcctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12815 JY8QFUQ01C3YLX No results 12816 JY8QFUQ01DTZ4U productive (see comment) Homsap IGHV4-59*03 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'AC' (2 nucleotides at position 161 to 162 in the user submitted sequence), (cause frameshift); ccgtctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagcccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaACccaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12817 JY8QFUQ01B6R1S unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 3 8 7 X 8.7.X [1.17.38.11] CARGDGLR#DYW out-of-frame + ctctggattcaccgtcaatagaaactacataagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacgggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12818 JY8QFUQ01DVIT1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 846 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-10*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARRNYFGSGSSYNVAGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ttttggatacacctttcccacctactggctcgcctggttccgcctggtgcccgggaaaggcccggagtgggtggggatcatctatcctggtgactccgataccacctatagcccgtccttccaaggccgagtcaccatctcagtcgacctgtccagccgcaccgcctatctgcagtggggcagcctgaaggcctcggacaccgccatctattactgcgcgagacgaaattactttggttcggggagttcttacaatgttgccggcttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12819 JY8QFUQ01CHXLI productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 971 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-3*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARGTRLRDFWSGYPLGGFGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctatggtggatccttcagtaattactactggagctggatccgccagTcccccaggggaggggctggagtggattggggaaatcaatcatagtggaagcacgaagtacaatccgtccctcaagaggcgagtcaccatttcagtagacacgtccaagaatcagttctccctgaagctgagttctgtgaccgccgcggacacggctgtgtattactgcgcgagaggcacccgtttaagggatttttggagtggttaccccctgggggggttcggtatggacgtctggggccaagggaccacggtcaccgcctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12820 JY8QFUQ01BPLPH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 7 8 15 7.8.15 [1.17.38.11] CAKDQVAGDGYVTYDDW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) cctctggattcactttagcagctatgccatgggctgggtccgccaggctccagggaaggGggctggagtgggtcgcaagtatgagcggtagcggcaagaccatagagcacgcagaccccgtgaagggccggttcaccatctccagagacaactccaagaacacagtgtatctgcaaatgaacagcctgagagccgaagacacggccgtctattactgtgcgaaagaccaggtcgccggagatggttacgtgacctatgacgactggggccagggaaccctggtcaccatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12821 JY8QFUQ01C2G78 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12822 JY8QFUQ01CEAMW productive (see comment) Homsap IGHV4-39*02 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctctggtgactccatTttccagtactagttattTactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 12823 JY8QFUQ01CD9B2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1071 99.54 216/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccgggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12824 JY8QFUQ01AFQVN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactcag 12825 JY8QFUQ01B6XNK unproductive (see comment) Homsap IGHV3-13*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - stop codons agcctctggattcacggttcagtaatacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12826 JY8QFUQ01BVH99 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgGttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12827 JY8QFUQ01ACFOO productive Homsap IGHV3-9*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSGGYTHNYFDYW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12828 JY8QFUQ01BQOMW unproductive Homsap IGHV4-61*02 F 911 90.5 200/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CASSTSF#LDHW out-of-frame + tctctgatggctccatcggcagtggtactcactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtgtctatgccactgggaaaaccgattacagcccctccctcaagagtcgcgtcaccatatcagtagacacggccaagaaccagttctacctgaccctgaggtctctgaccgccgcagacacggccatttattactgtgcgagtagcaccagtttttttggaccactggggccagggaacgctggtcaacgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca 12829 JY8QFUQ01BO6GI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + tctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 12830 JY8QFUQ01CIRW5 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 15 8.7.15 [1.17.38.11] CARAKKVRGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagcaaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12831 JY8QFUQ01AS3TX productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12832 JY8QFUQ01BHYWI unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 10 X 8.10.X [1.17.38.11] CVVDIPEVVWG#FDYW out-of-frame + ctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttgtgtgggggaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgatcatcgcctgcctggtccagggcttcttccccca 12833 JY8QFUQ01CQNEN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 793 84.93 186/219 nt 84.02 184/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRVKRFGSGNVLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); ggctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgAaagggccggttcaAccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 12834 JY8QFUQ01CK280 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 924 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggtggctccatgagcagtggtaattactgctggggctggggccgccagcCccccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgctgcctggtccagggcttcttccc 12835 JY8QFUQ01A1XYE productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12836 JY8QFUQ01A7G35 productive (see comment) Homsap IGHV1-8*01 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaaGcccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12837 JY8QFUQ01BK953 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12838 JY8QFUQ01CVT0D unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 12839 JY8QFUQ01AWT6X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcttccccgaaccggtgacggtgtcgtggcaactca 12840 JY8QFUQ01A9LRE No results 12841 JY8QFUQ01CR6CB productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-1*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARRQLALAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); tggatacaccgttatcacctactggatcgcctgggtgcgccaaatgcccgggaaaggcctggagttgatggggaGtcatctatcctggtgactctgagaccagatacagcccgtccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12842 JY8QFUQ01DXG9Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12843 JY8QFUQ01AQQCI productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12844 JY8QFUQ01CX7EK unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKNRGVGDG##WYFDFW out-of-frame - stop codons in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 86 to 88 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'AT' (2 nucleotides at position 209 to 210 in the user submitted sequence), (cause frameshift); tctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgATttagtttctgtgcgaaaaataggggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12845 JY8QFUQ01AGDUU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12846 JY8QFUQ01CGIGB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 792 84.79 184/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12847 JY8QFUQ01CK70G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12848 JY8QFUQ01B02KX productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12849 JY8QFUQ01A3JDG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggcCtggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctCccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12850 JY8QFUQ01DWPG0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12851 JY8QFUQ01B1P1S unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12852 JY8QFUQ01C1PBT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12853 JY8QFUQ01BMS0L No results 12854 JY8QFUQ01AUPO3 productive (see comment) Homsap IGHV3-7*01 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 10 8.7.10 [1.16.38.11] CGTGSGWEVEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcgccgttaatagtcattggatgaattgggtccgccaggctccagggaaggggctggaatggtggccaacatacaacaagatggagtgagaaaaactatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctctctattactgtgggactggcagtggctgggaagttgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12855 JY8QFUQ01BSXDM No results 12856 JY8QFUQ01CVV67 No results 12857 JY8QFUQ01C0UKA No results 12858 JY8QFUQ01DS988 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + cctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12859 JY8QFUQ01AIQ7B No results 12860 JY8QFUQ01AHOJP productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12861 JY8QFUQ01ATAPM No results 12862 JY8QFUQ01BTSOV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggcccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12863 JY8QFUQ01A8QLW No results 12864 JY8QFUQ01A0QIG productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARYGDYELGGDFW in-frame + tggaggcgccttcagcacctatagaatcatttgggtgcgacaggcccctggacaagggcttgagttgatgggagggatcgtccctatctttggcgcaccgaactacgcacagaagttccaggacagaatcaccattaccgcggacgaatccacgagcacggcctacatggagttgagtagcctgagatctgaggacacggccgtgtatttctgtgcgagatacggtgactacgaactcggcggtgacttctggggccagggaaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12865 JY8QFUQ01BMULR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + cctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgacgcctctgcagcacccagccagatgggaacgtgtcatcgctgcctggtccagggcttcttccc 12866 JY8QFUQ01DPITD No results 12867 JY8QFUQ01DSH2U unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 125 56.52 65/115 nt 8 10 X 8.10.X [1.17.2.X] null + No rearrangement found ctctggattcagctttagttactattggatgagctgggtccgccaggctcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12868 JY8QFUQ01AJP1M unknown (see comment) Homsap IGHV4-30-4*01 F, or Homsap IGHV4-30-4*02 F or Homsap IGHV4-30-4*03 F (see comment) 398 65.4 138/211 nt 10 7 X 10.7.X [1.17.35.X] null + No rearrangement found Low V-REGION identity (65,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgccctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 12869 JY8QFUQ01DFEAQ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 483 89.17 107/120 nt 88.33 106/120 nt 8 7 X 8.7.X [1.17.6.X] null - No rearrangement found in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgca 12870 JY8QFUQ01B0236 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 12871 JY8QFUQ01DQCT2 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-19*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARDIGSGWIDALHIW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattggccatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagatgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatattggcagtggctggattgatgctttacatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12872 JY8QFUQ01A6CNG productive Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12873 JY8QFUQ01BZ35D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 643 77.78 168/216 nt 77.31 167/216 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDIWAREWNDMAAFQMW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ccccggaatcattttcccagctatgtcatgagttgggtccgccaggccccagggaaggggctggaggtggtgcaggcaagcattagtGcagggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12874 JY8QFUQ01CLL4N productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 903 89.69 200/223 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 12 8.10.12 [1.17.38.11] CTITVRPDDYHDYW in-frame + ctctggagtcactttcactaacgtgtggatgagttgggtccggcaggctccagggaaggggccggagtgggttggccgtattaaaagggagactgagggggggacaatagactacgctgcacccgtgacagcaagattcaccatgtcaaaagatgattcaaaaaacacactatatctgcaaatgaacaacctgaaaatggaggacacagccgtgtattactgtaccataacagtccgaccggatgattaccatgactactggggccagggaaccctggtgaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctccagg 12875 JY8QFUQ01AZWXX unproductive (see comment) Homsap IGHV3-9*02 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CVKDKDKVGGPHWPLSH#FDFW out-of-frame + stop codons Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaaccccgaaaactttgccatgcactgggtccgacaagttccagggaagggcctgaagtgggtctcaggtataaattggaatggacgaaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccaatttggggactgaggacacggccttctatttttgtgtgaaagataaggacaaagtggggggtccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaaggactacttccccgaaccggctgacggtgtcgtggaactca 12876 JY8QFUQ01BU4RC unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTDRRGSDIPPQ#FDYW out-of-frame + stop codons ctctggatttagtttcaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaagctgatggtggggcggcagactacggtgcacccgtgagaggcagattcaccatctcaagagatgattcaagaggcacggtgtctctgcaaatgagcagcctgaaaaccgaggacacagccatctattattgtaccacagataggaggggttcggatattccacctcaattttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 12877 JY8QFUQ01BNHKI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12878 JY8QFUQ01CCVIK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 454 71.28 134/188 nt 6 8 X 6.8.X [X.17.31.X] null + No rearrangement found Low V-REGION identity (71,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtcatcgcctgcctggtccagggcttcttccccca 12879 JY8QFUQ01CUBKO productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12880 JY8QFUQ01DB4T3 No results 12881 JY8QFUQ01B34YK unproductive Homsap IGHV3-64*02 F, or Homsap IGHV3-64*04 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggccagggaaccctggtcaccgtctcctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12882 JY8QFUQ01DD6CC unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcag 12883 JY8QFUQ01BOQGM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12884 JY8QFUQ01AEZ8T unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.17.38.11] CAREVKYGDDTGGWFD#PG out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); agcgtctggattcaccttcagtgactctggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcacttatatggtatgatggatattataaacaacatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattactgtgcgagagaggtgaaatacggtgacgacacgggggggtggttcgacccctgggggccagggaaccctggtcaccgtctcatcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12885 JY8QFUQ01CCRGO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12886 JY8QFUQ01DCA4Q unproductive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKRLAEQRLVPF*G#W out-of-frame - stop codons cctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctttcccca 12887 JY8QFUQ01BTGBR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12888 JY8QFUQ01A1WLI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12889 JY8QFUQ01CY3ZT productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.16.38.11] CSKDTFGREDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 2 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) cctctggattctccgtcagtaattactggatgcactgggtccgccaggctccagggagggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12890 JY8QFUQ01B8J1O unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F (see comment) 623 80.31 155/193 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found Low V-REGION identity (80,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaaggactacttccccgaaccggtgacggtgtcgtggaactca 12891 JY8QFUQ01CAYIT productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-9*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGGVDILTGFYDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ttctggatacagctttggcaccgcctggctcggctgggtgcgccagacgcccgggaAaaggcctggagtggatggggaccatccatcctgctgactctgatacaaaatacagcccgtccttccagggccaagtcaccatctcggtcgacaggtccatcaacaccgcctacctgcagtggagcagcctggaggcctcggacaccgccatgtatttctgtgcgcggggaggagtcgatattttgactggtttctatgatgctttcgatatctggggccaagggaccatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12892 JY8QFUQ01DCFT6 productive Homsap IGHV3-9*01 F 892 89.95 197/219 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARTYGDHDGMDVW in-frame - gtctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtggtaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12893 JY8QFUQ01BPWQZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtgGgtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12894 JY8QFUQ01DUY13 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 97 52.67 69/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 12895 JY8QFUQ01CYMW5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'AT' (2 nucleotides at position 85 to 86 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacgaaATtcaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12896 JY8QFUQ01CU8KI unproductive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + stop codons ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgtaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12897 JY8QFUQ01DRKCQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [2.16.38.11] CATAPLGSSNWDAFEMW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'GGTCGTCAT' (9 nucleotides at position 84 to 92 in the user submitted sequence), (do not cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gcctctggattcacccttaggaattatgccatgagctgggtccgccaggctccagggaaggggctgagtgggtctccgctattGGTCGTCATggtggtagtggcggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacatttccgagaacacgctgtatgtgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgacagctcccctggggagcagcaactgggacgcttttgagatgtggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12898 JY8QFUQ01BEGXL productive Homsap IGHV3-11*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFDYW in-frame - ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacggccacgtattattgtgtgaggcgggtctggggatatagttatggttccgtttcgtattacttcgactactggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12899 JY8QFUQ01A1963 productive (see comment) Homsap IGHV3-64*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 7 8 10 7.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcatttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 12900 JY8QFUQ01AUQ13 No results 12901 JY8QFUQ01B2NTW productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 869 90.91 190/209 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 7 11 7.7.11 [X.17.38.11] CAISSGFYSTGYW in-frame - ggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12902 JY8QFUQ01DK7D4 No results 12903 JY8QFUQ01BJIWU No results 12904 JY8QFUQ01BMDY0 unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F (see comment) 458 67.91 146/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (67,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12905 JY8QFUQ01B956I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12906 JY8QFUQ01CNCW4 productive (see comment) Homsap IGHV1-24*01 F 970 95.31 203/213 nt 94.84 202/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgCatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagcccaaggtcttcccgctgagcctctgcaagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12907 JY8QFUQ01BBZDL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + tcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12908 JY8QFUQ01CGPP0 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 165 75.0 45/60 nt 8 X X 8.X.X [1.10.X.X] null - No rearrangement found gctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca 12909 JY8QFUQ01A1BT3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagttacttctggagttggatGccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12910 JY8QFUQ01BMCAM productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12911 JY8QFUQ01BZ7IE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + ctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggct 12912 JY8QFUQ01DWONA productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 782 83.48 187/224 nt 83.04 186/224 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cctctgggttcGattttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12913 JY8QFUQ01C3SV7 unproductive Homsap IGHV4-61*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 22 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtaCTGGTTattactactggagctggatccggcagtccgccgggaagggattggaatggattgggcgcatgtctgccagaggggacagcaactacaaccccGtccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttttccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg 12914 JY8QFUQ01CMFGL No results 12915 JY8QFUQ01DUT18 No results 12916 JY8QFUQ01ALZGA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 742 82.87 179/216 nt 81.94 177/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 7 8 15 7.8.15 [1.17.38.11] CARYRVGDSLYYGLDGW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 58 of V-REGION: 'CAC' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagCACtagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12917 JY8QFUQ01B4FQA unproductive Homsap IGHV3-48*02 F 971 94.88 204/215 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [0.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - ctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12918 JY8QFUQ01BY80F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12919 JY8QFUQ01A30CD productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12920 JY8QFUQ01B77RX No results 12921 JY8QFUQ01BUGW0 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gtctggattcacgtttagtagAttttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12922 JY8QFUQ01ANAE8 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 198 93.33 42/45 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found ctctggattcaccttcagcaagtatgccatgagctgggtccgcca 12923 JY8QFUQ01BO7N4 productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 12924 JY8QFUQ01CCLO8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - tctggagttcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12925 JY8QFUQ01CFIZH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggcccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 12926 JY8QFUQ01A7TII No results 12927 JY8QFUQ01A4MST unproductive Homsap IGHV3-11*01 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRDYYYYGMDV## out-of-frame + in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 96 to 98 in the user submitted sequence), (do not cause frameshift); cttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggcccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 12928 JY8QFUQ01CEVA5 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMFYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); catctggattcaccttcagttcttatagtgtaaAactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 12929 JY8QFUQ01BGO68 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12930 JY8QFUQ01CKQHV productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcagg 12931 JY8QFUQ01C9R55 productive Homsap IGHV3-48*04 F 963 94.01 204/217 nt Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARRGTQLGYCASPSCPTDLW in-frame + ctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattctccatctccagagacaacgccaggaactcagtggatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcgaggaggggaacacaactgggatactgtgctagccctagctgcccaactgacttgtggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttc 12932 JY8QFUQ01B7MFV productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12933 JY8QFUQ01A2LM7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [2.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); gggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatCggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12934 JY8QFUQ01APK90 unproductive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY## out-of-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12935 JY8QFUQ01BF8LB No results 12936 JY8QFUQ01BQ2G8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASDLGGQKSYW in-frame - gcctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12937 JY8QFUQ01DFSO3 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGVLFMGDY## out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggGCctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccgggggggtactttttatgggggactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctggggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12938 JY8QFUQ01ASUCZ productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 824 86.7 189/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-17*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARHSGALATGSQNWFDPW in-frame - cgtcgggatttaggtttgatgattttggcatgagctgggtccgccaagttccagggaagggcctggaatgggtctctggtagtgactggagtggtggaagaacaggttatggtgactctgtgaagggacgattcatcatctccagagacaacgccaagaactccctatatctacaaatgaacgatctgcgagccgatgacacggccgtctattattgtgcgcgacatagtggggcgctggctactgggtctcagaactggttcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12939 JY8QFUQ01A7CQO No results 12940 JY8QFUQ01CEGC4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggacCtccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12941 JY8QFUQ01A15L6 productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.0 187/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtCgggggtgtcgactacaaccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12942 JY8QFUQ01DR1MK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12943 JY8QFUQ01BV9QC unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 12944 JY8QFUQ01AFKQK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12945 JY8QFUQ01DM4PH No results 12946 JY8QFUQ01BB9QJ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 680 78.9 172/218 nt 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagACcccccggggaaggggActggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 12947 JY8QFUQ01AJEGM No results 12948 JY8QFUQ01CFD3R No results 12949 JY8QFUQ01BGY6V productive Homsap IGHV4-31*06 F 974 93.64 206/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame - tctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagggaagggcctggagtggattgggtacatctattacagtgggagcgcctactacaacccgtccctcaagagtcgagttgccatatcaatagacacgtctaagaaccagttctccctgaacttgagttctgtgactgtcgcggacacggccgtttattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12950 JY8QFUQ01CIQ3H productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12951 JY8QFUQ01AJV3S productive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + tctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 12952 JY8QFUQ01AVA4S No results 12953 JY8QFUQ01AZFDY No results 12954 JY8QFUQ01BF83C No results 12955 JY8QFUQ01BBG80 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CAKRPPGTIDRW in-frame + cctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccgattcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12956 JY8QFUQ01CAI7Q productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 889 88.74 197/222 nt 87.84 195/222 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 10 7 16 10.7.16 [2.17.38.11] CTNDHSMAVSAKHAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gtctctggtgcctccGatgagcaCgtagtgcatactactggggctgggtccgccagacccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12957 JY8QFUQ01BGMLL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacac 12958 JY8QFUQ01BNGZQ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12959 JY8QFUQ01AVMMR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 12960 JY8QFUQ01AY632 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12961 JY8QFUQ01C8750 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 12962 JY8QFUQ01BA5ST productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 3 8 8 19 8.8.19 [1.16.38.11] CARIIPYDPRTDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) cctctggattcagcttcagtaattatatcatgacttggtccgccaggcccagggaaggggctggagtgggtctcatctattagtggaagtagtagtaacatattctacgcagactcaatgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaataatcccgtatgacccgaggaccgactattattactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 12963 JY8QFUQ01A32N8 No results 12964 JY8QFUQ01B2AZY No results 12965 JY8QFUQ01AE9M1 productive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12966 JY8QFUQ01CH7KP productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1016 95.09 213/224 nt 94.64 212/224 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-2*01 F 1 8 10 13 8.10.13 [1.17.38.11] CTSSQDQLITSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctgggttcaccttcagtgtctctcctatgcactgggtccgccaggcttccgggaAaagggctggagtgggttggccgtattagagacaaagctaacacttacgcgacaacatatgctgcgtcggtgaaaggcaggttcaccatcgccagagatgattcaaagaacacgacatatctgcaaatgaacagcctgaaaatcgaggacgcggccgtgtattactgtactagttctcaggaccagttgataacgtcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12967 JY8QFUQ01CQPJ6 unproductive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggatttaGgctttagaaccttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12968 JY8QFUQ01APV5G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [2.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame - agcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggttcagggcttcttccccca 12969 JY8QFUQ01BS42T No results 12970 JY8QFUQ01CINRZ productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12971 JY8QFUQ01BU3DY productive Homsap IGHV3-11*01 F 981 94.93 206/217 nt Homsap IGHJ6*01 F 252 88.89 56/63 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRYWGSYYYYNGLDVW in-frame + ctctggattcaccttcactgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtggtggtagaaccattgcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatattggggcagctactattactataacggtctggacgtctgggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 12972 JY8QFUQ01B2GL4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 12973 JY8QFUQ01DN9QX No results 12974 JY8QFUQ01CWDBY unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 88.69 196/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggGAaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggccctatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 12975 JY8QFUQ01C1RZA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgntgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 12976 JY8QFUQ01C7LPO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgacgggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 12977 JY8QFUQ01C80HI productive Homsap IGHV4-4*07 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - tgtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12978 JY8QFUQ01BCD9X productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12979 JY8QFUQ01BYE5A productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12980 JY8QFUQ01CP7A0 No results 12981 JY8QFUQ01DGG26 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12982 JY8QFUQ01DC9TA productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12983 JY8QFUQ01DXHGU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 841 87.96 190/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12984 JY8QFUQ01B030E unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 165 75.0 45/60 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found gctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca 12985 JY8QFUQ01CPNBB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDCDSGECNFDY## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccaagggaaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12986 JY8QFUQ01CB9YO No results 12987 JY8QFUQ01B30T6 unknown (see comment) Homsap IGHV3-48*01 F 1041 97.27 214/220 nt 96.82 213/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); gcctctgggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacaGttagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12988 JY8QFUQ01C8IHX productive Homsap IGHV3-13*01 F 976 94.91 205/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12989 JY8QFUQ01A8XJC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.16.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctgagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12990 JY8QFUQ01BTEZT productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12991 JY8QFUQ01APCHX productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12992 JY8QFUQ01BWALA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacaGacccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12993 JY8QFUQ01AUUNC unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 12994 JY8QFUQ01CZZGJ productive (see comment) Homsap IGHV3-7*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12995 JY8QFUQ01B9OTU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 12996 JY8QFUQ01AQ20J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 12997 JY8QFUQ01DS3UV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 1 10 7 12 10.7.12 [1.17.38.11] CAWGWFGLNYFDYW in-frame + tctctggtggctccgtcagaagtaccagttactactggggctggatccgccagcccccagggaaggggctggagtggattagtaacattcattctagtggaaccacctactacaacccgtccctcaacagtcgagtcaccatgtccgtaaacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggctgtatattactgtgcatgggggtggttcggactgaactactttgactactggggcccgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 12998 JY8QFUQ01ADUCB unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAGAEAGLLTY## out-of-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgacgtactggggccctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 12999 JY8QFUQ01CB61D productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13000 JY8QFUQ01B1GMB No results 13001 JY8QFUQ01BXO6Y productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13002 JY8QFUQ01DLL4K unknown (see comment) Homsap IGHV3-74*03 F 116 54.14 72/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13003 JY8QFUQ01BGM4F productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13004 JY8QFUQ01BCC02 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 854 87.05 195/224 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13005 JY8QFUQ01AND5U productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 744 82.19 180/219 nt 81.74 179/219 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 6 15 10.6.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) tctcgggtggttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13006 JY8QFUQ01CLIT1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13007 JY8QFUQ01CCVOC unproductive Homsap IGHV1-2*02 F 777 85.05 182/214 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [0.17.38.11] CARVRGIVANKTLPR#ALDVW out-of-frame - tggatacaccttcaccggctactatttgcactgggtacgacaggcccatggacacggggttgagtctctggggtggctccaccctgaaagcggcagcacgaattatgcagagaagtttgggggcagggtcaccatgacccgggacacgtccatcagcactgcctacatggagctgaaaagtctaacactggacgacacggccgtctattactgtgcgagagttcggggcatagtggcgaacaaaaccctcccgcggggctttggatgtctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13008 JY8QFUQ01APR9P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDPW in-frame + tctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13009 JY8QFUQ01A0LAJ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 845 86.61 194/224 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTWDSTGYFRLTW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13010 JY8QFUQ01AXVTD unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 130 52.51 94/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found tctggattcaccttcagtagctatggcatacactgggtccggcaggctccagggagggggctggagtgggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13011 JY8QFUQ01ADGJZ productive (see comment) Homsap IGHV3-11*01 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctgggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggGggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13012 JY8QFUQ01B9HCQ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 873 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARVRDGSKQPPDWW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcatgttcagtgcctatggcatgaactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagcggtggcacttacatatcatacgcaaactcagttaagGgggcgattcaccgtntccagagacaacaccaagaattctctgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagtcagagatgggtccaagcaacccccggactggtggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13013 JY8QFUQ01CCL9J productive (see comment) Homsap IGHV3-11*01 F (see comment) 770 83.94 183/218 nt 83.49 182/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVRCSGNTCGAFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggattcagcttaagtgactactacatgacctgggtccgccaggccccagggaagggactggagtggctcgcctacattagtcgaactgatgattccgtatattccgcagagtctgtggtgggccgattcaccgtctccagggacaacgtccaaaactcactgTtttttgcagatgattggcctgagagacgaggacacggccgtatattactgtgcgagagtccgctgtagtggtaatacctgcggggcttttgatttgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13014 JY8QFUQ01CCXME productive Homsap IGHV3-9*01 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame - tctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13015 JY8QFUQ01BHE4O No results 13016 JY8QFUQ01C2MRC productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13017 JY8QFUQ01C0SYV productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13018 JY8QFUQ01CPDTA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13019 JY8QFUQ01COJ8F productive (see comment) Homsap IGHV3-66*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtagcagcttcatgActtggggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaaggGgccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13020 JY8QFUQ01A0HSP No results 13021 JY8QFUQ01BHDAI No results 13022 JY8QFUQ01DF8VY unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 625 93.01 133/143 nt 8 8 X 8.8.X [1.17.13.X] null - No rearrangement found gctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctcc 13023 JY8QFUQ01C2B9H unknown (see comment) Homsap IGHV3-7*02 F 118 60.24 50/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13024 JY8QFUQ01ALWGF unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDWGGSFDRY#FDYW out-of-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattatttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13025 JY8QFUQ01CGZWG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacgggggggactgacacagcctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13026 JY8QFUQ01C2DJG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 951 92.73 204/220 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13027 JY8QFUQ01B3M80 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 645 83.15 153/184 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.15.38.11] DSRNPRV# out-of-frame - Low V-REGION identity (83,15% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggggtccgccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13028 JY8QFUQ01CDGF0 No results 13029 JY8QFUQ01BCMK8 No results 13030 JY8QFUQ01CXEJW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CTKDTFWER#DYW out-of-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgttttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13031 JY8QFUQ01A79R5 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13032 JY8QFUQ01CTWUZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-9*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGGVDILTGFYDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gttctggatacagctttggcaccgcctggctcggctgggtgcgccagacgcccgggaaaAGgccctggagtggatggGggaccatccatcctgctgactctgatacaaaatacagcccgtccttccagggccaagtcaccatctcggtcgacaggtccatcaacaccgcctacctgcagtggagcagcctggaggcctcggacaccgccatgtatttctgtgcgcggggaggagtcgatattttgactggtttctatgatgctttcgatatctggggccaagggaccatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13033 JY8QFUQ01CWYEB No results 13034 JY8QFUQ01CAFR8 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 894 88.79 198/223 nt 87.44 195/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [2.17.38.11] CTNDHSMAVSAKHAFDV## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tgtctctggtgcctccGatgagcaCgtagtgcatactactggggctgggtccgccagaAcccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttgggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13035 JY8QFUQ01B2QJ5 No results 13036 JY8QFUQ01CR0DV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13037 JY8QFUQ01BE590 productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F (see comment) 881 84.77 206/243 nt 84.36 205/243 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 93 of V-REGION: 'CG' (2 nucleotides at position 208 to 209 in the user submitted sequence), (cause frameshift); accctcaccctgacctgcgacttctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccCGacatggggcccctnagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13038 JY8QFUQ01BZLGF unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 13039 JY8QFUQ01BAFYU No results 13040 JY8QFUQ01DGAGY No results 13041 JY8QFUQ01AWE3U productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13042 JY8QFUQ01BJR0T productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CAKDRLDSSGHYYHGVYYFGMDVW in-frame + cctctggatttagttttgaaaactatggcatgcattgggtccgccaggctccaggcaagggcctggaatgggtggcggttatatcatatgatgcaagtaacaaatattatgcagacgccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatcttcaaatgatcggcctgagagctgaggacacggctaaatactactgtgcgaaagatcgccttgacagcagtggtcattactaccacggggtctactacttcggaatggacgtctggggcccagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca 13043 JY8QFUQ01CT5TN unknown (see comment) Homsap IGHV3-7*03 F (see comment) 208 54.79 120/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (54,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13044 JY8QFUQ01DL2SK productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 626 76.15 166/218 nt 75.23 164/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,15% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'TGG' (3 nucleotides at position 31 to 33 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcgatTGGgtggaacttgggtccgccagaAcccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13045 JY8QFUQ01DAD3P productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 930 91.03 203/223 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 7 17 8.7.17 [4.17.38.11] CARDSGSSEYTRYDAQDVW in-frame + ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttgccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgt 13046 JY8QFUQ01DXGMS productive (see comment) Homsap IGHV4-59*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-22*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARDQGVVANYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtgattactactggaactggatccggcagcccccagGggaagggactggagtggattgggtatgtctatcacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgttcaagaaccaattatccctgaaggtgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagatcaaggcgtcgtggctaattactactactacggtatggacgtctggggccaaggggccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgtctgcctggtccagggcttcttccccccg 13047 JY8QFUQ01C5RV8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcacttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtatttgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggcccagggagccctggtctccgtctgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaaccgtggtcatcgcctgcctcgtccagggcttcttccccca 13048 JY8QFUQ01CB45P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 879 88.64 195/220 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDHSMAVSAKHAFDVW in-frame + ctctggtgcctccatgagcagtagtgcatactactggggctgggtccgccagacccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13049 JY8QFUQ01BDS19 productive Homsap IGHV3-72*01 F 876 88.34 197/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - ctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13050 JY8QFUQ01ACXCD No results 13051 JY8QFUQ01A02GN unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 13052 JY8QFUQ01BGOHU productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13053 JY8QFUQ01BLEOZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13054 JY8QFUQ01A9DGQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13055 JY8QFUQ01AIGXY productive (see comment) Homsap IGHV3-7*01 F 963 94.01 204/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.16.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) acctctggattGcacctttagtaaccattggatgaactgggtccgccaggctccagggaagggctgagtgggtggccaacataatgccagatggaggtgagaaAattctatgtggactctgtgaaggGgccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13056 JY8QFUQ01C6FU9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 766 83.56 183/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13057 JY8QFUQ01B0JWX productive Homsap IGHV4-61*02 F (see comment) 677 78.73 174/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARDRRRSIAGARHFDSW in-frame - Low V-REGION identity (78,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggccccaccatcgatgatggtgatttgtggacctggatccggcagcccgccggcaagggactggaatggatcggttatgtctatgatgggcggggcaccaactccaacccctccctccggagtcgcgttaccctgtcacaagacacctcaaacaatcagttcttcttgaggttgaagtctgtgaccgcctcagacacggccgtctattactgtgcgcgagaccgccgtaggtcgattgccggagcgagacactttgactcctggggccagggaatcctggtcaccgtcgccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13058 JY8QFUQ01CTHRK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13059 JY8QFUQ01AXE56 productive (see comment) Homsap IGHV3-9*01 F (see comment) 778 84.72 183/216 nt 84.26 182/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13060 JY8QFUQ01BI6RE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ5*01 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.16.38.11] CARDGDYYDSSGNFLGHSFDI## out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cgtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaagggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacgactccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagagatggagattattatgatagtagtggtaatttcctgggacattcttttgatatctgggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13061 JY8QFUQ01CM936 No results 13062 JY8QFUQ01AU7DL No results 13063 JY8QFUQ01DH1JU productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.38.11] CAREGGRGYDMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 103 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcatttatcactgataggggtagtaccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 13064 JY8QFUQ01BR9V1 productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagcatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13065 JY8QFUQ01CEG6J productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13066 JY8QFUQ01CF3IX productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 13067 JY8QFUQ01AC5UE No results 13068 JY8QFUQ01CVFZR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13069 JY8QFUQ01CDO5X unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGQQLRDFDY# out-of-frame + tggatacaccttcaccagctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13070 JY8QFUQ01BI3SN productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 211 88.68 47/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIRLGDWCFDIW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctggggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13071 JY8QFUQ01C49B2 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 2 8 7 X 8.7.X [1.17.38.11] CARAPRTATLLDP#W out-of-frame + in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagccCcccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaaccCcctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgaccccgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13072 JY8QFUQ01DDSRU unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [0.17.38.11] CARELGGSGTCGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactgggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 13073 JY8QFUQ01BI2G2 productive (see comment) Homsap IGHV3-7*01 F 1012 96.76 209/216 nt 96.3 208/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13074 JY8QFUQ01B6L9D productive (see comment) Homsap IGHV3-48*01 F (see comment) 744 83.89 177/211 nt 82.94 175/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) tggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13075 JY8QFUQ01DNLTG No results 13076 JY8QFUQ01CWWNH productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13077 JY8QFUQ01B82C5 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYD*GEYAMDVW in-frame + stop codons gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactagggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13078 JY8QFUQ01CF0TC productive Homsap IGHV3-66*02 F 894 91.12 195/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVGATVAFQYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattctttataggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtgggagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13079 JY8QFUQ01DHNOA No results 13080 JY8QFUQ01AZFMI productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgt 13081 JY8QFUQ01DQYPT No results 13082 JY8QFUQ01DSMPJ No results 13083 JY8QFUQ01CP7W8 No results 13084 JY8QFUQ01CWMFJ No results 13085 JY8QFUQ01CDQ8D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 872 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggnccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13086 JY8QFUQ01ASJZS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13087 JY8QFUQ01A1EAJ productive (see comment) Homsap IGHV3-7*03 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13088 JY8QFUQ01DB22E productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13089 JY8QFUQ01BCH7Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13090 JY8QFUQ01CVYUM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 989 93.75 210/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTDPRYFWGSGFDYW in-frame - cctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13091 JY8QFUQ01DB3M9 No results 13092 JY8QFUQ01C0IFS No results 13093 JY8QFUQ01CK6XV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame + tctctggtgactccttcagaactcactactggagttggattcgacagcccccggggaggagattggaatggattggcaatatatattatattgggaccaccaactacaacccctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 13094 JY8QFUQ01A3NWZ unknown (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13095 JY8QFUQ01AJOJR unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRGGSQWGLQVG#FDYW out-of-frame - stop codons ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagaggggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13096 JY8QFUQ01AQPJX No results 13097 JY8QFUQ01B2B76 No results 13098 JY8QFUQ01B0M02 No results 13099 JY8QFUQ01DS4IG unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 994 93.78 211/225 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [2.17.38.11] CTTGGWN*L##W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) acctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcgaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacaggggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13100 JY8QFUQ01BVEA2 productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) ctctggattcagctttagttattattggatgagctgggtcgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13101 JY8QFUQ01AIAUO unproductive (see comment) Homsap IGHV3-7*01 F 816 85.91 189/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARGSYYYYDTNGDYW in-frame - stop codons ctctggatttgacctttgacaaattattgggatgagctgggtccgccaggctccagggagggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13102 JY8QFUQ01DI8RP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13103 JY8QFUQ01CP5IA productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [2.16.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gtctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaaggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13104 JY8QFUQ01AQZCF productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.16.38.11] CASVVTINDNGDYTWAFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcaataattacttctggacctggatccgccagtcccagggaaggggccggagtggattggggaaatcaatcatagtggtagcaccaactacaatccgtccctcaagagtcgagtcaccatctcaatagacacgtccaagatccagttctccctgcagctgagctctgtgaccgccgcggacacggctgtctattactgtgccagtgtagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccacccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13105 JY8QFUQ01BN4SH No results 13106 JY8QFUQ01CGSXJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13107 JY8QFUQ01CPWQZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtcaccgtctcctcaggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13108 JY8QFUQ01CYV8D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13109 JY8QFUQ01AFQ4V unproductive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGY*GIYFFDYW in-frame + stop codons ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttactgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttgccccctggcgccctcgctccaggagcacctccgacgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13110 JY8QFUQ01B56AV unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 454 72.63 130/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13111 JY8QFUQ01A0R5L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 848 91.13 185/203 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 4 8 11 4.8.11 [X.17.38.11] CARFGPLTRPDYW in-frame - tatcaacttatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13112 JY8QFUQ01C91GT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPLYNWN#YFYYYGMDVW out-of-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 13113 JY8QFUQ01A4HOH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13114 JY8QFUQ01C12XQ unproductive Homsap IGHV3-9*01 F 1008 96.31 209/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGIAVAASHESTFRLL# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattttgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaggatagtctatgcggactctgtgaagggccgattcaccatctccagagacaacgcccagaactccctgtatctgcaaatgaacagtctgggtactgaggacacggccttgtattactgtgcaaggggtatagcagtggctgcctcccacgagtcgacttttcgactactggggcccaggggaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13115 JY8QFUQ01DA1KP productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 808 86.85 185/213 nt 85.92 183/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 12 8.7.12 [0.17.38.11] CARRSTSGDKFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift) tggagggaacttcaacaattatggtttcagctgggtgcgacaggcccctggacaaggccttgagtggatgGggagaaatcatcccttttttggaacatcaaaatatacacagaaattccagggcagactctccattaccgcggacgaatccacgagcacagcctttatggacttgagtggcctgagatctgaggacacggccgtctattattgtgcgagaaggtctactagtggggataaatttgacttctggggccagggaagccaggtcaccgtctcctcagcctccaccaagggcccaatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag 13116 JY8QFUQ01A4AB0 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13117 JY8QFUQ01B190C No results 13118 JY8QFUQ01C91ZM unproductive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [1.17.38.11] CARNTNYGGNSGDYFDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggcccaagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13119 JY8QFUQ01DIM4J productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 789 84.55 186/220 nt 83.64 184/220 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-16*01 F 2 8 10 13 8.10.13 [0.16.38.11] CSTGGPNGYESTYPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ctggattGcaccttcaatatcaagtggatgagttgggtccgccaggctccgggaaggggctggagtgggttggccgcatcaagagcacctctgatggtgggacaacagactccattgcacacgtcaaagacagattcatcatctcaagagatgattcaagaaatacactgtacttacaaatgaacaacctgagagtcgaggatacaggcgtctattattgttccacaggagggccaaatggttatgagtctacctatccctggggcccgggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13120 JY8QFUQ01BHB9O unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F 130 67.74 42/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKYVEGWS*YGGLL##SYAMDVW out-of-frame + stop codons in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggaggggcgtggaAGgtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatgatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13121 JY8QFUQ01C3EMZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 13122 JY8QFUQ01CNC9O productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13123 JY8QFUQ01BWY7M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEGTTGVYYVDHW in-frame - tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtactactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13124 JY8QFUQ01BT1EX No results 13125 JY8QFUQ01CQQFU unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRRGMVAGRYDAFDI# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctgggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13126 JY8QFUQ01C157F unproductive Homsap IGHV4-61*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatTttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13127 JY8QFUQ01AX6P6 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactggtgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13128 JY8QFUQ01CEBII unknown (see comment) Homsap IGHV1-2*02 F 487 86.72 111/128 nt 8 8 X 8.8.X [0.17.9.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg 13129 JY8QFUQ01CGQ43 unproductive (see comment) Homsap IGHV4-59*03 F 915 92.89 196/211 nt 91.94 194/211 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 X 8.7.X [0.17.38.11] CARGHF***WLFQP#LDHW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 44 to 45 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 88 to 93 in the user submitted sequence), (do not cause frameshift); tggtgtctccatcagtagtttctactggagttggatgaggcagGCcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacatttttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13130 JY8QFUQ01AMPPP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13131 JY8QFUQ01CPBR4 productive Homsap IGHV3-7*03 F 837 87.56 190/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13132 JY8QFUQ01DTGK2 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKAYDDVLTSYYIAAFIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgccatgcattgggtccgccaggctccaggcaaggggccggagtgggtggcagttatatcatatgatggaagtcataaagactatgcagcctccgtgaagggccgattcaccatctccagagacaattccaagagtacgttgtatctgcaaatgaacagcctgagacctgaggacacggctttatattcctgtgcgaaggcatatgacgatgttttgacttcttattacatagcagcttttattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13133 JY8QFUQ01CCCXG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13134 JY8QFUQ01ABG0T productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 7 8 13 7.8.13 [1.16.38.11] CVSDRELHYQHLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) gtctggattcaactcaatagttttggcatgcactgggtcgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacaacggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13135 JY8QFUQ01BI9PN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13136 JY8QFUQ01BALK4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKLGGRRWL#WYFDFW out-of-frame + in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); cctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaaattagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13137 JY8QFUQ01AGZEC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13138 JY8QFUQ01CIXDK productive Homsap IGHV3-11*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARVKYSSSWSSILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcattcattagtagtcctggtatcaggagtttctacgcagactctgtgaagggccgattcactatttccagggacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgaggacacggccatatattactgtgcgagagtgaaatatagcagcagctggtcctcaatccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13139 JY8QFUQ01AMY1J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgt 13140 JY8QFUQ01B5AY8 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13141 JY8QFUQ01BIQEK productive Homsap IGHV3-7*01 F 918 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CSRHGGYTRLYNQNVYLDYW in-frame - ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaaaataaacccagacggaagtgagaaatactatgtggactctgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgctcgagacatggaggttacacgagactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13142 JY8QFUQ01DM5WF productive Homsap IGHV1-8*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARVWGVAFTGVWNYW in-frame - tggatacaccttcgccaattttgatatccactgggtgcgacaggccactggacaagggcttgagtggctgggatggatgcaccctaatagtggtaatacagtctatgcacagaagttccagggcagagtcaccatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagatctgaagacacggccatatattactgtgcgagagtctggggagtagcattcactggggtgtggaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13143 JY8QFUQ01AZH44 No results 13144 JY8QFUQ01C8AT8 unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*03 F (see comment) 259 69.91 79/113 nt 8 8 X 8.8.X [0.17.4.X] null - No rearrangement found Low V-REGION identity (69,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13145 JY8QFUQ01CUK8E productive (see comment) Homsap IGHV4-61*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcGatcgcacgcaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13146 JY8QFUQ01AV2DS No results 13147 JY8QFUQ01BLJZD productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13148 JY8QFUQ01DASRD No results 13149 JY8QFUQ01DOPR7 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13150 JY8QFUQ01BYO1I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVMREHYYGAGNYPWGEWKSG in-frame + ctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccatttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctggggggaatggaagtctggggccaggggaccacggtgcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 13151 JY8QFUQ01AQOEM productive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDHIWAFDFW in-frame + cctctggattcaccttcagtgactatagcatgaactgggtccgccagactccagggaagggggtggagtggatttcatacatcggccgtggtggtgatgggatatactacgcagactctgtgaagggccgaatcaccatctccagagacaatgccaagaactcactttttctgcaaatgaacaccctgagagacgacgacacggctgtgtattactgtgcgagagaccacatttgggcttttgatttctggggccaagggacaaaggttaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13152 JY8QFUQ01ACD8U productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 2 10 7 11 10.7.11 [1.17.38.11] CAGREVSGPFDFW in-frame - tctctggtggctccatcaagaggagtagttattactggggctggatccgccagcccccagggaaggggctggagtggattgggactatctattatagtgggagcacgtactacaactcgtccctcgagagtcgagtcaccatgtccgcagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtctattactgtgcgggacgagaagtgtcaggcccgtttgacttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13153 JY8QFUQ01AY96B productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13154 JY8QFUQ01CBKYC productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13155 JY8QFUQ01DJGC1 productive Homsap IGHV3-7*01 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - gcctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13156 JY8QFUQ01AIR5Z unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGL*QWL##DFDCW out-of-frame + stop codons cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13157 JY8QFUQ01CK3ME No results 13158 JY8QFUQ01BTBFG unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 13159 JY8QFUQ01AWJG8 productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame - tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgcttcaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13160 JY8QFUQ01C117N No results 13161 JY8QFUQ01DU9XY unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKR*LW#YYFDQW out-of-frame + stop codons in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctctggattcacctTttagtaaccattggatgaactgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacgatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 13162 JY8QFUQ01CCDYP No results 13163 JY8QFUQ01CBH7Q No results 13164 JY8QFUQ01BSBL1 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcgggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13165 JY8QFUQ01COT6C unproductive (see comment) Homsap IGHV4-39*02 F 912 90.13 201/223 nt 89.69 200/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 X 10.7.X [2.17.38.11] CARGHTNFWSGYSG#DYW out-of-frame - stop codons in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tctctgggtgactcccatttccagtactagttattactggggctgggtccgccagcccccagggaaagggctggagtggattCgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaggccatacgaatttttggagtggttactcgggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13166 JY8QFUQ01BA5IW No results 13167 JY8QFUQ01B5ITM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13168 JY8QFUQ01AQNL3 unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFF##YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13169 JY8QFUQ01B2N1Y No results 13170 JY8QFUQ01AY9NB productive Homsap IGHV3-30*10 F 896 90.37 197/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CARDVTTTVVVVVTLGAFDLW in-frame - cctctggattcagcttcactaaatatcctatacactgggtccgccaggctccaggcaagggactagagtgggtggcacttatatcatttgatggaactaataaatactacacagactccgtgaagggccgattcaccatctccagagacaattccaagaacacagtctttctgcagatgaacagtctgacaactgaagacacggctgcttattactgtgcgagagatgtgactactacggtggtagtagtcgtcacacttggagcttttgatctctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 13171 JY8QFUQ01CY32W unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 644 77.06 168/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13172 JY8QFUQ01B4K2Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13173 JY8QFUQ01CKRGV productive Homsap IGHV3-9*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CAKATTAWYSGGLDVW in-frame + cctctggattcaactttgatgattacggcatgcactgggtccggcaacgcccagggatgggcctggagtgggtcgcaggtattagttataataatggccacaaagaatatgcggactctgtgaggggccgattcaccatctctagagacaacgccaggaagtccctgtatctgcagatggacagtctgagagttgaggacacggccttgtattattgtgcaaaggctacaactgcctggtattcaggcggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13174 JY8QFUQ01DJDE8 No results 13175 JY8QFUQ01A0OC8 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.37.11] CAKSPSQVGYYLDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 137 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacctTttggcatgcactgggtccgccaggctcccggcAaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcacatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13176 JY8QFUQ01DKGHA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CAKGPHQYYFDYW in-frame + ctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13177 JY8QFUQ01AVB4I productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSRSPANW in-frame + ctctggattcagttttagtacctattggatgagctgggtccgccaggctccagggaaggggctggaatgggtggccaccataaacgaggatggaagtgacagaacctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaattcattgtatctacaaatgaatagcctgagaaccgacgacacggctcgatattactgtgcgacgcgtagtagaagtccggcgaactggggccagggaagcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 13178 JY8QFUQ01CALIR No results 13179 JY8QFUQ01BZ7VC unknown (see comment) Homsap IGHV3-11*01 F (see comment) 458 67.91 146/215 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found Low V-REGION identity (67,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13180 JY8QFUQ01AWJE7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); cctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccaggggaggggctggGagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13181 JY8QFUQ01A6Q87 productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13182 JY8QFUQ01BESKE productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13183 JY8QFUQ01AX3ZS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13184 JY8QFUQ01DIJLD productive (see comment) Homsap IGHV4-4*07 F 827 87.44 188/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.37.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 212 in the user submitted sequence), (cause frameshift) gtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtattttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13185 JY8QFUQ01AD5UE productive Homsap IGHV3-74*03 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + cctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13186 JY8QFUQ01A6B9M productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13187 JY8QFUQ01BB385 unproductive (see comment) Homsap IGHV3-72*01 F 894 89.24 199/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 10 X 8.10.X [1.17.38.11] CAVAAPPL#DGW out-of-frame + stop codons ctctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccgttatgacggctggggccagggaaccctggtcatcgtctcctcagcatcccgaccagcccgaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg 13188 JY8QFUQ01DO5KZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 849 88.79 190/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARVDFYGSSKYKGFDPW in-frame - ctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13189 JY8QFUQ01BYAQ8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt 91.82 202/220 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaAaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaCccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtgtgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13190 JY8QFUQ01AJO76 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcagtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13191 JY8QFUQ01CU0D5 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13192 JY8QFUQ01CRR42 productive Homsap IGHV3-7*01 F 952 94.37 201/213 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [X.17.38.11] CAKDGYYYYHSGMDVW in-frame - ggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13193 JY8QFUQ01AP0TZ productive Homsap IGHV3-9*01 F 958 93.52 202/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDAMGGAGDWAAFGIW in-frame + tctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctggtccagggcttcttccc 13194 JY8QFUQ01BEBP0 No results 13195 JY8QFUQ01BV9YG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccatcaagggccccatcggtcttccccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13196 JY8QFUQ01AB5DG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca 13197 JY8QFUQ01DRW2W unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRVGAPYYDFWSGYQTNWF#PW out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagcGtactggatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgaccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13198 JY8QFUQ01AITV3 productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1039 96.0 216/225 nt 95.56 215/225 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 10 9 8.10.9 [2.17.38.11] CTRGGYSYAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); acttctggattcacctttggtgattatgctatgagttggttccgccaggctccagggaaggGggctggagtgggtaggtttcattggaggcagagctcatggtggggcaacagaatacgccgcgtctgtgaaaggcagattcatcatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtactagagggggatacagttatgcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13199 JY8QFUQ01ANXRG productive Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13200 JY8QFUQ01DOYIV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaacGaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13201 JY8QFUQ01AEKPA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 841 87.5 189/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13202 JY8QFUQ01BPUYM unknown (see comment) Homsap IGHV3-11*01 F (see comment) 633 77.1 165/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BPUYM ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13203 JY8QFUQ01A3IWM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 979 95.77 204/213 nt 95.31 203/213 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 173 in the user submitted sequence), (cause frameshift) tggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13204 JY8QFUQ01DH3WS productive Homsap IGHV3-11*01 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [2.17.38.11] CVRRVWGYSYGSVSYYFDYW in-frame - gcctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacggccacgtattattgtgtgaggcgggtctggggatacagttatggttccgtttcgtattacttcgactactggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13205 JY8QFUQ01BU6WY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagttataGgcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13206 JY8QFUQ01COFUI No results 13207 JY8QFUQ01BUNIG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13208 JY8QFUQ01A2PDE productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13209 JY8QFUQ01B7HB0 No results 13210 JY8QFUQ01B62DJ unproductive (see comment) Homsap IGHV4-61*02 F 951 92.73 204/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + stop codons ctctggtggctccatcaggagtggtagttactactggagctagatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13211 JY8QFUQ01B4WCZ productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame - cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13212 JY8QFUQ01CF2KP productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + ttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13213 JY8QFUQ01AWDF7 No results 13214 JY8QFUQ01BY1KF unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame + stop codons ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13215 JY8QFUQ01C3HIA productive Homsap IGHV3-30*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + ctctggattcaacttcaggacctattctatgcactggctccgccaggctccaggcaagggactagagtgggtatcagttatttcatatgatggaactaagaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctacaaatggacagcctgagacctgaggacacggctgtgtattactgtgcgagagatgaactgccttgggatacaatagagtattactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 13216 JY8QFUQ01C8XR0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggccccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 13217 JY8QFUQ01BDT1C No results 13218 JY8QFUQ01DE4Y3 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13219 JY8QFUQ01BZ3OY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDYGNCGGGRCYSIPLDYW in-frame + cctctggatttacctttagccgctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcattattgatgttaattctttcacatactacgcagactctgttcggggccggttcaccgtgtccagagacgattccaagaacacggtatatctgcaaatgaacagtttgagacccgacgacacggccgtttattattgtgtgaaagattacggtaactgtggtggtggtcgctgctattcgattccccttgactactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13220 JY8QFUQ01B3EPF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13221 JY8QFUQ01A907V No results 13222 JY8QFUQ01CSN3B unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ6*01 F (see comment) 94 60.32 38/63 nt 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFGRT (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggacgaacctggggccaggaacctggtcnccgtctcctcagcctccagccaaggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13223 JY8QFUQ01BWLOU productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13224 JY8QFUQ01CAMSA unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 977 94.5 206/218 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13225 JY8QFUQ01CQ2XD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARVDFYGSSKYKGFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gtctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcCttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataaggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13226 JY8QFUQ01C3IXU No results 13227 JY8QFUQ01AHEF7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacctctatgtcatgcactggttccgGccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaAagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtcggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca 13228 JY8QFUQ01CA2ZN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - tctggattcacctttagcatctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcgactattagtggtagtggaaatagtacataccatgcagactccatgaagggccggttcaccctctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13229 JY8QFUQ01A73LL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKGMGTVVVTNTPLYPFDIW in-frame + cctctggattcaactttgacagcagtgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagccattagtggtcgtgctttcggcacagactacgcagcctctgtgaagggccggttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgcgagtcgaggactcggccatatattactgtgcgaaaggcatggggacagtggtggtcactaatactccgttgtatccttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcatctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13230 JY8QFUQ01A7O0L unknown (see comment) Homsap IGHV3-11*01 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ggctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13231 JY8QFUQ01AKSKE productive (see comment) Homsap IGHV2-5*02 F 1147 97.12 236/243 nt 96.3 234/243 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.16.38.11] CAHRRIRFGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) acccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggcCtggatccgtcagcccccaggaaagccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13232 JY8QFUQ01BALM2 No results 13233 JY8QFUQ01DQ8UA No results 13234 JY8QFUQ01DRKGA No results 13235 JY8QFUQ01BELWX unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 738 82.03 178/217 nt Homsap IGHJ1*01 F (see comment) 28 72.73 8/11 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13236 JY8QFUQ01CQ5DQ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13237 JY8QFUQ01DAH2M productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaagggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13238 JY8QFUQ01DJ4KO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13239 JY8QFUQ01CEF1U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13240 JY8QFUQ01B8DED productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDPW in-frame + tctctggtgactccatcagtagtaactactggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13241 JY8QFUQ01AOZQ7 No results 13242 JY8QFUQ01DAF4D productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 7 7 10 7.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaggagtattattggagttggatccggcagcccccaggaaagggactggagtggattggttataCttaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13243 JY8QFUQ01CMWHN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaa 13244 JY8QFUQ01DT743 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13245 JY8QFUQ01BZLJJ productive Homsap IGHV1-18*01 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [0.17.38.11] CVREESIVVVTGRRGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccatgtattattgtgttagagaagagtcaattgtggtggtgaccgggcggcggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13246 JY8QFUQ01B8OYO unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDLFQVSTTYFDY## out-of-frame + tctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggcccggggaaccctggtcaccgtctcctcagcctccaccaagggccccattcggtcttccccctggcaccctctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13247 JY8QFUQ01BE1GG productive (see comment) Homsap IGHV4-61*02 F (see comment) 654 77.73 171/220 nt 77.27 170/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.16.38.11] CARERDRSIGGAAELDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) tctccaatgtacccatcagtcgtggaggttactactggaattggatccggcaggccgccgggaagggctggagtggcttggacgtgttgacagtaatggattcgtcaggtacaattcttccctcaaaagtcgcctttctatgtcactagacacgtccaagaatcagatctccctgatattgaggtctgtgatcgccgcagacacggccgtatatttctgtgcgagggagcgtgataggtcgatcggtggagcggcagaacttgactcctggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13248 JY8QFUQ01AR58C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13249 JY8QFUQ01B5XE3 productive (see comment) Homsap IGHV4-61*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 9 7 15 9.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctctggtgcctccataataggggtaattattactggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13250 JY8QFUQ01ANW3Z No results 13251 JY8QFUQ01AZLYZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccttgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 13252 JY8QFUQ01BSPM8 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDNLR*LLG in-frame + stop codons ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataatttacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13253 JY8QFUQ01A8BQT productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARAKRFWGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagcaaaaaggttctggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 13254 JY8QFUQ01DQMVS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13255 JY8QFUQ01COT7A productive Homsap IGHV3-7*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtctgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13256 JY8QFUQ01ATOXX productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13257 JY8QFUQ01C8QQV unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13258 JY8QFUQ01BNB5K productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13259 JY8QFUQ01CC01V productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13260 JY8QFUQ01CSCCB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13261 JY8QFUQ01CYKSC productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13262 JY8QFUQ01COKNO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13263 JY8QFUQ01B8KX2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacactgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13264 JY8QFUQ01CH4A6 No results 13265 JY8QFUQ01DNGQ9 No results 13266 JY8QFUQ01B3J3Q No results 13267 JY8QFUQ01AW8ZH unproductive Homsap IGHV3-30*04 F, or Homsap IGHV3-30*10 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30-3*03 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARDLASFCGGDCPIDY## out-of-frame + in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); cctctggatTtccccttcagcaattacgctatgcactgggtccgccaggctccgggcaaggggctggagtgggtggcacttatttcgtatgatgggactaataaatactacatagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacagtgtatctgcaaatgaatagcctgagacgtgaggacacggctgtgtatttctgtgcgagagatctggcatcattttgtggtggtgactgccccattgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 13268 JY8QFUQ01DCAKQ productive Homsap IGHV3-9*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame - tctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13269 JY8QFUQ01BCEIV productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13270 JY8QFUQ01ADCOG unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaac 13271 JY8QFUQ01CNT10 No results 13272 JY8QFUQ01C2CN9 No results 13273 JY8QFUQ01B4PG0 productive Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F 389 90.53 86/95 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 X X 11 X.X.11 [X.X.31.11] CARSGSGSHLDYW in-frame - tctctggattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13274 JY8QFUQ01CAV9Y productive (see comment) Homsap IGHV3-72*01 F 1073 98.64 218/221 nt 98.19 217/221 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.16.38.11] CLRPPRYDPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) tctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13275 JY8QFUQ01CNGY0 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacacgcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13276 JY8QFUQ01DIC8Q No results 13277 JY8QFUQ01CLO2L productive Homsap IGHV1-8*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CAREGLLGSLGSW in-frame - aggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13278 JY8QFUQ01A8ZQP unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGFLFFGELRRLRNGRL# out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaGggggctagattgggtggcatttatatcatatgatggaagtaatGaggttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatggatttctattcttcggggaattacggaggcttcggaatggacgtctgggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13279 JY8QFUQ01AVC1T unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 368 64.39 132/205 nt 63.9 131/205 nt 8 7 X 8.7.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (64,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13280 JY8QFUQ01CR5H7 unknown (see comment) Homsap IGHV3-23*05 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13281 JY8QFUQ01B94JE unproductive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13282 JY8QFUQ01AOYC9 unproductive Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGGLRWGLLEFDPG#W out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 111 to 122 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggctccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13283 JY8QFUQ01AJRBP No results 13284 JY8QFUQ01CVFLT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13285 JY8QFUQ01BVCWL productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13286 JY8QFUQ01C76FG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13287 JY8QFUQ01B5LCE productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARLRDYEYSYGHPRAFDYW in-frame + ctctggattcacctttaataactactggatgagttgggtccgccaggctccagggaaggggctggactacatggccaatataaaggcagatggaagtgcgaagaattatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatttgcaactgaacagcctgagagtcgaggacacggctgtatatttctgtgcgagattgagggattatgaatacagctatggtcacccaagggcctttgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13288 JY8QFUQ01CY2HZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1035 97.7 212/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13289 JY8QFUQ01CBNOH productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13290 JY8QFUQ01CNKWE unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARLTPLTMVPGNSLL#YHSMDVW out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'CACAACCCCTCCCTCCTG' (18 nucleotides at position 123 to 140 in the user submitted sequence), (do not cause frameshift); tctctggtggctccatgactggttactactggagttggatccggcggcccccaggtaagggactggagtggattggctatatctactacaccgggtacaacaactacaacccctccctcatcCACAACCCCTCCCTCCTGagtcgactcaccatatcagtcgacacgtccaagaaccagttctctctgacgctgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagattgacacccctgactatggttccggggaactcactactattaccacagtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13291 JY8QFUQ01COFUU productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcgggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13292 JY8QFUQ01CIBI1 No results 13293 JY8QFUQ01AZAQN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 13294 JY8QFUQ01BV7SZ unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 96.65 202/209 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 6 8 X 6.8.X [X.17.38.11] CARQIDYGDFSRHGLDV## out-of-frame + acaactttaccggctactggatcggctgggtgcgccagcggcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccatccttccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaaatagactacggtgacttctctaggcacggtttggacgtctggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13295 JY8QFUQ01DRW1N No results 13296 JY8QFUQ01DW5HG unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGEWEMLDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatTttttgtgcaagagacggggagtgggagatgcttgaccactgggggccagggagccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 13297 JY8QFUQ01A7WQR unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 878 89.45 195/218 nt 88.07 192/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.17.38.11] CAREPPETIVVVVTVL#GAFDIW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 140 to 140 in the user submitted sequence), (cause frameshift); ctgtctctggtggctcCcatgaggaattattacCtggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccCttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagaaccccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13298 JY8QFUQ01C5DFE productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13299 JY8QFUQ01CBFFI productive Homsap IGHV2-5*02 F 1170 97.95 239/244 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.17.38.11] CAHRRIRFGFDYW in-frame + gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13300 JY8QFUQ01BFE2F productive (see comment) Homsap IGHV3-30*01 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARDSVPRASEAAYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); gcctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttaCtttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13301 JY8QFUQ01DBM06 productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 13302 JY8QFUQ01A4F8J unproductive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13303 JY8QFUQ01B05FW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 13304 JY8QFUQ01CQHZF No results 13305 JY8QFUQ01AMSW8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13306 JY8QFUQ01BPEAY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13307 JY8QFUQ01A239T productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 807 85.45 188/220 nt 84.55 186/220 nt Homsap IGHJ6*02 F 187 79.66 47/59 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARRDSDFRMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); ggtgtctggatatgactttagcagattttGggatcgcctgggtgcgccagatgcccgggaaaaggctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctacttTtttagcagtctgagggcctcggacaccgccatgtatttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggaccacggtcaccgtgtctccaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 13308 JY8QFUQ01BNPKU productive (see comment) Homsap IGHV3-9*01 F 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDRGSSSKYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in CDR3-IMGT at codon 105 of V-REGION: 'T' (1 nucleotides at position 220 to 220 in the user submitted sequence), (cause frameshift); ctctggattcaactttggtgattacgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttGggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgTcaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13309 JY8QFUQ01APGJK unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13310 JY8QFUQ01AIUAX productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13311 JY8QFUQ01BY77H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13312 JY8QFUQ01ASBW4 productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 13313 JY8QFUQ01DKFWU productive (see comment) Homsap IGHV3-33*05 F (see comment) 757 83.11 182/219 nt 82.65 181/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13314 JY8QFUQ01DE4DF productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVYNSRTNYFDLW in-frame + gtctggatttagcttcactaatcatggcatgcactgggtccgccaggctccaggcaaggggctggaatgggtggcacttattgtcgacgatggaagtaatggatattatgcagaccccgtgaggggccggttcaccatctccagagacaatcccaaaaacacactttatctgcaaatggacagcctgagagccgaggacacggctgtctactattgtgcgagagatgtctacaattcccgaactaattactttgacctatggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13315 JY8QFUQ01BM631 productive Homsap IGHV3-11*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDRGKSGSYGLDHW in-frame + cctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatcgggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttccgctgagcctcgacagcaccccccaagcatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 13316 JY8QFUQ01CM33P productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 979 93.69 208/222 nt 93.24 207/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [2.17.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcatcagagacagtgcctactggggctggatccgccagcccccagggaaggGggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13317 JY8QFUQ01DFMQ1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARWRSRSYDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattacaagtggtggtagcacatactacgcaaactccgtgaagggccggttcaccgtctccagagacagttccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagatggcgtagtcggagctacgactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13318 JY8QFUQ01ASBGR productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13319 JY8QFUQ01AR4XZ productive (see comment) Homsap IGHV3-48*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); cctctggatTtcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13320 JY8QFUQ01B9ETA unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 473 68.35 149/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.37.X] null + stop codons no junction found Low V-REGION identity (68,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13321 JY8QFUQ01A6CLA No results 13322 JY8QFUQ01A30KO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13323 JY8QFUQ01A1SIW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13324 JY8QFUQ01CDMFR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1000 95.43 209/219 nt 94.52 207/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtcgttatagcatgaactggGgtccgccaggctccagggaagggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13325 JY8QFUQ01DF7T4 No results 13326 JY8QFUQ01BDGYS unproductive Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.73 189/213 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDPYCSSTNCYPY## out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13327 JY8QFUQ01CU5JV productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [0.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13328 JY8QFUQ01AJY27 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.37.11] CVRSEYSSSNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcgggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13329 JY8QFUQ01CHKDD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13330 JY8QFUQ01A20T6 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 889 91.08 194/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 6 9 8.6.9 [1.17.38.11] CAKEEVPNDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 13331 JY8QFUQ01ANT8E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame + cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13332 JY8QFUQ01A17TV productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.02 196/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagTttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13333 JY8QFUQ01CPYJ0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttccccgctgagccctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13334 JY8QFUQ01DA34V productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcg 13335 JY8QFUQ01AZRBH No results 13336 JY8QFUQ01AMCLQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13337 JY8QFUQ01BRY5N No results 13338 JY8QFUQ01BRRF8 productive (see comment) Homsap IGHV4-61*02 F 834 86.43 191/221 nt 85.52 189/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtacCtggttattactactGggagctggatccggcagtccnccggggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13339 JY8QFUQ01BF3SF unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-13*01 F 3 X X X X.X.X [X.X.28.11] CVKDRKGSNWYYFEN# out-of-frame + Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactgggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13340 JY8QFUQ01BJRW3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEAVSNMDDAFDIW in-frame + ctctggattcagcttcagtggttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcatacattagtaggaggagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgggaggcgaggacacggctgtgtatttctgtgcgagagacaccctagaggcagtgtctaatatggatgatgcttttgatatctggggccaagggacaatggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13341 JY8QFUQ01C5XHC unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGH# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13342 JY8QFUQ01AYAME productive Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F 944 93.49 201/215 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccaggccagatgggaacgtggtcatcgcctgcctggtcccaggggcttcttccccca 13343 JY8QFUQ01AUIPX No results 13344 JY8QFUQ01C44NL productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 925 92.96 198/213 nt 92.02 196/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.37.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'AC' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 173 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcaataggaaACtgacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13345 JY8QFUQ01AS6HF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 743 82.57 180/218 nt 81.19 177/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'T' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaaGgggctggagtgggtctccagtatTtagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacGctgttttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13346 JY8QFUQ01DK32V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13347 JY8QFUQ01CFEJB unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt 90.32 196/217 nt 8 8 X 8.8.X [1.17.37.X] null + No rearrangement found in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcgggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgaccctggggccaggggaccctggtaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 13348 JY8QFUQ01C08YX productive (see comment) Homsap IGHV4-59*03 F 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.37.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) tctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13349 JY8QFUQ01C0V8V productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ6*02 F 175 75.81 47/62 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [2.16.38.11] CARAVGQRGYDGTDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcatgttcagcagttattggatgagctgggtccgccaggatccagggaagggctggagtgggtggccaatataaacgaagaaggaagtgagaaatattatgtggactctgggaagggccgattcaggatctccagagacaacgccaagaattccgtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagcagtggggcagcgaggctacgacggtacagacctctggggccaagggaccacggtcatcgtctccacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13350 JY8QFUQ01CYZEY unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNG#DFW out-of-frame + tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacgggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13351 JY8QFUQ01BFYY9 productive Homsap IGHV3-48*02 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [2.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame - ggctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13352 JY8QFUQ01B0OA1 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + cctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13353 JY8QFUQ01AYS47 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13354 JY8QFUQ01B6NYK productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13355 JY8QFUQ01BSIRY productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13356 JY8QFUQ01B0FUB productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctggggcacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13357 JY8QFUQ01A2SLU unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1029 95.96 214/223 nt 95.07 212/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-24*01 ORF 1 10 9 X 10.9.X [0.17.37.11] CASEQR*PPR#FDYW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift) tccgggacagtgtctctagcaacagtgctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtgatataatgattatgcaatatctatgaagagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaactgaatctgtgactcccgaggacacggctgtgtcttattgtgcaagtgagcagagatgaccacctagaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13358 JY8QFUQ01BL0VW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13359 JY8QFUQ01A8YWU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 7 17 8.7.17 [2.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) gcgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtggtcataatgcagcctacgcagatttcgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13360 JY8QFUQ01A9SRR unproductive Homsap IGHV4-61*02 F (see comment) 879 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] LXRDKGIVVDPG#DYW out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtattttttggngcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13361 JY8QFUQ01DV1Q5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 13362 JY8QFUQ01CEJL7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13363 JY8QFUQ01BUU3D unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKLADTGEWSNRIFI#W out-of-frame - tctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13364 JY8QFUQ01DAGOQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13365 JY8QFUQ01AX6NH productive (see comment) Homsap IGHV3-9*02 F (see comment) 665 79.07 170/215 nt 78.14 168/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 7 7 15 7.7.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 59 of V-REGION: 2 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) cctctggattcaacccgaaaactttgccatgcactgggtccgacaagttccagggaagggcctgaagtgggtctcaggtataattggaatggacgaaaacaggatatgcggagtctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13366 JY8QFUQ01BCW6H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13367 JY8QFUQ01BP55P productive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13368 JY8QFUQ01BOHMT No results 13369 JY8QFUQ01DAUMA unproductive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASDLGGQKSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 13370 JY8QFUQ01DF8OD productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.08 215/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgaGttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag 13371 JY8QFUQ01BVD6B productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 732 82.71 177/214 nt 82.24 176/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.16.38.11] CARDWGGSFDRYYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13372 JY8QFUQ01B1I2X No results 13373 JY8QFUQ01CZDE0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDPQQILAEVNWFDPW in-frame + cctctggattcacctttcgcagctacgccatgagttgggtccgccaggctccaggaagggggctggagtgggtctcctcaatcagtggcagtggtgataaaacaaaatatgcagactccgtgaagggccgattcaccatctccagagacaatgcgaggaacactttttatctgcatatgaacagcctcagagccgcggacacgggcgtctactattgtgcgaaagatcctcagcagatactggcagaagtaaactggttcgacccctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13374 JY8QFUQ01DGXWV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGHLLD#DYW out-of-frame - in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgGggtccgccaggctccagggaaggGggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtngaggacacggccgtttattactgtgcgagattcggccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13375 JY8QFUQ01A8G7W No results 13376 JY8QFUQ01B2Y30 unknown (see comment) Homsap IGHV1-2*01 F, or Homsap IGHV1-2*02 F or Homsap IGHV1-2*04 F or Homsap IGHV1-2*05 F 142 82.93 34/41 nt 8 X X 8.X.X [0.5.X.X] null + No rearrangement found tggatacacattcaccggccacttcgtccactggctgcgac 13377 JY8QFUQ01CD2NF productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 875 90.57 192/212 nt 90.09 191/212 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 6 15 8.6.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattctgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 13378 JY8QFUQ01DSGPB productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 921 90.58 202/223 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame + ctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 13379 JY8QFUQ01B4PTS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 88.43 191/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'ACT' (3 nucleotides at position 82 to 84 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 145 to 145 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); tctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattACTaatggtggtggtggtgtcgtactctacgcagactccgtgaagGggccgattcaccatctcCcagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttaGtttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13380 JY8QFUQ01BI30M No results 13381 JY8QFUQ01B0L5R productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccaggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13382 JY8QFUQ01DJ2CJ No results 13383 JY8QFUQ01BMUVB No results 13384 JY8QFUQ01DTIOK No results 13385 JY8QFUQ01BOGQI productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13386 JY8QFUQ01CK7Z9 productive Homsap IGHV3-11*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARLASSSGWYFDYW in-frame + ctctgaattcctcttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtaatagtggtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagattagcaagtagcagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 13387 JY8QFUQ01C4L2P No results 13388 JY8QFUQ01ALBC2 No results 13389 JY8QFUQ01DGY0R productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 84.23 187/222 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tcctttggtggctccatcagcCaataataattacttcctgggctggatccgccaGgcccccagggaaggggctggagtggattCggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcctgcctggtccagggcttcttccccca 13390 JY8QFUQ01C58JQ productive Homsap IGHV3-33*05 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13391 JY8QFUQ01ASO1O productive Homsap IGHV3-66*02 F 926 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CSTPTYCRGGSCSQIFDYW in-frame + cctctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagatttttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13392 JY8QFUQ01A5MH8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 980 95.35 205/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.16.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctggattcacctacagcagctatgccatgagctggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13393 JY8QFUQ01B8KSE productive Homsap IGHV3-30*10 F (see comment) 734 82.11 179/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 13394 JY8QFUQ01AGZXJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13395 JY8QFUQ01CPHOZ productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13396 JY8QFUQ01DI527 unknown (see comment) Homsap IGHV1-2*02 F 551 91.54 119/130 nt 8 8 X 8.8.X [X.17.10.X] null + No rearrangement found ggatacaccttcaccggcacctatatacactgggtgcgacaggcccctggacaagggcttgagtgggtgggattaatcaaccctagcagtggtggcacagagtctgcacagaagcttcagggcagggtca 13397 JY8QFUQ01CL2UN productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13398 JY8QFUQ01BAQO7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGV*QWL##DFDCW out-of-frame + stop codons cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13399 JY8QFUQ01B1Z10 No results 13400 JY8QFUQ01DS4FP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13401 JY8QFUQ01CM7R2 No results 13402 JY8QFUQ01CWYLL productive Homsap IGHV4-61*02 F 960 93.18 205/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + ctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13403 JY8QFUQ01BUVHG productive (see comment) Homsap IGHV3-7*01 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); agcctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13404 JY8QFUQ01DR2MY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-11*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARHLTPEDAFDIW in-frame + ctctggattcacctttgacaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtgttagtggtcctggtggtaacacataccacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacatgctgtttctgcaaatgaacagtctgagggtcgaggacacggccgtttattactgtgcgagacacctgactccagaggatgcttttgatatttggggccaagggacaatggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13405 JY8QFUQ01BVAV2 unproductive (see comment) Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-16*01 F 2 8 7 X 8.7.X [1.17.38.11] CARQTAPFGVL*GL# out-of-frame + stop codons ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttggggtactttgaggactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 13406 JY8QFUQ01CEFA0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13407 JY8QFUQ01CBDGL unproductive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13408 JY8QFUQ01AFBW7 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 906 90.0 198/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found agcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13409 JY8QFUQ01DVAOU productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaTggggctggantgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13410 JY8QFUQ01DO65C No results 13411 JY8QFUQ01BDP3S productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13412 JY8QFUQ01COSJG productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13413 JY8QFUQ01AJVUU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 270 92.19 59/64 nt Homsap IGHJ4*02 F 199 89.58 43/48 nt Homsap IGHD3-22*01 F 3 X X 19 X.X.19 [X.X.21.11] CAKDVSTRITMRVVVPXLDYW in-frame - taagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccancccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 13414 JY8QFUQ01CG89R productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 749 82.27 181/220 nt 81.82 180/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); tctcgggtggttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctAggagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13415 JY8QFUQ01CHPQV No results 13416 JY8QFUQ01AOYZF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcagtactggatgtactgggtccgccaagntccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13417 JY8QFUQ01CHHBI productive Homsap IGHV3-11*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaaaaactcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13418 JY8QFUQ01BNH8C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 922 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacnccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13419 JY8QFUQ01B0MOL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKPPPVDIVVTT#EFW out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); tctctggattcacctttaacaactatgccctgagttggttccgccaggctccagggaggggactggagtgggtctcagccgttagtggtagtggtgattatacatattacgcagactccgtgAaagggccggttcaccatttccagagacaattccaagaacacactgtggctgcaaatgaacagactgagagccgaagacacggccgtatattactgtgcgaagcctccccccgtggatatagtggtgacgacattgagttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13420 JY8QFUQ01B0MKR No results 13421 JY8QFUQ01BJ8BC productive (see comment) Homsap IGHV3-11*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 95 to 97 in the user submitted sequence), (do not cause frameshift); ttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 13422 JY8QFUQ01CB01H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag 13423 JY8QFUQ01BV9NQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift); aggcctctggattcaccCTttgggttattatggcatggactgggtccgccaagctccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13424 JY8QFUQ01CGG9A productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13425 JY8QFUQ01B7JOI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 13426 JY8QFUQ01AEO6U productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13427 JY8QFUQ01DODF2 unproductive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt 99.08 216/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CASIFGVVPPG##YYYGMDVW out-of-frame + in FR3-IMGT at codon 94 of V-REGION: 'C' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcCctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttccccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttgccccgaaccggtgacggtgtcgtggaaactca 13428 JY8QFUQ01CSCY0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatcccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13429 JY8QFUQ01BLSTS No results 13430 JY8QFUQ01C5A15 productive Homsap IGHV1-3*01 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CVRGRSPPGDWFDPW in-frame + tggatacaccttcactaattatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctgtcaccgtctccgtcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13431 JY8QFUQ01CKL3B No results 13432 JY8QFUQ01BM80W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 912 91.59 196/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [0.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + tggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13433 JY8QFUQ01B80FV productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 959 93.58 204/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame - cctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13434 JY8QFUQ01CA99E unproductive (see comment) Homsap IGHV3-11*04 F (see comment) 450 67.28 146/217 nt Homsap IGHJ2*01 F 31 64.71 11/17 nt Homsap IGHD7-27*01 F 3 8 8 2 8.8.2 [1.17.38.5] NR*R in-frame + stop codons Low V-REGION identity (67,28% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13435 JY8QFUQ01C8YCZ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 110 100.0 22/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttcagtga 13436 JY8QFUQ01A19DA unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 605 78.87 153/194 nt 78.35 152/194 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-22*01 F 2 8 1 X 8.1.X [1.16.38.11] ESVAPLLLMIR#PG out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01A19DA ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (78,87% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 24 nucleotides (from position 78 in the user submitted sequence), (do not cause frameshift) cctctggactctccttcagtgggtaaaatatgaactgggtccgccaggctccaggggagggactggagtgggtctccaaatattacacagactcactgaggggccgattcaccatctccagagacagcgccaagaactcactccttctgcaaatgaacaggctgagagtcgaagtgtgcgaaaaaacgagagaaagtgtggcacccctgttactaatgattcgacccctggggccggggaaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctgacgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13437 JY8QFUQ01AV35P No results 13438 JY8QFUQ01CO4OD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgGacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13439 JY8QFUQ01DEZVI productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaagggactacttccccgaaccggctgacggtgtcgtggaactca 13440 JY8QFUQ01AUKEV No results 13441 JY8QFUQ01BV2F7 productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 929 91.4 202/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccc 13442 JY8QFUQ01ANXF5 No results 13443 JY8QFUQ01C89O8 productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13444 JY8QFUQ01AIVDQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggccctcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13445 JY8QFUQ01ADNGT productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame - gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13446 JY8QFUQ01AZDHR unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 819 97.66 167/171 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc 13447 JY8QFUQ01CJOWG productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13448 JY8QFUQ01CCQXQ No results 13449 JY8QFUQ01AHXYO productive (see comment) Homsap IGHV3-7*01 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRDLTADFYVSGSYRSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaggagttattggatgaattgggtccgccaggctccagggaaGggggctggagtgggtggccaccataaAagcaagatggaagtgagaaatattatgtagactctgtgaagggccgattcaccatctccagagacaacgccaatgattcactgtatctgcaaatgaacagccttagaaccgaggacacggctgtgtattactgtgtgagagatttaacagcggatttctatgtttcggggagttatcggtcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 13450 JY8QFUQ01BDV4O productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13451 JY8QFUQ01DJ0K8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13452 JY8QFUQ01AJ3PL No results 13453 JY8QFUQ01BTMQU No results 13454 JY8QFUQ01CI2OQ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13455 JY8QFUQ01AEVWH productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame + ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13456 JY8QFUQ01BE1BL productive Homsap IGHV3-13*01 F, or Homsap IGHV3-13*02 F (see comment) 746 83.26 179/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*02 F 2 8 7 18 8.7.18 [1.17.38.11] CARGRRDYYDRSAYPHLDSW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gctctggattcatcttcactaactccgacatgcactgggtccgccaaactccaggagggagtctggagtgggtctcaggcattggaactgctgctgacacattctatgcagactctgtgaggggccgcttcaccatctccagagacaatcccaaggactcgatgtaccttcagatgaacagcctgagagccgaagacacgggcatatatttttgtgcaagaggacgtagagattactatgataggagtgcttatccccacctcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13457 JY8QFUQ01ASSOO unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGTPV*QRS#DAFDVW out-of-frame + stop codons Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggaccccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13458 JY8QFUQ01BJOCP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13459 JY8QFUQ01ATTL9 productive (see comment) Homsap IGHV3-30*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 7 8 16 7.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaatatttttctatgcactgggtccgccaggctccaggcaagggactagagtgggtgtcacttgtttcatatgatggatctaagaaaaagtacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccc 13460 JY8QFUQ01A2YPP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 915 90.91 200/220 nt 90.0 198/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [2.17.38.11] CATSRGSANWYPFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); agcctctggattGcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaAatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13461 JY8QFUQ01ANQTV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame - ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca 13462 JY8QFUQ01A23UZ productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13463 JY8QFUQ01C0WA2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13464 JY8QFUQ01DJQF1 No results 13465 JY8QFUQ01BPYSL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13466 JY8QFUQ01AFO27 unproductive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFYSTGY## out-of-frame - cctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13467 JY8QFUQ01BRI34 unproductive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFS#YYSGLDVW out-of-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgaccctttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13468 JY8QFUQ01CEEMM productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 585 92.65 126/136 nt 91.91 125/136 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 X 15 8.X.15 [0.3.34.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 78 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacaccttcagcaactactatagacactggaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13469 JY8QFUQ01DDGWX productive (see comment) Homsap IGHV3-9*01 F 904 91.2 197/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'CG' (2 nucleotides at position 138 to 139 in the user submitted sequence), (cause frameshift); tctggattcaccGtttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaagGggccgattcaccCGtctcccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13470 JY8QFUQ01CCBKP No results 13471 JY8QFUQ01AGO9G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13472 JY8QFUQ01DKWW9 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 934 91.44 203/222 nt 90.99 202/222 nt Homsap IGHJ6*01 F (see comment) 125 76.74 33/43 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [1.17.37.11] CTTESAY# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccagggaaggggctggagtggcttggccgtattaaaaggaaagttgatggtgagacaacagactacgctgcatccgtgaagggcagattcaccatctggagagatgactcaaaaacactctatatctgcaaatgaacagcctggaacccgaggacacagccgtatattattgtaccactgaatctgcctattggggccagggaacctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgcctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13473 JY8QFUQ01BDHUE productive Homsap IGHV3-7*03 F 806 85.78 187/218 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13474 JY8QFUQ01CLKWA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13475 JY8QFUQ01BJQ6B productive Homsap IGHV1-2*02 F 790 85.51 183/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggngcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgcctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13476 JY8QFUQ01CEHBJ productive Homsap IGHV1-2*02 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*01 F 3 8 8 19 8.8.19 [0.17.38.11] CARDEANIEVVMTSNYYFDYW in-frame + tggatacaccttcaccggccactatctacactgggtgcgacaggcccctggacaaggacttgagtggatgggatgggtaaacatcaagagtggtgacacaaattatccacagaagtttcacggcaggatcaccatgaccagggacacgtccatcaacacagccttcttagaagtgaccagcctgagatctgacgacacggccgtttattactgtgcgagagacgaggccaatattgaagtagtaatgacctctaattattattttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 13477 JY8QFUQ01CG5NM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [0.17.38.11] CAKDLVVTQYWPQGIHGHW in-frame - ctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactcagtattggccccagggaatccatggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13478 JY8QFUQ01CL755 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDEIPWDTIEYY#FDYW out-of-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtgtattactgtgccagagatgagatcccttgggatacaatagagtactaccttttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagacctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 13479 JY8QFUQ01CGW3W unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null - No rearrangement found tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgaacccctgggggccagggaaaccctgggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 13480 JY8QFUQ01CMB6M productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13481 JY8QFUQ01CUOC4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 13482 JY8QFUQ01B95BW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13483 JY8QFUQ01CZZ6E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgGggagtggtnttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13484 JY8QFUQ01DTRRU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13485 JY8QFUQ01BFUON unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CARLGATR##DYW out-of-frame + stop codons tggatacagctttaccaattactggatcggctgggtgcgccaggtgcccggaaaaggcctggagtggatggggagcatctatcctcgtgactctgacaccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttggggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13486 JY8QFUQ01AVQS1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 799 86.38 184/213 nt 85.92 183/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.37.11] CATLRGGTFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaaccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13487 JY8QFUQ01AG5SF No results 13488 JY8QFUQ01CDJWO unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1070 97.77 219/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*02 F 3 8 10 X 8.10.X [1.17.38.11] CTTDGGPSRP#FDFW out-of-frame + stop codons cctctggattcaccttcagtaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgctggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaagaacacgctgtatttgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtaccacagatggggggccatctcgtcccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13489 JY8QFUQ01C4CZ9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13490 JY8QFUQ01DBM8Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13491 JY8QFUQ01CYIO3 No results 13492 JY8QFUQ01ACVYI No results 13493 JY8QFUQ01COR4B productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 921 90.58 202/223 nt 90.13 201/223 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-15*01 F 2 8 10 18 8.10.18 [1.17.38.11] CATHGVGSSWAHYYFGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); ctctggattcaccctcaaaaacgcctggacgagctgggtccgccagggtccagggaaggggctggagGtgggttggccgcattaagagcaaatctgaaggtggggcaatagactacgctgcacccgtgaagggcagatttaccatctcaagagatgattcagaagacacactgtttctgcaaatgaacagcctgagagccgaggacacagccgtgtattattgtgccacgcacggtgttggcagcagctgggcccactactacttcggtctggacgtctggggccaagggaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacaacacccccccaagtggtcgtcgcatgcctggtccagggcttcttccccca 13494 JY8QFUQ01A3ZP1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) ggcctctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13495 JY8QFUQ01BO268 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGHW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 13496 JY8QFUQ01CFT0C No results 13497 JY8QFUQ01DCWKM productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 13498 JY8QFUQ01CTU32 productive Homsap IGHV3-48*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13499 JY8QFUQ01CMTAN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13500 JY8QFUQ01B2JS1 productive (see comment) Homsap IGHV3-7*01 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.37.11] CGRDERGADLPNDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13501 JY8QFUQ01AVA0Q productive Homsap IGHV2-5*02 F 1134 96.31 235/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [9.17.38.11] CAHRGNYGDYVFDSW in-frame + gaccctcacgctgacctgcaccttctctggattctcacttagcactagtgggatgggtgtgggctggatccgtcagcccccaggaaaggccctggaatggcttacactcatttattgggatgatgataagcgctacagcccatctctgaagagcaggctcgccatcaccaaggacacctccaaaaatcaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattattgtgcacacagagggaattacggtgactatgtttttgactcctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13502 JY8QFUQ01BHUV1 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 764 84.19 181/215 nt 83.26 179/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARRPPYGGNRFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); tgtctggtgggtcctccaatggattttactgggactggatccgccagcccccagggaaggggctagaatggattggagaaatgaaccatgagggaagcagctcatacaccccgGtccctcagGgggtcgagtcaccatttcaggagacacgtccaagaaccagatctccttgaaaatcacctctgtgaccgccgcggacacggctgtatattattgtgcgagacgtcccccctatggtggtaatcgctttgactactggggccagggagtcctggtctccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 13503 JY8QFUQ01DQVYX productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13504 JY8QFUQ01AIH3K unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13505 JY8QFUQ01C61MV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13506 JY8QFUQ01CB3VX unproductive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGDLTGGSVLL*Q*WFK#YW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); tctagattcaGccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtAgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13507 JY8QFUQ01DPW2S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGLGAYYIYYFDSW in-frame + cctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggccggagtggctcgcaactatcagtggtagtggaagtaggtcattctacgcagactccctcaggggccgtttcaccatctccagagacaattccaagggcacggtgtacctggacatgaccaccctgggagccgacgactcggccgtgtattactgtgccagagatggagtccgtggccttggtgcttattatatctactattttgactcatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13508 JY8QFUQ01ALJ17 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVKGWYHIPDYW in-frame + ctctggatttacctttggcagctatgccatgagctgggtccgccaggctccaggcgaggggctcaagtgggtctcaactattggtggtagtgatggtcgcacatactacacagcctccgtgaagggcctgttcacctcctccagagacaattccaagaacacggtgtatctgcatatgaacggcctgagagtcgacgacacggccgtctattactgtgtaaaaggctggtaccacatcccagactactggggccagggaatcttggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13509 JY8QFUQ01B61YI productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13510 JY8QFUQ01BM39D unknown (see comment) Homsap IGHV3-72*01 F 102 53.03 70/132 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons tctctggattcaccttcagtgaccactacatggactgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 13511 JY8QFUQ01BWJ7V productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 872 89.77 193/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'TG' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccaTGgggaaggggGCccggtgtgggtctcacgtattaatgaagacggcagccCacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13512 JY8QFUQ01A82ZK unproductive Homsap IGHV4-39*03 F 880 88.69 196/221 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-10*01 F 3 10 7 X 10.7.X [2.17.38.11] CTREGT#YYYGMDVW out-of-frame - gtctctggcggctccatcagcaatactgattattactgggtctggatccgccagccccacgggaagggactggagtggattgggagtatcgatttcagtgggagcaccaactacaacccgtccctcaagagtcgagtctccatatccatagacacgtccgagaaccgattctccctgaggttgaattctgtgaccgccgcagacacggccgtctattattgtacgagagaggggaccctactactacggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13513 JY8QFUQ01C3410 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 874 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] LXETRG**WTLE#DYW out-of-frame + stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtattttttgngcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13514 JY8QFUQ01AYTNW productive (see comment) Homsap IGHV4-4*07 F 935 93.02 200/215 nt 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [2.16.38.11] CARGKDYYDSTGSLEDGLDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'AC' (2 nucleotides at position 14 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtggctACccctcagtacttactactggaactgggtccggcagcccgccggaagggactggagtggattgggcgtaaatatcccagtggggacaccaactataatccctAccctcaaaagtcgagtcaccatgtcactagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagggaaggattactatgatagtactggttccctcgaggatggtcttgatatctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13515 JY8QFUQ01DT8QJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13516 JY8QFUQ01CMSBH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13517 JY8QFUQ01DSCTQ productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13518 JY8QFUQ01DOLGG unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttAgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13519 JY8QFUQ01AHMZ7 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 404 65.42 140/214 nt 10 9 X 10.9.X [1.17.33.X] null + No rearrangement found Low V-REGION identity (65,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccgggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13520 JY8QFUQ01BNVKG productive (see comment) Homsap IGHV4-34*03 F (see comment) 760 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [2.17.38.11] CTRGRLDAWEVSDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gtcgacgatgggtcctgtagagagtgcttctggagttggatccgccagtccccagggaagggtctggagtggattAggggacgtcaattatagacgaggcgtcgactacaacccgtccctcaagagtcgagtgaccatatcattggacacgtccaacaaacaagtctccctgagtctgagttctgtcaccgccgcggacacggccatgtattattgtacgcgagggcgattagacgcgtgggaagtatcggaccactggggccagggaaccgtggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13521 JY8QFUQ01B889O productive Homsap IGHV1-3*01 F 831 87.85 188/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagagcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13522 JY8QFUQ01CZ6OP productive Homsap IGHV3-64*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVTCGDYSYEYW in-frame - ctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13523 JY8QFUQ01DLRZ7 productive Homsap IGHV3-7*03 F 846 88.02 191/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13524 JY8QFUQ01AXKCQ productive (see comment) Homsap IGHV3-11*01 F (see comment) 738 82.49 179/217 nt 82.03 178/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARGYSQKGVFDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) cctctggattcagtttcaaggaccactacatgagctggttccgccaggctccagggaagggactggagtgggttgcatacatcgatgccggtggggtactgactactacgcagactctgtggagggccgattcgtcgtcgccagggaaaatgacaagaatttattgcttctgcaaatgcacagcctgacagtcgaagacacggccgtatattactgtgcgagagggtacagtcaaaaaggggtttttgaccactggggccagggaatcctggtcaccgtttccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13525 JY8QFUQ01CLOBT productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.37.11] CARKRVPGGTFYGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagatccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 13526 JY8QFUQ01DCUR6 unproductive (see comment) Homsap IGHV4-39*02 F 839 86.88 192/221 nt 86.43 191/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHVVFGQ*IQCLASY##DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctGggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggtttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatcccctgaccagccccaaggtcttgcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 13527 JY8QFUQ01B77EG unproductive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CAREGAWLHLQEV#FDYW out-of-frame + stop codons in CDR2-IMGT at codon 59 of V-REGION: 'ATT' (3 nucleotides at position 96 to 98 in the user submitted sequence), (do not cause frameshift); tctctgacgactccatcagcagtggcacttactactggagttggatccggcagcccgccgggaaggctccggagtggattggccgcttctatactATTactgggcgcaccaactacaatccctccctcgagagtcgagtcaccataacaagggacgtgtccaagaatcagttctccctgagactgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagggggcatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 13528 JY8QFUQ01ALWQH productive (see comment) Homsap IGHV3-64*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatgggggAtaacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 13529 JY8QFUQ01CQLZA unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagcccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 13530 JY8QFUQ01BCDCV No results 13531 JY8QFUQ01C92CT productive Homsap IGHV3-21*04 F 869 88.99 194/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctctggatttaccttcagtctctatagaatgaactgggtccgccaggctccagggaagggactggagtgggtctcatccattactagtaccagtagttacatttattatgcagacccagtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 13532 JY8QFUQ01DAV2P productive Homsap IGHV3-33*04 F 833 87.16 190/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGNGYSYDDVVARWFDSW in-frame - cttctggattcaccttcagtaattacgcaatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtgacacgatatgacggagattataaattttatgctgactccgtgaagggccgcttcaccatttccagagacaattacaggaacaccctatatcttcaaatgaataacctgagagtcgaggacacggctgtctactactgtgcgcgaggaaatggatacagttatgatgacgtggtcgcgaggtggttcgactcctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13533 JY8QFUQ01BWN2X productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13534 JY8QFUQ01CSZL1 productive (see comment) Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt 83.49 182/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'GA' (2 nucleotides at position 70 to 71 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 113 in the user submitted sequence), (cause frameshift) gcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagGAtgggtcgcgggcaGtcaactggaatcggggcaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13535 JY8QFUQ01A5BMO No results 13536 JY8QFUQ01DT6YR No results 13537 JY8QFUQ01BELBS No results 13538 JY8QFUQ01B5NIQ No results 13539 JY8QFUQ01C3V22 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - gccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13540 JY8QFUQ01AIT6H productive (see comment) Homsap IGHV3-9*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKGDSGGYTHNYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaaggGgcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13541 JY8QFUQ01AWOCC productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13542 JY8QFUQ01BY2IV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 720 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CAKVKGYGGNWFQPHFDRW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattctccttcgaggggtctgtcgtgacctgggtccgacaggctccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaattccaaggacacggtctatctgcagatgaacggcctgagagtcgaagactcggcccgttattattgtgcgaaagtgaagggctacggcggcaattggttccagcctcactttgaccgctggggccagggcaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13543 JY8QFUQ01BHK6B productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13544 JY8QFUQ01BCXZT No results 13545 JY8QFUQ01AUWU9 No results 13546 JY8QFUQ01ATWGG productive Homsap IGHV3-11*01 F 828 87.1 189/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame + ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13547 JY8QFUQ01C5S8U productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13548 JY8QFUQ01AMWJR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-20*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'G' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccatcaccagttccagtgcttacatctactatgcagactcggtgacgggccgattcaccatctGccagagacaacgccaaggggtcactctatctgcacatcaacgaccttagggccgaggacacggctgtctattactgtgcgagtcttaacacgcacgcgggaccgggagccgagaggtctgcttttgatatctggggccgagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13549 JY8QFUQ01AD4KE productive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [2.16.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) gtctctggtggccccatcagcagcagcacttactactggacttggatccggcaggccgccgggagggactggagtggatcggacgtgtttatactTagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13550 JY8QFUQ01B1PWD unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 76 60.38 32/53 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13551 JY8QFUQ01BTLMP productive Homsap IGHV4-30-2*03 F, or Homsap IGHV4-39*01 F or Homsap IGHV4-39*05 F 674 91.3 147/161 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 X 7 13 X.7.13 [X.8.38.11] CARCGSYGSGSYYPW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ggaagggcctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtcgaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagatgtggttcttatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13552 JY8QFUQ01CXOIY unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 169 57.86 81/140 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13553 JY8QFUQ01DUJ59 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13554 JY8QFUQ01C39LJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13555 JY8QFUQ01BX74W productive (see comment) Homsap IGHV4-59*04 F (see comment) 729 82.03 178/217 nt 79.72 173/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [2.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'CCCAATGAA' (9 nucleotides at position 22 to 30 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'TGG' (3 nucleotides at position 42 to 44 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CAT' (3 nucleotides at position 67 to 69 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); gtcctttggtggctccatcagCCCAATGAAtaattacttccTGGggcgtggagtccgccaggccccCATgggaaggggcctggagtggattCggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccCaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13556 JY8QFUQ01ABAG4 productive (see comment) Homsap IGHV3-7*01 F 810 86.18 187/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'TGG' (3 nucleotides at position 64 to 66 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccaggggaggggcgTGGagagtgggtggcCcaacataaagtcagatggaagtgacaaatggtatgtggactccgtgaggggccCgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13557 JY8QFUQ01CT1B6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttc 13558 JY8QFUQ01CX9R2 productive (see comment) Homsap IGHV4-4*07 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [2.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'A' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); gtctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagccCcccactacaacccttccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccActttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13559 JY8QFUQ01BFRD4 No results 13560 JY8QFUQ01AA2UH No results 13561 JY8QFUQ01ANGEF productive Homsap IGHV4-4*07 F 817 87.32 186/213 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-22*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAGRNGNLAFNIW in-frame + tctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggagatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaaattgacttctgtgaccgccgcggacacggccatatattactgtgcgggaagaaatggaaatttggccttcaatatttggggccaagggacaaatgtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13562 JY8QFUQ01BP4DE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13563 JY8QFUQ01C4G5G productive (see comment) Homsap IGHV3-7*01 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.37.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 136 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcacatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13564 JY8QFUQ01C3M39 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CNTDLGGSWYTFYSDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 6 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) ctctggatacactgtcataaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13565 JY8QFUQ01DA81V No results 13566 JY8QFUQ01CKX1I productive Homsap IGHV3-9*02 F 837 87.56 190/217 nt Homsap IGHJ2*01 F (see comment) 157 77.36 41/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CARAPSVTFSGQGHYYDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cactggattcagctctgagaattatgccatgcactgggtccggcagcctccagggaagggcctagagtgggtctcacacatcagttggaatggcgaaggcatcgactacgcggactcagtgaagggccgattcaccgtctccagagacaacggcaagaattccctgtatttgcaaatgaacagtctgacaactgacgacacggccttgtattactgtgcaagagccccttcagtcacattcagcgggcaggggcactactatgatctctggggccgtggcaccctggtcgtggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13567 JY8QFUQ01DW642 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 458 88.79 103/116 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 2 X 0 14 X.0.14 [X.X.38.11] CPTPQNHDYIWGYDYW in-frame + tctggattcagcactccgtgaagggccgattcaccgtctccagagacaattccaagaacaccctgtatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtccgaccccccagaatcatgattacatttggggctatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13568 JY8QFUQ01DGNK9 No results 13569 JY8QFUQ01AIAC1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKGYHGPFDSW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gcctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggGggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13570 JY8QFUQ01CWH15 productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacctTggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13571 JY8QFUQ01A1DDB No results 13572 JY8QFUQ01APR7P productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13573 JY8QFUQ01B5BIZ No results 13574 JY8QFUQ01CQG05 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 803 85.07 188/221 nt 84.62 187/221 nt Homsap IGHJ5*02 F 110 69.39 34/49 nt Homsap IGHD1-26*01 F 2 8 10 5 8.10.5 [1.17.37.11] CREAIAW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) tctgggttcgtgttcggtaacttctttatgaattggttccgccagcctccgggaaaggggctggagtgggttggccgcatcaaaaccaaagttgatggtgagacaacagactacgctgcagccgtgaaagacagattcatcatttcaagagatgattcaaaaatacgatgtatctgcaaatgaacgacctgaagaccgaggacacggccgtatattattgtcgggaggccatcgcgtggggccagggaaccctggtcaaggtctcatcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13575 JY8QFUQ01CTGHQ productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13576 JY8QFUQ01CB5PE No results 13577 JY8QFUQ01AQGGH productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 979 93.69 208/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 10 15 8.10.15 [1.17.38.11] CATDRRGSTIAPQFDFW in-frame - tctggattcactttcagtagcgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaaacaaagctgacggtcagacaacagacttcgctgcacccgtgaaaggcagattcagcatctcaagagatgattcaaaaaccacactgtatctgcaaatgagcggcctgaaagccgaggacacagccatgtattactgtgccacagataggcggggttcgactatagcacctcaatttgacttctggagccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13578 JY8QFUQ01AMENX No results 13579 JY8QFUQ01AFH97 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 928 91.78 201/219 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARHNYGNEKYIMDVW in-frame - ggttttggatacaactttgccacctattggatcggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatggtctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13580 JY8QFUQ01APENP unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 13581 JY8QFUQ01CK7GH unproductive Homsap IGHV3-48*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttaGtagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13582 JY8QFUQ01A91GC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13583 JY8QFUQ01DEMZ0 unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGVVTA#LDYW out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13584 JY8QFUQ01BNEB3 productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13585 JY8QFUQ01CO34H productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 706 81.02 175/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [2.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame - Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13586 JY8QFUQ01CPYSE No results 13587 JY8QFUQ01ALQUJ productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13588 JY8QFUQ01CS746 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13589 JY8QFUQ01CV3MY unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRRGW*RADMMLLIS# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggatggtagcgggcagatatgatgcttttgatatctgggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13590 JY8QFUQ01CZFA8 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [1.17.38.11] CARASTLRYLDRW in-frame - tctctggtggctccatcagcagtgataattggtggagttgggtccgccagcccccagggaagggactggaatggattggggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13591 JY8QFUQ01CSZXL unproductive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F (see comment) 525 71.5 153/214 nt 71.03 152/214 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-3*01 F 1 8 7 X 8.7.X [1.17.38.11] LDAFDI# out-of-frame + Low V-REGION identity (71,50% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 60 of V-REGION: 9 nucleotides (from position 92 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccaggcttccgggaaaggactggagtgggttggccgtgtcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctgggccaggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13592 JY8QFUQ01CE8T4 productive Homsap IGHV1-58*01 F 876 90.19 193/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-12*01 F 3 8 8 16 8.8.16 [0.17.38.11] CAASASYNGYDTDAFDIW in-frame + tggattcacctttgattcctctgctgtgcagtgggtgcggcaggctagtggacaccgccttgagtggatgggatggatcgtcgttgccaatggtaagacagactacgcacggaatctccagggaagagtcaccattgccagggacatgtccacaagtacagtctacatggagctgagcagcctgaaatccgaggacacggccgtatattactgtgcggccagtgcttcgtataatggctacgatactgatgcttttgatatctggggcgaagggacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 13593 JY8QFUQ01DADW2 productive (see comment) Homsap IGHV3-48*01 F (see comment) 754 84.04 179/213 nt 82.63 176/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaAagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13594 JY8QFUQ01C7KS3 productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CATDRCTGGTCCPHYW in-frame + tggatacactttcaccagttattatatacactgggtgcgacaggcccctggacaggggcttgagtggatgggagttgtcaaccctggtgctgaatacacactctacgcacagaagttccagggcagactcaccttgaccagggacacgtccacgagcacagtctacatggagttgagtagcctgagatctgaggacacggccctgtattactgtgcgacagataggtgtactggtggtacctgctgtccacattactggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13595 JY8QFUQ01BTXVH No results 13596 JY8QFUQ01CEKIT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - gcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 13597 JY8QFUQ01A35NF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcCccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13598 JY8QFUQ01C2L8V productive (see comment) Homsap IGHV3-11*01 F 928 93.81 197/210 nt 91.9 193/210 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.16.37.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 92 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccaggaagggactggagtggtttcatgcatcactactagtggtaccacattctacacggactctgtgagggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13599 JY8QFUQ01AF28W productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 671 78.44 171/218 nt 77.98 170/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagAccccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13600 JY8QFUQ01A4LRU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13601 JY8QFUQ01A6CVK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CGKPIVGATGREMPVSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcGaactatgccatgaactgggtccgccaggttccagggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13602 JY8QFUQ01BKQCQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 677 95.3 142/149 nt 94.63 141/149 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 1 8 8.1.8 [1.1.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01BKQCQ ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 68 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtagctactggatgcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 13603 JY8QFUQ01AP4OP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAKVLAGATRDAYHYGMDVW in-frame + ctctggatttactttcagtaggtctgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggcattagtggtggtggtcttagcacatactacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacacgctgtttctgcaaatgaacagcctgagagccgaggacacggccacatattactgtgcgaaagtcctggcgggagctacgagggacgcctaccactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13604 JY8QFUQ01CX1W7 No results 13605 JY8QFUQ01BL5VZ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctGggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13606 JY8QFUQ01CFJEW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13607 JY8QFUQ01DT6BL productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 818 85.27 191/224 nt 84.38 189/224 nt Homsap IGHJ5*02 F 110 69.39 34/49 nt Homsap IGHD1-26*01 F 2 8 10 5 8.10.5 [1.17.38.11] CREAIAW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); cctctgggttcgtgttcggtaacttctttatgaattggttccgccagcctccgggaaAaggggctggagtgggttggccgcatcaaaaccaaagttgatggtgagacaacagactacgctgcagccgtgaaagacagattcatcatttcaagagatgattcCaaaaaatacgatgtatctgcaaatgaacgacctgaagaccgaggacacggccgtatattattgtcgggaggccatcgcgtggggccagggaaccctggtcaaggtctcatcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13608 JY8QFUQ01A9RBF productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKSPSQVGYYLDCW in-frame + ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13609 JY8QFUQ01AA57U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 725 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); cctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 13610 JY8QFUQ01C9SEI productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13611 JY8QFUQ01CZY8Q productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 965 95.28 202/212 nt 94.34 200/212 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [X.17.37.11] CASAPSDSSGYYFSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'GA' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) ggatacaccttcaccagttactatatgcactgggtccgacaggcccctggGAccaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccaggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13612 JY8QFUQ01CB2QO productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13613 JY8QFUQ01DOJJL No results 13614 JY8QFUQ01B1WH0 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + tctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13615 JY8QFUQ01BWJBZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaagctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcgaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13616 JY8QFUQ01AAQPQ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13617 JY8QFUQ01CRB82 No results 13618 JY8QFUQ01ATWCJ productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 13619 JY8QFUQ01DB4VJ unproductive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGYSYGCFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcagttttgcagactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactgggggccagggaatcctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 13620 JY8QFUQ01BZ1C1 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKEQEPHGHYVGTDY## out-of-frame + cgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgccgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13621 JY8QFUQ01BIGXB productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13622 JY8QFUQ01CPBDD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13623 JY8QFUQ01C8O27 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13624 JY8QFUQ01B65ND productive Homsap IGHV3-48*01 F 1075 99.54 215/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13625 JY8QFUQ01C065V productive Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13626 JY8QFUQ01B96WH productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13627 JY8QFUQ01DLC24 productive (see comment) Homsap IGHV4-61*01 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [2.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gtctctggtggctccgtcagcagtggtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13628 JY8QFUQ01BYP3F productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatTgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13629 JY8QFUQ01A8LX1 productive (see comment) Homsap IGHV3-9*01 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 7 8 26 7.8.26 [1.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) ctctggattcacctttgatgatttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13630 JY8QFUQ01B09S5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13631 JY8QFUQ01AHST6 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13632 JY8QFUQ01DP225 productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13633 JY8QFUQ01CZ0CN unproductive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAISSGFTRR#YW out-of-frame - ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 13634 JY8QFUQ01BD4S4 productive (see comment) Homsap IGHV3-11*01 F (see comment) 794 84.62 187/221 nt 84.16 186/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARYRGSYYDYGGVDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); caacctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggGggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13635 JY8QFUQ01CO82S productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13636 JY8QFUQ01CXXPG productive (see comment) Homsap IGHV4-39*02 F 978 94.09 207/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.16.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactggggctgggtccgccagccccagggaaggggctggagtggaTttgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13637 JY8QFUQ01AER3H No results 13638 JY8QFUQ01DNGXY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13639 JY8QFUQ01DDVRU No results 13640 JY8QFUQ01DL13S No results 13641 JY8QFUQ01DVVB9 No results 13642 JY8QFUQ01DPEHK productive (see comment) Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 99.09 217/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13643 JY8QFUQ01BKJ38 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13644 JY8QFUQ01B4O24 productive (see comment) Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD6-13*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARERQLNNGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtGgggtgacccacataaagcaagatggaagtgtcaaataccaagtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagagcggcagcttaataacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13645 JY8QFUQ01BTJ5H productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13646 JY8QFUQ01BFOPH unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F (see comment) 29 69.23 9/13 nt 8 8 X 8.8.X [0.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tggatacaccttcagcaacttctatatatattgggttcgacaggcccctggacaagggcttgattacataggagtattcaaccctagtggtggtaacaccaggtacgcacagaagttccaggacagagtcaccgtgaccagtgacacgtccacgaacacagtgtacatggagctgagtaggctgagatctgaagacacggccgtgtattactgtgcgagagggatagtggttactctgaatcggaaagtccgacaacccccaaaagactactgggggccagggaaccccgggtcatcgtctcctcagcttccaccaagggcccatccgtcttcccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13647 JY8QFUQ01BYIOI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13648 JY8QFUQ01C6ALY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacGaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13649 JY8QFUQ01C76AE productive (see comment) Homsap IGHV3-7*01 F 946 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD5-12*01 F 2 8 8 10 8.8.10 [2.17.38.11] CSLGAGWLTPHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcgcAttttagtacctattggatgaactgggtccgccaggttccggggaagggcctggagtgggtggccatcataaagcaagatggaagtgacatatcctatgtggactctgtgatgggccgattcaccatctccatagacaacgccaagaattcagtgtttctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgctctttaggcgctgggtggctaacaccacattgggggcggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacttcag 13650 JY8QFUQ01BANFC No results 13651 JY8QFUQ01AVFPO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); gcctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacaaAactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13652 JY8QFUQ01ABFMY unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 413 80.8 101/125 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 3 X X.3.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13653 JY8QFUQ01BSX5W unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccttggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13654 JY8QFUQ01CH14U No results 13655 JY8QFUQ01ARLEN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13656 JY8QFUQ01C0QKA unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13657 JY8QFUQ01CBO1C No results 13658 JY8QFUQ01BGJUC productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13659 JY8QFUQ01DJ3QI productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYHYDMFGDYW in-frame + cgctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaatgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgttcggcgactactggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 13660 JY8QFUQ01DQMDP No results 13661 JY8QFUQ01CQQPS unproductive (see comment) Homsap IGHV4-61*02 F 1005 95.45 210/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 2 10 7 X 10.7.X [1.16.38.11] CARAGETGLFGVVI#DDW out-of-frame - stop codons in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggtggctccatcggcagtggtagttattactggagctggatccgcagcccgccgggaagggactggaataccttgggcgtatctataccagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcgggggaaacaggactttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13662 JY8QFUQ01BGOPQ productive Homsap IGHV3-13*01 F 872 89.77 193/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 7 9 8.7.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 13663 JY8QFUQ01A688N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13664 JY8QFUQ01BMP31 No results 13665 JY8QFUQ01B98BJ productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttagacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13666 JY8QFUQ01AGY03 No results 13667 JY8QFUQ01AWR6X No results 13668 JY8QFUQ01B28RE No results 13669 JY8QFUQ01BSR1C productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - cctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13670 JY8QFUQ01B6BOW productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13671 JY8QFUQ01C6MOM unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 536 71.56 156/218 nt Homsap IGHJ1*01 F (see comment) 22 75.0 6/8 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (71,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13672 JY8QFUQ01C3EQE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13673 JY8QFUQ01CSECT productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13674 JY8QFUQ01CATOK productive Homsap IGHV4-59*03 F 935 93.02 200/215 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGLYYYTSGYPHDAFDVW in-frame - tctctggtgactccatcaatgcttactattggagctggattcggcagtccccagggaagggactggagtggattggacatgtctattatagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacatatccaagaaccaattctccctgaagctgaactctgtgaccgctgcggacacggccgtgtatcactgtgcgcgggggctctattattatactagtggttatccccatgatgcttttgatgtctggagccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13675 JY8QFUQ01DG853 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVGLMSARDRIDYW in-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtggggctgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13676 JY8QFUQ01C1AIH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13677 JY8QFUQ01BB93X productive (see comment) Homsap IGHV1-2*04 F 925 92.96 198/213 nt 92.49 197/213 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 14 8.8.14 [0.17.37.11] CTRDTSLDNGAALDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tggatacaccttcaccgactactatatgcactgggtgcgacaggccccaggacaagggcttgagtggatgggatggatcaaccctaaaagtggcggcacaaattatgcacggaagtttcaggctgggtcaccatgaccagggacacatccatcaacactgtctacatggagttgagcaggttgaaatctgacgacacggccatttattactgtacgagggatacttctttggacaacggagccgctcttgatatttggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13678 JY8QFUQ01CDRDD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13679 JY8QFUQ01B832O productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgcctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13680 JY8QFUQ01ADD9Y unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 96 95.24 20/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcacctttagtac 13681 JY8QFUQ01BQMNN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13682 JY8QFUQ01BPXDU unproductive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPFTVTTGKDAY## out-of-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13683 JY8QFUQ01CHKB6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKSPDFGGNP#YFDFW out-of-frame - ctctggattcgccttcaccagctatgccatgacctgggtccgccaggccccagggaaggggctggaatgggtctcttctattagtggcagtggtgcgaccacatactacgcagactccgtgaagggccgcttcaccacctccagagacaattccaagaacacggtgtatctgcaaatggacagcctgagagccgcggacacggccgtctattactgtgcgaaaagtcccgacttcggtggtaaccctcctactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13684 JY8QFUQ01BNQ6N productive Homsap IGHV3-23*03 F (see comment) 894 91.12 195/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BNQ6N ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttggttattatggcatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13685 JY8QFUQ01APK7S productive (see comment) Homsap IGHV4-34*06 F (see comment) 682 80.19 170/212 nt 79.72 169/212 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 7 7 14 7.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tccatggtgggtccctcagggttaccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacctagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13686 JY8QFUQ01CV9Y0 No results 13687 JY8QFUQ01AGXFM unknown (see comment) Homsap IGHV4-61*02 F (see comment) 270 58.06 126/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (58,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaacccctcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 13688 JY8QFUQ01AGMKR productive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 873 89.4 194/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame + ctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13689 JY8QFUQ01CNUO2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13690 JY8QFUQ01ADNKP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); ctctggattcagatttagcagctatgccaAtgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13691 JY8QFUQ01BS2U1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'N' (1 nucleotides at position 137 to 137 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccNatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13692 JY8QFUQ01AN28Z No results 13693 JY8QFUQ01DIT1N No results 13694 JY8QFUQ01CHKF0 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13695 JY8QFUQ01AC5GC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccgtcagcagtggtaattactactggaactggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13696 JY8QFUQ01BSDZV productive (see comment) Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt 79.72 173/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.37.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 204 in the user submitted sequence), (cause frameshift) catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacgctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13697 JY8QFUQ01BERHM unproductive Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [0.17.38.11] CARGGRRGNYYWGILTP# out-of-frame - in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacGaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattggggaatcttgactcctggggccaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13698 JY8QFUQ01DKUF5 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ggcctcctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13699 JY8QFUQ01C819B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKKHYNSGTYLYNFDYW in-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13700 JY8QFUQ01CE3GD unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.16.38.11] CTRTQFDPDYGDYETGYGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) gcggctggattcaacttccgatcttatgccatgtactgggtccgccaggcccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatacagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctgggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13701 JY8QFUQ01CWV4R productive (see comment) Homsap IGHV3-48*02 F 628 94.33 133/141 nt 93.62 132/141 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 X 14 8.X.14 [1.2.35.11] CAKDRGGSAYPIFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaccttcggcagttataggatgagctggactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13702 JY8QFUQ01B5K7F No results 13703 JY8QFUQ01C73WM unproductive Homsap IGHV3-74*03 F (see comment) 702 80.65 175/217 nt 80.18 174/217 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRGTTGWRGVDY## out-of-frame - Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcaacgtcagtggatactggatgcactgggtccgccaagtgccagggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactgggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13704 JY8QFUQ01BX8L0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 602 91.61 131/143 nt 90.91 130/143 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 8 X 14 8.X.14 [2.2.35.11] CATDRLRGDKYNFDDW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctataccttgagttggatgcagtgaagggccgattcaccatttccagagacaacgccaagaactccctctctctgcaaatgaacagcctgagagccgaggacacggcagtatattactgtgcgaccgaccgccttcgtggagataaatacaattttgacgactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13705 JY8QFUQ01AP7Z9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13706 JY8QFUQ01BNNOK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 859 88.02 191/217 nt 87.1 189/217 nt 8 8 X 8.8.X [2.16.38.X] null - No rearrangement found in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 2 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaacgtggtccgccaggctccagggaaggggtgagtgggtctcatccattagtagtagtagtanttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaAatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13707 JY8QFUQ01AQQ0A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 994 95.83 207/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - tctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13708 JY8QFUQ01DPB8X unproductive (see comment) Homsap IGHV4-55*03 P (see comment) 644 77.42 168/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHSRLVRYFEF## out-of-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DPB8X ; 9 AA in Homsap_IGHV4-55*03), and low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgttgacgccataagcgacctcggttatttctgggcctgggtccgccagcccgccgcgaagggactggagtggatcggacatgcccttggtgatggatataccgaatacaaccccgccctagagagtcgaatcaccgtgtcagtggacaagtccaagaaccagttttccctgacgttggagtccgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13709 JY8QFUQ01BOGFB productive Homsap IGHV3-64*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 13710 JY8QFUQ01B0WZ3 No results 13711 JY8QFUQ01B1TCN productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 846 88.02 191/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [2.17.38.11] CAREFRAPSLARYGMDVW in-frame - gcctcgggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcaatatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13712 JY8QFUQ01BALA1 No results 13713 JY8QFUQ01C80EU productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13714 JY8QFUQ01COICN unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 13715 JY8QFUQ01BX0HR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); cctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13716 JY8QFUQ01ALB0B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 760 83.8 181/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13717 JY8QFUQ01CAGWR No results 13718 JY8QFUQ01BFDI8 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag 13719 JY8QFUQ01BCE7A productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 912 90.13 201/223 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-24*01 ORF 3 8 10 17 8.10.17 [1.17.38.11] CSRGLGDGYNLGYHALDIW in-frame - ttctggattcagttttggtgattattctatgatctggttccgccaggcaccggggaaggggctggagtgcgtaggtttcattagaagcagagcatatggtgggacaacacaatacgccgcgtctgtgaaagacagattcaccatctcaagagatgatcccaaaggcatcgcctatttgcaaatgagcagtctgaaagtcgacgacacaggcgtgtatttttgtagtcggggattaggcgatggctacaatctgggttatcatgcccttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13720 JY8QFUQ01BOEIY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccag 13721 JY8QFUQ01DFZ5B No results 13722 JY8QFUQ01BG466 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F (see comment) 302 75.23 82/109 nt 8 10 X 8.10.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (75,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggtcgtcgcatgcctggtccagggcttcttccccca 13723 JY8QFUQ01B9KLC No results 13724 JY8QFUQ01CD5QQ No results 13725 JY8QFUQ01ACV4H productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 13726 JY8QFUQ01DAB4Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKKHYNSGTYLYNFDYW in-frame - ctctgggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13727 JY8QFUQ01B6QSK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 455 87.29 103/118 nt 8 8 X 8.8.X [1.17.4.X] null - No rearrangement found cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcttccccca 13728 JY8QFUQ01A4IQR productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 903 91.59 196/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARRDVGSHAFDLW in-frame - tggatacaattttaactacgactggatcggctgggtgcgccagatgctcgggaaaggcctggagtggatggggatggtctatgttggtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 13729 JY8QFUQ01COLCX productive (see comment) Homsap IGHV3-7*01 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 7 9 8.7.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggcgtggagtgggtggccaacataagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13730 JY8QFUQ01BYTJB productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13731 JY8QFUQ01AVB8N productive (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 737 82.79 178/215 nt 82.33 177/215 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD6-6*01 F 1 8 8 21 8.8.21 [1.17.38.11] CAKDLGYSISSGASTHYYGMGVW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01AVB8N ; 7 AA in Homsap_IGHV3-69-1*01), and low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcgcctTttggtgactatgccatgaactgggtccgccaggctccagggaggggcctggaatgggtctcatttgtcaccactactggcagttccacatattatgcagactccgtgaagggccgattcaccgtttccagagacgacgccaagaatctactgtatcttcagatgaccggcctgagagacggggacacggctacatattactgtgcgaaagacttggggtacagcatctcgtcgggggcctccacgcactactacggaatgggcgtctggggccaagggacaacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13732 JY8QFUQ01CO8FJ productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 955 91.23 208/228 nt 90.79 207/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 19 10.9.19 [2.17.38.11] CARASRRDRLSDKNYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcaacagtgccacttggagctggatcaggcagtccccaacgggacgccttgagtggctgggaaggacttactacaggtccaaatggtataatgattatgcggtgtctgtgAaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtctctctgataagaactactatgaactggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13733 JY8QFUQ01CXM37 productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13734 JY8QFUQ01AFSQR unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGV*QWL##DFDCW out-of-frame - stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); tctggattcacctttagtagatttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtcGtcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13735 JY8QFUQ01A7137 No results 13736 JY8QFUQ01CYX8Z No results 13737 JY8QFUQ01AP7QS unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDLRGSTMASD#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaaggggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13738 JY8QFUQ01BG66A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13739 JY8QFUQ01BLP66 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13740 JY8QFUQ01CJAOV productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARFSGSYKSAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); gttctggatacatctttaccgactattggatcggctgggtgcgccagacggccgggaaAaggcctggagtggatggggaAtcatctatcctggtgactctgacaccagttatggcccgtccttccaaggccaggtcaccatttcagccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13741 JY8QFUQ01A129D No results 13742 JY8QFUQ01DCH36 No results 13743 JY8QFUQ01B2TNY unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F (see comment) 264 72.38 76/105 nt 8 8 X 8.8.X [0.17.1.X] null + No rearrangement found Low V-REGION identity (72,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccgaccactatctgcactgggtccgacaggcccctggacaagggcttgagtggatgggaacgtggtcatcgcctgcctggtccagggcttc 13744 JY8QFUQ01B3AED unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaaggggaccacggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13745 JY8QFUQ01BG866 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*02 F 109 70.21 33/47 nt Homsap IGHD5-12*01 F 3 8 8 6 8.8.6 [1.17.38.11] CVSIGHGV in-frame + cctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtcgcacacattgacactgatgggagtatcgcagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatactttgtatctgcaaatggacagtctgagagccgacgacacggctatatattactgtgtaagcattggacacggagtgggcccgggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13746 JY8QFUQ01CI9RK No results 13747 JY8QFUQ01BIN5M No results 13748 JY8QFUQ01BAD9W productive (see comment) Homsap IGHV3-30*01 F 996 95.0 209/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); ggcctctggattcaccttcaatacctattcGtatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13749 JY8QFUQ01DS5YQ unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13750 JY8QFUQ01BHEWJ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13751 JY8QFUQ01C9UKO productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13752 JY8QFUQ01A2AVP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13753 JY8QFUQ01CKJ3B No results 13754 JY8QFUQ01BQSY3 productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctca 13755 JY8QFUQ01BCRG1 No results 13756 JY8QFUQ01DP380 productive Homsap IGHV3-33*02 F, or Homsap IGHV3-33*03 F 148 65.43 53/81 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 X X 14 X.X.14 [X.X.27.11] CATDDSNGWDEVADYW in-frame - gcctctggattcaccttcagctcccattggatgagctggatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13757 JY8QFUQ01DNJEO productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13758 JY8QFUQ01CQIXM productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttTgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13759 JY8QFUQ01AZ08S productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.17.38.11] CVRLDYYGSGSSYSGLDYW in-frame + tgtctggtggctccatcagtggtactccttactactggggctggatccgccagcccccaggtaaggggctggagtggattgggcatgtatatcacagagggaccacctactacaacccgtccctcaagagtcgagtcgccatatccgtagacacgtccgagaaccggttctccctgcagttgaactctgtgaccgccgcagacacggctgtatattactgtgtgagactggattactatggttcgggaagttcttatagtggccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 13760 JY8QFUQ01DLTW9 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13761 JY8QFUQ01BMYZK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13762 JY8QFUQ01BAGOW productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 928 89.91 205/228 nt 89.47 204/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 3 10 9 19 10.9.19 [2.17.38.11] CARSSRRDRLSDRNYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatactacaggtccaaatgggatactgattatgcggcgtctgtgAaaaagtcgaataaccctcaccccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattattgtgcaagatcttccagacgcgatcgtttgtctgataggaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13763 JY8QFUQ01CI3EW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13764 JY8QFUQ01CL0CL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 689 79.82 174/218 nt 79.36 173/218 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD5-24*01 ORF 3 8 8 15 8.8.15 [2.17.37.11] CASGGNAYITRRGLEVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) gcttccggcttcaccctcagtaaacactggatgcattgggtccgccagccttcagggaagggcctggagtttgtcgcgcgtctgagtaatgatggatataccacaagttatgcagactccgtgcagggccgcttcactatctccagagacgccgccgcgaacgcgctgttttgcagttgaccggtctgagagccgacgacacgggtgtctattactgtgcaagtgggggaaatgcctacatcacgcggcgtggtctggaggtctggggccgggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13765 JY8QFUQ01CG4QN productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame + cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13766 JY8QFUQ01B4C0K productive Homsap IGHV3-7*01 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaaatgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13767 JY8QFUQ01A9WD5 unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDG#YW out-of-frame - ctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13768 JY8QFUQ01AG5VW productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 90 to 95 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13769 JY8QFUQ01A7FPX productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 13770 JY8QFUQ01DJUOR unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF or Homsap IGHV3-23*01 F or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 143 75.0 39/52 nt 8 X X 8.X.X [1.8.X.X] null - No rearrangement found ctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggcccca 13771 JY8QFUQ01BB0UL No results 13772 JY8QFUQ01BQZSZ No results 13773 JY8QFUQ01CZ1K4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 861 88.18 194/220 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGG# out-of-frame - aggctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13774 JY8QFUQ01BAT4C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13775 JY8QFUQ01DKRX5 productive Homsap IGHV3-7*01 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13776 JY8QFUQ01B9UE1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13777 JY8QFUQ01BWLWN No results 13778 JY8QFUQ01C0Q01 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 13779 JY8QFUQ01CP0F3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13780 JY8QFUQ01AYACL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13781 JY8QFUQ01B7Q4P productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggGggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13782 JY8QFUQ01CJTTF productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaccacttactacatcagctggctccggcagcCccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccga 13783 JY8QFUQ01ACMD4 No results 13784 JY8QFUQ01B0E0W productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt 94.93 206/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.16.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaagggctggagtggatttcatacattagtagtagtgGgtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13785 JY8QFUQ01BVNW1 productive Homsap IGHV4-34*13 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 7 13 8.7.13 [1.17.38.11] CASRSRGYSYGYDYW in-frame + ctatggtgggtccttcagtggttactactggagctggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagccgctcacgtggatacagctatggttacgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc 13786 JY8QFUQ01ANI1H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13787 JY8QFUQ01AREZ5 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13788 JY8QFUQ01DBD13 No results 13789 JY8QFUQ01BB9BO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13790 JY8QFUQ01AQA3U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame + ttctggattctcctttagcaactatgccctggcctgggtccgccaggctccagggaaggggctggagtgggtctcaattgttagtggaagtggtactggcacaggccacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcgcgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13791 JY8QFUQ01BPN3Y unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 805 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [1.17.37.11] CARDNVTFWDAFDIW# out-of-frame - in FR3-IMGT, from codon 86 of V-REGION: 1 nucleotides (from position 163 in the user submitted sequence), (cause frameshift) gtctgggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatttggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcacctatatttacaaatgaatagcctgagagtcgaggacacggctgtgtattactgcgcgagagataatgtcaccttttgggatgcctttgatatttgggggccggggggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13792 JY8QFUQ01CCFDS productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13793 JY8QFUQ01AKI3X No results 13794 JY8QFUQ01CR04E productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13795 JY8QFUQ01CH8DM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13796 JY8QFUQ01AVTVF unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [4.17.38.11] CARGAPFS**# out-of-frame + stop codons cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13797 JY8QFUQ01CMG8J unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 874 93.03 187/201 nt 92.54 186/201 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-2*01 F 2 10 1 X 10.1.X [1.17.37.11] CARVA*CDFVVEPTAQGL#YSYDMDVW out-of-frame + stop codons in CDR2-IMGT, from codon 57 of V-REGION: 19 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) ctctggtggctccatcaacaatagtacttactactacggctgaatccgccagccccccgggaaggggctggagtggattgggagtctctctacaacccgtccctcatgagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgccgacacggctgtatatcgctgtgcgagagttgcctgatgtgattttgtggtagagccaactgctcaaggccttagtactcctacgatatggacgtctggggccaagggaccacggacgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13798 JY8QFUQ01A2Q7N productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13799 JY8QFUQ01DWIOH productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 939 91.48 204/223 nt 91.03 203/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 2 8 10 9 8.10.9 [1.17.38.11] CNTWLGPSDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 75 of V-REGION: 'A' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); ctctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacAagattcaccatttcaacagatgattcaaaaaacacgttgtatctcctaatgaacagcctgaaaaccgaggacacagccgtctattactgtaacacctggctaggacctagtgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13800 JY8QFUQ01AFCKU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaGggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13801 JY8QFUQ01A3O28 No results 13802 JY8QFUQ01BR32F productive Homsap IGHV3-7*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13803 JY8QFUQ01A5NHA productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ1*01 F (see comment) 80 61.54 32/52 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKRWAGGLAGTLSSG in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); gtctggattcagtttcagtgactatgccatgcactgggtccgccagactccaggcaaggggctggagtgggtggcagttatttcatatgatgggagagagaagtactatgcagactccctgaagggccgattcaccacctccagagacaactccaagAaaaatgctgtatctccaagtgaatagcctgagacctggagacacggctgtgtattactgtgcgaaaagatgggccggggggttggctggtacgctgagcagtggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13804 JY8QFUQ01B2AOD No results 13805 JY8QFUQ01DIXL8 No results 13806 JY8QFUQ01CLQ5W No results 13807 JY8QFUQ01C8V86 unproductive Homsap IGHV4-61*03 F, or Homsap IGHV4-61*08 F 866 88.24 195/221 nt Homsap IGHJ5*01 F 84 62.75 32/51 nt Homsap IGHD5-24*01 ORF 2 10 7 X 10.7.X [1.17.38.11] CARLRRMVPVSTYYYHSLDV## out-of-frame + tctccggtgcctccgtcaactatgatgcttactactggagttggatccggcagcccccagggagtccactggagtggattgggtatgcccatcacagtgggagcaccaactacaacccctccctcaggagtcgagtcaccatttcagttgacccgtcgaagaataacttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacttcgaaggatggttccagtttcgacctactactaccacagtttggacgtctggggccaaagggaccacggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13808 JY8QFUQ01CK0BJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKSIIIRGLI#YNFDYW out-of-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13809 JY8QFUQ01A0EF3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13810 JY8QFUQ01CSWAL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13811 JY8QFUQ01CQI4A productive Homsap IGHV3-9*01 F 990 95.39 207/217 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtggatctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13812 JY8QFUQ01AWL6G productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13813 JY8QFUQ01A5YFY productive (see comment) Homsap IGHV3-23*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcccctttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13814 JY8QFUQ01B1VIH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtaattactGggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13815 JY8QFUQ01A8A7H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13816 JY8QFUQ01DFQI1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13817 JY8QFUQ01BRQXE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 13818 JY8QFUQ01DGMP9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13819 JY8QFUQ01DLVME productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13820 JY8QFUQ01AICL6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 989 95.81 206/215 nt 94.42 203/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARYRGYQSYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tctctggtggctccaGtcagtCagttactactggagctggatccggcagcccccagggaagggactggagtGggattgggtatatctcttacagtgggggcaccaattacaatccctccctcaagagtcgagtcgccatatcaggagacacggccaagaaccagttctccctgaagctgaactctgcgaccgctgcggacacggccgtgtattactgtgcgcggtataggggttaccagagctactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13821 JY8QFUQ01DD8MX unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 689 79.82 174/218 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLGLNAVYAFDV## out-of-frame + stop codons Low V-REGION identity (79,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtaggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctgggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13822 JY8QFUQ01AXIAU productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13823 JY8QFUQ01BZ88U productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13824 JY8QFUQ01BE57F productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARTEYVSGWYIGGFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctatggtgggtcactcagttcttatttctggagctggatccgccagtccccagAgaaaaggactggagtggattggggaaatcaatcagagtggaaccaccaactacaacccgtctctcaggagtcgagtcaccatagcaatagacacgtccaagaaccagttctccctgaaggtgacctctgtgtccgccgcggacacggctgtctattactgtgcgaggaccgagtatgtcagtggctggtacatcggggggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggcaactcag 13825 JY8QFUQ01AMVGJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt 91.67 198/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'GC' (2 nucleotides at position 133 to 134 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 142 to 142 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggacGtccgtgcagggccggttGCgaccatcCtccagagacaattcgaagaaTcacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13826 JY8QFUQ01BTH1P No results 13827 JY8QFUQ01DJQDX productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13828 JY8QFUQ01BO9N8 unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD2-15*01 F 1 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW# out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcag 13829 JY8QFUQ01ASM4O productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13830 JY8QFUQ01BX0CV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggGggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13831 JY8QFUQ01ATUET productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13832 JY8QFUQ01ALDNJ unknown (see comment) Homsap IGHV1-58*01 F, or Homsap IGHV1-58*02 F or Homsap IGHV3-11*01 F or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F 50 100.0 10/10 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found tctggattca 13833 JY8QFUQ01BJBC7 productive (see comment) Homsap IGHV3-11*01 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CTRDDRSVRGVTSDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatTttttgtacgagagatgatcgctcggttcggggagtcacctcagactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13834 JY8QFUQ01AIZD8 No results 13835 JY8QFUQ01CNQ50 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 956 92.76 205/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 7 10 10 7.10.10 [1.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13836 JY8QFUQ01BNDM6 No results 13837 JY8QFUQ01DIKDT productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSAPWNDHW in-frame + tctctggtggctccatcagcagcggttattactactggagctggatccggcagcccgccggggagggactggagtgggttgggcgtatctctgccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatatcagtgaacacgtccaagaaccagttctccttgaggctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagacaaggggacagtagtgctccctggaatgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13838 JY8QFUQ01B3HMA productive (see comment) Homsap IGHV4-61*02 F 883 89.5 196/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaAacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13839 JY8QFUQ01CPJVI productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13840 JY8QFUQ01BQY9M unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGV*QWL##DFDCW out-of-frame - stop codons cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13841 JY8QFUQ01AVBCS productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 23 to 24 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaatagGAaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13842 JY8QFUQ01CZ4DS unproductive (see comment) Homsap IGHV3-30*01 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-10*02 F 2 8 8 X 8.8.X [1.17.38.11] CARDAQC*##YYYYGMDVW out-of-frame + stop codons cctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaagtaataaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgagagatgcccaatgttaggcactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 13843 JY8QFUQ01BHG5A unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*02 F 1 8 8 X 8.8.X [1.17.38.11] CVRVPTQWFPPSTLTLTS# out-of-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagttcctatagcatgagctgggtccgccaggctccggggaagggcctggaatgggtctctgctatcagtggcagcgatgatcgcacatcttatgttgactccgtgaagggccgcttcaccatctccagagacacttccaggaatacactgtttctgcagatgaacagcctgagcgccgaagatacggccacatacttttgtgtgagagtccccactcagtggtttccaccttccacactcactttgacatctgggccagggaaccgtggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 13844 JY8QFUQ01BZXCM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD6-25*01 F 1 8 8 22 8.8.22 [1.17.38.11] CARYQGDTSGYQDVFYAHYGMDVW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacttttaggggctactggatgcactgggtccgtcaggttccaggtaaggcgccggagtggctcgcacgtctgaatactgatggagatagtacaagttatgcggactccgtgaagggccgcttcaccatctccagagacaacgccaggagcacattgttcctgcaaatgagcagtctgagagtcgaagacacggccatttattactgtgcacggtatcagggcgataccagtggctaccaggacgttttctacgcccactacggtatggacgtctggggccaagggacctcggtcaccgtctattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13845 JY8QFUQ01BB6OG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-3*01 F 3 8 8 8 8.8.8 [1.17.38.11] CAKDMAFMEG in-frame + cctctggattcacctttagcgactatgccatgagctgggtccgacaggctccagggaagggcctggagtggctctcaagtattagtggtcgcggtttaagcacctactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacaccttgcatttgcaaatgagcagtctgagagccgacgacacggccatatattattgtgcaaaagatatggcttttatggaggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggctnttcccc 13846 JY8QFUQ01CJZKY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt 82.03 178/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcccctttagtgtgtactggatgtactgggtccgccAaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagagcttcttccccca 13847 JY8QFUQ01B4L9U unproductive Homsap IGHV3-7*03 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-11*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARDRYSSDSSYYMPNWLD#PG out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggGggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgaccccctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 13848 JY8QFUQ01DWBVC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagAttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13849 JY8QFUQ01CWXW5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13850 JY8QFUQ01BFTMS unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 269 72.64 77/106 nt 8 7 X 8.7.X [1.17.1.X] null - No rearrangement found Low V-REGION identity (72,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttccccca 13851 JY8QFUQ01AX32U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.49 182/218 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-1*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKSRRDWNDEGDVYDVW in-frame + Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctctggattcatctttagagagtttgccatgacatgggtccgccaggctccagggaaggggctggagtgggtctcatttattgatcatagtgggaatgtcaaacgctacgcagacaccgtgaagggccggttcagtatatccagagacaactccaggaacatgttctatctagaagtgaacagcctgagagccgaggacacggccgtatattattgtgcgaaatcccgtcgagactggaacgacgagggtgatgtttatgatgtctggggccgagggacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13852 JY8QFUQ01CVOKK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 771 83.64 184/220 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ttccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcaagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13853 JY8QFUQ01B0KK3 productive Homsap IGHV3-7*01 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARTSSREITDYW in-frame - gcctctggattcacctttggtagctattggatgcgtcgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13854 JY8QFUQ01A6JRT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13855 JY8QFUQ01AJTT0 No results 13856 JY8QFUQ01B1QWY productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARFSGSYKSAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gttctggatacatctttaccgactattggatcggctgggtgcgccagacggccgggaAaaggcctggagtggatgggaatcatctatcctggtgactctgacaccagttatggcccgtccttccaaggccaggtcaccatttcagccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13857 JY8QFUQ01C1F3C No results 13858 JY8QFUQ01C6SW6 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 710 91.12 154/169 nt 8 7 X 8.7.X [1.17.22.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01C6SW6 ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 13859 JY8QFUQ01CVNUO No results 13860 JY8QFUQ01BF6AT unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 962 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 7 8 17 7.8.17 [1.17.38.11] CA*KKHYNSGTYLYNFDYW in-frame - stop codons in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tctggattcacctttagcaactttgcatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagAcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgtaaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13861 JY8QFUQ01B8SWC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13862 JY8QFUQ01AXWGT productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13863 JY8QFUQ01CP8N2 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [2.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gtctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13864 JY8QFUQ01AHGB3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13865 JY8QFUQ01BW7CO No results 13866 JY8QFUQ01BKMBL No results 13867 JY8QFUQ01AEL9L No results 13868 JY8QFUQ01AYXP4 productive (see comment) Homsap IGHV4-61*02 F 974 93.67 207/221 nt 92.76 205/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccCttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtaaGcccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13869 JY8QFUQ01CVPXO No results 13870 JY8QFUQ01BGYJV productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.45 188/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.16.38.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13871 JY8QFUQ01CQHUH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13872 JY8QFUQ01C8UIH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 13873 JY8QFUQ01B9O1F productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARAKLAGDGANWYFDLW in-frame - cctctggattcacccttagtagttattggatgaactgggtccgccaggttccagggaaggggctggagtgggtggccaacatacaccaagatggaagtgagacatattatgtggactctgtgaagggccgattcaccgtctccagagacaacgcgaggaactcactgtatctgcagatgaacaacttgaaagtcgatgacgcggctgtgtattactgtgcgagagcgaagttagcaggagatggtgcaaactggtacttcgatctctggggccgtggcactctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13874 JY8QFUQ01BP08J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 13875 JY8QFUQ01BYKXO unproductive (see comment) Homsap IGHV3-9*01 F 792 85.25 185/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CGRIAKPGLGALDL## out-of-frame + stop codons cgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggcccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccaa 13876 JY8QFUQ01BRLSG productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13877 JY8QFUQ01ADDDA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARADNYDSLGLKFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtaactacCtggaactggatccggcagcccccagggaagggactggagtggattgggtatatctatcacagtgggagcaccagctacaacccctccctcaggagtcgagtcaccatatcattagacacgtccaagaaccagttctccctgaaactgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggcggataattatgatagtcttgggctgaagttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13878 JY8QFUQ01CYDQV productive Homsap IGHV3-48*03 F 850 88.43 191/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + tctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13879 JY8QFUQ01BJ3YM unproductive (see comment) Homsap IGHV4-4*07 F (see comment) 692 80.47 173/215 nt 79.53 171/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-16*01 F 2 8 7 X 8.7.X [1.17.38.11] CARERGLSIGGAREF*LL# out-of-frame + stop codons Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'ACCGAT' (6 nucleotides at position 18 to 23 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'GATGGATACACCAAGAATGATCCTTCCCTCAGGAGTCGA' (39 nucleotides at position 102 to 140 in the user submitted sequence), (do not cause frameshift); tctctggtggcgccatcACCGATactgactccttctggagctggattcggcagcccgccgggagcggtctggagtggatcggacgtgtttataatagtgggGATGGATACACCAAGAATGATCCTTCCCTCAGGAGTCGAatcaccaactacaatccttccctcaggggtcgaatctccatgtcagtggacacgtccaagaatcagtttctcttgaccttgaaatctgtaatcgccgaagacacagccgtctattattgtgcgagagaacgtggtctttcgattggcggagcgagagaattttgactcctggggcccagggaaccctggtcaccgtctcctcggcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 13880 JY8QFUQ01DEX6Z productive (see comment) Homsap IGHV4-61*02 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [0.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13881 JY8QFUQ01A2AEH productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGSSGFNDAYFDNW in-frame + ctccggattcacctttaacacttattggatgaactgggtccgccaggctccagggaagggactggagtgggtggccaacataaaccaagatgggagcaggagacactatgtggactctgtgatgggccgattcaccatctccagagacaacaccaaggactcactgtatctgcaaatggacagcgtgagagccgaagacacggctgtctattactgtgcgaggggatctagtggattcaacgacgcctattttgacaactggggccagggaaccctggccacagtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggtcttcttcccccaag 13882 JY8QFUQ01B9TMK productive Homsap IGHV4-61*02 F 853 86.94 193/222 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [2.17.38.11] CARGMATIKTVRFDPW in-frame - gtctctggtggctccatgaggagtggaattaattcctggacatggatccggcagcccgccgggaagggactggagtggattgggcgtatctatatcaatggagacaccaactacaatccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaaacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13883 JY8QFUQ01CLUK6 unproductive Homsap IGHV3-48*01 F (see comment) 752 82.57 180/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDPREGA#FFDYW out-of-frame - Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggggttcagtcttaatacatatagtatgaattgggtccgccagattccagggaaggggctggagtgggtagggtacattagtagtactgggaataccatatattacgcagactctgtgaggggccgattcaccatctcccgcgacattgccgaaaattcactgtatctgcaaatgaatagcctgacacccgacgacacggctgtctattactgcgcgagagatccccgagagggggcaccttctttgactactggggccggggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13884 JY8QFUQ01CC9JY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13885 JY8QFUQ01B3MK5 productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CATDRCTGGTCCPHYW in-frame + tggatacactttcaccagttattatatacactgggtgcgacaggcccctggacaggggcttgagtggatgggagttgtcaaccctggtgctgaatacacactctacgcacagaagttccagggcagactcaccttgaccagggacacgtccacgagcacagtctacatggagttgagtagcctgagatctgaggacacggccctgtattactgtgcgacagataggtgtactggtggtacctgctgtccacattactggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13886 JY8QFUQ01CQD9H productive (see comment) Homsap IGHV4-59*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [2.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); gtctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13887 JY8QFUQ01CIMH5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13888 JY8QFUQ01COXUM No results 13889 JY8QFUQ01B55T7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P (see comment) 429 84.3 102/121 nt Homsap IGHJ6*02 F (see comment) 94 61.29 38/62 nt Homsap IGHD6-6*01 F 2 X 2 17 X.2.17 [X.X.38.11] CVRDLAARPPYYYYGMDVW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcaactcagtgaagggccgattcaccatctccagagacgactccaagaactcactgtttctgcagatgaacagcctcagagccgaggacacggctgtttattattgtgtgagggatttggcggctcgtcccccttattattactacggtatggacgtctggggccaggggccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13890 JY8QFUQ01A3KZK unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGTREWSGIDY## out-of-frame + cctctggattcattttcagtaactactggatgcactgggtccgccaagctccagggaaggggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactactggggtcaggggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 13891 JY8QFUQ01BYZK6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13892 JY8QFUQ01BI7JX productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13893 JY8QFUQ01B8LS6 unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDELPWDTIEYY#LDYW out-of-frame + ctctggattcaccttcagtacctattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaaaaaaaaggtattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttggactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13894 JY8QFUQ01A0XQ3 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13895 JY8QFUQ01DJ02O productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13896 JY8QFUQ01CKFEF productive Homsap IGHV3-30*06 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVRVSGGDGVNW in-frame - tctggattcaccttcagtacctctggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatttcatatgatggaagtagtaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctgtttctacaaatgagcagcctgagacctgaggacgcggcgatgtattactgtgtgagagtttctggtggggatggagtcaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13897 JY8QFUQ01B5WCV No results 13898 JY8QFUQ01DANKY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13899 JY8QFUQ01COVBF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ5*01 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccaggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13900 JY8QFUQ01B8CTC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 108 53.33 72/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcagtttcagagactatgccatgagttgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13901 JY8QFUQ01BFKFB No results 13902 JY8QFUQ01AL5M7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13903 JY8QFUQ01ADX4H No results 13904 JY8QFUQ01AYXAJ unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13905 JY8QFUQ01COIIV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + gtctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13906 JY8QFUQ01DGP1W productive (see comment) Homsap IGHV3-11*01 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GGAGGGACT' (9 nucleotides at position 90 to 98 in the user submitted sequence), (do not cause frameshift); cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcaaacatcaatagtGGAGGGACTagtgggaggaccatatattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13907 JY8QFUQ01BA4OA productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 13908 JY8QFUQ01AXQRP No results 13909 JY8QFUQ01B4EWS unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13910 JY8QFUQ01CR219 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 815 85.78 187/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaaggggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13911 JY8QFUQ01BFG7N productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13912 JY8QFUQ01AUQ2H unknown (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 93.58 204/218 nt 9 7 X 9.7.X [1.17.38.X] null + No rearrangement found stop codons tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 13913 JY8QFUQ01BK8JB unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc 13914 JY8QFUQ01DCEQ6 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 3 8 10 X 8.10.X [2.17.38.11] CTTDGGISS#FDFW out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtGaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgctggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaagaacacgctgtatttgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtaccacagatgggggcatctcgtcccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13915 JY8QFUQ01DMHHL productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagccCcgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13916 JY8QFUQ01DGJ39 No results 13917 JY8QFUQ01BM7CU No results 13918 JY8QFUQ01DBLIP unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDY* in-frame + stop codons in FR3-IMGT at codon 74 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtgggctctgtgatggAgccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactgaggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 13919 JY8QFUQ01BTTDX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 933 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 80 to 82 in the user submitted sequence), (do not cause frameshift); agcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13920 JY8QFUQ01C6ZSG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13921 JY8QFUQ01BEO23 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13922 JY8QFUQ01DM9SV productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1011 97.2 208/214 nt 96.26 206/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [0.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); gggtttcagcttcaggagctctggcatgaactgggtccgccaggctccagggaaGggggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13923 JY8QFUQ01AIFVT No results 13924 JY8QFUQ01C4KPI unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 821 85.97 190/221 nt 85.52 189/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKGTRL*RLVYI#DSW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ggccgtctggattcattttagccaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagCcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaagggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13925 JY8QFUQ01DQU8I productive (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD6-6*01 F 1 8 8 21 8.8.21 [1.17.38.11] CAKDLGYSISSGASTHYYGMGVW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01DQU8I ; 7 AA in Homsap_IGHV3-69-1*01), and low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); cctctggattcgcttttggtgactatgccatgaactgggtccgccaggctccagggaaggggcCtggaatgggtctcatttgtcaccactactggcagttccacatattatgcagactccgtgaagggccgattcaccgtttccagagacgacgccaagaatctactgtatcttcagatgaccggcctgagagacggggacacggctacatattactgtgcgaaagacttggggtacagcatctcgtcgggggcctccacgcactactacggaatgggcgtctggggccaagggacaacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13926 JY8QFUQ01BRRCI productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13927 JY8QFUQ01AW9QR productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-22*01 F 2 10 7 21 10.7.21 [1.17.38.11] CARDVYDDGGYYGPYYYYGMAVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); tctccggtgAgccccatggccaataataatttctattggagctggattcggcagcccgccgggaaggGggctggagtggcttgggcgtgtgtatgtcagtgggaccaccaactacaaccccgccctcgagagtcgaatcaccatttcaatagatcggtccaagaaccagttctcgctgaacttgacctcagtgaccgccgctgacacggccatttattactgtgcgagggatgtttatgatgatggcggttattacggtccttattattactatggaatggccgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13928 JY8QFUQ01AGCW5 No results 13929 JY8QFUQ01A3A1C productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13930 JY8QFUQ01A9TVY unproductive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 13931 JY8QFUQ01BTRLU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13932 JY8QFUQ01DIY9J productive Homsap IGHV3-66*02 F 894 91.12 195/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccatcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgtggaact 13933 JY8QFUQ01DP6FF productive (see comment) Homsap IGHV3-11*01 F 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVDIRLGDWFFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtgaccactacatgagctggGgtccgccaggctccggggGAaggggtctggagtggatctcatacatcagtacaagtggtaatatggtttattacgcggactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcaaatgaacggcctcagagtcgaggacacggccgtctattactgtgtcgacataagactgggtgattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13934 JY8QFUQ01CMM9U unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLM#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttgatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccttgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 13935 JY8QFUQ01ASGP6 unproductive (see comment) Homsap IGHV3-48*03 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDLNWSFDS# out-of-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); cctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctgtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13936 JY8QFUQ01C7BM8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 438 85.12 103/121 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 X 2 22 X.2.22 [X.X.38.11] CVRDRLYDSSGYDFGELGDYSDHW in-frame + ctctggattcgccttcaactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagggccgaagacacggctgtatatttttgtgtgagagatcgtctctatgatagtagtggttatgactttggggaattgggggactattcagaccactggggccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13937 JY8QFUQ01B4I6V No results 13938 JY8QFUQ01AHAA1 productive Homsap IGHV3-48*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVGSMNIEASPPDDW in-frame - ctctggattcagcttcagttcctatagcatgagctgggtccgccaggctccggggaaggggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgaacagcctgagagccgaggacacggccgtctattactgtgcgaaagttggcagcatgaatatcgaggcgagccctcctgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacatggtcatcgcctgcctggtccagggcttcttccccca 13939 JY8QFUQ01BBTLX unproductive Homsap IGHV3-48*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.16.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccaggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13940 JY8QFUQ01A9C87 productive Homsap IGHV4-39*02 F 952 91.89 204/222 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.17.38.11] CARRYSWNYERFDPW in-frame - gtctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13941 JY8QFUQ01AOGS5 productive (see comment) Homsap IGHV1-8*01 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.16.38.11] CAREGLLGSLGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) aggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaaggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13942 JY8QFUQ01B7V6O unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 13943 JY8QFUQ01ANXAZ productive (see comment) Homsap IGHV1-3*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 71 of V-REGION: 'A' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagAttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 13944 JY8QFUQ01AVXVQ productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 1 8 8 12 8.8.12 [1.17.38.11] CGRPGRWDLSLDYW in-frame - cctctggattcatctttagtgactattacatgacctgggtccgccagagtccagggaaggggctggagtgggtggccaacataaaccaagatggaactgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaagtccctgtatctgcaaatgcacagcctgagaaccgacgacgcggctttatattactgtgggagaccagggagatgggatttatctcttgactattggggccagggaaccgtggtcaccgtctccttagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13945 JY8QFUQ01CJ5SE unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccgatcggtcttccccctggcgccctgctcccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13946 JY8QFUQ01DON2B No results 13947 JY8QFUQ01AKVLH productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13948 JY8QFUQ01AM13O No results 13949 JY8QFUQ01C4USB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13950 JY8QFUQ01CFG8N productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame + ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 13951 JY8QFUQ01BLE7A productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 285 82.35 70/85 nt 81.18 69/85 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcagagacaatgccaggaactccctctacttgcAaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca 13952 JY8QFUQ01CUDCX No results 13953 JY8QFUQ01DG6GC productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 13954 JY8QFUQ01BAPLA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 89.25 191/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKINNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); ctctggtgtctccatcagtagttcctactggagttggatccggcagCcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 13955 JY8QFUQ01CP3WA productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 13956 JY8QFUQ01AJ6F3 productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13957 JY8QFUQ01CNYIB productive (see comment) Homsap IGHV3-48*02 F (see comment) 743 82.11 179/218 nt 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaaggggActggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 13958 JY8QFUQ01A1MR0 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13959 JY8QFUQ01DTU0D unknown (see comment) Homsap IGHV4-4*07 F (see comment) 525 73.04 149/204 nt 72.55 148/204 nt 10 6 X 10.6.X [1.17.35.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01DTU0D ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (73,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggcctcatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13960 JY8QFUQ01CABRX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgaccggtgtcgtggaactcag 13961 JY8QFUQ01CNER9 unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGGFQ*TSGEG#YYNGLDVW out-of-frame + stop codons tggatacaccttcagcagttattatatacactgggtgcgacaggcccccggacaggggcttgagtggatggcaatgatcaacccaagtggtggtagtaccacgtacgcacagaagttccagggcagactcatcgtgaccagggacacgtccacgagtagtgtctacatggacctgagtagcctgagatctgaggacacgggcgtctatttctgtgcgagaggggggggcttccagtaaacgtcaggtgaagggactactacaacggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13962 JY8QFUQ01B5KT0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [0.17.38.11] CAKVVWSLWYFDLW in-frame - tacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13963 JY8QFUQ01CUMC5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1041 97.27 214/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13964 JY8QFUQ01A69S0 productive Homsap IGHV3-48*01 F 1075 99.54 215/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13965 JY8QFUQ01BA6HX unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CA*KKHYNSGTYLYNFDYW in-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); gtcctctggattcacctttagcGaactttgccatgacctgggtccgccaggctccagggagggggActggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggatagcctgagagccgaggacacggccgtatattactgtgcgtaaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 13966 JY8QFUQ01CCDCV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 13967 JY8QFUQ01DRROF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKASPKWEFLRTTFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttcgcagctatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtgctggtagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgacgacacggccatctacttctgtgcgaaggcgtcgccgaagtgggagtttctacgaaccacctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13968 JY8QFUQ01CVB6S unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARQYGSSSYVDF## out-of-frame - tctggatacatctttaccagctattggatcggctgggcgcgccagatgcccgggaaaggcctagagtggatggggatcatctatcctcctgactccgatacaagatacagaccggccttccaaggccaggtcaccatctcagtcgacaagtccaccagtaccgcctacctgcagtggagcagcctgaaggcctcggacagcgccatgtattactgtgcgagacaatatggttcgagcagttatgttgacttttggggccaggggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13969 JY8QFUQ01B4F5F No results 13970 JY8QFUQ01A92WW No results 13971 JY8QFUQ01AXELT unproductive Homsap IGHV3-7*01 F 991 94.98 208/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDPYNGGGYGAFDI## out-of-frame - gcctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13972 JY8QFUQ01CR0ZE unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13973 JY8QFUQ01AKWSG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13974 JY8QFUQ01AIRJC productive Homsap IGHV4-4*07 F 590 87.1 135/155 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 X 7 15 X.7.15 [X.6.38.11] CARQRGGGDRQWAFENW in-frame - gactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13975 JY8QFUQ01BSOV2 No results 13976 JY8QFUQ01B2ACS productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAVDCTSISCNGDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctgggttcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcggtagattgtactagtatcagctgcaacggagactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13977 JY8QFUQ01A7Z8B productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 956 92.76 205/221 nt 91.86 203/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 7 10 10 7.10.10 [1.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) tctggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaAaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13978 JY8QFUQ01BX22A No results 13979 JY8QFUQ01C5TP7 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1007 94.64 212/224 nt 94.2 211/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13980 JY8QFUQ01COIZ4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame + ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 13981 JY8QFUQ01C359E productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 6 10 9.6.10 [2.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaagGgggctggagtggattggacaaatccatcatgtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 13982 JY8QFUQ01BOZ0H productive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13983 JY8QFUQ01AM51E productive (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.16.38.11] CARAKLAGDGANWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gcctctggattcacccttagtagttattggatgaactgggtccgccagttccagggaaggggctgagtgggtggccaacatacaccaagatggaagtgagacatattatgtggactctgtgaagggccgattcaccgtctccagagacaacgcgaggaactcactgtatctgcagatgaacaacttgaaagtcgatgacgcggctgtgtattactgtgcgagagcgaagttagcaggagatggtgcaaactggtacttcgatctctggggccgtggcactctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13984 JY8QFUQ01BA6GM productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 13985 JY8QFUQ01A5HNY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgaccggtgtcgtggaactc 13986 JY8QFUQ01B6E5B productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13987 JY8QFUQ01BOQCN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13988 JY8QFUQ01BFRFT productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame - gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13989 JY8QFUQ01BJG2Y productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13990 JY8QFUQ01CP2YJ productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-25*01 F 1 8 8 10 8.8.10 [1.17.37.11] CTKLYRSYYEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift) cctctggattcagttttagtgactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaatatgaatcaagatggaagtgagaaaactatgtggactctgtgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatgtattattgtacgaaattgtatcggagctactacgaatactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 13991 JY8QFUQ01A9K2Q unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13992 JY8QFUQ01BN3QI productive (see comment) Homsap IGHV3-48*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggGggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtagaact 13993 JY8QFUQ01BT7V8 productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame + ctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatggaaacgtggtcatcgcctgcctggtccagggcttcttcccccca 13994 JY8QFUQ01BGFG8 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.16.38.11] CARGFSAWGQDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaagggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13995 JY8QFUQ01BPANL No results 13996 JY8QFUQ01AJRNU productive Homsap IGHV4-61*02 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARGYCSNAVCYQIMNW in-frame - tctctggtggctccatcagcagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13997 JY8QFUQ01DWTPQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 13998 JY8QFUQ01BLD8G productive Homsap IGHV3-48*02 F 986 94.95 207/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 13999 JY8QFUQ01A0O4F unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14000 JY8QFUQ01CKUI7 No results 14001 JY8QFUQ01BCFF4 No results 14002 JY8QFUQ01A1R7K productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 7 8 12 7.8.12 [0.17.38.11] CARGPVSGWYGDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tggatacatcttcaaaactactatatattctgggtgcgacgggcccctggacaagggcttgagtggatgggttgggtcaaccctaacagtggtgccacacactatgcaccgaaatatcagggccgggtcaccatgaccagggacacgtcattcgccacagcctacatggatttgagcatgttgacatctgacgacacggccatgtattactgtgcgagaggccctgtcagtggttggtatggtgacttctggggccagggaaccctagtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14003 JY8QFUQ01ATOJH unproductive Homsap IGHV3-9*01 F 820 86.3 189/219 nt 85.84 188/219 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CVKDRKSWWLQSVGC#FDIW out-of-frame - in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagAttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaaagctggtggctacaatctgttggatgcattttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14004 JY8QFUQ01BZKLC No results 14005 JY8QFUQ01DSG9D No results 14006 JY8QFUQ01AYDQ1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); aggctctgacttGcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14007 JY8QFUQ01C0A7I productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 14008 JY8QFUQ01A58UD productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14009 JY8QFUQ01AKWB3 No results 14010 JY8QFUQ01AKOZJ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 7 8 20 7.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) tttctggatacagtttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14011 JY8QFUQ01AYR9G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ6*02 F 157 72.58 45/62 nt Homsap IGHD1-14*01 ORF 2 8 8 16 8.8.16 [1.17.38.11] CARDRSVPQPKYYGMDVW in-frame + ctctggattcaccttcaataactataacatgaactgggtccgccaggctccagggaaggggctggagtggatctcatccattagtagtggtagtaatgacataaactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggtcggtgccgcaaccaaagtactacggtatggacgtctggggccaagggaccacggtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14012 JY8QFUQ01DQ6LN No results 14013 JY8QFUQ01DKQ19 No results 14014 JY8QFUQ01CIFL3 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14015 JY8QFUQ01CDVO9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 724 81.48 176/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 14016 JY8QFUQ01CC912 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14017 JY8QFUQ01BPUAJ No results 14018 JY8QFUQ01A09OY productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14019 JY8QFUQ01CAJM5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttactggatgcactgggtccgccAaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14020 JY8QFUQ01BB7QU No results 14021 JY8QFUQ01A666E productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - gcctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14022 JY8QFUQ01A19SQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 14023 JY8QFUQ01BTB07 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14024 JY8QFUQ01DI845 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame + cctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14025 JY8QFUQ01B3OBX productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 24 8.10.24 [1.17.38.11] CATDRPYYKKSLLADSGITTVWTFWG in-frame + Other possibilities: Homsap_IGHJ1*01 (shorter alignment but highest percentage of identity) ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14026 JY8QFUQ01BX3CP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14027 JY8QFUQ01CBYEJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14028 JY8QFUQ01AW6B3 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccgatcggtcttccccctggcgccctggctcccaggagcacctccgagagccacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14029 JY8QFUQ01B2NJT No results 14030 JY8QFUQ01C49WA No results 14031 JY8QFUQ01CR6ST productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14032 JY8QFUQ01DMXLR productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); aggcctctggattcaCcctttggttattatggcatggactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14033 JY8QFUQ01A0TAV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 14034 JY8QFUQ01CYKY8 productive (see comment) Homsap IGHV3-7*01 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); gacctctggaGttcacctttaGgtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14035 JY8QFUQ01APLYG No results 14036 JY8QFUQ01DJK44 productive Homsap IGHV1-18*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARGTQVRGVIKRPDYW in-frame - tggctacacgtttacctactatggtatcaactgggtgcgacaggcccctggacaaaggcttgagtggctgggatggattagcccttacaacggacacacaaactctgcacagagcctccagggcagagtcaacttgaccacagacagatccacgagcacggcctacatggagctgacgagcctgatatctgacgacacggccgtgtattactgtgcgagaggaacgcaggttcggggtgtgatcaagagacctgactactggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctcggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14037 JY8QFUQ01CGCMM No results 14038 JY8QFUQ01A9W4E productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-1*01 F 2 10 7 8 10.7.8 [1.17.38.11] CATVDRLTYW in-frame + tctctggtgtctccatgagcagtcttacttactactggggctggattcgccagccccccgggaagggcctggagtggattgggactctcttttatagtgggagcacctactacaatccgtccctcaggagtcgagtcaccatatccgctgactcgtccaagaaccagttctccctgaacctaaggtctgtgaccgccgcagacacggctgtctatttctgtgcgacggtggatcgactgacctactggggccggggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14039 JY8QFUQ01BKJ53 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 14040 JY8QFUQ01C4LWE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14041 JY8QFUQ01DAYCB productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 94 of V-REGION: 'C' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcCctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14042 JY8QFUQ01BJMYD productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 580 73.33 165/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*01 F 2 10 9 13 10.9.13 [1.17.38.11] CTRGSLTGTYPSDHW in-frame + Low V-REGION identity (73,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcggagacgatatatctggagacagtgttacttggaactggatcaggcagtccccagggagggggcttgagtggctcgggcgtatctttcacaggtctgagtggcataccgactacttggcgtctgttagaggccgaatctccatggatgtcgacacgtccaagaaccacttcaccctgcagctccgctctctgactcccgacgacacggctacatatttctgtacaagaggctctctaactgggacatatccttctgaccactggggtctggggaccccagtgaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14043 JY8QFUQ01CTQ0O unproductive Homsap IGHV4-4*07 F 872 89.77 193/215 nt 88.84 191/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-24*01 ORF 3 9 7 X 9.7.X [1.17.38.11] CARDFWRFLQFSG#YW out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'ATT' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgATTctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattTacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14044 JY8QFUQ01DF324 productive (see comment) Homsap IGHV4-61*02 F 844 86.94 193/222 nt 86.49 192/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 15 10.7.15 [2.17.38.11] CAREGDGYIYKRSFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gtctctggtggctccgtcagtagtggttcttactactggagctggacccggcagcccgccgggCaagggactggagtggattgggcgtgtccacagcggtggcagttccgactacaacccgtccctcacgggtcgagccaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgagtattactgtgcgagagagggggatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14045 JY8QFUQ01COK70 productive Homsap IGHV3-48*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 8 8.8.8 [1.17.38.11] CARDVPYRNW in-frame + ctctggattcagcttcagtacctatagcatgaactgggtccgccagactccagggaaggggctggagtgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctatttattactgtgcgagagatgtcccttatcgcaactggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14046 JY8QFUQ01ANH7Z productive (see comment) Homsap IGHV3-48*04 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaagggactggagtggggttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14047 JY8QFUQ01A9DBC productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 14048 JY8QFUQ01CH409 productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 14049 JY8QFUQ01ATS4G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14050 JY8QFUQ01BU3FD unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 487 83.94 115/137 nt 83.21 114/137 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca 14051 JY8QFUQ01C05E8 unknown (see comment) Homsap IGHV3-23*02 F, or Homsap IGHV3-23*03 F (see comment) 222 65.0 78/120 nt 63.33 76/120 nt 7 8 X 7.8.X [1.16.6.X] null + No rearrangement found Low V-REGION identity (65,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctggatacagtttaacagttatgccatgacttgggtccgccaggctccagggaagggctggagtgggtcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 14052 JY8QFUQ01DJHPR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*02 F 3 8 8 23 8.8.23 [1.17.38.11] CARDRRVFFGQLITTKIYHYGMDVW in-frame - cctctggattcaacttcaattattatagcatgagttgggtccgccaggctccgggaaagggactggagtgggtttcatacattagtactagtagtagttacatgtattacacggactccgtgaagggccgcttcaccgtctccagagacaacgccaagaaatctctgtatctggaaatgaacagcctaagggacgaggacacggctgtctacttttgtgcgagagatcgacgagtgttctttggacaattaataaccaccaaaatctaccactacggcatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14053 JY8QFUQ01CC9HI productive Homsap IGHV3-9*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame - cctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14054 JY8QFUQ01BS7HV unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 86 57.53 42/73 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found cctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14055 JY8QFUQ01BUOD5 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 883 89.5 196/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDLRGSTMASD#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccgactgtcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaaggggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 14056 JY8QFUQ01AHQCJ No results 14057 JY8QFUQ01DU8GL No results 14058 JY8QFUQ01ATDFY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14059 JY8QFUQ01DR144 unproductive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPFTVTTGKDAY## out-of-frame + tctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14060 JY8QFUQ01B9CJF productive (see comment) Homsap IGHV1-2*02 F 808 86.85 185/213 nt 86.38 184/213 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD3-16*02 F 2 8 7 15 8.7.15 [0.17.38.11] CARHFCDTNDVCDFDIW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) tggatacagcttcaccgacttttacattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaatggtggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggagatgagcaggctgagatctgacgacacggccatttattactgtgcgagacatttttgtgacaccaacgacgtctgtgattttgatatctggggccaggggacaaaggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 14061 JY8QFUQ01CZTSW No results 14062 JY8QFUQ01BI2BQ No results 14063 JY8QFUQ01AKY7R No results 14064 JY8QFUQ01C6USK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14065 JY8QFUQ01B7J8X No results 14066 JY8QFUQ01DDCM9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 879 89.09 196/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [2.17.38.11] CVREGAATGSFYYW in-frame - aacctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14067 JY8QFUQ01CQE5A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 8 13 8.8.13 [1.17.38.11] CVRGVRDGTGIIDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ccatggattcctcttcagtggccactggatgcactgggtccgccaagctccagacaaggggctggcgtgggtctcaCgtcttaaccccggacgggagttttacgaactatccggactccatgaggggccgattcgccatctccagagacaacgccaagaacacagtgtatctgcaaattaacaatctgagacccgatgacacggccgtctattactgcgtaagaggcgtaagagacggaactggaatcatcgactactggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14068 JY8QFUQ01CD3K8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 797 85.32 186/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagtcgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14069 JY8QFUQ01BS1BC No results 14070 JY8QFUQ01BM6SP unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F (see comment) 764 84.19 181/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 111 68.63 35/51 nt 8 7 X 8.7.X [1.17.38.11] CASVRPRRTVLRL (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctcgctcacgggtttcaagtggggctggatccggcagcccccaggggagggactgcaatggattggacatatctctttcgttggggacaccagttatgacccttccctcaggagtcgagtcaccatttcagtcgacacgtccaagaaccagttctccctgaaactgaactctatgactcctgcggacacggccgtctattactgtgcgagcgtgcgtcctcggagaacggttcttcgacttctgggcctggaaccctggtcaacgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg 14071 JY8QFUQ01CXQ06 No results 14072 JY8QFUQ01BXEW2 No results 14073 JY8QFUQ01DMU46 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 568 73.06 160/219 nt 72.6 159/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (73,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctagattcaTcgtttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14074 JY8QFUQ01CRNW3 productive Homsap IGHV3-11*01 F 855 88.48 192/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDGDADYGDLPIPFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattcagtttcactgaccaccacatgagctggatccgccgggctccagggaaggggctggagtgggtgtcatacattagtcctacaggtagtgccatattttacgcagactctgtgaaggcccgtttcaccatctctagggacaacgccaagaatttactatatctacaaatgaacagcctgagacccgaggacacggccatctattactgtgcgagagatggggacgcggactacggtgacttgcccatccctttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14075 JY8QFUQ01AOHFB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14076 JY8QFUQ01C1CU1 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14077 JY8QFUQ01ARFJE unknown (see comment) Homsap IGHV3-11*01 F (see comment) 707 80.28 175/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagcgacaactacatgagctggatccgccaggctccagggaaggggctggattgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcacttttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14078 JY8QFUQ01C6PCV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14079 JY8QFUQ01CH9ZV No results 14080 JY8QFUQ01CI1BM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14081 JY8QFUQ01A607Q unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [0.17.38.11] CARDLIAAADNGGFG#NWFDPW out-of-frame - in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tggatataccttcagcaattactatatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtggcacaaAactacgcacggaagtttcaggacagagtcaccatgaccagggacacgtccacgaacacagtgtatatggagctgagcagcctcagatctgaggacacggccgtatattactgtgctcgagatcttatagcagcagctgataatggggggtttggggaactggttcgacccctggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14082 JY8QFUQ01C3WLI productive (see comment) Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14083 JY8QFUQ01CF1C3 No results 14084 JY8QFUQ01DERB1 No results 14085 JY8QFUQ01AOJ8L productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14086 JY8QFUQ01DVOAK productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtAgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14087 JY8QFUQ01DKG5C unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14088 JY8QFUQ01A3ZFE productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14089 JY8QFUQ01B91TW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 7 8 15 7.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14090 JY8QFUQ01BYSF3 productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14091 JY8QFUQ01A4TFA productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14092 JY8QFUQ01COGK9 No results 14093 JY8QFUQ01CU3ZW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagccgtccaccgaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14094 JY8QFUQ01CLSK8 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 14095 JY8QFUQ01AUA9M No results 14096 JY8QFUQ01BKXS7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14097 JY8QFUQ01B8XQA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANACPPYNWN#YFYYYGMDVW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctggattcaTcgttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctgccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14098 JY8QFUQ01DA9FW productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) cttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14099 JY8QFUQ01AESJH productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 849 88.79 190/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame - ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggctgtatattactgtgccagagatgagctcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14100 JY8QFUQ01A086G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - tctctggatttaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14101 JY8QFUQ01BLH3L unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14102 JY8QFUQ01AD8K3 No results 14103 JY8QFUQ01BGG1W unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttaagtga 14104 JY8QFUQ01ATP3O No results 14105 JY8QFUQ01B8RHG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14106 JY8QFUQ01AIJVY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctggatctccttcagcaattatgccatccactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14107 JY8QFUQ01CDH08 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - gcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14108 JY8QFUQ01AGKHP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14109 JY8QFUQ01BK7AV productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14110 JY8QFUQ01BAIFQ No results 14111 JY8QFUQ01CCRU2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14112 JY8QFUQ01CC9NQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14113 JY8QFUQ01A32YE productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14114 JY8QFUQ01B5ZU7 unproductive (see comment) Homsap IGHV4-61*08 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggtgcctccatcagcagtagtggtcactactggagttggatccggcagcccccagggaagggactggaattcattggaaaaaCtctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatttcagtggacacgtccgagaaccagttctccctgagcctgaggtctgtgaccgctgcggacacggccctttattactgtacgagggggggtatacacttatgacagcccgtggggccaggggcattcaggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14115 JY8QFUQ01C90EK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14116 JY8QFUQ01B8SJV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14117 JY8QFUQ01B4CAM productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctacattcgcctttagcaactatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14118 JY8QFUQ01CM9Y8 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt 77.52 169/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [2.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtgtctggtggctccatcgccacttatcattggtggaattgggtccgccagaccccgggaagggactggagtggattggagaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14119 JY8QFUQ01BWGPB unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSRHSASGSYSDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactgggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14120 JY8QFUQ01DAM5H No results 14121 JY8QFUQ01AYDLJ No results 14122 JY8QFUQ01ADU0D unproductive Homsap IGHV4-61*02 F 965 93.21 206/221 nt 92.76 205/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 10 7 X 10.7.X [2.17.37.11] CATVARR#AFDIW out-of-frame - in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 196 in the user submitted sequence), (cause frameshift) tcgtctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaccccgcagacacggccgtttattactgtgcgacagtggcgcgccgggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14123 JY8QFUQ01BEJAX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctgatttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 14124 JY8QFUQ01CCM83 productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcag 14125 JY8QFUQ01AS9Y7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + tctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14126 JY8QFUQ01CNN46 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14127 JY8QFUQ01BLZ8K No results 14128 JY8QFUQ01DRPB2 No results 14129 JY8QFUQ01C3F1P productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 952 94.37 201/213 nt 93.9 200/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [0.16.38.11] CARDGGHSYGPSFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacaccttcaccaggtacattatgcactgggtgcgacaggccctggacaagggcttgagtggatgggaataatcaaccctagaggtgttagcagaagctacgcacagaagttccagggcagagtcaccatgaccaccgacacgtccacgagcacagtctatatggagctaaacagcctgagatctgaggacacggccgtttattactgtgcgagagatggagggcacagctatggaccctcctttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 14130 JY8QFUQ01DH40M productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 14131 JY8QFUQ01CSF7P unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 65.84 133/202 nt 8 8 X 8.8.X [1.17.32.X] null + No rearrangement found Low V-REGION identity (65,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14132 JY8QFUQ01C248S No results 14133 JY8QFUQ01B2EP4 productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARAGYYYGSGSYFEW in-frame + tctctggtgactccatcagcagtggcagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtttctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagctttccctgaagctgacgtccgtgaccgccgcagatacggccgtgtattattgtgccagagcgggttattattatgggtcggggagttacttcgagtggggccagggaaccctgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14134 JY8QFUQ01BWC6T productive Homsap IGHV3-21*04 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14135 JY8QFUQ01B5R9J No results 14136 JY8QFUQ01A2FHS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARSRTFYGSANYW in-frame - gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14137 JY8QFUQ01AYNJ8 No results 14138 JY8QFUQ01CPQSF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 14139 JY8QFUQ01C2YDS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagAccctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14140 JY8QFUQ01A3IIQ productive (see comment) Homsap IGHV3-7*01 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSDFYSTGHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ggctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14141 JY8QFUQ01BIGJ3 No results 14142 JY8QFUQ01AQDEK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14143 JY8QFUQ01BKNRL unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 157 54.19 97/179 nt 8 7 X 8.7.X [1.17.26.X] null + No rearrangement found cctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14144 JY8QFUQ01C73TY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 956 92.76 205/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggcgccatcagcagtaatagttactactgggactggatccgccagcccccagggaaggggctggagtggattgggagtatgttttatactggggtcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14145 JY8QFUQ01A5DBU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctcctccaggagcacctccgagagcacagcggccctgggctgcctgtcaaggactacttccccgaacggtgacggtgtcgtggaactca 14146 JY8QFUQ01BQ9NT No results 14147 JY8QFUQ01DTUZL No results 14148 JY8QFUQ01DS1AX productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 14149 JY8QFUQ01CYGW1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14150 JY8QFUQ01B254T No results 14151 JY8QFUQ01COOTQ productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14152 JY8QFUQ01DM8TO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcagcctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 14153 JY8QFUQ01A5EZX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKRLQAVADDAFDF## out-of-frame + cctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggcccaagggacaatggtcaccgtctcctcagatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14154 JY8QFUQ01AU2BA productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14155 JY8QFUQ01DHKLW unproductive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CAKLADTGEWSNRIFSF#W out-of-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttcatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14156 JY8QFUQ01CM07M productive Homsap IGHV4-34*08 F (see comment) 733 82.41 178/216 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-9*01 F 1 8 7 14 8.7.14 [2.17.38.11] CAKSRIGWFNDAFDVW in-frame - Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtggattggggaaatcaatcacagtggagacaccaattacaacccgtccctcaggagtcgagtcatcatttcaatagacacgtccaagagcgaattctccctgaagatacactctgtgaccgccgcggacacggctatatattactgtgcgaaaagtcgaattggctggttcaatgatgcatttgatgtctggggccaagggacaagggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14157 JY8QFUQ01AUI3L productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14158 JY8QFUQ01COOH3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [0.17.38.11] CVKDISRSGCFEYW in-frame - tggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14159 JY8QFUQ01BCNRJ No results 14160 JY8QFUQ01CJEU1 unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGAPIL** (see Functionality comment) out-of-frame - stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14161 JY8QFUQ01AXRQG unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 644 93.84 137/146 nt 93.15 136/146 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-16*01 F 2 8 X X 8.X.X [1.8.31.11] CARRDVGLHAFDL## out-of-frame + in FR2-IMGT, from codon 47 of V-REGION: 72 nucleotides (from position 54 in the user submitted sequence), (do not cause frameshift) gttctggatccaattttaactacgactggatcggctgggtgcgccagatgcccggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggtacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 14162 JY8QFUQ01DFIIV productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14163 JY8QFUQ01CMXUR unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaAaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggcaggcgaggcaacctggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacatggtcgtcgcatgcctggtccagggcttcttccccca 14164 JY8QFUQ01CE504 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 14165 JY8QFUQ01BY2NW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 14166 JY8QFUQ01DCGS5 productive (see comment) Homsap IGHV3-7*01 F (see comment) 688 80.09 173/216 nt 79.17 171/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 7 8 15 7.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcatggatgagttGgggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14167 JY8QFUQ01CFG7V No results 14168 JY8QFUQ01DVGZS unproductive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVIPGRGKLC#FDVW out-of-frame + ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggcaaactatgctttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14169 JY8QFUQ01DUMXO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14170 JY8QFUQ01A50XT productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccagGgggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14171 JY8QFUQ01AVHVI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14172 JY8QFUQ01BSI3K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcagccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14173 JY8QFUQ01AX7IZ productive (see comment) Homsap IGHV4-61*02 F 1023 96.36 212/220 nt 95.91 211/220 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD5-18*01 F 3 10 7 18 10.7.18 [1.17.37.11] CARGSFRDGGHGYGPWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtggaagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatttatatcagtgggggcaccgactacaaccctccctcaagagtcgagtcaccatatcggcagacacgtccaagaaccagttctccctgaagctgatctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggttctttcagagacggtggacacggctatggcccctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14174 JY8QFUQ01DUQ3Y productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 926 90.62 203/224 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame - cctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14175 JY8QFUQ01AFVNN No results 14176 JY8QFUQ01CNXZ5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14177 JY8QFUQ01ADZFS productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 14178 JY8QFUQ01CVY8N productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARISAFDQW in-frame + tacacggcgggtccttcaaaggttactattggagctggatccgccagcccccaggaaaggggctggagtggattggagaaatcgaccatagtggaaacaccaactacaacccgtccctcaagagtcgagtcaccgtgacagttgacacatccaagaaccaaatttccctgaatttgacctctgtgaccgccgcggacacggctatttattactgtgcgcgtatttcagcctttgaccagtggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 14179 JY8QFUQ01A0MXA unproductive Homsap IGHV3-11*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRLLSSGWPPHDG#SW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgactactacatgtcgtggatccgccaggctccaggaaAaggggctggagtgggtctcatacattagtagtagtggtaattccatatactacgcagactctgtgaggggccgattcaccacctccagggacaacgccaagaattcgatatatctacaaatgaacagcctgagagccgacgacacggccgtttatttttgtgcgagaagacttctgagcagtggctggccaccccacgatggggctcctggggccagggaacccacgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14180 JY8QFUQ01CR1U3 productive (see comment) Homsap IGHV1-3*01 F 849 88.79 190/214 nt 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacagcttcactaatcacattatccattgggtgcgccaggCcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14181 JY8QFUQ01CXEZ8 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 965 92.79 206/222 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD1-26*01 F 3 8 10 21 8.10.21 [1.17.38.11] CTRDATDNGRYYLGSGYFGMDVW in-frame - tctggattcatctttggtgattacgcnatgcactggttccgccaggctccagggaaggggctggaatgggtaggtttcattagaagtacagcttatggtcagacaacacaatacgccgcgtctgtgagaggcagattcaccatctcaagagatgattccaaaagcagcacctatctgcaaatgaatagcctgaaaagcgaggacacagccgtgtattactgtaccagagacgccacagataatgggagatactacctcggctcgggatatttcggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14182 JY8QFUQ01CECLX productive (see comment) Homsap IGHV1-2*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARDGISMTLVRGVRPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); tggatacaccttcatcggccattaCtatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14183 JY8QFUQ01BI87O productive Homsap IGHV4-61*02 F 848 87.33 193/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame + tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccacagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcatcgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14184 JY8QFUQ01ASNEE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14185 JY8QFUQ01C0VRM productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14186 JY8QFUQ01AGYJ3 No results 14187 JY8QFUQ01CHYBT unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDSGPSGYARYESMDV## out-of-frame + in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaggggcgtggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaGggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctgggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactattccccgaaccggtgacggtgtcgtggaactcag 14188 JY8QFUQ01AKHHA No results 14189 JY8QFUQ01BBC42 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.16.37.11] CVSDLAGQKGF# out-of-frame + in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14190 JY8QFUQ01BANLS productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 804 86.45 185/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWGADAFDIW in-frame + ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14191 JY8QFUQ01DM3BO productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 14192 JY8QFUQ01AFV6Z No results 14193 JY8QFUQ01B8AYU unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*03 F 3 8 8 X 8.8.X [1.17.38.11] CVRSPPSYIWRW*DG#FDHW out-of-frame + stop codons Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggtcgttgtttagcaactatgccatgagttgggtccgccaggctccagggaaggggctggagtgcgtcgcagctatcagtggtaatggtgctgacacaaggtacgcagactccgtgaagggccgactcaccatctccagggacaacgtcaataagagggtgtatttggaaatgaagagcctgagagtcgaggacacggccacatattattgtgttagatcccccccgtcttatatatggagatggtaggacggacttttgaccactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14194 JY8QFUQ01AFNVU No results 14195 JY8QFUQ01AJGW3 No results 14196 JY8QFUQ01DEWDW productive (see comment) Homsap IGHV4-61*02 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARCPNYNIGTPGGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaaggGgaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggaccccggggggctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14197 JY8QFUQ01CGTDW productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1053 96.46 218/226 nt 96.02 217/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctttttcccc 14198 JY8QFUQ01BVB0R productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14199 JY8QFUQ01CXUDL productive Homsap IGHV3-21*04 F 873 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAKGYHGPFDSW in-frame - ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactacgcagactctgtggagggccgattcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14200 JY8QFUQ01AXKB6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14201 JY8QFUQ01CLU61 productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14202 JY8QFUQ01A53BA productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14203 JY8QFUQ01DLU5K productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14204 JY8QFUQ01B3LHZ productive Homsap IGHV4-39*03 F 915 90.87 199/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + ctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacagccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14205 JY8QFUQ01BN8CT No results 14206 JY8QFUQ01BMPYC productive Homsap IGHV3-74*03 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + ctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14207 JY8QFUQ01DWRQL No results 14208 JY8QFUQ01AYL0X productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 807 93.48 172/184 nt 92.93 171/184 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.6.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 33 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtagttactggatgcactgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14209 JY8QFUQ01CRML5 productive Homsap IGHV3-9*01 F (see comment) 749 83.96 178/212 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 7 8 16 7.8.16 [X.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (83,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14210 JY8QFUQ01BFJMN productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 91.28 199/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'A' (1 nucleotides at position 139 to 139 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccAatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaGggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14211 JY8QFUQ01CDNWM unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.37.11] CTTGGWN*L##W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacaggggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14212 JY8QFUQ01BBSWK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14213 JY8QFUQ01AOGGT productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - cctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14214 JY8QFUQ01AYGBK No results 14215 JY8QFUQ01BPUXF No results 14216 JY8QFUQ01CNGMT unproductive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F or Homsap IGHV3-33*03 F 1035 97.7 212/217 nt Homsap IGHJ3*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD4-11*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAGPVTTNYYYYV#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gtctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcatttatacggtatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcggggcccgtaactacgaactactactactacgtgatgacgtctggggccaagggaccacggtcaccgtctcctcagggagtgcatccgccccaaccc 14217 JY8QFUQ01BJIED productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14218 JY8QFUQ01DFG5Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagAcccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14219 JY8QFUQ01BNGAT productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1034 95.98 215/224 nt 95.54 214/224 nt Homsap IGHJ6*02 F 230 90.91 50/55 nt Homsap IGHD3-16*01 F 1 8 10 10 8.10.10 [1.17.38.11] CITDLVYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcacttttaataacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaAaaaccgaaactgatggttggacagcagaccacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaagaacacgctgtatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattattgtatcacagatttggtctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 14220 JY8QFUQ01AJ6J6 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 782 83.48 187/224 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTWDSTGYFRLTW in-frame - Low V-REGION identity (83,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaagggctggagtggggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14221 JY8QFUQ01AX3Y3 unknown (see comment) Homsap IGHV3-7*01 F 1026 96.77 210/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 14222 JY8QFUQ01C5CP6 productive (see comment) Homsap IGHV3-7*02 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaagGggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14223 JY8QFUQ01DC98A No results 14224 JY8QFUQ01BXTDZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARGVGQQLPPLDW in-frame - gtctctcgtgcctccatcaatatttcctactggagctggatccggcagcccccagggaggggactggagtggattggatatatctatgatagtgggagtaccaactacaacccctccctcaagagtcgagtcaccatatctatagacacgtccaagaaccagttctccctgaggctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14225 JY8QFUQ01B89S0 productive (see comment) Homsap IGHV3-72*01 F 958 92.0 207/225 nt 91.56 206/225 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [2.17.38.11] CARLHYSGGWYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaAaggggctggagtgggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagataactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14226 JY8QFUQ01AT1SV productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDMGSGRYFEPYDYW in-frame - gggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14227 JY8QFUQ01A5NXH unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 791 85.58 184/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttaTacttaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14228 JY8QFUQ01C7UHC productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARDMGSGRYFEPYDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattcaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14229 JY8QFUQ01AZ6JH unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 580 74.07 160/216 nt 73.61 159/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (74,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaAaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14230 JY8QFUQ01A2XE0 unproductive Homsap IGHV3-48*01 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaaggggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14231 JY8QFUQ01DFZ5Q productive (see comment) Homsap IGHV3-48*01 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.16.38.11] CAKDRITIFSYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccaggagggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14232 JY8QFUQ01AQJEX No results 14233 JY8QFUQ01AGZ4S unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 84 51.52 68/132 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons tctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14234 JY8QFUQ01AUNK1 productive (see comment) Homsap IGHV1-24*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14235 JY8QFUQ01DE82D unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 549 76.72 145/189 nt 8 8 X 8.8.X [1.17.28.X] null - No rearrangement found Low V-REGION identity (76,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttgatgattttgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaggatagtctatgcggactctgtgaagggccgattcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14236 JY8QFUQ01BH0D4 No results 14237 JY8QFUQ01BWBZS productive (see comment) Homsap IGHV3-72*01 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.16.38.11] CARLHYSGGWYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagatgactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14238 JY8QFUQ01AB75W productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.49 182/218 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDIWAREWNDMAAFQMW in-frame + Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cccccggaatcatttttcccagctatgtcatgagttgggtccgccaggccccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14239 JY8QFUQ01DJOGY No results 14240 JY8QFUQ01AT8HH productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 3 10 7 11 10.7.11 [1.17.38.11] CAGGEDPFKVRHW in-frame + tctctggtggctccttttctaatcatggttaccactgtagttggctccgccagttcccagggaaggacctggagtggattgcctacatctattacactgggagcaccgagtataacccgtccctcaggagtcgagttgccatatcagtggacacgtctgggaaccagtgttccctggagttgaactctgtgagtgccgcggacacggccgtctattactgtgcgggaggcgaggatcccttcaaagttcgacactggggccagggaacccgggtcaccgtctcctcagcatccccggaccagccccaagggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 14241 JY8QFUQ01CPS2S unproductive Homsap IGHV4-61*02 F 894 89.24 199/223 nt 88.34 197/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [2.17.37.11] CAREFWRFLQFSG#YW out-of-frame - in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) ctgtctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattAgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagaattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14242 JY8QFUQ01CQ7EP productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 869 86.78 197/227 nt 85.46 194/227 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 10 12 8.10.12 [2.17.38.11] CSYFRHEPYHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tagacgctggattcgcctctggtgattatgctatgaGgttggttccgccaggctccgggaaaAGggggctggagtgggtggGggttcatcagaagcagagcttacactgggacaccagaatacgccgcgtctgtgaaaggcagattcaccatctccagagatgcttccaaaagtattggctatctgcaaatgaacaatctgaggatcgaggacacagccgtctattattgctcttattttcggcatgagccatatcactttgactattggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14243 JY8QFUQ01CC78V productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14244 JY8QFUQ01AX9R5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14245 JY8QFUQ01B6BDJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKKHYNSGTYLYNFDYW in-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 14246 JY8QFUQ01C3T6M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 912 92.06 197/214 nt 91.59 196/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARRDVGSHAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tggatacaattttaactacgactggatcggctgggtgcgccagatgcCccgggaaaggcctggagtggatggggatggtctatgttggtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14247 JY8QFUQ01BQGVY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame - ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14248 JY8QFUQ01DMS85 No results 14249 JY8QFUQ01BOY6X productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 14250 JY8QFUQ01B2FBT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14251 JY8QFUQ01B325I productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 767 83.26 184/221 nt 82.81 183/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRWSGTYPFASW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagTccccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggctttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtggaactcag 14252 JY8QFUQ01BYCK4 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 448 70.1 136/194 nt 8 7 X 8.7.X [1.17.31.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BYCK4 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (70,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14253 JY8QFUQ01A3R6Q productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1049 96.04 218/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + ctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 14254 JY8QFUQ01AM7BU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14255 JY8QFUQ01CG6Q8 No results 14256 JY8QFUQ01C55F1 unknown (see comment) Homsap IGHV3-74*03 F 117 54.07 73/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14257 JY8QFUQ01C92G5 productive Homsap IGHV3-33*04 F (see comment) 703 80.37 176/219 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [2.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcatttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14258 JY8QFUQ01DTK17 unproductive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt 98.22 221/225 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [2.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcCaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14259 JY8QFUQ01CJDYI productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 100.0 190/190 nt 99.47 189/190 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.7.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 28 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 14260 JY8QFUQ01DQ3JG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14261 JY8QFUQ01AWWKU productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ttctggaGtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14262 JY8QFUQ01CZ24N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14263 JY8QFUQ01DMBXT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLGLNAVYAFDV## out-of-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctgggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14264 JY8QFUQ01CWSL1 No results 14265 JY8QFUQ01A2FU8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 86.13 205/238 nt 85.71 204/238 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [7.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 26 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); gagactctcctgcactgtcCtttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14266 JY8QFUQ01CZIOF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'A' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatcAtccagagacaacagcaaaaactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14267 JY8QFUQ01CRG3F No results 14268 JY8QFUQ01DTOZ0 productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctacattcacgGtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14269 JY8QFUQ01DSXI7 unknown (see comment) Homsap IGHV1-2*03 F 83 57.35 39/68 nt 55.88 38/68 nt 8 X X 8.X.X [0.13.X.X] null - No rearrangement found in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) tggatacaccttcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14270 JY8QFUQ01DDKKR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 14271 JY8QFUQ01AXH8G productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD7-27*01 F 2 8 7 7 8.7.7 [1.17.38.11] CARSQGDYW in-frame + tctctggtggctccatcagtccctacccctggagctggatccggcagtccccagcgaagggactggagtggattggctttatcttttacaatgggaccaccatctacaacccctccctccagagtcgactcaccatttcaatagacacatccaagaaccagttctccctgaaattggcctctgtgactgctgcggacacggccatatattattgtgcgagatcacagggggactactggggccggggagcccgggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 14272 JY8QFUQ01DFHF6 unproductive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGE##DYW out-of-frame - stop codons tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagacttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14273 JY8QFUQ01BZURD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDS## out-of-frame + gtctggatttacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctggggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14274 JY8QFUQ01DQZS4 No results 14275 JY8QFUQ01DPBOX productive (see comment) Homsap IGHV4-4*07 F (see comment) 683 80.0 172/215 nt 79.53 171/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARECTNEAGGPRHLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); tctctggtgGgccccatcaatagtagtgactactattggacttggatccggcagcccgccgggaggggactggaatgggtcgggcgtgtcttcatgaatggccttaccgactacaatccatccttcggcagccgtctcaccatgtccattgacatgtcgaagaaccaattctccctgaagttgacctctgtgaccggcgctgacacggccctttattactgtgcgagagaatgtactaatgaggctggcggaccgagacacctggactcctggggccacggaactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14276 JY8QFUQ01BURVQ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 14277 JY8QFUQ01BHF2R productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt 14278 JY8QFUQ01DURLP unproductive Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-12*01 F 2 7 8 X 7.8.X [1.17.38.11] CARDQVTEDY## out-of-frame - in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14279 JY8QFUQ01BJ5LY unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 850 88.43 191/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD3-10*02 F 2 8 7 X 8.7.X [2.17.38.11] CAREFPGAFFGQ#YGMDVW out-of-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcgggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttccgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14280 JY8QFUQ01C60GD productive (see comment) Homsap IGHV3-7*01 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [2.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) gtctctggattcaccttagtagggtttggatgacctgggtccgccaggGgtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14281 JY8QFUQ01BNT82 No results 14282 JY8QFUQ01A0D5E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 808 86.85 185/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 7 8 12 7.8.12 [0.17.38.11] CVKDISRSGCFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 8 in the user submitted sequence), (cause frameshift) tggattccagttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14283 JY8QFUQ01A7RNH No results 14284 JY8QFUQ01DJIV3 productive (see comment) Homsap IGHV3-7*01 F 853 87.0 194/223 nt 86.55 193/223 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [3.17.38.11] CGRDERGADLPNDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); tgcagcctntggattcaccgttagtaggtattggatgagctgggtccGgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14285 JY8QFUQ01DM280 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + cctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14286 JY8QFUQ01BAR43 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 841 87.96 190/216 nt 87.04 188/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.16.38.11] CAKGDSPIASRLYIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ttctggattcacctttggtgattatgctatgagctgggtccgccaggctccagggaagggccggagtgggtctcagCcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14287 JY8QFUQ01BMLD6 No results 14288 JY8QFUQ01ANG2X productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14289 JY8QFUQ01AVLL5 No results 14290 JY8QFUQ01DK39Y unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 482 83.82 114/136 nt 82.35 112/136 nt 8 8 X 8.8.X [1.16.12.X] null + No rearrangement found Low V-REGION identity (83,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) tctggattcacctttaacagccatgccatgagttggtccgccaggctccagggaggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactca 14291 JY8QFUQ01CQ8ID No results 14292 JY8QFUQ01AXFNY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14293 JY8QFUQ01AVUNN No results 14294 JY8QFUQ01C0DFI productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14295 JY8QFUQ01C5MDA No results 14296 JY8QFUQ01B18V1 No results 14297 JY8QFUQ01AXWMP productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctttggtggctccatcagcCaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14298 JY8QFUQ01BODTQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14299 JY8QFUQ01BV9UK productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14300 JY8QFUQ01AUOAK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca 14301 JY8QFUQ01C00CS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14302 JY8QFUQ01A0Z8X No results 14303 JY8QFUQ01BXQJQ productive (see comment) Homsap IGHV3-7*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14304 JY8QFUQ01A5GJS No results 14305 JY8QFUQ01CI7FA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcactctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14306 JY8QFUQ01A9YC6 productive Homsap IGHV3-7*01 F 1045 97.72 214/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - gcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14307 JY8QFUQ01AGZYH No results 14308 JY8QFUQ01CPDZW productive Homsap IGHV4-61*02 F (see comment) 695 79.64 176/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERDRSIGGAADLDSW in-frame - Low V-REGION identity (79,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccagtgtacccgtcagtcgtggaggttactactggaattggatccggcagcccgccgggaaggggctggagtggattggacgtgttgacagtaatggattcgtcaggtacaattcctccctcaaaagtcgactatctatgtcactaaacacgtccaagaatcagatctccctgatactgaggtctgtgatcgccgcagacacggccgtgtatttctgtgcgagggaacgtgataggtcgattggcggagcggcagatcttgactcctggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14309 JY8QFUQ01DRFCG No results 14310 JY8QFUQ01DPEN4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGLGAYYIYYFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctggattcacctttggcctctatgccatgaactGgggtccgccagactccagggaaggggccggagtggctcgcaactatcagtggtagtggaagtaggtcattctacgcagactccctcaggggccgtttcaccatctccagagacaattccaagggcacggtgtacctggacatgaccaccctgggagccgacgactcggccgtgtattactgtgccagagatggagtccgtggccttggtgcttattatatctactattttgactcatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14311 JY8QFUQ01BU8WP unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 342 61.75 134/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (61,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagaaatagtggtacttacacattttacgcagactccgtgtattactgtgcgaaagtttacaacagacactcgaccggatattgtagtggtggtagttgctactccggttatggaaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 14312 JY8QFUQ01BXXGZ No results 14313 JY8QFUQ01AG9YX unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW# out-of-frame + stop codons cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggcccaatgggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 14314 JY8QFUQ01C1FAL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14315 JY8QFUQ01CAZ6Y productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 991 94.98 208/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CGRPPLYSSGWQHPFNFW in-frame - ggttctggatacaactttaccgactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcccggtgactctgatatcacatatagtccgtccttccaaggccaggtcaccatctcagtcgacaagtccatcagcaccgcctacctgcagtggaacagcctgaaggcctcggacaccgccatgtattattgtgggagacccccactatatagcagtggctggcaacatccttttaatttctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14316 JY8QFUQ01BHN4V unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 302 96.88 62/64 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found ctctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaaggggctg 14317 JY8QFUQ01B3WD7 No results 14318 JY8QFUQ01C10TD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14319 JY8QFUQ01A9VP5 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame - tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14320 JY8QFUQ01BX5R1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14321 JY8QFUQ01BY6WB productive Homsap IGHV1-2*04 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARGDFFESSGFDYW in-frame - tggatacaccttcaccgcccactatatacactgggtgcgacaggcccctggacaagggcttgagtggatggggcggatcaaccctaatagtggtggcacaatttatgcacagaagtttcagggctgggtcaccatgaccagggacacatccatggacacagcctacatggaggtgagggggctcaaatccgacgacacggccgtctatttctgtgcgcgaggcgatttctttgagagtagcggctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14322 JY8QFUQ01DHN5R productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcatcccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14323 JY8QFUQ01CHFVD productive (see comment) Homsap IGHV3-7*02 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaagGggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttct 14324 JY8QFUQ01B0BBI productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ6*02 F 121 66.13 41/62 nt Homsap IGHD3-16*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARGGGSSKRQVKDYYNGLDVW in-frame + tggatacaccttcagcagttattatatacactgggtgcgacaggcccccggacaggggcttgagtggatggcaatgatcaacccaagtggtggtagtaccacgtacgcacagaagttccagggcagactcatcgtgaccagggacacgtccacgagtagtgtctacatggacctgagtagcctgagatctgaggacacgggcgtctatttctgtgcgagaggggggggttccagtaaacgtcaggtgaaggactactacaacggtctggacgtctggggccaagggaccagcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgaggtgtcgtggaactc 14325 JY8QFUQ01CGLZF No results 14326 JY8QFUQ01BLUPN unproductive Homsap IGHV3-7*01 F (see comment) 711 81.11 176/217 nt 80.18 174/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARLKGLTHHDFYFDL# out-of-frame - Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'GG' (2 nucleotides at position 125 to 126 in the user submitted sequence), (cause frameshift); ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatacTtttggggactctgtgaaGGgggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggcgtggcatcctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14327 JY8QFUQ01CG6VE unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 754 82.43 183/222 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 X 8.10.X [1.17.38.11] CATDSPYWI##AFDVW out-of-frame + stop codons Low V-REGION identity (82,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagtcgaggacggaggcttgtacttctgtgccacggattccccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14328 JY8QFUQ01BAHNB No results 14329 JY8QFUQ01CMLTU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 14330 JY8QFUQ01ABR6E productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgcagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaggag 14331 JY8QFUQ01ANSMV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDQSCIVGPCGFDYW in-frame - gcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgt 14332 JY8QFUQ01BQACL productive Homsap IGHV3-7*03 F 851 88.07 192/218 nt Homsap IGHJ6*03 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 and Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccagg 14333 JY8QFUQ01CJCDJ No results 14334 JY8QFUQ01CCACX productive (see comment) Homsap IGHV3-48*02 F 882 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASGGVTEAHYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); ctctggattcagctccagtgaatataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaggggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgggtgttTtattactgcgcgagcggaggggtgacagaggctcactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14335 JY8QFUQ01B4EUN unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggattcagcttcagtgactatggcatgggctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14336 JY8QFUQ01AW22E No results 14337 JY8QFUQ01BFTC4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14338 JY8QFUQ01AN0P3 productive (see comment) Homsap IGHV4-39*02 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.16.38.11] CARIVVRQFDQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaagggctggagtggattggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14339 JY8QFUQ01DDAXQ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 2 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) gtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14340 JY8QFUQ01CNJAZ productive Homsap IGHV4-34*03 F 890 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CVRNYYDFSGYFNWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtgggtccttcagtggttactactggagttggatccgccagcccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcancgctgcctggtcagggcttcttccc 14341 JY8QFUQ01CZIF6 productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14342 JY8QFUQ01DQ5IL No results 14343 JY8QFUQ01DMCPH productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARVGATLSFDVW in-frame - cctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagcgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 14344 JY8QFUQ01DM9QB unproductive Homsap IGHV4-61*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.37.11] CARESKVISCPNWFD#PW out-of-frame + in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift) tctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatcctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagggaaagtaaagtgatcagctgccccaactggttcgaccccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14345 JY8QFUQ01AXJWN productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14346 JY8QFUQ01CDE14 productive (see comment) Homsap IGHV3-48*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKGVIAVAGTTLTAG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatTgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggctgacggtgtcgtggaactc 14347 JY8QFUQ01AGTXI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14348 JY8QFUQ01B81A4 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 823 87.04 188/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame - tctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14349 JY8QFUQ01AODKR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1035 97.7 212/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14350 JY8QFUQ01A1W6G productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14351 JY8QFUQ01DMRBH productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 959 93.58 204/218 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14352 JY8QFUQ01ACU8V productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14353 JY8QFUQ01DHT73 productive Homsap IGHV4-61*02 F 1033 96.4 214/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [2.17.38.11] CARAPSYTNSHQHCDYW in-frame - gtctctggtggctccatcaacagtggtagttactactggagttggattcggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattattgtgcgagagctccctcttataccaactcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14354 JY8QFUQ01C2UOY productive Homsap IGHV3-72*01 F 931 90.67 204/225 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [2.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14355 JY8QFUQ01B14T7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14356 JY8QFUQ01APKCI unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CARPYCGGDCHNRGAF**SW in-frame + stop codons in FR3-IMGT at codon 76 of V-REGION: 'G' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttGcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggctttttgatagtcctggggccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccc 14357 JY8QFUQ01AJ98V productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 781 83.78 186/222 nt 82.43 183/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVIDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'GC' (2 nucleotides at position 108 to 109 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'GT' (2 nucleotides at position 128 to 129 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtactcattactattggggctggatccggcaGgcccccagggaggggactggagtgggttgggagtatccactacactgggagcaGCctacctacaactggtcccGTccaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatagactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14358 JY8QFUQ01A91DP No results 14359 JY8QFUQ01A8P07 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14360 JY8QFUQ01COINA No results 14361 JY8QFUQ01CMNZM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctctagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14362 JY8QFUQ01A4O9C productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt 84.86 185/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtaattacgacatgcactgggtccgccGaacctagaggaagaggtctggagtAgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14363 JY8QFUQ01C2AVU productive (see comment) Homsap IGHV1-8*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD2-2*02 F 3 8 8 14 8.8.14 [0.17.38.11] CARLAAPLRAYALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); ctggatacaccttcggcagttttgatatcaactgggtgcggcaggGcccctggacaagggcttgagtggatggggtggatgaaccctcacagtggtaacacaggatatgcagagaacttccagggcagagtcaccatgaccagggacacctccataagcacagcctacatggagctgagcagcctgacatctgacgacacggccgtatattactgtgcgagactagcagcacctttacgcgcctacgctttggacgtctggggccaagggaccgcggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14364 JY8QFUQ01ABVQT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14365 JY8QFUQ01A1E6T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 944 93.49 201/215 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [0.17.38.11] CARPFSGRWCFDLW in-frame - ctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14366 JY8QFUQ01BAI84 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.37.11] CAKDRTLHTPAQMFYYGMDV## out-of-frame - in FR3-IMGT, from codon 70 of V-REGION: 2 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) atctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14367 JY8QFUQ01AHV9E productive Homsap IGHV3-48*04 F 1039 98.15 212/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14368 JY8QFUQ01BGFM3 No results 14369 JY8QFUQ01A59BK No results 14370 JY8QFUQ01AZYI1 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 1 10 7 12 10.7.12 [2.17.38.11] CARHRNSGTYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcaacagtagagattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgGggggcaccttctacaacccgtccctcaagagtcgagtcaccttatccgtagacacgtccaggagccagttctccctgcagctgagctctgtgaccgccgcagacacggctgtttattattgtgcgagacatcgtaactctggaacctactttgacttctggggccggggatccctggtctccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14371 JY8QFUQ01A3PUT productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaAaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 14372 JY8QFUQ01AJ8R1 productive (see comment) Homsap IGHV4-61*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD6-13*01 F 2 10 7 19 10.7.19 [1.17.38.11] CAREAPKAAANSYNSYVMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 94 of V-REGION: 'AG' (2 nucleotides at position 191 to 192 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggcctggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctccctgaagctgacctctgtAGcaccgccgcagacacggccgtgtattactgtgcgagagaagcgcccaaggcagcagctaattcctacaactcttacgttatggacgtctggggccaagggaccacggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14373 JY8QFUQ01CRLTG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14374 JY8QFUQ01BPZU7 No results 14375 JY8QFUQ01C0RNL unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 799 86.38 184/213 nt 85.45 182/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD5-12*01 F 1 8 7 X 8.7.X [1.16.38.11] CAGEEMRTRDGGWLRNGRL# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctctggtggctccatgactctttattattggagttggatccggcagcccgcagggaagggctggagtggttgggtacatcgatcacgctgggagcgccaagtataacgcctcccttcagagtcgagtcaccatctcagtcgacgcgcccaagaatcagttctctctgaagttgaactctgtgactgctgcggacacggccgtttattactgtgcgggagaagagatgcgaacgcgggacgggggttggctacggaacggacgtctggggcccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14376 JY8QFUQ01B1QV9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 14377 JY8QFUQ01B1Q7T productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14378 JY8QFUQ01BI1XN productive Homsap IGHV4-39*03 F (see comment) 911 90.45 199/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] RTREGPYYYGMDVW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattaccgtacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14379 JY8QFUQ01B8VAJ unproductive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.38.11] CARDRGP*QLVQNGI#DYW out-of-frame - stop codons tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcgggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14380 JY8QFUQ01BNXAQ No results 14381 JY8QFUQ01C0HUJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKDPRLSGSMDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttagcatctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcagtggtgctagtacatactactcagactccatcaggggccggttcaccatcaccagagacaattccgagaacacgctttatctgcagatgaacagcctgagagccgacgacacggccgtatatttctgtgcgaaagacccccggctcagtggctcgatggactactggggccggggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14382 JY8QFUQ01CNBKQ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14383 JY8QFUQ01BKERP productive Homsap IGHV1-58*02 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame - tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14384 JY8QFUQ01CBGQK No results 14385 JY8QFUQ01CRB7S No results 14386 JY8QFUQ01BW499 No results 14387 JY8QFUQ01BSIE7 No results 14388 JY8QFUQ01AAZ6M productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14389 JY8QFUQ01AXNSW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14390 JY8QFUQ01CALGE productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14391 JY8QFUQ01AKEEE productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14392 JY8QFUQ01A86IT productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARERGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14393 JY8QFUQ01CGC96 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14394 JY8QFUQ01AN6X4 No results 14395 JY8QFUQ01C5Q4Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1003 96.3 208/216 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + tctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14396 JY8QFUQ01BTN82 No results 14397 JY8QFUQ01B83SF No results 14398 JY8QFUQ01APVYE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14399 JY8QFUQ01B091Q No results 14400 JY8QFUQ01ACLH9 productive Homsap IGHV3-72*01 F 962 92.41 207/224 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14401 JY8QFUQ01A3L04 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14402 JY8QFUQ01B2UA1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14403 JY8QFUQ01AO0V4 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 14404 JY8QFUQ01CEMV2 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcctcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcgtgcctggtccagggcttcttccccca 14405 JY8QFUQ01DENT6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14406 JY8QFUQ01ALYS4 No results 14407 JY8QFUQ01BXON5 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAREHDTGVATRYFDYW in-frame + cctctggattcgccttcagtctgtatcctatgcactgggtccgccaggctccaggcaagggactagagtgggtggcacttatctcctctgatggaagtgataagttttcctcagactccgtgaagggccgattcgccatctccagagacaattccaagaacacggtctatctacaagtggacagcctgagaactgaggacacggctatgtatttctgtgcgagagagcacgacacgggagtggcgacgaggtattttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14408 JY8QFUQ01CY3UN productive Homsap IGHV4-4*07 F (see comment) 872 89.77 193/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-22*01 F 2 10 7 22 10.7.22 [1.17.38.11] CARERAYDRNGFYYANRHNWLDTW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CY3UN ; 8 AA in Homsap_IGHV4-4*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcacatttggcagttactactggaattggatccggcagcccgccgggaagggactggagtgggtaggacgtatctatgcaagtgggaccacccattccaacccctctctcgagactcgagtcatcatgtcactagacacgtccaacaaccagatctccctgaagctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagaaagggcctatgatagaaatggcttttactacgcgaaccgccacaactggctggacacctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14409 JY8QFUQ01APTPO No results 14410 JY8QFUQ01CWR1L productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14411 JY8QFUQ01CUTQ0 productive Homsap IGHV3-48*02 F 876 90.19 193/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [0.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 14412 JY8QFUQ01A3R0S No results 14413 JY8QFUQ01BVXTP productive (see comment) Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaAagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14414 JY8QFUQ01BXZSI unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14415 JY8QFUQ01CMKX8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14416 JY8QFUQ01CE5NY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14417 JY8QFUQ01COVI0 productive Homsap IGHV3-9*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSGGYTHNYFDYW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14418 JY8QFUQ01ACV8E No results 14419 JY8QFUQ01AFYS4 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt 82.49 179/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaGggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaGggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14420 JY8QFUQ01B2GHU productive (see comment) Homsap IGHV4-61*02 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgcctccataaataggggtaattattactGggaactggatccggcagcccgccggggaaggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14421 JY8QFUQ01AITAG No results 14422 JY8QFUQ01BPN9H productive (see comment) Homsap IGHV3-7*02 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaagGggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14423 JY8QFUQ01A8ROM No results 14424 JY8QFUQ01BNUQT productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14425 JY8QFUQ01AZVG9 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 714 80.27 179/223 nt 79.82 178/223 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARERGASIGEAGGLDSW in-frame - stop codons Low V-REGION identity (80,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'CC' (2 nucleotides at position 33 to 34 in the user submitted sequence), (cause frameshift); tctcttgggtggccccgtcaacaaatggtgatCCagtattggagctggatccggcagcccgccgggaaggggctggagtggatcggacgtgtttctgctagtgggacctacagctacaatccctccctcaggagtcggatcaccatctcaatagacatgtctaagaatcacttctccctgaggttgatttctgtgacggccgcagacacggccttatattattgtgcgagagagcgtggtgcgtcgattggcgaagcgggaggccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14426 JY8QFUQ01AQPZZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctggattcagcttagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14427 JY8QFUQ01CW489 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 7 22 8.7.22 [1.17.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame - tctctggtgactccttcagaactcactactggagttggattcgacagcccccggggaggagattggaatggattggcaatatatattatattgggaccaccaactacaacccctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14428 JY8QFUQ01DAG7H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14429 JY8QFUQ01CNNQZ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 832 87.5 189/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcagtttcagtaccTtttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14430 JY8QFUQ01BBZNJ productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - cctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 14431 JY8QFUQ01A9SHR productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14432 JY8QFUQ01C2BMN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14433 JY8QFUQ01BF7UR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 118 50.72 106/209 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14434 JY8QFUQ01AN0QQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14435 JY8QFUQ01APJMN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacctTgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14436 JY8QFUQ01C4QN4 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14437 JY8QFUQ01DBWS0 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKVGSTVVG##FDYW out-of-frame + stop codons cctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagtagggtcgacggtggtagggggactttgactactggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14438 JY8QFUQ01C2I1T unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CMNELGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataCggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtcggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14439 JY8QFUQ01BV0EO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14440 JY8QFUQ01DL9WP productive (see comment) Homsap IGHV3-11*01 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14441 JY8QFUQ01C5ERR No results 14442 JY8QFUQ01AW1YP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14443 JY8QFUQ01CBK2S No results 14444 JY8QFUQ01BW9YU productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAREGVGGFDYW in-frame + cctctggattcacctttagtagctattggataagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaagcaagatgggagtaaggtggagtatgtgggctctgtgaagggccgattcaccatctccagagataatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagagggggtgggaggatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14445 JY8QFUQ01AQW3Z productive Homsap IGHV3-9*01 F 837 87.56 190/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaactttgatggtcatgccatgcactgggtccggcaagttccagggaagggcctagagtgggtcgcaggtattaagtcgaatggtgatgtccttggttctgtggactctgtgaagggccgaatcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14446 JY8QFUQ01BYZ7Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcagttccccgaaccggtgacggtcgtgcgtggaactca 14447 JY8QFUQ01DBJH1 unproductive (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGG**WTLE*LL# out-of-frame + stop codons tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaagggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14448 JY8QFUQ01A4EKY unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKTTMTSVT#DWFDPW out-of-frame + in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14449 JY8QFUQ01BV6AQ productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F 701 92.59 150/162 nt 91.98 149/162 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 X 7 12 X.7.12 [X.9.38.11] CARGSGSGSYSNLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccCctgaagntgcgctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14450 JY8QFUQ01CX24P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14451 JY8QFUQ01DPGMR No results 14452 JY8QFUQ01AIO4V productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt 83.41 181/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.16.38.11] CARDSALFGYARYDAMDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift) cctctggatccagtttcagtggttttggcgtgaactggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14453 JY8QFUQ01C1WUD unproductive Homsap IGHV3-30*07 F 863 89.3 192/215 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [0.17.38.11] CGKQLGAHKGADY## out-of-frame - ctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccataaaggggctgactactggggccagggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14454 JY8QFUQ01AT7QO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14455 JY8QFUQ01APZQG productive (see comment) Homsap IGHV1-3*01 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [0.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaGggcccccggacaaaGggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14456 JY8QFUQ01AG43S No results 14457 JY8QFUQ01AHEWI productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 998 94.2 211/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcgaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14458 JY8QFUQ01DVC4K productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14459 JY8QFUQ01A61WO productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 14460 JY8QFUQ01BVNEI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARHEGYNSRYYYFGYW in-frame + tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14461 JY8QFUQ01BJSH2 productive (see comment) Homsap IGHV3-9*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 7 11 8.7.11 [2.17.38.11] CGKDMRPGGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) gcctccggattcacctctGgaaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14462 JY8QFUQ01A4MG4 No results 14463 JY8QFUQ01BOQ3Q productive (see comment) Homsap IGHV3-33*05 F (see comment) 761 83.49 182/218 nt 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaaaGatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 14464 JY8QFUQ01DWDGD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttc 14465 JY8QFUQ01C9QGG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-1*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARRQLALAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); tggatacacctttatcacctactggatcgcctgggtgcgccaaatgcccgggaaAaggcctggagttgatgggagtcatctatcctggtgactctgagaccagatCacagcccgtccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactggggccagggaacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14466 JY8QFUQ01AHCVV No results 14467 JY8QFUQ01CISTZ No results 14468 JY8QFUQ01AT4EU productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD2-8*02 F 2 8 8 24 8.8.24 [1.17.38.11] CVRAAGYCPGGDDCYKIGTHDSLDIW in-frame + gtctggattcaccttcagtacctatggcacacattgggtccgccaggctccaggcaaggggctggactgggtggcagttagttggcatgatggaagtcaggaatattatgcagactccgtgaggggccgattcactgtctccagagacaattccaagaacacggcatatctgcatatgaatgtcctgagaggcgaagacacggctgtctactactgtgtgagagcggcggggtactgtcctggtggtgatgactgctacaagatcggaactcatgactcccttgatatctggggccgaggggcagttgtctccgtctcctctgcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 14469 JY8QFUQ01AYI64 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcag 14470 JY8QFUQ01DQPOL productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14471 JY8QFUQ01C82Q0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 797 85.32 186/218 nt 83.94 183/218 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'TGG' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'TA' (2 nucleotides at position 36 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcagcgttaagttcgttaTGGgcatgTAactggggtccgccaggctccatggggggggctggGagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14472 JY8QFUQ01B8D2N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggGggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14473 JY8QFUQ01CCMNU productive Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F 800 86.05 185/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREAPDGSVTYDYW in-frame + tctctagtggctccatcaatggtcactactgggcctggatccggcagcccgccgggaaggggctggagtggatggggcgcatctatgcaactggggtcaacaactacaatccctccctcaggagtcgagtcaccatgtcagtagacacgtccaacaaccgtctcttcctgagcttgacctctgttaccgccgcggacacggccatatattattgtgcgagagaggcccccgatggttcggtgacttatgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 14474 JY8QFUQ01BBKZT productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14475 JY8QFUQ01B888I productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 706 81.02 175/216 nt 79.63 172/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); gtctctgggttcaccatcagtCacgtactccatgggCctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgGcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14476 JY8QFUQ01DJMF5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARKRVPGGTFYGDYW in-frame - gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14477 JY8QFUQ01BKGRR No results 14478 JY8QFUQ01APZAB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14479 JY8QFUQ01BBDS8 productive (see comment) Homsap IGHV4-39*02 F 801 91.58 174/190 nt 91.05 173/190 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.6.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 31 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactgggggctgattcggggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14480 JY8QFUQ01C8V0W productive (see comment) Homsap IGHV3-9*01 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggcGtatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14481 JY8QFUQ01C0HLW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaAGggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14482 JY8QFUQ01BCBTW No results 14483 JY8QFUQ01DHPUD No results 14484 JY8QFUQ01AL0O1 productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [2.17.38.11] CAREQSSRGYPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcacctttgagacttattggttgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaAagcaagatggaagtgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatacccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14485 JY8QFUQ01CLM87 No results 14486 JY8QFUQ01ADGL2 productive Homsap IGHV3-7*01 F 896 90.37 197/218 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame - cctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14487 JY8QFUQ01AF8I8 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14488 JY8QFUQ01A8JNL productive (see comment) Homsap IGHV2-5*02 F 1071 93.44 228/244 nt 93.03 227/244 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 3 10 7 13 10.7.13 [9.17.38.11] CAHRRVGTATAFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagtaacagtggagtgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttggacacaCttttttgggatgatgataagcgctacagtccctctctgaaaagcaggctcaccctcaccaaggatacctccaaagaccaggtggtccttgaaatgaccaacatggaccctgtggacacagccacttattactgtgctcacagacgtgtggggactgcgaccgcttttgatttctggggccaggggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14489 JY8QFUQ01AF5K9 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14490 JY8QFUQ01B59TP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt 99.07 214/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14491 JY8QFUQ01BZB16 productive Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccttgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14492 JY8QFUQ01A1MAL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 10 7 20 10.7.20 [1.17.38.11] CAATMNYMSADSTGWYGGGDYW in-frame - tctctggtggctccatcaataataggctctactactggggctggattcgtcagcccccagggaagggtctggagtggattgggagcatccataatagtgggagcacctactacagtccgtccctcgagagtcgtgtcatcatctccgtagacacgtccaacaagcggttcttcctgaggctgagctctgtgaccgccgcagacacagctatgtactactgtgcggcaacgatgaattacatgtccgccgatagcactggctggtacggcgggggtgactactggggccagggagcctcggtcaccgtgtcctcagtatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14493 JY8QFUQ01BO2JV productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgtctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 14494 JY8QFUQ01CE5WC unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14495 JY8QFUQ01AVR4A productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcacctcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14496 JY8QFUQ01C2ENZ No results 14497 JY8QFUQ01AQCN4 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 990 95.39 207/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDRYTDSWFNGNWFAPW in-frame + ctctggattcacatttgatgaatatggcatgagctgggtccgccaatctccagggaaggggctggagtgggtctctggtattaattggaatggtgccagcataggttatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtttctgcaaatgaacagtctgagagccgaagacacggccttgtactactgtgtgagagacaggtataccgacagttggtttaatggaaactggttcgccccctggggccagggaacccaagtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14498 JY8QFUQ01AZMVL unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-21*02 F 1 8 7 X 8.7.X [1.17.38.11] CARGRTVVTVIDYIDY## out-of-frame + in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagAcccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggttcagggagccctggtcagcgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagactgggaacgtggtgtcgccatgcctggctccagggcttcttccccca 14499 JY8QFUQ01AMFYO productive (see comment) Homsap IGHV3-48*01 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14500 JY8QFUQ01ASQGX productive (see comment) Homsap IGHV3-11*01 F 872 89.77 193/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaGggctccagggaaggGggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca 14501 JY8QFUQ01AU02Q productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD1-1*01 F 1 10 7 14 10.7.14 [1.17.38.11] CARELGNTERGIVDPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcgacactagttatcactgggcctggatgcgccagcccccagggaagggcctggagtggattgctaatgttcattatactggcagcgcccactacaacccgtccctcaagagtcgagtcaccatactagtagacacgtcccagaatcagttctccctgatgctgagttctgtgaccgccacagacacggctgtgtattactgtgcgagggaacttggtaatactgagaggggaatcgtcgacccctggggccagggaatcccggtcagcgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14502 JY8QFUQ01CJOHM productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame - cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctcccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14503 JY8QFUQ01ANAJP productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14504 JY8QFUQ01AJQN5 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14505 JY8QFUQ01DMPOP unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 905 90.83 198/218 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRHTAMERGDY## out-of-frame + gttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggccccgggaaccctggtcaccgtcacctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14506 JY8QFUQ01BKQBZ productive Homsap IGHV3-48*02 F (see comment) 724 81.48 176/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14507 JY8QFUQ01DQV9H productive (see comment) Homsap IGHV3-11*01 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'CG' (2 nucleotides at position 71 to 72 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctctggaattcagcttcagtgactactacatgagtTtgggtccgccaggctccagggaagggactggagtCGggatttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14508 JY8QFUQ01CHPCA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 14509 JY8QFUQ01A0ZX6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 14510 JY8QFUQ01AMOBY unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRGCGNGACHVADY## out-of-frame + cctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 14511 JY8QFUQ01B8ACY unproductive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14512 JY8QFUQ01AS6B9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14513 JY8QFUQ01B3JZW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 88.99 194/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - cctctggattctccgtcagtaattactggatgcactgggtccnccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagattactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 14514 JY8QFUQ01BK5EM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgccctggtccagggcttcttccc 14515 JY8QFUQ01C3WVN No results 14516 JY8QFUQ01AITB3 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 6 10 9.6.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatgtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14517 JY8QFUQ01DA9DR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKKHYNSGTYLYNFDYW in-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14518 JY8QFUQ01AXCM5 productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14519 JY8QFUQ01AS8ER No results 14520 JY8QFUQ01BZ0SZ No results 14521 JY8QFUQ01APBH8 No results 14522 JY8QFUQ01BDTVE No results 14523 JY8QFUQ01AJL9X No results 14524 JY8QFUQ01B75FJ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 14525 JY8QFUQ01CEZA3 productive (see comment) Homsap IGHV3-9*01 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [2.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); gcctctggattcaccGtttcatgattataccatgGcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14526 JY8QFUQ01AAXKV productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14527 JY8QFUQ01A6MYW productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1033 96.4 214/222 nt 95.5 212/222 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 10 17 7.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) ttctggatcacctttggtgattaGtagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14528 JY8QFUQ01BXKGT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 725 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); cctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14529 JY8QFUQ01DLJI4 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 92.86 208/224 nt 91.52 205/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD1-14*01 ORF 1 8 7 X 8.7.X [4.17.38.11] CARGDPIFM#*C out-of-frame + in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); cctctgcagcctctggattcattgtcaatagcaactacatgagttggGgtccgccaggctccagggaaggggntGggactgcgtctcagttatttatcccggtgGgtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccattttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14530 JY8QFUQ01CZ5KL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ5*02 F (see comment) 237 96.08 49/51 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDAALLAAAGDNWFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacatttgacgactacggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcccttattagtggtggtggtggcagcacatactatccagactccgtgaagGggtcggttcatcgtctccagagacaattccaagaacatgttgtttcttcaaataaacaacctgaaaatcgaagacacggccgtttatttttgtgcgaaggacgcggcccttctagcagctgccggggacaactggttcgacacctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14531 JY8QFUQ01AG5LX productive (see comment) Homsap IGHV3-74*03 F (see comment) 702 80.65 175/217 nt 80.18 174/217 nt Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTTGWRGVDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaacgtcagtggatactggatgcactGgggtccgccaagtgccagggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14532 JY8QFUQ01DJ04F unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDG#YW out-of-frame - ctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14533 JY8QFUQ01C4SH0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14534 JY8QFUQ01CGSSK unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKRFGPPH#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14535 JY8QFUQ01AROP7 productive (see comment) Homsap IGHV3-66*02 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgAaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14536 JY8QFUQ01DHU9P productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 786 85.51 183/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcaccgactacttcatacactggctgcgactggcccctgaacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaattatgcacggaactttcagggccgggtcaccatgacccgcgacacgtccgtcagaacagtatatgtggaggtgaacagcctgaaatctgacgacacagccatttattactgtgcgcgaggcttttatggtgaccactttgactcctggggccagggagccgtggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14537 JY8QFUQ01AHUWU No results 14538 JY8QFUQ01DPATU unproductive Homsap IGHV3-7*01 F 1005 95.45 210/220 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSDFYSTGYW# out-of-frame - agcctctggattcagctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtttttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14539 JY8QFUQ01AYIXT unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14540 JY8QFUQ01BYPF6 No results 14541 JY8QFUQ01CE1SQ unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14542 JY8QFUQ01C546L productive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14543 JY8QFUQ01CKAX8 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1054 96.05 219/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctaccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14544 JY8QFUQ01CV905 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14545 JY8QFUQ01BH736 No results 14546 JY8QFUQ01AN6BM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDIW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacatctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgtggaactc 14547 JY8QFUQ01CXANI productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 14548 JY8QFUQ01AO0LA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14549 JY8QFUQ01CJ9DH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 14550 JY8QFUQ01DPDZW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 85.58 184/215 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD5-24*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CATLRGVLSTSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagCcccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaaccCcctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggtactttcgactagctggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgccctggtcaaggactacttcccccgaaccggctgacggtgtcgtggaactcag 14551 JY8QFUQ01C9BZF unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 562 73.15 158/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.6] PV## out-of-frame - Low V-REGION identity (73,15% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14552 JY8QFUQ01BR8PW No results 14553 JY8QFUQ01CHOA5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14554 JY8QFUQ01CXLRG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGHSYYVSSGPDYW# out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14555 JY8QFUQ01BLZ8Q productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 928 91.78 201/219 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - gcctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14556 JY8QFUQ01DMCYI productive (see comment) Homsap IGHV1-18*01 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tggttacccctttaatacctatggtatcacctgggtgcgacaggcccctggacacggccttgagtggatggGggtggatcagcgttcacgatggcaacacaaactatgcacagaatctccagggcagagtcaccctgaccacagacacatctacgagcacagcctacatggaactgaggggtctcagatctgacgacacggccgtttattattgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaattggtcatcgcctgcctggtccagggcttctc 14557 JY8QFUQ01BJRSQ No results 14558 JY8QFUQ01CVGIT productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaattc 14559 JY8QFUQ01CIDLV productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaagacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14560 JY8QFUQ01BGL40 productive Homsap IGHV4-39*03 F 939 91.44 203/222 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [2.17.38.11] CARSITLTVVVMNDAFDVW in-frame - tgtctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14561 JY8QFUQ01DD88M productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14562 JY8QFUQ01CEH6F unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 14563 JY8QFUQ01APM60 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1034 98.14 211/215 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 15 8.7.15 [1.17.38.11] CARGVGVSWHTEYFQHW in-frame + cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 14564 JY8QFUQ01ANF78 unproductive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDWSSMVRGSF##DHW out-of-frame - stop codons gctctggattcaccttaagtagccatcagatgagctgggtccgccaggctccagggaaggggctggagtgggtggctaagataatccaagatggaagtgagacatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagtcgaggacacggctgtgtattactgtgcgagagattggtcctctatggttcgggggagtttcaattgaccactggggccagggaaccctgcttaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14565 JY8QFUQ01ADGA2 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 841 87.96 190/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CARILTLFAVVTSSGMDV#W out-of-frame + tctggatttaccttcagtaattatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggccgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtcttggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccacgccagatgggaacgtggtcgtcgcatgcctggtccagggcttgcttcccccag 14566 JY8QFUQ01AH38B productive (see comment) Homsap IGHV4-61*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tttctggtggccccatcagaggcggtggtttctactggacctggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 14567 JY8QFUQ01B38ZE productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgagggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14568 JY8QFUQ01DT6Z6 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 975 95.33 204/214 nt 94.39 202/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatatacactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtttaCtttttgtgcgagagacggatattgtagtacgaagaattgcttcgccaagaccgacttcgtttgggggaccataaactactggggccagggatgccctggtcgccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctcgtgcaggcgttcttccccca 14569 JY8QFUQ01CATUZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 974 95.75 203/212 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 7 8 14 7.8.14 [X.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14570 JY8QFUQ01DN11O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 14571 JY8QFUQ01CM5PB productive (see comment) Homsap IGHV3-7*03 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); agcctctggattcagttttagtGaccttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14572 JY8QFUQ01A9CIV productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattcacCctttggttattatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14573 JY8QFUQ01CXVCW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14574 JY8QFUQ01C3YHE productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14575 JY8QFUQ01AVLD8 productive (see comment) Homsap IGHV3-7*01 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); gcctctggcttcacctttgaaaattatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14576 JY8QFUQ01CP1MJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14577 JY8QFUQ01CGJJT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1014 95.91 211/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) agcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14578 JY8QFUQ01ALEYX productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccctag 14579 JY8QFUQ01CGNIA productive (see comment) Homsap IGHV4-39*02 F 952 91.89 204/222 nt 91.44 203/222 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [2.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) tgtctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14580 JY8QFUQ01CSL9Y unknown (see comment) Homsap IGHV3-74*03 F 104 52.94 72/136 nt 8 7 X 8.7.X [2.17.11.X] null + No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14581 JY8QFUQ01CK5TA productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt 14582 JY8QFUQ01DNLDV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - cctttggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14583 JY8QFUQ01AFD8Q No results 14584 JY8QFUQ01BF9SP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cgtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgGggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14585 JY8QFUQ01B8IVO No results 14586 JY8QFUQ01APYJS productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame + ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14587 JY8QFUQ01BU3VU productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + tctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 14588 JY8QFUQ01B36OI unproductive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDYW# out-of-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccaaaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 14589 JY8QFUQ01BIP32 unproductive Homsap IGHV3-9*01 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKWGRALVRGLIPVQLVR#PW out-of-frame + cctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggcaacataggctatgcggactctgttaagggccgattcaccatctccagagacaacgacaagaactccctgtatctgcaaatgaacagtctaagacgtgaggacacggccttctattactgtgcaaaatgggggagggctttggttcggggacttatcccagtacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14590 JY8QFUQ01C1H8N No results 14591 JY8QFUQ01B7XXQ productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 922 90.22 203/225 nt 89.78 202/225 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-24*01 ORF 3 8 10 17 8.10.17 [2.17.38.11] CSRGLGDGYNLGYHALDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcttctggattcagttttggtgattattctatgatctggttccgccaggcaccggGggaaggggctggagtgcgtaggtttcattagaagcagagcatatggtgggacaacacaatacgccgcgtctgtgaaagacagattcaccatctcaagagatgatcccaaaggcatcgcctatttgcaaatgagcagtctgaaagtcgacgacacaggcgtgtatttttgtagtcggggattaggcgatggctacaatctgggttatcatgcccttgatatctggggccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagccctcgacagcaccccccaagatgggaacgtggtcgtcgccatgcctggctccagggcttcttccc 14592 JY8QFUQ01C65WZ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14593 JY8QFUQ01ADY7Y No results 14594 JY8QFUQ01BIUEK productive Homsap IGHV3-66*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 7 13 8.7.13 [2.17.38.11] CASRVAARQGYFDNW in-frame - agcctctggattcaccgtcggtagtaattacatgaactggatccgccaggctccagggaaggggctggagtggatctcagttatttataccggtggtagtacatactacgtggactccgtgaggggccgattcaccatctccagagacaattccaagaacacgctgtatcttcaaatgaacagcctgagagctgaagacacggctgtgtattactgtgcgagccgtgtagcagctcgtcagggctactttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14595 JY8QFUQ01DD8IM No results 14596 JY8QFUQ01ACYZU No results 14597 JY8QFUQ01CE7GX productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1071 99.54 216/217 nt 98.62 214/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacgttcagtagctatagcatgaactggGgtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14598 JY8QFUQ01DMUKG productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14599 JY8QFUQ01C8GQ3 productive (see comment) Homsap IGHV3-23*05 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 14600 JY8QFUQ01AUHXT No results 14601 JY8QFUQ01DHIV6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.16.38.11] CARDTLEVVSNMDDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cctctggattcatcttcagtcgttGatagcatgaactgggtccgccaggctccagggaagggctgagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14602 JY8QFUQ01BUUWC productive (see comment) Homsap IGHV3-49*04 F (see comment) 809 84.82 190/224 nt 83.93 188/224 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD3-3*01 F 2 8 10 16 8.10.16 [1.17.38.11] CARDRDYHDSWPDSFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'T' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift); cttctggattcaccttaggtgattaTttgtctaatgtgggtccgacagtttccagggaagcgacTtggagtgggtaggcttcattagaagtgcactttttggtgggaccacagaatacgccgcgtctgtgaaaggaagattcaccatctcaagagatgactccgagggcatcgcccacctagagatgaacagtctcaacaccgaggacacagccgtgtattattgtgctagagaccgcgattatcacgatagttggcccgattcttttgatgtctggggcccagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14603 JY8QFUQ01AWC8L productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14604 JY8QFUQ01AEJJ5 No results 14605 JY8QFUQ01BFOJ9 productive Homsap IGHV3-30*01 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVREERAGAAYYFRYW in-frame + cctctggattctcctttagaacctacgctatgcactgggtccgccaggctccaggcaaggggctacactggctggccgttataacatatgatggaagtaataaatattacgcggactccgtggagggccgcttcaccatctccagagacaattccaagaagaccctttatctgcaaatggacagcctgagaggtgaggacacggcggtctattactgtgtgagagaggaaagagcgggagccgcttactactttcgctactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14606 JY8QFUQ01B98S6 unproductive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVRGYYGGQYFDSW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggctggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggcccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14607 JY8QFUQ01CKNTI productive Homsap IGHV3-30*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatattttttctatgcactgggtccgccaggctccaggcaagggactagagtgggtgtcacttgtttcatatgatggatctaagaaaaagtacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14608 JY8QFUQ01AD591 No results 14609 JY8QFUQ01A1U7S productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 669 79.44 170/214 nt 78.97 169/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataGggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacatatttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14610 JY8QFUQ01AH5YV productive (see comment) Homsap IGHV3-30*07 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.16.37.11] CASLGSYESSGPRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 74 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggattcctcttcagtagttatgctatacactgggtccgccaggctccaggcaaggggcttgagtgggtgcggttgtttcatatgatggaaataataaatttacgcagactctgtgaagggtcgattcagcctctccagagacaactccaagagcacggttgatctgcaaatggacaacttgagatccgaagacacggctgtatattattgtgcgagcctcggttcctatgagagcagtggtccccgatggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14611 JY8QFUQ01BWET8 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 7 11 8.7.11 [2.17.37.11] CARDRQSWGIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaaggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgctagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14612 JY8QFUQ01C1V5R unknown (see comment) Homsap IGHV1-NL1*01 P 84 56.41 44/78 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccaga 14613 JY8QFUQ01DRERH unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt 8 7 X 8.7.X [4.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14614 JY8QFUQ01B4QGR productive Homsap IGHV4-39*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame - tctctggtgactccatttccagtactagttattactggggctgggtccgccagccccagggaaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14615 JY8QFUQ01DCK7H productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 852 85.59 196/229 nt 85.15 195/229 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [3.17.38.11] CTSNSWLDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tgcagcctctggattctcGtttcagtaatgcctggatgaactgggtccgccaggctccagggaaggggctggaatgggttggccatataaaaagggacatcgatggtggcatagcaaactacgcaacatccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgcaaatcgaagactcaggcgtttattactgcacctcaaattcgtggctcgaccgctggggccagggtaccaccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14616 JY8QFUQ01BZNFS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 917 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CANWLSGTHSKFDYWG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CA' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift); tctggattcacccttCAggcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctganagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactgggggcaagggaagcccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 14617 JY8QFUQ01CJBMZ unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARRQQLRDFDYW in-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatttgcactgggtgtgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggagacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14618 JY8QFUQ01CEUYJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14619 JY8QFUQ01AMG29 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); tggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtGgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14620 JY8QFUQ01AYJXD productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14621 JY8QFUQ01DJU83 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARPLVDHEDSGYLPSG in-frame - cgtctggattcaccttcagtgactatgccatcctctgggtccgccagactccaggcaaggcgctggagtgggtggcagttatatggcatgatgggagtgaaaagttctatgccgactccgtgaagggccgtttcaccatctccagagacaattccaagaagaccctttatctggaaatgagcaatctgagagccgaggacacggctgtgtatttctgtgcaaggcctcttgtggaccatgaagatagtggttatctgccttctgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14622 JY8QFUQ01DKZQV productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 962 92.41 207/224 nt 91.96 206/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 7 7 8 7.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) ccgtctgcagcctctggattcattgtcaatagcactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14623 JY8QFUQ01A8H2O productive (see comment) Homsap IGHV3-7*02 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) agcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14624 JY8QFUQ01BLMKY No results 14625 JY8QFUQ01CCERP No results 14626 JY8QFUQ01BF1FJ productive Homsap IGHV3-48*03 F 888 89.55 197/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARESWWSGFYGWYDPW in-frame - agcctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14627 JY8QFUQ01B84FR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cagcctccgaattcatccttnacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14628 JY8QFUQ01B9EP0 unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 549 72.81 158/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] YC**RTWIQ*LRP#DYW out-of-frame + stop codons Low V-REGION identity (72,81% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgcctgcatgacttaccgttcggtcgacacgacggctgtcttattattgttagtaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14629 JY8QFUQ01DTWKQ unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1000 95.43 209/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CVRGDYGGDPRTLLRP#YGLDVW out-of-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaacgggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgacccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14630 JY8QFUQ01AOR4M productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14631 JY8QFUQ01B9YFD No results 14632 JY8QFUQ01C8K7Q unknown (see comment) Homsap IGHV3-9*01 F 1017 96.77 210/217 nt 95.85 208/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggattcagGatttgatgaGttatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14633 JY8QFUQ01BYFTC productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14634 JY8QFUQ01AMV93 productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + cctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14635 JY8QFUQ01C3KZ3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatganctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14636 JY8QFUQ01B54IS unproductive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaaggggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14637 JY8QFUQ01BL6V1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 750 83.64 179/214 nt 83.18 178/214 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 7 18 8.7.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BL6V1 ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacAaccctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14638 JY8QFUQ01CJ967 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaagggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14639 JY8QFUQ01BI54H unproductive Homsap IGHV3-11*01 F 851 88.07 192/218 nt Homsap IGHJ2*01 F 157 77.36 41/53 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CADINWV#WCFDLW out-of-frame + cctctgaaatcaccttcagcgaccactacatgagctggatccgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14640 JY8QFUQ01BRF9W unproductive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14641 JY8QFUQ01ANR0Z productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14642 JY8QFUQ01DTI0K productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); tctctggCtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14643 JY8QFUQ01CZ5H7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 108 53.33 72/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14644 JY8QFUQ01BZ5GU unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 819 97.66 167/171 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found cctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc 14645 JY8QFUQ01CCSL0 productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + cctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14646 JY8QFUQ01DUY4L productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD6-6*01 F 2 8 10 16 8.10.16 [1.17.38.11] CTRRSIADNFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); tctgggttcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagcaaagctaacagttacgcgacagcatatgctgcgtcggtgAaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtactagacggagtatagcagataacttctactactacggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14647 JY8QFUQ01AU0JI productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14648 JY8QFUQ01B1XIV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14649 JY8QFUQ01CU3FW unknown (see comment) Homsap IGHV3-66*02 F 743 92.44 159/172 nt 91.86 158/172 nt 8 7 X 8.7.X [4.16.21.X] null + No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaagggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta 14650 JY8QFUQ01BNJCF No results 14651 JY8QFUQ01AT0AG No results 14652 JY8QFUQ01A0D0L No results 14653 JY8QFUQ01A8VTH productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1045 95.61 218/228 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 14654 JY8QFUQ01A7BV6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-3*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGYDFWSTYRGYNWFDPW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctcttacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgctgcggacacggccgtgtattattgtgcgagaggttacgatttttggagtacatatcgtgggtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14655 JY8QFUQ01AO7UP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); ctccgggagttcacctttagtagtttctGggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14656 JY8QFUQ01A3L37 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame + tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 14657 JY8QFUQ01A0XAA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + cgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14658 JY8QFUQ01CLLOA productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14659 JY8QFUQ01AQJ09 No results 14660 JY8QFUQ01CHMWW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 760 83.8 181/216 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14661 JY8QFUQ01CQQYZ productive Homsap IGHV3-9*02 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnnccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14662 JY8QFUQ01A3RHW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 425 76.35 113/148 nt 75.68 112/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (76,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggacaacataatgccagatggaggtgagAaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca 14663 JY8QFUQ01B0SHL unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); gcctctggattcacCctttaacaactaCggccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14664 JY8QFUQ01BGTOW unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14665 JY8QFUQ01CTO8B productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARVNKDSTDMW in-frame + ctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaagggggctggagtgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtgctcttcagcatccccgaccagccccaaggtcttcccgctgagctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccccag 14666 JY8QFUQ01A7HR7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt 14667 JY8QFUQ01BBCX9 productive Homsap IGHV3-30*15 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame + tctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14668 JY8QFUQ01CJRRG productive (see comment) Homsap IGHV4-61*02 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgcctccataaataggggtaattattactGggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14669 JY8QFUQ01BZWQB No results 14670 JY8QFUQ01DIS4R productive Homsap IGHV3-11*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14671 JY8QFUQ01AKDFZ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14672 JY8QFUQ01BGAKM No results 14673 JY8QFUQ01CCUFF productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14674 JY8QFUQ01DI4E3 No results 14675 JY8QFUQ01AOMW2 productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14676 JY8QFUQ01AJJIF unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 14677 JY8QFUQ01DLUV5 productive (see comment) Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 190 to 190 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagaGggcgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14678 JY8QFUQ01AP8WK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); ctcaggattcacgtttagcaggtatgccatgaactCgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgataCctggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14679 JY8QFUQ01CWT79 No results 14680 JY8QFUQ01A98LD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14681 JY8QFUQ01CZJ6H productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14682 JY8QFUQ01CE9X2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1014 95.91 211/220 nt 95.0 209/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'TC' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtagtagttactactggggctggatccgccagTCccccagggaaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtAccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14683 JY8QFUQ01A0005 productive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14684 JY8QFUQ01CJLXD productive Homsap IGHV1-58*02 F 925 92.96 198/213 nt Homsap IGHJ6*02 F 188 84.62 44/52 nt 8 8 9 8.8.9 [X.17.38.11] CVADRNGFDVW in-frame - ggattcaccttcgctagttcgtctatacagtgggtgcgacagactcgtggacaacgccttgagtggataggatggatcgtcgttggcagtggcaacacaaagtacgcacagaagttccagggaagagtcacctttaccaaggacatgtccacaagcacagccttcatggagctgaacaacctgagatccgaggacacggccgtgtattactgtgtggcagatcgaaacggtttcgacgtctggggccaagggaccacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14685 JY8QFUQ01AUYLV No results 14686 JY8QFUQ01BSGO4 productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctagattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcc 14687 JY8QFUQ01BN5MB productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14688 JY8QFUQ01BS58Q productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 861 88.18 194/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14689 JY8QFUQ01CNW0Z unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F 619 87.97 139/158 nt 8 8 X 8.8.X [1.17.18.X] null - No rearrangement found ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggcttcttccccca 14690 JY8QFUQ01AL269 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*01 F (see comment) 90 60.32 38/63 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctgggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14691 JY8QFUQ01BC9RZ productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1020 97.66 209/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD6-13*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARASSAWYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tggatacaccttcaccagttactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtagcacaagctacgcacagaagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtgtacatggaggtgagcagcctgagatctgaggacacggccgtgtatcactgtgctagagctagcagcgcctggtacggtctagacgtctggggcctagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14692 JY8QFUQ01CMXI4 productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGGTVTAGGPRIVFGYW in-frame - tggctacaccttcaccgactactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctgacggtggtagcacaaagtatgcacagaaatttcagggcagggtcgccgtgaccagggacacgtcaattagcacagcctacattgaggtgaccagactgacatctgacgacacggccgtgtattattgtgccagaggagggactgtgacagcaggtggtcctcgtattgtctttgggtactggggccagggaacgttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14693 JY8QFUQ01DATSJ productive Homsap IGHV3-11*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFDYW in-frame + cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggatttcatacattagtgggagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccagggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacggccacgtattattgtgtgaggcgggtctggggatacagttatggttccgtttcgtattacttcgactactggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14694 JY8QFUQ01AEM97 productive Homsap IGHV3-74*03 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARHKPLGATSLDYW in-frame - gcctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggctgtatattattgtgcgagacataagccactgggagctacaagccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 14695 JY8QFUQ01C3UHK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctncctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 14696 JY8QFUQ01A5VJ3 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame - tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14697 JY8QFUQ01AU8Z8 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDFIMV#DYW out-of-frame - ctctggattcaacttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagactttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14698 JY8QFUQ01B20JA No results 14699 JY8QFUQ01CF5U2 productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGMDVW in-frame + cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgccctggtcccagggcttcttccccc 14700 JY8QFUQ01DL6EM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREGGGAVRRK#YFDYW out-of-frame - cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcggggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14701 JY8QFUQ01AE7R4 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGGVSGAFRWG#FDYW out-of-frame + stop codons ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtggggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14702 JY8QFUQ01CDCCZ No results 14703 JY8QFUQ01DKEJK productive Homsap IGHV3-64*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + ctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 14704 JY8QFUQ01C85KU productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcg 14705 JY8QFUQ01BKM97 No results 14706 JY8QFUQ01BMC0P productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14707 JY8QFUQ01BIDEZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtgtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14708 JY8QFUQ01BRTW7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt 8 8 16 8.8.16 [1.17.38.11] CVKDVISFGALIVFNLNI (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcagatttagcagctatgccatgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatgtgatttcctttggggcacttatcgtcttcaacttgaacattgggcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14709 JY8QFUQ01DWT03 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [2.16.38.11] CAKDQSCIVGPCGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gcctccgaattcatccttgacagttatgccatgagttgggnccgcaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14710 JY8QFUQ01CKXCL No results 14711 JY8QFUQ01DFGYO unproductive Homsap IGHV3-48*04 F 958 93.98 203/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGRIVSVGMSGWF##PW out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'A' (1 nucleotides at position 150 to 150 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); tctggactcaccttcagcagctatagtatgaactgggtccgccaggctccagggaaAGggggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattcaccatctccagagacAaacgccaagaacaccctgtatctgcaAaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgaacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14712 JY8QFUQ01BRYU1 No results 14713 JY8QFUQ01BE108 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWGADAFDIW in-frame + cctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14714 JY8QFUQ01C3KUP No results 14715 JY8QFUQ01DKQXX unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtgaactc 14716 JY8QFUQ01CICNZ unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14717 JY8QFUQ01ADUL0 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 773 84.65 182/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARRSNPNAMMAAFDIW in-frame - stop codons Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggattcagtcctagccgactttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaacggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14718 JY8QFUQ01A0XM8 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccaggacccagagaaagggactgagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14719 JY8QFUQ01DSKY7 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tctggattcacgttcagtagctactggatgcactgggtccgccGaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14720 JY8QFUQ01B15SH unproductive Homsap IGHV4-61*01 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CTRGGSTLMT#PW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcggtagtactaactactggagctggattcggcagcCccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgagggggggcagtacacttatgacagcccgtggggacaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14721 JY8QFUQ01C4T4X productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14722 JY8QFUQ01BICD9 unproductive Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGGNGDLDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14723 JY8QFUQ01CAJVK productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [X.17.38.11] CTHLREEMSYEW in-frame - tggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14724 JY8QFUQ01CKGRK productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14725 JY8QFUQ01CIOUS productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14726 JY8QFUQ01CR92I unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14727 JY8QFUQ01CZX1A No results 14728 JY8QFUQ01B5YXL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame - gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14729 JY8QFUQ01DIN2T productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14730 JY8QFUQ01BCX6Z unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRVVLMVHAMS#DFW out-of-frame - cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcgggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14731 JY8QFUQ01CPKXR No results 14732 JY8QFUQ01A7NCV unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F (see comment) 266 57.8 126/218 nt 57.34 125/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (57,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); ggtctggatacatctttaatatccactggatcgcctGgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14733 JY8QFUQ01DDV4B productive Homsap IGHV3-7*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggagacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14734 JY8QFUQ01ABZVD productive (see comment) Homsap IGHV3-7*01 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.37.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcccgaggacacggctgtatatttctgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14735 JY8QFUQ01BIZYH unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 916 90.54 201/222 nt 90.09 200/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 9 X 8.9.X [1.17.38.11] CTTDRRGFVYTTS#FDFW out-of-frame + stop codons in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggccgtataaaaacaaagctatgggtgagacaacagacttcgctgcacccgtgagaggcagattcagtatctcaagagatgattcaaaaaatacactgtatctgcacatgagtggcctgaaaaccgaggacacagccgtctattattgtaccacagatcggcggggttttgtctataccacctcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14736 JY8QFUQ01A7XAB productive Homsap IGHV4-4*07 F 890 90.7 195/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLPTVTTGALDIW in-frame + tctctggtggctccttcagtaattaccactggagctggatccggaagcccgccgggaaggaactggagtggattgggcgtatccatcacagtgggctcaccaactccaacccctccctcaagaatcgagtcgtcgtgtcagtggatacgtccaagaatcagttgtccctggagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcctacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14737 JY8QFUQ01AGGN2 No results 14738 JY8QFUQ01AKHCX productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtaccaaGgttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14739 JY8QFUQ01BDGDZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14740 JY8QFUQ01BCKQ8 No results 14741 JY8QFUQ01CYIFV No results 14742 JY8QFUQ01CXQDP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14743 JY8QFUQ01CTYTD productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14744 JY8QFUQ01B1HDC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactgGgggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 14745 JY8QFUQ01ATVGB unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 14746 JY8QFUQ01AXWIG productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14747 JY8QFUQ01C0QH5 productive Homsap IGHV3-66*02 F (see comment) 759 84.11 180/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame + Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14748 JY8QFUQ01BVMIC productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [2.17.38.11] CARRDVGSHAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); ggggttctggatTacaattttaactacgactggatcgGgctgggtgcgccagatgcccgggaaaggcctggagtggatggggatggtctatgttggtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14749 JY8QFUQ01CJK0W productive Homsap IGHV3-30*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + cctctggattcaacttcaggacctattctatgcactggctccgccaggctccaggcaagggactagagtgggtatcagttatttcatatgatggaactaagaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctacaaatggacagcctgagacctgaggacacggctgtgtattactgtgcgagagatgaactgccttgggatacaatagagtattactttgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 14750 JY8QFUQ01B7XFX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14751 JY8QFUQ01B212Y unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [2.17.38.11] CARAKSSDPSQLVR#PG out-of-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgagagcaaaaagtagtgatccgtcccaactggttcgacccctggggccacgggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14752 JY8QFUQ01BFOHN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 752 82.65 181/219 nt 80.82 177/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 16 8.8.16 [2.17.38.11] CAMRFCGGPECYPYLDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); gcctctgggttcacattcagtGaactactggatccactgggtccgccaagctccaggaaaAGggggctanagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcGacatttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggGaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14753 JY8QFUQ01AJUBJ unproductive Homsap IGHV4-61*02 F 834 86.82 191/220 nt 85.91 189/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 1 10 7 X 10.7.X [1.17.37.11] CARCPNYNIGTPG#FDYW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 217 in the user submitted sequence), (cause frameshift) tttctggtgtctccatgagcaatgAgtccctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatattctgtgcgaggtgtcccaattacaacattgggaccccggggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14754 JY8QFUQ01CZG7X productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggatcacctttggttattgatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14755 JY8QFUQ01DKTDW No results 14756 JY8QFUQ01BKDOO productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 917 92.09 198/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 7 10 8.7.10 [1.17.38.11] CARGGLEPVDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14757 JY8QFUQ01AFMA5 No results 14758 JY8QFUQ01ANQVZ productive Homsap IGHV3-13*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - agcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14759 JY8QFUQ01ANTUE No results 14760 JY8QFUQ01BNITY productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 919 91.32 200/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) ggcctctggattcaccCtttggttattatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14761 JY8QFUQ01ADBSF productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 864 88.94 193/217 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 14762 JY8QFUQ01CC2VZ productive Homsap IGHV3-66*02 F (see comment) 759 84.11 180/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARHLMVYALDVW in-frame - Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14763 JY8QFUQ01BYPS6 productive (see comment) Homsap IGHV4-61*07 F 905 90.83 198/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 9 7 13 9.7.13 [2.17.38.11] CAREDGSGRRHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AG' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) gtctctgggtgactccatcaacagggtggttatttctgGgagctggatccgccagcAGcccacgggaagggcctggtgtggattggGgtacatctattacaGgggggagcacctactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14764 JY8QFUQ01CGHQQ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 697 80.56 174/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame - Low V-REGION identity (80,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14765 JY8QFUQ01BMECE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFEYW in-frame + ctctggattcaccttcagcagctatggcatgcactggttccgccaggctccaggcaaggggctggagtgggtggcagctatctcatatgatggaattgacaaatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaaacacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgcccctggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 14766 JY8QFUQ01CQMR7 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPPSGNLR*LR##W out-of-frame + stop codons cctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagacccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14767 JY8QFUQ01C5GP7 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14768 JY8QFUQ01A3IBC No results 14769 JY8QFUQ01BM2F6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 1 8 8 12 8.8.12 [1.17.38.11] CGKQLGAHKGADYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccataaaggggctgactactggggccaggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14770 JY8QFUQ01BYW33 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14771 JY8QFUQ01AWIJ1 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 782 85.12 183/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14772 JY8QFUQ01AK3ZY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - tctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14773 JY8QFUQ01BBT9T No results 14774 JY8QFUQ01AQH68 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + gctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtggtggtgatagcacatactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14775 JY8QFUQ01CG6PQ productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14776 JY8QFUQ01A26A4 unknown (see comment) Homsap IGHV3-48*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcagcttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccataaactatgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcagggcttcttcccc 14777 JY8QFUQ01BQEVD No results 14778 JY8QFUQ01AHFYO unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARLGQLALDY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgGggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactgggggcgagggaaccctgatttccgtctcctcagcctccaccgaacgggcccatcggtcttccccctggcaccctcctgccaagagcacctctgggggcacagcggccctgggctgcctcggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14779 JY8QFUQ01B5BYX unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 14780 JY8QFUQ01CANBH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctaggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14781 JY8QFUQ01BRUUK unproductive Homsap IGHV3-72*01 F 926 90.62 203/224 nt 89.29 200/224 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-8*02 F 3 8 10 X 8.10.X [2.16.38.11] CTRDTTDTGGQSFNGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggtttccCccttcagtgaccacttcatggactgggtccgccagctccagggaagggcctggagtAgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctgggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14782 JY8QFUQ01C7OY5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 14783 JY8QFUQ01CBC07 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt 77.06 168/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIIREGLDRW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); tgtctggtggttctactcgcactaaccattggtCggaattgggtccgccagAccccccgacaagggactggagtggattggagaagtctataagagtggacagaccaactacaacccgtcactccagagtcgcgttgacctcttcattgacaactccaggaatcagatctccctaaatatgagagatgtgaccgccgcggacacggccgtctattactgcgcgagagaagacattattcgggagggccttgaccgctggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14784 JY8QFUQ01C86EV productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgtgacggtgtcgtggaaactca 14785 JY8QFUQ01AD2KE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14786 JY8QFUQ01B5QQQ No results 14787 JY8QFUQ01CNFQ4 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CARHEGYNSRYYYFGY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggcccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgctgcctggtccagggcttcttcccccaa 14788 JY8QFUQ01AR87F unproductive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CATSPFTVTTGKDAY## out-of-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggcccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14789 JY8QFUQ01COGA1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14790 JY8QFUQ01CO8CK productive (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaAaaactctaactacaaccCcctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagccctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14791 JY8QFUQ01C531H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaAaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14792 JY8QFUQ01ACLFY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 2 8 8 10 8.8.10 [1.17.38.11] CVKDLLGGDPFW in-frame + ctctggattcaccttcagtcgctatggcttgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcagatgatgggaagaataaattctatacagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgatgtttgtgcaaatgaacagtctgagagctgaggacacggctgtgtattactgtgtgaaagacctactaggtggtgaccccttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14793 JY8QFUQ01BBYXJ unproductive Homsap IGHV3-7*03 F 892 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKDASRYYYNSYCDN## out-of-frame + in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggGccaacataaaggaagacggaagtgagagatattatgtggactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 14794 JY8QFUQ01ALGAH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERSAAGVVFFDF# out-of-frame - cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttgggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14795 JY8QFUQ01AO8B3 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 927 92.17 200/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14796 JY8QFUQ01AM7WT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattaggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14797 JY8QFUQ01DXF6K productive Homsap IGHV3-48*01 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDASWSYYAYFDSW in-frame - tctggattcaccctcagtagcaacagcatgaactgggtccgccagactccggggcaggggctggagtgggttgcacacattagtagtagcagcgataccatatactacgcagactctgtggggggccgattcaccatctccagagacaatgccaagaactcactgcatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagagatgccagttggagctactacgcttactttgactcttggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14798 JY8QFUQ01CI6IF unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-21*01 F 2 9 7 X 9.7.X [1.17.38.11] CTSREHALVVNSR#DYW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'GTC' (3 nucleotides at position 24 to 26 in the user submitted sequence), (do not cause frameshift); tgtctggtgtctccgtcaccagcGTCagtcactggtggacctgggtccgccagcccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgctttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14799 JY8QFUQ01CEE4G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 92.0 184/200 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 3 8 11 3.8.11 [X.17.38.11] CARFGPLTRPDYW in-frame - ccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14800 JY8QFUQ01BT291 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [2.17.38.11] CARRLNNYDSGEYAMDV## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgGggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctgggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14801 JY8QFUQ01AL4SS unproductive (see comment) Homsap IGHV4-61*01 F 934 91.44 203/222 nt 90.54 201/222 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-16*01 F 3 10 7 X 10.7.X [2.17.38.11] CTKGGIHL*QPV# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcggtagtactaactactggagctggattcggcagGCccccaggggaagggactggaattcattgGggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaagggggggatacacttatgacagcccgtgggggacaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14802 JY8QFUQ01CCETR No results 14803 JY8QFUQ01AWZVZ No results 14804 JY8QFUQ01CMUK3 unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 849 88.79 190/214 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGGFQ*TSGEG#YYNGLDVW out-of-frame + stop codons tggatacaccttcagcagttattatatacactgggtgcgacaggcccccggacaggggcttgagtggatggcaatgatcaacccaagtggtggtagtaccacgtacgcacagaagttccagggcagactcatcgtgaccagggacacgtccacgagtagtgtctacatggacctgagtagcctgagatctgaggacacgggcgtctatttctgtgcgagaggggggggcttccagtaaacgtcaggtgaagggactactacaacggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 14805 JY8QFUQ01A2QA6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14806 JY8QFUQ01C8EBK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14807 JY8QFUQ01DGDK1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame - ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14808 JY8QFUQ01BHLLE productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame - ctctggattcacctttagtaaccattggatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14809 JY8QFUQ01CW7XW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctggattcatcttcagtagctatgccatgaattGgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14810 JY8QFUQ01C4YTG unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNM#DAFDLW out-of-frame + stop codons cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatgatgatgcttttgatttgtggggccaagggacagtggtaatgtctcctcagcatccccgaccagcccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 14811 JY8QFUQ01AUEHV No results 14812 JY8QFUQ01CF445 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CAKEEVPNDYW in-frame - ctctggattcacctttagcaatgctgccatgacgtgggtccgccaggctccagggaaggggctagagtgggtctcaggtattagtattagtggtgatagaacatattacgcagactccgtgaagggccggttcaccatctctagagacaattccaagaataccgtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14813 JY8QFUQ01B4DOI productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [2.17.38.11] CARAPGWMNPFDFW in-frame - tgtctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14814 JY8QFUQ01AYG9W unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPLYNWN#YFYYYGMDVW out-of-frame + tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcaaccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccctgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 14815 JY8QFUQ01CFFY3 productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 14816 JY8QFUQ01AEFZP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAEKKHYNSRTYLYNFDY## out-of-frame - ctctgggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcggaaaaaaaacattataattcgaggacttatttatacaactttgactactgggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14817 JY8QFUQ01DBMZV No results 14818 JY8QFUQ01CJBSY productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-19*01 F 1 10 7 10 10.7.10 [1.17.38.11] CAAYDSGWYKHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 99 of V-REGION: 'T' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctggagtggattggatacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtctaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacTggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttcccc 14819 JY8QFUQ01CE327 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDDKWAFDYW in-frame - cctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaggggctagattgggtggcatttatatcatatgatggaagtaatgagttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14820 JY8QFUQ01DJBEG productive (see comment) Homsap IGHV3-74*03 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) cctctggattcactttccacacctcctggatgcactgggtccgccaagtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 14821 JY8QFUQ01B3XMD productive (see comment) Homsap IGHV3-7*01 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CGRDERGADLPNDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggGactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14822 JY8QFUQ01C1GNB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14823 JY8QFUQ01AK7F3 productive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggcttcaccttcagtgactactacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 14824 JY8QFUQ01CDGUR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14825 JY8QFUQ01DSGAI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDYGDCRGGRCYAEPLDY## out-of-frame + cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 14826 JY8QFUQ01CB5QB No results 14827 JY8QFUQ01CSFFN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 800 86.05 185/215 nt 84.19 181/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CAT' (3 nucleotides at position 54 to 56 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagtTtggatccggcagcccccCATgggaaagggacCtggagtggCattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14828 JY8QFUQ01A3WMR No results 14829 JY8QFUQ01A3MRK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14830 JY8QFUQ01AEEU6 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14831 JY8QFUQ01BNARW unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-16*01 ORF or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-20*01 F 70 100.0 14/14 nt 3 X X 3.X.X [1.X.X.X] null - No rearrangement found ctctggattcacct 14832 JY8QFUQ01C717G productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 666 78.34 170/217 nt 77.88 169/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 50 to 51 in the user submitted sequence), (cause frameshift); gtctggtggctccatcgccacttatcattggtggaattgggtccgccagACcccccggggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 14833 JY8QFUQ01AFU95 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 781 83.78 186/222 nt 82.88 184/222 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 9 13 8.9.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctgggttcGattttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14834 JY8QFUQ01BH6T6 No results 14835 JY8QFUQ01ALZYF productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccCttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14836 JY8QFUQ01BV1X0 unproductive Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFS#YYSGLDVW out-of-frame - tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgaccctttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14837 JY8QFUQ01DD1NB unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14838 JY8QFUQ01AA69Z productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14839 JY8QFUQ01B6K22 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14840 JY8QFUQ01DONE0 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + ttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14841 JY8QFUQ01AUIH8 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14842 JY8QFUQ01CDF4N No results 14843 JY8QFUQ01CUYC1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.37.11] CAKEEGATGVYYVDHW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgagggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14844 JY8QFUQ01DRGHF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDTGQWKDFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggcccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccgag 14845 JY8QFUQ01BJ9JS No results 14846 JY8QFUQ01CTT8H productive (see comment) Homsap IGHV3-48*04 F 1009 95.89 210/219 nt 95.43 209/219 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 7 8 16 7.8.16 [2.17.38.11] CARDAGGSGWYLYYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtagtataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacggcctgagagccgaggacacggctgtttattcctgtgcgagagatgcggggggcagtggctggtacctttactactttgactcctggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14847 JY8QFUQ01B3WRU No results 14848 JY8QFUQ01A8SI6 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14849 JY8QFUQ01B81Q2 productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14850 JY8QFUQ01CTCYU productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14851 JY8QFUQ01AXCOP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14852 JY8QFUQ01BICWG productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14853 JY8QFUQ01B8TTF No results 14854 JY8QFUQ01CCU4L unproductive Homsap IGHV2-5*02 F 1044 92.21 225/244 nt 91.39 223/244 nt Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-21*01 F 1 10 7 X 10.7.X [9.17.38.11] CTHRRRYCEGADCFGGAFD#W out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 31 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctccgggttctctctcagGcacttctgGgagtgggtgtgggctggatccgtcagcccccaggaaaggccctagagtggcttgcagtcatttattgggatgacgagaggcgctacagtccatctctgaggagcggcctgaccatcaccaaggacacttccaaaaacgaagtggtccttacaatgaccaacgtggaccctatggacacagccacatattactgtacacacaggaggcgttactgtgagggcgctgactgctttggtggtgcttttgattctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14855 JY8QFUQ01BFBI1 productive (see comment) Homsap IGHV3-7*02 F 861 92.08 186/202 nt 91.58 185/202 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 5 8 9 5.8.9 [1.15.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 15 nucleotides (from position 20 in the user submitted sequence), (do not cause frameshift) ctctggattcctttttagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag 14856 JY8QFUQ01BWN4T productive Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 863 89.3 192/215 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - tgtctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14857 JY8QFUQ01B1Q8U unproductive Homsap IGHV3-48*01 F 1085 99.54 217/218 nt 99.08 216/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CASIFGSGSPWG#YYYGMDVW out-of-frame + in FR3-IMGT at codon 94 of V-REGION: 'C' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcCctgagagccgaggacacggctgtgtattactgcgcctcgatttttgggagtggttccccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 14858 JY8QFUQ01BN0IG productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14859 JY8QFUQ01AOE9Z unproductive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKEEFDTGWTQPGD## out-of-frame - ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactgggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14860 JY8QFUQ01A9Y7T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14861 JY8QFUQ01DL5OF unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 997 96.71 206/213 nt 96.24 205/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.16.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 43 in the user submitted sequence), (cause frameshift) tctgggtggctccatcagtagttactactggagctggatccgcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14862 JY8QFUQ01C2RVY productive Homsap IGHV3-48*03 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14863 JY8QFUQ01CC1F0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 14864 JY8QFUQ01BWUL4 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14865 JY8QFUQ01CTC8T productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 90.19 193/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14866 JY8QFUQ01AUHKU productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14867 JY8QFUQ01A2TC0 No results 14868 JY8QFUQ01C1LYN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14869 JY8QFUQ01B8RUV productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [2.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14870 JY8QFUQ01B56F9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14871 JY8QFUQ01CKHXI No results 14872 JY8QFUQ01A4XXA productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatcatcctggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14873 JY8QFUQ01B4F4Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDYGNCGGGRCYSIPLDYW in-frame + cctctggatttacctttagccgctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcattattgatgttaattctttcacatactacgcagactctgttcggggccggttcaccgtgtccagagacgattccaagaacacggtatatctgcaaatgaacagtttgagacccgacgacacggccgtttattattgtgtgaaagattacggtaactgtggtggtggtcgctgctattcgattccccttgactactggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14874 JY8QFUQ01AY1X8 No results 14875 JY8QFUQ01CEEUJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRDDDTSGHYSLFKYW in-frame + gtctggattctcctttagtgcatatggcatacactgggtccgccagactccaggcaaggggctggagtgggtggctgttatgtattttgatggagttagaacattttatgcagactccgtgaagggccgattcaccctctccaaagactattccaagaacacggtgcatctgcaaatgaacagcctgcgagccgaggacacggctgtatattactgtgtgagagatgatgataccagtggtcactactctctgtttaaatattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14876 JY8QFUQ01BQZIL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.37.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 67 of V-REGION: 1 nucleotides (from position 107 in the user submitted sequence), (cause frameshift) ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatacactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 14877 JY8QFUQ01BC11J No results 14878 JY8QFUQ01CUXC6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 868 89.35 193/216 nt 87.5 189/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctggattcaGattttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtGcggtggtgttaattggaaTtgggggcagcgcaggttatgcagGtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14879 JY8QFUQ01BYI85 unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 14880 JY8QFUQ01AWT13 productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAREWAASHFDHW in-frame + cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 14881 JY8QFUQ01APDAE No results 14882 JY8QFUQ01ALWLG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14883 JY8QFUQ01BYEHM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggGggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14884 JY8QFUQ01A01ZH unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1115 100.0 224/224 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame - ctgtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14885 JY8QFUQ01B2GMI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [0.17.38.11] CARLGQLALDYW in-frame + gggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14886 JY8QFUQ01DOF6Y productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); ctctggtgactccgtcagcagtgataactggtggagGttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatgGgtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14887 JY8QFUQ01AD2FI unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 940 93.06 201/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARKGPQKRWLPTAM#DMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggcccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14888 JY8QFUQ01BH5J8 No results 14889 JY8QFUQ01CN5EM No results 14890 JY8QFUQ01CZ3D6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcaatttttgcatgacctgggtccgccaggctccagGggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14891 JY8QFUQ01BEXBU productive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [2.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14892 JY8QFUQ01B8536 No results 14893 JY8QFUQ01CL9EO productive Homsap IGHV4-4*07 F (see comment) 683 80.0 172/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARESTNSIGDPRHLDSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CL9EO ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggccccatcaacacacatgacttctattggacgtggatccggcagtccgccgggaggggactggagtggctcggacgtgtctatatgaatggcattagtgaccacaatccagtcttcactagtcgtctcaccatgtccattgacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggactcggccctatattactgtgcgagagaaagtactaattcgattggcgacccgagacaccttgactcttggggccagggaaggttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 14894 JY8QFUQ01ASVBI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtgcgtggaactcag 14895 JY8QFUQ01CEP8T No results 14896 JY8QFUQ01C1J8G productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cgccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14897 JY8QFUQ01CPX03 productive (see comment) Homsap IGHV3-7*03 F 864 88.94 193/217 nt 87.56 190/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'G' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaagGgggctggagtgggtggccaacattcacgaagaAgggaagtgaaaagaattatgtggactctgtgaagggccggttcGtccatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14898 JY8QFUQ01BJYH6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [1.16.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggaggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14899 JY8QFUQ01DGXOJ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactacctggggccagggaaatcctggtcaccgtctctcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14900 JY8QFUQ01B2S3P productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14901 JY8QFUQ01C4TB9 unproductive Homsap IGHV3-7*01 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARVGGDYNDDHKYYLDY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) gctctggattcaTcatttggacactattggatgagttgggtccgccagattccagggaagggtctggagtgggtggccaacatacaacaagataggaagaattattatctggactctgtgaagggccgatttaccatctccagagacgacgccgggaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatatattactgtgcgagagtgggtggtgactataacgacgaccacaagtattaccttgactactggggccgggggagtcctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 14902 JY8QFUQ01AK176 productive Homsap IGHV3-7*03 F 826 87.79 187/213 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [X.17.38.11] CTRRGFMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14903 JY8QFUQ01BH5QO productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 14904 JY8QFUQ01CBSLO productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatCggggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14905 JY8QFUQ01BDMY2 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 86 57.53 42/73 nt 56.16 41/73 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagaga 14906 JY8QFUQ01BURWS productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14907 JY8QFUQ01CAQ0D unproductive (see comment) Homsap IGHV4-61*01 F 952 92.34 205/222 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD3-16*01 F 2 10 7 X 10.7.X [2.17.38.11] CTKGGIHL*Q#PW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) gtctctggtggctccatcagcggtagtactaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccagttctccctgaggctggcgtctgtgaccgctgcggacacggccgtgtattactgtacgaagggggggatacacttatgacagcccgtggggacaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14908 JY8QFUQ01AUKYE productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 849 87.0 194/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-22*01 F 2 8 10 11 8.10.11 [1.17.38.11] CTWDSTGYFRLTW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaaggggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctgggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgggtccagggcttcttccccca 14909 JY8QFUQ01CV1WC No results 14910 JY8QFUQ01C0J50 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1045 95.61 218/228 nt 95.18 217/228 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [2.17.38.11] CTRGSSRGGRYDENYYELDF## out-of-frame + in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaAagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggcccagggaaccctggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg 14911 JY8QFUQ01B8GKK productive (see comment) Homsap IGHV4-61*02 F 906 90.45 199/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERSISIGGARELDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'GTTTATAGTAGT' (12 nucleotides at position 87 to 98 in the user submitted sequence), (do not cause frameshift); ctctggcggccccatcaacagtggtcgttattactGggacctggatccggcagcccgccgggaaggggctggagtggatcggacgtGTTTATAGTAGTctttatacaagtgggaccaccgactacaatccctccctcaggagtcgagtcaccatgtcagtagacacgtccaagaagcagttctccctgaagttgacctctgtgaccgccgcagacacggccgtatattactgtgcgagagaacgtagtatttcgattggcggagcgagagaacttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14912 JY8QFUQ01A9WTH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 864 88.94 193/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'TC' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift); tccgggattcacctttagtagtttctGggatgcactggGgtccgccaagttTCccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14913 JY8QFUQ01AM4ZR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 14914 JY8QFUQ01BJP01 productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14915 JY8QFUQ01AX3WD productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14916 JY8QFUQ01APXXU unknown (see comment) Homsap IGHV3-7*03 F 135 51.69 107/207 nt 8 8 X 8.8.X [1.17.34.X] null + No rearrangement found ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14917 JY8QFUQ01C2GMG productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 14918 JY8QFUQ01C71ZZ unproductive (see comment) Homsap IGHV4-4*07 F (see comment) 557 73.49 158/215 nt 73.02 157/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARVRDAYTAGHFDS* in-frame - stop codons Low V-REGION identity (73,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'CT' (2 nucleotides at position 36 to 37 in the user submitted sequence), (cause frameshift); tctctggtgactctgtcactatgtcttattggggcCTgggatacgtcagcccgccgggggaggcctggagttaattggacgaacttctgccagtccaaaagttacctacaatccctccctcaggagtcgagccaccatattcgaagacacttcaaagaatcaacttatcttgaaattggcctctgtgaccgccgcggacacggccatctactactgtgcgagggtccgtgatgcctacaccgctggacactttgactcctgaggcccgggaaccctggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14919 JY8QFUQ01A6B0R No results 14920 JY8QFUQ01BGP7O No results 14921 JY8QFUQ01B6W83 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtGggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14922 JY8QFUQ01AL16A unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDY* in-frame - stop codons cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactagggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14923 JY8QFUQ01AO23Y productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 7 8 15 7.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) gtctggatcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14924 JY8QFUQ01CY4HO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 797 85.32 186/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgcgtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14925 JY8QFUQ01DK0ZZ productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.16.38.11] CARVIPGRGNYAFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcgactttggtagttattggatgagttgggtccgccagctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14926 JY8QFUQ01AL2Y7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1034 98.14 211/215 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14927 JY8QFUQ01APVLM No results 14928 JY8QFUQ01DQLS5 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 76 60.38 32/53 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagataggcgtgggtatagttatgaaatggactactgggggacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14929 JY8QFUQ01BJDP3 productive (see comment) Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 98.17 215/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcaccGttcagtagctatagcatgaactgggtccgGccaggctccagggaaggggctggagtgGggtttcatacaGttagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14930 JY8QFUQ01C283O No results 14931 JY8QFUQ01AFT98 unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14932 JY8QFUQ01CG9V4 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 669 78.97 169/214 nt 78.04 167/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcattgggtccgccaGggctccagggaAaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14933 JY8QFUQ01CESL5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + tctggattcactttccacacctactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14934 JY8QFUQ01DE51M unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 885 88.34 197/223 nt 87.0 194/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [2.17.38.11] CTNDHSMAVSAKHAF*CL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); tgtctctggtgcctccGatgagcaCgtagtgcatactactggggctgggtccgccagAAcccccgggaagggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgctttttgatgtttgggggtccagggacaatggtcaccgtctcttcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14935 JY8QFUQ01ABJ9P unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 14936 JY8QFUQ01B8J0R productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame + tttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14937 JY8QFUQ01CSXI9 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14938 JY8QFUQ01BTIFU unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14939 JY8QFUQ01B3XWC unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 861 90.05 190/211 nt 89.1 188/211 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD5-18*01 F 1 7 7 X 7.7.X [0.17.38.11] CAREFRAPSLARYGMDV## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) cggggttcagcgtcagtaataactcatgacctgggtccgccaggttccagggaAaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagtctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctgggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14940 JY8QFUQ01CDDA1 productive Homsap IGHV3-9*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD6-6*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKGARSSLYHALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattctgccatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaggtattatttggagtagtgctaacataggctatgcggactctgtaaagggccgcttcaccatctccagagacaacgccaagaattccctttatctacaaatgaacagtctgagagtagaggacacggccttgtattattgtgcaaaaggggcaaggtcgtccctctatcacgctttggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 14941 JY8QFUQ01AQ85X productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARHYDSSGYYSDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagcacttatagcatgaactgggtccgccaggCccccagggaaggggctggagtgggtcgcattcatgagtagtactagtaggtatatatattatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaatagcctgagagccgaggacacggctgtctattactgtgcgaggcactatgatagtagtggttattacagtgatgcttttgatatctggggccaagggacaatggtcacggtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14942 JY8QFUQ01A7C1U productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14943 JY8QFUQ01AQ8IY unproductive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDPYNGGGYGAFDI## out-of-frame + cctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgctaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14944 JY8QFUQ01DJI2E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14945 JY8QFUQ01DJP18 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 14946 JY8QFUQ01C6IY1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift); gcctgtggattccccCTtttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14947 JY8QFUQ01CQPSE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14948 JY8QFUQ01DQP4Z No results 14949 JY8QFUQ01AES3L unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 14950 JY8QFUQ01C57G2 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1013 94.27 214/227 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 10 9 X 10.9.X [1.17.38.11] CARRALDSSGHYIDI## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14951 JY8QFUQ01AG93B productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) cctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14952 JY8QFUQ01AC0UT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.16.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) gcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccgaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14953 JY8QFUQ01B830G unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.37.11] CMNELGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 89 of V-REGION: 1 nucleotides (from position 172 in the user submitted sequence), (cause frameshift) gcctctggattcacAttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtattgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtcggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14954 JY8QFUQ01BM3TF productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CARGHRNPGVWDLGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); ctacagtgggtccttcagtggttacctctggacctggatccgccagtcccccgggaaggggctggagCtggattggagaaattaattatagtgggagaaccaactacaacccgacccttgagagtcaagtcaccatttctgtagacacgtccaagaaccaattctccctgaagcttacctctgtgaccgccgcggacacggctgtctattactgtgcgagaggtcacagaaatccgggagtttgggacctcggtctggacgtctggggccaggggaccacggtcatcgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14955 JY8QFUQ01B0222 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 782 84.65 182/215 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGEECRSGSCYSVWFDPW in-frame + Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtgggtccttaagtgactcctactgggcctggatccgccagcccccagggaagggcctggagtacattggggagatcagtcatgatggtagaaccatgttcaattggtccctcaagagtcgactcaccatctcagtagacacgtccaagaatcaattctccctgagattgacctctgtgaccgccgcggacacggctgtttattactgcgcgagaggcgaggaatgtcggagtggaagttgctactccgtttggttcgacccctggggccagggagcccaagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14956 JY8QFUQ01AC5LX No results 14957 JY8QFUQ01AAQL2 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 925 90.99 202/222 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 1 10 7 12 10.7.12 [2.17.38.11] CAWGWFGLNYFDYW in-frame - gtctctggtggctccgtcagaagtaccagttactactggggctggatccgccagcccccagggaaggggctggagtggattagtaacattcattctagtggaaccacctactacaacccgtccctcaacagtcgagtcaccatgtccgtaaacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggctgtatattactgtgcatgggggtggttcggactgaactactttgactactggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14958 JY8QFUQ01CGPNS productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame - tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14959 JY8QFUQ01B7CJU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGQRYCSNGVCSSFFDS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 14960 JY8QFUQ01DG11T productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14961 JY8QFUQ01BHKRI No results 14962 JY8QFUQ01ACKNS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14963 JY8QFUQ01CUXMH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14964 JY8QFUQ01AH1G7 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDREPFYDFWSGFGWSGWTS# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cactggattcaccttcagttcctacaccatggaatgggtgcgccaggctccagggaaggggctggagtggctctcctcaattagtagtagtggtagttccatctcctacgcagactcagtgaggggccgattcaccatttccagagacgacgccgggaactcactgcatctgcaaatgaacagcctgagagtcgaggacacggctgtttattattgtgcgaaagatcgtgaaccgttttacgatttttggagtggttttggttggtccggatggacgtctggggccagggaccacggtcatcgtctcctcaagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14965 JY8QFUQ01B1W7W No results 14966 JY8QFUQ01BNXLT productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [1.17.38.11] CARGDGYNFGGLDYW in-frame + ctctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14967 JY8QFUQ01A1AWW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 233 57.65 113/196 nt 8 8 X 8.8.X [1.17.31.X] null + No rearrangement found Low V-REGION identity (57,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggatccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14968 JY8QFUQ01DT42Q productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggttcttcccc 14969 JY8QFUQ01DA7JF productive Homsap IGHV3-72*01 F 949 91.56 206/225 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-15*01 F 1 8 10 11 8.10.11 [2.17.38.11] CTPWWRGGYFDYW in-frame - gcctctggactcaccttcagtgcccagtacttagactgggtccgccaggctccagggaagggactggagtgggttggccgtattagaagcaaaactaacagttacaccacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaaccatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtaccccgtggtggcggggaggttactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14970 JY8QFUQ01C36PX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 14971 JY8QFUQ01BPUIM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1071 99.54 216/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14972 JY8QFUQ01ANO0O No results 14973 JY8QFUQ01CKEMG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14974 JY8QFUQ01CPBOG productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14975 JY8QFUQ01CVWCY productive Homsap IGHV4-61*02 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARGYCSNAVCYQIMNW in-frame + tctctggtggctccatcagcagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctctgggggcacancggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14976 JY8QFUQ01AOFPE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14977 JY8QFUQ01BYD6M productive (see comment) Homsap IGHV3-11*01 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [2.16.38.11] CADIKLGDWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) gcctctgaaatcaccttcagcgaccactacatgagctggatcgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14978 JY8QFUQ01C256P productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14979 JY8QFUQ01BS0TJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 931 92.59 200/216 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtatattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14980 JY8QFUQ01AVO1E No results 14981 JY8QFUQ01AQYA8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14982 JY8QFUQ01CYLRD productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggtaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 14983 JY8QFUQ01CXQJM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - ctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14984 JY8QFUQ01CBXPQ productive (see comment) Homsap IGHV4-4*07 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tgtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14985 JY8QFUQ01DN616 No results 14986 JY8QFUQ01AC3MC unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt 85.98 184/214 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD1-26*01 F 2 8 7 X 8.7.X [1.17.37.11] CATLRGGYFRLL# out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaaccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggggtactttcgactactggggccgggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14987 JY8QFUQ01AHP8Y productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame - tctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14988 JY8QFUQ01A8SUT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'T' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgaTcgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14989 JY8QFUQ01CJ5PW productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 14990 JY8QFUQ01BBZP7 No results 14991 JY8QFUQ01A17OX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNEFGYCSGG# out-of-frame + gctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgctccaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 14992 JY8QFUQ01CH6SP productive Homsap IGHV3-9*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKPGVVGLVPYYFDYW in-frame - ctctggattcacctttgatgattatgccatgcactgggtccgcaagcgtccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagcataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcaaaaccgggggtagtgggtctagttccgtactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 14993 JY8QFUQ01C5UCI unproductive Homsap IGHV3-11*04 F 919 90.87 199/219 nt 89.95 197/219 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [2.17.38.11] CASGGVTEAHY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); gcctctggaGttcaccttcagtgactactacatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaggGggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgggtgtttattactgcgcgagcggaggggtgacagaggctcactactgggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 14994 JY8QFUQ01AS3DP unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 105 100.0 21/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattcactttcagtaa 14995 JY8QFUQ01AZJWC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 14996 JY8QFUQ01DVY3B productive (see comment) Homsap IGHV3-9*01 F 820 86.3 189/219 nt 85.39 187/219 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [2.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgacgactatgtcatgcattgGggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatCggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14997 JY8QFUQ01BZIWN No results 14998 JY8QFUQ01DSDDA productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 975 93.27 208/223 nt 92.38 206/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); ctctggattcaacttcggtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcAaaagctgatgatgggacaacagaatacgccgcgtctgtgaaAaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 14999 JY8QFUQ01BVMDG productive Homsap IGHV4-39*02 F (see comment) 776 83.71 185/221 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARHLTNSDVVHHFYSGVDVW in-frame - Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcagtaatgataattatttctgggcctgggtccgccagtccccagggaagggtctgcagtggattggcagtatgtattatagtgggggcaccttttacgacccgtccctcaagggtcgaatcaagttgtccgttgacgtgtcgaagagccacttcctcctgaacctgacctctgcgaccgccgcagacacggctgtctattactgtgcgaggcatttgaccaactcagatgtggtccatcacttctactccggagtagacgtctggggcctcgggaccacggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15000 JY8QFUQ01AZ1TF No results 15001 JY8QFUQ01BX3ZQ No results 15002 JY8QFUQ01BFNOC productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 983 94.12 208/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 164 81.63 40/49 nt Homsap IGHD2-21*02 F 3 8 8 7 8.8.7 [2.17.38.11] CARMTDDFW in-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tagtctctgggttcaccctcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggttgcatacattagtagtagtggtagcaccataatctacgcagactctgtgaagggccgattcaccatctccagagacagtgccaagagctcactgtatctgcaaatgaacagcctgggagtcgaggacacggctgtgtattactgtgcgagaatgacagacgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15003 JY8QFUQ01A3YXB No results 15004 JY8QFUQ01BRNJL productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + ctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15005 JY8QFUQ01BIKN4 No results 15006 JY8QFUQ01CIWSW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15007 JY8QFUQ01AOFCE productive Homsap IGHV3-30*01 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - aggcctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15008 JY8QFUQ01BI38O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 15009 JY8QFUQ01BPGN6 productive (see comment) Homsap IGHV3-7*02 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [0.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 8 in the user submitted sequence), (cause frameshift) tggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15010 JY8QFUQ01B9F39 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 732 82.71 177/214 nt 82.24 176/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.16.38.11] CARDWGGSFDRYYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift) tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15011 JY8QFUQ01DBDGW productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15012 JY8QFUQ01BAXTU unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 1021 96.76 209/216 nt 96.3 208/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.16.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaagggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15013 JY8QFUQ01DM1DN No results 15014 JY8QFUQ01BRJOR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 15015 JY8QFUQ01AXU9Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctggattcacctacagcagcGtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15016 JY8QFUQ01A2G06 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 20 8.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15017 JY8QFUQ01CE15S No results 15018 JY8QFUQ01COPBQ No results 15019 JY8QFUQ01BU9D0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggcccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15020 JY8QFUQ01AD2B5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15021 JY8QFUQ01AWSRO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ2*01 F 211 88.68 47/53 nt Homsap IGHD4-23*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARFHDYGGYGFYYYSDFW in-frame + ctctggtggctccatcagtagtcattactggagctggatccggcagcccccaggggagggactggagtggattggctatatctctgacagtggaagcaccaattacaacccctccctcaagagtcgagtcactatatcagtagacacgtccgagaggcagatctccctgaagctgacctctgtgaccgctgcggacacggccgtatattactgtgcgagattccatgactacggaggttacgggttttactattactccgatttctggggccgtggcaccctggtcacggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 15022 JY8QFUQ01B6L95 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15023 JY8QFUQ01CBHBT productive (see comment) Homsap IGHV1-2*02 F 1002 96.73 207/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [0.17.38.11] CTRQRIGCGGDCYPGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgGgctactatctgcactgggtgcgacaggcccctggacaaggacttgactggatgggatggatcaaccctaacagtggtggcacaaactatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagtacagcctacatggagttgagcagtctgagatctgacgacacggccgtgtattattgtacgagacaacggatcggctgtggtggtgactgctacccaggggactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15024 JY8QFUQ01BJ4MK productive Homsap IGHV3-48*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVENYSDSGGSFDYW in-frame - cctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacaacctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaattactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15025 JY8QFUQ01CJN8G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcag 15026 JY8QFUQ01ACCKZ productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-7*01 F 3 8 7 15 8.7.15 [2.16.38.11] CIADLPDSAENYPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 9 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agcctctggattcacttttagtggcgcctggatgagctgggtccgccaggctccagggaagggctggagtgggttggccgtgttagaagcggtgggacaacagactaccctgcacccgtggaaggcagattcaccatctctagagatgatcgaaaaaacacgttgtatctggaaataagtagcctgaaaatcgaagacacagccgtatattactgtatcgcagatttgcccgactcggcagagaactatccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15027 JY8QFUQ01CS82O productive Homsap IGHV1-8*01 F 939 93.46 200/214 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [0.17.38.11] CARGYGYPNYYHYAMDVW in-frame + tggataccccttcgacagttatgatatcagctgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtgggaatacagcctatgcacagaagttccagggccgagtcacgatgaccagggacacctccacaagcacagcctacatggaggtgagcagcctcagatctgaggacacggccgtctattactgtgcgcgcggttatggctacccaaactactaccactacgctatggacgtctggggccaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttccc 15028 JY8QFUQ01BFV6C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGKMVSTGMDVW in-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15029 JY8QFUQ01BKD4D No results 15030 JY8QFUQ01BFADJ productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15031 JY8QFUQ01C02I8 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 987 94.55 208/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + ctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15032 JY8QFUQ01DFEU1 productive Homsap IGHV1-8*01 F 948 93.93 201/214 nt Homsap IGHJ1*01 F 188 84.62 44/52 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [0.17.38.11] CARGSLDYGGLPQHW in-frame + tggatacaccttcaccagttatgatatcaactgggtgcgacaggccgctggacaagggcttgagtggatgggatgggtgaaccctaatagtggtgccacaggctatgcacagaagttccagggcagagtcaccatgagcagggacacctccgaaagtacagcctacgtggagctgagcagcctgggatctgaggacacggccgtgtatttctgtgcgagaggctccctggactacggtggcctcccccagcactggggccagggcaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15033 JY8QFUQ01B0SGS productive (see comment) Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15034 JY8QFUQ01B7ETG No results 15035 JY8QFUQ01AZU67 productive (see comment) Homsap IGHV3-9*01 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [2.17.38.11] CVKDMGRSNWRYFHYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'T' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gcctctggattcacctttgatgattatgccatgcactgggtccggcaagttccagggaggggcctggaatgggtctcaggtatcagttggggtagtgctagtTatagcctatgcggactctgtaaaggggcgattcaccatctccagagacaacgccaggaactccctgtatctgcaagtggacagtctgagacctgaggacacggccttgtatcactgtgtaaaagatatggggagaagtaactggaggtactttcactattggggccagggaaccccggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 15036 JY8QFUQ01B0ETU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15037 JY8QFUQ01BE9N9 productive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgaaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15038 JY8QFUQ01AMLU0 No results 15039 JY8QFUQ01A9LQB No results 15040 JY8QFUQ01A0X2Q unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [2.17.38.11] CARIWDSWSGA#FDVW out-of-frame - stop codons Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15041 JY8QFUQ01DLALM unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 931 90.22 203/225 nt 89.33 201/225 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [2.17.38.11] CTSRYYDPSGYWSD#PG out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 220 to 220 in the user submitted sequence), (cause frameshift); gtctctggggtcaccttcagtgacgcctggatgacctgggtccgccaggctccagggaAaggggctggagtgggttggccgtattagaagcagagttgatggtgggacagtggactacgctgcacccgtgaaaggcagattcaccatctcaagagatgactccaaaaacacactatatctacaaatgaacagcctgaaaatcgaggacacagccatgtaCtttctgcaccagtcgatactatgatcctagcggttactggtccgacccctggggccagggaacccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 15042 JY8QFUQ01AI5BM productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggaggctggatgagcagccccaggccaagggaGctgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15043 JY8QFUQ01DBROA unproductive (see comment) Homsap IGHV3-13*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ6*02 F 215 82.26 51/62 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.17.38.11] CGPVMLC*YHLWVTXT#AMDVS out-of-frame + stop codons in FR2-IMGT at codon 46 of V-REGION: 'CAGG' (4 nucleotides at position 51 to 54 in the user submitted sequence), (cause frameshift); ctctggattcaccttcattagctacgacatgcactgggtccgccaggctaCAGGcaggaaaaggtctggagtgaatctcatctattggaatttctggtgacatatactatccaggctccgtgaagggccgattcaccatgtccagaggaaatgccaagaactccttgtatcttcaaatgaacagcctgagagccgaggacacggatgtatattgctgtggccctgtgatgttgtgttagtaccacctgtgggtgactnccactgcgctatggacgtctcgggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15044 JY8QFUQ01AWMMA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15045 JY8QFUQ01BLVPK unproductive (see comment) Homsap IGHV4-61*01 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD1-26*01 F 2 10 7 X 10.7.X [1.17.38.11] CARGGPVGPTGI*SGT# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 110 to 121 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtccggtggggcctactggaatttgatccgggactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 15046 JY8QFUQ01CII1K unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F (see comment) 762 84.83 179/211 nt 84.36 178/211 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 2 5 9 X 5.9.X [X.17.38.11] CIADTPTSSRQAFDY# out-of-frame - Low V-REGION identity (84,83% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) acccttttgacacctggatgaactgggtccgccagactccagggaaggggctggagtgggttggccgtattaaaacaaaattgagggcgagacaacagactacgcggccgccgtgagaggcagattcaccatctcaagagatgactccaaaaacacgctgtggctgcaaatgaatgacctgaagaccgacgacacaggcatatactactgtatagcggatacccccaccagtagtcgtcaagcttttgactattgggccagggagcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagtacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15047 JY8QFUQ01ADMP0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15048 JY8QFUQ01B3PL9 No results 15049 JY8QFUQ01C17PP productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15050 JY8QFUQ01BTXGE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CANWLSGTHSKFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccCaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagaaccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactgggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15051 JY8QFUQ01BMGFT productive Homsap IGHV3-7*01 F 924 91.36 201/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [2.17.38.11] CATSPFTVTTGKDAYW in-frame - agcctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15052 JY8QFUQ01B7L1I productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame - ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15053 JY8QFUQ01AV3G5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + cctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15054 JY8QFUQ01CCKMG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.37.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15055 JY8QFUQ01C9KPN productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ggcctcctggattcacCctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15056 JY8QFUQ01BGR80 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15057 JY8QFUQ01BSZGO productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKVRSYYGLDHTFDIW in-frame - atctggaataacctttagtacgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatgaagccagatggacgtgagacattttatgtggactctgtgaagggccgattcaccatctccagagacaatgccaggaactcactgtttctgcaaatggacagcctgagagccgaggacacggctgtatattactgtgcgaaagttcggagctactacggactagatcatacttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15058 JY8QFUQ01C3HAZ No results 15059 JY8QFUQ01CMYY7 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15060 JY8QFUQ01B0OGP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15061 JY8QFUQ01AREB7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 914 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtccttcaaggccagggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaagGgccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15062 JY8QFUQ01DNJF4 unproductive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 804 86.45 185/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARGGKSPRRDIIQGGDC#DALDLW out-of-frame + stop codons tggagacaccttcagtagccaagccatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggcgggatcatccctatttttgatatgacgaggtacccacagaggttcgagggcagaatcacgattaccgcggacacgtccacgaccacactttacatggaactgagcagcctgaggtctgaggacacggccgtgtatttttgtgcgagaggcgggaagagtcctcgtcgtgatattatacaggggggtgactgttgatgctcttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15063 JY8QFUQ01A672E No results 15064 JY8QFUQ01BG9T4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctgaattcacttttagtacctatgtcataagttgggtccgccaggtcccagggaaggggctggagtgggtctcaagtattgttgatggtggtgatatcacacactacgcagactccgtgaagggccggttcaccatctccagagacgaatccaagaacactgtctatctgcaaatgaacagcctgagagccgaggacacggccgtgtactactgtacgaaggtggcgagtcaagtgatcatggctacaacctactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15065 JY8QFUQ01CPRKO productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactaTtttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaactgtggtcatcgcctgcctggtccagggcttcttccccc 15066 JY8QFUQ01B6AB0 No results 15067 JY8QFUQ01BBNXY productive (see comment) Homsap IGHV4-4*07 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15068 JY8QFUQ01B6RJR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.16.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaagggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15069 JY8QFUQ01BIHY8 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 977 94.5 206/218 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD3-22*01 F 3 9 7 11 9.7.11 [1.17.38.11] CAGLLTTFGLQSW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcagtagtaactggtggacttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatggtggaaacacctactacaacccgtccctcaagagtcgagtcaccatatcactagacaagtccaagaaccaattctctctgaacctgaactctgtgaccgccgcggacacggccatatattactgtgcgggacttcttacgacttttggactgcagagctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15070 JY8QFUQ01AVJSP No results 15071 JY8QFUQ01CGWS6 No results 15072 JY8QFUQ01A5G7U unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGG# out-of-frame - ggctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15073 JY8QFUQ01A465M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15074 JY8QFUQ01CC0PM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGGSVGPPGG#FDHW out-of-frame - in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); tctctggattcaccttcagtagttactggatacactgggtccgccaagctccagggcaggggctggtgtgggtctcacgaattgatagttctgcgcgtctcatagcctacgcggactccgtgaagggacgattcaccgtctccagagacaacgccaagaacacggtgtatcttcaaatgaacagtctgagagccGgacgacacggctatttattactgtgcaagaggggggtcagtggggcctccaggtgggggtttgaccactggggccagggagccctggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15075 JY8QFUQ01CG2GA productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15076 JY8QFUQ01ACHS4 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ2*01 F 211 88.68 47/53 nt Homsap IGHD4-23*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARFHDYGGYGFYYYSDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtcattactggagctggatccggcagcCccccaggggagggactggagtggattggctatatctctgacagtggaagcaccaattacaacccctccctcaagagtcgagtcactatatcagtagacacgtccgagaggcagatctccctgaagctgacctctgtgaccgctgcggacacggccgtatattactgtgcgagattccatgactacggaggttacgggttttactattactccgatttctggggccgtggcaccctggtcacggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15077 JY8QFUQ01BYPRW No results 15078 JY8QFUQ01BPZVR No results 15079 JY8QFUQ01ANTVH productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15080 JY8QFUQ01B7MS9 unproductive Homsap IGHV3-48*03 F 846 88.02 191/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDKGWSGYGMDV## out-of-frame + ctctgggttcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15081 JY8QFUQ01ASB4Q unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 766 83.11 182/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15082 JY8QFUQ01AUXHC No results 15083 JY8QFUQ01B6NTH productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagccttcaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 15084 JY8QFUQ01B8E6T productive (see comment) Homsap IGHV1-69*04 F, or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 822 87.38 187/214 nt 86.45 185/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CAIPFSSSSAWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); tggaggcaccttcagcagctatgtcatcagctggctgcgacaggcccctggacaagggcttgagtggatGgggacatgtcattcctatGctttggtgtatctaacctcgcgcagaggttccagggcagagtcacaataaccgcggacacatccacgaccacagcctacatggaggtgaccaagctgagatctgaagacacggccgtctattattgtgccataccattcagcagctcgtcggcctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15085 JY8QFUQ01DIBVI productive Homsap IGHV3-21*04 F 483 89.26 108/121 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 X 2 10 X.2.10 [X.X.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcaactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15086 JY8QFUQ01C40TJ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 15087 JY8QFUQ01DMN6Y unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCL#GAFDIW out-of-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgtttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15088 JY8QFUQ01AKOFT productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc 15089 JY8QFUQ01AQTFU productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) gttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15090 JY8QFUQ01A6RAB No results 15091 JY8QFUQ01BN8PY productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15092 JY8QFUQ01DWXKU unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 702 82.21 171/208 nt 80.77 168/208 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.16.37.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (82,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 69 of V-REGION: 2 nucleotides (from position 107 in the user submitted sequence), (cause frameshift) tcgagtgcctccatgatcagttactattggacctggattcggcagccccaggaagggactgagtggattggggacatctattcctttggaggcaccagatacaaccgtccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15093 JY8QFUQ01DSNAP unproductive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAISSGLLLDG#YW out-of-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtgggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15094 JY8QFUQ01DPEDU unknown (see comment) Homsap IGHV3-23*05 F 97 54.81 57/104 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15095 JY8QFUQ01BJNIX productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 94 61.29 38/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); cctctggacgctccttgagaagctttggcatgcactgggtccCgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggcccaaatgggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15096 JY8QFUQ01CV2IT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDAVGLTRLFGDW in-frame + ctctggatttgtctttagtagatatgccatggcctgggtccgccaggctccagggcaggggctggagtgggtcgccagtattggcgggagtggtgataacacatactacgcggactccgtgaagggccggttcaccatctccagagacaactccaataacaaactgtttctgcaaatggacagtttgcgagccggggacacggccagatatttctgtgcgaaagatgcggtgggacttacccgactctttggtgactggggccagggaaccgtggtcagcgccgcctctgcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15097 JY8QFUQ01CLZ3J productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaggggcgtggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15098 JY8QFUQ01DPHAI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.37.11] CAKLENSSGNEDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 199 in the user submitted sequence), (cause frameshift) tctgaattaacgtttgatatatatgccatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15099 JY8QFUQ01ASOC9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-18*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARVRGYSYGYEYW in-frame + cctctggattcactctcaggagctatatcatggactgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagtaatagtgaatacatatattatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactctctctatctgcacatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagtacgtggttacagttatggctatgagtactggggccagggaaccctggtccctgtctcctcagcatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15100 JY8QFUQ01BXHCB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDGMMTFGGVIVPSRFFFDYW in-frame + ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtagcggtggaactacatattatgcagactccgtgaagggccggttcaccatttccagagacaactccaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgaaagatggaatgatgacgtttgggggagttatcgtccccagtaggttcttctttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15101 JY8QFUQ01AXM44 productive Homsap IGHV4-61*02 F (see comment) 713 80.54 178/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERGTTVGGASEFDSW in-frame + Low V-REGION identity (80,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggccccgtcattattgatggttattactggacgtggatccgtcagcccgccgggaagggactggagtgggtcggacgtgtcaccagtcgtggggagaccaattacagttcctccctcaagagtcgaatcttcatgtcagtagacacgtctaagaatcaattctccctgaggtttaattctgtgaccgccgcagacacggccctatattactgtgcgagagaacgcggtactacagttggcggggcgagcgaatttgactcctggggccagggagtgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15102 JY8QFUQ01A1RGD unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15103 JY8QFUQ01ADT1K productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15104 JY8QFUQ01C8WYY unproductive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFLLDG#YW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcttcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15105 JY8QFUQ01AGUED unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARGDGYNFGGLDY## out-of-frame - ctctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15106 JY8QFUQ01AYJVF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15107 JY8QFUQ01BR4RU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15108 JY8QFUQ01CE03L unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CVRGDYGGAPDITTT#YGLDVW out-of-frame - cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15109 JY8QFUQ01AW7T2 productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctcaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactaccttccccgaaccggtgacggtgtcgtggaactcca 15110 JY8QFUQ01AGQ07 unknown (see comment) Homsap IGHV3-74*03 F 103 53.6 67/125 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15111 JY8QFUQ01A2UEW unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 664 93.96 140/149 nt 93.29 139/149 nt 8 7 X 8.7.X [1.17.16.X] null - No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatg 15112 JY8QFUQ01CPEFH productive Homsap IGHV3-72*01 F 962 92.41 207/224 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15113 JY8QFUQ01AHKYB No results 15114 JY8QFUQ01BV8GM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDVSTRITMRVVVPALDYW in-frame - cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtgataatggtgacagcatattccacgcagactccgtgaagggccggttcaccatcaccagagacaactctaagaacatcctgtatctgcacatgaacagcctgagagccgaggactcggccgtatattactgtgcgaaggatgtttccacgcgtattactatgagagttgtggtgccagcccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15115 JY8QFUQ01C2BW5 unknown (see comment) Homsap IGHV3-69-1*02 P 1034 98.14 211/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found however the closest V is a pseudogene The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctagattcaccttcagtgagtactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattaggagtagtagtaccatatactacgcagactctatgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagacgcaatgaattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15116 JY8QFUQ01BMPU3 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*01 F 96 66.67 32/48 nt 8 8 X 8.8.X [1.16.37.11] CVSDLAGQKGF (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 166 in the user submitted sequence), (cause frameshift) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaagggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15117 JY8QFUQ01B5198 No results 15118 JY8QFUQ01AK22Q No results 15119 JY8QFUQ01CY5YI productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 81.19 177/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacaGgggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggGggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15120 JY8QFUQ01BGBOT unproductive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKARIYFSWFGELFP#FDYW out-of-frame + stop codons cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttcatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15121 JY8QFUQ01C33GJ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tctggagttcagccttcagtagctactggatgcactggGgtccgccaagctccagggaaGggggctggtttgggtctcacgtgttaatggtgatgGggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15122 JY8QFUQ01CT7JH productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15123 JY8QFUQ01CQLFX No results 15124 JY8QFUQ01C39CV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaagccaaggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaac 15125 JY8QFUQ01B1UNP No results 15126 JY8QFUQ01CHUH6 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 839 86.88 192/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame - tctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattggggatgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15127 JY8QFUQ01BNTQN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 554 72.48 158/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (72,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15128 JY8QFUQ01C8I32 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTDPRYFWGSGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtggattggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaAaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15129 JY8QFUQ01B9CM1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARDRSGYSSFDYW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagatagaagtggttattcgagctttgactactggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15130 JY8QFUQ01BDTPB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 741 83.18 178/214 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BDTPB ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15131 JY8QFUQ01CL0E6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15132 JY8QFUQ01AYZZX productive Homsap IGHV3-11*01 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDRGKSGSYGLDYW in-frame + tctggattcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacatcagtagtagtggtgataccatatattacgcagactctgtgaagggccgattcaccatctccagggtcaacgcccagaactcactgtctctgcaaatgaacagcctgagagtcgacgacacggccgtgtattactgtgcgaaagatcgggggaaaagtgggagctatgggcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15133 JY8QFUQ01AVSZQ No results 15134 JY8QFUQ01BGEDN No results 15135 JY8QFUQ01BU28T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 63 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtgaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15136 JY8QFUQ01A5JQQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggAagtgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctggggctgcctggtcaagggactacttgcccccgaaccggtgacggtgtcgtggaaactc 15137 JY8QFUQ01BDC8O unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15138 JY8QFUQ01CBIA5 No results 15139 JY8QFUQ01DG2ZP productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15140 JY8QFUQ01DFE49 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 15141 JY8QFUQ01DTXBK No results 15142 JY8QFUQ01C583H productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15143 JY8QFUQ01C6ZD1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgagcagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15144 JY8QFUQ01AUVO3 No results 15145 JY8QFUQ01AR9ZY No results 15146 JY8QFUQ01BT0UP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15147 JY8QFUQ01ADXNM productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15148 JY8QFUQ01AVMZN productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 712 80.82 177/219 nt 79.0 173/219 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [3.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); gtagtctctgggttcaccatcagtCacgtactccatgggcCtgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgGcagactccgtgaGgggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15149 JY8QFUQ01CDX4C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKLGVAATTWNFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); ccgtctggattcacctttaccacctatgccatgagctgggtccGgccaggctccagggaaggggctggaatgggtctcaactattagtggtagcggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15150 JY8QFUQ01BG9X3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15151 JY8QFUQ01CWFBZ No results 15152 JY8QFUQ01CR05V No results 15153 JY8QFUQ01BWOWC unproductive (see comment) Homsap IGHV3-9*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons gcctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 15154 JY8QFUQ01DBALT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - cagcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15155 JY8QFUQ01DRZ7T productive (see comment) Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15156 JY8QFUQ01BUJ4F productive (see comment) Homsap IGHV3-66*02 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD6-19*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAAVGVGSAVSFQYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttattacggtgGgaaccacatattacgctgactccgtgaagggccgattcaccatctctagagacacctccaagaacacgttatttcttcaaatgaataccctaagaggtgaggacacggctgtgtactactgtgcggcagtcggagtgggaagtgcagtctccttccaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15157 JY8QFUQ01CPGWQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15158 JY8QFUQ01BUZU5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 15159 JY8QFUQ01APXBV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactggatccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15160 JY8QFUQ01CNB3H No results 15161 JY8QFUQ01CZ23L unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.67 198/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15162 JY8QFUQ01CEEQK productive (see comment) Homsap IGHV1-2*02 F 795 85.98 184/214 nt 85.51 183/214 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-16*02 F 2 8 8 15 8.8.15 [0.17.38.11] CARHYCDTNGVCDFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tggatacagcttcaccgacttttCatattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaaatggcggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggaaatgagcaggctgagatctgacgacacggccatttattactgtgcgagacattattgtgacaccaacggcgtctgtgattttgatatctggggccaggggacaaaggtcatcgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 15163 JY8QFUQ01CL2ZL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + cctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15164 JY8QFUQ01BY1VQ No results 15165 JY8QFUQ01BH1QX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame + ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgcagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15166 JY8QFUQ01B9C4B productive Homsap IGHV3-66*02 F 898 91.55 195/213 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVGATVAFQYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) tctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtgggagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15167 JY8QFUQ01B2FOY productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD5-12*01 F 2 8 7 12 8.7.12 [2.17.38.11] CARSGLRGYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttactacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagatctgggctacggggctactactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15168 JY8QFUQ01DH9XO unknown (see comment) Homsap IGHV3-7*01 F (see comment) 756 82.95 180/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15169 JY8QFUQ01A8RE4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-12*01 F 2 7 8 12 7.8.12 [1.17.38.11] CGKQLGPIKGLTTG in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) ctctggattcaccttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacGaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattggggcccataaaggggctgactactggggccagggggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15170 JY8QFUQ01BNBBX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 992 94.57 209/221 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cagcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15171 JY8QFUQ01BY3HN productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame + cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 15172 JY8QFUQ01AT5L5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15173 JY8QFUQ01CYPQ3 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15174 JY8QFUQ01ARSJK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15175 JY8QFUQ01DMG2N No results 15176 JY8QFUQ01BGQRX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15177 JY8QFUQ01CWYFO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 3 8 8 19 8.8.19 [1.17.38.11] CARIIPYDPRTDYYYYGMDVW in-frame + cctctggattcagcttcagtaattatatcatgacttgggtccgccaggccccagggaaggggctggagtgggtctcatctattagtggaagtagtagtaacatattctacgcagactcaatgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaataatcccgtatgacccgaggaccgactattattactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 15178 JY8QFUQ01C4MIT unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 15179 JY8QFUQ01CT7D5 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYG#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15180 JY8QFUQ01CKGY7 unproductive (see comment) Homsap IGHV3-48*03 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15181 JY8QFUQ01B6ER7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15182 JY8QFUQ01C9LNB productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgaggacgtgtcatcgcctgcctggtccagggcttcttccccca 15183 JY8QFUQ01C22YF No results 15184 JY8QFUQ01B6JCZ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 15185 JY8QFUQ01BR6MY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [2.17.38.11] CLKDHRGNYFDHW in-frame - gcctctggattcggctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtagtagcgcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatggacaggctgagagtcgaggacacggccatatattactgtctgaaagatcatagagggaactactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15186 JY8QFUQ01BZBV1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGMGTVVVTNTPLYPFDI## out-of-frame + in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaactttgacagcagtgccatgaactgggtccgccaggctccagggaaggggctggagtGgggtctcagccattagtggtcgtgctttcggcacagactacgcagcctctgtgaagggccggttcaccatctccagagacaattccaagaacactctgtatctgcaaatgaacagcctgcgagtcgaggactcggccatatattactgtgcgaaaggcatggggacagtggtggtcactaatactccgttgtatccttttgatatctgggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcatctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15187 JY8QFUQ01ASXGB No results 15188 JY8QFUQ01C8H70 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 181 59.12 81/137 nt 8 7 X 8.7.X [1.17.12.X] null + No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctcggtccagggcttcttcccccga 15189 JY8QFUQ01BRZIH productive (see comment) Homsap IGHV3-48*02 F (see comment) 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [2.17.38.11] FVTERGGGLLRYLDLW in-frame - Potentially, because of detected insertion/deletion Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccagggaaggGggctggagtggatttcatatattagtagcagtagtcaaacgatttactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgcgagacgacgacacggccatttactactttgtgacagagaggggcgggggcctattacgatatttggacttatggggcctgggaactcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15190 JY8QFUQ01C29TB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15191 JY8QFUQ01CFRB3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15192 JY8QFUQ01B06FE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFD##W out-of-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactcactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15193 JY8QFUQ01B8S75 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15194 JY8QFUQ01BWWAL productive (see comment) Homsap IGHV1-2*02 F 1065 100.0 214/214 nt 99.53 213/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGPVGDSSGYEDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccggctactatatgcactgggtgcgacaggGcccctggacaagggcttgagtggatgggatggatcaaccctaacagtggtggcacaaactatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggagctgagcaggctgagatctgacgacacggccgtgtattactgtgcgagagggcccgtgggtgatagtagtggttatgaagactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15195 JY8QFUQ01AQSJG productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15196 JY8QFUQ01CPW4C No results 15197 JY8QFUQ01C3EAN unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 86 57.53 42/73 nt 8 X X 8.X.X [1.14.X.X] null - No rearrangement found cctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15198 JY8QFUQ01BY87O No results 15199 JY8QFUQ01CTDOZ No results 15200 JY8QFUQ01C8066 No results 15201 JY8QFUQ01B5EW6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 690 81.04 171/211 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 7 8 12 7.8.12 [X.17.38.11] CAREGGRGYDMDVW in-frame + Low V-REGION identity (81,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ccctggattcaacaaatatggcatgagttgggtccgtcaggctccgggggagggtctaaagtgggtctcaactattagtgatagtactggtcgcacatactactcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15202 JY8QFUQ01CZ173 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'T' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatctTtttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccc 15203 JY8QFUQ01A7O03 productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15204 JY8QFUQ01B57IR productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - tggatacaccttcaccgactacttcatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15205 JY8QFUQ01A9SL2 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 15206 JY8QFUQ01CM97F productive (see comment) Homsap IGHV3-7*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSAFFSTGHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) ctctagattcacctttaggacatattggatgagttggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15207 JY8QFUQ01A6E51 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15208 JY8QFUQ01AGXOC productive Homsap IGHV3-66*02 F 840 88.32 189/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-8*01 F 3 8 7 11 8.7.11 [1.17.38.11] CASHLMVYALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtggcaagtacatgagctgggtccgccaggctccagggcagggactggagtgggtctcagttatctatagtactggtagtacatactacgcagattccgtgaaagggcggttcaccatctccagagacagttccaacaacactctatatcttcaaatttacggcctgagagctgacgacacggctacttactactgtgcgagtcacttaatggtgtatgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15209 JY8QFUQ01CPJ56 productive Homsap IGHV3-9*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame - cctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15210 JY8QFUQ01DP0IL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARRTITAAGRGDDYW in-frame + cctctgaattcacctttagcagttttgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagcattggtactagtgttgttaacacatggtacgcagactcagtgaagggccggttcgccatttccagagacaattccaagagcacgctgtatttgcaaatgaatagcctgagagtcgaggacacggccgtatattactgtgcgaggaggacaataacagcagctggccgtggggatgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 15211 JY8QFUQ01BFD9Q No results 15212 JY8QFUQ01BFHGQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 615 92.96 132/142 nt 92.25 131/142 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 10 7.1.10 [1.X.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01BFHGQ ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift) ctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15213 JY8QFUQ01BEMSM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15214 JY8QFUQ01DNMQD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CVRDLNWSFDSW in-frame - Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cgtctgggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15215 JY8QFUQ01ASOIS productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15216 JY8QFUQ01DABC5 No results 15217 JY8QFUQ01BRBCB productive Homsap IGHV3-33*04 F (see comment) 388 78.29 101/129 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 1 X 5 14 X.5.14 [X.X.38.11] CARDAGNTWPNYFDHW in-frame + Low V-REGION identity (78,29% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttttcaattatgactccgtgaagggccgattcgccatctccagagacgattcgagggacacactgtatctccaaatgagcagcctgagagccgaggactcggccctctattattgtgcccgagatgcgggcaacacctggcccaactactttgaccactggggccagggaaccctggtcaccgtctcctcgggtgagtcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15218 JY8QFUQ01B8WMX No results 15219 JY8QFUQ01CA97H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 89.45 195/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [2.16.38.11] CAKNRGSAMADWYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'ACT' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) gcctctggattcgactttagcggctttgccatgagctgggtccgccaggcccagggaaggggctggagtgggtctcaactattACTaatggtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttaGtttctgtgcgaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15220 JY8QFUQ01C3A2G unproductive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARASTFYYDGSGYRD#FDIW out-of-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccactcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 15221 JY8QFUQ01B4VQ8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15222 JY8QFUQ01BEV2V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 930 91.03 203/223 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [3.17.38.11] CAHGPSAAPHYYYYYGLEAW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ccaggcctctggattcacctttaccaactatggcatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagatattagcgctggtggcgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaatttcaggaacacgctgtatctgcaaatgagcagcctgagagccgaggacacggccctttattactgtgcgcatgggcccagtgcagcaccccattactactactattacggtttggaagcttggggccaagggaccaaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15223 JY8QFUQ01A4SGO productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15224 JY8QFUQ01COK28 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15225 JY8QFUQ01BME4I unproductive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-9*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREPQSKCL##YFDHW out-of-frame + stop codons tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 15226 JY8QFUQ01CPB4J productive (see comment) Homsap IGHV3-13*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 146 to 146 in the user submitted sequence), (cause frameshift); agcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagaGgaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15227 JY8QFUQ01BJAEF productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15228 JY8QFUQ01A6G2Q unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 943 93.9 200/213 nt 92.96 198/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcacctttagcagccatTcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15229 JY8QFUQ01CC3ZN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15230 JY8QFUQ01A9RJ4 No results 15231 JY8QFUQ01BYAYM productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag 15232 JY8QFUQ01B9EU8 No results 15233 JY8QFUQ01AG8ZX No results 15234 JY8QFUQ01DVIS9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.16.38.11] CAKDQSCIVGPCGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) ctccgaatttcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccacgggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15235 JY8QFUQ01B50LW productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15236 JY8QFUQ01B943U No results 15237 JY8QFUQ01BV21U No results 15238 JY8QFUQ01B5851 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 106 52.86 74/140 nt 10 9 X 10.9.X [1.17.9.X] null + No rearrangement found stop codons tctccggggacagtgtctctagcagcagtgttgtttggaactggataaggcagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15239 JY8QFUQ01CRQV8 productive Homsap IGHV3-11*04 F (see comment) 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CRQV8 ; 8 AA in Homsap_IGHV3-11*04) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15240 JY8QFUQ01CPVTY unknown (see comment) Homsap IGHV4-61*02 F (see comment) 513 74.6 141/189 nt 10 7 X 10.7.X [2.17.26.X] null + No rearrangement found Low V-REGION identity (74,60% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctgggtgactccattaccagtggtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctc 15241 JY8QFUQ01AZIQK unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); ctgattcagcttcagtacctaGtaacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15242 JY8QFUQ01BOM0B No results 15243 JY8QFUQ01BXHXL unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15244 JY8QFUQ01B0Q3Z unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15245 JY8QFUQ01CPANT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDRLTISALDY## out-of-frame - ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagaccccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15246 JY8QFUQ01A81TA productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaagGgccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15247 JY8QFUQ01CI7Q0 No results 15248 JY8QFUQ01BUUH0 unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15249 JY8QFUQ01ATXE4 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaGgggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 15250 JY8QFUQ01BUYJC No results 15251 JY8QFUQ01BZ3BX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15252 JY8QFUQ01CH5S0 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtGcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15253 JY8QFUQ01BNEO3 productive Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDYGDYVAYFDYW in-frame + ctctggattcaccttcagtgcctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacgtaaagcaagttggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagattacggtgactacgtagcctactttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctacctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15254 JY8QFUQ01BXWUH unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 111 53.79 71/132 nt 8 7 X 8.7.X [0.17.11.X] null - No rearrangement found stop codons ctggattcaccttcagtaactatagcatgaactgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15255 JY8QFUQ01BAX70 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 7 8 14 7.8.14 [2.16.38.11] CARVRGYYGGQYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) gcctctggattcaccttagtagttattggatgacctggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15256 JY8QFUQ01C27TU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaAaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15257 JY8QFUQ01DXGAJ No results 15258 JY8QFUQ01CX04C unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 883 89.5 196/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKDRTLHTPAQMFYYGMDA## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggatttaccttcagttcttatagtgtcaactgggtccgccaggctccagggaagggcctggagtgggtctcatatattgataatagtggttctaccatatattatgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaactcactgtttctgcaaatgaacagcctgcgagccgaggacacggccgtttattactgtgcgaaagatcggacactacacacacccgctcagatgttttattatggtatggacgcctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15259 JY8QFUQ01AWR1D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame + cctctggattcagatttagcagctatgccatgagctgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15260 JY8QFUQ01DF3V7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcaGtctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15261 JY8QFUQ01BM98F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15262 JY8QFUQ01A4MRV productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ggctctggattcagcttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaTggggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15263 JY8QFUQ01AISGC No results 15264 JY8QFUQ01B8XS4 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 170 58.65 78/133 nt 8 6 X 8.6.X [1.17.11.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15265 JY8QFUQ01A1YN6 productive Homsap IGHV3-48*02 F 1026 97.24 211/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD1-1*01 F 2 8 8 20 8.8.20 [1.17.38.11] CASGERKDYEVRRDYYHGMDVW in-frame - ctctggactcaccttcagcagctatagtatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15266 JY8QFUQ01BRHJ6 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame + ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15267 JY8QFUQ01AOXB2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 757 83.11 182/219 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARTPCSGGNCYLRGHDLW in-frame - Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcgggtatttattattgtgcgcggacgccttgcagtggtggaaattgttaccttagaggccacgacctctggggccagggaacccaggtctccgtttccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15268 JY8QFUQ01CGJC3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15269 JY8QFUQ01AIAO1 No results 15270 JY8QFUQ01A1VJ5 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKITPPYDRSGPLY#DYW out-of-frame + cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattcccagaacacactgtatctgcaagtgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaataacccccccttatgacaggagtggtccattataccgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15271 JY8QFUQ01DW4KI productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 96.89 218/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 152 to 152 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcAttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacCccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15272 JY8QFUQ01AJQ24 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CASLNTHSGPGAERSAFDIW in-frame + ctctggatttaccttcagtctctatagaatgaactgggtccgccaggctccagggaagggactggagtgggtctcatccattactagtaccagtagttacatttattatgcagacccagtgaagggccgattcaccatctccagagacaacgccaagaactcattatatctccatatgaacagcctgagagtcgaggacacggctatatattattgtgcgagtctgaacacgcactcgggaccgggggccgaaaggtctgcttttgatatctggggccacgggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 15273 JY8QFUQ01BPEQB productive (see comment) Homsap IGHV3-7*01 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARRGTQLGYCASPSCPTDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'TT' (2 nucleotides at position 84 to 85 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagGctactggatgcactgggtccgccaggctccagggagggggctggagtgggtggccagcatTTaaggcagacgggaactgagaagacgtttggggactctgtgaagggccgattctccatctccagagacaacgccaggaactcagtggatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcgaggaggggaacacaactgggatactgtgctagccctagctgcccaactgacttgtggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15274 JY8QFUQ01AU6XD unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 792 85.25 185/217 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [2.17.38.11] CAREFRAPSVGRYGMDV## out-of-frame - gcctcgggggttcagcgtcaataataacttcatgacttggttccgccaggttccagggaaggggctggagtgggtctcagttatctatacaaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccgagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtactactgtgcgagagaatttcgggcgccttctgtgggcagatatggtatggatgtctgggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15275 JY8QFUQ01CWFLX productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15276 JY8QFUQ01BZ43M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame - ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15277 JY8QFUQ01BJQ34 No results 15278 JY8QFUQ01CR1WB productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 897 91.94 194/211 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [0.17.38.11] CTRELRLAAARDGVDIW in-frame - tgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15279 JY8QFUQ01C422J No results 15280 JY8QFUQ01COIPL productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + tctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15281 JY8QFUQ01CVCST productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - gcctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15282 JY8QFUQ01B6LR9 unproductive Homsap IGHV1-8*01 F 921 92.52 198/214 nt Homsap IGHJ1*01 F (see comment) 102 65.38 34/52 nt Homsap IGHD1-7*01 F 2 8 8 X 8.8.X [0.17.38.11] CARARGVESSGIYVYHFD#S out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcaccacttatgacatcaactgggtgcgacaggccgccggacaagggcttgagtggatgggatgggtgaaccctgtcactggtaacacaggctatatacagaagttccagggcagagtcaccatgaccatgagcacctccacaagcacagcctacatggagctgagcagcctgaaatctgacgacacggccgtgtattattgtgcgagagcccggggggtagaaagttcggggatctacgtgtatcactttgactctcgggccagggaacctggtgnaccgtctcctcagcatcccgacccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15283 JY8QFUQ01CUNY6 No results 15284 JY8QFUQ01BY866 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 962 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ctctgggtggctccatcagGtagttactactggagctggatccggcagcccccaggaaAagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15285 JY8QFUQ01BBVBY unproductive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15286 JY8QFUQ01B1UE8 productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15287 JY8QFUQ01AHC5C No results 15288 JY8QFUQ01DMD7I No results 15289 JY8QFUQ01C8WAN No results 15290 JY8QFUQ01AFU1T unproductive Homsap IGHV3-7*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CARWRGQQSEMEY## out-of-frame - gcctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15291 JY8QFUQ01C94YX unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 765 83.41 181/217 nt 82.49 179/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.37.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 191 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtggggggTccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15292 JY8QFUQ01BZSGP productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 91.24 198/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'G' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatGggggatcatctatcctggtacctctgagaCccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaagGgccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15293 JY8QFUQ01AOAL3 productive (see comment) Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaGggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15294 JY8QFUQ01A93ME unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 844 86.94 193/222 nt 86.49 192/222 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-18*01 F 3 8 10 X 8.10.X [1.16.38.11] CTWGQHWLFSAY#W out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaagggctggagtgggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctggggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15295 JY8QFUQ01CTGXO productive (see comment) Homsap IGHV3-7*01 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); agcctctacattcacgtttagtcggtattggatgagctgggtAccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15296 JY8QFUQ01AA0G1 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15297 JY8QFUQ01CZZJY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [0.17.38.11] CANGGVVT#DLDYW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaacgggggggtggtaacggcgaccttgactactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15298 JY8QFUQ01C00M2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15299 JY8QFUQ01BDZ68 No results 15300 JY8QFUQ01CROXD No results 15301 JY8QFUQ01BYT5N productive Homsap IGHV3-7*02 F 866 90.09 191/212 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [X.17.38.11] CARDQVTEDYW in-frame - ggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15302 JY8QFUQ01CIAOZ No results 15303 JY8QFUQ01BU5OB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15304 JY8QFUQ01CIG7L productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15305 JY8QFUQ01C9708 unproductive Homsap IGHV3-11*01 F 942 92.27 203/220 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [2.17.38.11] CVRYWGSYYYYNGLDV## out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) gcctctgggattcaccttcactgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtggtggtagaaccattgcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatattggggcagctactattactataacggtctggacgtctggggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15306 JY8QFUQ01BN8PD unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - stop codons cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgagtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15307 JY8QFUQ01DGL72 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15308 JY8QFUQ01DM60H productive (see comment) Homsap IGHV3-48*02 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKDRGGSAYPIFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtgggAtttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15309 JY8QFUQ01BBH3B productive (see comment) Homsap IGHV3-74*03 F (see comment) 682 78.83 175/222 nt 78.38 174/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [3.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,83% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); gcctctggaattcacgtttccacacctcctggatggcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15310 JY8QFUQ01BU6HU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15311 JY8QFUQ01CIVAZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 15312 JY8QFUQ01DBTJ6 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 2 8 8 10 8.8.10 [1.17.38.11] CVKDLLGGDPFW in-frame - cctctggattcaccttcagtcgctatggcttgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcagatgatgggaagaataaattctatacagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgatgtttgtgcaactgaacagtctgagagctgaggacacggctgtgtattactgtgtgaaagacctactaggtggtgaccccttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15313 JY8QFUQ01BLHAL productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 980 95.35 205/215 nt 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtcattacCtggagctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 15314 JY8QFUQ01AWFBK unproductive Homsap IGHV3-9*01 F 918 91.71 199/217 nt Homsap IGHJ6*01 F (see comment) 108 63.49 40/63 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFEY# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtgacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagcccggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 15315 JY8QFUQ01CII5W productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 773 84.65 182/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARERGSGPPTGMDVW in-frame + Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaagaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15316 JY8QFUQ01CQ28T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtagtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15317 JY8QFUQ01BXV0U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15318 JY8QFUQ01DRZIH productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccaCtttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15319 JY8QFUQ01DWRUR unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 863 87.05 195/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 10 X 8.10.X [1.17.38.11] CTADVPVTISAK#DFW out-of-frame + cctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagagaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccagtcaccattagcgcaaaattgacttctggggccagggaaccctggtcaccgtctcctcagnatccccggaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15320 JY8QFUQ01ATZED productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15321 JY8QFUQ01B1EK1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1043 98.6 212/215 nt 97.67 210/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.16.37.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 90 of V-REGION: 1 nucleotides (from position 174 in the user submitted sequence), (cause frameshift) ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15322 JY8QFUQ01CWOBR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKDGGDTYGYARYW in-frame + ctctggattcaagtttgatgattccggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctcaacaatttttgccagtggtgttaccacatattacgcagactccgtgaagggccgattcaccatctccagagacaattccaataatagagtgtttctgcaaatgaccagcctgagagacgaagacacggccgtatactactgtgcgaaagatggtggagacacatatggttacgctcgctactggggccagggaagtctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatcctggtccagggcttcttccccca 15323 JY8QFUQ01AX6F4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15324 JY8QFUQ01C0DZ4 productive (see comment) Homsap IGHV4-4*07 F 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 7 11 8.7.11 [1.17.37.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGCAC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgtcgccaccagtagTGGCACttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaaccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15325 JY8QFUQ01CYI7D productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15326 JY8QFUQ01DP020 No results 15327 JY8QFUQ01AS8FY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctgggattcagcttaagttcttatggcatgaactgggtccgccaggctccaTgggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15328 JY8QFUQ01B3M9E No results 15329 JY8QFUQ01ADQQX unknown (see comment) Homsap IGHV3-48*03 F 873 89.4 194/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15330 JY8QFUQ01AW02O productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + ctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttc 15331 JY8QFUQ01ARANR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctctggattcaccttcaggaactattggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15332 JY8QFUQ01B3GAT No results 15333 JY8QFUQ01AJYIB productive Homsap IGHV3-7*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - tgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15334 JY8QFUQ01BH4WY No results 15335 JY8QFUQ01BNTRC No results 15336 JY8QFUQ01ATI4C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1058 98.17 214/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 15337 JY8QFUQ01A5XL0 productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15338 JY8QFUQ01AWR2C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15339 JY8QFUQ01CBZAC productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 856 88.13 193/219 nt 86.76 190/219 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [2.17.38.11] CTRVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); gcctctggattcaactttgcagattatggcttggGgctgggtccgccaacttccagggGAagggggctggaatgggtcggtggtgttaattggaatgGggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 15340 JY8QFUQ01ALW0Z productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15341 JY8QFUQ01BL77H productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame + ctctggattcaccgtcagtaccaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgatggtcgtgcgcatgcctggctccagggcttcttccccca 15342 JY8QFUQ01DJJA2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15343 JY8QFUQ01AJXYH unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 120 57.14 60/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggagcgtggtcatcgcctgcctggtccagggcttcttccccca 15344 JY8QFUQ01COOK2 No results 15345 JY8QFUQ01BRJW5 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 289 65.16 101/155 nt 8 8 X 8.8.X [1.17.17.X] null - No rearrangement found Low V-REGION identity (65,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15346 JY8QFUQ01CCKLV productive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-2*01 F 3 8 7 19 8.7.19 [1.17.38.11] CVRDGGVIVVVPMDYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 2 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) ctctggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatagcgagatggaactgagagtcattatgtggactctgtgaagggccgattcatcatctccagagacaactccaggaatttactgtatctccaaatgaacagcctgagagtcgaagacacggctgtgtattattgtgtgagagatgggggtgttattgtagtagtgccaatggactattacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15347 JY8QFUQ01A1409 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.37.11] CVSDLAGQKGF# out-of-frame + in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15348 JY8QFUQ01CYVB4 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARPHHNSGYSFDHW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) gtctgatttcaacgtcggtgactttgacatgcactgggtccgccagactccagacaaggggctggagtgggtggcactttttggtatgacggaaagaggaaatattatgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatggacagcctgagagccgacgacacggctacctacttttgtgcgaggcctcatcataatagtggttattcctttgaccactggggccagggaacccaggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15349 JY8QFUQ01A8IF7 No results 15350 JY8QFUQ01DQDY7 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 95.85 208/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD7-27*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGANWGPGP#FDYW out-of-frame + ctctggattcactttcagtagaaactggatgaactgggtccgccaagctccagggaaggggctggtntgggtctcacgtattagtagtgatgggagtagcacaacctacgcggactccgtgaagggccgattcaccatctacagagacaacgccaagaacacgctgtatgtgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaggggccaactggggaccgggcccccttttgactactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15351 JY8QFUQ01C6QNV unproductive (see comment) Homsap IGHV3-7*03 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [2.17.38.11] CANWLSGTHSKFDYW in-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'AC' (2 nucleotides at position 23 to 24 in the user submitted sequence), (cause frameshift); gcctctggatttagcatttagaACccttttggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15352 JY8QFUQ01BF71M No results 15353 JY8QFUQ01DWIC5 unproductive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 591 95.38 124/130 nt 94.62 123/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-25*01 F 1 8 X X 8.X.X [1.3.31.11] CAKGGW*R##LDYW out-of-frame + stop codons in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggatggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 15354 JY8QFUQ01CI6DV unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 15355 JY8QFUQ01A3MV4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15356 JY8QFUQ01BX5EZ unproductive Homsap IGHV3-11*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CADIRLGDWCFDI# out-of-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctgggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15357 JY8QFUQ01BW9DT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15358 JY8QFUQ01DQMRU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 957 94.39 202/214 nt 93.46 200/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccggggaaAAagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15359 JY8QFUQ01ACSEL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15360 JY8QFUQ01B0KVC unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 927 92.17 200/217 nt Homsap IGHJ4*03 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARVGGTEEFAGMLELDY## out-of-frame + gtctggattcagtttcagtagctttggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatctggtatgatggaactaataaatattatgcagactccgtgaagggccgattcaccatctcgagagacaattccaagaacacactgtttctgctcatggacagcctgacagccgacgacacggctgtctattactgtgcgagagtcgggggaaccgaggagttcgctggtatgttggaacttgactactgggggccaggggaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 15361 JY8QFUQ01CCIFV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 189 to 189 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgaGgctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgGagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15362 JY8QFUQ01BAS63 No results 15363 JY8QFUQ01AOUQ1 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD3-22*01 F 3 7 8 X 7.8.X [1.17.38.11] CARHSHSSGYSSLDALEI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 93 of V-REGION: 'C' (1 nucleotides at position 182 to 182 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) ttctgcatatagttttccagttactggatcgcctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatcaatcccggtgactctgataccagatatagcccgtcctttcaaggccaggtcaccgtctcagccgacaggtccatcagtaccgcctacctgcagtggaaaaCgcctgagggcctcggacaccgccatgtattactgtgcgcgacactcccacagtagtggttattccagccttgacgctcttgagatctggggcccaagggacaatggtcaccgtctcttctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15364 JY8QFUQ01AK1U1 unknown (see comment) Homsap IGHV1-2*01 F 164 55.42 92/166 nt 7 8 X 7.8.X [X.17.23.X] null - No rearrangement found atacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcagccccaaggtcttcccgcctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15365 JY8QFUQ01ATAHA unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaaatgggactactggggggacagggggaacccctggtcaccgtctccctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15366 JY8QFUQ01AVMUI No results 15367 JY8QFUQ01B2NEX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 15368 JY8QFUQ01B6LQX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGLGSYLYCFDYW in-frame + ctctggattcccctttatcagctatgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggtttggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtctagggcttcttccccca 15369 JY8QFUQ01BHYPA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYFYYFDYW in-frame + cctctggattcacctttagccactatgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagtggtagtgatggtagcacgtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagaagtatcactatggttcggggacttacttctactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15370 JY8QFUQ01AG87O productive (see comment) Homsap IGHV4-61*02 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagtggtacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 15371 JY8QFUQ01AU60E productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 15372 JY8QFUQ01APAT3 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 87 90.48 19/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattaaccctcagtga 15373 JY8QFUQ01DVDDQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CAKDLVVTSIGPQGIHGH## out-of-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15374 JY8QFUQ01CQ6E4 productive Homsap IGHV3-9*01 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CVKDRKGSNWYYFENW in-frame - cagcctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15375 JY8QFUQ01BKTS0 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 996 95.0 209/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 3 9 9 19 9.9.19 [X.17.38.11] CARSSRRDRLSDRNYYELDFW in-frame - ggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccctcaccccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattattgtgcaagatcttccagacgcgatcgtttgtctgataggaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15376 JY8QFUQ01BNC1N unknown (see comment) Homsap IGHV1-8*01 F 580 92.54 124/134 nt 8 8 X 8.8.X [0.17.11.X] null - No rearrangement found tggagacaccttcaccagttatgatatccactgggtgcgacaggcctctggacaagggcttgagtggatgggatggatgaaccctaacagtggtaacacaggctattcacagaggttccagggcttcttcccca 15377 JY8QFUQ01A4Y3T No results 15378 JY8QFUQ01C0W1R unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 3 7 7 X 7.7.X [0.17.38.11] CAKVYTGAWGIL#FDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) ctggattcagcttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtactttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctgggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15379 JY8QFUQ01ALUAS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15380 JY8QFUQ01BYTWC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 780 84.09 185/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKDTITMGGDVAPLFDYW in-frame - Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release acctctgggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15381 JY8QFUQ01AKVV1 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATLPSPGARRPFDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ttctggatacagttttgccgactattggatcggctgggtgcgccagaggcccgggaAaaggcctggagtgcatgggggtcatctatcctggtgactctgatgtcagatacagcccgtccttccggggccaggtcaccatctcagccgacaagtccatcagcactgcctacctgcagtggagcagcctgaaggcctcggacaccgccttgtatttttgtgcgacccttccctcgcccggggcccgaagaccctttgaccactggggccagggaacccgagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15382 JY8QFUQ01B4YS0 productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15383 JY8QFUQ01CJO9P No results 15384 JY8QFUQ01B56KK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15385 JY8QFUQ01AMI2A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctggcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15386 JY8QFUQ01ANXW0 No results 15387 JY8QFUQ01A8XOR productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGVFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggtttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15388 JY8QFUQ01BU5BA productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 669 79.44 170/214 nt 78.04 167/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggGatatatgttggagactccgtgaagggccgcttcaccgGtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacataCtttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15389 JY8QFUQ01AO1TQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagacttcgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15390 JY8QFUQ01C7O3L No results 15391 JY8QFUQ01BTK8S unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 93.72 209/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTGGWN*L##W out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 200 to 200 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaaGtatgctgtatctgcaattgaacagcctgaaaacCcgaggacacagccgtgtatttctgtaccacagggggttggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15392 JY8QFUQ01CV1TO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CAKQTIFDYYYYGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); agcctctggattcacctttatcaactatgGgcatgagctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15393 JY8QFUQ01AYCCC productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15394 JY8QFUQ01B8PFU productive (see comment) Homsap IGHV4-31*06 F (see comment) 740 81.82 180/220 nt 81.36 179/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tctcgggtggttccatgacgagtactaAttttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15395 JY8QFUQ01BNK9R No results 15396 JY8QFUQ01BJ5NY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagtacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15397 JY8QFUQ01A3ZKS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15398 JY8QFUQ01DDXP7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.12 203/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGAQLLCQ*WA*LL# out-of-frame - stop codons cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggantgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagaggggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15399 JY8QFUQ01ATTGD unproductive Homsap IGHV3-9*01 F 1026 97.24 211/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDMGYTWKYIDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattattgtgcaaaagatatggggtatacctggaagtacattgaccactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15400 JY8QFUQ01AYNMV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15401 JY8QFUQ01AP0IP productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15402 JY8QFUQ01DV9LQ productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaagggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15403 JY8QFUQ01CHTJ1 unproductive Homsap IGHV4-61*02 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGSGSGSYSNL## out-of-frame - in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagGcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggccccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacggcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15404 JY8QFUQ01CQ2B9 unproductive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARVGGNRGVRWYVG##DYW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagtcggggggaaccgaggagttcgctggtatgttggaacttgactactggggccaggggaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15405 JY8QFUQ01DMHZC productive Homsap IGHV3-48*01 F 1005 95.45 210/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - agcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15406 JY8QFUQ01A8JNE productive Homsap IGHV2-5*02 F 1022 91.02 223/245 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 18 10.7.18 [9.17.38.11] CAHNSLYDRNGYYLTYFDHW in-frame + agaccctcacactgacctgcaacctctctggggtctcactcagcagtcgtggagtgggtgtgggctggatccgtcaggccccaggaaaggccctggagtggcttgccctcattgattgggatgatgacaagcgctatagtccatctctaaaggggaggctcaccatcaccagggacacctccacaggccaggtggtcttcacaatgaccaacatgcaccctgtggacacagccacatattactgtgcacacaacagtctctatgataggaatggctattatttgacgtactttgatcactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 15407 JY8QFUQ01CJVYW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [2.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15408 JY8QFUQ01BFP4R unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [0.17.38.11] CASFRVLESGY## out-of-frame - ctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15409 JY8QFUQ01ANW4L No results 15410 JY8QFUQ01BM8SJ unknown (see comment) Homsap IGHV3-69-1*02 P 1029 98.13 210/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found however the closest V is a pseudogene The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcaccttcagtgagtactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattaggagtagtagtaccatatactacgcagactctatgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagacgcaatgaattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15411 JY8QFUQ01BO7ET No results 15412 JY8QFUQ01BXGYG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtatcttcggactcgtctgggcccgtggcaccctggtcactgctctcctcagcctccaccaaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15413 JY8QFUQ01CPBJI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYYYHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcaactatgccatgagctgggtccgccaggctccagggaAaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagattccgtgaggggccggttcaccatctccagagacaattccaagaacactctgcatctgcatatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaagtatcactatggttcggggacttattattaccacttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15414 JY8QFUQ01BCUID productive Homsap IGHV3-48*04 F 1005 95.45 210/220 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CARDAGGSGWYLYYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) agcctctggattcaccttcagtagttataccatgcactgggtccgccaggctccagggaaggggctggaatgggtctcatccattagtagtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacggcctgagagccgaggacacggctgtttattcctgtgcgagagatgcggggggcagtggctggtacctttactactttgactcctggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15415 JY8QFUQ01AE4IG productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15416 JY8QFUQ01ALUYN No results 15417 JY8QFUQ01APVC5 productive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-74*03 F (see comment) 393 78.46 102/130 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 X 5 17 X.5.17 [X.X.38.11] CVRDSGPSGYARYESMDVW in-frame - Low V-REGION identity (78,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagcctcacttcctatggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagtggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15418 JY8QFUQ01BP3RA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 2 8 7 12 8.7.12 [1.17.38.11] CAVSTTTWGWFDPW in-frame - tctatggtgggtccttcagtggttactactggagctggatccgccagcccccaggggaggggctgcagtggattggaagagtcaatcatagtggaagcaccagctacaacccgtccctcaagagtcgagtcaccatgtcactagacacgtccaagacccacttttccctgaagctgacctctgtgaccgccgcggacacggctgtgtattactgtgcggtgtctactaccacctgggggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15419 JY8QFUQ01DA8PQ No results 15420 JY8QFUQ01BQ849 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15421 JY8QFUQ01B791I productive Homsap IGHV1-3*01 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGRYDSSGRGHEYW in-frame - ctggatacaccttcaccagtttcagtatccattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacggtggcaatggtaacacaaaatattcacagaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15422 JY8QFUQ01AS13H unknown (see comment) Homsap IGHV3-48*02 F (see comment) 356 62.84 137/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (62,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15423 JY8QFUQ01ALDY2 productive Homsap IGHV4-59*03 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatccggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15424 JY8QFUQ01BJHAO productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaAaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 15425 JY8QFUQ01CE696 productive Homsap IGHV3-11*01 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame + cctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 15426 JY8QFUQ01B8GRW productive Homsap IGHV3-7*03 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15427 JY8QFUQ01A2DRJ No results 15428 JY8QFUQ01AUB3V productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 15429 JY8QFUQ01C2ZU3 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 84.68 188/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtGactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15430 JY8QFUQ01ARLF9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 906 90.45 199/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ggcctcctggattcaccCtttggttattatggcatgactgggtccgccaagctccggggaagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15431 JY8QFUQ01BOD1U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 996 95.0 209/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - ggcctctggattcatcttcagtaaatataccatgaaatgggtccgccaggctccagggaaggggctggagtgggtctcatccatcagtagtagtagtggttacatatactactcagattcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15432 JY8QFUQ01C7COD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15433 JY8QFUQ01A727M No results 15434 JY8QFUQ01CPKFW productive Homsap IGHV3-72*01 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 10 9 8.10.9 [0.17.38.11] CAVAAPPYDGW in-frame - ctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagcccccccttatgacggctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15435 JY8QFUQ01AJL5M productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15436 JY8QFUQ01AK6RN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15437 JY8QFUQ01CFF9I unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 X 8.7.X [1.17.38.11] CASANYDYALGGVIV#DYW out-of-frame - tctgggtggctccatcagtagttactactggagctggatccggcagacccccaggaagggactggagtggattgggtatatctattacagtgggagcaccaacacaagcccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgctttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15438 JY8QFUQ01CQEAZ productive Homsap IGHV4-59*02 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARHSMGVTIVRGHWFDPW in-frame + tctctggtggctccgtcagcagttattactggagctggatccgacagcccccagggaagggactggagtggattggctatatccatgacagtgggagcagcaactacaacccctccctcaagagtcgagtcaccatatctgtggacacgtccaagaaccagttctccctgaagctgacttctgtgaccgctgcggacacggccgtatattactgtgcgagacattctatgggtgttactatagttcggggacactggttcgacccctggggccagggaaccctggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtggaactc 15439 JY8QFUQ01CX9AH productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 849 88.32 189/214 nt 86.45 185/214 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CGGAAG' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 31 of V-REGION: 6 nucleotides (from position 17 in the user submitted sequence), (do not cause frameshift) ctctggtggctccatcacCGGAAGtagttattattggggctggattcgccagTcccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaaccccGtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15440 JY8QFUQ01AFMHP unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 918 91.71 199/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 2 9 7 X 9.7.X [1.17.38.11] CARLTDWWG##FDHW out-of-frame + stop codons in CDR1-IMGT at codon 36 of V-REGION: 'CTT' (3 nucleotides at position 24 to 26 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 3 nucleotides (from position 20 in the user submitted sequence), (do not cause frameshift) ctctggtggctccatcagcggtaCTTctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaaccCcgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtggggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctggcctggtccagggcttcttcccc 15441 JY8QFUQ01CZKRB productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 971 94.88 204/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD5-24*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CARWAYGYNYWDLW in-frame + tctctggtggctccatcagtgattactactggacctgggtccggcagcccccagggaagggactggagtggattggatatgtcgaatacagtgggaacaccaactacaacccctccctcaggagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagatgggcctatggctacaattattgggatctctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15442 JY8QFUQ01BITUS productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 845 86.61 194/224 nt 85.27 191/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 1 8 10 14 8.10.14 [1.17.38.11] CSRARWSTTWYVFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'GC' (2 nucleotides at position 161 to 162 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); cttctggattcatgtttggtgatcatgggatgggctggttccgccaggctgcagggaagggcctggagtgggtaggcttcattGaaaactacaccttatggtgcggcaagccattacgccgcgtctgtgggaggcagattcagcatctcaagagatgattGCcaaaaagcgtcgcctatttgcaaatgagcagtctggaaaccgaggaGcacagccgtgtattattgttctcgagcgcggtggagcaccacttggtacgtctttgactactgggcccagggaacccaggtcgccgtctcctcagcctcccaccgaacgggcccatcggtccttgccccctggccaccctcctccaagagcacctgctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15443 JY8QFUQ01ALTNT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15444 JY8QFUQ01CEVLG unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15445 JY8QFUQ01DPKH6 productive Homsap IGHV3-48*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaagggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15446 JY8QFUQ01AZQKC productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15447 JY8QFUQ01BMLGO productive Homsap IGHV3-23*05 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKSTGHSGWYPFDNW in-frame + cctctggattcacattcagcaattatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtcgctgctattgatggcagtggtgaaagaactcactatgcagactccgaacagggccgcgtcaacatctctagagacaattccaagaacatgatatatgtgcaattgagcagcctgagagccgaggacacggccatgtattactgtgtgaagtccaccgggcacagtggctggtatccctttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15448 JY8QFUQ01B8C5C No results 15449 JY8QFUQ01AKXHF unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca 15450 JY8QFUQ01AQF2V No results 15451 JY8QFUQ01AQZ7P productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15452 JY8QFUQ01DH3CZ productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + ctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15453 JY8QFUQ01CMRID unproductive (see comment) Homsap IGHV3-48*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CARVEKLL**WWF#FDYW out-of-frame + stop codons ctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaagttactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 15454 JY8QFUQ01B2HM8 productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15455 JY8QFUQ01BITPA unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 83.8 181/216 nt Homsap IGHJ2*01 F (see comment) 32 63.16 12/19 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttcccgaaccggtgacggtgtcgtggaactcag 15456 JY8QFUQ01DPAMQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [0.17.38.11] CTRDIGGRYSYW in-frame - tggttacacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15457 JY8QFUQ01BC6IA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15458 JY8QFUQ01BQUG5 productive Homsap IGHV3-13*01 F 985 95.37 206/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPL in-frame + gcctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcaaatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgaccccctgggccagggaacctgtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15459 JY8QFUQ01C1155 productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F (see comment) 609 75.45 166/220 nt 75.0 165/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-13*01 F 3 8 8 15 8.8.15 [2.17.37.11] CARGQKWLQVARWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (75,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) aggtagtggatacgaaattcgacgactatagtatgcactgggtccgcctagtcccagggacgggtctgcagtggattgcatacattagtcctaccagcagttccaagtactatgcggactctgtgaagggccgattcatcgtctcccgagacaacgccaagaaattacttttctgcaaatgaccaacctgagagacgacgacacggccttctatcactgtgcgagaggtcaaaaatggctgcaggtggcccgttggttcgacccctggggccagggaaccctggtcaccgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15460 JY8QFUQ01C1O5I productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15461 JY8QFUQ01AJGZ5 No results 15462 JY8QFUQ01DH00E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKDASRYYYNSYCDNW in-frame - gcctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15463 JY8QFUQ01DN3YF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 821 85.97 190/221 nt 85.52 189/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctGggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatgagttttccctgacactgacctctatgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 15464 JY8QFUQ01ARR3V unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGRYDENYYELDF## out-of-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15465 JY8QFUQ01CC2EX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 15466 JY8QFUQ01C69IF productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 15467 JY8QFUQ01AHLSP No results 15468 JY8QFUQ01BJDZ9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 15469 JY8QFUQ01AMOSM productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 923 91.74 200/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15470 JY8QFUQ01B89WK productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1009 93.86 214/228 nt 93.42 213/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CARGSSRGERSDVNYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggagagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatcctcgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15471 JY8QFUQ01DAUPX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDASRYYYNSYCDNL# out-of-frame - in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaatttgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15472 JY8QFUQ01C2L0Q unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 133 52.43 97/185 nt 8 7 X 8.7.X [1.17.28.X] null - No rearrangement found tctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15473 JY8QFUQ01CAWNM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15474 JY8QFUQ01AWPYT unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 710 91.12 154/169 nt 8 7 X 8.7.X [1.17.22.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AWPYT ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 15475 JY8QFUQ01CNZ7K No results 15476 JY8QFUQ01A3AHC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag 15477 JY8QFUQ01DO2CA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15478 JY8QFUQ01DXFBE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*03 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CXRDSDSSGYARYDSMDVW# out-of-frame + Other possibilities: Homsap_IGHJ2*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgngagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctgggggccaaagggaccgcggtcaccgtctcatcagcctccaaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactcag 15479 JY8QFUQ01BF9JF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15480 JY8QFUQ01BFXYS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CAKTQPFGTTWYGATDAW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgagcagcctaagagccgaggacacggccttatattactgtgcaaagacgcagccgtttggcaccacctggtacggtgctacggatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15481 JY8QFUQ01BAVEX No results 15482 JY8QFUQ01CBQCV No results 15483 JY8QFUQ01AFH1F unproductive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 1 8 7 X 8.7.X [2.17.38.11] CASSVFSPRR#FDYW out-of-frame + stop codons tttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtccccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15484 JY8QFUQ01CE1X7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15485 JY8QFUQ01C5482 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 944 93.49 201/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagccCcccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaaccCcctccctcaagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15486 JY8QFUQ01AOCIF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 212 87.27 48/55 nt 8 8 10 8.8.10 [1.17.38.11] CARDRYYVVDVW in-frame - cctctggattcaccttcagtgccacctggatgcactgggtccgccaagctccagggcaggggctggtgtgggtctctcatattaatggtgatgggagtagcacaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatttgcaaatgaacagtctgagagccgaggacacggctgtatactactgtgcaagagatcgatactacgttgtggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15487 JY8QFUQ01CQST2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15488 JY8QFUQ01ALW5O productive Homsap IGHV3-11*01 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVRDGARRTNQWLAHDFW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagctttaatgccttctatatgggttgggtccgccaggctccaggaaaggggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 15489 JY8QFUQ01BJQAH productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 7 7 8 7.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctgcagcctctggattcattgtcaatagcactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15490 JY8QFUQ01B20UU productive Homsap IGHV3-48*01 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt 8 8 7 8.8.7 [0.17.38.11] CARAPFDYW in-frame - tggattcatctttagtagctatagtatgaactgggtccgccaggctccagggaaggggccggagtgggtttcatacattagcggtagtagtagctccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagccccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15491 JY8QFUQ01BWEYJ No results 15492 JY8QFUQ01AE8QV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15493 JY8QFUQ01AX9OZ unproductive (see comment) Homsap IGHV3-11*01 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CVREVTGVWDW#FDPW out-of-frame + stop codons cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggttttgacccctggggccggggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15494 JY8QFUQ01C0NN1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15495 JY8QFUQ01AT4NT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15496 JY8QFUQ01AH89D unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 88.84 191/215 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaaccCcctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaaggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 15497 JY8QFUQ01DD35D No results 15498 JY8QFUQ01DAUWI unproductive (see comment) Homsap IGHV4-61*02 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 X 10.7.X [1.17.37.11] CARDPQGYL*WW*LPLFC#MDVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaaccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccgtgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 15499 JY8QFUQ01CG66E productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15500 JY8QFUQ01BIOGL productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15501 JY8QFUQ01BQAQL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaagaggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15502 JY8QFUQ01CJKY6 No results 15503 JY8QFUQ01AEU6X productive Homsap IGHV3-11*01 F 865 88.58 194/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARDGDADYGDLPIPFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctgaattcagtttcactgaccaccacatgagctggatccgccgggctccagggaaggggctggagtgggtgtcatacattagtcctacaggtagtgccatattttacgcagactctgtgaaggcccgtttcaccatctctagggacaacgccaagaatttactatatctacaaatgaacagcctgagacccgaggacacggccatctattactgtgcgagagatggggacgcggactacggtgacttgcccatccctttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15504 JY8QFUQ01BG290 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 7 7 21 7.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) cctctggacgctccttgagaagctttggatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcagccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15505 JY8QFUQ01CNWM0 productive (see comment) Homsap IGHV4-34*10 F 791 85.58 184/215 nt 84.19 181/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tgtctggtgagtccttcactaattactactggagctggatccgccagtcccccaggaAAagggtctggagtggcttgggggAggtccatcatagtggacgcaccgactacaaccccGtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15506 JY8QFUQ01AN2OV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15507 JY8QFUQ01AQ0ZB unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame - cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15508 JY8QFUQ01BBDL1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.37.11] CVREGAATGSFYYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccaggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 15509 JY8QFUQ01CIZF1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15510 JY8QFUQ01BM11Z unproductive Homsap IGHV4-39*02 F 947 91.86 203/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 10 7 X 10.7.X [1.17.38.11] CARRYSWNYE##FDPW out-of-frame + tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaacggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15511 JY8QFUQ01CR0Q8 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15512 JY8QFUQ01A0FO5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag 15513 JY8QFUQ01DNG2W productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15514 JY8QFUQ01C5LS4 productive (see comment) Homsap IGHV4-34*10 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [2.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gtgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaAagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15515 JY8QFUQ01CLQNM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15516 JY8QFUQ01AHGEL No results 15517 JY8QFUQ01BP6JA productive Homsap IGHV3-11*06 F, or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F 165 68.35 54/79 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 X X 12 X.X.12 [X.X.26.11] CARGTSVDPGIDHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaattattggatgcactggatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15518 JY8QFUQ01CF38L unknown (see comment) Homsap IGHV3-21*04 F 851 88.07 192/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaacccgtggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcaccctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15519 JY8QFUQ01C160X productive (see comment) Homsap IGHV4-61*02 F 947 92.31 204/221 nt 91.86 203/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcGatcgcacgcaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15520 JY8QFUQ01ADNO5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15521 JY8QFUQ01BZ0P1 unknown (see comment) Homsap IGHV3-16*01 ORF 94 53.45 62/116 nt 8 X X 8.X.X [25.5.X.X] null - No rearrangement found cctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15522 JY8QFUQ01BVQT2 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKS*LW#YYFDQW out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggGggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaatcatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 15523 JY8QFUQ01CYPTR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARXNYGDYW# out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaaganataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15524 JY8QFUQ01CDH8H No results 15525 JY8QFUQ01BZPY8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15526 JY8QFUQ01DGWTB productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatnggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactcagg 15527 JY8QFUQ01CH0TM No results 15528 JY8QFUQ01A8ML0 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 7 8 15 7.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) gtctggattcatcttcttgaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15529 JY8QFUQ01B7WRW productive (see comment) Homsap IGHV3-7*01 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 151 76.47 39/51 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.37.11] CGRDERGADLPXDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 191 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaangattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15530 JY8QFUQ01BOXEZ productive (see comment) Homsap IGHV1-3*01 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagCaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15531 JY8QFUQ01A8U3A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtactaacaCcgggggggactaacacagcctacgcgcactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15532 JY8QFUQ01CL9Y8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CAKEGDGSVIPSPVPEWQFDSW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttgacagccatgccatgcactgggtccgtcgggctccagggaaggggctggagtgggtctcggcagttagtggtggtggccattatacatactacgcgcgctccgtgaagggccgatttaccatatccagggacaattcccgaaacatggtgtatttggagatgactggcctgacagccgaggacacggccgtatattattgtgcgaaagagggagacggatcagtgatcccgtctcctgttcctgagtggcaatttgactcctggggccagggaaccctggccacggtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15533 JY8QFUQ01BJ5AZ No results 15534 JY8QFUQ01BF0B7 No results 15535 JY8QFUQ01CJGZM No results 15536 JY8QFUQ01AJ2OA productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15537 JY8QFUQ01AL17I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcagtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtggaactcagg 15538 JY8QFUQ01B9UYL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'T' (1 nucleotides at position 65 to 65 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctTggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15539 JY8QFUQ01AW4CK productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15540 JY8QFUQ01CUROA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 856 88.13 193/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 38 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) aggcctcctggattcaccCTttgggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15541 JY8QFUQ01B69U3 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 872 87.5 196/224 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CTADVPSPLAQNDF# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaagggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctgggccagggaaccctggtcaccgtctcctcagnatccccgaccagccccaaggtcttcccgctgagcctcgaagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 15542 JY8QFUQ01B6YXV productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15543 JY8QFUQ01CTUWH unknown (see comment) Homsap IGHV3-7*03 F (see comment) 733 81.94 177/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggaggggcgtggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15544 JY8QFUQ01AWXID productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 896 89.91 196/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 9 7 12 9.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'GTG' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 3 nucleotides (from position 21 in the user submitted sequence), (do not cause frameshift) tctctggtggctccatcaacaGTGgtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaaccCcgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgcgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15545 JY8QFUQ01CKVV0 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15546 JY8QFUQ01A5FLW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15547 JY8QFUQ01BDK06 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 874 93.03 187/201 nt 92.54 186/201 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-2*01 F 2 10 1 X 10.1.X [1.17.37.11] CARVA*CDLW*SQLLKAL#YSYDMDVW out-of-frame - stop codons in CDR2-IMGT, from codon 57 of V-REGION: 19 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) ctctggtggctccatcaacaatagtacttactactacggctgaatccgccagccccccgggaaggggctggagtggattgggagtctctctacaacccgtccctcatgagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgccgacacggctgtatatcgctgtgcgagagttgcctgatgtgatttgtggtagagccaactgctcaaggccttagtactcctacgatatggacgtctggggccaagggaccacggacgccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15548 JY8QFUQ01BA7JM productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15549 JY8QFUQ01C1TLO No results 15550 JY8QFUQ01CFE76 No results 15551 JY8QFUQ01A857F productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cctctggattcGaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15552 JY8QFUQ01AB599 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 15553 JY8QFUQ01A3YE7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15554 JY8QFUQ01CA8OU productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 777 85.05 182/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 15 8.8.15 [0.17.38.11] CGRGQHIVVVTSKIDLW in-frame + tggatataccttcacctcctactatatctactgggtgcgacaggcccctggacagggactagagtggatgggacaagtcgaccctaatgacgggagaacaaagtacgcacagaagttcgagggccgggccaccgtgaccttcgacaggtccacgagcacagcctacatggagctgagtagcctgagatctgacgacacggccgtgtattattgtggcaggggtcagcacattgtagtggtgactagtaagattgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 15555 JY8QFUQ01C6GOS productive (see comment) Homsap IGHV4-39*03 F 924 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); ctccggtggctccatcaacagtagaaAattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgaccggtgtcgtggaactccag 15556 JY8QFUQ01CTPUF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*08 F (see comment) 755 83.72 180/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVRPSGERFFDFW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctcgctcacgggtttcaagtggggctggatccggcagcccccagggaagggactgcaatggattggacatatctctttcgttggggacaccagttatgacccttccctcagaagtcgagtcgccctttcagtcgacacgtccaagaaccagttctccctgaaactgaactctgtgactcctgcggacacggccgtctattactgtgcgagcgtgcgtccttcgggagaacggttcttcgacttctggggcctgggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15557 JY8QFUQ01DCHH0 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15558 JY8QFUQ01ACLJ7 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15559 JY8QFUQ01BZI5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca 15560 JY8QFUQ01B03TR productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1032 96.82 213/220 nt 96.36 212/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 164 81.63 40/49 nt Homsap IGHD2-21*02 F 3 8 8 7 8.8.7 [2.17.38.11] CARMTDDFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); agtctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagcagtagcaccatCaaaatacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagaatgacagacgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15561 JY8QFUQ01B0V5U No results 15562 JY8QFUQ01DEO1E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15563 JY8QFUQ01CXZ92 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARPGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacctgggcaactcgctcttgactactggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15564 JY8QFUQ01CNPN6 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cctccggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaGggggccggtgtgggtctcacgtattaatgaagacgggCagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15565 JY8QFUQ01BQLNQ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); gttctggaGtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15566 JY8QFUQ01C3D0P unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F or Homsap IGHV3-66*04 F (see comment) 269 72.64 77/106 nt 8 7 X 8.7.X [1.17.1.X] null - No rearrangement found Low V-REGION identity (72,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcaccgtcaataacaactacatgggctgggtccgccaggctccagggaaggggctggagtgggtcatcgcctgcctggtccagggcttcttccccca 15567 JY8QFUQ01DP4QQ No results 15568 JY8QFUQ01B7L34 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctncctggtcaaggactcanttccccgaaccggtgacggtcgtgcgtggaactcag 15569 JY8QFUQ01CX9UQ No results 15570 JY8QFUQ01BY8JZ unproductive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15571 JY8QFUQ01CTEB2 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 94 84.62 22/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found tccgggggacagtgtctctaccaaca 15572 JY8QFUQ01CABSX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15573 JY8QFUQ01BLFO0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 229 73.33 66/90 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 X X 14 X.X.14 [X.X.30.11] CAKEEGATGVYYVDHW in-frame - Low V-REGION identity (73,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttaccacctccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15574 JY8QFUQ01DGVTM No results 15575 JY8QFUQ01AZMOO unproductive Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F 1011 97.2 208/214 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CARGVRTVVTALSYGMDV## out-of-frame + tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtggtaacacaggctatgcacagaagttccagggcagagtcatcatgaccaggaacacctccataagcacagcctacatggagctgagcagcctgagttctgaggacagggccgtgtattactgtgcgagaggtgtccgaacggtggtgactgctctttcctacggtatggacgtctggggcccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15576 JY8QFUQ01CYSU0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRWKMDRSGVSAAATDVFGMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctcgggattcaccttcagtggctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatggtaagaataaatacatctactatgcagactcactgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaccaacctgagagccgaggacacggctctatattactgtgtgagatggaagatggataggagtggtgtaagtgcagcggcaacagacgttttcggtatggacgtctggggccaagggaccacagtcaccgtctcctcagcctccaccaagggctcatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 15577 JY8QFUQ01C825R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcttggaactca 15578 JY8QFUQ01ALAFA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 418 96.63 86/89 nt 8 3 X 8.3.X [1.17.X.X] null + No rearrangement found ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagta 15579 JY8QFUQ01DO5NY productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1005 95.45 210/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15580 JY8QFUQ01CTEIK No results 15581 JY8QFUQ01AO14S productive Homsap IGHV3-7*01 F 1011 97.2 208/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15582 JY8QFUQ01C9HGQ unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 138 52.69 98/186 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccggagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15583 JY8QFUQ01AMXZ6 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 867 89.72 192/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + tcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15584 JY8QFUQ01CSU1I productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 666 78.34 170/217 nt 77.42 168/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcgccacttatcattggtggAacttgggtccgccagaccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15585 JY8QFUQ01C7775 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 389 75.54 105/139 nt 8 8 X 8.8.X [1.17.11.X] null - No rearrangement found Low V-REGION identity (75,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15586 JY8QFUQ01BBQPA productive (see comment) Homsap IGHV1-2*02 F (see comment) 750 83.18 178/214 nt 82.71 177/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGLSYDSSPYWGYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'GA' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift); tggatacatcttcaatgacttctacatatattgggtgcgacaggcccctggGAcaaggggcttgagtggatgggatggttcaaccctaatagtcgtgtcacagactatgcagagaaatttcagggcagggtcaccatgaccggggacccgtcccgcagcacagtccacctgaaactgacccgcctgaagtcggacgacacggccgtctattactgcgcgagaggtctctcctatgacagtagtccttattggggctactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15587 JY8QFUQ01CXGJG productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15588 JY8QFUQ01DAR6E No results 15589 JY8QFUQ01C3CCF productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 924 91.36 201/220 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + ctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccc 15590 JY8QFUQ01BO1TD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15591 JY8QFUQ01BEZH7 unproductive Homsap IGHV3-7*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag 15592 JY8QFUQ01CQJD2 productive (see comment) Homsap IGHV3-48*01 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15593 JY8QFUQ01AZO8K No results 15594 JY8QFUQ01BSAMC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15595 JY8QFUQ01C8X0V productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaagccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 15596 JY8QFUQ01BQPM7 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CARLGARFGD#DYW out-of-frame - stop codons in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15597 JY8QFUQ01AST77 No results 15598 JY8QFUQ01BZ99I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15599 JY8QFUQ01AP9Y7 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CATDRCTGGTCCPHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacactttcaccagttattatatacactgggtgcgacaggCcccctggacaggggcttgagtggatgggagttgtcaaccctggtgctgaatacacactctacgcacagaagttccagggcagactcaccttgaccagggacacgtccacgagcacagtctacatggagttgagtagcctgagatctgaggacacggccctgtattactgtgcgacagataggtgtactggtggtacctgctgtccacattactggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15600 JY8QFUQ01C5U4M productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 972 94.47 205/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-26*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARVGELQYWHFDLW in-frame + gtctggattcacctttggtgattatggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggattggcagtggtacaggttatgcagattctgtgaggggccgattcaccatctccagagacaacgccaagaactccctgtatctacaaatgagcagtctgagagccgaggacacggccttgtatcagtgtgcgagagttggggagctacaatactggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15601 JY8QFUQ01ABSM6 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 15602 JY8QFUQ01C79YW unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 651 78.04 167/214 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt 8 8 X 8.8.X [0.17.38.6] RTGD (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION identity (78,04% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15603 JY8QFUQ01CCGPP productive (see comment) Homsap IGHV3-33*03 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) gcgtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15604 JY8QFUQ01B84I1 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15605 JY8QFUQ01A2YKB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 951 92.73 204/220 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gccgtctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg 15606 JY8QFUQ01CWQ1B productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15607 JY8QFUQ01B7MKI productive Homsap IGHV4-61*08 F (see comment) 827 87.44 188/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01B7MKI ; 10 AA in Homsap_IGHV4-61*08) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccctcgggggtttcgcctggagttggatccggcagcgcccgggaaagggactggaatggattggacatatctctcacatcgggagctccaactatgagccctccctcacgagtcgactcaccatgtcagtagacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15608 JY8QFUQ01CD9VK productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ6*02 F 121 66.13 41/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcCccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggccaagggactacttccccgaaccggtgacggtgtcgtggaactcag 15609 JY8QFUQ01CYAT8 productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 743 82.49 179/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 3 10 6 15 10.6.15 [1.17.37.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) ctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtggggcacctattacaacccgtctctcaagagtcgacttgccctgtcattagacgcgtctaataatgtttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15610 JY8QFUQ01CGGQ6 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggGggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15611 JY8QFUQ01CEC9H No results 15612 JY8QFUQ01AMKH6 unproductive Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGPVSGWYTDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggcccagggaaccctggtcaacgtctcatcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacacgcacccccaaggcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15613 JY8QFUQ01B9U1R No results 15614 JY8QFUQ01BUYQ1 productive (see comment) Homsap IGHV3-7*01 F 1030 97.69 211/216 nt 97.22 210/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.16.38.11] CVSSPYFYDSNGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15615 JY8QFUQ01CFP87 productive Homsap IGHV1-2*02 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 1 8 8 12 8.8.12 [0.17.38.11] CATDVPAGQLWGYW in-frame - tggatacacattcaccgacaactatatgcactgggtgcggcaggcccctggacaggggcttgagtggatgggatggatcgaacctaacagtggagacacaaactatgcacaaaagtttcagggcagggtcaccatgacgagggacacgtccatcgccacagcctacatggagttgagcaggctgagagctgacgacacggccgtgtactactgtgcgaccgacgtccccgcagggcaactctggggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15616 JY8QFUQ01AKND1 No results 15617 JY8QFUQ01DREWH No results 15618 JY8QFUQ01CV650 unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [0.17.38.11] CAMGGALCGGDR*#FDYW out-of-frame - stop codons in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggatacagttttaccacctactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtgggtgggaattatatctcctggtgactctgaaatccgatacagcccgtccttcgaaggccaggtcaccatctcagccgacaagtccaccagcaccgcctacctgcagtggaacaccctgaaggcctcggacactgccatgtattattgtgcgatggggggggcactttgtggtggtgacaggtagatttgactattggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15619 JY8QFUQ01DGD7Q productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 15620 JY8QFUQ01DCK52 unproductive Homsap IGHV3-7*01 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.37.11] CGRDERGADLPNDS## out-of-frame + in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggccctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15621 JY8QFUQ01AYJ9K productive Homsap IGHV1-3*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15622 JY8QFUQ01B4FSE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.16.38.11] CAKRLQAVADDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) gcctctggattcatctttagtagctatgccatgggctgggtccgccagGgctccagggaaggggctgagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15623 JY8QFUQ01AQ3NT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15624 JY8QFUQ01BA3GM unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CTRVGTFNWF#PW out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggattcaactttgcagattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatTgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 15625 JY8QFUQ01AN075 No results 15626 JY8QFUQ01BLVIV productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15627 JY8QFUQ01DNJ91 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15628 JY8QFUQ01AMSZ1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcaggc 15629 JY8QFUQ01BX0V1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRYPRSTAITAPDY## out-of-frame + cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15630 JY8QFUQ01AXQWW unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGIVMK#DYW out-of-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15631 JY8QFUQ01DNXAW productive (see comment) Homsap IGHV3-7*01 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD3-3*01 F 1 8 8 11 8.8.11 [2.17.38.11] CVRPPRPCFRYLG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); gccaatggattcacctttagtgactattggatgagttggttccgccaggccccagggaaggggccggagtgggtggccaacataaacgaagatggatctgggcaacagtatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgCtttttagaaatgaacagcctgagaatcgacgacacggctgtgtattactgtgtgagaccccccagaccgtgctttagatatctgggggccaggggggcagtggtcaccgtctcttcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctgggtccaggggcttctttccccc 15632 JY8QFUQ01CLFQD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15633 JY8QFUQ01B8BYY unproductive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 X 10.7.X [1.17.38.11] CARDPQGYL*WW*LPLFC#MDVW out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15634 JY8QFUQ01AW5SW unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15635 JY8QFUQ01CXFOY unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15636 JY8QFUQ01BDDL7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); gggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgagacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15637 JY8QFUQ01A71MM No results 15638 JY8QFUQ01CLEH3 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgggtccgacaggcccctgGgacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15639 JY8QFUQ01A9G63 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtcatcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 15640 JY8QFUQ01BX7EL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 111 53.19 75/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found cctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcacggcggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15641 JY8QFUQ01CQF8T No results 15642 JY8QFUQ01C277Q productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15643 JY8QFUQ01A2UOO unproductive (see comment) Homsap IGHV1-69*05 F (see comment) 235 73.12 68/93 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 1 X X 14 X.X.14 [X.X.31.11] CATSFGKISTPYFEHW in-frame - stop codons Low V-REGION identity (73,12% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cggacacaccctcattgaattgtccatgcactggacacagcctacatggagctgagcagcctgacatctgacgacacggccgtgtattactgtgcaacatcattcgggaagatttcaactccctactttgaacactggggccagggaaccctggtcagcgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15644 JY8QFUQ01B6FD5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15645 JY8QFUQ01DNN2A unproductive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVRG*RWCQFWRN#DYW out-of-frame - stop codons tctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgagggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15646 JY8QFUQ01B5FEA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15647 JY8QFUQ01BQBSK unproductive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFEY## out-of-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccaggggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 15648 JY8QFUQ01AW0RY unproductive (see comment) Homsap IGHV1-18*01 F 983 95.77 204/213 nt 94.84 202/213 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [X.17.38.11] CARGL*G#YSYGMDVW out-of-frame - stop codons in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); aggtacacctttaccagctatggtattagctgggtgcgacaGggcccctggacCaagggcttgantggatgggatggatcagcgtttacaatggtaacacaaactatgcagagaagctccagggcagagtcaccatgaccacagacagatccacgagaacagcctacatggagttgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagggctctagggggctactcctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15649 JY8QFUQ01AK4AI productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 930 91.03 203/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTRPRGWEPLGLDYW in-frame + ctctggattcactttcagtgacgcctggatggtctgggtccgccaggctccagggaaggggctggagtgggttggccttattaagaccaaacctgatggttggacaacaatctactctgcacccgtgaaaggcagattcatcatttcaagagatgattcaaaaaacatggtgtttctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtaccacacggccccgggggtgggaaccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15650 JY8QFUQ01BGKIP productive Homsap IGHV3-30*01 F 942 92.27 203/220 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [2.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - agcctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15651 JY8QFUQ01AVFZ6 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15652 JY8QFUQ01CA8KR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 726 81.36 179/220 nt 80.91 178/220 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [2.17.38.11] CAKVKGYGGNWFQPHFDRW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); agtctctggattcTgccttcgaggggtctgtcgtgacctgggtccgacaggctccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaattccaaggacacggtctatctgcagatgaacggcctgagagtcgaagactcggcccgttattattgtgcgaaagtgaagggctacggcggcaattggttccagcctcactttgaccgctggggccagggcaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15653 JY8QFUQ01DVIY1 No results 15654 JY8QFUQ01APJF5 unproductive Homsap IGHV3-48*02 F 483 86.15 112/130 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD1-1*01 F 3 X 5 X X.5.X [X.X.38.11] CASGGKERLRSTTGLLSRHGRL# out-of-frame - ctctggactcaccttcagcagctataactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtgggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15655 JY8QFUQ01A8Y8J productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD2-8*02 F 2 8 8 24 8.8.24 [1.17.38.11] CVRAAGYCPGGDDCYKIGTHDSLDIW in-frame - gtctggattcaccttcagtacctatggcacacattgggtccgccaggctccaggcaaggggctggactgggtggcagttagttggcatgatggaagtcaggaatattatgcagactccgtgaggggccgattcactgtctccagagacaattccaagaacacggcatatctgcatatgaatgtcctgagaggcgaagacacggctgtctactactgtgtgagagcggcggggtactgtcctggtggtgatgactgctacaagatcggaactcatgactcccttgatatctggggccgaggggcagttgtctccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15656 JY8QFUQ01DM0RC unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDSDSSGYARYDSMDV## out-of-frame - Other possibilities: Homsap_IGHJ2*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctgggggccaagggaccgcggtcaccgtctcatcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15657 JY8QFUQ01B2F7W No results 15658 JY8QFUQ01AQED1 productive Homsap IGHV1-3*01 F 948 93.93 201/214 nt Homsap IGHJ1*01 F 206 88.46 46/52 nt Homsap IGHD5-12*01 F 3 8 8 12 8.8.12 [0.17.38.11] CARPGYGDNYFHHW in-frame - tggattcaccttcactgactatgctatgcattgggtgcgccaggcccccggacaagggcttgagtggatgggatggatcaacgctggcaatggaaacacaaaatattcactgaagttccagggcagagtcaccattaccagggacacatccgcgagcacagcctatctggagttgactagcctgagatctgaggacacggctgtatattactgtgcgcgccctgggtacggtgacaattatttccaccactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15659 JY8QFUQ01AQSR8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-8*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGQRYCSNGVCSSF#YSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctggattcacctacagcagcGtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcgcagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15660 JY8QFUQ01B0V4X productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagagcccatcggtcttccccctggcaccctcctccaaagagcacctctggggggcacagccggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 15661 JY8QFUQ01BSGWN productive Homsap IGHV3-48*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDMIIFGGALDNW in-frame - tggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15662 JY8QFUQ01BY4MW productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15663 JY8QFUQ01AFJGI unproductive (see comment) Homsap IGHV4-55*03 P, or Homsap IGHV4-55*09 P (see comment) 376 63.35 140/221 nt 62.44 138/221 nt Homsap IGHJ4*02 F 91 64.58 31/48 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [4.17.38.11] CTRGSLTGTYPSDPX# out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01AFJGI ; 9 AA in Homsap_IGHV4-55*03), and low V-REGION identity (63,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'GG' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'TCTGAG' (6 nucleotides at position 102 to 107 in the user submitted sequence), (do not cause frameshift); ttcggagacgatatatctggagacagtgttacttgggaactggatcagggcagtcccccaggggaGGggggcttgagtggctcgggcgtatctttcacaggTCTGAGtggcataccgactacttggcgtctgttagaggccgaatctccatggatgtcgacacgtccaagaaccacttcaccctgcagctccgctctctgactcccgacgacacggctacatatttctgtacaagaggctctctaactgggacatatccttctgacccantggggtctggggcaccccagtgaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccc 15664 JY8QFUQ01ARRMJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15665 JY8QFUQ01COA9P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.37.11] CVKGWNYHSATFGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 78 of V-REGION: 1 nucleotides (from position 141 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccatttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15666 JY8QFUQ01CLNQ1 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15667 JY8QFUQ01BJ0OV productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tctggattcaccttcagGtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15668 JY8QFUQ01B2RVH No results 15669 JY8QFUQ01B0CZW unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15670 JY8QFUQ01B8F4K unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 15671 JY8QFUQ01ATVSF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 106 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15672 JY8QFUQ01CEJWZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15673 JY8QFUQ01AKFJR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); cctctggattGcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 15674 JY8QFUQ01CFP7H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15675 JY8QFUQ01DTDBD productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-11*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CARDRESTVTTRLDSDHW in-frame + ctctggattcaccttcgacagttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccatcagtagaagtagtagttacatatattacgcagactcagtgaagggccggttcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagacccggggacacggctatatattactgtgcgagagaccgggagtctacagtgactacgcgtctggactccgatcactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15676 JY8QFUQ01DMIUH productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 7 8 20 7.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) tttctggatacagtttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15677 JY8QFUQ01B95ZV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame - ctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15678 JY8QFUQ01AT6GX productive Homsap IGHV3-9*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccccaa 15679 JY8QFUQ01AD8Y1 productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDEIPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcactacatattccatgcactgggtccgccaggctccaggcaaggGggctagaatgggtggcagttatatcatatgatggaaaaaaaaagtcttatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtgtattactgtgccagagatgagatcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15680 JY8QFUQ01AVP9X unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctgggggccagggaacccgaggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15681 JY8QFUQ01B34Y6 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 83.71 185/221 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-3*01 F 1 10 7 X 10.7.X [1.17.38.11] CARHRSFGVIIVNYFES## out-of-frame + Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactgGgggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctgggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 15682 JY8QFUQ01DN8AR productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.37.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) tggagtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgGgggatcatctatcctggtacctctgagaccagatacagcccgtccttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15683 JY8QFUQ01BC8E3 productive (see comment) Homsap IGHV3-48*03 F 859 88.89 192/216 nt 87.96 190/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgcatgaactgggtccgcctggttcaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15684 JY8QFUQ01ARJL7 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 10 7 X 10.7.X [1.17.38.X] null - No rearrangement found ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcgggccaactactgggggcccaggggaaccctgggtcaccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15685 JY8QFUQ01CKEJT No results 15686 JY8QFUQ01C45M6 productive Homsap IGHV4-61*02 F 867 87.89 196/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [2.17.38.11] CARSGWDNQFDFW in-frame - tgtctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcccggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15687 JY8QFUQ01AYGE6 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) gcctcctggattcacCctttggttattatggcatggactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15688 JY8QFUQ01DH1ZV No results 15689 JY8QFUQ01CR20C No results 15690 JY8QFUQ01BFS9F productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctcggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 15691 JY8QFUQ01B1466 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 710 91.12 154/169 nt 8 7 X 8.7.X [1.17.22.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B1466 ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatct 15692 JY8QFUQ01B1INU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15693 JY8QFUQ01CGPC7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 15694 JY8QFUQ01A1ALH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15695 JY8QFUQ01AUD41 productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15696 JY8QFUQ01BO1BF productive Homsap IGHV4-59*02 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARHSMGVTIVRGHWFDPW in-frame + tctctggtggctccgtcagcagttattactggagctggatccgacagcccccagggaagggactggagtggattggctatatccatgacagtgggagcagcaactacaacccctccctcaagagtcgagtcaccatatctgtggacacgtccaagaaccagttctccctgaagctgacttctgtgaccgctgcggacacggccgtatattactgtgcgagacattctatgggtgttactatagttcggggacactggttcgacccctggggccagggaaccctggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15697 JY8QFUQ01DBZUC productive (see comment) Homsap IGHV3-7*01 F 937 94.29 198/210 nt 93.33 196/210 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 7 8 14 7.8.14 [X.16.38.11] CARGSYYYYDTNGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift) atttacctttacaaattattggagagctgggtccgccaggctccagggaTgggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15698 JY8QFUQ01AX3MM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 7 8 18 7.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 23 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaacacagaatgaattgggtccgtcaggctccagggaaggggctcgaatgggtctcgtccattaccagttccagtagttacatatactacgcagactcggtgacgggccgattcaccatctccagagacaacgccaaggggtcactctatctgcacatgagctaccttagagccgaggacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgaaaggtctgcttttgatatctggggccaagggacaatggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15699 JY8QFUQ01AGPYP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [1.17.37.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) ctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcatgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15700 JY8QFUQ01AXHTR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcatcttcagtagctactggatgcactggg 15701 JY8QFUQ01B82D6 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15702 JY8QFUQ01AP05X productive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cgtctggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15703 JY8QFUQ01C4O02 unproductive Homsap IGHV3-48*02 F 991 94.98 208/219 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [2.17.38.11] CARPAGEGDPFL##YYSGLDVW out-of-frame + gcctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15704 JY8QFUQ01CPEK6 No results 15705 JY8QFUQ01A3BPF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcacctttaccaactatggcatgagctgg 15706 JY8QFUQ01BW2GU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 82.19 180/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15707 JY8QFUQ01AY8NK productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15708 JY8QFUQ01C2A3X productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15709 JY8QFUQ01B1DWD unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARKGPQKRWLPTAM#DMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggcccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15710 JY8QFUQ01ANKGS No results 15711 JY8QFUQ01ALIBX No results 15712 JY8QFUQ01CVNSL productive Homsap IGHV4-61*02 F 817 85.59 190/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [2.17.38.11] CARCPNYNIGTRGFDYW in-frame - gtttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15713 JY8QFUQ01DETD7 unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 92.59 200/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggaacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15714 JY8QFUQ01CPGZT productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15715 JY8QFUQ01CZKYX productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15716 JY8QFUQ01DSZOW No results 15717 JY8QFUQ01CHR4R unknown (see comment) Homsap IGHV1-8*01 F 200 55.45 112/202 nt 8 8 X 8.8.X [0.17.34.X] null - No rearrangement found tggagacaccttcaccagttatgatatccactgggtgcgacaggcctctggacaagggcttgagtggatgggatggatgaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15718 JY8QFUQ01A3AS4 No results 15719 JY8QFUQ01AXYES productive Homsap IGHV3-48*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVPGPNDNYFDYW in-frame + cctctggattcagcttcagagactatggcatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatacattggtaggattattagtgacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagggacgacgacacggctgtctatttctgtgcgagagatgtcccgggccccaatgacaactactttgactactggggccagggaaccctgcttaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccca 15720 JY8QFUQ01BL2JT No results 15721 JY8QFUQ01AVU4K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 15722 JY8QFUQ01BB01O productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15723 JY8QFUQ01CJBN2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVMREHYYGAGNYPWGGMEVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggGactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15724 JY8QFUQ01DED91 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccAaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15725 JY8QFUQ01B5PQ5 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.37.11] CANASPV*LE#YFYYYGMDVW out-of-frame + stop codons in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 199 in the user submitted sequence), (cause frameshift) tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacggccgtatattactgtgcgaatgcctcccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 15726 JY8QFUQ01DBC1W productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaAaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15727 JY8QFUQ01A2LE9 unproductive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKARIYFYGSGVIP#FDYW out-of-frame + cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcgggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15728 JY8QFUQ01BJOG2 No results 15729 JY8QFUQ01BSYZW productive (see comment) Homsap IGHV4-4*07 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaaTcccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15730 JY8QFUQ01AWCOE productive (see comment) Homsap IGHV4-59*03 F (see comment) 764 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARGDDSTGYGEYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaatggatactactgcagctggttccggcaggccccaggaaagggactggagtgggtcgggttTtatacattggagtgGggaaaaccgattacaatcctgccctcgagagtcgagtcagtctatccatggacacgtccaagagtcaagtctccctgaaggtgacctctgtgaccgctgcggacacggccgtctattactgcgcgagaggcgacgacagtactggttacggggaatattggggccagggaaggctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15731 JY8QFUQ01BTOR9 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*07 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [X.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 190 to 190 in the user submitted sequence), (cause frameshift); tggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaAaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15732 JY8QFUQ01BPIPL No results 15733 JY8QFUQ01DUWI8 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15734 JY8QFUQ01BW51W unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 95.19 198/208 nt 94.71 197/208 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD2-21*02 F 1 6 8 X 6.8.X [X.17.38.11] CARLCGNDCRNDDF*YL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); caccttcagtacctactggatgcactgggtccgccaagttccagggaAaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgatttttgatatctgggggccaagggacattggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15735 JY8QFUQ01A312M productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15736 JY8QFUQ01AVHAL No results 15737 JY8QFUQ01CQQ2D productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15738 JY8QFUQ01CBL5V No results 15739 JY8QFUQ01CF885 productive (see comment) Homsap IGHV3-30*10 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 1 8 8 16 8.8.16 [1.17.37.11] CSRGTTGTTDDSRLFQHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) ctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttc 15740 JY8QFUQ01A17D9 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 912 92.06 197/214 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARHNYGNEKYIMDVW in-frame - tggatacaactttgccacctattggatcggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatggtctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15741 JY8QFUQ01A2MSQ productive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'GT' (2 nucleotides at position 13 to 14 in the user submitted sequence), (cause frameshift); tctggattcaccGTtttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15742 JY8QFUQ01BXH98 productive (see comment) Homsap IGHV3-9*01 F (see comment) 786 83.86 187/223 nt 83.41 186/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [3.17.38.11] CGRIAKPGLGALDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); aggggcgttgggattcacAttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15743 JY8QFUQ01BQ2GI productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctgtggactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15744 JY8QFUQ01BTX5G productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 735 81.74 179/219 nt 81.28 178/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 6 15 10.6.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) tctcgggtgcttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15745 JY8QFUQ01CDCBG productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15746 JY8QFUQ01BUYZM unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAGSGRDPYGINVW# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctgggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15747 JY8QFUQ01C2JMT productive Homsap IGHV3-43*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - cgtcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15748 JY8QFUQ01AF4LW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggGggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccccag 15749 JY8QFUQ01BM12K productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*04 F 990 89.75 219/244 nt 89.34 218/244 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD2-2*01 F 2 10 7 13 10.7.13 [9.17.38.11] CARKYGSSTNGFDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcacgttctctggattctcactcaacacAcaggggaatgggcgtggactggatccgtcagcccccaggaaaggccctagagtggctaggcctcatttactgggatgatgatacgcgctacagcccatctctgaggaacaggctcagcatcaccaaggacacttccaaaaaccaggtggtcctgacactgaccaacgtggacgctatggacacaggcacatattattgtgcgcgcaaatatggcagcagtacgaacggattcgacccctggggccagggactcctggtcaccgtctctcagcatccccgaccagccccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15750 JY8QFUQ01ANBAE productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 15751 JY8QFUQ01BGCXQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 766 82.02 187/228 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [5.17.38.11] CARDDGGHMTLDVW in-frame - Low V-REGION identity (82,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtggccaatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15752 JY8QFUQ01CUHEG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15753 JY8QFUQ01CG6E8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15754 JY8QFUQ01AFT0Y No results 15755 JY8QFUQ01CQS1T productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15756 JY8QFUQ01B2OMV unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F (see comment) 328 64.8 116/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (64,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcactagaagtcccatgaattgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15757 JY8QFUQ01ADA8M No results 15758 JY8QFUQ01DJ645 unproductive (see comment) Homsap IGHV3-9*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'GT' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); ctctggattcacctttcatgattaGTagccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15759 JY8QFUQ01B7SJP No results 15760 JY8QFUQ01B5OYN unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 1 8 8 18 8.8.18 [1.17.38.11] CARGEFLL*N*WSKGFLDYW in-frame + stop codons cctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaatttttactatgaaactagtggtcgaaggggtttttggactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15761 JY8QFUQ01CZT8X unknown (see comment) Homsap IGHV4-4*07 F 809 86.51 186/215 nt 86.05 185/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttgattccggcagcccgccgagaaggGgactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccgaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 15762 JY8QFUQ01DNEFC unproductive Homsap IGHV3-33*03 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDWGSSGWFGRC#DVW out-of-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagattgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15763 JY8QFUQ01B7XS9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtagtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15764 JY8QFUQ01BW0AQ productive (see comment) Homsap IGHV3-48*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [2.17.38.11] CARGQKWLQVLRWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgacagatacagtatgaactAgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15765 JY8QFUQ01AJ58T unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaagtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15766 JY8QFUQ01CHQBV productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 820 86.3 189/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKVGNLYFFEYW in-frame - gcctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15767 JY8QFUQ01CELW1 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 709 81.69 174/213 nt 81.22 173/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.37.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 76 of V-REGION: 1 nucleotides (from position 130 in the user submitted sequence), (cause frameshift) ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 15768 JY8QFUQ01DSB95 No results 15769 JY8QFUQ01BWZ3O unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDLYGADDL## out-of-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggtccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15770 JY8QFUQ01CIYFN No results 15771 JY8QFUQ01B08HB No results 15772 JY8QFUQ01BYREX No results 15773 JY8QFUQ01C2ROO productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctcgacacgcaccccccaagatgggaacgtggtcgtcgcagtgcctggtccccagggctcttcccccagga 15774 JY8QFUQ01BEX6B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [0.17.38.11] CAKVVWSLWYFDLW in-frame - ctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctagtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15775 JY8QFUQ01AJ8J4 No results 15776 JY8QFUQ01B6WCT productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 87.78 194/221 nt Homsap IGHJ4*01 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 3 10 7 11 10.7.11 [1.17.38.11] CARAREFLTFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaacaatgatActtttctactggaactggatccggcaggccgccgggaagggactgcagtggattgggcgtatgtatgccagtgggaccactaactacaaccCcctccctcaagagtcgagtcaccatgtcagtagtcacgtcaaagaatcaattttccctgaagttgagttctgtgaccgccgcagacacggccatttactactgtgcgagggcccgagagtttctcacctttgactcctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15777 JY8QFUQ01AHQEV unproductive Homsap IGHV3-48*03 F 923 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDCDSGECNFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15778 JY8QFUQ01AG53L productive (see comment) Homsap IGHV4-61*02 F 834 86.82 191/220 nt 85.91 189/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.37.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 217 in the user submitted sequence), (cause frameshift) tctctggtgcctccataaataggggtaattattactGggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttattttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15779 JY8QFUQ01AMHRT unknown (see comment) Homsap IGHV2-5*03 F 177 54.69 105/192 nt 10 7 X 10.7.X [9.17.25.X] null + No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 15780 JY8QFUQ01AFICH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1005 95.45 210/220 nt 94.55 208/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ggcctctggattcagcttGcaatagttactggatgcactgggtccgccaagctccagGggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15781 JY8QFUQ01ALMSJ productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 7 7 8 7.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcctctgcagcctctggattcattgtcaatagcactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15782 JY8QFUQ01CEN0W unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15783 JY8QFUQ01CG8U2 productive (see comment) Homsap IGHV3-66*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVGATVAFQYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataGggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtgggagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttcccccaa 15784 JY8QFUQ01BI18V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtccgtgggaactcag 15785 JY8QFUQ01CHGC7 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 912 89.69 200/223 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD2-2*01 F 2 8 8 18 8.8.18 [3.17.38.11] CARYCSSDSCQGYHDAFDVW in-frame - taaggcttctggatacatcttcacgaaccactggatcggctgggtgcgccagatgccgggtagaggcctggagtggatggggatcatctatcctggtgactccgattccagatacggcccgtccgcccaaggccaggtcaccttctcagtcgacaagtccatcgccaccgcctaccttcagtggagtagcctgaaggcctcggacaccgccacgtactactgcgcgagatattgtagtagtgacagctgccaagggtaccatgatgcttttgatgtctggggccaagggacaatggtctccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15786 JY8QFUQ01DMFVC unknown (see comment) Homsap IGHV4-4*07 F 890 90.7 195/215 nt 89.3 192/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'TGATTC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagTGATTCtcactactggagttggatccggcagcccgccggGgaagggactggagtggattgggcgtgtctacgccagtgGggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtgctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagaacacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 15787 JY8QFUQ01DPWGM productive (see comment) Homsap IGHV3-72*01 F 953 91.96 206/224 nt 91.07 204/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'AG' (2 nucleotides at position 54 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'T' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccaAGggaagggggctggagtTgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctgcgctctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15788 JY8QFUQ01BAFLC productive Homsap IGHV3-7*01 F 887 89.45 195/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15789 JY8QFUQ01DHSUC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame - ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt 15790 JY8QFUQ01C6XVX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15791 JY8QFUQ01B5NWN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15792 JY8QFUQ01AGEU2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVRGDYGGAPRTLLRP#YGLDVW out-of-frame + cctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagtcgaggacacggctatgtattattgtgtgagaggggactacggtggcgccccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15793 JY8QFUQ01CMN9M unproductive Homsap IGHV3-9*01 F 963 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDAMGGAGDWAAFG#LG out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggcccagggggacaatggtcactgtctcttcaggcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15794 JY8QFUQ01CNCFI unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15795 JY8QFUQ01C95SC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15796 JY8QFUQ01C65EF No results 15797 JY8QFUQ01BCK6X productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 942 94.31 199/211 nt 92.89 196/211 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [0.16.37.11] CARDGGHSYGPSFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) tggatacaccttcaccaggtacattatgcactgggtgcgacaggccctggacaaggcttgagtggatgggaataatcaaccctagaggtgttagcagaagctacgcacagaagttccaggcagagtcaccatgaccaccgacacgtccacgagcacagtctatatggagctaaacagcctgagatctgaggacacggccgtttattactgtgcgagagatggagggcacagctatggaccctcctttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15798 JY8QFUQ01CHME0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15799 JY8QFUQ01AXA7J productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 15800 JY8QFUQ01CERKI unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARPGGDCLL*WW*LLR#PG out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); cctctggattcagcttcaatagttGactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccagggggggattgcctattgtagtggtggtagctgctacgacccctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15801 JY8QFUQ01CHW93 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15802 JY8QFUQ01ABNQY unproductive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15803 JY8QFUQ01BTJ3Q unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGDMMRTTMS#DFW out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg 15804 JY8QFUQ01A9XZY productive (see comment) Homsap IGHV3-7*01 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARTSSREITDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'AC' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); gcctctggaGttcacctttagtggctattggatgagttgggtccgccaggctACccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15805 JY8QFUQ01CLGDD productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARDPSGSGWAFESW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gcgtctggatTtccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15806 JY8QFUQ01BWJEK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt 90.78 197/217 nt 8 8 X 8.8.X [2.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctctagggaagggctggagtggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagaggatcggtgacttgggcgggctggttcgaccccctgggggccaggggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15807 JY8QFUQ01BHQ6M productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame + ctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtgcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 15808 JY8QFUQ01B02FB productive Homsap IGHV3-48*01 F 865 88.58 194/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + gtctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15809 JY8QFUQ01DB3OE productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15810 JY8QFUQ01A24GB unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctgaaatcaccttcagcgaccactacatgagctggatccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15811 JY8QFUQ01BQMY8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1031 97.25 212/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15812 JY8QFUQ01AWSL1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame - ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15813 JY8QFUQ01DG1D0 productive Homsap IGHV4-61*02 F 852 87.73 193/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame + ctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15814 JY8QFUQ01AA37K productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15815 JY8QFUQ01CSDHI productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15816 JY8QFUQ01DXGBB unproductive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1025 95.54 214/224 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD4-11*01 ORF 2 8 10 X 8.10.X [1.17.38.11] CARHEGTPVSDVGGYGMDVW# out-of-frame + cctctggattcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggaatgggttggccgtattagaagcagagcttacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctgggggccaaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 15817 JY8QFUQ01BAWV8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15818 JY8QFUQ01APXX1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt 98.62 215/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'CA' (2 nucleotides at position 83 to 84 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaagGgggctggagtgggtctcatccCAattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15819 JY8QFUQ01AN89A unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaagccttggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcg 15820 JY8QFUQ01C6WFJ No results 15821 JY8QFUQ01BOLEF productive (see comment) Homsap IGHV3-48*01 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15822 JY8QFUQ01BR20I unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD4-11*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CVRDSGPVRLR*VRV#MDVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggcgtggaaGgtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaGggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggccccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15823 JY8QFUQ01CQO4K No results 15824 JY8QFUQ01AVD8T unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame - cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggcagcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15825 JY8QFUQ01AHVR6 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 267 62.42 103/165 nt 8 10 X 8.10.X [1.17.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01AHVR6 ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15826 JY8QFUQ01CCJDP productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15827 JY8QFUQ01BSK8W productive (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 90.13 201/223 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggtttccCccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtttggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15828 JY8QFUQ01BU2CX unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRNNYYSDY## out-of-frame + gtctggattcaacttcggaagttatggcatgcgctgggcccgccaggctccaggcaaggggctggagtgggtggcatttatttggtatgacggaagaaataaatattatgcagactccgttaagggccgattcaccatctccagagacaattccgagagcacactggatctgcaaatgaatagcctgagagccgaagacacggctgtctattactgtgcgagggataggaataattactactccgactactggggccaggggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15829 JY8QFUQ01A5V7V productive Homsap IGHV4-61*02 F 916 92.49 197/213 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD6-13*01 F 2 9 7 19 9.7.19 [X.17.38.11] CAREAPKAAANSYNSYVMDVW in-frame + ggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggcctggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctccctgaagctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaagcgcccaaggcagcagctaattcctacaactcttacgttatggacgtctggggccaagggaccacggtcaccgtcttctcagcatccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15830 JY8QFUQ01DH57H productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15831 JY8QFUQ01CH326 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1056 99.53 213/214 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [0.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame + tggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgattccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15832 JY8QFUQ01CKANK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15833 JY8QFUQ01DE136 No results 15834 JY8QFUQ01BI5WK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 912 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) ctctgggattcacctttagcagccntcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15835 JY8QFUQ01CW2RH No results 15836 JY8QFUQ01DG254 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtGacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15837 JY8QFUQ01AFE6Z unproductive (see comment) Homsap IGHV3-38*01 ORF, or Homsap IGHV3-66*02 F (see comment) 732 82.71 177/214 nt 81.31 174/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 6 11 8.6.11 [2.17.38.11] CARHLMVYALDVW in-frame - stop codons Low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'TCT' (3 nucleotides at position 82 to 84 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'G' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaGggggctggagtgggtctcagTCTtatttagtactggcactgcatactacgcagactccGtgaaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15838 JY8QFUQ01ADT3T No results 15839 JY8QFUQ01AJIO8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - gcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15840 JY8QFUQ01BBX5W No results 15841 JY8QFUQ01BRYZ3 productive (see comment) Homsap IGHV3-48*02 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARDMIIFGGALDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcgccttcagtagttccagcatgaactggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15842 JY8QFUQ01AP3M5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15843 JY8QFUQ01B71ED productive Homsap IGHV3-9*01 F 802 85.39 187/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKDLSGRPKDMHGMDVW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gcctctgggttcagttttagcaattatgccatgcactgggtccgtcaagctccagggaagggcctgcaatgggtctcacgtattaattggaacagtggaaacatagcctatgcggcctctgtgaggggccgattcaccgtctccagagacgacgccgagcactccctgtatttacaaatgaatggtctgacaactgaagacacggccttatactattgtgtgaaagatttgtctggccgaccaaaggacatgcacggcatggacgtctggggccaagggaccacggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15844 JY8QFUQ01CDZI0 No results 15845 JY8QFUQ01DVPUO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKVLSGDFQRIMIRPFFDHW in-frame - gctctggattcacatttaacaactatgccatgatttgggtccgtcagggtccagggcgggggctggagtgggtctcagcaatcagtggttatggtggtaccacctacgccgcaaagtccgtggagggccggttcgacatttccagagacaactccaagaacacggtgtatctgcaaatgaacggcctgagggccgaggacacggccgtatattactgtgcgaaggtgttgtcgggagactttcaacggattatgataagaccgttctttgaccactggggccagggaacccagctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15846 JY8QFUQ01BZ9AE No results 15847 JY8QFUQ01APYBC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); cctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctatgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15848 JY8QFUQ01A3EA4 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15849 JY8QFUQ01C48PF No results 15850 JY8QFUQ01BR6QV productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctacattcacgGtttagtcggtattggatgagctggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttcttcgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15851 JY8QFUQ01CU8CL productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaTggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15852 JY8QFUQ01BEK4N productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15853 JY8QFUQ01CGQES productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 18 8.8.18 [1.17.38.11] CVRESGDYGGKYSKSYFDYW in-frame + cctctggattcactttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatcaattactagaagttctagttatatgtcctacgcagactcagtgaagggccgattcaccatctccagagacaatgccgagaattcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgagagaatcgggtgactacggtggtaaatatagcaagtcatactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15854 JY8QFUQ01BGLRM No results 15855 JY8QFUQ01A0GZB No results 15856 JY8QFUQ01CKWBK productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 932 92.2 201/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15857 JY8QFUQ01BB0A4 unproductive Homsap IGHV3-11*01 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD7-27*01 F 2 8 8 X 8.8.X [1.16.38.11] CARDLNG#DYW out-of-frame - in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctgaatccaccttcagtgactactacatgaactggtccgccaggctccagggaagggctggagtgggtttcatatattagtagtagtagtagtatcataacctacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgagagatcttaacggggggactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15858 JY8QFUQ01BP3BX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CSRHGGYTKLYNQNVYLDYW in-frame + tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccacctccagagacaactctagaaactcgctgtgtctgcaaatggacagcctgagagccgaggacacggctgtgtattactgttcgagacatggaggttacacgaaactctacaatcaaaatgtctaccttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctgtccagggcttgttcccc 15859 JY8QFUQ01C7G6G No results 15860 JY8QFUQ01C66GX productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaagactacttccccgaaccggtgacggtgtcgtggaactcag 15861 JY8QFUQ01BDX24 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame - tctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15862 JY8QFUQ01CW1BP productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcg 15863 JY8QFUQ01CDZHK unproductive Homsap IGHV3-33*03 F 932 92.2 201/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15864 JY8QFUQ01BRMK5 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFM#DYW out-of-frame - cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggacttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15865 JY8QFUQ01ARH9K productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15866 JY8QFUQ01DO7XU unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 914 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtGgggtgtcacgtantaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15867 JY8QFUQ01CD6FW No results 15868 JY8QFUQ01AHX53 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15869 JY8QFUQ01DCQQ3 productive Homsap IGHV3-30*01 F 996 95.0 209/220 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - ggcctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15870 JY8QFUQ01CJHJS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccaTgggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15871 JY8QFUQ01C3DAG productive Homsap IGHV3-7*01 F (see comment) 733 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 15872 JY8QFUQ01AD2NS productive (see comment) Homsap IGHV3-9*02 F (see comment) 733 82.41 178/216 nt 81.94 177/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 7 19 8.7.19 [1.17.38.11] CVKDKDKVGGHTGHYPTFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) ctctggattcaaccccgaaaactttgccatgcactgggtccgacaagttccagggaagggcctgaagtgggtctcaggtataaattggaatggacgaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccaatttggggactgaggacacggccttctatttttgtgtgaaagataaggacaaagtggggggccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15873 JY8QFUQ01CQJR7 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15874 JY8QFUQ01CSACT No results 15875 JY8QFUQ01BNRL4 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 7 17 8.7.17 [1.17.38.11] CARVVMATVYTGSYYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); tgtatggtgggtccttcagtgataactcctggacctggatccgccagcccccagggaaggggctggagtggattggagagatcaatcatagtggaaAacaccaactacaacccgtccctcaggagtcgagtaatcatgtcaatagacacgtccatgaaccaattctccctgaagctgacttctgtgaccgccgcggacacggctgtgtattattgtgcgagagtcgtgatggctacagtttatactgggtcctactactttgacgactggggccagggaaccctggtctccgtcttctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15876 JY8QFUQ01C41FF productive Homsap IGHV3-33*03 F 968 94.04 205/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 8 20 8.8.20 [1.17.38.11] CARDGDYYDSSGNFLGHSFDIW in-frame + cgtctggattcagcttcagtagttatggcgtgaactgggtccgccaggctccaggcaaggggctggagtgggtggctgttatttggtatgacggcaataataaatattatgcagactccgtgaagggccgattcaccatctccagagacgactccaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcgagagatggagattattatgatagtagtggtaatttcctgggacattcttttgatatctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15877 JY8QFUQ01A3I7J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [1.17.38.11] CATWIQSHFDYW in-frame + ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15878 JY8QFUQ01C7KSE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - cctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15879 JY8QFUQ01CLP4K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15880 JY8QFUQ01C1P51 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 101 53.08 69/130 nt 8 7 X 8.7.X [X.17.11.X] null - No rearrangement found stop codons ggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15881 JY8QFUQ01DGR27 productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15882 JY8QFUQ01BAJEK No results 15883 JY8QFUQ01AVJ1Q productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15884 JY8QFUQ01B5TTZ productive (see comment) Homsap IGHV3-7*01 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-26*01 F 3 8 8 8 8.8.8 [1.17.38.11] CVRERGGRYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'TAA' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'GAC' (3 nucleotides at position 36 to 38 in the user submitted sequence), (do not cause frameshift); cctctggattcacctttaatTAAcacatttggataGACattggggtccgccaggctccagggaaggggctggagttggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtatctgcaaatgagcagcctgagagccgaggacacggctatgtattattgtgtgagagagagaggggggaggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15885 JY8QFUQ01B4ZHH productive (see comment) Homsap IGHV3-30*01 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [2.17.37.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 211 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15886 JY8QFUQ01DKV8D productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15887 JY8QFUQ01B6ORR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); aggctctgacttGcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15888 JY8QFUQ01BZ10X productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcctctggattcaccCtttggttattatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacgGgccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15889 JY8QFUQ01CKE7Y productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15890 JY8QFUQ01AKAYX unproductive (see comment) Homsap IGHV3-11*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRGEKWELR##DHW out-of-frame - stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggGggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccagggtcaacgccaagaactcactgtctctgtaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaaagatcggggggaaaagtgggagctacggacttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15891 JY8QFUQ01C8J7S No results 15892 JY8QFUQ01CNEV5 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 37 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15893 JY8QFUQ01CQV6R unproductive Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRDSDSSASYFA#W out-of-frame + cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15894 JY8QFUQ01BAD49 unproductive Homsap IGHV4-39*02 F 938 91.86 203/221 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 10 7 X 10.7.X [1.17.38.11] CARLLRVYDWYSQRGLL#DTW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctccgatggctccatcagcactagtaattactactggggctgggtccgccagcccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaagggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgggtgtcgtggaactc 15895 JY8QFUQ01AZ65I productive Homsap IGHV3-9*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSGGYTHNYFDYW in-frame + ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagctggaatagtggtagtatagggtatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttgtattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatcctcgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15896 JY8QFUQ01B3FLS unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 189 60.0 81/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 15897 JY8QFUQ01ANTXC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + cctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15898 JY8QFUQ01ACXOG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 843 87.27 192/220 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ggcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15899 JY8QFUQ01B3YVR productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-61*02 F 957 94.39 202/214 nt 92.99 199/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 8 7 11 8.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CAGTAC' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); ctctggtgggtccatcagCAGTACtagttactactggagctggatccggcagcccgccgggaagggactggagtggatgggggCgtatctataccagtgggatcaccaactacaaccCcctccctcaagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgntccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 15900 JY8QFUQ01CQ04Z productive Homsap IGHV3-7*03 F (see comment) 766 83.56 183/219 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [2.17.38.11] CTRRGFMDVW in-frame - Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattgcaatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15901 JY8QFUQ01CDOX5 productive Homsap IGHV4-61*02 F 1010 95.48 211/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 10 7 15 10.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + tctctggtggctccatcggcagtggtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15902 JY8QFUQ01DPNH7 productive (see comment) Homsap IGHV3-72*01 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.16.38.11] CARLHYSGGWYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagatgactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15903 JY8QFUQ01DDH3H No results 15904 JY8QFUQ01DCRDZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgaGgctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15905 JY8QFUQ01BW1MW productive Homsap IGHV3-11*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDDSCSGGSCYEYW in-frame - acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15906 JY8QFUQ01CP7TZ No results 15907 JY8QFUQ01DIB2J No results 15908 JY8QFUQ01CN554 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 965 93.21 206/221 nt 92.76 205/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tctctggtgcctccgtcagcagtggtAgttttctactggacctggattcgtcagcacccagggaagggcctggagtggattgggtacatctattacagtgggagcgcctactacaacccgtccctcaagagtcgagttgccatatcaatagacacgtctaagaaccagttctccctgaacttgagttctgtgactgtcgcggacacggccgtttattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 15909 JY8QFUQ01BBY5Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame + cctctggattcacgtttagtagctatggcatgggctgggtccgtcagactccagggaaggggctggagtgggtctcaactattagtggcagtggtcggagcacatactacgctgactccgtgaagggccggtacaccatctccagagacaactccaagaacacggtgtctgtgcaaatgaacagcctgagagtcgaggacacggccgtttattattgtgtgaaaaggttggagggagtggctgatgatgcttttgatatctggggcccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 15910 JY8QFUQ01ATJH3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccGgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15911 JY8QFUQ01CRQE6 unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaacatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15912 JY8QFUQ01CAQ16 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15913 JY8QFUQ01CTYEK unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKK*GVGDG##WYFDFW out-of-frame + stop codons in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 88 to 90 in the user submitted sequence), (do not cause frameshift); cctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15914 JY8QFUQ01AKBD8 No results 15915 JY8QFUQ01AMBZM No results 15916 JY8QFUQ01BALS7 No results 15917 JY8QFUQ01B4U42 No results 15918 JY8QFUQ01CW89R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 781 83.78 186/222 nt 82.88 184/222 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [3.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); caatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15919 JY8QFUQ01ANMB1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 926 92.56 199/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 7 8 13 7.8.13 [2.16.38.11] CAKRRGGYYIDFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'AG' (2 nucleotides at position 122 to 123 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 3 nucleotides (from position 21 in the user submitted sequence), (do not cause frameshift)in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) gccactggattcacccttaactatgccataaattgggtccgccaggctccagggaaggggctgagtgggtctcaactatcaatactagtggtagtagcacatactacgcagactccgtgaaAGgggccggttcaccatctccagagacaattccaagaacgaggtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaagcggaggggtggttattacatcgactttgactactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15920 JY8QFUQ01CB9CI productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 990 95.39 207/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARGDGSGWSGVDVW in-frame - ctctggattcacctttgatgatcatggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtatttattgggatggtggtaatacaggttatgcaggctctgtgaagggccgattcaccatctccagagacaacgccaagaacttcgtgtatctgcaaatgaacagtctgagagccgaggacacggccttgtattattgtgcgagaggtgatggcagtggctggtccggtgtggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15921 JY8QFUQ01BJ694 unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 138 64.1 50/78 nt 8 X X 8.X.X [1.16.X.X] null + No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 15922 JY8QFUQ01CZKYQ No results 15923 JY8QFUQ01CVP6L productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame - Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15924 JY8QFUQ01BGN7G unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 89 58.57 41/70 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctggattccccatcagtggctttagaatgaacgtggtcgtcgcatgcctggtccagggcttcttcccc 15925 JY8QFUQ01CS8OP productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15926 JY8QFUQ01CT923 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 914 91.28 199/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + cctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctgctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15927 JY8QFUQ01AQQ5Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaAaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15928 JY8QFUQ01C5JDI No results 15929 JY8QFUQ01AWP5Q No results 15930 JY8QFUQ01CJ536 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15931 JY8QFUQ01B6JOD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 847 87.67 192/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - ctccggagttcaacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15932 JY8QFUQ01AOMNK productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15933 JY8QFUQ01BFYFA productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKAYDDVLTSYYIAAFIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgccatgcattgggtccgccaggctccaggcaaggggccggagtgggtggcagttatatcatatgatggaagtcataaagactatgcagcctccgtgaagggccgattcaccatctccagagacaattccaagagtacgttgtatctgcaaatgaacagcctgagacctgaggacacggctttatattcctgtgcgaaggcatatgacgatgttttgacttcttattacatagcagcttttattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15934 JY8QFUQ01CFRQV productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaAaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15935 JY8QFUQ01DPD3M productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15936 JY8QFUQ01DP9T6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 943 93.9 200/213 nt 93.43 199/213 nt 8 8 X 8.8.X [X.17.38.X] null - No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); acattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaAaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15937 JY8QFUQ01BQYCK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1027 96.8 212/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 8 8 8.8.8 [2.17.38.11] CAVNWNLDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagcggctatgccatgagctgggtccgccaggctccagggaaggggctggactgggtctcatctattagttataatggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctccaaatgaacagcctgagagccgaggacacggccgtatattactgtgctgtgaactggaaccttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15938 JY8QFUQ01A0G35 No results 15939 JY8QFUQ01DAKH7 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgcactGgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15940 JY8QFUQ01A2BDN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15941 JY8QFUQ01DMHOM unproductive Homsap IGHV3-48*01 F 1048 98.61 213/216 nt Homsap IGHJ6*01 F 189 77.78 49/63 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CVREGRGTGR#YGLDVW out-of-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccggccgcctacggtctggacgtctgggggccagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtnttccccctggcgccctgntccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15942 JY8QFUQ01BWC0Y unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.16.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggatgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagGactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15943 JY8QFUQ01DA9S4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtctcccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15944 JY8QFUQ01BJDJL No results 15945 JY8QFUQ01CNN3Q unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 153 91.67 33/36 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found tctggattcaccttcagtaattactggatgtactgg 15946 JY8QFUQ01CEQ58 productive Homsap IGHV1-3*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15947 JY8QFUQ01AIVJA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15948 JY8QFUQ01BZ1HL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 750 83.64 179/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15949 JY8QFUQ01DC2WW productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacccttctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15950 JY8QFUQ01B0T8V unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGF*LL# out-of-frame + stop codons ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 15951 JY8QFUQ01DIKEE productive Homsap IGHV3-72*01 F 926 90.62 203/224 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15952 JY8QFUQ01AW8IU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 18 8.8.18 [1.17.38.11] CVKDLAHITHSSPWDDFDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggcaggggctggtgtgggtctcacgcattaatgaagatggaagtatcgtaacctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgagcagtctgagagccgaggacacggctgtgtattactgtgtaaaagacctcgcccacattacacatagtagcccgtgggacgactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgcctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgccatgcctggtccagggcttcttccc 15953 JY8QFUQ01AUJFH No results 15954 JY8QFUQ01DJYHX unproductive (see comment) Homsap IGHV3-9*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAK*FWSVAGRT#FDYW out-of-frame + stop codons ctctggattcaagtttgatgattatgccgcgcactgggtccggcaagctccagggaagggcctggaatgggtctcaggtattagttggaatggtggtagcacacgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgccctgtatctggaaatgaacattctgagaactgacgacacggccttatattactgtgcaaaatgattttggtcagtggctggtcggaccttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15955 JY8QFUQ01B4EGF productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15956 JY8QFUQ01CJP71 unproductive Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.37.11] CARDGEQWLVWTL#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccgggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15957 JY8QFUQ01CKQY0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1012 90.95 221/243 nt 90.12 219/243 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [10.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); gggtccctgagactctcctgttcagcctctggattcatcttcagtgcctactggatgcactgggtccgccaagctccagggaaGggggctggtatgggtctcacgtactaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatggacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15958 JY8QFUQ01BYGN8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDLVVTSIGPQGIHGHW in-frame + ctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 15959 JY8QFUQ01B0TDL No results 15960 JY8QFUQ01APKQ3 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15961 JY8QFUQ01DJGT0 unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD2-15*01 F 1 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW# out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtcgtcgtggaactcag 15962 JY8QFUQ01DM0G8 productive Homsap IGHV3-30*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15963 JY8QFUQ01CJ44M No results 15964 JY8QFUQ01BR2G2 productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 15965 JY8QFUQ01A619F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15966 JY8QFUQ01DA5RR productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 15967 JY8QFUQ01C8NI1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15968 JY8QFUQ01B34XL productive Homsap IGHV4-39*03 F (see comment) 911 90.45 199/220 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 2 10 7 12 10.7.12 [1.17.38.11] YTREGPYYYGMDVW in-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccatcagtaatactgattactactgggtctggatccgccagaccccagggaagggactggagtggattgggagtatcgatttcagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccatagacacgtccgagaaccggttctccctgaggttgacctctatgaccgccgcagacacggccgtctattactatacgagagagggaccctactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15969 JY8QFUQ01BCB2R productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15970 JY8QFUQ01BLVTL productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 937 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-19*01 F 1 10 7 10 10.7.10 [1.16.38.11] CAAYDSGWYKHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctgagtggattgganacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtctaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15971 JY8QFUQ01CJZ1Y productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + tctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15972 JY8QFUQ01AEYN1 productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15973 JY8QFUQ01BBI8L productive (see comment) Homsap IGHV4-61*02 F 970 93.24 207/222 nt 92.34 205/222 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD5-18*01 F 3 10 7 18 10.7.18 [2.17.38.11] CARVRARSNSHPGHSWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'AC' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagcACgtaggttactactcgacctggctccggcagcccgccggaaagggaccggagtggaAttgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15974 JY8QFUQ01APCJA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15975 JY8QFUQ01AKMPH unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 932 96.5 193/200 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD6-13*01 F 2 3 8 X 3.8.X [X.17.38.11] CARGQQLRDFYY# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggcagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccgag 15976 JY8QFUQ01CPAF4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15977 JY8QFUQ01DMAVN productive (see comment) Homsap IGHV3-69-1*02 P (see comment) 917 92.09 198/215 nt Homsap IGHJ1*01 F, or Homsap IGHJ4*02 F (see comment) 126 75.56 34/45 nt Homsap IGHD7-27*01 F 2 8 8 6 8.8.6 [1.17.38.11] CARVEMDW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01DMAVN ; 7 AA in Homsap_IGHV3-69-1*02) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtgactataccatgaactgggtccgccaggctccagggaagggtctggagtgggtctcgtccattagtagtagtggtgattccatatactacgcagactcggtgaacggccgattcaccatcaccagagacaacgccaagaattcactttttctgcaaatggacagcctgagagccggggacacgggtgtttattactgtgcgagagttgaaatggactggggccagggaaccccggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 15978 JY8QFUQ01AUSQG productive (see comment) Homsap IGHV3-11*01 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.16.38.11] CARDDSCSGGSCYEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 53 of V-REGION: 2 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) ctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggaggggcgtggagtggttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15979 JY8QFUQ01C8PPE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggGggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactgggggccaggggagccctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15980 JY8QFUQ01B471O productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15981 JY8QFUQ01C91CD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15982 JY8QFUQ01AH1CO No results 15983 JY8QFUQ01CICCB unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKNQQ*LR*##DWFDPW out-of-frame + stop codons in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccaggggcttcttccccccgag 15984 JY8QFUQ01DFJK6 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [0.17.38.11] CARDRRGYSYEMDYW in-frame - ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15985 JY8QFUQ01CU4YF productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCCA' (7 nucleotides at position 84 to 90 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacggGgcccctggacaAagggcttgagtggatgggatggatcaAACCCCAaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15986 JY8QFUQ01APCV8 No results 15987 JY8QFUQ01A7E8X No results 15988 JY8QFUQ01CE8U8 productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 15989 JY8QFUQ01CA87L productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 834 88.63 187/211 nt 88.15 186/211 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 1 8 7 20 8.7.20 [X.17.37.11] CVRDGRRTYNSGWYSLAAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 152 in the user submitted sequence), (cause frameshift) tgtctgccatcagcagtggtaactggtggagctgggtccgccagcccccagggaaggggctggaatggattggagaaatctcttatagtgggaccaccaagtacaaccggtccctcaagagtcgagtcaccatatcactagacacgtccaaaaccatttctccctgcagctgacttctgtgaccgccgcggacacggctgtctattattgtgtgagagatggtcgccggacctataacagtggctggtattcgttagctgcttttgatatctggggccaggggacagtggtcaccgtctcttccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 15990 JY8QFUQ01A58RQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca 15991 JY8QFUQ01APMPL unproductive (see comment) Homsap IGHV4-55*01 P, or Homsap IGHV4-55*02 P or Homsap IGHV4-55*03 P or Homsap IGHV4-55*04 P or Homsap IGHV4-55*05 P (see comment) 233 55.8 125/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 1 8 7 X 8.7.X [4.17.38.11] SCERHWTNLRSGP#LDYW out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01APMPL ; 9 AA in Homsap_IGHV4-55*01), and low V-REGION identity (55,80% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccataaaataggggtaattattactggaactggatccggcagccccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaaccccgtccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttcgtgcgagagacactggacaaacctacggtcggggcccatttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 15992 JY8QFUQ01CODK0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.91 200/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctcctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15993 JY8QFUQ01CABWW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 15994 JY8QFUQ01DDTZN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 15995 JY8QFUQ01CAC3H No results 15996 JY8QFUQ01BZFIE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 15997 JY8QFUQ01BCW8A No results 15998 JY8QFUQ01BL0H6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 15999 JY8QFUQ01CE2FS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16000 JY8QFUQ01DIG6K unproductive (see comment) Homsap IGHV3-7*01 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); cgacctctggaGTtcaacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16001 JY8QFUQ01DBFVZ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 117 80.56 29/36 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found cctctggattcacctctcctagatactggatgaatt 16002 JY8QFUQ01AOPRK unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGVIV#DYW out-of-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgaactc 16003 JY8QFUQ01AM5PU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16004 JY8QFUQ01AHQN6 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 771 83.64 184/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARQSEPANNFNDPSRYFFDTW in-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctcccgtgtctccatttccattaatgattactactggggctggatccgccagcccccaggaaagccgctggagtggattgggactgtccattcccttgggtacaattacaacaacccgtccctcaagagtcgactcaccatttccgcagacacgtccaggaatcagatctccctgaaactgacgtctgtgaccgccgcagacacggctgtctatttctgtgcgagacagagcgagcccgccaataacttcaatgacccaagtcgttatttctttgacacttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16005 JY8QFUQ01AS7A3 No results 16006 JY8QFUQ01B7UKD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [0.17.38.11] CAKDLVVTSIGPRES#GHW out-of-frame - in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); ctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtGgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggccccagggaatccatggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16007 JY8QFUQ01BMX9G productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagCcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 16008 JY8QFUQ01B3S4F productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 991 94.98 208/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagGtagctactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16009 JY8QFUQ01C3ZVN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - tctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16010 JY8QFUQ01DQTXA No results 16011 JY8QFUQ01A8QCW productive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16012 JY8QFUQ01B7KE2 No results 16013 JY8QFUQ01A8OIE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-23*01 ORF 2 7 7 8 7.7.8 [2.17.38.11] CAGHGGSSHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) gcctctggattctccctgagggcaatggcatgagctgggtccgccaggctccagggaagggactggaatgggtctcagatataattggtagtggtgacacattctacgcagaatccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtacttgcaaatgaagagcctgagggccgaggacacggccgtatattattgtgcgggtcatggtggaagttcccactggggccagggaaccctggtgaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16014 JY8QFUQ01A16J5 unproductive (see comment) Homsap IGHV3-38*01 ORF, or Homsap IGHV3-66*02 F (see comment) 722 82.55 175/212 nt 81.13 172/212 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-8*01 F 1 8 6 X 8.6.X [1.17.38.11] CARHLMVYALDV## out-of-frame - stop codons Low V-REGION identity (82,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'TCT' (3 nucleotides at position 80 to 82 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'G' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaGggggctggagtgggtctcagTCTtatttagtactggcactgcatactacgcagactccGtgaaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16015 JY8QFUQ01C4MC9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16016 JY8QFUQ01DAM0C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16017 JY8QFUQ01A0DA8 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame - ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 16018 JY8QFUQ01CNZ0L No results 16019 JY8QFUQ01BIEP0 productive Homsap IGHV3-9*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD6-13*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARKGGSNGRTWYNWFDPW in-frame - ctctggattcacctttaataattatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagtggtagtatagcgtatgcggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaattgaagacacggccttttattactgtgcaagaaagggaggaagcaatggcaggacctggtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16020 JY8QFUQ01CYS8I productive Homsap IGHV3-9*01 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + tctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16021 JY8QFUQ01BLRPP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16022 JY8QFUQ01C3DOE productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - tccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16023 JY8QFUQ01AO5H2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-6*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAKVDSSSAWDYW in-frame + Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaagtttcatgaatatgccatgatctgggtccgccaggctccaggcaagggtccggaatgggtctcgtctattagtagtactagtaaatacatctattatgcacagtcagtggagggccgattcaccatctccagagacgacgccgagaacgcactgttcctccagatgagcagcctgagtgtcgacgacacggctatctattactgcgcgaaagtcgatagcagttcggcctgggactattggggcccgggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16024 JY8QFUQ01CGLR6 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 16025 JY8QFUQ01C3W7S No results 16026 JY8QFUQ01CC4O1 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16027 JY8QFUQ01B8DLI productive Homsap IGHV3-7*01 F 881 90.23 194/215 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [0.17.38.11] CARVIPGRGNYAFDVW in-frame - ctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggttcagggcttcttccccca 16028 JY8QFUQ01DKEJD unproductive Homsap IGHV3-72*01 F 1038 96.41 215/223 nt 95.96 214/223 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CVRGLHSNYYGMDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggGggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcagggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16029 JY8QFUQ01AZPWT No results 16030 JY8QFUQ01C0TGG productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16031 JY8QFUQ01C9JN3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccgggtgacggtgtcgtggcaactcag 16032 JY8QFUQ01DAT2D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16033 JY8QFUQ01ARS0N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16034 JY8QFUQ01BT5YI productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 17 8.7.17 [1.16.38.11] CARVVTATIYTGSYYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tctatggtgcgtccttcagtgattactcctgggcctggatccgccagtcccagggaaggggctggagtggattggagagatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgaggcatcatatcaatagacatgtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtatattactgtgcgagagtcgtcacggctacaatttatactgggtcctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16035 JY8QFUQ01CM3TN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16036 JY8QFUQ01APJNE unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 898 91.55 195/213 nt 90.61 193/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD2-21*01 F 3 8 7 X 8.7.X [1.17.38.11] CTRELRLAAARDGVDI#W out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); tctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggGAaaggggctggagtGgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacattttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16037 JY8QFUQ01B44GL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKLGVAATTWNFFDYW in-frame + ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16038 JY8QFUQ01BLXM5 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 2 8 7 16 8.7.16 [2.17.38.11] CVRYDYSRLHRSNYFGPW in-frame - gcctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtattacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16039 JY8QFUQ01BVJIX productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16040 JY8QFUQ01ATFZ4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgacaagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16041 JY8QFUQ01CT2LU productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1015 95.5 212/222 nt 94.59 210/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 2 7 10 10 7.10.10 [1.17.38.11] CTTLPWEPLDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtatgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaactagaactgatggtgagacaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcGaaaaaacacgttgtttcttcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtaccactcttccttgggagcctctcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaactggtcatcgcctgcctggtccagggcttcttcccccag 16042 JY8QFUQ01B6GM0 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 953 91.96 206/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 10 14 8.10.14 [1.17.38.11] CVVDIPEVGVGEFDYW in-frame - cctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttggtgtgggggaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16043 JY8QFUQ01B7UDZ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 111 56.19 59/105 nt 8 8 X 8.8.X [1.17.X.X] null + No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16044 JY8QFUQ01CJVPB productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 669 79.44 170/214 nt 78.97 169/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 208 to 208 in the user submitted sequence), (cause frameshift); ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacataCtttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16045 JY8QFUQ01A1V6B productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD1-20*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRKKSLDIWFDPW in-frame - ctctggattccccttcagtgatttctacatgatgtggatccgccaggctccagggaaggggctggagtgggtttcacacattagtggtagtggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaaatcactgtttctgcaaatgaacagcctgaaagtcgaggacacggccgtctatttctgtgcgagagtccgcaaaaaatcattggacatctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16046 JY8QFUQ01BRJTL unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 883 89.5 196/219 nt 89.04 195/219 nt Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [2.17.38.11] CAANLGHGSYF##IG out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ1*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); gtctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaaaggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctctTtttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattgggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16047 JY8QFUQ01AMIC0 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 972 94.47 205/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD3-22*01 F 3 9 7 11 9.7.11 [1.17.38.11] CAGLLTTFGLQSW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccatcagcagtagtaactggtggacttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatggtggaaacacctactacaacccgtccctcaagagtcgagtcaccatatcactagacaagtccaagaaccaattctctctgaacctgaactctgtgaccgccgcggacacggccatatattactgtgcgggacttcttacgacttttggactgcagagctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccc 16048 JY8QFUQ01ACK3W unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 644 77.06 168/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtggcggtgtcgtggaactcag 16049 JY8QFUQ01AKB5X productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16050 JY8QFUQ01CXD17 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTREWSGIDYW in-frame - ctctggattcattttcagtaactactggatgcactgggtccgccaagctccagggaaggggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16051 JY8QFUQ01AFKT3 productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F (see comment) 151 78.0 39/50 nt Homsap IGHD3-16*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARATNADVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccgagacctcactctatttgcaaatgaacaccctgagagccgaagacacggctgtctattactgtgcgagggcgactaatgccgacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16052 JY8QFUQ01C6P02 productive Homsap IGHV3-48*01 F 1009 95.89 210/219 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARVGATLSFDVW in-frame - gcctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16053 JY8QFUQ01B1RUY productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 795 85.51 183/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [0.17.38.11] CVRVRDYEIGGDFW in-frame + tggaggcgccttcagcacctttcatatcacctgggtgcgacaggcccctggacaagggcttgtctggctggggaatatcattcctatttttggaacagtcgactacgcacgggggttccagggcagagtcacgattaccgcggacgaatccaccaacacagcctacatggagttgagcagcctgacatctgaggactcagccgtctatttctgcgtgagagttcgtgactatgaaattggtggtgacttctggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 16054 JY8QFUQ01CR2E2 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 16055 JY8QFUQ01CO9IL productive (see comment) Homsap IGHV3-11*01 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREYSSGEKGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaatacctactacatgacctggatccgccaggctccagggaAaggggctggagtgggtttcacacattagtagtagtggcagtgtcacatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgagggcacggccctgtattattgtgcgagagaatacagtagtggtgaaaagggctggttcgacccctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 16056 JY8QFUQ01B58AR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16057 JY8QFUQ01A5L2A No results 16058 JY8QFUQ01BRCWZ productive (see comment) Homsap IGHV4-4*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtggctccataagaagttactactTggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 16059 JY8QFUQ01B6DIE No results 16060 JY8QFUQ01BOL9F productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16061 JY8QFUQ01CFH99 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16062 JY8QFUQ01AYOAK unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPTFMI (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16063 JY8QFUQ01DOV01 unproductive Homsap IGHV3-21*04 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 102 66.67 34/51 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CARAVSHQVDV## out-of-frame - Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ2*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaAGggggctggagtgggtctcatccattagAttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaagggggccacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 16064 JY8QFUQ01A9F0X productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 865 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 6 13 10.6.13 [1.16.38.11] CARQLSGDYASFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 99 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtggttggcaatatctattctagtggtgtcgctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16065 JY8QFUQ01BBWH9 productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + cctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16066 JY8QFUQ01AO0HA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16067 JY8QFUQ01DC1CW No results 16068 JY8QFUQ01COVW1 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame - tctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16069 JY8QFUQ01C1E4X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [1.17.38.11] CLKDHRGNYFDHW in-frame + ctctggattcgcctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtattagcgcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtttctgcaaatggacagcctgagagtcgaggacacggccatatattactgtctgaaagatcatagagggaactactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16070 JY8QFUQ01CAQGF No results 16071 JY8QFUQ01BGO58 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16072 JY8QFUQ01AXXC6 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDQRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcagcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16073 JY8QFUQ01CQHHK productive Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16074 JY8QFUQ01A39KY productive Homsap IGHV1-69*08 F 930 92.99 199/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame + tggaggctccttcggcagctacactatcacctgggtgcgacaggcccctggacaagggcttgagtggatgggaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 16075 JY8QFUQ01DE7IJ No results 16076 JY8QFUQ01BL7SM productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16077 JY8QFUQ01DBWV7 unproductive Homsap IGHV3-64*02 F 958 93.98 203/216 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CVTCGDYSYEY## out-of-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16078 JY8QFUQ01A04CF No results 16079 JY8QFUQ01AYPNE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactCccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16080 JY8QFUQ01CHYFI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVPGEHHSYYYGMNAW in-frame - gcctctggattcatctttactaactatgccatgagttgggtccgccaggctccagggagggggctggagtgggtctcaactatcagtgccaatggaggcaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaactccaagaacacagtggatatgcaaatgaacagcctgaaagccgaggagacggccgtctattattgtgcgaaagtcttccaggtgcctggcgaacatcactcctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16081 JY8QFUQ01CB319 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16082 JY8QFUQ01B6P06 productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16083 JY8QFUQ01CG4JW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNEFGYCSGG# out-of-frame - gctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16084 JY8QFUQ01AJYWV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16085 JY8QFUQ01BMEAE productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16086 JY8QFUQ01CD50L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16087 JY8QFUQ01APOZ1 productive (see comment) Homsap IGHV3-7*01 F 798 85.0 187/220 nt 84.55 186/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARERSAAGVVFFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); agcctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagAtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16088 JY8QFUQ01BI3TS productive Homsap IGHV3-7*03 F 882 89.86 195/217 nt Homsap IGHJ6*03 F (see comment) 147 76.47 39/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcacctttagtaaccattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16089 JY8QFUQ01C7GQS productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16090 JY8QFUQ01B0KON productive Homsap IGHV3-7*01 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - gcctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16091 JY8QFUQ01C2QWE productive (see comment) Homsap IGHV3-72*01 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 10 13 8.10.13 [1.17.38.11] CVRGLHSNYYGMDVR in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgaccactacatggactgggtccgccaggctccagggaaggGggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcaggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16092 JY8QFUQ01AK0GH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKVGGDVRSRPH*LL# out-of-frame - stop codons ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtggggggtgatgtccgctcgagaccgcattgactactgggggccgggaaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16093 JY8QFUQ01B9Q0Q productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + cctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16094 JY8QFUQ01B25CZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatcccccgaccagccccctaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16095 JY8QFUQ01B0SLO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 930 92.99 199/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [0.17.38.11] CARHEGYNSRYYYFGYW in-frame + tggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16096 JY8QFUQ01AG2CI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16097 JY8QFUQ01BO5PG productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggacCtggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16098 JY8QFUQ01BQ0GT productive (see comment) Homsap IGHV3-9*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ2*01 F (see comment) 157 77.36 41/53 nt Homsap IGHD4-11*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CARAPSVTFSGQGHYYDLW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); gcactggattcagctctgagaattatgccatgcactgggtccggcagcctccaCgggaagggcctagagtgggtctcacacatcagttggaatggcgaaggcatcgactacgcggactcagtgaagggccgattcaccgtctccagagacaacggcaagaattccctgtatttgcaaatgaacagtctgacaactgacgacacggccttgtattactgtgcaagagccccttcagtcacattcagcgggcaggggcactactatgatctctggggccgtggcaccctggtcgtggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16099 JY8QFUQ01BV2T6 unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 764 84.19 181/215 nt Homsap IGHJ4*02 F (see comment) 105 68.75 33/48 nt Homsap IGHD3-16*02 F 1 8 7 X 8.7.X [1.17.38.11] CARGPGSGSNSYYFGLL# out-of-frame + Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) tttatggtgcctccttcagcggacactactggggttggttccgccagcccccagggaaggacctggagtggatcggggaagtcagtcatggcggaagcatcaagttcaacccgtccctcaagagccgcgtcaccatgttagtagacacgtccacgagccgggtttctctgaggctgaccgctgtcaccgccgcggacacggctatgtattactgtgcgaggggcccaggttcggggagtaatagttattattttggattattggggcccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaactcag 16100 JY8QFUQ01BFY14 No results 16101 JY8QFUQ01C1H7H unproductive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CASRLRSSG#YW out-of-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 16102 JY8QFUQ01ARSU8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16103 JY8QFUQ01BFEPW productive (see comment) Homsap IGHV1-69*08 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); tggaggctccttcggcagctacactatcacctgggtgcgacaggcccctggacaagggcttgagtggatggGgaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16104 JY8QFUQ01AVYXK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.17.38.11] CARDTLEVVSNMDDAFDFW in-frame - gcctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagggcttggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16105 JY8QFUQ01CPL1S productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGataattttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16106 JY8QFUQ01AUJE9 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16107 JY8QFUQ01AZ3Q8 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 8 7 12 8.7.12 [1.17.38.11] CARAPGWMNPFDFW in-frame - ctccggtggctccatcaccacttactacatcagctggctccggcagcccccagggaagggactggagtggattgggtgtatctcttatggtggggacactacctacaactcctccctcaagagtcgagtcaccatatcaggacaagggtccacgcgccagttctccctgaggctgagctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16108 JY8QFUQ01DA9VQ productive (see comment) Homsap IGHV3-7*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtcccaggggcttcttcccccag 16109 JY8QFUQ01CY2CV productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagcagtagttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16110 JY8QFUQ01AHHJ6 productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16111 JY8QFUQ01CRSIV productive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctggtttcaccttcaggagctctggcatgaactGgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16112 JY8QFUQ01BQ3I3 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAKEEFDTGWTQPGDW in-frame - ctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16113 JY8QFUQ01COJUU productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 823 85.33 192/225 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD4-17*01 F 3 10 9 17 10.9.17 [1.17.38.11] CAREETTRPPSYYKGLDVW in-frame - tccggggacagcatttctagtaagacagctgcttggaattggatcagacagtcctcatcgagaggccttgaatggctgggaagggcatattacaggtccaagtggtataatgaatatggagaatctgtgaagggtcgcataacgttcagtggagacacatcgacgaatcagttctccctgcacctggactctgtgactcccgacgacacggctgtctatttctgtgcaagggaggagactacacgtcccccctcgtattacaaaggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16114 JY8QFUQ01DO25D productive Homsap IGHV4-30-4*07 F, or Homsap IGHV4-31*01 F or Homsap IGHV4-31*02 F or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F or Homsap IGHV4-31*06 F or Homsap IGHV4-31*07 F or Homsap IGHV4-31*08 F or Homsap IGHV4-34*09 F or Homsap IGHV4-59*06 F (see comment) 248 75.0 69/92 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 X X 18 X.X.18 [X.X.30.11] CARSAYCGADCYSADYLQHW in-frame + Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccgtcagcaacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaaggtcttcccggctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 16115 JY8QFUQ01C7O89 No results 16116 JY8QFUQ01A6QIC No results 16117 JY8QFUQ01CDBW9 No results 16118 JY8QFUQ01BBA7A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggccactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 16119 JY8QFUQ01DE2P3 productive Homsap IGHV3-72*01 F 943 91.89 204/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 3 8 10 15 8.10.15 [1.17.38.11] CVRVVREGAVTTFFDYW in-frame - tctggattcaccttcagtgactattatatagactgggtccgccaggctccagggaaggggctggagtggtttggccgttctagaaacaaagtgaatagttacagtacagcatacgccgcgtctgtgagaggcagattcagcttctcaagagatgattcaaagaacgcactgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtgtattattgtgttagagtcgtgagggagggcgcggtgaccacattctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgaggcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccag 16120 JY8QFUQ01BI8MT unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRRGDGSGQ##DAFDIW out-of-frame - stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16121 JY8QFUQ01C2XG5 productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame + ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16122 JY8QFUQ01C4QBN productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-1*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDHFLQPGRDYYYGMDVW in-frame + cgtctggatttcccttcagaacccatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcagttatctggtgggatggaagtcagaaatactatgaagattccgtgaagggccggttcaccatctccagagacaattctaagaacacggtttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtgcgagagatcatttcctacagccggggcgagactactactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16123 JY8QFUQ01CGF0M No results 16124 JY8QFUQ01BPRAJ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaAaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcag 16125 JY8QFUQ01DKJKX No results 16126 JY8QFUQ01A3RQE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16127 JY8QFUQ01CUN7T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16128 JY8QFUQ01AOSX6 productive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16129 JY8QFUQ01A6H3Y No results 16130 JY8QFUQ01CVYKI productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARDPGPSTPWYYFDYW in-frame + ctctggattcaccgttaataatcattggatgagttgggtccgccaggctccagggaaggggctggagtggctggcctacataaactatgatggaactgtgaaatactatgtggactctgtgaagggccgattcaccatctccagagacagcgccaggaactcactgtctctgcaaatgaacagcctgagagtcgaggacacggctgtatactactgtgcgagagatcccgggccttcgaccccctggtactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16131 JY8QFUQ01BLBJQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGNYWGYYYDS## out-of-frame + gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaggggctggagtggatctcagaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttgggggcctgggaaccctggtcgccgtctcctcagcatcccctgaccagccccaaggtcttccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16132 JY8QFUQ01A6BZO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CTKDYPDGRLLNHVLPFFDTW in-frame - cctctggattcacgtttgacgactatgccatgagttgggtccgccaggctccagggaaggggccggagtgggtctcaggtattattcctaatagtcgtgacagacactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagagcacagtgtatctgcaaatgaacaacctcagaggcgaggacacggccgtatattactgtacgaaagactatccggacggccgcctgctaaatcacgtccttcccttttttgacacttggggcgagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16133 JY8QFUQ01AOQRW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 765 83.87 182/217 nt 83.41 181/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CAKVKGYGGNWFQPHFDRW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); ctctggattcaccttcggcagttataggatgagctgggtccgacaggcGtccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaattccaaggacacggtctatctgcagatgaacggcctgagagtcgaagactcggcccgttattattgtgcgaaagtgaagggctacggcggcaattggttccagcctcactttgaccgctggggccagggcaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16134 JY8QFUQ01CX2EQ productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 985 93.33 210/225 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame + tccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 16135 JY8QFUQ01BB9AK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagAcccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16136 JY8QFUQ01CZX8Z productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16137 JY8QFUQ01DMUAK productive Homsap IGHV3-9*01 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame - cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctagaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16138 JY8QFUQ01BUZ5L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16139 JY8QFUQ01CEDUW No results 16140 JY8QFUQ01BXDL3 unproductive Homsap IGHV1-3*01 F 961 94.84 202/213 nt 94.37 201/213 nt Homsap IGHJ2*01 F (see comment) 85 62.26 33/53 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [0.17.38.11] CARWNNDLDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccaggggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16141 JY8QFUQ01DK9VC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAMRFCGGPECYPYLDNW in-frame + Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggttcacattcagtaactactggatccactggatccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgattttgtggtggtcctgagtgctacccttatcttgacaactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16142 JY8QFUQ01ACBE5 No results 16143 JY8QFUQ01BCC5N unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD3-10*02 F 2 8 8 X 8.8.X [0.17.38.11] CARVRGR***RLLCRG##AMDVW out-of-frame - stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); tggatacaccttccccgaccactatgtacactgggtgcgacaggcccctggacaagggcttgagtggatgggacggatcaGgccctaacactggcggcgcacactatggacagaggtttcagggcagggtcaccatgaccagggacacgtccatcaccacagtctacatggaattgagcaggctgagtccggatgacacggccgtgtattattgtgcgagagttcgggggagatgatgatgacggttactatgtcggggaggacgctatggacgtctggggccaggggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16144 JY8QFUQ01CZBMT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16145 JY8QFUQ01CTTTK unproductive (see comment) Homsap IGHV3-9*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVKRSKGQQL#YYFENW out-of-frame - stop codons cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagtcagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16146 JY8QFUQ01B10W1 No results 16147 JY8QFUQ01AQSIL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 16148 JY8QFUQ01DRFNR No results 16149 JY8QFUQ01A975A No results 16150 JY8QFUQ01AXLKO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 8 16 8.8.16 [1.17.38.11] CVRYDYSRLHRSNYFGPW in-frame + tctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16151 JY8QFUQ01C2M15 No results 16152 JY8QFUQ01AI276 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16153 JY8QFUQ01BFHQW No results 16154 JY8QFUQ01BM5VS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16155 JY8QFUQ01CB28K productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16156 JY8QFUQ01AWMK6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 140 86.49 32/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatgtttaggaactatgccatgagttgg 16157 JY8QFUQ01C5MW0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16158 JY8QFUQ01CI7LR unproductive (see comment) Homsap IGHV3-48*01 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctggcttcagtttgagtacttataccatgaactgggtccgccaggctccaggaagggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16159 JY8QFUQ01ATDOT productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16160 JY8QFUQ01DW9YA productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt 97.36 221/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'G' (1 nucleotides at position 150 to 150 in the user submitted sequence), (cause frameshift); tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcGaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16161 JY8QFUQ01AOTQ3 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW# out-of-frame + in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaaccCcctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 16162 JY8QFUQ01BI2RW No results 16163 JY8QFUQ01ASBUA unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 16164 JY8QFUQ01AXDN2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 16165 JY8QFUQ01DA6VC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 762 83.18 183/220 nt 82.73 182/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tctctgtgactccatcagtagtactcattactattGggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16166 JY8QFUQ01CYF81 unproductive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARNTNYGGNSGDYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccaagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16167 JY8QFUQ01A6CSB productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame + ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16168 JY8QFUQ01AOKUM productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*07 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 914 91.28 199/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame - cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16169 JY8QFUQ01C2V0B productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 7 8 10 7.8.10 [1.17.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift)in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) tccggattcaccttagtagttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16170 JY8QFUQ01BGZU9 productive Homsap IGHV3-7*01 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 16171 JY8QFUQ01BTX33 No results 16172 JY8QFUQ01DFILC No results 16173 JY8QFUQ01DBH3Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgaAtagcacatactactcaaacAtccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16174 JY8QFUQ01DH6UA No results 16175 JY8QFUQ01C8PK9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagttatagGcatgaactGgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16176 JY8QFUQ01CZH3T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 824 86.7 189/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame - tctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16177 JY8QFUQ01B7PFH productive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcCcccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 16178 JY8QFUQ01DB4UP productive (see comment) Homsap IGHV3-7*01 F (see comment) 724 81.94 177/216 nt 81.48 176/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggGggccagagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16179 JY8QFUQ01A6SVN productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16180 JY8QFUQ01C2MY9 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16181 JY8QFUQ01AJHM4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTREWSGIDYW in-frame + ctctggattcattttcagtaactactggatgcactgggtccgccaagctccagggaaggggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgatttaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactattggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16182 JY8QFUQ01CJ5TF productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16183 JY8QFUQ01CH2BP productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDVTSESHFFALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16184 JY8QFUQ01CXWET productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16185 JY8QFUQ01AUQ2Z unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CATDGVGSTVKLMVMGPFDFR in-frame - stop codons in CDR1-IMGT at codon 35 of V-REGION: 'AAC' (3 nucleotides at position 18 to 20 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); ctctggattcgtcctttAACgaactgatgccatgggctgggtccgccaggctccagggaaggggttggagtGgggtctcatctattagtactagtgggactaactcatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagcaagcgctttatctgcagatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16186 JY8QFUQ01DA179 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 10 6 11 10.6.11 [1.17.38.11] CARSYGFSRFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 91 in the user submitted sequence), (cause frameshift) tctctggtggctccatcaccagtagtctttaccgctggggctggatccgccagtccccagggaagggcctggagtggatagggaatatctttatggtgggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16187 JY8QFUQ01AN2H8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgGggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16188 JY8QFUQ01C3KAU productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 874 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F (see comment) 188 78.69 48/61 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CAREGGRGYDMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcCatttatcactgataGggggtagtacccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16189 JY8QFUQ01B4Z8B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16190 JY8QFUQ01AMBFI unproductive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1044 98.16 213/217 nt 97.7 212/217 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-2*02 F 2 8 7 X 8.7.X [2.17.38.11] CARGGRRQLA##EYFQHW out-of-frame - stop codons in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); agcctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttaCtttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagggggtcggcgtcagctggcatactgaatacttccagcactggggccagggcaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16191 JY8QFUQ01A9E7L productive Homsap IGHV1-18*01 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt 8 8 8 8.8.8 [0.17.38.11] CARGDYFDHW in-frame + tggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16192 JY8QFUQ01ASGEG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 761 83.49 182/218 nt 83.03 181/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [2.16.38.11] CARDSALFGYARYDAMDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcacgtttggcagccacgccatgagctggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16193 JY8QFUQ01B1F9O productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagtttcagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16194 JY8QFUQ01AWUPN productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVEATVAFQYW in-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataggggaggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtggaagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16195 JY8QFUQ01DPHRY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame - agcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16196 JY8QFUQ01BYBO2 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 7 8 X 7.8.X [1.17.38.11] CARPGGDCLL*WW*#CYDPW out-of-frame - stop codons in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) ctctggattcagctcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccagggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16197 JY8QFUQ01C8UBY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16198 JY8QFUQ01CNQC8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctgaattcaccctcagtgactactacatgagctggatccgccaggctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16199 JY8QFUQ01B9GN0 productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 8 22 8.8.22 [2.17.38.11] CARGHFDYYGSGSYYRDLYYFDNW in-frame - gcctctggattcaccttcagtagttataagatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacatcagtggtagtagtactaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaatggcctgagagccgaggacacggctgtgtattactgtgcgagaggtcacttcgattattatggttcggggagttattatagggacttgtattattttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16200 JY8QFUQ01BF7CI No results 16201 JY8QFUQ01B5JGV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 900 90.78 197/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDMVSGPVLFGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatatcgtacgagggacgtagtgaagactatgcagactccgtgaagggccgattcgtcatctccagagacaactccaagaacaccctgtatctactaatgaacagcctgagaggtgaggacacggctgtttactactgtgcgaaagatatggttagcggacctgtcctcttcggtatggacgtctggggccacgggaccaaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16202 JY8QFUQ01DPLES unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt 94.95 207/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcacctttagaagctatgccatgagctgGggtccgccaggttccagggaaggGggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16203 JY8QFUQ01BY5NQ No results 16204 JY8QFUQ01A08XO productive Homsap IGHV4-61*01 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + ctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16205 JY8QFUQ01CMX1Z productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16206 JY8QFUQ01C9N4Z productive (see comment) Homsap IGHV1-3*01 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGEPLGGDYFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcacttcttatgctgtaaaactgggtcgccaggGcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagtttcagggcagagtcaccattaccagggacacatccgcggacacagtcttcatggagctgagcagtctaagatctgaagacacggctgtgtattattgtgcgagagatggggagccactgggaggcgactactttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16207 JY8QFUQ01AURES productive (see comment) Homsap IGHV1-2*02 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.37.11] CAKHPLRSTSGHSYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) tggatacatattcaccgAccttttatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcgggcagggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16208 JY8QFUQ01BLVJA productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgagacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16209 JY8QFUQ01BDJMP unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16210 JY8QFUQ01BC6Y9 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16211 JY8QFUQ01A7JXF productive (see comment) Homsap IGHV3-13*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); agcctctggattcacgGttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16212 JY8QFUQ01B7R7S productive Homsap IGHV3-11*01 F 828 87.1 189/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - ctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 16213 JY8QFUQ01BMPPT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16214 JY8QFUQ01DQ7TD unproductive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDKGWSGYGMDV## out-of-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16215 JY8QFUQ01CYLZC productive Homsap IGHV1-69*08 F 930 92.99 199/214 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDSNGYSSGYIDCW in-frame + tggaggctccttcggcagctacactatcacctgggtgcgacaggcccctggacaagggcttgagtggatgggaaggatcacccctatccttggttcaacaagctactcacagaagttccagggcagagtcacgattaccgcggacacattcacgggcacagcctacatggagctgagcagcctgacatctgaagacacggccgtatattactgtgcgcgagactcgaatggatacagttctggttatattgactgctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagtctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 16216 JY8QFUQ01AWLNY productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1034 93.99 219/233 nt 92.7 216/233 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 10 9 19 10.9.19 [3.17.38.11] CARASRRDRQSDRNYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 26 of V-REGION: 'C' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); gtgccatcCtccggggacagtgtctctagcaacagtgccacAttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaGggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtcagtctgatcggaactactatgagctggacttctggggccagggaatcttggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16217 JY8QFUQ01CGUO4 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARIWDSWSGAFDV## out-of-frame + Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtgggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggacgtggtcatcgcctgcctggtccagggcttcttccccc 16218 JY8QFUQ01B34QT productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-9*01 F 3 8 7 19 8.7.19 [1.17.38.11] CAKVLSGDFQRIMIRPFFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctacCtggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgaaggtgttgtcgggagactttcaacggattatgataagaccgttctttgaccactggggccagggaacccagctcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16219 JY8QFUQ01CABXM productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 214 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16220 JY8QFUQ01C4HDT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 89 51.88 69/133 nt 8 6 X 8.6.X [1.17.12.X] null + No rearrangement found ctctggattcaccttcagctcccattggatgagctgggtccgccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16221 JY8QFUQ01DG1D7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 289 58.9 129/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (58,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gcctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggcgttggtgcttactacatctactattttgacttatgggaccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16222 JY8QFUQ01A72BF productive (see comment) Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGAYWNLIRDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 111 to 122 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 16223 JY8QFUQ01B1B9K unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16224 JY8QFUQ01CUD8G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16225 JY8QFUQ01AODUI productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 937 92.24 202/219 nt Homsap IGHJ6*02 F (see comment) 205 83.05 49/59 nt Homsap IGHD5-24*01 ORF 3 8 8 11 8.8.11 [2.17.38.11] CARPRYGYGLDVW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ggttctggatacgactttaacaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatcatctttcctggtgactctgatatcagatatagtccgtcgttccaaggccaggtcaccatctcagtcgacaagtccatcggcaccgcctacctgcaatggagcggcctgaaggcctcggacaccgccacttattattgtgcgagacctagatacggatacggcttggacgtctggggccaagggaccacggtcaccgtctcctcagccccccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16226 JY8QFUQ01CAJ7U No results 16227 JY8QFUQ01BBMOA unknown (see comment) Homsap IGHV3-15*08 F, or Homsap IGHV3-30*14 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*03 F 101 54.81 57/104 nt X X X X.X.X [X.X.34.X] null + No rearrangement found ctctggattcaccgtcagttccaatctccagcgacttttccaaggaaactctgtctcttcaagaaatagacctgaaaattgacgacacgccgagccgtttctagtgtagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16228 JY8QFUQ01DOQOV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame + ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 16229 JY8QFUQ01C4GEG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16230 JY8QFUQ01BOVRG productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + tctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16231 JY8QFUQ01CDJ5P unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 854 88.84 191/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD5-18*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGGIYL*Q#PW out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01CDJ5P ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccatcagcggcagtaccaactactggacctggatccggcagcccccaggaaagggactggaattcattgggtatatctataacagtggcaacaccaactacaacccctccctcaagagccgagtctccatttctttggacaggtccaagaaccagttctccctgaggctgacccccgtgaccgctgcggacacggccatgtattactgtgcgagggggggcatatacctatgacagcccgtggggccagggaacccgggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16232 JY8QFUQ01CHVZZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKQTIFDYYYYG#LDVW out-of-frame + Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggttttggacgtctggggtcaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16233 JY8QFUQ01A4HT0 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 2 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggagggggctggagtgggtctctggtattaatcggaatggtgatagcaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16234 JY8QFUQ01BGNLQ No results 16235 JY8QFUQ01AD4IM unproductive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGW*##DLDYW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); acctctggaGTtcaccctttagtaaccattGggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16236 JY8QFUQ01BZ7HA No results 16237 JY8QFUQ01C6C9B productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1078 98.65 219/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 10 7 13 10.7.13 [2.17.38.11] CARHSSVTTFPIDYW in-frame - gtctctggtggctccatcagcagtagtggtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaacctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacatagttcggtgactaccttcccgatcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16238 JY8QFUQ01BX7AZ unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16239 JY8QFUQ01A7OMB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16240 JY8QFUQ01BL1OC unknown (see comment) Homsap IGHV4-61*02 F (see comment) 566 78.07 146/187 nt 10 7 X 10.7.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactccattaccagtggtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctc 16241 JY8QFUQ01B8DVS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ1*01 F (see comment) 133 74.0 37/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'ATTT' (4 nucleotides at position 101 to 104 in the user submitted sequence), (cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaGggggctggagtgggtctcaagtgtcagtagtagtactggttATTTtcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16242 JY8QFUQ01CUKGG productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactttgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16243 JY8QFUQ01C0PJ7 No results 16244 JY8QFUQ01B4F8S unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 120 51.98 92/177 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccgaccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16245 JY8QFUQ01BRF2O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYSFDYW in-frame + cctctgggttcacctttgcccactttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtggtgatgattccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactcctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 16246 JY8QFUQ01A8LJ2 productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 840 88.32 189/214 nt Homsap IGHJ2*01 F 211 88.68 47/53 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [0.17.38.11] CATGADTGPNYWHFDLW in-frame - tggaggcaccttcagcaaccatgcgatcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcatccctcagtatggtgcagcaaactccgcactcaagttccacggcagaatcacgatgaccgcggacaaggccacaaacacagtctatatggaactgagcagcctgaaacctgacgacacggccgtctattactgtgcgactggtgcagacacgggcccaaattactggcacttcgatctctggggccgcggcacccgagtcacggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16247 JY8QFUQ01DFBH2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggAagtgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctggggctcctggtcaaggactanttcccccgaaccggtgacggtgtcgtggaactc 16248 JY8QFUQ01DNOGV No results 16249 JY8QFUQ01BCTAE productive (see comment) Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt 81.11 176/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 16250 JY8QFUQ01A572P productive (see comment) Homsap IGHV3-30*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctagattcaGccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16251 JY8QFUQ01DFNIJ No results 16252 JY8QFUQ01C3CF2 unproductive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVG#FDNW out-of-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatatggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16253 JY8QFUQ01AJ72N No results 16254 JY8QFUQ01CKYUM unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttaTacttaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16255 JY8QFUQ01B93IE No results 16256 JY8QFUQ01DP6MP unknown (see comment) Homsap IGHV3-7*01 F 1021 96.76 209/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 16257 JY8QFUQ01DV8ST No results 16258 JY8QFUQ01AL2ZX No results 16259 JY8QFUQ01BM7KL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 677 80.19 170/212 nt 79.72 169/212 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD1-1*01 F 2 7 8 X 7.8.X [X.17.38.11] CATARTGPGTSIYLTAY## out-of-frame - Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); gccctggattcaacaaatatggcatgagttgggtccgtcaggctccgggggagggtctaaagtgggtctcaactattagtgatagtactggtcgcacatactactcagactctgttaagggccgcttcAaccgtctcctgggacacctccaaaaacacgttgtatctgcaaatgaaaaacctcagagtcgaagacacggccgtttattattgtgcgacagcccgcaccgggcctggaacctcgatttatctcacggcctattgggggccagggaacccgagtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 16260 JY8QFUQ01AVZ9C productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [0.17.38.11] CARGDGYNFGGLDYW in-frame - ctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 16261 JY8QFUQ01DL5YY No results 16262 JY8QFUQ01DRFH2 No results 16263 JY8QFUQ01B771N No results 16264 JY8QFUQ01AX4YV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16265 JY8QFUQ01BJBUY No results 16266 JY8QFUQ01BX01L productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDWPSSGWSHFEAW in-frame + cctctggattcacctttgatgagcatgccatgcactgggtccggcaagttccggggaagggcctggagtgggtctctggtgttacttggaatagtggtgtcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaggaattccctgtatctacaaatgaacagtctgagaactgatgacacggccttctatttctgtgcaaaagattggccgagcagcggctggtcccattttgaggcttggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtnatcgcctgcctggtccagggcttcttcccccca 16267 JY8QFUQ01A80UX unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16268 JY8QFUQ01ADH46 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16269 JY8QFUQ01CMMJX productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16270 JY8QFUQ01CWR2N No results 16271 JY8QFUQ01C5489 unproductive Homsap IGHV3-48*02 F 981 94.47 205/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASIFWSGSPG##YYYGMDVW out-of-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgcgcctcgattttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16272 JY8QFUQ01A8FJO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 993 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARPGVGASSFIDFW in-frame + tggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16273 JY8QFUQ01DGOV6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 823 95.53 171/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatg 16274 JY8QFUQ01CZLD3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16275 JY8QFUQ01C7711 productive Homsap IGHV3-9*01 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + tctctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16276 JY8QFUQ01B6PCP productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 3 8 8 17 8.8.17 [0.17.38.11] CASLPGDLTQIQDGVFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggaggcaccttcgacagttatgttatcagctgggtgcgacaggCcccctggacaagggcttgagtggatgggcgggatcatccctatctttggttcggcaaagtatgcacagaagttccagggcagagtcaggattaccgcggacgaatccacgagcacggcctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgccagtcttcccggggatcttactcaaattcaagacggtgtttttgatatctggggccaggggacaatggtcagtgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 16277 JY8QFUQ01CU90A productive Homsap IGHV4-39*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16278 JY8QFUQ01CNDLU unproductive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSPQP#DPW out-of-frame - cctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattcccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16279 JY8QFUQ01B57Z7 unproductive (see comment) Homsap IGHV3-66*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-9*01 F 2 8 7 X 8.7.X [2.17.38.11] CARFVWADD##FDIW out-of-frame - stop codons in CDR2-IMGT at codon 59 of V-REGION: 'CG' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift); agcctctggactcaccgtcaatgtcaattacatgagctgggtccgccaggctccagggaagggtctggagtgggtctccactatttatagcCGgggggtgccacttactacgcagactccgtgaggggccgattcaccatctccagagccaagtccgagaatacactgtatcttcagataagcggtctgagacttgaggacacggctgtgtattactgtgcgaggtttgtctgggccgatgatgccttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16280 JY8QFUQ01CU1CP productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 16281 JY8QFUQ01CBP12 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD2-2*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKDPQQLLAEVNWFDPW in-frame - ctctggattcacttttagaagttatgccatgagttgggtccgccaggctccagggaaggggctagagtgggtctcatctatcagtggtaatggtgataagacaaagtacgcagactccgtgaagggccggttcaccatctccagggacaattttaagaatacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagatcctcagcagctattggcagaggtaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16282 JY8QFUQ01DABDC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 16283 JY8QFUQ01APICN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgaccgggtgtcgtggaactc 16284 JY8QFUQ01CLT2P unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16285 JY8QFUQ01AZU0Q productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 705 81.31 174/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatgggCctgggtccgccaggctccgggCaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16286 JY8QFUQ01BKTFU No results 16287 JY8QFUQ01CKX10 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 269 59.69 117/196 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (59,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16288 JY8QFUQ01A8A1Y unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.37.11] CAREKGSGPPN#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagcccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccaacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16289 JY8QFUQ01BWBAO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16290 JY8QFUQ01AUCPE productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16291 JY8QFUQ01BM9AS productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 773 83.04 186/224 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16292 JY8QFUQ01BH0QC unproductive Homsap IGHV3-9*02 F (see comment) 719 81.86 176/215 nt 80.0 172/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [0.17.38.11] CVKDKTKWGATLAIIP#FDFW out-of-frame - Low V-REGION identity (81,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 182 to 182 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); ctggattcaaccccgaaaaCtttagccatgcactgggtccgacaagttccagggaagggAcctgaagtgggtctcaggtataaattggaatggacgaaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccAattttggggactgaggacacGggccttctatttttgtgtgaaagataagacaaagtggggggccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16293 JY8QFUQ01CICS6 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16294 JY8QFUQ01BDUCL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 796 85.65 185/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + tctgggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcatttggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcaccctatatttacaaatgaatagcctgagagtcgaggacacggctgtgtattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16295 JY8QFUQ01ADGSX productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1001 97.17 206/212 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 7 8 11 7.8.11 [X.17.38.11] CARGQQLRDFDYW in-frame - gatacaccttcaccagctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16296 JY8QFUQ01B8QBH productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttTgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16297 JY8QFUQ01BW7NT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARVFSGVAAPPDSW in-frame + ctctggatttcccttcaccagttactggatgcagtgggtccgccaagctccagggaaggggctggtctgggtctcacttagtaatagtgatgggagcactactacctacgcggacgccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatcttcaaatgaatcatctgagagtcgaggacaccgctgtatatttctgtgcgagagttttcagtggtgtcgctgctcccccggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 16298 JY8QFUQ01DLIZU unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 905 90.83 198/218 nt 88.99 194/218 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 3 8 7 X 8.7.X [2.17.38.11] CARHSRLVRYFEF## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'AGCAAGGTG' (9 nucleotides at position 22 to 30 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 69 to 70 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 31 of V-REGION: 6 nucleotides (from position 21 in the user submitted sequence), (do not cause frameshift) ctgtctctggtggctccatcaAGCAAGGTGgtagttatcactgggcctggatccgccagtccccagggGAaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtGccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16299 JY8QFUQ01C84M1 productive (see comment) Homsap IGHV3-72*01 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.37.11] CTRDTTDTGGQSFNGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 97 of V-REGION: 3 nucleotides (from position 200 in the user submitted sequence), (do not cause frameshift) ctctggtttccccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaatcgaggacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16300 JY8QFUQ01AL1ZB unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CSKTPLGE#DYW out-of-frame - cctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtctcacgtattaatgaagatgggaggactacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacaccaagaacacactgtatctgcagatggacagtctgagagccgaggacacggctgtgtattactgttcaaagacacctttgggggagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 16301 JY8QFUQ01AMJTH unknown (see comment) Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 84 51.52 68/132 nt 8 10 X 8.10.X [2.17.9.X] null - No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16302 JY8QFUQ01B0CR7 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 16303 JY8QFUQ01BP1TQ productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggcg 16304 JY8QFUQ01AIVOZ productive Homsap IGHV3-30*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + ctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 16305 JY8QFUQ01ACYQ3 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1034 95.98 215/224 nt 94.64 212/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 9 9 19 9.9.19 [1.16.37.11] CARGSSRGGRSDVNYYELDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 34 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 80 of V-REGION: 1 nucleotides (from position 152 in the user submitted sequence), (cause frameshift) tctccggggacagtgtctctaccacagagctgcttgaactggatcaggcagtccccatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaaccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16306 JY8QFUQ01CWP59 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CAKDTITMAVTSLH#FDYW out-of-frame + cctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16307 JY8QFUQ01CESQP productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 3 8 8 16 8.8.16 [2.17.38.11] CARDHWAQHPAPHPFANW in-frame - gcctctggattcaccttcactagctatagtatgaactggctccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtggtactactgcatactacgcagactctgtgaggggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagggaccattgggcgcagcacccggcaccccacccctttgccaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16308 JY8QFUQ01CFYC2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16309 JY8QFUQ01DGRK1 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD1-14*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARDADTTTTSWYFD#LG out-of-frame - in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); gtccggattcagcctcagtagctatgGgcatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagatatttgggctgctggaaataagatttattatgcagactccgtgaagggccgattcaccatctccagagacaggtccgagaatacggtgtatctgcaaatgaacaacctgagagccgaggacacgggtgtatatttctgtgcgagagatgccgataccactaccacatcatggtacttcgatctctggggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccagg 16310 JY8QFUQ01AZ6Y2 No results 16311 JY8QFUQ01DNBYK No results 16312 JY8QFUQ01BFTW4 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 932 92.2 201/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcctctggattcaccCTttggttattgatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16313 JY8QFUQ01BH8QF No results 16314 JY8QFUQ01B74OP productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16315 JY8QFUQ01B0XLC unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*07 F or Homsap IGHV3-30*09 F 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttcattag 16316 JY8QFUQ01B0M6T productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16317 JY8QFUQ01C17DD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctacctggtccagggcttcttccccca 16318 JY8QFUQ01DPOHN No results 16319 JY8QFUQ01BHVC3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 484 82.86 116/140 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 16320 JY8QFUQ01BRA0B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [0.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ctggattcacCctttaacaactacgccatgtcctgggtccgccaggctccagggaAaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16321 JY8QFUQ01ABWX4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGIVGDTFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgAgatccccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16322 JY8QFUQ01CO4L4 productive (see comment) Homsap IGHV4-59*03 F 908 91.63 197/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GA' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 94 to 99 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagtTtggatgaggcagcccccagggaggggGActgggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16323 JY8QFUQ01BPT7N productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARNTPAYWELSGDW in-frame + ctctggattcacctttaggagttattggatcagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaacccagatggaagtgagaaatactatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgcgaaatacaccggcgtattgggaactatcaggtgactggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16324 JY8QFUQ01CXM4M productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 10 9 19 10.9.19 [1.16.38.11] CARASRRDRQSDRNYYELDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) ctccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacggaggccttgagtggctgggaaggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtcagtctgatcggaactactatgagctggacttctggggccagggaatcttggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16325 JY8QFUQ01CYGCX unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CTKDTFWER#DYW out-of-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgttttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16326 JY8QFUQ01CRRMD No results 16327 JY8QFUQ01BHW19 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16328 JY8QFUQ01CWNBW No results 16329 JY8QFUQ01AHGS6 productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame + tctctggtggctccatcagcagtggtaatcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctataaacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 16330 JY8QFUQ01CC0X3 No results 16331 JY8QFUQ01DE0TH unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16332 JY8QFUQ01BN76B productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARILTLFAVVTSSGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 75 of V-REGION: 'C' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); cctctggatttaccttcagtaattatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggcCcgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16333 JY8QFUQ01DQANR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggattttggaccgtactggggccaggaacctgtcaccgtctcctcagctccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16334 JY8QFUQ01BG3Q7 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16335 JY8QFUQ01APOB5 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame + ctctggattcaccgtcagtaccaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16336 JY8QFUQ01ATQIC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - gcctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16337 JY8QFUQ01C5U2S No results 16338 JY8QFUQ01C9HMD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16339 JY8QFUQ01CV1WW productive Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16340 JY8QFUQ01BPSMC No results 16341 JY8QFUQ01A507Y No results 16342 JY8QFUQ01CHLRP No results 16343 JY8QFUQ01C431D unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggtttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca 16344 JY8QFUQ01CHKLB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggctt 16345 JY8QFUQ01A9DAX productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 16346 JY8QFUQ01BLRJO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVPHQNIIYLDYW in-frame - ctctggattcgactttagcagcgcttccatggcctgggtccgccaggctccagggaaggggctggagtggatctcagctgtcagtggacgtggtgacaacaccttctacgcagcctccgtgaagggccggttcaccatctccagagaccattccaagaacacgctgtggcttcaaatgaacaacctgagagccgaagacacggccctatattactgtgcgagggaagtcccacatcaaaatataatctaccttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16347 JY8QFUQ01CDBPL unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16348 JY8QFUQ01DTV3M unproductive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARETLPLGVRG#FDNW out-of-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgggagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttaggggtttttcgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccgatcggtcttcccccatggcgccctgctccaggagcacctccgagagccanagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16349 JY8QFUQ01C9948 productive Homsap IGHV3-7*03 F 864 88.94 193/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctgtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16350 JY8QFUQ01DFBNU unproductive Homsap IGHV3-33*03 F 932 92.2 201/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGGSSGWFGRCGRL# out-of-frame + cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggcagcagtggctggtttggacgttgtggacgtctggggccaagggaccgacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16351 JY8QFUQ01AUK00 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1031 97.25 212/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtaggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 16352 JY8QFUQ01CVO2O productive (see comment) Homsap IGHV3-7*01 F 1021 97.22 210/216 nt 96.76 209/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSGFYSTGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtacctattggatggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16353 JY8QFUQ01CWGAA unproductive Homsap IGHV4-61*02 F 989 95.81 206/215 nt 94.88 204/215 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-21*01 F 3 8 7 X 8.7.X [1.17.38.11] CTNGGHYYGSEFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'GCAGTG' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); tctctggtgactccatcaGCAGTGgcagttactactggagctggattcggcagcccgccgggaagggactggagtggattgggcgtttgcataccagtgggggcCaccgactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtactaatggcgggcattactatggttcggagtttgactactgggggccagggaaccctggtcaccgtctcctcaggcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16354 JY8QFUQ01BJ4VI productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTRSSNSAYDYW in-frame + cctctggattcacgtttagtaacagttggatgggctgggcccgccaggctccagggaaggggctggagtgggtggccagcacaaaccaagatgcaagtgagaaaaagtatgtggactctgtgaggggccgattcaccatctcaagagacaacgccaagaactcactgtatttacaaatgaacagcctaagagccgaggacacggctttatatttctgtacgaggtccagtaacagcgcttatgactattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggcttnttcccccga 16355 JY8QFUQ01BC4JR productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 927 86.89 212/244 nt 86.48 211/244 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); gaccctcaccctgacctgcgacttctctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgGggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16356 JY8QFUQ01DJBV8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame + ctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16357 JY8QFUQ01CF9B0 No results 16358 JY8QFUQ01B590E unknown (see comment) Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16359 JY8QFUQ01DOUJ6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F (see comment) 776 84.58 181/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 6 22 8.6.22 [2.16.38.11] CARVKTDYYDSSGSYLPLYFFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) gtctctggtgactccttcagaactcactactggagttggattcgaancccccgggggagganattggaaggattggcaatatatatatattgggaccaccaactacaaccCcctccctcaagagtcgagtcaccatgttagtggacacgtccaagaagcagttctccctgagactgagttctgtgaccgctgcggacacggccatgtattattgtgcgagggtcaagactgattattatgatagtagtggttcttacctgcccctgtatttctttgattactggggccagggaaccccggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16360 JY8QFUQ01DKP7D productive Homsap IGHV3-9*01 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 8 8 26 8.8.26 [2.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cgtctctggattcacctttgatgattttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 16361 JY8QFUQ01BUQBO productive (see comment) Homsap IGHV1-18*01 F (see comment) 759 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 20 8.8.20 [0.17.38.11] CARDKKDYYDRRGYFGHYFDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 71 of V-REGION: 'TC' (2 nucleotides at position 118 to 119 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'G' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); tggttacaccattagtgactctggcttcagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgctgagaatggtgacagaaatcgtgcaccgaagttTCccaagacagagtcaGccctgacgacagacacgtccacgaatacagcctatatggagatgaggggcctcacacctgacgactcggccatatattactgtgcgagagacaaaaaggattattatgatagaagaggttacttcgggcactactttgacgcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16362 JY8QFUQ01B8SPS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16363 JY8QFUQ01BS3U9 productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 91 to 96 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagttTtctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16364 JY8QFUQ01B8G46 productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16365 JY8QFUQ01A6DKS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 87.5 189/216 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGIVGASMQADWFHPW# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); tctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagGggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaAagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctgggggccagggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16366 JY8QFUQ01CJLYY unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16367 JY8QFUQ01CWGZQ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.16.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattgggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16368 JY8QFUQ01B6BSN unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 129 62.82 49/78 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16369 JY8QFUQ01A8GWB productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [2.17.38.11] CTRGRSDAWELSDHW in-frame - gtcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 16370 JY8QFUQ01ARO6U unproductive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*03 F 558 93.7 119/127 nt 92.91 118/127 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD6-19*01 F 2 8 X X 8.X.X [0.3.31.11] CARGPVSGWYTDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatacaccttcaccgtctactatctattctggggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactgggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16371 JY8QFUQ01CWYZU productive Homsap IGHV3-7*03 F (see comment) 374 82.73 91/110 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 X X 19 X.X.19 [X.X.36.11] CARDRYSSDSSYYMPNWLDPW in-frame + Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgtttgggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16372 JY8QFUQ01BVW0E productive (see comment) Homsap IGHV3-13*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacaCcatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcagccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgcaaccggtgcacggtgtcgtggaactc 16373 JY8QFUQ01CP6A0 productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1007 94.64 212/224 nt 93.75 210/224 nt Homsap IGHJ6*01 F (see comment) 180 76.19 48/63 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtggctctgctatgcactgggtccgccaggtttccgggaaAagggctggagGtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatttggaaatgaacagtttgaagagggaggacacggccgtgtattactgtgtgagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggtcaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16374 JY8QFUQ01BDVTF productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgtcaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggagccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16375 JY8QFUQ01CLS6B No results 16376 JY8QFUQ01BCQEZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16377 JY8QFUQ01BFHKG productive Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16378 JY8QFUQ01ALEHP productive (see comment) Homsap IGHV3-33*03 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16379 JY8QFUQ01A0JCP unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 127 69.64 39/56 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found ctctggattcacctttagtaaccattggatgaactgggtccagggcttcttcccca 16380 JY8QFUQ01BD5YC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 16381 JY8QFUQ01ATPJW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame + ctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 16382 JY8QFUQ01ALDGZ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 800 86.05 185/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'CC' (2 nucleotides at position 111 to 112 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaaCCccctcccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgccctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 16383 JY8QFUQ01B2TGN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 16384 JY8QFUQ01C0K37 No results 16385 JY8QFUQ01CYX7E productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.69 196/221 nt 87.78 194/221 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDRSMAVRATHAFHIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'T' (1 nucleotides at position 145 to 145 in the user submitted sequence), (cause frameshift); tctctggtgactccattggtagcagtgcctactactGggggctgggtccgccagccccccgggaaggggctggagtggattggaagtatctattatggtggcaacacctactacaacccgtccctcaggagtcgagtcagcattTtccgcagacacgtccaagaaccagttctccctgcatctctactccgtgaccgccgcagacacggctctgtattactgtacgaatgaccgttcgatggccgttcgtgcaactcatgcttttcatatctggggcctagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16386 JY8QFUQ01CZ9PX productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16387 JY8QFUQ01CIIGJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 16388 JY8QFUQ01CQCD8 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16389 JY8QFUQ01DF1JA productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CASGSGWTAEYW in-frame + tctctgaattcaccgttagcagtcattggatgaattgggtccgccaggctccagggaaggggctggaatgggtggccaacataaaacaagatgcaagtgagaaaaactatgtggactctgtgaagggccgattcaccatctcccgagacaacgccaagaattcactgtatctgcaaatgaacagcctgagactcgaggacacggctgtgtatttctgtgcgagtggcagtggctggacagctgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16390 JY8QFUQ01B0B79 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 798 88.61 179/202 nt 88.12 178/202 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 8 11 8.8.11 [1.17.33.11] CATEKPGNEFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 15 nucleotides (from position 155 in the user submitted sequence), (do not cause frameshift) gtctggattcaccctcagttcctatgtcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcattggatttaatggacgcagcgagtattatgcagactccgtgaagggccgattcaccatctccagagacaattctctgcaaatgaacaatctgagagtcgaggacacggctgtctattactgtgcgactgagaaacccggcaacgaatttgattactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag 16391 JY8QFUQ01BBN8Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGICYAEPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CCG' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift); cctctggattccagcctcgaCCGacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtatatgctacgccgagcccctcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16392 JY8QFUQ01C1DCR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CAKQTIFDYYYYG#LDVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggttttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16393 JY8QFUQ01BIBVI No results 16394 JY8QFUQ01C5X9S unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 679 94.08 143/152 nt 8 8 X 8.8.X [1.17.16.X] null - No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatg 16395 JY8QFUQ01AMCOH productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDNARSYYSGVPDFW in-frame - gcgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16396 JY8QFUQ01AW6G6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16397 JY8QFUQ01CDGWO No results 16398 JY8QFUQ01CCWMB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16399 JY8QFUQ01DDGIT unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 60 100.0 12/12 nt 2 X X 2.X.X [1.X.X.X] null + No rearrangement found cctctggattca 16400 JY8QFUQ01CK7QF unproductive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 848 87.33 193/221 nt 86.88 192/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] CARAWLDP#YFDSW out-of-frame + stop codons in FR3-IMGT at codon 103 of V-REGION: 'G' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacgtcgccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattaGctgtgcgagggcgtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgctgcctggtccagggcttcttccccca 16401 JY8QFUQ01CC4MM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame + cctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16402 JY8QFUQ01CE2OJ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 781 84.98 181/213 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGEECRSGSCYSVWFDPW in-frame + Low V-REGION identity (84,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtgggtccttaagtgactcctactgggcctggatccgccagcccccagggaagggcctggagtacattggggagatcagtcatgatggtagaaccatgttcaattggtccctcaagagtcgactcaccatctcagtagacacgtccaagaatcaattctccctgagattgacctctgtgaccgccgcggacacggctgtttattactgcgcgagaggcgaggaatgtcggagtggaagttgctactccgtttggttcgacccctggggccagggagcccaagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16403 JY8QFUQ01BQ997 No results 16404 JY8QFUQ01CRDLW productive Homsap IGHV3-11*01 F (see comment) 789 84.55 186/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARYRGSYYDYGGVDVW in-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release aacctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16405 JY8QFUQ01A829Y unproductive Homsap IGHV3-64*02 F 953 93.95 202/215 nt Homsap IGHJ6*01 F (see comment) 88 61.02 36/59 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [0.17.38.11] CVTCGDYSYEY# out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16406 JY8QFUQ01CFDZM productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame - ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16407 JY8QFUQ01BKQXZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcagccatcccatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16408 JY8QFUQ01C9GN1 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16409 JY8QFUQ01DJZVC productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16410 JY8QFUQ01COCK0 No results 16411 JY8QFUQ01A9JXU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16412 JY8QFUQ01AQ5FG No results 16413 JY8QFUQ01CTBD0 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 164 to 164 in the user submitted sequence), (cause frameshift); aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16414 JY8QFUQ01ANWRU productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag 16415 JY8QFUQ01BFXW7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - tctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16416 JY8QFUQ01C8BJI No results 16417 JY8QFUQ01BXPO3 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctcctggattcaCcctttggttattatggcatgactggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16418 JY8QFUQ01CI27V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKLENSSGNEDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttaacgactatggcatgacttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactggtagtggtgataatgcctactacgcagacttcgtgaagggccgattcgccatctccagagacaattccaagaacatgttgtatttgcaaatgaacaacctgcgaggcgaggacacggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16419 JY8QFUQ01DFM1O productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 74 to 75 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggctgggagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16420 JY8QFUQ01CFTLV productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDWGGKYAPLDNW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacatcttcaccggctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccatcagtacagcctacatggaactgaacaggctgatgtctgacgacacggccatgttttactgtgcgagagattggggtgggaagtacgcaccgctagacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16421 JY8QFUQ01A2GTY No results 16422 JY8QFUQ01BW0NV No results 16423 JY8QFUQ01CUBGH productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16424 JY8QFUQ01AYGYZ No results 16425 JY8QFUQ01C0YRF No results 16426 JY8QFUQ01AO3TE No results 16427 JY8QFUQ01AARXS productive (see comment) Homsap IGHV3-33*03 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); cgtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16428 JY8QFUQ01A2R0M productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + cctctggatttaccttcagtaatgattggatgatctgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16429 JY8QFUQ01BPZUU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgcctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16430 JY8QFUQ01BGNWL productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 389 90.53 86/95 nt 89.47 85/95 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 22 to 26 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctgggcaccctcctccaaaagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16431 JY8QFUQ01CSQMJ productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16432 JY8QFUQ01CDRSX productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16433 JY8QFUQ01DRD56 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16434 JY8QFUQ01DGSIU unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 874 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [2.16.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) agtctctggattcaccttcagtagttatagtatgatctggGgtccgccaggctccagggaaggggctggagtgggtcgctcaattagtcataccgggggttccaaatattacggagactcactgaagggccgattcgccatctcaagagacaacgacaagaactcactgtatctgcaaatgaccagcctgagagccgaggacacggctgtctactactgtgcgagagccctaatagtagtgggctggtgccccctgtctattgggcagggaaaccctgggtcaccgtctccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16435 JY8QFUQ01C3U9E No results 16436 JY8QFUQ01B6HCR productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctgccagcctccaccaacgggcccatcggctcttccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16437 JY8QFUQ01C5SYP productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16438 JY8QFUQ01C1DJZ unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 71 93.75 15/16 nt 4 X X 4.X.X [1.X.X.X] null + No rearrangement found tctggattcagtttca 16439 JY8QFUQ01B3P4D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16440 JY8QFUQ01BUXDW No results 16441 JY8QFUQ01CZQ30 No results 16442 JY8QFUQ01A9DAA productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); cctcgggactcatatttagcagctataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagagcCtgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16443 JY8QFUQ01A2Y6Z productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 7 8 16 7.8.16 [2.17.38.11] CAFSRALTGKWIDYLDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) gcctctggattcatctcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16444 JY8QFUQ01CZ4QD productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 811 85.84 188/219 nt 84.93 186/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) ccctctgggattcaccttCagtacatgactggatgcactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16445 JY8QFUQ01B9LGG unknown (see comment) Homsap IGHV3-72*01 F 105 53.49 69/129 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons tctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 16446 JY8QFUQ01AA3KH unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgtccatagcatgaactggGgtccgccaggctccagggaaGggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaGggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16447 JY8QFUQ01BAKZQ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 674 79.53 171/215 nt 78.6 169/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'GGCT' (4 nucleotides at position 129 to 132 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccCgtgagggggcgGGCTtatcgaagtctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16448 JY8QFUQ01ACUYK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtggttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16449 JY8QFUQ01DIM4C unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDYGDCRGGRCYAEPLDY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGcctcgccgacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16450 JY8QFUQ01B811Q No results 16451 JY8QFUQ01B94XC unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW# out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tctctggtggctCccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccCctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaaggggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16452 JY8QFUQ01C2X6I unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 425 76.35 113/148 nt 8 7 X 8.7.X [1.17.16.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01C2X6I ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag 16453 JY8QFUQ01CPA03 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDISSGQHLPLGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagaagttataatatgaactgggtccgccaggctccagGggaaggggctggagtgggtcgcgtccattagtcctagtagtaatttcatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgagagatattagtagtggtcaacacctaccgttgggctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16454 JY8QFUQ01AHSTQ No results 16455 JY8QFUQ01BQ877 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccCagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcaggcctccaccaagggcccatcggtcttccccctggcgccctgctcccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16456 JY8QFUQ01C4QOQ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + ctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtcaccgtctcctcaccatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16457 JY8QFUQ01AFE1S productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaagggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16458 JY8QFUQ01BBPWV productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16459 JY8QFUQ01AQKK1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD6-19*01 F 3 8 8 14 8.8.14 [1.17.38.11] CVKGGQWLVSNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtgctactggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacactctgtatcttcaaatgagcagtctgagagctgaggacacggctgtgtattactgtgtgaaaggggggcagtggctggtatccaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa 16460 JY8QFUQ01C7RYA productive (see comment) Homsap IGHV3-30*01 F 951 92.73 204/220 nt 91.82 202/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [2.17.38.11] CPKTGPGHSSPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); agcctctggattcaccttccgaagttatgatctgcactgggtccgccaggctccaggcaaGggggctagagtgggtggcatttaGtttcaaacgatggaagtgacacagactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaagacgctatatctgcaaatgaacagcctgagagttgaggacacggctgtgtattactgtccgaaaaccggccccggtcatagcagcccctttgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16461 JY8QFUQ01AZQ1P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDYGNCAGGRCYSIPLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 64 of V-REGION: 'TTT' (3 nucleotides at position 99 to 101 in the user submitted sequence), (do not cause frameshift); cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccgggaagggggctggagtgggtctcaggcatcactgatggtggtgggTTTttgacatactacgcagacgccgtgcagggccggtttattatttccagagacgattcccagaacacgatagatctgcaaatgaacaatttgagagccgacgacacggccatctattactgtgtgaaagattacggcaattgtgctggtggtcgctgctactcgattccccttgactattggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacaacaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16462 JY8QFUQ01A3IMT No results 16463 JY8QFUQ01DLAXE productive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*03 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARERSASMGAARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 99 to 101 in the user submitted sequence), (do not cause frameshift); tctctggtggccccatcggcagtggtgcctactactggacctggatccggcagcccgccgggaagggattggagtggctcgggcgtgtttatagtggtGGGgggatcatcaattacagtccctccctcaagagtcgaatcaccatgtcgatagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttatattactgtgcgagagaacgtagtgcctcgatgggcgctgcgagagaacttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16464 JY8QFUQ01APECD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1081 99.54 218/219 nt 98.63 216/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); gcctctggattcaccGttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16465 JY8QFUQ01DB2YL productive Homsap IGHV4-61*02 F 848 86.88 192/221 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [1.17.38.11] CARGMATIKTVRFDPW in-frame + tctctggtggctccatgaggagtggaattaattcctggacatggatccggcagcccgccgggaagggactggagtggattgggcgtatctatatcaatggagacaccaactacaatccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaaacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtggacggtgtcgtggaactcag 16466 JY8QFUQ01CSVHN productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 830 86.43 191/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARAGGWTPYFDSW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaattactactggaactggatccgccaatccccagggaagggactggagtggattggatatatctactatgctggggccaccaacCtcgcccccctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16467 JY8QFUQ01BAXD9 productive Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16468 JY8QFUQ01DQ5GU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16469 JY8QFUQ01B5TMW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16470 JY8QFUQ01A98XI productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16471 JY8QFUQ01BNJBB productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctctgggggActccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccccctaagatgggaaccgtggtcgtcgcatgcctggctccagggcttcttcccccag 16472 JY8QFUQ01AEHFZ productive (see comment) Homsap IGHV3-72*01 F 858 87.44 195/223 nt 87.0 194/223 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD4-11*01 ORF 1 8 10 13 8.10.13 [1.17.38.11] CVRGLQSNYYGMDVR in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaAaatttaacagttacagtacagaatatgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaatttactgtatctgcaaatgaacagcctgagaagcgaggacacggccgtatattactgtgttagaggcctacagagtaattactacggtatggacgtcaggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16473 JY8QFUQ01B76BC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16474 JY8QFUQ01DDSJ6 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPGWDKWKC#NWFDPW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatcccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16475 JY8QFUQ01DKM8F productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcCacttttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16476 JY8QFUQ01DPWM1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcaccagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16477 JY8QFUQ01BOMV5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 16478 JY8QFUQ01CD2Z7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 824 86.7 189/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame - tctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16479 JY8QFUQ01CFS2I No results 16480 JY8QFUQ01CQGX0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame - cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16481 JY8QFUQ01AGVKW productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16482 JY8QFUQ01BCFIK productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 16483 JY8QFUQ01CS0TG productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag 16484 JY8QFUQ01AR2CD No results 16485 JY8QFUQ01CZKFT productive Homsap IGHV4-4*07 F (see comment) 542 73.11 155/212 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 2 8 7 14 8.7.14 [0.17.38.11] CARVRDAYTAGHFDSW in-frame - Low V-REGION identity (73,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggtgactctgtcactatgtcttattgggcctggatacgtcagcccgccgggggaggcctggagttaattggacgaacttctgccagtccaaaagttacctacaatccctccctcaggagtcgagccaccatattcgaagacacttcaaagaatcaacttatcttgaaattggcctctgtgaccgccgcggacacggccatctactactgtgcgagggtccgtgatgcctacaccgctggacactttgactcctggggcccgggaaccctggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccctca 16486 JY8QFUQ01AA617 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 289 65.16 101/155 nt 8 8 X 8.8.X [1.17.17.X] null + No rearrangement found Low V-REGION identity (65,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16487 JY8QFUQ01BREFM productive Homsap IGHV3-9*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - ctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16488 JY8QFUQ01AS22B productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtggaactcag 16489 JY8QFUQ01BO010 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CAKGGPCGGDCHTLLFDHW in-frame + gtctggattcgcatttagcagctatgccatgaactgggtccgtcagggtccagagaaggggctggagtgggtctcaggtattagtggtactgggggtagcacatacaacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacagcctgagaggcgaggacacggccgtatattactgtgcgaaaggaggcccttgtggtggtgactgccataccctgttgtttgaccactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa 16490 JY8QFUQ01CVQ02 unknown (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtggcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 16491 JY8QFUQ01B3KMM No results 16492 JY8QFUQ01CE130 productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttccccca 16493 JY8QFUQ01CIEX4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag 16494 JY8QFUQ01CVV6S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 698 80.28 175/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16495 JY8QFUQ01BU0E2 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 16496 JY8QFUQ01CTD2R productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 16497 JY8QFUQ01BR8J5 No results 16498 JY8QFUQ01AJ4OL No results 16499 JY8QFUQ01CN7J6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16500 JY8QFUQ01DSJO1 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 84.62 187/221 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD4-17*01 F 1 10 7 X 10.7.X [1.17.38.11] CARRWARQRLVMDYFDYW# out-of-frame - in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattgGgggctggatccggcagGcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggggccaggggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16501 JY8QFUQ01DBY4W unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 353 86.17 81/94 nt 8 5 X 8.5.X [1.17.X.X] null - No rearrangement found ctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 16502 JY8QFUQ01CG389 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-9*01 F 2 8 8 21 8.8.21 [2.17.38.11] CVREGIEYYEISTGQYYYDMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcacAttttagcggctatggcatgagctgggtccgccaggctgcagggaaggggctggaatgggtctcatttattagtggtaagagcggcaacatatactatgcagaccccgtgaagggccggttcaccatctccagagacaactccaagaataggctcttcctgcagatgaacagcctgagagtcgaggacacggccaaatattactgtgtgagagagggcatagagtattacgaaatctcgactggacagtactactacgatatggacgtctggggccaggggaccacggtcaccgtcctctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16503 JY8QFUQ01C5I4I productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtGgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttgccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16504 JY8QFUQ01CK78N productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctgggattcaccttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16505 JY8QFUQ01BYDI5 productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 16506 JY8QFUQ01DEEHD productive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcacctttcatgattataccatgcactGgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactcaggc 16507 JY8QFUQ01B14O3 unproductive (see comment) Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKGHGRGSGTLVT#FDHW out-of-frame + stop codons Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaaggacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16508 JY8QFUQ01BQVL9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16509 JY8QFUQ01CF6RJ productive (see comment) Homsap IGHV1-2*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 1 8 8 22 8.8.22 [0.17.38.11] CARGGPERFSTSSVWYDPSLFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); tggatacaccttcGaccgacaactatatgcattgggtgcgacaggtccctggacaagggcctgagtacatgggattcattaaccctaacagtggtggcacaaactctgcacagaagtttcagggcagggtcaccatgaccagggacacgtccgtcagcacagcctacctggaactgaacagactgagacctgacgacacggccgtatattactgtgcgagaggagggcccgaacgcttctcaacaagcagcgtctggtacgacccgagcctttttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16510 JY8QFUQ01DNZPN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16511 JY8QFUQ01C6JRR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 915 92.89 196/211 nt 92.42 195/211 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [X.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) tggatcaccgtcagtacctatagcctgaactgggtccgccaggctccaggaagggctggagtggatctcatccattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctgggcccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16512 JY8QFUQ01AZPSW productive (see comment) Homsap IGHV3-9*01 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [2.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gcctctggattcacttttgatgGactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactactttcccgaaccggtgacggtgtcgtggaactcag 16513 JY8QFUQ01BG637 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16514 JY8QFUQ01C2CFT No results 16515 JY8QFUQ01BV968 unproductive (see comment) Homsap IGHV3-74*03 F (see comment) 311 73.95 88/119 nt 73.11 87/119 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 X 1 X X.1.X [X.X.38.11] CVRGTRGMER##DYW out-of-frame - stop codons Low V-REGION identity (73,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); agcctctggattcattttcagtaactactggattcaccatctCcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaaggggaatggagcgggattgactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16516 JY8QFUQ01C8VRV unproductive Homsap IGHV3-7*02 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ2*01 F 76 60.38 32/53 nt Homsap IGHD5-12*01 F 2 7 8 X 7.8.X [1.17.38.11] CARDQVTEDY## out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtctgccaggctccagggaaagggctggagtgggtggcccacataaAaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16517 JY8QFUQ01CODF3 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 709 85.13 166/195 nt 84.62 165/195 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) tgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16518 JY8QFUQ01C5139 unproductive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARVRARSNSHPGHSWFD#PW out-of-frame + tctctggtggctccatcagcagcagtagttactactcgacctggctccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagtcaccccggccacagctggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16519 JY8QFUQ01AZQM7 No results 16520 JY8QFUQ01CNHLY No results 16521 JY8QFUQ01CRE6I productive Homsap IGHV2-5*02 F 1129 96.3 234/243 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [9.17.38.11] CAHRSFYGDYVFDPW in-frame + accctcacgctgacctgcaacttctctgggttctcactcaccactaggggaatgggtgtgggatggatccgccagcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgatacaggccatctctgacgagcaggctcaccatcaccaaggacacctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacagatcgttctacggcgactacgtcttcgacccctggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 16522 JY8QFUQ01AWGVW productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16523 JY8QFUQ01CTE4U No results 16524 JY8QFUQ01B81W4 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 16525 JY8QFUQ01A8NED productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcactctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgt 16526 JY8QFUQ01B5KCJ productive Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARYRGSYYDYGGVDVW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16527 JY8QFUQ01ACVST No results 16528 JY8QFUQ01DICNL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16529 JY8QFUQ01DL1VC No results 16530 JY8QFUQ01A8YGX unknown (see comment) Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 84 51.52 68/132 nt 8 10 X 8.10.X [2.17.9.X] null - No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16531 JY8QFUQ01DN458 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 791 85.58 184/215 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [0.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16532 JY8QFUQ01DLL3K unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSSR## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccagggaaggggctggagtgggtctcaactattcgtgcccgtggtgataggacacactacgcggactccgtgAaagggccgcttcaccatctctagagacaattcaaaggacaccctgtatttgcaaatgtacagcctgcgagtcgaggacacggccgtctattactgtgcgaacgaagtcgggtactgtagtagtcggggggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16533 JY8QFUQ01A1DJR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16534 JY8QFUQ01AC413 No results 16535 JY8QFUQ01A82JG productive (see comment) Homsap IGHV3-11*01 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 24 8.8.24 [1.17.38.11] CARDCHVDILTGYYRGSPPSCGLGVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'T' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); tctggattcaagctcggtgactactatatgaattggatccgccaggctccagggaaggggctggagtgggtttcatatattagtcttggtggtagccccacatattTatgcagactctgtgaagggccgattcaccatctccagggacaacgccaacaattcactatatctacagatgagtgccctgagagccgaggacacggccgtatattattgtgcgagagattgtcatgtcgatattttgaccggttattatcggggttcgcctccttcttgcggtctgggcgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16536 JY8QFUQ01BYW9M unproductive (see comment) Homsap IGHV3-9*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKNVGV*MTVDGTGPI*LL# out-of-frame + stop codons ctctggattcacctttaataattatggcatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaggtattagttggaatagcggaagtagagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcagatgaacagtctgagagctgaggacacggctttgtattattgtgcaaaaaatgtcggggtataaatgacagtggatggtacgggccctatttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16537 JY8QFUQ01CWBOS productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 16538 JY8QFUQ01CKIZZ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt 84.62 187/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 10 7 X 10.7.X [1.17.38.11] CARRWARQRLAE#YFDYW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattggggctggatccggcagcCccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtctctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggctgagctactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 16539 JY8QFUQ01AWUTM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16540 JY8QFUQ01BFX0R unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 117 54.07 73/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons gctctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16541 JY8QFUQ01C8PQW productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaaaaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcgaccgtctcctcagcatccccgaccagccccaagtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16542 JY8QFUQ01C4776 No results 16543 JY8QFUQ01BSZM3 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1007 94.64 212/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactc 16544 JY8QFUQ01A8PFM productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame - Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacaccttcaccgactacttcatacactggctgcgactggcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaattatgcacggaactttcagggccgggtcaccatgacccgcgacacgtccgtcagaacagtatatgtggaggtgaacagcctgaaatctgacgacacagccatttattactgtgcgcgaggcttttatggtgaccactttgactcctggggccagggagccgtggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16545 JY8QFUQ01AG2V6 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*01 F or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 147 56.82 75/132 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found ctctggattcaactttggcatctataccatggcctgggtccgccaggctcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16546 JY8QFUQ01COULV productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16547 JY8QFUQ01DCGYU unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANYW# out-of-frame + gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16548 JY8QFUQ01AUNOE unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-17*01 F 3 9 7 X 9.7.X [2.16.38.11] CARGEMTAEYYLDY## out-of-frame - in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtgttaactggtggagttgggtcgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactaccttgattactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16549 JY8QFUQ01DF5I6 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcgatattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16550 JY8QFUQ01C7L3B unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [2.17.38.11] CATGGHSGG#YW out-of-frame - in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); gtctcgggtgactccatcactcctaactcctggagctggatccggcagAcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaAgttttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgacggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16551 JY8QFUQ01CPAX9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16552 JY8QFUQ01DC09Y unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 16553 JY8QFUQ01CJM85 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - tgtctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16554 JY8QFUQ01BSJ7Y productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame + gcctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctccatcagcatccccgaccacgccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16555 JY8QFUQ01C03JM productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 939 93.46 200/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-3*02 F 3 8 8 12 8.8.12 [0.17.38.11] CARGFSTYYGMDVW in-frame + cggatacaccttcacctattattttatacactgggtacgacaggcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtagcacaacctatgcacagaagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggacctgagcagcctgaaatctgaggacacggccgtttattattgtgcgagaggctttagcacctactacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16556 JY8QFUQ01AFMKM productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 11 8.7.11 [2.17.38.11] CARGGRGLRMTTG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); cagtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagagggggacgggggttaaggatgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16557 JY8QFUQ01AITKC No results 16558 JY8QFUQ01A865A unproductive (see comment) Homsap IGHV3-7*01 F 987 94.55 208/220 nt 94.09 207/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); gacctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 16559 JY8QFUQ01ATZ1Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16560 JY8QFUQ01BJXU7 productive Homsap IGHV3-7*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16561 JY8QFUQ01BBLZF productive (see comment) Homsap IGHV3-48*01 F 1076 99.54 217/218 nt 98.62 215/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.16.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctaagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16562 JY8QFUQ01B8PFI unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16563 JY8QFUQ01DO20Y productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 715 96.73 148/153 nt 96.08 147/153 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 X 10 8.X.10 [2.14.27.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 53 of V-REGION: 66 nucleotides (from position 73 in the user submitted sequence), (do not cause frameshift) ccctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtggatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16564 JY8QFUQ01DQNCL unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGAPWRWCLLHLLF#DLW out-of-frame + in FR3-IMGT at codon 66 of V-REGION: 'T' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); cctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcatTtttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggctccgtggcgttggtgcttactacatctactattttcgacttatggggccagggaaccctggtcactgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16565 JY8QFUQ01BZ7BR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16566 JY8QFUQ01BE1D5 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 96 of V-REGION: 'T' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagTccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16567 JY8QFUQ01BN1RG productive Homsap IGHV1-8*01 F 831 87.85 188/214 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD3-16*02 F 3 8 8 15 8.8.15 [0.17.38.11] CARGRGTVWVQEGLDVW in-frame + tggatacaccttcacctcttatgatatccactgggtgcggcaggccactggacaagggctggagtggatgggccggatgagccccaatagcggtaacacaggctttgcacagaagttccacggcagagtcaccgtgaccaggaatctctccataaatacagcctacttggagctgggtagcctgaggtctgacgacacggccatttattactgtgcaaggggaaggggaactgtctgggtccaagagggtcttgatgtctggggccaagggacagtggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16568 JY8QFUQ01CF75G productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaanatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16569 JY8QFUQ01A0RX1 No results 16570 JY8QFUQ01DPEMX productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 71 of V-REGION: 'T' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgtTaaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16571 JY8QFUQ01C0ZI3 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 947 94.34 200/212 nt 93.4 198/212 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [0.16.37.11] CARDGGHSYGPSFDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 122 in the user submitted sequence), (cause frameshift) tggatacaccttcaccaggtacattatgcactgggtgcgacaggccctggacaagggcttgagtggatgggaataatcaaccctagaggtgttagcagaagctacgcacagaagttccaggcagagtcaccatgaccaccgacacgtccacgagcacagtctatatggagctaaacagcctgagatctgaggacacggccgtttattactgtgcgagagatggagggcacagctatggaccctcctttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16572 JY8QFUQ01B0G9Q productive Homsap IGHV3-48*03 F 824 86.7 189/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - ctctgggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16573 JY8QFUQ01CAIKC productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD1-1*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAREPGRGYTPAMNWYFDLW in-frame + ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcagatgaacagcccgagagctgaggacacggctgtgtattactgtgcgagagagcctgggaggggttatacacctgcaatgaactggtacttcgatctctggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggccttcttcccccag 16574 JY8QFUQ01C0HVG unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacacagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctctcagcctccaccaagggcccatcggtcttcccctggcaccctctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16575 JY8QFUQ01CF81C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16576 JY8QFUQ01CYFDW productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame - tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16577 JY8QFUQ01BPCSK productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKRLQAVADDAFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); cagcctctggactcaacattggcaactatgacatgacctgggtccgccaggGctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16578 JY8QFUQ01B8407 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 987 94.55 208/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + ctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16579 JY8QFUQ01AODXR No results 16580 JY8QFUQ01DA3J2 No results 16581 JY8QFUQ01DCLJL unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt 87.27 192/220 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [2.17.38.11] CAEK*GGRRWL#WYFDFW out-of-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'ACT' (3 nucleotides at position 86 to 88 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 149 to 149 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'AT' (2 nucleotides at position 216 to 217 in the user submitted sequence), (cause frameshift); agcctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattACTaatggtggtggtggtgtcgtactctacgcagactccgtgAaagggccgattcaccatctcCcagagacaatGcccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgATttagtttctgtgcggaaaaataggggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16582 JY8QFUQ01ALIAX unproductive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 X 10.7.X [1.17.38.11] CARDRGP*QLVQNGI#DYW out-of-frame - stop codons tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcgggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16583 JY8QFUQ01B96JM unproductive Homsap IGHV3-72*01 F 971 92.86 208/224 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16584 JY8QFUQ01CLIW9 unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 90 58.33 42/72 nt 56.94 41/72 nt X X X X.X.X [24.X.X.X] null - No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 3 nucleotides (from position 90 in the user submitted sequence), (do not cause frameshift) agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgctctcggaggtgctcctggagcagggcgccagggggaagaccgatgggcccttggtggaggtgacgaagccaccagag 16585 JY8QFUQ01B1HSY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 809 86.51 186/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [1.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) cgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16586 JY8QFUQ01DIDT7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaggGgaaggggctggGtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16587 JY8QFUQ01BTP79 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 105 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16588 JY8QFUQ01C7RDR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctccggattcagtttcagtacttataacatgaaTttgggtccgccaggctccagggaaggGggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16589 JY8QFUQ01CBQ9G productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 742 82.87 179/216 nt 82.41 178/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 2 8 8 18 8.8.18 [1.16.38.11] CATDLVTSTPGVLDDAYAFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctctggaatcacgttcaacagacatggcattcactgggtccgccaggccctggcaggggcctggagtgggtggctgttatgtcccgagacggaagtagacaatactatagagactccgtgaagggccgtttcgccatctccagggacacttccacgaacactgtgtatctgcaaatgaacagtctgagagttgacgactcggctctatatcgctgtgcgacagacttggtgacctccacaccgggagtcctcgatgatgcttatgccttttggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16590 JY8QFUQ01COBZI No results 16591 JY8QFUQ01C6Z8M productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16592 JY8QFUQ01BFQT1 unknown (see comment) Homsap IGHV3-7*02 F 114 59.52 50/84 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16593 JY8QFUQ01A55U4 No results 16594 JY8QFUQ01DMG72 No results 16595 JY8QFUQ01A53U7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - stop codons gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggctagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16596 JY8QFUQ01BHNR2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame + cctctggattcatgtttagtagctttcccatggcctgggtccgccaagctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16597 JY8QFUQ01BTGIG No results 16598 JY8QFUQ01A3GTG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 674 79.53 171/215 nt 78.6 169/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'T' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaAaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactcccgtgaggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagcTcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 16599 JY8QFUQ01C4W5U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 16600 JY8QFUQ01AJMNA productive (see comment) Homsap IGHV2-5*02 F 1111 95.47 232/243 nt 95.06 231/243 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); gacctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcaCttttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16601 JY8QFUQ01CVI6U No results 16602 JY8QFUQ01APZBK No results 16603 JY8QFUQ01CU606 No results 16604 JY8QFUQ01C11P1 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CATLRGGY#FDYW out-of-frame + in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'T' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcCccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaaCcccctccctcaagagtcgagtcTcccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggctactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggcccttgggctgccctggtcaaggactacttcccccgaacccggctgacggtgtcgtggaactcag 16605 JY8QFUQ01C6MTP productive Homsap IGHV3-9*01 F 850 88.43 191/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame - tctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16606 JY8QFUQ01B5NY0 productive (see comment) Homsap IGHV2-5*02 F 1170 97.95 239/244 nt 97.54 238/244 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.17.38.11] CAHRRIRFGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattGgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaact 16607 JY8QFUQ01CJYLC unproductive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKDMVAGQGLLSR#LDHW out-of-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttggaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 16608 JY8QFUQ01CSXUP No results 16609 JY8QFUQ01A3ZD4 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 854 90.78 187/206 nt 90.29 186/206 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 9 nucleotides (from position 15 in the user submitted sequence), (do not cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16610 JY8QFUQ01COXC5 unknown (see comment) Homsap IGHV4-61*02 F 889 89.19 198/222 nt 88.74 197/222 nt 10 7 X 10.7.X [2.17.38.X] null + No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgGggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 16611 JY8QFUQ01A2U2O No results 16612 JY8QFUQ01AVXM4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccgaaggtcttcccgctgagcctctgcagcacccacgccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16613 JY8QFUQ01ADRBF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.16.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaagggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16614 JY8QFUQ01BB1CN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*03 F or Homsap IGHV3-48*04 F 820 86.3 189/219 nt 84.93 186/219 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSGSSDYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); cctgctggattcagttttagttcttatGggcatgaactgggtccgccaggctccagggggggggctggagtgggtctcattcattaacagtgttagtagTtacaaaatactatgtggacccagtgaGggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 16615 JY8QFUQ01CIHG4 productive (see comment) Homsap IGHV4-34*13 F (see comment) 601 76.06 162/213 nt 75.12 160/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [2.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'AGG' (3 nucleotides at position 56 to 58 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'TGG' (3 nucleotides at position 80 to 82 in the user submitted sequence), (do not cause frameshift); gtctctgatggggtcgttcatgggttacctctggaattggatccgccagtcccccAGGggaagggggctggagtggattTGGgggaaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16616 JY8QFUQ01CA2FF unknown (see comment) Homsap IGHV3-74*03 F 118 54.69 70/128 nt 8 8 X 8.8.X [1.17.8.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16617 JY8QFUQ01B2HM0 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 175 75.81 47/62 nt Homsap IGHD3-16*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARAVGQRGYDGTDLW in-frame + ctctggattcatgttcagcagttattggatgagctgggtccgccaggatccagggaaggggctggagtgggtggccaatataaacgaagaaggaagtgagaaatattatgtggactctgggaagggccgattcaggatctccagagacaacgccaagaattccgtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgagagcagtggggcagcgaggctacgacggtacagacctctggggccaagggaccacggtcatcgtctccacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16618 JY8QFUQ01DQDYT No results 16619 JY8QFUQ01AZA5L productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16620 JY8QFUQ01B8XA7 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTDPRYFWGSGFDYW in-frame + ctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16621 JY8QFUQ01C7YSJ productive (see comment) Homsap IGHV3-30*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtCgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 16622 JY8QFUQ01BZVSG No results 16623 JY8QFUQ01DBF0P productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16624 JY8QFUQ01C6C3L productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatcccctgaccagcccccaaggtcttccccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16625 JY8QFUQ01BFX42 unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16626 JY8QFUQ01CO4G6 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16627 JY8QFUQ01BJL9W No results 16628 JY8QFUQ01A2Y3S productive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16629 JY8QFUQ01CK0SW productive Homsap IGHV3-23*03 F (see comment) 894 91.12 195/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CK0SW ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttggttattatggcatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16630 JY8QFUQ01BYYSR productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16631 JY8QFUQ01AARBP productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD2-15*01 F 1 8 10 8 8.10.8 [1.17.38.11] CLRPPRYDPW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 16632 JY8QFUQ01ATVC1 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctgaaatcaccttcagcgaccactacatgagctggatccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16633 JY8QFUQ01CMZOB unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 87 90.48 19/21 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found ctctggattaaccctcagtga 16634 JY8QFUQ01AG2QF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16635 JY8QFUQ01CJVE1 unproductive (see comment) Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgagaacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 16636 JY8QFUQ01CUPVA unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 X 8.8.X [1.17.38.11] CTTTLVWFGGV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcgggggagttaggccaggaaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16637 JY8QFUQ01DH10O productive Homsap IGHV3-9*01 F 887 89.45 195/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CTRSRVSIDLQPSYGMDVW in-frame + cctctggattcatctttgatgattttgccatgcactgggtccggcatgctccagggaggggcctggagtgggtctcaagtatcaactggaatggtgacgtcaaagcctatgcggactccgtgaagggccgattcaccgtctccagagacaacgccaagaactccctgtatctgcaaataaacgatctgagagcagaggacacggccttgttttactgcacaagaagtcgtgttagtatcgacttacagccctcctacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16638 JY8QFUQ01C142N productive (see comment) Homsap IGHV3-72*01 F 921 90.58 202/223 nt 90.13 201/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-8*02 F 2 8 10 17 8.10.17 [1.17.38.11] CTRDTTDTGGQSFNGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggtttccCccttcagtgaccacttcatggactgggtccgccaggctccagggaagggcctggagtgggttggtcgtatcagaaagaaaaccaccggttacaccacagaatatgccgcgtctgttaaaggcagattcatcatttcaagagatgattcagagaactcactgcatctgcaaatgaatggcctgaaaatcgaggacacggccgtgtattactgtactagagatacgacagatacgggtggtcaatccttcaacggtttggacgtctggggccaggggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 16639 JY8QFUQ01A1XO3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcGaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16640 JY8QFUQ01AEAEP productive Homsap IGHV3-74*03 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + tctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16641 JY8QFUQ01B58UQ productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16642 JY8QFUQ01DWOFO productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [2.16.38.11] CAKSPSQVGYYLDCW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 81 of V-REGION: 'A' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagatactggatgcactgggtccgccagctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagAaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16643 JY8QFUQ01CA5S5 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 795 85.98 184/214 nt 85.05 182/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.16.38.11] CARDSSNWSDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'TG' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) tctctggtTGggctccatgagtagtcactattggagttggatccggcaatcttcagggaaggactggagtggcttgactacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16644 JY8QFUQ01C8A3A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16645 JY8QFUQ01B1158 productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame - tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16646 JY8QFUQ01CNI53 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 463 68.06 147/216 nt 67.59 146/216 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (68,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16647 JY8QFUQ01B859W No results 16648 JY8QFUQ01CXANC unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 926 90.62 203/224 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD6-6*01 F 2 8 10 X 8.10.X [1.17.38.11] CTSNSWLDR# out-of-frame - cctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctgggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16649 JY8QFUQ01BLY5C No results 16650 JY8QFUQ01DF5WA No results 16651 JY8QFUQ01A1PLD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactGgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16652 JY8QFUQ01B1OFN productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame - cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16653 JY8QFUQ01AG672 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame - ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16654 JY8QFUQ01A72DW productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame + ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggccaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacgtgtcgtggaactca 16655 JY8QFUQ01BL2OD unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 16656 JY8QFUQ01CO3JF unproductive Homsap IGHV3-72*01 F 1093 98.67 222/225 nt 98.22 221/225 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [2.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcCaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16657 JY8QFUQ01B61QL unproductive Homsap IGHV3-13*01 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 7 X 8.7.X [1.17.38.11] CAGAEAGL#DYW out-of-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggcccctggggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16658 JY8QFUQ01AYPPE No results 16659 JY8QFUQ01DQZLQ productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaacctcagg 16660 JY8QFUQ01CU9MI productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 18 8.8.18 [1.17.38.11] CSTGPSDLSRDYGDYGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'CATGATGGAATG' (12 nucleotides at position 86 to 97 in the user submitted sequence), (do not cause frameshift); atctggattcaccttcagaaactatgccatgcattgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatggCATGATGGAATGtttgatggaagaaatgaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaatacggtgtatctgcaaatggacagcctgagagccgaggacacggctttgtattactgttcgacaggaccctcagaccttagtcgtgattacggtgactacggatttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16661 JY8QFUQ01BTPRA unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 734 91.86 158/172 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctg 16662 JY8QFUQ01BZ30I productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 967 92.44 208/225 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16663 JY8QFUQ01CHZOM productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 833 87.16 190/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); cgtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcAaaggggctggagtgggtgaAcagttatatggtcggatggaactCaaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16664 JY8QFUQ01BJOFQ No results 16665 JY8QFUQ01COKQ0 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16666 JY8QFUQ01DI98R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKGIVGASMQADWFHPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'AG' (2 nucleotides at position 127 to 128 in the user submitted sequence), (cause frameshift); agcctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaaAGgggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16667 JY8QFUQ01BKX5D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16668 JY8QFUQ01CNCWQ unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLFI#NFDYW out-of-frame + stop codons ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttataacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16669 JY8QFUQ01B2RDP No results 16670 JY8QFUQ01CUGFD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame + tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccggaccagccccaagggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtngtcgcatgcctcgtcccagggcttcttcccccag 16671 JY8QFUQ01CZ7WD No results 16672 JY8QFUQ01BI363 No results 16673 JY8QFUQ01CHHZW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16674 JY8QFUQ01BEQQ4 productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16675 JY8QFUQ01DDY03 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16676 JY8QFUQ01BHOMI unproductive Homsap IGHV3-11*01 F 936 92.63 201/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CTRDDRSVRGVTSDY## out-of-frame + ctctggattcaccttcagtgaccacttcatgagttggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtggtagtataatatattacgcagactctgtgaggggccgattcaccatctccagggacaacgccaagaattccctctatctgcaaatggacagcctgagagacgaggacacggccgtgtatttttgtacgagagatgatcgctcggttcggggagtcacctcagactactgggggccagggaaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16677 JY8QFUQ01CSKE5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 660 78.97 169/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-10*01 F 2 8 8 21 8.8.21 [0.17.38.11] CARERRPGGYPNGYHHFYGMDVW in-frame + Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggatatatgttggggactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgtttctgcaaatgaacagtctgagaggtgatgacaccgccacatatttttgtgcgagagagcggcgtccgggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccttggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 16678 JY8QFUQ01DJBYG No results 16679 JY8QFUQ01BAGKP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16680 JY8QFUQ01B2QTP productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 90 to 95 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16681 JY8QFUQ01AYWCC productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16682 JY8QFUQ01CHDMU No results 16683 JY8QFUQ01CADTF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16684 JY8QFUQ01BRQKS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16685 JY8QFUQ01A26WO unproductive Homsap IGHV3-7*01 F 1004 95.87 209/218 nt Homsap IGHJ3*01 F (see comment) 74 60.0 30/50 nt 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcnacgggctactgggccagggaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16686 JY8QFUQ01BQQG5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F (see comment) 693 80.18 174/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-1*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRSPNHNWFDPW in-frame - Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaaattcaataattatgcaatgcactgggtccgccagtctccaagagcggggctgcaatgggtggcggctatatcgactgacggcaataaagaatatcatgcagactccgtgaagggccggctcaccctctccagagacaattcgaggagtacgctgtctctgcaattgcgcaacctgacagctgacgactcggctctgtattattgtgtcagatctcccaaccacaattggttcgacccctggggccagggagccctggtcactgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16687 JY8QFUQ01BUG1S productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16688 JY8QFUQ01AWK2B productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16689 JY8QFUQ01CB9HM productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + tctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16690 JY8QFUQ01BT86M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARAGYCNNGVCYSSYFDFW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtatgaatagtgatggcagtgacataaggtacgcggactccgtgaggggccgattcaccatctccagagacaacaccaagaacacgctgtatctacaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagcgggatattgtaataatggtgtatgctactccagttactttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16691 JY8QFUQ01DOSG1 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - stop codons agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgagtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16692 JY8QFUQ01CJDB1 productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16693 JY8QFUQ01DODI6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CARDSGSSDYTRYDAQDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctctggattcagttttagttcttatggcatgaactgggtccgccaggctccaggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttgcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 16694 JY8QFUQ01AL2LZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16695 JY8QFUQ01AOZD0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16696 JY8QFUQ01BJP4R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccagggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16697 JY8QFUQ01CSZEK No results 16698 JY8QFUQ01A35F3 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16699 JY8QFUQ01A398K unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 894 89.24 199/223 nt 88.79 198/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 X 8.10.X [1.17.38.11] CTTAPKRNLCNG#YFAMDVW out-of-frame + stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 71 of V-REGION: 'CG' (2 nucleotides at position 125 to 126 in the user submitted sequence), (cause frameshift); ctctggatttactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcccccCGtgaaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagcccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgcccccgaaccggtgacggtgtcgtggaactc 16700 JY8QFUQ01CEUFV productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 797 85.32 186/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctgaattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16701 JY8QFUQ01A6SR0 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16702 JY8QFUQ01CW6WC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - cttctggagttcacctttagcagccatatgatgagttgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggagtaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16703 JY8QFUQ01CHC0L productive (see comment) Homsap IGHV1-24*01 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cgggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaAaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatcccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtgggtcatcgcctgcctggtccagggcttcttccccccag 16704 JY8QFUQ01A6ZA7 productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16705 JY8QFUQ01BH8HX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16706 JY8QFUQ01ADJ2M productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16707 JY8QFUQ01DKUO1 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 2 8 7 12 8.7.12 [1.17.38.11] CAVSTTTWGWFDPW in-frame + tctatggtgggtccttcagtggttactactggagctggatccgccagcccccaggggaggggctgcagtggattggaagagtcaatcatagtggaagcaccagctacaacccgtccctcaagagtcgagtcaccatgtcactagacacgtccaagacccacttttccctgaagctgacctctgtgaccgccgcggacacggctgtgtattactgtgcggtgtctactaccacctgggggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 16708 JY8QFUQ01CBMQQ No results 16709 JY8QFUQ01DWSKB productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 1 8 8 11 8.8.11 [0.17.38.11] CVRHTAMERGDYW in-frame + tggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggcccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16710 JY8QFUQ01APCCL productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 925 90.99 202/222 nt 90.54 201/222 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagtggtcgCttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16711 JY8QFUQ01COY09 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 591 95.38 124/130 nt 94.62 123/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 X 11 8.X.11 [1.3.31.11] CAKGGGNGDLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 38 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16712 JY8QFUQ01BY1LM No results 16713 JY8QFUQ01DPHKK unproductive Homsap IGHV4-61*02 F (see comment) 650 77.38 171/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-3*01 F 1 10 7 X 10.7.X [1.17.38.11] CARERDRSIGGAAELDS## out-of-frame + Low V-REGION identity (77,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccaatgtacccatcagtcgtggaggttactactggaattggatccggcaggccgccgggaaggggctggagtggcttggacgtgttgacagtaatggattcgtcaggtacaattcttccctcaaaagtcgcctttctatgtcactagacacgtccaagaatcagatctccctgatattgaggtctgtgatcgccgcagacacggccgtatatttctgtgcgagggagcgtgataggtcgatcggtggagcggcagaacttgactcctgggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16714 JY8QFUQ01CI4TN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [2.17.38.11] CARAYSGPGPYYFDYW in-frame - gcctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16715 JY8QFUQ01AHYKP productive (see comment) Homsap IGHV3-48*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactGgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16716 JY8QFUQ01CWWU6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CANEEVPNDWW in-frame - tctctggattcacgtttagtagccatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggcatcagcataagcggagatagaacatattacgcagactccgtgaggggccgattcaccatctccagagacaattccaggaacactttgtatctacaaatgcacagcctgagagccgaagacacggccacatattactgtgcgaatgaggaggtcccgaatgactggtggggccagggaaccctggtcaccgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16717 JY8QFUQ01AOI9G productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16718 JY8QFUQ01BZKCF productive Homsap IGHV4-4*07 F 885 90.65 194/214 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 1 8 7 18 8.7.18 [1.17.38.11] CTKDVGPLGSDSYWDTLIIW in-frame + ctctggtgactccatcaatactttctactggagctgggtccggcagtccgccgggaagggactggagtggattgggcgtatctattccagtggggacaccaactacaacccctccctcaggagtcgagtcaccatgtcaatagacacgtccaggagtcagttctccctgaggctgacgtctgtgagcgccgcggacacggccatatattactgtacaaaagatgtagggccactgggcagtgactcgtactgggatactcttattatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagactgggaacggtggtcgtcgcatgcctggtccagggcttcttccccca 16719 JY8QFUQ01ARRQT productive (see comment) Homsap IGHV3-9*01 F 855 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.16.38.11] CTRSRVSIDLQPSYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gcctcggattcatctttgatgattttgccatgcactgggtccggcatgctccagggagggcctggagtgggtctcaagtatcaactggaatggtgacgtcaaagcctatgcggactccgtgaagggAccgattcaccgtctccagagacaacgccaagaactccctgtatctgcaaataaacgatctgagagcagaggacacggccttgttttactgcacaagaagtcgtgttagtatcgacttacagccctcctacggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16720 JY8QFUQ01DRAYY No results 16721 JY8QFUQ01CWK7E productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 967 92.44 208/225 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [5.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16722 JY8QFUQ01B7Z4F No results 16723 JY8QFUQ01BN0SJ No results 16724 JY8QFUQ01CB3UD unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 152 58.06 72/124 nt 8 6 X 8.6.X [1.17.9.X] null + No rearrangement found ctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16725 JY8QFUQ01AGLFX unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRGLY*WCMLCR#DFW out-of-frame + stop codons cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggcttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16726 JY8QFUQ01B5K0M No results 16727 JY8QFUQ01AIXHU productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16728 JY8QFUQ01AK0L3 No results 16729 JY8QFUQ01AONH0 No results 16730 JY8QFUQ01CE65C No results 16731 JY8QFUQ01A1DN4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1081 99.54 218/219 nt 98.63 216/219 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [2.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcctctggattcaGccttcagtagttatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggaaattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16732 JY8QFUQ01DFSFI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 6 12 8.6.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) ttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccgaaggtcttcccgctgagcctcgacagcacccccctaaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccc 16733 JY8QFUQ01BM4Y9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 833 87.16 190/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccaccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaac 16734 JY8QFUQ01C8VAK No results 16735 JY8QFUQ01CSMWR unproductive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKLADTGEWSNRIFI#W out-of-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatctttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16736 JY8QFUQ01AD0EQ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [2.17.38.11] CGKTSFRCLRLTLTTG in-frame - gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtggaaagacctctttcaggtgtctacgacttactttgactactggggccgggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 16737 JY8QFUQ01AVK32 productive Homsap IGHV3-9*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcacctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattacttggaacagtggtaggataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgc 16738 JY8QFUQ01DFZ3Q unknown (see comment) Homsap IGHV4-61*04 F (see comment) 347 62.21 135/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (62,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16739 JY8QFUQ01DMUUW unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [2.17.38.11] CAGDLTGGSVLL*Q*WFK#YW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaTgcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16740 JY8QFUQ01AY47V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 770 100.0 155/155 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 X 8 18 X.8.18 [X.5.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - tggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16741 JY8QFUQ01ASIFV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKLGVAATTWNFFDYW in-frame - gcctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16742 JY8QFUQ01B6CI4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 397 76.64 105/137 nt 75.91 104/137 nt 8 8 X 8.8.X [1.16.11.X] null - No rearrangement found Low V-REGION identity (76,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaagggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 16743 JY8QFUQ01DLYHZ productive (see comment) Homsap IGHV3-7*02 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaagGggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16744 JY8QFUQ01BYUC2 No results 16745 JY8QFUQ01DEWGA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 213 80.3 53/66 nt 8 X X 8.X.X [1.12.X.X] null + No rearrangement found Low V-REGION identity (80,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggcttcttcccc 16746 JY8QFUQ01AFTH6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggaactca 16747 JY8QFUQ01C151E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16748 JY8QFUQ01CLZES productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16749 JY8QFUQ01B8BL9 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDSRHSASGSYSDYW in-frame - gcgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16750 JY8QFUQ01A5HW4 productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaaccgaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaacggtgacggtgtcgtggaactca 16751 JY8QFUQ01BMJK2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 16752 JY8QFUQ01C5LMS productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16753 JY8QFUQ01BKOF3 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 3 8 8 19 8.8.19 [1.17.38.11] CARLPFIVVVTGAFLGHFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggGggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16754 JY8QFUQ01CZSU7 productive Homsap IGHV3-66*02 F 958 93.98 203/216 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [2.17.38.11] CARDSPYSSGWSDGFDVW in-frame - gcctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16755 JY8QFUQ01CRBJ3 productive (see comment) Homsap IGHV4-39*02 F 839 86.88 192/221 nt 85.97 190/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctctggtgaccccatcggcaacactgcttactcctgGgggctggatccgccagcCccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 16756 JY8QFUQ01AX1O9 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 633 77.1 165/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01AX1O9 ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16757 JY8QFUQ01DFJVB productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + ctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16758 JY8QFUQ01BDW17 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16759 JY8QFUQ01ATK2N productive Homsap IGHV3-66*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [1.17.38.11] CARQTAPFGYFEDW in-frame + ctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 16760 JY8QFUQ01C8T0U productive (see comment) Homsap IGHV3-7*01 F 869 88.99 194/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'GA' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift); cctctaaattcaccTtttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaaagcagGAttgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16761 JY8QFUQ01B8FEW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16762 JY8QFUQ01CPXL5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16763 JY8QFUQ01BW489 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16764 JY8QFUQ01BJ3YF No results 16765 JY8QFUQ01AOGNY productive Homsap IGHV3-7*01 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - gcctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaagcggacatcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16766 JY8QFUQ01B2DU2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16767 JY8QFUQ01DOOXO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16768 JY8QFUQ01DAZL5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16769 JY8QFUQ01COUPG No results 16770 JY8QFUQ01AW8M2 unproductive Homsap IGHV3-48*01 F 1075 99.54 215/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASIFWSGSPG##YYYGMDVW out-of-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgattttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16771 JY8QFUQ01AAUZH productive Homsap IGHV4-59*03 F 890 90.7 195/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + tctcgggtgactccatcactcctaactcctggagctggatctggcagcccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 16772 JY8QFUQ01B52T3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16773 JY8QFUQ01CIUWJ No results 16774 JY8QFUQ01AMBVG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + ctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagccacccagccaggatgggaagcntggtccatgcgctgcctgggtccaggcttcttcccc 16775 JY8QFUQ01B7S7G unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16776 JY8QFUQ01BI8UY productive Homsap IGHV3-7*01 F 1012 96.76 209/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + tctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16777 JY8QFUQ01CE1S4 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16778 JY8QFUQ01BRK0D No results 16779 JY8QFUQ01CN7M5 productive Homsap IGHV3-11*04 F, or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 972 92.48 209/226 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [4.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactcag 16780 JY8QFUQ01AUTF4 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + tctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16781 JY8QFUQ01CV876 productive (see comment) Homsap IGHV3-48*01 F (see comment) 754 84.04 179/213 nt 83.1 177/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16782 JY8QFUQ01C67G0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16783 JY8QFUQ01CIUCD productive Homsap IGHV3-66*02 F 912 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggattctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcggttatttatgccgatggaagtacattctacgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacgctcaatcttcaaatgagcagcctgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16784 JY8QFUQ01BGJ2O productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.16.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcacgtttggcagccacgccatgagctggtccgccaggctccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16785 JY8QFUQ01AJ3Q0 unproductive Homsap IGHV3-21*04 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ5*01 F 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARAVSNQVDV## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); cctctggattcgccGttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagAttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgaatgcctggtccagggcttcttcccccca 16786 JY8QFUQ01CBCM8 productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16787 JY8QFUQ01AT57K No results 16788 JY8QFUQ01BJ6RF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 820 86.3 189/219 nt 85.39 187/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [2.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gcctctggattcagatttagcagctatgccaGtgagctgggtccgccagactccaggaaAaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16789 JY8QFUQ01CJZTY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 143 to 143 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccCagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaaggggcccatcggtcttacccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16790 JY8QFUQ01B4T2J productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 10 7 13 10.7.13 [1.16.38.11] CVRHHYGGSLNFKYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctccggtgcctccatcagtagtaatagtcactactgggcctggatccgccagtcccagggaaggtcctggagtggattgggagtctctattatactgggagcaccctctacaacccgtccctcaagagtcgactcaccacatctgtggacacgtccaagaatctgttttccctgaacctgagtgctgtgaccgccgcagacacggctgtatattactgtgtgagacaccactacggtggttctctgaattttaagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16791 JY8QFUQ01ACU3I unproductive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CATIVPSSVTALINDQGRFYFDH## out-of-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16792 JY8QFUQ01A7831 unproductive (see comment) Homsap IGHV1-8*01 F (see comment) 512 71.16 153/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - stop codons no junction found Low V-REGION identity (71,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctggatacaccttcaccaattatgatatcaactgggtacgacaggccagtggaaaagggcttgagtggatgggatggctgacccctaagagtagtaacacaggctctgtgcagaagttatagggcagagtcaccatgaccaggacttggagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16793 JY8QFUQ01BJOLZ unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 X 9.7.X [1.17.38.11] CARGETDC##YYFDYW out-of-frame + stop codons tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaactgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16794 JY8QFUQ01CJBTL productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 98.16 213/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaagGgggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaaggGgccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16795 JY8QFUQ01DGWEK productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 927 90.27 204/226 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD5-24*01 ORF 3 8 10 17 8.10.17 [2.17.38.11] CSRGLGDGYNLGYHALDIW in-frame - agcttctggattcagttttggtgattattctatgatctggttccgccaggcaccggggaaggggctggagtgcgtaggtttcattagaagcagagcatatggtgggacaacacaatacgccgcgtctgtgaaagacagattcaccatctcaagagatgatcccaaaggcatcgcctatttgcaaatgagcagtctgaaagtcgacgacacaggcgtgtatttttgtagtcggggattaggcgatggctacaatctgggttatcatgcccttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16796 JY8QFUQ01AY3LZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 1 8 7 9 8.7.9 [2.17.38.11] CARDTWPTSYW in-frame - tgtctctggtggctccatcagtagttactactggagctggatccggcagccccacgggaagggactggagtggattgggtatatctattacactgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatacctggccaacttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16797 JY8QFUQ01CEZG1 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16798 JY8QFUQ01A5YDK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame + ctctggattcatcttcacaagatatgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtcgcatctatcagtggtagtggtattacaacaaaatacgcagacgccgtgaagggccggtttaccatctccagagacagttccaggaacactctgttcctgcacatgagtggcctgagagccgaggacacggccgtgtattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16799 JY8QFUQ01C2E1B No results 16800 JY8QFUQ01APNKV No results 16801 JY8QFUQ01CCL84 No results 16802 JY8QFUQ01CBM76 unproductive Homsap IGHV3-7*01 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CARREHNWDTVLALAAQ#DLW out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'TAA' (3 nucleotides at position 83 to 85 in the user submitted sequence), (do not cause frameshift); ctctggattcagtatttataattattggatgaattgggtccgccaggctccagggagggggctggagtgggtggccagcattTAAaggcagacgggaactgagaagacgtttggggactctgtgaagggccgattctccatctccagagacaacgccaggaactcagtggatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcgaggagggaacacaactgggatactgtgctagccctagctgcccaactgacttgtggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16803 JY8QFUQ01CEJB8 unproductive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CARVRARSNSSPRPQLVR#PW out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccggaaagggaccggagtggattgggcatatctatagtagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcggacacggccgtgtattactgtgcgagagtgagggcgcgcagtaatagctcaccccggccacagctggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccggaaccggtgacggtgtcgtggcaactc 16804 JY8QFUQ01DDP0S No results 16805 JY8QFUQ01C0G1T unproductive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F (see comment) 96 63.16 36/57 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CGKDMRPGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctgggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16806 JY8QFUQ01BK7A2 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 434 66.06 146/221 nt 64.71 143/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null + stop codons no junction found Low V-REGION identity (66,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 30 of V-REGION: 'CCTG' (4 nucleotides at position 15 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); tctcgggtgactccCCTGagtgccagtagtagTtttctactGggggctgggtccgccagcccccagggaagggactggagtggattgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatactgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16807 JY8QFUQ01AYH1B unknown (see comment) Homsap IGHV3-74*03 F 135 55.56 75/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16808 JY8QFUQ01B2A34 No results 16809 JY8QFUQ01AVBM5 productive Homsap IGHV3-11*01 F 846 88.02 191/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIKLGDWCFDLW in-frame + ctctgaaatcaccttcagcgaccactacatgagctggatccgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16810 JY8QFUQ01BPA2X No results 16811 JY8QFUQ01APVTX No results 16812 JY8QFUQ01CSS61 unproductive Homsap IGHV3-72*01 F 1079 98.21 220/224 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccacgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16813 JY8QFUQ01AUKXZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGYHGPFDS## out-of-frame + ctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgacacatactactcagactccgtgaggggccggttcaccatctccagagacaacgccaagaacacgatgtatctgcaaatgaacaccctgagagacgaggacacggccgtctatttctgcgcgaaaggttaccacggcccctttgactcttggggccggggcaaccctggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccanatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16814 JY8QFUQ01C7A52 productive (see comment) Homsap IGHV3-11*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F (see comment) 211 88.68 47/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIRLGDWCFDIW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgaGtttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctggggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16815 JY8QFUQ01DOK15 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame - tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16816 JY8QFUQ01CIXMG No results 16817 JY8QFUQ01ALCZK unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL#DYW out-of-frame - stop codons ctctggtgggtccttcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16818 JY8QFUQ01BIP93 unproductive Homsap IGHV3-21*04 F 962 94.42 203/215 nt Homsap IGHJ2*01 F (see comment) 85 62.26 33/53 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [0.17.38.11] CGKDMRPGGMD#LG out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctggattcaccttcaggacctataccacgaactgggtccgccaggctccagggaaggggctggagtgggtctcctccattagtagtagtagtagttacatatattacgcagactcagtgaagggccgcttcaccatctccagagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctgggggccagggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 16819 JY8QFUQ01B6JTT productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16820 JY8QFUQ01AZOI4 No results 16821 JY8QFUQ01CK28T productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16822 JY8QFUQ01CJBIC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame - cctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16823 JY8QFUQ01CNU48 unproductive Homsap IGHV3-48*02 F 871 90.14 192/213 nt 89.2 190/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [0.16.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) tggattcaccttcgacagatacagtatgaactAgggtccgccaggctccaggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16824 JY8QFUQ01BG922 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16825 JY8QFUQ01AA9O7 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16826 JY8QFUQ01DELBD No results 16827 JY8QFUQ01DDFZD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 796 85.25 185/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cnctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16828 JY8QFUQ01CE00X productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame + ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16829 JY8QFUQ01CIQNC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16830 JY8QFUQ01CAD8M productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16831 JY8QFUQ01B1XFK unproductive (see comment) Homsap IGHV3-7*01 F 1026 97.24 211/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgacaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16832 JY8QFUQ01CT5BN productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16833 JY8QFUQ01CUQLX productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 888 91.47 193/211 nt 91.0 192/211 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [0.16.38.11] CTRELRLAAARDGVDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaagggctggagtgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16834 JY8QFUQ01BEBK3 productive Homsap IGHV3-9*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame - ctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16835 JY8QFUQ01BR29F No results 16836 JY8QFUQ01CTB5I productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16837 JY8QFUQ01C8J0R productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame - ctctgacgttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16838 JY8QFUQ01AYT1Z productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16839 JY8QFUQ01CIXAF No results 16840 JY8QFUQ01A3ZB9 productive Homsap IGHV1-3*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGESLGGDYFDYW in-frame + tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16841 JY8QFUQ01BXCLW unproductive Homsap IGHV3-23*03 F 905 90.83 198/218 nt 89.45 195/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD3-3*01 F 2 8 7 X 8.7.X [2.17.38.11] CTRELRLAAARDGVDIL# out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) cagcctctggattcccctttagcaactatgacatgagctgggtccgccagggtccagggaaAggggctggagtgggtcGtcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacattttgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16842 JY8QFUQ01CIUKG No results 16843 JY8QFUQ01DM9NE productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatnacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16844 JY8QFUQ01B4HAX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggc 16845 JY8QFUQ01DI195 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 16846 JY8QFUQ01AQ07I unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 16847 JY8QFUQ01DWTK3 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [0.16.38.11] CAKDQSCIVGPCGF*LL# out-of-frame - stop codons in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcaccctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg 16848 JY8QFUQ01C32DT productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaatcggtgacggtgtcgtggaactc 16849 JY8QFUQ01DQZLY No results 16850 JY8QFUQ01A9S5C unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*04 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*04 F (see comment) 302 65.03 106/163 nt 8 7 X 8.7.X [1.17.21.X] null + No rearrangement found Low V-REGION identity (65,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggttcaccatcactcactactccatggcctgggtccgccaggctccggggaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 16851 JY8QFUQ01BBJ5E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 933 93.84 198/211 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 8 10 7.8.10 [X.17.38.11] CARGGLEPVDYW in-frame - attcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16852 JY8QFUQ01ALC3A unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 617 74.89 170/227 nt 74.45 169/227 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-10*01 F 2 9 9 17 9.9.17 [2.17.38.11] CAREVTTRPPSYYKGLDVW in-frame - stop codons Low V-REGION identity (74,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 2 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) catctccggggacaatttgtagtaagacagctgcttgaattggatcgagacagccctcatcgggcggccttgaatggctgggaagggcatatttcaggtccaagtggtacattgaatatggagactctgtgaggggtcgcgttacgttcattggagacacactgacgaaccaattctccttgcacttggcctccgtgactcccgacgactcggctgtctatttctgtgcaagggaggtgaccacacggcccccctcctattataaaggtctggacgtctggggccaagggaccacagtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16853 JY8QFUQ01C1V1D productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 16854 JY8QFUQ01AVEH8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.16.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctggattcacgtttggcagccacgccatgagctggtccgccaggctccagggaaggggctggagtacgtctcaattgttactgatagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16855 JY8QFUQ01A2XAO unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 93 52.27 69/132 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons cctctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 16856 JY8QFUQ01BJ2WG unproductive (see comment) Homsap IGHV3-9*01 F 792 85.25 185/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CGRIAKPGLGALDL## out-of-frame + stop codons cgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggcccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgctgcctggtccagggcttcttccccca 16857 JY8QFUQ01DP9CB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 904 91.2 197/216 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16858 JY8QFUQ01AHTPV productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 85.19 184/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.16.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) tgtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtgattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16859 JY8QFUQ01BGHJU productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [3.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); caggtctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16860 JY8QFUQ01CNZ0D productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16861 JY8QFUQ01BWQ4Q productive (see comment) Homsap IGHV3-48*01 F (see comment) 764 84.19 181/215 nt 83.26 179/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16862 JY8QFUQ01AV57N productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16863 JY8QFUQ01DQJEG No results 16864 JY8QFUQ01BB2GZ productive (see comment) Homsap IGHV3-48*01 F 1065 100.0 214/214 nt 98.6 211/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.16.37.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 98 of V-REGION: 2 nucleotides (from position 198 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccgGccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16865 JY8QFUQ01C9OHK productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 858 89.25 191/214 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - ctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16866 JY8QFUQ01BOR1E productive (see comment) Homsap IGHV3-9*01 F 986 94.95 207/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.16.38.11] CAKSGTYSSSSGHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gcctctggattcaactttaataaGttatgccatgcactggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccCctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16867 JY8QFUQ01ADSUP unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 140 53.04 96/181 nt 8 6 X 8.6.X [1.17.27.X] null + No rearrangement found cctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccgaccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16868 JY8QFUQ01CJ5K3 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 979 93.69 208/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 1 8 10 X 8.10.X [1.17.38.11] CTTDPRYFWGA#FDYW out-of-frame - tctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16869 JY8QFUQ01BPA36 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGTYLYYFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 16870 JY8QFUQ01BCCSR No results 16871 JY8QFUQ01B2TPF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKNLRLGHSYFYNALDVW in-frame + ctctggtggcctcatcagtaattactattggacctggatccggcagcccccaggaaagggactggagtggattgggaacatctattacagtgggagcgccacctacaacccctccctcaagagtcgagtcaccatatcaatagactcgtccaagaaccagttctccctgaggctgaccgctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaacttacgattgggtcacagttacttctacaacgctttggacgtatggggccaagggaccacggtcaccgtcgcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16872 JY8QFUQ01AX55P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame - tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16873 JY8QFUQ01B8BPC productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatCggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16874 JY8QFUQ01A152R productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 915 90.91 200/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 16875 JY8QFUQ01DMUBK productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16876 JY8QFUQ01ACD72 No results 16877 JY8QFUQ01C22P8 productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16878 JY8QFUQ01B90UJ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) cctcctggattcaccCtttggttattatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16879 JY8QFUQ01BACIJ No results 16880 JY8QFUQ01AG35D unproductive (see comment) Homsap IGHV3-7*01 F 975 95.33 204/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.37.11] CAKGGW*R##LDYW out-of-frame + stop codons in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaatttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 16881 JY8QFUQ01CWCEK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 734 82.11 179/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARGGTDFDYW in-frame + Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggatttacatttagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgaggggccgcttcaccatctctagagacgacgccaagaattcactttatctgcagatgaacaacctgagaggcgaggacacggctgtctatttttgtgcgagaggggggactgattttgactattggggccagggaaccctggtcaccgtctcctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 16882 JY8QFUQ01AHEDS unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 786 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.17.38.11] CATLRGGY#FDYW out-of-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttaTacttaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16883 JY8QFUQ01CTA32 No results 16884 JY8QFUQ01CNHYC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16885 JY8QFUQ01B8T6Y productive Homsap IGHV3-9*01 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + ctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtggtaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16886 JY8QFUQ01A46ML unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16887 JY8QFUQ01CGLQI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 156 78.43 40/51 nt 76.47 39/51 nt 7 X X 7.X.X [1.8.X.X] null + No rearrangement found in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) ctcagggttcgttttgagaaatacgccatgagttgggtccgccaggcccca 16888 JY8QFUQ01AP1AZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16889 JY8QFUQ01DB81Q productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame - tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16890 JY8QFUQ01BN2TK No results 16891 JY8QFUQ01CNQ0R unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 265 100.0 53/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 16892 JY8QFUQ01DFJ66 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 817 87.32 186/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 7 12 8.7.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16893 JY8QFUQ01C8F4Z productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD5-18*01 F 3 8 8 9 8.8.9 [X.17.38.11] CALGHNYGSAW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'CT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift); ggattcacctttgatgaCTtttgggcatgagctgggtccgccaagttccagggaaggggctggagtgggtctgtggttatgcttggattggtggtgccccaacttatgcagcctctgtgaagggccgattcaccatctccagagacaacgccaagagctccctgtatctgcaaatgaacagtctgagagccgaagacacggccttgtatcactgtgcgctgggacacaattatggtagtgcctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16894 JY8QFUQ01B3TRM unproductive (see comment) Homsap IGHV4-39*03 F 933 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-22*01 F 1 9 7 X 9.7.X [1.17.38.11] CARSITLTVVVMND##FDVW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 26 in the user submitted sequence), (cause frameshift) tctccggtggctccatcaacagtagaattattattggggctggatccgccagAcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgccttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16895 JY8QFUQ01AGSEB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ3*02 F 250 100.0 50/50 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKRLEGVADDAFDIW in-frame - cctctggattcacctttagcagctatgccatgggctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtgggagtggtcggagcacatactacgcagactccgtgaagggccggtacaccatctccagagacaattccaagaatacgatgtctgtgcaaatgagcagcctgagagtcgaggacacggccatatattattgtgtgaaaaggttggaaggagtggctgatgatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16896 JY8QFUQ01BBGFU productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16897 JY8QFUQ01AA0HG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccggggaaggggctggtgtgggtctcacgtactaacacgggggggactaacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16898 JY8QFUQ01AR4WB productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16899 JY8QFUQ01A6RG8 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16900 JY8QFUQ01ASZ0M productive (see comment) Homsap IGHV4-59*03 F 786 85.51 183/214 nt 84.58 181/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.37.11] CARGRTVVTVVDYVDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 109 in the user submitted sequence), (cause frameshift) tctctggtgactccattagtggttactattggacgtggatccgacagcgcccagggatgagcctggagtggattggacaagtccattacactgggagcaccaagtacagccctccctcaagagtcgagtcaccatttctgttgacatgtccaagaaccCaattcaccctcatcttgacctctgtggccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttgttgactacgttgacttttggggtcagggagtcctggtcaacgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16901 JY8QFUQ01DSF94 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 185 89.13 41/46 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found gctctggattcaccttcagtaagtatgccatgagctgggtccgcca 16902 JY8QFUQ01DI96K unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDTGQWKDFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggcccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 16903 JY8QFUQ01C5PFO productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 942 92.27 203/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [2.17.38.11] CARGMATAESW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) agcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16904 JY8QFUQ01AYM8A No results 16905 JY8QFUQ01AZDJV No results 16906 JY8QFUQ01DRJD4 No results 16907 JY8QFUQ01CHKNS No results 16908 JY8QFUQ01CZMUC No results 16909 JY8QFUQ01CA76U productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 970 93.24 207/222 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16910 JY8QFUQ01AZZIB unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 206 54.71 122/223 nt 54.26 121/223 nt 7 6 X 7.6.X [7.17.36.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (6 AA in JY8QFUQ01AZZIB ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (54,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) aagatctcctgtgcagcctctggattcagtttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16911 JY8QFUQ01DB0RP No results 16912 JY8QFUQ01DDJMW productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 853 89.2 190/213 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16913 JY8QFUQ01B3LZM No results 16914 JY8QFUQ01BIQIL No results 16915 JY8QFUQ01CKBOH productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctgggttcacctttaggagctattggatgaactgggtccgccaGggctccagggaaggGggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccc 16916 JY8QFUQ01ANO20 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 813 86.92 186/214 nt 85.51 183/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD1-26*01 F 3 8 7 11 8.7.11 [1.17.38.11] CATEREGGWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggGaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagactcagtgaagggccgattcaccgtctccagagacaacgccaagaaatcattgtatctacaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgacagagagggaaggtggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16917 JY8QFUQ01BZZ70 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 10 X 8.10.X [1.17.38.11] CVVDIPEVGVG#FDYW out-of-frame + ctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttggtgtggggaatttgactactggggccagggagccctggtttccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16918 JY8QFUQ01B4ZWU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSDYTRYDAQDLW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcagtttggatacttatggcatgaactgggtccgccaggctccaggggaggggctggagtgggtctcattcattaatagtgttagcagttacaaatattatgtggactcagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacctctggggccaagggaccgcggtcaccgtctcttcagcctccacaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 16919 JY8QFUQ01CQZKO unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16920 JY8QFUQ01BGV5H unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 981 94.06 206/219 nt 92.69 203/219 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.16.38.11] CARRGRCG*#YWYFDLW out-of-frame - stop codons in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctctagtgactccatcagcagtactaattactactggggctggatccgccagccccagggaaggggctgagtggattgggantaCtntatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16921 JY8QFUQ01BF8CL productive Homsap IGHV4-61*02 F 1037 96.83 214/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARGPKYYYDSSGFEDLW in-frame + tctctggtggctccatcagcagtggtcgttactactggagctggatccggcagcccgccgggaagggactggaatggattgggcgtatttataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagctctccctgaagttgagttctgtgaccgccgcagacacggccgtatattactgtgcgagaggtcccaagtattactatgatagcagtggtttcgaagacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16922 JY8QFUQ01APSCL productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1039 98.15 212/216 nt 97.69 211/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 7 12 8.7.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctgggttcaccgtcagtagcaactacatgagctGgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16923 JY8QFUQ01CK36G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 16924 JY8QFUQ01DW930 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatTggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16925 JY8QFUQ01BEXOG productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt 85.14 189/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16926 JY8QFUQ01ALFPF productive Homsap IGHV4-61*02 F 920 90.95 201/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16927 JY8QFUQ01BA8EB No results 16928 JY8QFUQ01B6PBL unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRGGSQWGLQVG#FDYW out-of-frame - stop codons cctctggattcaccttcagtggttactggatgcactgggtccgccaagctccaggaaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagaggggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacgattccccgaagccggtaacggtgtcgtggaactcagg 16929 JY8QFUQ01ASK4D productive Homsap IGHV4-61*02 F 879 88.69 196/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVPTG in-frame - tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttntgtgcgagagattttggaggttcctacaatttagtgcctactggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16930 JY8QFUQ01A82IN productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 845 88.37 190/215 nt 87.91 189/215 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASLVTINDNGDYTWAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tggatggtgggtccttcagtaataagtattggagttggattcgccagtTccccagggaaggggctagagtggattggagaaatcaaccaaagtggaagcaccaactacaatccgtccctcatgagtcgagtcaccatctccatagacacgtccaagatgcagttctccctgaagttgacctctgtgaccgccgcggacacggctgtctattattgtgcgagtttagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctgggcccaagggacaatggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 16931 JY8QFUQ01B71VU productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 16932 JY8QFUQ01CR93B productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16933 JY8QFUQ01CM1WR No results 16934 JY8QFUQ01DPGK3 productive (see comment) Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 96.79 211/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcaggtttagcatctattgGgatgagctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 16935 JY8QFUQ01CHPNW unknown (see comment) Homsap IGHV3-49*02 F, or Homsap IGHV3-49*04 F 92 50.0 92/184 nt 49.46 91/184 nt 8 7 X 8.7.X [1.16.28.X] null + No rearrangement found in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttctcacactatgaactgggtccggcaggctccagggaaggggccgagtgggtcatcatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16936 JY8QFUQ01C0J7S productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + cctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16937 JY8QFUQ01AVP0N productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 912 92.06 197/214 nt 91.12 195/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARRDVGSHAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tggatacaAtttttaactacgactggatcgGgctgggtgcgccagatgcccgggaaaggcctggagtggatggggatggtctatgttggtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16938 JY8QFUQ01CQHI2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.37.11] CAKDGARGGGSCFNSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16939 JY8QFUQ01BGJ69 productive (see comment) Homsap IGHV3-7*01 F 977 94.5 206/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); tctctggattcaccGtttagtagggtttggatgacctgggtccgccagGggtccagggaaGggggctggagtgggtggccaacataaAagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 16940 JY8QFUQ01BEBWZ No results 16941 JY8QFUQ01DNHLW unknown (see comment) Homsap IGHV3-11*01 F (see comment) 628 77.0 164/213 nt 76.53 163/213 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DNHLW ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (77,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtgactactacatgagttgggtccgccaggGctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16942 JY8QFUQ01BEJ4M No results 16943 JY8QFUQ01CHMQ3 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16944 JY8QFUQ01DMX02 productive Homsap IGHV3-21*04 F (see comment) 662 78.44 171/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16945 JY8QFUQ01DKEJS productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'ACCCCCA' (7 nucleotides at position 81 to 87 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcaACCCCCAaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16946 JY8QFUQ01BZ0PJ unknown (see comment) Homsap IGHV3-69-1*02 P 1029 98.13 210/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found however the closest V is a pseudogene The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctagattcaccttcagtgagtactacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattaggagtagtagtaccatatactacgcagactctatgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagacgcaatgaattcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16947 JY8QFUQ01C5PN0 productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16948 JY8QFUQ01AEV7X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16949 JY8QFUQ01CV10S unknown (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 814 97.65 166/170 nt 8 7 X 8.7.X [1.17.23.X] null + No rearrangement found ctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagcggtggtaccacattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc 16950 JY8QFUQ01C3YA5 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*06 F 905 90.83 198/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggtctggaatggttggcaatgatatggtatgatggaaataaaaaatactacgcagactccgcgacgggccgattcaccatctccagagacaattctgagtacacgctgtctcttcaaatgaacagcctgagagtcgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 16951 JY8QFUQ01CXNBM productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1101 99.55 222/223 nt 98.65 220/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-7*01 F 3 8 10 13 8.10.13 [1.16.38.11] CTTISIWNYMFEGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggttggccgtattaaaagcaaaactgatggtgggacaacagactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcaaaaaaTcacgctgtatctgcaaatggacagcctgaaaaccgaggacacagccgtgtattactgtaccacaatttcgatctggaactatatgtttgagggctactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgcccccaaaccctt 16952 JY8QFUQ01B97DO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - cctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16953 JY8QFUQ01AE8MS No results 16954 JY8QFUQ01B8TQS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [0.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) tggattcagcttcagtacctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16955 JY8QFUQ01BBJ0Z No results 16956 JY8QFUQ01B5MTP productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16957 JY8QFUQ01AU2SR No results 16958 JY8QFUQ01CNXIW No results 16959 JY8QFUQ01B1ENW No results 16960 JY8QFUQ01AWY0D No results 16961 JY8QFUQ01C9KNG unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F (see comment) 804 84.75 189/223 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD3-10*01 F 1 8 10 X 8.10.X [1.17.38.11] CARIWEPSITFLHT#FDVW out-of-frame + stop codons Low V-REGION identity (84,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttcggggttcacctttggtgactatgctatcagttggttccgccaggctcctgggaaggggctggagtggattgctctccttaggagcaaaccttataattcaccaacacaattcgccacgtctgtgaaaggccgattcactgtctcaagagatgactcggaaagtgtcgcctatctgcacatgaacagcctgcaaaccggggacacagccgtgtattattgtgccagaatatgggaaccaagtattactttccttcatacattttgatgtctggggccgagggacacgggtcaccgtttcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16962 JY8QFUQ01B2SXL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgcaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16963 JY8QFUQ01BO8QL unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga 16964 JY8QFUQ01CZ42C unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 961 94.84 202/213 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 9 7 X 9.7.X [X.17.38.11] CARGETDCRVLL*LL# out-of-frame + stop codons ggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaactgactgccgagtactactttgattactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 16965 JY8QFUQ01BT0XX productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.77 193/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKINNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaatcaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccccgag 16966 JY8QFUQ01B89QH productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16967 JY8QFUQ01CD9SW productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 885 90.65 194/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [0.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame - tggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16968 JY8QFUQ01BMYLY No results 16969 JY8QFUQ01C4D2U No results 16970 JY8QFUQ01CYV65 productive (see comment) Homsap IGHV3-7*01 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARVRGYYGGQYFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 27 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); agcctctgGgattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16971 JY8QFUQ01BLAYF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-11*01 ORF 3 8 8 12 8.8.12 [1.17.37.11] CARHLTPEDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 169 in the user submitted sequence), (cause frameshift) cctctggattcacctttgacaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtgttagtggtcctggtggtaacacataccacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacatgctgttctgcaaatgaacagtctgagggtcgaggacacggccgtttattactgtgcgagacacctgactccagaggatgcttttgatatttggggccaagggacaatggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16972 JY8QFUQ01CROU6 productive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16973 JY8QFUQ01CCGF5 productive (see comment) Homsap IGHV3-11*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggaAtttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16974 JY8QFUQ01DHQXI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1013 96.33 210/218 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 16975 JY8QFUQ01C10RQ unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16976 JY8QFUQ01BYF03 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctgtcaaggactanttcccccgaaccggtgacggtgtcgtggaactc 16977 JY8QFUQ01BIUGN No results 16978 JY8QFUQ01CVL82 unproductive (see comment) Homsap IGHV3-48*03 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDLNWSFDS# out-of-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); cctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctgtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccctaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 16979 JY8QFUQ01BHSLV No results 16980 JY8QFUQ01B0PWQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16981 JY8QFUQ01AQ6QH productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcctctggatcacctttggttattgatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16982 JY8QFUQ01AN7XN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); tctggattcaccttCcgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16983 JY8QFUQ01CH91E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16984 JY8QFUQ01BBZE4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 7 13 8.7.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaAaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16985 JY8QFUQ01CHJ2M unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtctcccctgcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16986 JY8QFUQ01A8NJV unknown (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F or Homsap IGHV1-NL1*01 P 80 55.7 44/79 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagag 16987 JY8QFUQ01BHPWK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1014 95.91 211/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) agcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16988 JY8QFUQ01CLQEI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16989 JY8QFUQ01B7QCF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 9 8.7.9 [1.17.38.11] CARGGSYFWDW in-frame - tctctggtggctccaccaataataactactggacttggatccggcagcccccagggaagggaatggagtgggttgggtatgtcaattatgctgggaccaccaactacaacccctccctcaagagtcgagtcactatttcagtggactcgtccaagaaccagttctccctgagggtgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggcagctacttctgggactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16990 JY8QFUQ01AARUN productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1062 96.9 219/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - taccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16991 JY8QFUQ01CTI25 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 16992 JY8QFUQ01AI9DI productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 855 88.48 192/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CTRVGTFNWFGPW in-frame + ctctggattcaactttgcggattatggcttgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaatggcaagaagtccctatatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtacgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 16993 JY8QFUQ01B4I9E productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 16994 JY8QFUQ01B9LAR productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) cctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccCctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 16995 JY8QFUQ01C0KUX No results 16996 JY8QFUQ01BVI82 productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggAagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 16997 JY8QFUQ01A1MBV productive (see comment) Homsap IGHV3-9*01 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDVTSESHFFALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctcgggattcaagtttgatgaatatgccatgcactGgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 16998 JY8QFUQ01B4G9N productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 16999 JY8QFUQ01ACYCV unproductive (see comment) Homsap IGHV3-48*02 F 976 94.91 205/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGGG*PVFS#YYSGLDVW out-of-frame - stop codons tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcggggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17000 JY8QFUQ01CMDEJ productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17001 JY8QFUQ01C7ERG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVMREHYYGAGNYPSGGN#EVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 78 of V-REGION: 'G' (1 nucleotides at position 139 to 139 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccaGtttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcagccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctcgggggggaatggaagtctggggccaggggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17002 JY8QFUQ01CON7Y productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + ctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17003 JY8QFUQ01AQ9C2 No results 17004 JY8QFUQ01CRQ7V No results 17005 JY8QFUQ01BFROD productive Homsap IGHV4-39*02 F (see comment) 757 83.11 182/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17006 JY8QFUQ01BVO9P No results 17007 JY8QFUQ01C7DQY unproductive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 821 85.97 190/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 10 7 12 10.7.12 [1.17.38.11] CARAGGWTPYFDSW in-frame - stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'T' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaattactactggaactggatccgccaAttccccagggaagggactggagtggattggatatatctactaTgcttggggccaccaacctcgcctcctccctcaagaaccgagtcaccatatcgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccatatattactgtgcgagggccggtggctggaccccctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17008 JY8QFUQ01C7802 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17009 JY8QFUQ01A3Y4U productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17010 JY8QFUQ01A2O5S No results 17011 JY8QFUQ01CJPZ5 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 975 93.27 208/223 nt Homsap IGHJ3*01 F 142 76.0 38/50 nt Homsap IGHD2-15*01 F 1 8 10 X 8.10.X [1.17.38.11] CAADGCPGGTCYHGFD#VG out-of-frame - ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccaggaaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtgggggcccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17012 JY8QFUQ01CW8RX productive (see comment) Homsap IGHV3-11*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggGggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17013 JY8QFUQ01AMCC5 productive (see comment) Homsap IGHV4-59*03 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.37.11] CARGLYYYTSGYPHDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgactccatcaatgcttactattggagctggattcggcagTcccccagggaagggactggagtggattggacatgtctattatagtgggagcaccaactacaaccctccctcaagagtcgagtcaccatatcagtagacatatccaagaaccaattctccctgaagctgaactctgtgaccgctgcggacacggccgtgtatcactgtgcgcgggggctctattattatactagtggttatccccatgatgcttttgatgtctggagccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17014 JY8QFUQ01B9QYJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtc 17015 JY8QFUQ01B9BWL No results 17016 JY8QFUQ01CLHDB productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccctaaggtcttcccgctgagcctcctgcagccacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17017 JY8QFUQ01CW4A7 No results 17018 JY8QFUQ01CXPRB productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17019 JY8QFUQ01CQECM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) gcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17020 JY8QFUQ01ACCKR No results 17021 JY8QFUQ01AI3Y4 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKDFTYAFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcgtctggattcacGgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17022 JY8QFUQ01C89NK productive Homsap IGHV4-4*07 F 800 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtcttgcaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17023 JY8QFUQ01CLSTV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 825 86.36 190/220 nt 85.0 187/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 42 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); aatgtctggattcacatttagaagctattccatgaattgggGTccggccaggctccagggGAagggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17024 JY8QFUQ01AR4UT productive Homsap IGHV4-61*02 F 929 91.4 202/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARATLSDVDTPLGFDYW in-frame + tctctggtgtctcaatcacgagtggaagtcactactggaattggattcggcagcccgccgggaagggaccggagtggattgggcgtttctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccgtatcagcagacacgtccaagaaccggctctccctgaagctgagatctttgaccgccgcagacacggctgtttattactgtgcgagagcaaccttgtctgacgtggatacacctttgggctttgactactggggccagggaatcttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17025 JY8QFUQ01DOUDD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17026 JY8QFUQ01ANJ7T unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 684 88.95 153/172 nt 88.37 152/172 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.22.11] CARRGDADNYWYFDL## out-of-frame - Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 68 of V-REGION: 48 nucleotides (from position 113 in the user submitted sequence), (do not cause frameshift) ctctggtgactccattggtagtagtgcttactactggggctgggtccgccagcccccagggaaggggctcgaatggatagggaatatttactatggtggcagcacctactacaaccagctcttcctggagctgacctctgtgaccgccgcagacacggctgtgtattactgtgcgagacggggagatgcggataactactggtacttcgatctctgggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17027 JY8QFUQ01CFRYC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17028 JY8QFUQ01AYHDJ unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17029 JY8QFUQ01A8MMQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga 17030 JY8QFUQ01ABPW1 unproductive (see comment) Homsap IGHV3-30*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVGDLTGGSVLL*Q*WFKVL# out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggGggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgtgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 17031 JY8QFUQ01B2DSB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 891 90.32 196/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + ggctggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17032 JY8QFUQ01BTFHC No results 17033 JY8QFUQ01CCV1Y productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1008 94.25 213/226 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [2.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) agcctctggtttcacgttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagtaaagcttacagttccacgacagcatatgctgcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggcgtatctgcacatgaacagtgtgataaccgaagacacggccgtgtattattgtgttagacatgaagggactcccgtaagtgatgtaggaggatacggcatggacgtctggggccaggggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17034 JY8QFUQ01CT8RT No results 17035 JY8QFUQ01AMI0N productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17036 JY8QFUQ01AWFGB No results 17037 JY8QFUQ01CZ4IP productive (see comment) Homsap IGHV1-58*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD3-9*01 F 1 8 8 14 8.8.14 [0.17.38.11] CAAVLAGWGFYYFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tggattcacctttaaaagttctgctatacagtgggtgcgacaggcccgtggacaacgAccttgagtggataggatggaccgccgttggcagcggtaacacagactacgcacagaagttccaggaaagagtcaccattacgagggacatgtccacaagcacagtctacatggagatgatcaacctgggatccgaggacacggccgtgtattactgtgcggcagtcttggccggctggggattctattacttcgatttctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17038 JY8QFUQ01BRETI No results 17039 JY8QFUQ01B9J97 No results 17040 JY8QFUQ01CECYU unproductive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact 17041 JY8QFUQ01BYBMJ No results 17042 JY8QFUQ01B5A9R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17043 JY8QFUQ01BNWCY productive Homsap IGHV3-7*01 F 901 92.38 194/210 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 7 8 14 7.8.14 [X.17.38.11] CVRGRDGVNFGEMDYW in-frame - ttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17044 JY8QFUQ01CUK2I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattctaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17045 JY8QFUQ01DB34V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17046 JY8QFUQ01B7ZOL unproductive Homsap IGHV3-11*01 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CVREVTGVWDWFDS## out-of-frame + in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaAaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgactcctggggccggggcaaccctggtcaccgtctcctcagcatcccctgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggtcttcttcccccaag 17047 JY8QFUQ01BRPGP productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17048 JY8QFUQ01B9RA3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 17049 JY8QFUQ01CUAUN unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt 8 8 X 8.8.X [1.17.38.11] CAKDLFQVSTTYFDY (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcacctTtcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactgggccgggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17050 JY8QFUQ01C4D0M productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 926 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacccttctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 17051 JY8QFUQ01BVVMQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + ctctggattcacctttacctactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17052 JY8QFUQ01B58JB productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1091 99.55 220/221 nt 99.1 219/221 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtagctatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17053 JY8QFUQ01AWGMD productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17054 JY8QFUQ01BCFAZ productive (see comment) Homsap IGHV3-33*04 F (see comment) 711 81.11 176/217 nt 80.65 175/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.16.38.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17055 JY8QFUQ01DR04K unproductive Homsap IGHV3-72*01 F 1011 95.07 212/223 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17056 JY8QFUQ01DJQ8O productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17057 JY8QFUQ01CGTLT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 17058 JY8QFUQ01CT89Y productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 17059 JY8QFUQ01DQWZD unproductive Homsap IGHV3-72*01 F 1083 98.65 220/223 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17060 JY8QFUQ01C2LHC unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17061 JY8QFUQ01B6MMH unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 17062 JY8QFUQ01AZ9UV unknown (see comment) Homsap IGHV3-21*04 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaaggtcttcccgctgagcctcaacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17063 JY8QFUQ01A3X5O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDPQQILAEVNWFDPW in-frame + cctctggattcacctttcgcagctacgccatgagttgggtccgccaggctccaggaagggggctggagtgggtcttctcaatcagtggcagtggtgataaaacaaaatatgcagactccgtgaagggccgattcaccatctccagagacaatgcgaggaatactttttatctgcatatgaacagcctcagagccgcggacacgggcgtctactattgtgcgaaagatcctcagcagatactggcagaagtaaactggttcgacccctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17064 JY8QFUQ01A732T productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARDKGGSYFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtggctccctccatagtgactactGggagctggatccgccagcccccagggaagggactggagtggatcggttacatctcctatagtgggaagaccacatacagcccctccctcaggggtcgactcaccttatcattggacaagtccaggaggcagatctcactgaatctgactgatgtgcacgctccggacacggccgtctattattgtgcgagagataagggagggagttactttgactcctggggccagggaacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17065 JY8QFUQ01AMW1U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.49 182/218 nt 82.11 179/218 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [2.16.38.11] CAKDIWAREWNDMAAFQMW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) gacccccggaatcacTttttcccagctatgtcatgagttgggtcgccaggcccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17066 JY8QFUQ01C636U productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 7 8 22 7.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 2 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17067 JY8QFUQ01AIGU7 productive (see comment) Homsap IGHV3-7*01 F 846 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*01 F 2 8 8 18 8.8.18 [1.16.38.11] CTRDINYSDNGAYYDVFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) cctctggaGtttaccttcagtaatgattggatgatctgggtccgccaggcgccagggaagggactggagtgggtggccacataaggaaagattcaagtatcaaatattatgctgactctgtgaagggccggtttaccgtctccagagacaacaccaagaagtcactgtatctgcaaatgaacaacctgagagccgaggacacggctgtgtactattgtacaagagatattaattactctgataatggtgcatactatgatgtctttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17068 JY8QFUQ01DM63Z productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 913 91.67 198/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame + tcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccca 17069 JY8QFUQ01BFDXK productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame + tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 17070 JY8QFUQ01ASKSP No results 17071 JY8QFUQ01C8DHL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17072 JY8QFUQ01CEN45 productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17073 JY8QFUQ01BH73X productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 14 10.7.14 [1.17.38.11] CARRALDSSGHYIDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tctctggtggctccatgagcagtggtaattactgctggggctggggccgccagccCcccaggaaaggggctggagtggattggaagtatgtgttatggtgggagcacctactacagcttgtCcccccaagggtcgagtcaccatatccatagactcgtcgaagaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagacgcgcattagacagtagtggtcattacattgacatctggggccagggaatcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17074 JY8QFUQ01BB7WV productive Homsap IGHV3-9*01 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame + ctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatggatctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17075 JY8QFUQ01CT4ON productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17076 JY8QFUQ01DBRLD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17077 JY8QFUQ01BVMQQ productive (see comment) Homsap IGHV1-18*01 F 1020 97.66 209/214 nt 97.2 208/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARNIVGAPFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift); tggttacacctttaccagctatggtatcagctgggtgcgacaggGCcccctggacacgggcttgagtggatgggatggatcagcgcttacaatggtaacacaaagtatgcacagaagctccaggacagagtcaccatgaccacagacacatccacgagcacagcctatatggagctgaggagcctgagatctgacgacacggccgtttattactgtgcgaggaatatagtgggagctccttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 17078 JY8QFUQ01BY9RZ productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 844 88.73 189/213 nt 88.26 188/213 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [0.16.38.11] CARSSGGFYYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) tggaggctccttcagcagctttactatcaactgggtgcgacaggcccctgacaagggcttgagtggatgggcgggatcatccccatcttgagtgcagcaaactccacacagaggttccaggtcagagtcacattgaccgcggacgcatccacgggcacagcctacatggagttgaacaggctgacatatgaggacacggccgtttattactgtgcgcggtcgagtggtggtttctactacgctatggacgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17079 JY8QFUQ01AOJXD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 791 85.58 184/215 nt 85.12 183/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); tctctgggggcCaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17080 JY8QFUQ01C57J2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 774 83.87 182/217 nt 83.41 181/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17081 JY8QFUQ01C2SJA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDGMMTFGGVIVPSRFFFDYW in-frame + ctctggattcagctttggtgactatgtcatgagctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtagcggtggaactacatattatgcagactccgtgaagggccggttcaccatttccagagacaactccaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgaaagatggaatgatgacgtttgggggagttatcgtccccagtaggttcttctttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaaagatgggaaccntgggtcgtcgcatgcctggtccagggcttcttccccca 17082 JY8QFUQ01BH9O9 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 913 91.67 198/216 nt 90.28 195/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.16.38.11] CARKGPRRDGSLQQCDMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctgctggattcatcttcagcaaccttgcgatcactgggtccgccagctccaggcaaggGggctggagtgggtggcaattatatcacatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17083 JY8QFUQ01AOSD4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17084 JY8QFUQ01CMEXL No results 17085 JY8QFUQ01CZ9ZV productive Homsap IGHV1-18*01 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame + tggttacccctttaatacctatggtatcacctgggtgcgacaggcccctggacacggccttgagtggatggggtggatcagcgttcacgatggcaacacaaactatgcacagaatctccagggcagagtcaccctgaccacagacacatctacgagcacagtctacatggaactgaggggtctcagatctgacgacacggccgtttattattgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17086 JY8QFUQ01B53SB productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgaggGggcggcttatcgatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 17087 JY8QFUQ01CB1I8 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); tctctggtggcGtccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17088 JY8QFUQ01CUVTZ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 7 8 13 7.8.13 [2.17.38.11] CVSDRELHYQHLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) gcgtctggattcaactcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17089 JY8QFUQ01CHBJS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKRRGGYYIDFDYW in-frame + cctctggattcacctttactagttacagtttcaattgggtccgccaggctccagggaaggggctggagtgggtctcaactatcaatactagtggtagtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacgaggtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaagcggaggggtggttattacatcgactttgactactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17090 JY8QFUQ01CVO3G productive Homsap IGHV1-2*02 F 921 92.52 198/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARISHRGLGYDLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tggatacaccttcaccggctactatatgcactgggtgcgacaggcccctggacaaggccttgaatggatgggctggatcaaccccaacactggtggcacaaattttgcacggcagtttcagggcagggtcgccatgaccagggacacgtccatcaacacagcctacatggacctgaccaggctgcaatctgacgacacggccgtttattactgtgcgagaatttcccatcgggggctagggtacgatttggacgtctggggccacgggaccacagtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 17091 JY8QFUQ01CVKBH No results 17092 JY8QFUQ01DVUMR unproductive Homsap IGHV3-30*01 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [2.17.38.11] CAREWAASHFDH## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); agccgctggattcaccttcagtggctttgcAtttgcactggctccgccaggctccagacaaggggctagagtgggcgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17093 JY8QFUQ01B8QO4 productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-22*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARAPMILVVPKDW in-frame + ctctggattcaccttcagtagcgatgctatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgcatctgcaaatgaacagcctgagagctgaggacacggctgtctattactgtgcgagagccccaatgatactagtggttccgaaggactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17094 JY8QFUQ01AXAHP productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1038 96.41 215/223 nt 95.52 213/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 10 17 7.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) cttctggatcacctttggtgattaGtagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17095 JY8QFUQ01CSN8V No results 17096 JY8QFUQ01BUL6F No results 17097 JY8QFUQ01ARJ9A productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 822 85.65 191/223 nt 84.75 189/223 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 31 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gtctctaatgggctccatcagCcggaagtgtttactactgggcctggatccgccagcccccagAgaaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17098 JY8QFUQ01CZFUL productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt 90.18 202/224 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-11*01 ORF 2 8 10 22 8.10.22 [1.17.38.11] CATDRPYYKNAAGRLWYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); gctctggattcactttcactaacgcgtggatgagttgggtccgccaggctGccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgtttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17099 JY8QFUQ01DIUIX unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.05 199/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSYGF#SVDPW out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccagtagtCttttaccgctggggctggatccgccagtccccagggaagggcctggagtggatAggggaatatcttttatggtgGggaccacctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggtcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 17100 JY8QFUQ01AEB8Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17101 JY8QFUQ01CU8EK productive (see comment) Homsap IGHV3-7*01 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17102 JY8QFUQ01CLVAK No results 17103 JY8QFUQ01CKLTT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 875 88.69 196/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - cagcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17104 JY8QFUQ01BSUY0 No results 17105 JY8QFUQ01AU6Q0 unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17106 JY8QFUQ01DV1NC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame + cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggctcttcccgctgagcctctgcagcacccagccagcatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccagg 17107 JY8QFUQ01AE063 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 17108 JY8QFUQ01C73QL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17109 JY8QFUQ01C1KKC unknown (see comment) Homsap IGHV3-48*01 F (see comment) 590 74.31 162/218 nt 72.94 159/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (74,31% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttatagcatgaactggGgtccgccaggctccagggaaGggggctggagtggAttttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagagcacctctgggggacacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17110 JY8QFUQ01DRCDC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaAatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17111 JY8QFUQ01CJ6A1 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17112 JY8QFUQ01CN2NY No results 17113 JY8QFUQ01CBQ54 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17114 JY8QFUQ01AL5IC No results 17115 JY8QFUQ01CB6XD unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREGGGQFVG##YFDYW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtgcttacatatactacgcagactcaatggagggccgattcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgcgagaggggggcgggcagttcgtcggaagactactttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17116 JY8QFUQ01CO47U productive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) ctctggattacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17117 JY8QFUQ01BZT3E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 593 75.35 162/215 nt 74.88 161/215 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (75,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17118 JY8QFUQ01BO6OR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [0.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17119 JY8QFUQ01DTZUH unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccaGgggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaGggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17120 JY8QFUQ01BMLSJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 165 75.0 45/60 nt Homsap IGHD6-19*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARQYTSGEMDGW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctagattcaggttcagtagttataccatgacctgggtccgccaggctccagggaagggactggagtgggtctcatcgatcactagtgggagtagtcatatacactatgcagactcagtgaaaggccgattcaccatctccagagacaacggcaaaaactcactttatctgcaaatggacagcctgagagccgaagacacggctctatattactgtgcgagacaatacaccagtggcgagatggacggctggggccaggggaccacggtcttcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagcagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17121 JY8QFUQ01CTR9B unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctacagcagccatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17122 JY8QFUQ01BB4E3 No results 17123 JY8QFUQ01A2MYW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1003 96.3 208/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17124 JY8QFUQ01CAKEH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 89.9 187/208 nt 88.94 185/208 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 6 8 17 6.8.17 [X.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 47 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cacctttaatagctatgccatggcctgggtccgccaggctccagggGAagggggctggagtGgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact 17125 JY8QFUQ01B0Q2W No results 17126 JY8QFUQ01BRIGU unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17127 JY8QFUQ01DQ8N5 productive (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttCggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17128 JY8QFUQ01DASZH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagtacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17129 JY8QFUQ01BRS32 No results 17130 JY8QFUQ01AUT33 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 95 67.39 31/46 nt Homsap IGHD7-27*01 F 1 8 7 6 8.7.6 [1.17.38.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) tccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccGgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17131 JY8QFUQ01AH7BA unproductive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 930 92.99 199/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKGSFDSSGRPEAFDI## out-of-frame + Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggaggcaccttcagtagatatgctttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtccctctctttggttccataaagtacgcacagaagtaccagggcagagccacgattaccgcggacgaatccacgagcacagtctacatggagctgagcagcctgagatctgacgacacggccatgtattactgtgcgaagggttcctttgatagtagtggtcgccctgaggcttttgatatctggggccaagggtacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17132 JY8QFUQ01ANLMX productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 962 92.41 207/224 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD1-26*01 F 3 8 10 14 8.10.14 [1.17.38.11] CTRDLSGSYSGAFDVW in-frame + gatctggattcacctttggtgactttgctatgagctggtttcgccaggctccagggaaggggctggagtggctaggtttcattagaagcaaaatttatggtgggacaccagaatacgccgcgtctgtgaaaggcagatgtcccatctcaagagatgattccaaaaacatcgcctatctgcaaataaacggcctgaaaaccgaggacacagccatgtatttctgtaccagagatctcagtgggagctactccggtgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17133 JY8QFUQ01AQJ3F unknown (see comment) Homsap IGHV3-74*03 F 133 55.73 73/131 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 17134 JY8QFUQ01BMZNK productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-16*02 F 3 8 7 9 8.7.9 [4.17.38.11] CARGDPIFMIV in-frame + cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccattttcatgatagtgttaaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17135 JY8QFUQ01C90SO unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVRWKMDRSGVSAAATDVFGMDV## out-of-frame - gcctcgggattcaccttcagtggctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatggtaagaataaatacatctactatgcagactcactgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaccaacctgagagccgaggacacggctctatattactgtgtgagatggaagatggataggagtggtgtaagtgcagcggcaacagacgttttcggtatggacgtctgggggccaagggaccacagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17136 JY8QFUQ01ANOOW productive Homsap IGHV4-39*07 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 9 7 15 9.7.15 [1.17.38.11] CARAVLDNAWPIYYDFW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01ANOOW ; 10 AA in Homsap_IGHV4-39*07), and low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccatcaccacttggcattactggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17137 JY8QFUQ01B8J97 No results 17138 JY8QFUQ01AVKTX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [0.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17139 JY8QFUQ01DXGB2 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-6*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRSYSRTSEFDYW in-frame + cgtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaaatttatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctgagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagtttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17140 JY8QFUQ01DLVUV unproductive (see comment) Homsap IGHV4-31*06 F 996 94.98 208/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARVIIDDSGGNY#FDYW out-of-frame - stop codons ctctggtgcctccatcagcagtggtatttactactggagctggatccgccagcacccaggggagggcctggagtggattgggtacatctctgacagtgggagcacctactacaacccgtccctcaagagtcggtttaccgtatcagtggacacgtctaagaaccagttctctttgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagtaataatagatgactccggtggtaactacctttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgcccctgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17141 JY8QFUQ01C3DN4 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctgggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17142 JY8QFUQ01CJEDT productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17143 JY8QFUQ01CODA3 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17144 JY8QFUQ01CZ6MM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaactttggtgactttgtcatgacttgggtccgccaggctccagggaagggactagaatgggtctcatctattagtggtactggtactctcacttactacggaaactccgtgaagggccacttcaccatctccagagacaattccgacaacacagtctatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17145 JY8QFUQ01CCHJL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17146 JY8QFUQ01BCRD7 No results 17147 JY8QFUQ01CXLQ9 unproductive Homsap IGHV1-3*01 F 621 95.59 130/136 nt 94.85 129/136 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*02 F 3 8 X X 8.X.X [0.3.34.11] CTRGRGAGNFPPNPI#FDPW out-of-frame + in FR2-IMGT, from codon 42 of V-REGION: 78 nucleotides (from position 35 in the user submitted sequence), (do not cause frameshift) tggatataccttcactagttatgctatacattggaacttccagggcagagtcaccattaccagggacacatccgcgagcacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtatttctgtacgagaggccggggggcagggaacttccctcccaaccctattgttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaatgatgggaacgtggtcgtcgcatgtctggtccagggcttcttcccccga 17148 JY8QFUQ01DHGWP unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 661 78.24 169/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt 8 8 X 8.8.X [1.17.38.6] RTGD (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION identity (78,24% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17149 JY8QFUQ01AFGYG productive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17150 JY8QFUQ01AWDVJ productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattattcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17151 JY8QFUQ01DP1K8 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 9 8.7.9 [4.17.38.11] CARGDPSFHDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggaccccagttttcatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17152 JY8QFUQ01B7OB3 No results 17153 JY8QFUQ01ANMUX No results 17154 JY8QFUQ01DCZPW productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17155 JY8QFUQ01AU8W0 No results 17156 JY8QFUQ01DHW2H productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + ttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17157 JY8QFUQ01AZEES productive Homsap IGHV3-72*01 F 957 92.38 206/223 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.17.38.11] CARLHYSGGWYGLDVW in-frame + ctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtgggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagatgactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17158 JY8QFUQ01A59ZU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17159 JY8QFUQ01AM0UE productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 17160 JY8QFUQ01CP0O1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17161 JY8QFUQ01ALADF unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1022 96.79 211/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame + stop codons cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggatggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaactgtgtcgtcgcatgcctggtccagggcttcttccccca 17162 JY8QFUQ01CWY4Y unproductive Homsap IGHV4-61*03 F 876 88.34 197/223 nt 87.89 196/223 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 3 10 7 X 10.7.X [2.17.38.11] CTRHPKSNVEGDS## out-of-frame - in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift); gtcccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagACcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagcccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17163 JY8QFUQ01APH2J productive Homsap IGHV1-18*01 F 867 89.72 192/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-8*02 F 1 8 8 23 8.8.23 [0.17.38.11] CVRDIGWTSYKGKWSCTVCDAFDIW in-frame + tggttacacttttagcaattatggtgtcagctgggtgcgacaggcccctggacaaggatttgagtggatgggatggattagcggctccaatggtaaaacagagtatgcacagaagttccaggacagggtcaccatgaccacagacacattcacgagcacagcctatatggagatgaggagcctgagatctgacgacacggccatgtattattgtgtgagagatatcgggtggacctcctataaagggaagtggtcttgtacggtatgtgacgcttttgacatctggggccaagggacaatggtctccgtctcttcagcatcccgaccagccccaaggtcttcccggctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccgagggcttcttcccccc 17164 JY8QFUQ01CZCD5 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggctttttccccca 17165 JY8QFUQ01C2O4Z productive (see comment) Homsap IGHV4-61*02 F 1028 96.38 213/221 nt 95.93 212/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARAPSYTNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 116 to 117 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttactactggagttggattcggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaaACcccctccctcaagagtcgagtcaccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattattgtgcgagagctccctcttataccaactcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctccttccccca 17166 JY8QFUQ01CHHJB productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.37.11] CVRDLNWSFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 74 of V-REGION: 1 nucleotides (from position 127 in the user submitted sequence), (cause frameshift) gcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaaggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17167 JY8QFUQ01CIDRZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 775 84.02 184/219 nt 82.65 181/219 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [2.17.38.11] CARDSALFGYARYDAMDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'TG' (2 nucleotides at position 28 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); gcctctggatccagtttcagtggttttTGggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggGggccggttcaccatTttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17168 JY8QFUQ01BY57B No results 17169 JY8QFUQ01DIP27 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattcacatttcgaagttattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcggctgtaagtggtggtggcggcgccacaacctacgcggactccgtgaagggccggttcaccatctccagagacaatacacagaagatggtgttcctagaaatgagcagcctgagagtcgaagacacagccttatattattgtgcgcgagatgacgggggacacatgactttagatgtctggggccaggggacaatggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcgttcttccccca 17170 JY8QFUQ01DSPF8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 81.74 179/219 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [2.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcctctggattCcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggGggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17171 JY8QFUQ01BHLSA No results 17172 JY8QFUQ01A9DV9 No results 17173 JY8QFUQ01BUZY7 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17174 JY8QFUQ01AKWWD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17175 JY8QFUQ01CWEVR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCGNGACHVADYW in-frame + ctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17176 JY8QFUQ01B7WOD No results 17177 JY8QFUQ01AGCMW productive (see comment) Homsap IGHV4-61*02 F 969 93.64 206/220 nt 92.27 203/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 2 10 7 19 10.7.19 [1.17.37.11] CARVVRCTTTGCSRVGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 216 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtgatgattactactggagctggatccggcagcccgccgggaagggactggagtggattGgggcgtatctcttccagtgggaacaccaactacaaCcccctccctcaggagtcgagtcaacatttcactagacacgtccaagacccagttctccctggagctgacctctgtgagcgccgcagacacggccgtgtatactgtgcgagggtcgttcgttgtactacgaccggctgctcaagggtaggatggttcgacccctggggccagggaaccctggtaaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17178 JY8QFUQ01B5VSY productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CC' (2 nucleotides at position 79 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); tctctggtggctGccatcatcagagacagtgcctactggggctggatccgccagccccagggaaaggggctggagtggCCtttgggagcatctattatagtgGggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17179 JY8QFUQ01CQQA9 unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ5*01 F 111 68.63 35/51 nt 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccaggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17180 JY8QFUQ01BWEUM unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 770 83.94 183/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRLNW*LHIRR#FDLW out-of-frame + stop codons Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctaaatttgacttcagtgactatggcatgaactgggtccgccaggttccagggaaggggctggagtgggtctcctacataagtcgtctgagtcgccaaatatatgtcgctgacccagtgaagggccgattcaacatctccagagacaacgccaagaattcactgtatctgcaaatgaacaacttgcgggtcgaagacacggctgtgtatttttgtgccaaagatcgcctgaactggtgactacacattcggcgcattttgatctgtggggcccagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacacgcggccctgggctgcctggtcaaggactacttgccccgaaccggctgacggtgtcgtggaactca 17181 JY8QFUQ01AXVM2 unproductive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [1.17.38.11] CVKK*PVLGHNR##YFDYW out-of-frame + stop codons cctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17182 JY8QFUQ01A151U productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgGggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17183 JY8QFUQ01BWHJI productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17184 JY8QFUQ01CQT8B productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17185 JY8QFUQ01CY1LD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [1.17.38.11] CANASPRITGTYFYYYGMDV# out-of-frame + Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctgggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaaactca 17186 JY8QFUQ01B5VXZ No results 17187 JY8QFUQ01CIKB3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17188 JY8QFUQ01CB1U7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CAKTQPFGTTWYGATDAW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctgggtttacctttagcaactttgccatggcttgggtccgccaggctccaagaaaggggctggagtgggtctcagctattgctcgtggcggtgacacacactaccgagactccgtgaagggccgattcaccatctccagagacaattctaagaacacactgattctgcagatgagcagcctaagagccgaggacacggccttatattactgtgcaaagacgcagccgtttggcaccacctggtacggtgctacggatgcgtggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17189 JY8QFUQ01AOPK3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1026 97.24 211/217 nt 96.77 210/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVRGGYYRHDAFHIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaAaggggctggtgtgggtctcacgtattaatagtgatgagagtaccacaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtttctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgtacgtggtggttattaccgtcatgatgcttttcatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17190 JY8QFUQ01AU7SF No results 17191 JY8QFUQ01B0XOZ productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17192 JY8QFUQ01DIHPZ No results 17193 JY8QFUQ01CAMSC unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ3*01 F (see comment) 124 72.0 36/50 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPSQVGYYLD#VG out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17194 JY8QFUQ01CWRKR No results 17195 JY8QFUQ01CWWMH unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 930 92.56 199/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons tctgattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggantgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17196 JY8QFUQ01BF6UR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARVRLDIVATIVDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatagtgatgggagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagttcgcctggatatagtggctacgattgttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc 17197 JY8QFUQ01CGQO6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17198 JY8QFUQ01AQGGO productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctagtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17199 JY8QFUQ01BNGO7 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARDRSNYYSDYW in-frame + gtctggattcattttcagtaattatggcatgcgctgggcccgccaggctccaggcaaggggctggagtgggtggcatttatatggtatgacggaagaaataaatactattcagactccgtgaagggccgattcaccatctccagagacaattccgaggacacgctgtatctggaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagataggagtaattactactctgactactggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17200 JY8QFUQ01ASJTT unproductive Homsap IGHV3-30*01 F 927 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDELPWDTIEYYFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcaatattttttctangcactgggtccgccaggctccaggcaagggactagagtgggtgtcacttgtttcatatgatggatctaagaaaaagtacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatgagctgccttgggacacaattgaatattattttgactattgggggccagggaagcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 17201 JY8QFUQ01DTGSH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 744 82.27 181/220 nt 81.36 179/220 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] TCVRDSDSSGYARYDSMDV## out-of-frame - Low V-REGION identity (82,27% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); agcctctggattcGaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcCggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggatttatacttacttgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctgggggccaagggaccgcggtcaccgtctcatcagccctccacccaaggggccccatcggtcttacccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca 17202 JY8QFUQ01COPN0 productive (see comment) Homsap IGHV3-9*01 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tctggattcacctttaatcaGttatggcatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaggtattagttggaatagcggaagtagagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17203 JY8QFUQ01CWXQD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.16.38.11] CAKRYSGSFYAS##WFHPW out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggaggggcgtggagtggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17204 JY8QFUQ01CY9EY productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt 94.57 209/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtaatagttTtctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17205 JY8QFUQ01DWHJ1 No results 17206 JY8QFUQ01DOPW2 unknown (see comment) Homsap IGHV2-5*03 F (see comment) 204 56.25 108/192 nt 10 7 X 10.7.X [9.17.26.X] null - No rearrangement found stop codons Low V-REGION identity (56,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccagggacaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17207 JY8QFUQ01C9VHM unknown (see comment) Homsap IGHV1-8*01 F, or Homsap IGHV1-8*02 F 274 93.55 58/62 nt 8 X X 8.X.X [0.12.X.X] null - No rearrangement found tggatataccttcaccagatatgatatcaattgggtgcgacaggccactggacaagggcttc 17208 JY8QFUQ01AGHGA unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 17209 JY8QFUQ01AVPY3 productive Homsap IGHV3-48*03 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDKSAAWYAYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttctcccatgaactgggtccgccaggctccagggaggggactggagtgggtctcatacattagcagtagtggaactaccacatattacgcagactctgtgcagggccgattcaccgtctccagagacaatgccaagaacctactgtatctgcaaatgaacagcctgagagccgaggacacggctttttattattgtgcgaaagataagagcgctgcctggtacgcctactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17210 JY8QFUQ01B6T1P No results 17211 JY8QFUQ01BTN0C No results 17212 JY8QFUQ01CPROL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 467 89.57 103/115 nt 88.7 102/115 nt 8 7 X 8.7.X [1.17.5.X] null + No rearrangement found in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) tctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccg 17213 JY8QFUQ01CRILY No results 17214 JY8QFUQ01CD483 productive Homsap IGHV3-11*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-7*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARGKGKGGTTYYGMDVW in-frame - cctctggattcactttcagtgactactacatgaattgggtccgccaggctccagggaagggcctggagtggctttcatacattactgcaagtggtgccatcatacactatgcagactctgtgaagggccgattcatcatctccagggacaacgccaagaactcactgtctctgcagatgaacagcctgagagccgacgacacggccgtctattattgtgctcgggggaagggcaagggtggaactacctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17215 JY8QFUQ01ATKO3 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPRSVSRYSLFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatttttgtgcgagagatcctcgttccgtgagcaggtactctttatttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17216 JY8QFUQ01B095W unknown (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-4*08 F or Homsap IGHV4-59*01 F or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F 641 85.14 149/175 nt 8 7 X 8.7.X [1.17.24.X] null + No rearrangement found tctctggtgactccatcagttctgcatacagtaactggatccggcagcccccagggaagggactggagtggattgggtgtattcatcccagtgggactactcattacaacccctccctcaagagtcgagtcgccatgtcaacagacacgtcgaagaaccagttctccctgagact 17217 JY8QFUQ01CV8Z5 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 971 94.88 204/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.16.38.11] CARGEMTAEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaagggctggagtggattgggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17218 JY8QFUQ01BEIT8 No results 17219 JY8QFUQ01BM6ET productive (see comment) Homsap IGHV4-61*02 F 866 88.24 195/221 nt 86.88 192/221 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*01 F 2 10 7 19 10.7.19 [1.17.38.11] CAREAPKTAGDSYGSLAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 217 to 217 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagtagtggCtttttactactggagctggacccggcagcccgccgggCaagggactggagtggattgggcgtgtccatagcggtggtagttccgactacaacccctccctcacgggtcgagtcaccatcttagtggactcctccaagaatcagttctccctgaggctgacctctgtgacggccgcagacgcggccgtgtaAtttctgtgcgagagaagcgcccaagacagcaggtgattcctacggctctctcgctatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17220 JY8QFUQ01BCZ7N No results 17221 JY8QFUQ01C7436 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATSRGSANWYPFDHW in-frame - ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17222 JY8QFUQ01ALJ94 productive Homsap IGHV3-7*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [0.17.38.11] CAGGRGWLIDYW in-frame + tggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17223 JY8QFUQ01CRELC productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + cttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 17224 JY8QFUQ01CDWQU productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 677 80.19 170/212 nt 79.25 168/212 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [0.17.38.11] CVRDAETTVSGVAGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctggattcagctttagcGatttttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17225 JY8QFUQ01CXQQC productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 782 85.12 183/215 nt 84.19 181/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttGctttcttacagtgGggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17226 JY8QFUQ01C3SES productive (see comment) Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 871 90.14 192/213 nt 89.67 191/213 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [1.17.38.11] CARDGRGGDLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctgggttctccgtcagtttcaactacatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17227 JY8QFUQ01A4SKX productive (see comment) Homsap IGHV1-2*02 F 858 89.25 191/214 nt 88.32 189/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*01 F 3 8 8 19 8.8.19 [0.17.38.11] CARDEANIEVVMTSNYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'C' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tggatacaccttcaccggccactatctacactgggtgcgacaggcccctggacaaggCacttgagtggatgggatgggtaaacatcaagagtggtggAcacaaattatccacagaagtttcacggcaggatcaccatgaccagggacacgtccatcaacacagccttcttagaagtgaccagcctgagatctgacgacacggccgtttattactgtgcgagagacgaggccaatattgaagtagtaatgacctctaattattattttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcancgcctgcctgggtccagggcttcttccccca 17228 JY8QFUQ01ABHA8 No results 17229 JY8QFUQ01DJKQL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17230 JY8QFUQ01CDOKK productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1012 96.76 209/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [2.17.38.11] CARGGGYYFVAIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'AG' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaaAGtggggagcaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17231 JY8QFUQ01DER2Y No results 17232 JY8QFUQ01CB3MM productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame + tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17233 JY8QFUQ01AGXB8 productive Homsap IGHV3-21*04 F 963 94.01 204/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcgacttcagtagatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttgatagtaattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcgctgtttctgcaaatgaacagcctgagagccgatgacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17234 JY8QFUQ01BNG1R productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagccCcccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 17235 JY8QFUQ01CDU9L No results 17236 JY8QFUQ01B0NLO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17237 JY8QFUQ01CXJM1 No results 17238 JY8QFUQ01A3934 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - ctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgataagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17239 JY8QFUQ01DGW2D unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17240 JY8QFUQ01ALI2N unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 709 81.69 174/213 nt 80.75 172/213 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDWGGSFDRYYFDY## out-of-frame + Low V-REGION identity (81,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'AG' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactgggAGgtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtCccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccaggggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttnttcccccca 17241 JY8QFUQ01BGDI2 No results 17242 JY8QFUQ01DAQ0I productive Homsap IGHV3-48*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKDRGGSAYPIFDYW in-frame - gcctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17243 JY8QFUQ01A9XAG unproductive Homsap IGHV3-7*01 F 967 94.44 204/216 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFYSTGY## out-of-frame + tctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17244 JY8QFUQ01ATZ5Y productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactcag 17245 JY8QFUQ01B2M7V productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17246 JY8QFUQ01AJ2JB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttGatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17247 JY8QFUQ01AT6Y6 productive Homsap IGHV3-9*01 F (see comment) 789 84.55 186/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release agcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17248 JY8QFUQ01AR7H6 productive (see comment) Homsap IGHV3-7*01 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.16.38.11] CAKARIYFYGSGSYSLFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctccggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17249 JY8QFUQ01DNNOD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17250 JY8QFUQ01C9C4P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17251 JY8QFUQ01DAV2B productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17252 JY8QFUQ01BLY7O productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 35 to 36 in the user submitted sequence), (cause frameshift); tccggattcagtttcagtacttataacatgaattTGggtcccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17253 JY8QFUQ01A2D3K No results 17254 JY8QFUQ01C6ESZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17255 JY8QFUQ01BS8R3 No results 17256 JY8QFUQ01AX36U productive Homsap IGHV3-66*02 F 926 92.56 199/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CSTPTYCRGGSCSQIFDYW in-frame + cctctggattcaccgtcagtaactaccacatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagatttttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17257 JY8QFUQ01CQUPT productive (see comment) Homsap IGHV3-48*02 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*01 F 3 8 8 11 8.8.11 [2.17.38.11] CAKVGKLYFFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGgtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagcacgaccataggctacgcagactctgtgaggggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggatagcctgagagacgaggacacggctgtgtatttttgtgccaaagtgggaaagttgtatttctttgaatactggggccggggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17258 JY8QFUQ01BVITE productive (see comment) Homsap IGHV3-66*02 F, or Homsap IGHV3-66*03 F 878 89.45 195/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-25*01 F 1 8 7 11 8.7.11 [2.17.38.11] CARDGRGGDLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); cagtgtctgggttctccgtcagGtttcaactacatgagctgggtccgccaggctccagggaaGggggctggagtGgggtctcagttatctatgccgatggaagtacattctatgcagactccgtgaagggccgattcatcatctccagagacaattcaaagaacacgctcaatcttcaaatgaatagtttgagagttgacgacacggctgtgtattactgtgcgagagatgggcgcggcggtgaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17259 JY8QFUQ01AOBLF No results 17260 JY8QFUQ01CV2CU productive (see comment) Homsap IGHV3-23*03 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagaagctatgccatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 17261 JY8QFUQ01ALXV8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattcaccttcagtcgctatagtatgaattgggtccgccaggctccagggaaggggctggagtggctcgcatacatcagtaggagtactaatgacatatactactcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttgtggggcctagggacagtggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17262 JY8QFUQ01C2K0Q productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARTTSSSGWYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggaggctccattagtaattactacCtggagttggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaatcagttcttcctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgaggactacttctagtagtggctggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17263 JY8QFUQ01BRA99 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [1.17.38.11] CANASPV*LE#YFYYYGMDVW out-of-frame - stop codons tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17264 JY8QFUQ01CWO1D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame + ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17265 JY8QFUQ01DDTC0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1110 100.0 223/223 nt 99.1 221/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [2.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tgtctctggtCggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17266 JY8QFUQ01DBEAF productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 9 8.8.9 [1.17.38.11] CATRSQAMADW in-frame + ttcaggattcagcttcagttcctattggatgagttgggtccgccaggccccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagaaaaactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcgttgtttttggagatgagcagcctgagagccgaggacacggctgtctattactgtgccacgaggagtcaagccatggctgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccc 17267 JY8QFUQ01C1SB2 No results 17268 JY8QFUQ01AS6I7 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17269 JY8QFUQ01BK2LJ No results 17270 JY8QFUQ01CULNG No results 17271 JY8QFUQ01BFGR4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ6*01 F (see comment) 117 68.52 37/54 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSG## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggccaggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17272 JY8QFUQ01AS7OK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame + cctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17273 JY8QFUQ01BXGWV No results 17274 JY8QFUQ01CE17X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17275 JY8QFUQ01B62EW No results 17276 JY8QFUQ01CW34D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame + ctctggtttcacctttagtagtcatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 17277 JY8QFUQ01CN0DI productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 17278 JY8QFUQ01B7JCR productive (see comment) Homsap IGHV3-9*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaactttaataattatgccatgcactGgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17279 JY8QFUQ01C1V49 productive Homsap IGHV4-61*02 F 816 85.45 188/220 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [1.17.38.11] CARGMATIKTVRFDPW in-frame + ctctggtggctccatcaggagcggaattaattcctggacatggatccggcagcccgccgggaagggactggagtgggttgggcgtatttacgtcaatggagacaccaactacaacccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttttccctgcagttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggctacaataaagacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 17280 JY8QFUQ01BU0AH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17281 JY8QFUQ01A1MJG productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 7 17 8.7.17 [1.17.38.11] CARVVMATVYTGSYYFDDW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); gtatggtgggtccttcagtgataactcctggacctggatccgccagcCccccagggaaggggctggagtggattggagagatcaatcatagtggaaacaccaactacaacccgtccctcaggagtcgagtaatcatgtcaatagacacgtccatgaaccaattctccctgaagctgacttctgtgaccgccgcggacacggctgtgtattattgtgcgagagtcgtgatggctacagtttatactgggtcctactactttgacgactggggccagggaaccctggtctccgtcttctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtcagggcttcttccc 17282 JY8QFUQ01BRQMG productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 970 91.34 211/231 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 10 9 19 10.9.19 [3.17.38.11] CARASRRDRQSDRNYYELDFW in-frame - catctacccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcaattgaactccgttagtcccgaggacacggctgtgtattactgtgcaagagcttccagacgcgatcgtcagtctgatcggaactactatgagctggacttctggggccagggaatcttggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17283 JY8QFUQ01AIAUG productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17284 JY8QFUQ01CWH7Q productive (see comment) Homsap IGHV4-61*02 F (see comment) 779 84.4 184/218 nt 83.03 181/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'CTT' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) tctctggtgcctccatcactagtggtaCTTactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactgggagcacctattacaaTcccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17285 JY8QFUQ01CYV4I unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 99 59.72 43/72 nt 7 X X 7.X.X [X.17.X.X] null - No rearrangement found ttcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17286 JY8QFUQ01CEQHK productive (see comment) Homsap IGHV3-7*01 F 1044 98.16 213/217 nt 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaaggaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17287 JY8QFUQ01DO8DA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 925 92.96 198/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [X.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'CC' (2 nucleotides at position 85 to 86 in the user submitted sequence), (cause frameshift); ggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaagGgggctggtgtgggtgtcacgtagtaataCCggggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17288 JY8QFUQ01CO3DK productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgataatttctactggggctggatctgccagcccccagggaagggactgcagtggattgGggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17289 JY8QFUQ01BY42Y unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 406 82.35 98/119 nt 8 8 X 8.8.X [1.17.5.X] null + No rearrangement found Low V-REGION identity (82,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctg 17290 JY8QFUQ01CVFZZ productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17291 JY8QFUQ01CH5XG productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17292 JY8QFUQ01AU604 productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame + gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 17293 JY8QFUQ01B4JEZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'CGC' (3 nucleotides at position 36 to 38 in the user submitted sequence), (do not cause frameshift); cctctggattcacctttagcacctatgccatgagaCGCtgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17294 JY8QFUQ01AQDHE productive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17295 JY8QFUQ01BRIHD productive Homsap IGHV3-7*01 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17296 JY8QFUQ01A72N8 productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame + Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 17297 JY8QFUQ01A2PAK unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 17298 JY8QFUQ01BPHS4 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CXKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtncgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17299 JY8QFUQ01CYQ3S No results 17300 JY8QFUQ01A4YVV productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAARIDSGHYWNAFDIW in-frame + tggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacttgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17301 JY8QFUQ01AWHX3 No results 17302 JY8QFUQ01CRBFS productive (see comment) Homsap IGHV4-59*03 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 89 to 94 in the user submitted sequence), (do not cause frameshift); ctctggtgtctccatcagtagtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17303 JY8QFUQ01B8C40 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17304 JY8QFUQ01AEURC No results 17305 JY8QFUQ01C70N2 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 657 77.88 169/217 nt 76.96 167/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,88% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcgccacttatcattggtggAacttgggtccgccagaccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaatccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17306 JY8QFUQ01ARHX6 productive Homsap IGHV3-9*01 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame + cctctagattcacctttaatggttactggatgagttgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17307 JY8QFUQ01BXMGR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17308 JY8QFUQ01AGDPV productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17309 JY8QFUQ01ASWON productive Homsap IGHV4-39*02 F 866 88.24 195/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 17 10.7.17 [1.17.38.11] CARQMGYSGSGLSVWFDPW in-frame + tctctggaggctccatcaacactaatcgttactactgggtctggtttcgccagcccccggggaaggggctggagtggattgggactatttattatactgggatcaccaactacaatccattcttcaagagtcgagtcaccatgtccgtagacacgtccagccaccacttctccctgaggttgagctctgtgaccgccgcagacacggctgtctactactgtgcgagacaaatgggatactctggttcggggctcagtgtgtggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17310 JY8QFUQ01AX55X productive (see comment) Homsap IGHV3-49*04 F (see comment) 804 84.75 189/223 nt 83.86 187/223 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD3-3*01 F 2 8 9 16 8.9.16 [1.17.38.11] CARDRDYHDSWPDSFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 88 in the user submitted sequence), (cause frameshift) cttctggattcaccttaggtgattattgtctaatgtgggtccgacagtttccaGgggaagcgactggagtgggtaggcttcattagaatgcactttttggtgggaccacagaatacgccgcgtctgtgaaaggaagattcaccatctcaagagatgactccgagggcatcgcccacctagagatgaacagtctcaacaccgaggacacagccgtgtattattgtgctagagaccgcgattatcacgatagttggcccgattcttttgatgtctggggcccagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17311 JY8QFUQ01BK51A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.16.38.11] CAKGIVGASMQADWFHPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggaggggcgtggagtggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17312 JY8QFUQ01BHE4G productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARCKSAGLVDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcagcattagcgactatgccatggcctgggtccgccaggctccagggaaggggccggagtgggtctcaagtgttactaatggttttggcacatactacgcagactctgtgaagggccggttcaccgcctccagagacaattccaagaacgcattgttcttggaaatgaacatcctcagagccgaggacacggccgtatattattgtgcgaggtgtaagtcggccggtttggtggactggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17313 JY8QFUQ01DMKXA productive (see comment) Homsap IGHV1-3*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [0.16.38.11] CATGLCGTACYLLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacaccttcactaactatcccatacattgggtgcgccaggccccggacaaaggcttgagtggatgggattgatcagcgctggcaatgataacacaagattttcacagaagttccagggcagagtcaccattaccagggacacagccgcgaacacagcctacatggagttgagcagcctgacatctgaagacacggctgtgtactactgtgcgacaggcctctgcggtactgcctgctatctgcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17314 JY8QFUQ01B06KG unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARLGATR##DYW out-of-frame + stop codons ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttggggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctcccaccaacgggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctcggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17315 JY8QFUQ01BJOAR productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARGTSVDPGIDHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaattattggatgcactgggtccgccaggtttcagggaggggcgtggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17316 JY8QFUQ01BHYT1 No results 17317 JY8QFUQ01A33HU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17318 JY8QFUQ01AZMST unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 987 94.55 208/220 nt 94.09 207/220 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.16.38.11] CARRGRCG*#YWYFDLW out-of-frame - stop codons in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctagtgactccatcagcagtactaattactactggggctggatccgccagccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17319 JY8QFUQ01BLS2S productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 945 93.09 202/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'CC' (2 nucleotides at position 88 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 138 to 138 in the user submitted sequence), (cause frameshift); ctctggattGcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCCggggggggactgacacagcctacgcggactccgtgaagggccgattcaAccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 17320 JY8QFUQ01AU7VX productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17321 JY8QFUQ01DBBUF unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 917 92.09 198/215 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARRGRCG*#YWYFDLW out-of-frame + stop codons tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacgggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 17322 JY8QFUQ01BIF8K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17323 JY8QFUQ01BI0YI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17324 JY8QFUQ01AAXLX No results 17325 JY8QFUQ01ALDS2 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDA#FDLW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcattttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17326 JY8QFUQ01AZBA5 No results 17327 JY8QFUQ01DQVX4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17328 JY8QFUQ01BQYYZ No results 17329 JY8QFUQ01A1V61 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRWASNGWSW#YFDYW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgagcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17330 JY8QFUQ01AVTO1 unproductive (see comment) Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons tctggagttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17331 JY8QFUQ01DJ1Y1 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame - gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17332 JY8QFUQ01C9LX0 productive Homsap IGHV3-30*01 F 883 89.5 196/219 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [2.17.38.11] CACGHMRDGYDVW in-frame - gcctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17333 JY8QFUQ01C5F9U No results 17334 JY8QFUQ01B08DF productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame + tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17335 JY8QFUQ01DMHMQ productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 743 82.49 179/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 9 7 15 9.7.15 [1.17.37.11] CARVWVAGSRDENFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) ctcgggtggttccatgacgagtactaattctactggagttgggtccgccaacgctcagggaagggcctagagtggcttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgtttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17336 JY8QFUQ01CKNQR productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17337 JY8QFUQ01BPX0B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca 17338 JY8QFUQ01BRXZI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 922 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcacctttagccCactttgccgngacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17339 JY8QFUQ01CJGDZ No results 17340 JY8QFUQ01A0JNN No results 17341 JY8QFUQ01AWIXW productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc 17342 JY8QFUQ01A5UU6 unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 88.69 196/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgGggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttcggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 17343 JY8QFUQ01CA8IW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggaGttcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17344 JY8QFUQ01DH7MJ unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactca 17345 JY8QFUQ01CKLBU productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17346 JY8QFUQ01ADEKS No results 17347 JY8QFUQ01CGSFP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKYVEGVVIYGGLL##SYAMDVW out-of-frame - in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaacAtccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggagggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17348 JY8QFUQ01BOB7M No results 17349 JY8QFUQ01A33TY productive (see comment) Homsap IGHV4-61*02 F 957 92.38 206/223 nt 91.93 205/223 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [2.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); gtcgtctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaGcccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcagccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17350 JY8QFUQ01ASDDF productive Homsap IGHV4-61*02 F 961 92.79 206/222 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [2.17.38.11] CATVARRGAFDIW in-frame - tcgtctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17351 JY8QFUQ01CLDVV productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 900 90.32 196/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame - ctctggattcaccttcagaagttctgcccttcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtaacatcatatgatggaggtgataaatcctacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctatatctgcgaatgactaacctgagacctgaggacacggctgtctattactgcgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17352 JY8QFUQ01AX1CJ productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17353 JY8QFUQ01DIDF7 No results 17354 JY8QFUQ01C7A43 No results 17355 JY8QFUQ01A83TT productive (see comment) Homsap IGHV3-11*01 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-7*01 F 1 8 8 15 8.8.15 [2.17.38.11] CVRESRSWTGSTLPAYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtgactattacatgagttggtaccgccaggctccaggtcaggggctggagtggctttcatatataagtcaaactggCgaaaaccacatacttcgcagactctgtgaagggccgattcaccatctccagggacaatgccaagacatcagtgtttctgcaaatgaacagcctgagagttgacgacacggccgtgtatttttgtgtgagagaatctaggagttggactggaagtacacttccagcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17356 JY8QFUQ01CCZ9F No results 17357 JY8QFUQ01CHKDL unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt Homsap IGHJ2*01 F (see comment) 76 60.38 32/53 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGFV# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggtttcgtggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17358 JY8QFUQ01BB0FV unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17359 JY8QFUQ01C2RIZ productive Homsap IGHV3-74*03 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDNDGWHGTIDRW in-frame + cctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggataacgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 17360 JY8QFUQ01BT8ZF unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 17361 JY8QFUQ01CCQ01 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17362 JY8QFUQ01CR8IO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [2.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17363 JY8QFUQ01COIAZ productive (see comment) Homsap IGHV3-48*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.37.11] CAKDRGGSAYPIFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 2 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) tctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccagactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17364 JY8QFUQ01C759P productive Homsap IGHV1-8*01 F 948 93.93 201/214 nt Homsap IGHJ1*01 F 188 84.62 44/52 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [0.17.38.11] CARGSLDYGGLPQHW in-frame + tggatacaccttcaccagttatgatatcaactgggtgcgacaggccgctggacaagggcttgagtggatgggatgggtgaaccctaatagtggtgccacaggctatgcacagaagttccagggcagagtcaccatgagcagggacacctccgaaagtacagcctacgtggagctgagcagcctgggatctgaggacacggccgtgtatttctgtgcgagaggctccctggactacggtggcctcccccagcactggggccagggcaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17365 JY8QFUQ01AOAKY No results 17366 JY8QFUQ01BV17P No results 17367 JY8QFUQ01A0ESJ productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggGcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17368 JY8QFUQ01CCA5W productive (see comment) Homsap IGHV3-48*01 F (see comment) 744 83.89 177/211 nt 83.41 176/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) tggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17369 JY8QFUQ01CX4H6 productive (see comment) Homsap IGHV1-3*01 F 899 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ctggatacagcttcactaactacaatatccattgggtgcgccaGggcccccggacaaaGggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17370 JY8QFUQ01CQ9WN productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17371 JY8QFUQ01AB3KI productive (see comment) Homsap IGHV3-11*01 F 862 89.67 191/213 nt 89.2 190/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17372 JY8QFUQ01C1CZW productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 17373 JY8QFUQ01BRPY0 No results 17374 JY8QFUQ01CO1A1 productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame - cctctggattcaagtttgatgattccggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggaatggtggtaagacaggttatggagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 17375 JY8QFUQ01ALEO5 No results 17376 JY8QFUQ01C6ZIX No results 17377 JY8QFUQ01A44PN productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame + tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17378 JY8QFUQ01CLFVV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [2.17.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttaCtttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17379 JY8QFUQ01AR39G unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccaccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17380 JY8QFUQ01BMQ8K productive Homsap IGHV3-7*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17381 JY8QFUQ01DI3XP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 17382 JY8QFUQ01B4V0J unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17383 JY8QFUQ01A3QU6 productive (see comment) Homsap IGHV3-69-1*01 P (see comment) 1011 97.2 208/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01A3QU6 ; 7 AA in Homsap_IGHV3-69-1*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17384 JY8QFUQ01DCAL1 productive Homsap IGHV3-9*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17385 JY8QFUQ01B8GAC No results 17386 JY8QFUQ01BIGUV No results 17387 JY8QFUQ01BSQSD productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17388 JY8QFUQ01C1XOG No results 17389 JY8QFUQ01CS77U unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 121 54.48 73/134 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons ctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17390 JY8QFUQ01B757D productive Homsap IGHV4-61*02 F (see comment) 569 73.3 162/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARECSNSKVGPRALDSW in-frame + Low V-REGION identity (73,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcaggccgccgggaaggggctggagtgggtcgggcgtgtctatatgactggctatgtcgagaacaatccatccctctccgggcgtctctccatgtcgattgacacggcgaagaatcagttttctatgacattgacttctgtgaccgccgcagacacggccctttatttttgtgcgagggagtgtagtaattcgaaagtcggaccgagagcgcttgactcctggggcccgggaagtctggtcaccgtatcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17391 JY8QFUQ01AQ8HA No results 17392 JY8QFUQ01BG2MU unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 17393 JY8QFUQ01AR97Q No results 17394 JY8QFUQ01BR1B9 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI## out-of-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17395 JY8QFUQ01B5WEN productive (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 728 82.33 177/215 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD6-6*01 F 1 8 8 21 8.8.21 [1.17.38.11] CAKDLGYSISSGASTHYYGMGVW in-frame - however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01B5WEN ; 7 AA in Homsap_IGHV3-69-1*01), and low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) cctctggattcgcttttggtgactatgccatgaactgggtccgccaggctccagggaggggcctggaatgggtctcatttgtcaccactactggcagttccacatattatgcagactccgtgaagggccgattcaccgtttccagagacgacgccaagaatctactgtatcttcagatgaccggcctgagagacggggacacggctacatattactgtgcgaaagacttggggtacagcatctcgtcgggggcctccacgcactactacggaatgggcgtctggggccaagggacaacggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17396 JY8QFUQ01AKOA9 productive Homsap IGHV4-61*02 F 924 91.36 201/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARAWNGDYEVGWFDPW in-frame - ctctggtgactccatcggtaatggaagttactactggagctgggtccggcagtccgccgagaagggactggagtggattggacatatctataccagagggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagccgacacgtccaagaatcagatctccctgaagttgacctctgtgaccgccgcagacacggccgtatattactgtgcgagggcgtggaacggtgactacgaggtgggctggttcgacccctggggccaggggaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17397 JY8QFUQ01B63VT unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [2.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) gtgtctgggttaaccttcagtgaggatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagtcattggaacaatggaaagacctttcactatgcagactccgtgaagggccgcttcgtcatctcccgagacaattccaagagcaccctatatttacaaatgaatagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17398 JY8QFUQ01CH5Y6 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [2.17.38.11] CGTSSRAWGADAFD#LG out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); agcctctgggctcagcgtcagtaactaccgcatggGgctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacgaccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctgggggccagggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17399 JY8QFUQ01DT4RJ productive Homsap IGHV3-7*03 F 851 88.07 192/218 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgccctggtccaggggcttcttcccccca 17400 JY8QFUQ01A3GBW No results 17401 JY8QFUQ01B52AE productive Homsap IGHV3-7*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17402 JY8QFUQ01B9B4O unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 97.33 219/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGRYDENYYELDF## out-of-frame - in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 151 to 151 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacCccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17403 JY8QFUQ01A68J9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1030 97.69 211/216 nt 97.22 210/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17404 JY8QFUQ01ADEWV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17405 JY8QFUQ01B5BSI No results 17406 JY8QFUQ01CAL5B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17407 JY8QFUQ01AECSW unknown (see comment) Homsap IGHV3-23*05 F 102 55.24 58/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcgtctttggcgactatgcgatgagctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17408 JY8QFUQ01DBCLU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [2.17.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 172 to 172 in the user submitted sequence), (cause frameshift); gcctcaggattcaccttcagtaggtactggatgcactggGgtccgccaagttccagggaaGggggccggtgtGgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgTtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17409 JY8QFUQ01BVZI4 unknown (see comment) Homsap IGHV3-72*01 F 106 53.44 70/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagtgaccactacatggactgggtccgccaggccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17410 JY8QFUQ01DJPGW unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt 82.35 182/221 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRWAATAGHGLL*LL# out-of-frame - stop codons Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'AC' (2 nucleotides at position 11 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GA' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); tctctggtggACtcccatcagtagtactcattactattggGggctggatccggcaggcccccagggaggggGActggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccCctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcggcaacggctggtcatggactactttgactactgggggccagggaatcgtggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17411 JY8QFUQ01A2V18 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17412 JY8QFUQ01B51EH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVGEQMIDAVSHNYAMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CATCAA' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagCATCAAtacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaaccCcctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgtgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17413 JY8QFUQ01AW4KK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17414 JY8QFUQ01BQHEK No results 17415 JY8QFUQ01BOC8J No results 17416 JY8QFUQ01B3E1A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17417 JY8QFUQ01BYXM8 No results 17418 JY8QFUQ01DSHPL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + ttctggattcagtcctaccgatttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17419 JY8QFUQ01AYWUO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1035 97.7 212/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGPHQYYFDY## out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17420 JY8QFUQ01BW9QL productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17421 JY8QFUQ01AZOKF No results 17422 JY8QFUQ01B4NOB unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 17423 JY8QFUQ01DFP0A unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 724 81.48 176/216 nt 81.02 175/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); tctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccCaagaacacactatatctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17424 JY8QFUQ01ABQTA unproductive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDDYGVFDS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctctgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctggaaatcaacagcctgagcgacgaggacacgtctgtgtattactgtgcgagagatgattacggcgtctttgactcctggggcccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaaggtcttccccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 17425 JY8QFUQ01CR3KB unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17426 JY8QFUQ01A7240 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 969 93.64 206/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 1 10 7 9 10.7.9 [1.17.38.11] CAAGTVLFDYW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagtatctattacagtgggagcaccttctacaacccgtccctcaagagtcgagtcaccatatccgtagacatgtccaggaaccagttctccctgaaaatgaagtctgtgaccgccgcagacacggctgtgtattactgtgccgccggcacggtcctctttgactactggggccacggaaacatggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17427 JY8QFUQ01BP7G7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17428 JY8QFUQ01AMWMT productive (see comment) Homsap IGHV3-48*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggGggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17429 JY8QFUQ01CATW3 No results 17430 JY8QFUQ01CBB71 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggaattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17431 JY8QFUQ01CO7CD productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + cctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactgggaccagggaacgctgatcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagccctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 17432 JY8QFUQ01CUPRA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17433 JY8QFUQ01BP8ET productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17434 JY8QFUQ01DW83E No results 17435 JY8QFUQ01BPU4M productive (see comment) Homsap IGHV4-61*01 F 978 94.09 207/220 nt 93.64 206/220 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGAYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 110 to 121 in the user submitted sequence), (do not cause frameshift); ctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17436 JY8QFUQ01AODKD No results 17437 JY8QFUQ01AU4JA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctgGgattcggcagcccccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17438 JY8QFUQ01A8VWO unknown (see comment) Homsap IGHV3-74*03 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgcggtcatcgcctgcctggtccagggcttcttccccca 17439 JY8QFUQ01A1P86 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 915 90.91 200/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - agcctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17440 JY8QFUQ01CD3BX productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 17441 JY8QFUQ01A2JAS productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F (see comment) 671 78.44 171/218 nt 77.52 169/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [2.16.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtgtctggtggctccatcgccacttatcattggtggAacttgggtccgccagaccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17442 JY8QFUQ01C2FWS unproductive Homsap IGHV3-7*01 F 917 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*02 F 3 7 8 X 7.8.X [1.17.38.11] CARGSYWHYDTFGDY#W out-of-frame - in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) ctctggatttacttttacaactattggatgacctgggttcgccaggntccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactatttggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17443 JY8QFUQ01C7QDY No results 17444 JY8QFUQ01AV6MQ productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17445 JY8QFUQ01CI50M No results 17446 JY8QFUQ01BJBWT productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 17447 JY8QFUQ01AW35M unknown (see comment) Homsap IGHV4-61*02 F (see comment) 350 67.46 114/169 nt 10 7 X 10.7.X [0.17.21.X] null - No rearrangement found Low V-REGION identity (67,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacagtgtacaacccctcccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17448 JY8QFUQ01CI80K productive (see comment) Homsap IGHV2-5*02 F 1179 98.36 240/244 nt 96.72 236/244 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 10 7 15 10.7.15 [9.17.38.11] CAQKGEIDTYGPKYDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcagcactagtggagtgGggtgtgggctggCatccgtcagGcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagtccatctctgaagagcagactcaccatcaccaaggacacctccAaaaaaccaggtggtccttacaatgaccaacatgaaccctatggacacagccacatattactgtgcacagaagggggaaatagacacctatggccccaaatatgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17449 JY8QFUQ01BOGW2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt 85.59 190/222 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17450 JY8QFUQ01CWQZU productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagccctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttcccc 17451 JY8QFUQ01BXMUH unproductive Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY## out-of-frame + in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaAaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcag 17452 JY8QFUQ01A723I productive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-3*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDDDFWNGKHFDPW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 86 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggAaaggggctggagtgggtggccaatataaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagagacgacgatttttggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17453 JY8QFUQ01BZ1GY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 17454 JY8QFUQ01B5QF3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattccCcctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17455 JY8QFUQ01DDDB8 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 17456 JY8QFUQ01CANL1 productive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 109 66.07 37/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 17457 JY8QFUQ01AV2J9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17458 JY8QFUQ01BBSRC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 34 of V-REGION: 'ACC' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift); tctttggtgactctctgagtACCagtagcagtttctactggggctgggtccgccaggccccagggaagggactggagtgggttgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccaaaaccaggtctccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgaggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17459 JY8QFUQ01DSJUE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 645 83.15 153/184 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.15.38.11] DSRNPRV# out-of-frame - Low V-REGION identity (83,15% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggggtccgccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17460 JY8QFUQ01DHTRO unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVRGYYGGQYFDSW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggGaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggcccaggggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcgcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 17461 JY8QFUQ01DIPXM productive Homsap IGHV1-69*04 F, or Homsap IGHV1-69*09 F or Homsap IGHV1-69*11 F (see comment) 660 78.97 169/214 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAKERDYGSGTYNWFDPW in-frame + Low V-REGION identity (78,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgggggcgtcttcaattattatgctattaattgggtgcgacaggcccctggacaagggcttgagtggatgggaaggatcagacctattcaaaatctggtaaactacgcacagacttttgagggcagagtcaccctcaccgcggacgagtctacgaacacagtgtacatggaactgaccaggttgacttccgcggacacggccttttactactgtgcgaaagagagagactacgggtcggggacttataactggttcgacccctggggccagggaacccgcgtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17462 JY8QFUQ01DPP8C productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-14*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARHLQYNRHGFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtagtcattactactggggctggatccgccagaccccaggaaAaggggctggagtggcttgggacaatctattatagcggaagcgcctacatcaacccgtccctcaagagtcgagtcaccatttccgttgacatatctaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattactgtgcgagacacctgcaatataatcgacatggttttgatttctggggccaggggacaacggtcaccgtctcttcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17463 JY8QFUQ01B5K0B productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagtacctataacatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttctccctggcaccctcctccaagagcacctctggggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17464 JY8QFUQ01DRXQO productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 988 96.24 205/213 nt 95.77 204/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.16.38.11] CAREDGSGRRHFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagtagttactactggagctggatccggctgccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17465 JY8QFUQ01BW3P7 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17466 JY8QFUQ01CP3MY productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 7 14 8.7.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ggttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17467 JY8QFUQ01DMOXB productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 7 18 8.7.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DMOXB ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift); cctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggGggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacAaccctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggctccagggcttcttcccccag 17468 JY8QFUQ01A9R46 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 982 94.52 207/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKDFTYAFDLW in-frame - gcgtctggattcacgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctccgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17469 JY8QFUQ01BTW3T No results 17470 JY8QFUQ01DORH9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 17471 JY8QFUQ01CP1JK productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgcaaccggtgacggtgtcgtggaaact 17472 JY8QFUQ01A3HFQ unknown (see comment) Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found gcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17473 JY8QFUQ01CO93B unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 418 96.63 86/89 nt 8 3 X 8.3.X [1.17.X.X] null - No rearrangement found ctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagta 17474 JY8QFUQ01CJP3R productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt 87.1 189/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.16.38.11] CVRDSGPSGYARYESMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) cctctggattcagcctcacttcctatggcatgaactgggtccgccagctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17475 JY8QFUQ01A0BNB unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPHFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17476 JY8QFUQ01AJ8VO unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDRRGYSYEMDY## out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17477 JY8QFUQ01CSRVY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 17478 JY8QFUQ01BT86E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17479 JY8QFUQ01APUS4 productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17480 JY8QFUQ01B73FI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 738 82.49 179/217 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17481 JY8QFUQ01CRWPM unknown (see comment) Homsap IGHV3-74*03 F 113 54.33 69/127 nt 8 8 X 8.8.X [1.17.7.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17482 JY8QFUQ01BCUIL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17483 JY8QFUQ01A98PF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17484 JY8QFUQ01ASBBA productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17485 JY8QFUQ01CHTSN productive (see comment) Homsap IGHV3-7*02 F 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 146 to 146 in the user submitted sequence), (cause frameshift); ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatgggaCgtgaggcatactatgTcggactctgtgaagggccgattcaccatctccaCgagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17486 JY8QFUQ01C9U1A unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.17.38.11] CAREGGRGYDMDV## out-of-frame - in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtatctatgccatgacctgggtccgccaggctccagggaaggggctggagtggatttcatttatcactgataGggggtagtacccaatactacgcagactctgtgaagggccgattcaccgtctccagggaccaagccaagaactcactgtatctacaaatgaacaacctgggagtcgaggacacggctgtgtattattgtgcgagagaggggggacgtggctacgatatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17487 JY8QFUQ01BXMPA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17488 JY8QFUQ01BWEN5 productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-13*01 F 1 10 7 18 10.7.18 [1.17.38.11] CARDRYVVDSSWYGNFFDPW in-frame + tctctggtggctccatcagcagtggtacttactactggagctggatccggcagcccgccgggaaggcactggaatggattggacatatctctaccagtgggagtaccacctacaacccctccctcaagagtcgagtcaccatatcagctgacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcagacacggccgtgtattattgtgcgagagatcgatatgtcgtggacagtagctggtacggcaactttttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17489 JY8QFUQ01ANBVT No results 17490 JY8QFUQ01ATJJ5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17491 JY8QFUQ01DXAFD unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGGGGMTIPLDK## out-of-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctccaggcaaggggctggaatggttggctgctatatggtatgatggaagtaataagtattatgcagactccgtgaggggccgattcaccatttccagagacaattccaagaacactctgtatctgcaaatgaatgacttgagagacgaagatacggctttttattcttgtgcgagaggcggcggtggtatgaccattccacttgacaaatggggccgggggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17492 JY8QFUQ01C1E74 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17493 JY8QFUQ01CZ478 productive (see comment) Homsap IGHV1-2*02 F 812 86.85 185/213 nt 86.38 184/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.16.38.11] CARCLWISGTYHFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatatactttcaccgaccattatgtttactggatgcgacaggccctgganaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17494 JY8QFUQ01AMSPA unknown (see comment) Homsap IGHV3-21*04 F (see comment) 667 78.54 172/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (78,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactgggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17495 JY8QFUQ01AHIDS productive (see comment) Homsap IGHV3-48*01 F 1008 96.31 209/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaAGggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccAaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17496 JY8QFUQ01CA9EZ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD5-18*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARSQSRYSWGDFLHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtactagttactactggggctggatccgccagcccccagggagggggctggagtggattggaagcatctattatagtgggagcacctcctacaacccgtccctcaagagtcgaatcaccatgtccatagacatgtccAaagaaccaattctccctgaggctgagctctgtgaccgccgcagacacggctgtttatttctgtgcgcggtcccagagtagatacagttggggtgacttcttacactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 17497 JY8QFUQ01CROTA No results 17498 JY8QFUQ01C6QGX productive (see comment) Homsap IGHV3-48*01 F (see comment) 764 84.19 181/215 nt 83.26 179/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17499 JY8QFUQ01ADUEL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17500 JY8QFUQ01AXW72 productive (see comment) Homsap IGHV4-61*02 F (see comment) 753 82.73 182/220 nt 82.27 181/220 nt Homsap IGHJ4*02 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-16*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARERGASIGEAGGLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) tctctggtggcccgtcaacaatggtgatcagtattggagctggatccggcagcccgccgggaaggggctggagtggatcggacgtgtttctgctagtgggacctacagctacaatccctccctcaggagtcggatcaccatctcaatagacatgtctaagaatcacttctccctgaggttgatttctgtgacggccgcagacacggccttatattattgtgcgagagagcgtggtgcgtcgattggcgaagcgggaggccttgactcctggggccagggaaccctggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17501 JY8QFUQ01A2H3P No results 17502 JY8QFUQ01CPGSM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 17503 JY8QFUQ01CBBZ2 unproductive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD1-1*01 F 1 10 7 X 10.7.X [1.17.38.11] CAREKVVIRPNWFD#PW out-of-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgaccccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17504 JY8QFUQ01A26DA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 768 82.96 185/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYHSTYPW in-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17505 JY8QFUQ01BF5VH unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGEFYYETSGRRG#FDYW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaGggggctaatgtgggtcgcacgtattaataAgggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaagggggttttgactactggggccagggaaccctggtcatccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17506 JY8QFUQ01AGAPD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [2.17.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagttataGgcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17507 JY8QFUQ01C5CQD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F, or Homsap IGHJ5*02 F 73 61.7 29/47 nt Homsap IGHD5-18*01 F 3 8 8 5 8.8.5 [1.17.38.11] CASYGQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggcagggacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 17508 JY8QFUQ01BJ7YX unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCL#GAFDIW out-of-frame - in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccCttatcactagacacgtccaagaaccagttctcCcctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgtttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17509 JY8QFUQ01AH2WS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGRG in-frame - ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtcgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17510 JY8QFUQ01C5UQJ No results 17511 JY8QFUQ01CE7G4 productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17512 JY8QFUQ01A0S1H productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 17513 JY8QFUQ01DKQ2M unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-15*01 F 3 8 10 X 8.10.X [1.17.38.11] CAADGCPGGTCYHGFDM## out-of-frame - ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17514 JY8QFUQ01B5EZ8 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 917 90.18 202/224 nt 88.84 199/224 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD6-6*01 F 1 8 10 X 8.10.X [1.17.38.11] CTSNSWLDR## out-of-frame + in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'GC' (2 nucleotides at position 79 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'AG' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift); cctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggGAagggggctggaatgggttggGCccatattaaaaAGgggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaaccccccgtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17515 JY8QFUQ01ALDNB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgctggtccagggcttcttccccca 17516 JY8QFUQ01CXJ4R productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17517 JY8QFUQ01AWBYK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 747 82.49 179/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17518 JY8QFUQ01CLNA3 No results 17519 JY8QFUQ01BS0MI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctctggattcgccttcagttggtattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgntgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttcttcccc 17520 JY8QFUQ01DKRI1 productive Homsap IGHV3-21*04 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17521 JY8QFUQ01CKLRC productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17522 JY8QFUQ01C4FP2 No results 17523 JY8QFUQ01CYOQ9 productive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 163 76.79 43/56 nt Homsap IGHD6-13*01 F 3 8 10 10 8.10.10 [1.17.38.11] CARAVSHQVDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtgcgagagccgtgtcgcatcaggtggacgtctggggccaaggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcnacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17524 JY8QFUQ01CMHJ0 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17525 JY8QFUQ01AKTN5 No results 17526 JY8QFUQ01BEQKB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccccatggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 17527 JY8QFUQ01C0WDO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17528 JY8QFUQ01C7DRB productive Homsap IGHV4-4*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcgccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17529 JY8QFUQ01B8I95 No results 17530 JY8QFUQ01BCJ3M unproductive Homsap IGHV3-48*03 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRADLFYDSSGYQFDL## out-of-frame + ctctggattcatcttcagcgatcatggaataaactgggtccgccaggctccggggaagggtctggagtggatttcattcgtcagtagtaggggtgggaccatccactacgcagactctgtgaagggccgattcatcatctccagagacaactccaggaacacagtatttctacaactgaacagactgagagacgaagacacggctatttattattgtgcgagagacagggcggatttgttctatgatagcagtggttaccaatttgatctttggggcccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17531 JY8QFUQ01BAG1V productive Homsap IGHV1-3*01 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CVRGRSPPGDWFDPW in-frame + tggatacaccttcactaattatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17532 JY8QFUQ01CBLPY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccGagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17533 JY8QFUQ01BPLZQ unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 101 53.08 69/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons tctggattcaccttcagtaactatagcatgaactgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17534 JY8QFUQ01BFZ6J productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17535 JY8QFUQ01B0ZM2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17536 JY8QFUQ01CJWXE No results 17537 JY8QFUQ01BNS5M productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 962 92.41 207/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17538 JY8QFUQ01AHMBY unproductive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD1-26*01 F 1 9 7 X 9.7.X [1.17.38.11] CARSFESYHPNVALDI## out-of-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); ctccggaggcctccatcagcactattcattggtggaattgggtccgccagTcccccgggaaaggggctggagtggattggagaagtctatcatagtgggaacaccaactataacccgttcctcaagagtcgagtctccattgcagtcgacaaggccaagaaccaggtctccctgactgtgacgtctgtgaccgccgcggacacggccacatatttctgtgcgagaagttttgagagctaccatccaaatgtcgctttagacatctgggggccaagggacaagggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17539 JY8QFUQ01C5XWP No results 17540 JY8QFUQ01A1BXP unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 927 92.17 200/217 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctactggatgcaactgggtccgcaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagctcgacagcacccccccaagatgggaacntggtcgtcgcatgcctggtccagggcttcttccccc 17541 JY8QFUQ01C1MKT productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*07 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-14*01 ORF 3 8 8 12 8.8.12 [1.17.38.11] CARVHRNSMNFDYW in-frame + ctctggattcgccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatatgatggaagtaatgaatactacgcagactccgtgaagggccgattcaccatttccagagacatttccaacaacacgctgtatctgcaaatgaacagcctgagagcggaagacacggctgtgtattactgtgcgagagtccaccgtaacagcatgaattttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaa 17542 JY8QFUQ01AJTUX productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 630 93.1 135/145 nt 92.41 134/145 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 7 16 8.7.16 [1.17.14.11] CARGPVGISESVNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 73 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagaggtccggttgggataagtgaaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17543 JY8QFUQ01AFVUY productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARFSGSYKSAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ggttctggatacatctttaccgactattggatcggctgggtgcgccagacggccgggaAaaggcctggagtggatgggaatcatctatcctggtgactctgacaccagttatggcccgtccttccaaggccaggtcaccatttcagccgaccagtccatcaccaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagattcagtgggagttacaaatcggcttttgatatctggggccgagggacaatggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17544 JY8QFUQ01CCBVJ unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 435 76.67 115/150 nt 8 7 X 8.7.X [1.17.16.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CCBVJ ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,67% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag 17545 JY8QFUQ01C7QF9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17546 JY8QFUQ01CIV0V productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 964 93.61 205/219 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17547 JY8QFUQ01DQKT0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17548 JY8QFUQ01A8UPT No results 17549 JY8QFUQ01DJBIE productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARRDVGSHAFDLW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ttctggatacaattttaactacgactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatggtctatgttgGgtgactctgatgctagatacagcccgtcctccgaaggccaggtcaccatctcagccgacaaggccatcagtaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggatgtgggttcacatgctttcgatctgtggggccaagggacaatggtcaccgtttcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 17550 JY8QFUQ01C0X2L No results 17551 JY8QFUQ01CPAEA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 661 78.24 169/216 nt 77.78 168/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (78,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggaGgggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17552 JY8QFUQ01DUZ2M unknown (see comment) Homsap IGHV1-2*02 F 512 87.22 116/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatgcatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc 17553 JY8QFUQ01CNQBQ No results 17554 JY8QFUQ01BW8SZ productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17555 JY8QFUQ01ANU9C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17556 JY8QFUQ01AQT5K productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17557 JY8QFUQ01AXWVT No results 17558 JY8QFUQ01B7UKL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17559 JY8QFUQ01DSTHX productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17560 JY8QFUQ01CF57Z productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17561 JY8QFUQ01AFFU5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17562 JY8QFUQ01AJWRX unproductive (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKEEF*HWLDTTG##W out-of-frame + stop codons cctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaattttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgaccagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17563 JY8QFUQ01CYV58 productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 83 to 88 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacgGggcccctggacAaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17564 JY8QFUQ01BT3X8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1090 95.78 227/237 nt 95.36 226/237 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 166 74.19 46/62 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [8.17.38.11] CAKGRGYSRDLVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctgagactctcctgtgcagcctctggattcacAttttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaggtgtcagtggtagtggtgataagacatactacgcagacttcgtgaagggccggttcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagggaggggttatagcagagacttggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgttgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17565 JY8QFUQ01AEL64 unproductive (see comment) Homsap IGHV3-72*01 F 944 91.52 205/224 nt 90.18 202/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'GC' (2 nucleotides at position 30 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); cctctggattcaccttGaagtgatcactaGCatgggactgggtccgccaggctccaAgggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17566 JY8QFUQ01AEGV0 productive Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17567 JY8QFUQ01CGT9A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRIVSVGMAGWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); tctctggattcaccttcaggaactattggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacacgctgtatctgcaaAatgaacagtctgagagccgaggacacagccgtatatttttgtgtaagaggccgtatagtgtcagttggtatggcaggctggttcgacccctggggccagggaacgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17568 JY8QFUQ01B4SR5 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 84.4 184/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKDYGNCAGGRCYSIP##DYW out-of-frame + stop codons in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'GTTT' (4 nucleotides at position 99 to 102 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccgggAaaaggggctggagtgggtctcaggcatcactgatggtggtggGTTTtttgacatactacgcagacgccgtgcagggccggtttattatttccagagacgattcccagaacacgatagatctgcaaatgaacaatttgagagccgacgacacggccatctattactgtgtgaaagattacggcaattgtgctggtggtcgctgctactcgattccccgttgactattggggccggggaaccgtggtcaccgtctcctcagcatccccgaccagcccccaaagggtcttcccgctgagcctcgacaacacccccctaagatgggaacgtggtcgtcgcatgcctggtccaggcttctcccca 17569 JY8QFUQ01BBVME productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17570 JY8QFUQ01DSXV6 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [0.17.38.11] CATDRCTGGTCCPHYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AC' (2 nucleotides at position 84 to 85 in the user submitted sequence), (cause frameshift); tggatacactttcaccagttattatatacactgggtgcgacaggACcccctggacaggggcttgagtggatgggagttgtcaaACccctggtgctgaatacacactctacgcacagaagttccagggcagactcaccttgaccagggacacgtccacgagcacagtctacatggagttgagtagcctgagatctgaggacacggccctgtattactgtgcgacagataggtgtactggtggtacctgctgtccacattactggggccagggaaccctgatcaccgtctcctcagcctccaccaagggcccatcggtcttaccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17571 JY8QFUQ01CY1GJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17572 JY8QFUQ01DXEI5 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17573 JY8QFUQ01C4CFG productive (see comment) Homsap IGHV3-48*01 F 797 85.32 186/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggcgctggagtggAttttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17574 JY8QFUQ01B2RHD unproductive Homsap IGHV3-48*02 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ6*01 F 104 65.45 36/55 nt Homsap IGHD3-22*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDHNWAYDY# out-of-frame + in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcagtttcagtagctacaatgtaaattggatccgccaggctccagggaaggggctggagtggatttcatacattagtactactaatgccatatactacgcaaactctgtgaggggccgattcaccatctccagagacaatgccatgaactcattgtatttgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagatcacaattgggcatatgactactggggccagggaaccctgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17575 JY8QFUQ01ACD88 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 929 91.4 202/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'GT' (2 nucleotides at position 80 to 81 in the user submitted sequence), (cause frameshift); gccctcctggattGcaccttGcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtcGTacccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17576 JY8QFUQ01BLTS4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 823 86.64 188/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'T' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tcaggattgcaccttcagtaggtactggatgcactgggtccgccaagttccagggGAagggggccggtntgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaaTgggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 17577 JY8QFUQ01C1WLX productive (see comment) Homsap IGHV1-8*01 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ1*01 F 188 84.62 44/52 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [0.17.38.11] CARGSLDYGGLPQHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttatgatatcaactgggtgcgacaggccgctggacaagggcttgagtggaAtgggatgggtgaaccctaatagtggtgccacaggctatgcacagaagttccagggcagagtcaccatgagcagggacacctccgaaagtacagcctacgtggagctgagcagcctgggatctgaggacacggccgtgtatttctgtgcgagaggctccctggactacggtggcctcccccagcactggggccagggcaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17578 JY8QFUQ01CXOYT unknown (see comment) Homsap IGHV1-NL1*01 P 90 56.79 46/81 nt 2 X X 2.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagagac 17579 JY8QFUQ01CF4SX productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [2.17.38.11] CARLPNTIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); gcgttctggatatagttttgGccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatCgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17580 JY8QFUQ01CE7H7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17581 JY8QFUQ01B7YG7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17582 JY8QFUQ01CJN3R No results 17583 JY8QFUQ01CQCUX productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1025 95.54 214/224 nt 95.09 213/224 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CARHEGTPVSDVGGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaAaagggctggaatgggttggccgtattagaagcagagctcacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggccaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17584 JY8QFUQ01ACXAI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17585 JY8QFUQ01CATB8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 84.26 182/216 nt 83.8 181/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.16.38.11] CAKDTITMGGDVAPLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tctgggattcacctttagtaactatgacatgggctgggtccgccagctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17586 JY8QFUQ01BEMMN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17587 JY8QFUQ01AIBEO No results 17588 JY8QFUQ01BVAYX productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 82.81 183/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccCatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc 17589 JY8QFUQ01C80D8 No results 17590 JY8QFUQ01B9KSC No results 17591 JY8QFUQ01DRCW3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 917 92.09 198/215 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARDLRARLWHPMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaatagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17592 JY8QFUQ01CX6IA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 804 86.45 185/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CGTSSRAWGADAFDIW in-frame + ctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcagttatttatagagatgatagtacagatcatgtagattccgtgaagggccgattcaccgtttcccgagacaattccaagaacacattgtaccttcagatgaacagtgtgacagccgaggacacggccgtttattattgtggaactagttcccgcgcctggggcgctgatgcctttgatatctggggccaggggacactggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17593 JY8QFUQ01DOVD6 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 103 62.9 39/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17594 JY8QFUQ01BK9D5 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.37.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattatactgggggcaccgactccaaccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcacctgcctggtccagggcttcttccccca 17595 JY8QFUQ01BWD62 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'GA' (2 nucleotides at position 79 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tatatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggGAaaatcaatcacagtggaaCgccccaactacagcccgtccctcaatagtcgagtcatcatatcgatagacacgtccaagaaccaggtctccctgaagctcttctctgtgaccgccgcggacacgggtgtgtactattgtgcgaggcccacgtatagtagcggccgggacgcctttgatacctggggccaagggacgacggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 17596 JY8QFUQ01ABNP9 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17597 JY8QFUQ01AOZ1H productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17598 JY8QFUQ01BGBRB unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 641 85.14 149/175 nt 84.57 148/175 nt 8 8 X 8.8.X [0.17.25.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagggcttcttccccca 17599 JY8QFUQ01BU594 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 799 84.68 188/222 nt 81.53 181/222 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARTYTYRNAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,68% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 34 of V-REGION: 'ACC' (3 nucleotides at position 22 to 24 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'AG' (2 nucleotides at position 41 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'GG' (2 nucleotides at position 112 to 113 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'GG' (2 nucleotides at position 166 to 167 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 184 to 184 in the user submitted sequence), (cause frameshift); tcctttggtgactctctgagtACCagtagcagtttctactAGggggctgggtccgccagGaccccagggaagggactggagtgggttgggactgtttattatagtgggagcGGccccactacaatccgtCccctcaagagtcgagtcgccatatccgtggacacgGGccccaaaaccaggtctCccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcaccccagccagatgagggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17600 JY8QFUQ01B22B8 unknown (see comment) Homsap IGHV4-31*06 F, or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*04 F 139 58.88 63/107 nt 10 7 X 10.7.X [1.17.X.X] null - No rearrangement found tctctggtgcctccgtcagcagtggtagtttctactggacctggattcgtcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttccca 17601 JY8QFUQ01AL1BT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctctagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17602 JY8QFUQ01C8VWW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [1.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01C8VWW ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccCgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17603 JY8QFUQ01BN0XS productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17604 JY8QFUQ01AY4XZ productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 678 79.91 171/214 nt 79.44 170/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17605 JY8QFUQ01CK6XO productive (see comment) Homsap IGHV3-66*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgGggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17606 JY8QFUQ01AGSLZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacatggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17607 JY8QFUQ01DF9CL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17608 JY8QFUQ01B9WA9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt 85.78 187/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDDGGHMTLDVW# out-of-frame + in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGgggcacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctgggggcccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggcccctgggctncctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17609 JY8QFUQ01ASM68 productive (see comment) Homsap IGHV3-7*01 F 922 92.13 199/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 78 in the user submitted sequence), (cause frameshift) cctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17610 JY8QFUQ01B2Q5F productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 17611 JY8QFUQ01CHDJL productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 17612 JY8QFUQ01AMLKN productive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGKAGHTHYGLDVW in-frame + cctctgcattcaccttcagtagttatgctatgcactgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17613 JY8QFUQ01AGHU9 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 17614 JY8QFUQ01BBOR9 productive Homsap IGHV3-21*04 F 990 95.39 207/217 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F 172 78.57 44/56 nt Homsap IGHD6-13*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARAVSNQVDVW in-frame + ctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcgagagccgtttcgaatcaggtggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17615 JY8QFUQ01COWTP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggaccagggagcctggtctccgtctcctcagcatccccgaccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgcctggtccagggcttcttcccc 17616 JY8QFUQ01ACVT5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtccgtcgcatgcctggtccagggcttccttcccccgag 17617 JY8QFUQ01C7QDR No results 17618 JY8QFUQ01AYI9R productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*07 F (see comment) 738 82.49 179/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-13*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAREADGQDLTTHLNWFDPW in-frame - Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatcttcagtgcctacgctatgcactgggtccgcctgtctccaggcaggggcctagagtgggtggcaggaatctcacacgatggcagtcagacagactacgcagcctccgtgaagggccggttcatcatttctagagacaattccaaagacacagtgtttctggaaatgaaaagcctgggcggagaagacacggctgtttactattgtgcgagagaagcagatgggcaagacctgacgacccacttgaactggttcgacccctggggccagggaatccaggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17619 JY8QFUQ01BGAZN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 843 87.27 192/220 nt 86.82 191/220 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); cctccgggagttcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatGagtatggggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17620 JY8QFUQ01CYLN8 No results 17621 JY8QFUQ01AK8CV unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaGggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 17622 JY8QFUQ01BWSIV No results 17623 JY8QFUQ01B231X productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17624 JY8QFUQ01AGYY9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17625 JY8QFUQ01CRBLN productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17626 JY8QFUQ01BE2KX unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc 17627 JY8QFUQ01CXQX3 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARKESPRGDFLW#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 17628 JY8QFUQ01BM9DJ productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcagcaactactatagacactgggtgcgacaggACcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17629 JY8QFUQ01C1YPN unproductive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 933 91.82 202/220 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CAAYDSGWYKH## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctggagtggattggatacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtttaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactgggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17630 JY8QFUQ01ALZ5E No results 17631 JY8QFUQ01BN3NW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccCagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggcccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17632 JY8QFUQ01BZS1D productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1033 96.4 214/222 nt 94.14 209/222 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.37.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'CA' (2 nucleotides at position 196 to 197 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 80 of V-REGION: 1 nucleotides (from position 151 in the user submitted sequence), (cause frameshift) ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaAaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaaggatgattccaAaaagcatcgcctatctgcGaaatgaatagcctgCAaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17633 JY8QFUQ01AKHUT unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 481 94.39 101/107 nt 8 8 X 8.8.X [1.17.1.X] null + No rearrangement found ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatact 17634 JY8QFUQ01CSM2A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggGaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17635 JY8QFUQ01BYVM2 productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + ctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17636 JY8QFUQ01ADLGV productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [1.16.38.11] CATSRGSANWYPFDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'A' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgcctctggcataAaactgggtccgccaggctccagggaaggggctggaatgggtctcatcatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaacAtcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17637 JY8QFUQ01BOX0R productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17638 JY8QFUQ01BSSC9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttacccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17639 JY8QFUQ01DGGVK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [1.17.38.11] CAKDIWAREWNDMAAFQMW in-frame + Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactca 17640 JY8QFUQ01BP5LW productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17641 JY8QFUQ01BLU5T unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 90 81.48 22/27 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctccgggggacagtgtctctagcagca 17642 JY8QFUQ01AMCQ7 productive (see comment) Homsap IGHV4-34*13 F (see comment) 646 78.4 167/213 nt 77.93 166/213 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [2.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctgatggggtcgttcatgggttacctctggaattGggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17643 JY8QFUQ01AJT2G No results 17644 JY8QFUQ01A1TLL unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 102 53.03 70/132 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17645 JY8QFUQ01BX21F unproductive (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKEEF*HWLDTTG##W out-of-frame + stop codons cctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaattttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17646 JY8QFUQ01A4HRX unknown (see comment) Homsap IGHV3-23*05 F 99 52.59 71/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons cctctggatacagttttaacagttatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17647 JY8QFUQ01BUHDG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDRLTISALDY## out-of-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17648 JY8QFUQ01DNVXO unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 796 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGA#LDYW out-of-frame + stop codons tctggattcaccttttccaactgtgacatgagctgggcccgccagattccagggaaggggctggagtgggtctcagttatttctggaggtgattttggaacatctgacgcagactccctgaagggccggttcaccatctccagagacaattccaaggacacgttgtgactgcaaatgaaccgcctgagagccgaggacacggccctatatatgtgtgccggggcccttggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcagg 17649 JY8QFUQ01CSU3T No results 17650 JY8QFUQ01CEW67 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17651 JY8QFUQ01DFDL8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGMYASGWA#FDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcagttttagtagtcatggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaggtgttagtagtgctgatggccggacacactacgcagagtccgtgaagggccgattcatcatctccagagtcaattacgagaataccctgtacctgcaaatgaatgacctgacagccgaggacacggccgtttattattgtgcgaaagggatgtatgccagtggctgggcccctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17652 JY8QFUQ01B0QYK productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17653 JY8QFUQ01C1E0F productive (see comment) Homsap IGHV3-7*01 F 960 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); agcctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17654 JY8QFUQ01CGZ5P unproductive Homsap IGHV4-4*07 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREGLLWFGELWAG#WFDSW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'GCAGTG' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tctctggaggctccatcaGCAGTGgaagttactactggacctggatccggcagcccgccgggaagactctggagtggaTttgggcgcttctacagtcgtgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagagggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17655 JY8QFUQ01A3KRW unproductive Homsap IGHV3-30*06 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [2.17.38.11] CARDPDSTGSLWFFDH## out-of-frame + gcgtctggattcaccttcactagttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatctcaaatgatggaagaaataaatactacgcagactccgtgaagggccgattcagcatctccagagacaactccaagaacatggtgtatctgcaaatgaacaacctgagagttgaggacaccgctctcttttattgtgcgagagacccagacagtactggttctttatggttctttgaccattggggcccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17656 JY8QFUQ01A1B2W productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 1 10 7 19 10.7.19 [1.17.38.11] CARQLEEGREVLQWNDAFAIW in-frame + tctctggtggctccatcaacagtagtagttatcactgggcctggatccgccagcccccagggaagggactggaatggattggcagtatgtcttatagtggggacacctactacaatccgtccctcaagagtcgagtcgccatatccgcagacacgtccaggaaccggttctccctgaagttgagctctctgaccgccgcagacacggctgtatattactgtgcgagacagcttgaggagggacgggaggtactccaatggaatgatgcttttgctatctggggccaggggacagtggtcaacgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17657 JY8QFUQ01B1I9P productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggcGtggagtgggtctgctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17658 JY8QFUQ01BIG2J No results 17659 JY8QFUQ01A078O No results 17660 JY8QFUQ01AT8GZ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [0.17.38.11] CARGDGYNFGGLDYW in-frame - ctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17661 JY8QFUQ01AOXDB No results 17662 JY8QFUQ01CNDKC productive Homsap IGHV3-7*01 F 887 89.45 195/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17663 JY8QFUQ01A4E2R productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 924 93.36 197/211 nt 91.94 194/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 13 7.8.13 [X.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift) gattcacctttggttattGatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17664 JY8QFUQ01BY6TV productive Homsap IGHV3-7*01 F 886 90.28 195/216 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame - tctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17665 JY8QFUQ01B70AV productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 843 89.1 188/211 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [0.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17666 JY8QFUQ01BNRZG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 698 80.28 175/218 nt 79.82 174/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAKGLRSRLESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'ATATCT' (6 nucleotides at position 102 to 107 in the user submitted sequence), (do not cause frameshift); cctctggatttagtttcagcggaagttggatgtactgggtccgccagggtccaggtaagggtctggagtggctgtcacgtaataaagttgcaggaactactATATCTacaagttatgcggactccgtgaggggccgattcaccgttaccagagacggcgccaagaataccatctatctgcaaatgaacagtctgacagtcgacgacacggctgtgtattattgtgcgaaaggacttaggagtcgccttgagtcctggggccagggagtcgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17667 JY8QFUQ01ARBIS No results 17668 JY8QFUQ01AMDQK productive (see comment) Homsap IGHV4-4*07 F 782 85.12 183/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'CAA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtcCAAaaccagtggggagccccccactacaacccttccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccatttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17669 JY8QFUQ01BLXF8 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17670 JY8QFUQ01B4SAK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17671 JY8QFUQ01BPX3E unproductive Homsap IGHV3-21*04 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.16.38.11] CVKDMVAGQGLLSRFDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 2 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) cctctggattcagcttaagttcttatggcatgaactgggtccgccaggctccaggggggggctgagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactgggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 17672 JY8QFUQ01CKKB5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17673 JY8QFUQ01AQ18D productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 14 8.10.14 [1.17.38.11] CTTDPRYFWGSGFDYW in-frame + ctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtaccaccgatccccgttacttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 17674 JY8QFUQ01B52FN No results 17675 JY8QFUQ01BCWT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctttggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 17676 JY8QFUQ01CYPIH unproductive Homsap IGHV3-7*01 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CATSPSDFDRRWG#YW out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatggggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17677 JY8QFUQ01ANU0J unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFWRFLQFSGLL# out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 17678 JY8QFUQ01AWOLO productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17679 JY8QFUQ01BBXBF productive (see comment) Homsap IGHV3-7*03 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [2.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'GC' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); gcctccggattGCaatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17680 JY8QFUQ01BKDXY unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 410 83.05 98/118 nt 82.2 97/118 nt 8 7 X 8.7.X [1.17.5.X] null + No rearrangement found Low V-REGION identity (83,05% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) tctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccatttctacgcagagtctgt 17681 JY8QFUQ01B99ZE productive (see comment) Homsap IGHV4-34*03 F 885 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.16.38.11] CVRNYYDFSGYFNWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tgtctggtgggtccttcagtggttactactggagttggatccgccagccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17682 JY8QFUQ01ADOTV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F (see comment) 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17683 JY8QFUQ01B1ODF unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD2-15*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDPRDYCSGGYCFVGAFDI# out-of-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaaggGgactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaaggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaaactc 17684 JY8QFUQ01CBOKC productive Homsap IGHV3-7*01 F 851 88.07 192/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17685 JY8QFUQ01BN3MT No results 17686 JY8QFUQ01AJDOZ unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 743 82.57 180/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CATDLVTSTPGVPR*CLCLL## out-of-frame + stop codons Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggaatcacgttcaacagacatggcattcactgggtccgccaggcccctggcaggggcctggagtgggtggctgttatgtcccgagacggaagtagacaatactatagagactccgtgaagggccgtttcgccatctccagggacacttccacgaacactgtgtatctgcaaatgaacagtctgagagttgacgactcggctctatatcgctgtgcgacagacttggtgacctccacaccgggagtccctcgatgatgcttatgccttttgggggccaaaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcggcctgcctcggtctagggcttcttccccc 17687 JY8QFUQ01BDK3Q unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRVGAAILRFLEWLSD#NWFDPW out-of-frame + stop codons cgtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagtctgagagccgaggacacggctgtatattactgtgtaagagtgggggccgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 17688 JY8QFUQ01CVX35 unproductive Homsap IGHV3-9*01 F 922 92.13 199/216 nt 90.74 196/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.37.11] CVKRSGNYR#NWFDIW out-of-frame - in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 191 to 191 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) ctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaAatgaacaatctgagAaaatgaggacacggcctgtattactgtgtaaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaacccctggtcaccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 17689 JY8QFUQ01AV3R5 unproductive (see comment) Homsap IGHV3-7*01 F 910 90.87 199/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [2.17.38.11] CAGGQRLA##DYW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 195 to 195 in the user submitted sequence), (cause frameshift); gcctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaGggggctcgagtgggtggCccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagcCcccgaggacacggctgtatatttctgtgcgggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaaggggcccatcggtcttcccccctggccgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaccggtgacggtgtcgtggaactcagg 17690 JY8QFUQ01BS2NT productive (see comment) Homsap IGHV3-66*02 F (see comment) 763 84.51 180/213 nt 84.04 179/213 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-21*01 F 3 8 7 11 8.7.11 [1.16.38.11] CARHLMVYALDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,51% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtgggaagtatatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttattagtactggcactgcatactacgcagactccgtgaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17691 JY8QFUQ01BFI2P productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLESVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagtccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 17692 JY8QFUQ01CGYG5 No results 17693 JY8QFUQ01CKFA2 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 700 84.54 164/194 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found Low V-REGION identity (84,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcg 17694 JY8QFUQ01AP042 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.16.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctgagtgggtctcaggtctcagtggtagtggtgatagcacatacactcaaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17695 JY8QFUQ01BH8GS unproductive (see comment) Homsap IGHV3-9*01 F 440 90.65 97/107 nt 89.72 96/107 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 16 8.X.16 [1.15.11.11] CAKDGSAIPVTGTYFEYW in-frame - stop codons in FR2-IMGT, from codon 54 of V-REGION: 109 nucleotides (from position 74 in the user submitted sequence), (cause frameshift) tctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggaatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17696 JY8QFUQ01CK3OJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1035 97.7 212/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + gtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17697 JY8QFUQ01B90TR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17698 JY8QFUQ01C5W8H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); agcctccgaattcatccttgacagttatgccatgagttgggtccgccaggCccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17699 JY8QFUQ01C0OJR productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 673 79.81 170/213 nt 78.87 168/213 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) tctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaAGggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17700 JY8QFUQ01A8BTW productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17701 JY8QFUQ01CJMO2 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.37.11] CAREKGSGPPN#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagcccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccaacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17702 JY8QFUQ01BQAXH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcccctttagcaactatgacatgaattgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggtttcttcccccag 17703 JY8QFUQ01CFF15 productive (see comment) Homsap IGHV4-4*07 F (see comment) 774 84.33 183/217 nt 83.41 181/217 nt Homsap IGHJ4*03 F 195 89.58 43/48 nt Homsap IGHD3-3*02 F 3 8 7 16 8.7.16 [2.17.38.11] CARSGYTSIVGVREFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'GATAAA' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift); tgtctctggCgggccccatgactGATAAAaattactattggagttggatccggcagcccgccgggaagggactggagtggctcggacgtgtttatggtagcgggagcacaagctccaatccctccgtcaggagtcggatcaccatgtcaatatacacgtctatgaaccaattctccctgaggttgagttctgtgaccgccgcggacacggccgtctattattgtgcgagatcaggttatacttccattgtcggagtgagggagtttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17704 JY8QFUQ01CEDV7 unknown (see comment) Homsap IGHV3-11*01 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17705 JY8QFUQ01APUXY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - cctctggattcaccttcagtacctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtatgaaccctgatggaagtactataagctacatggactccctgaagggccggctcaccatctccagagacaacgccaagaacacgttgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaaggggtggtttggagcccgtagattactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17706 JY8QFUQ01AJ9K5 productive Homsap IGHV3-74*03 F 914 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVDSDGWHGTIDRW in-frame + cctctggattcaccttcagtaattactggatgtactgggtccgccaagttccagggaaggggctggtgtgggtcgcccgtattaataacgatgggagtagcaaaacttacgcagactccgtgaggggccgattcaccatctccagagacaacgccaagaacacactgtttctgcaaatgaacagtctgagaggcgaggacacggcttcatattattgtgcaaaagtggatagcgatggctggcacggaacaatagaccgctggggccagggagtcctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17707 JY8QFUQ01ADHC7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccatggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17708 JY8QFUQ01CGOZX No results 17709 JY8QFUQ01BAGHH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17710 JY8QFUQ01DGD1O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 861 88.18 194/220 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKCKAPGKVDWFDPW in-frame - agcctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagcgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17711 JY8QFUQ01CFX3B productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + tctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtcaccgtctcctcaccatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17712 JY8QFUQ01B11DU productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - tttctggatacagttttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17713 JY8QFUQ01DISCP productive (see comment) Homsap IGHV4-61*02 F 849 87.0 194/223 nt 85.65 191/223 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [2.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 118 in the user submitted sequence), (cause frameshift) tgtcgtctggtgactGccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattAgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17714 JY8QFUQ01AKIRH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17715 JY8QFUQ01ASUWR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift); cgtctacattcgcctttagcaactatgccatgagctgggtccgccaggGCtccgagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17716 JY8QFUQ01AQ3RI No results 17717 JY8QFUQ01AKROJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 729 82.03 178/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARGGTDFDYW in-frame + Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttacatttagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgaggggccgcttcaccatctctagagacgacgccaagaattcactttatctgcagatgaacaacctgagaggcgaggacacggctgtctatttttgtgcgagaggggggactgattttgactattggggccagggaaccctggtcaccgtctcctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 17718 JY8QFUQ01B6SLF productive Homsap IGHV3-64*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + tctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17719 JY8QFUQ01BF98P No results 17720 JY8QFUQ01AQEWR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggGggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccCctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17721 JY8QFUQ01CL96A productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17722 JY8QFUQ01C2L83 No results 17723 JY8QFUQ01BU1G8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctccaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17724 JY8QFUQ01CQR6E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17725 JY8QFUQ01CE18D No results 17726 JY8QFUQ01CAKWX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 990 95.39 207/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + ctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17727 JY8QFUQ01BISKJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctggattcacctttaccaactgtggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtctccccctgcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17728 JY8QFUQ01CS5J5 unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcacctTttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17729 JY8QFUQ01AFKEB productive Homsap IGHV1-8*02 F 822 87.38 187/214 nt Homsap IGHJ2*01 F 193 84.91 45/53 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [0.17.38.11] CTTKFGSDWQSDWYFHVW in-frame + tggagacacattccccagccatgacatcaactgggtgcgacaggccactggagaagggcttgagtggatgggacggatgaaccctaagactggtgacacaagctttgcacagaagttccacgatagagtcaccatgatcagtgacacctccataagtacagtgtacatggagctgagtagcctgagatctgaagacacggccatttactattgtacgacaaaattcgggagtgactggcaatcggactggtacttccacgtctggggccgtggcacctcggtcaccgtctcctcagcatcccgaccagcccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 17730 JY8QFUQ01CXFN5 productive (see comment) Homsap IGHV3-72*01 F 1093 98.67 222/225 nt 98.22 221/225 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [2.17.38.11] CLRPPRYDPWG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaAaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctgggggccagggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17731 JY8QFUQ01AJ0TB No results 17732 JY8QFUQ01ALVXP No results 17733 JY8QFUQ01BPCFK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDRMIHTMRGAFDMW in-frame - ctctggattcaccttcagaaccaatgccatgaactgggtccgccaggctccagggaaggggctggagtggatctcagttattaatggtcccggtgatatcacatactacgcagactccgtgaagggccggttcaccatgtcccgagacaattccaaggacacgttgtatttgcaaatgatcagcctgagaggcgaggacacggccatatattactgtgcaaaagatcgtatgatacacacgatgaggggagcttttgatatgtggggccgagggacaatggtcaccgtctcttccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacggcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17734 JY8QFUQ01B02W0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17735 JY8QFUQ01AZEZ8 No results 17736 JY8QFUQ01DC610 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARRPSGSHWRLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'CC' (2 nucleotides at position 134 to 135 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'A' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); ggttctggatacagttttaccaacttctggatcggctgggtgcgccagatgcccggggatggcctgcagtggatggggatcatccatcctggtgactctgataccagatacagcccgtccttccaaggccaggCCtcaccatttcagtcgacaAagtccaccaacaccgcctacctgcagtggagcagcctgaaggcctcggacagcggcatctattattgtgcgagacggccgagtgggagtcattggagacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17737 JY8QFUQ01CHTSU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17738 JY8QFUQ01ADZAX No results 17739 JY8QFUQ01BEU17 productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17740 JY8QFUQ01B50HH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggcccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17741 JY8QFUQ01CIMV8 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*03 F or Homsap IGHV3-33*06 F (see comment) 373 64.56 133/206 nt 64.08 132/206 nt 8 7 X 8.7.X [1.17.34.X] null - No rearrangement found Low V-REGION identity (64,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17742 JY8QFUQ01BILUG unknown (see comment) Homsap IGHV3-11*01 F 943 93.9 200/213 nt 92.96 198/213 nt 8 7 X 8.7.X [1.17.37.X] null - No rearrangement found in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) ctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgagggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17743 JY8QFUQ01AP8B1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt 92.59 200/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggcgtggagtggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17744 JY8QFUQ01BGZB0 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17745 JY8QFUQ01CHAEJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaacctcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17746 JY8QFUQ01CIJU5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 886 90.28 195/216 nt 88.89 192/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); tctggatacagttttaacagttatgccatgacttggGgtccgccaggctccagggaaAggggctggagtgggtctcaactattagtggcactggtgGgtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17747 JY8QFUQ01BOYOR productive Homsap IGHV3-48*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + cgtctggattcacctttagtgattatgccttgaactgggtccgccaggctccaggaaaggggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17748 JY8QFUQ01B3VGR No results 17749 JY8QFUQ01DMR3X productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'TG' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift); gtttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccTGggggaagggactggagtctgtctctgctttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17750 JY8QFUQ01AHMDP productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame + gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17751 JY8QFUQ01AEMFS No results 17752 JY8QFUQ01BWS44 productive (see comment) Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt 81.11 176/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17753 JY8QFUQ01C6RK2 No results 17754 JY8QFUQ01A46X0 No results 17755 JY8QFUQ01C56PW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 17756 JY8QFUQ01B2QIV unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 435 76.67 115/150 nt 8 7 X 8.7.X [1.17.16.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B2QIV ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (76,67% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactacttccccgaaccggtgacggtgtcgtggaactcag 17757 JY8QFUQ01AZKV6 No results 17758 JY8QFUQ01COXAV productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaAactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17759 JY8QFUQ01BSS1N productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17760 JY8QFUQ01AMPZY productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*10 F or Homsap IGHV1-69*14 F 804 86.45 185/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*02 F 3 8 8 22 8.8.22 [0.17.38.11] CARGGKSPRRDIIQGVTVDALDLW in-frame + tggagacaccttcagtagccaagccatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggcgggatcatccctatttttgatatgacgaggtacccacagaggttcgagggcagaatcacgattaccgcggacacgtccacgaccacactttacatggaactgagcagcctgaggtctgaggacacggccgtgtatttttgtgcgagaggcgggaagagtcctcgtcgtgatattatacagggggtgactgttgatgctcttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17761 JY8QFUQ01CDYHQ productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcctcctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17762 JY8QFUQ01ASPTX No results 17763 JY8QFUQ01BGFCA productive (see comment) Homsap IGHV3-7*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [0.17.38.11] CARGTSVDPGIDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'GG' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift); tggattcacctttagtaattattggatgcactgggtccgccaggtttcaggggaGGggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17764 JY8QFUQ01BMHY7 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 951 92.73 204/220 nt 92.27 203/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 7 10 10 7.10.10 [0.17.38.11] CTHLREEMSYEW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) ctggagtcaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17765 JY8QFUQ01A045O unproductive Homsap IGHV3-48*01 F 1065 99.53 213/214 nt 99.07 212/214 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [0.16.38.11] CASNFWSGSPG##YYYGMDVW out-of-frame - in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtagctatagcatgaactgggtccgccaggctccaggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgaatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17766 JY8QFUQ01DGR8A productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17767 JY8QFUQ01C7FHX No results 17768 JY8QFUQ01B3Y86 unproductive Homsap IGHV3-11*01 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD2-21*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREYSSGEKGWF#PW out-of-frame - ctctggattcaccttcaatacctactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcacacattagtagtagtggcagtgtcacatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgagggcacggccctgtattattgtgcgagagaatacagtagtggtgaaaagggctggttcgaccctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 17769 JY8QFUQ01AOIG1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 95.19 198/208 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 6 8 15 6.8.15 [X.17.38.11] CARLCGNDCRNDVFDIW in-frame - caccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17770 JY8QFUQ01A006G productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattggggctggatccggcagGcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 17771 JY8QFUQ01B6WLI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17772 JY8QFUQ01CH00N unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17773 JY8QFUQ01DBLUE No results 17774 JY8QFUQ01BNROR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 833 87.16 190/218 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + cctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17775 JY8QFUQ01C7M5B productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 17776 JY8QFUQ01CF7L2 productive Homsap IGHV3-7*03 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccgccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17777 JY8QFUQ01B6GID productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17778 JY8QFUQ01CKQ1C productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 1002 96.73 207/214 nt Homsap IGHJ1*01 F 170 80.77 42/52 nt Homsap IGHD6-19*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARPDGGNGWAAKYFQMW in-frame - ctctgggttcaccgtcagtagcaactacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttatgtttagcggtggtggcacaaactacgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacactgtatcttcaaatgaacagcctgagagccgcggacacggccgtgtattactgtgcgagacctgacggaggcaatggctgggccgcaaagtactttcagatgtggggccagggcacccttctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17779 JY8QFUQ01CA6MQ productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17780 JY8QFUQ01AROW2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKEIAVSGEGALDFW in-frame + cctctggattcaccttcagtaactatagcatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctttcccca 17781 JY8QFUQ01BDWRF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccaggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17782 JY8QFUQ01DTB3E unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttaagtga 17783 JY8QFUQ01CQKI1 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccca 17784 JY8QFUQ01A4ILH productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggGggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17785 JY8QFUQ01CFZJT productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17786 JY8QFUQ01AROWV productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 728 82.33 177/215 nt 81.4 175/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 46 of V-REGION: 'CCAG' (4 nucleotides at position 53 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccCCAGgggaaggggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17787 JY8QFUQ01BGKA2 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 88.99 194/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD2-2*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARYCSSDSCQGYHDAFDVW in-frame - cttctggatacatcttcacgaaccactggatcggctgggtgcgccagatgccgggtagaggcctggagtggatggggatcatctatcctggtgactccgattccagatacggcccgtccgcccaaggccaggtcaccttctcagtcgacaagtccatcgccaccgcctaccttcagtggagtagcctgaaggcctcggataccgccacgtactactgcgcgagatattgtagtagtgacagctgccaagggtaccatgatgcttttgatgtctggggccaagggacaatggtctccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17788 JY8QFUQ01CSDQW productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17789 JY8QFUQ01C20A3 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt 85.59 190/222 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17790 JY8QFUQ01AH797 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcgatagttactacCtggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17791 JY8QFUQ01AQTMT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17792 JY8QFUQ01CUJHO No results 17793 JY8QFUQ01AC3NO No results 17794 JY8QFUQ01CEOCK productive (see comment) Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17795 JY8QFUQ01CO7NK No results 17796 JY8QFUQ01BIGED productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFHYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttcactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17797 JY8QFUQ01BALQI unproductive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcccgccctgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactc 17798 JY8QFUQ01CTLV7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17799 JY8QFUQ01B7OCB unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt 8 7 X 8.7.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtggctGccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtncgagactgggggccccggttcgggggactactatggggccagggaaccctgggtcaccnnctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17800 JY8QFUQ01BDW1A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17801 JY8QFUQ01CETVH unproductive Homsap IGHV3-72*01 F 1078 98.65 219/222 nt 98.2 218/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.16.38.11] CLRPPRYD#PG out-of-frame + in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17802 JY8QFUQ01BF5Z7 unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-71*03 P or Homsap IGHV3-72*01 F 283 88.73 63/71 nt 8 X X 8.X.X [1.14.X.X] null + No rearrangement found ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtggg 17803 JY8QFUQ01BFNMT unknown (see comment) Homsap IGHV3-7*01 F 1031 96.79 211/218 nt 95.41 208/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); cctctggattcaggtttagGcatctattggatgagctgggtGccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgTtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17804 JY8QFUQ01C08HE unproductive Homsap IGHV4-61*02 F 1005 95.45 210/220 nt 95.0 209/220 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGSTYYYDTSAYYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtggtagttTtctactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtgtctatgccagtggaaccaccaagttcaacccctccctcaagagtcgagtcactttatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgcggggttcgacatattactatgatactagtgcttattactactttgactactggggcccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17805 JY8QFUQ01BH4MR productive Homsap IGHV3-7*03 F 846 88.02 191/217 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17806 JY8QFUQ01BUNFI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17807 JY8QFUQ01A8JZF productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 17808 JY8QFUQ01CD41O productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F 894 91.12 195/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD5-18*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAIVDTNLVSATGKDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacaccttcagcaactactatagacactgggtgcgacaggcccctggacaagggcttgagtggatgggaatgatcaaccctagtagtgattacaaatattacgcacagaaatttcagggcagagtcaccatgaccagggacacgtccacgagcacagtcttcatggagctgagtagcctgagatctgacgacacggccgtgtattattgtgcaatagtggacacaaatttggtttcggcgaccggtaaagactcctggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 17809 JY8QFUQ01BTS0O productive Homsap IGHV3-23*05 F (see comment) 439 81.82 108/132 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 6 16 X.6.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (81,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17810 JY8QFUQ01C9F9A unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in FR2-IMGT at codon 50 of V-REGION: 'T' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctTggagtgggtctcagttattagtggaagtggtgataccacatcgtacgCcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17811 JY8QFUQ01CS2FP No results 17812 JY8QFUQ01CARZ1 productive Homsap IGHV4-39*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17813 JY8QFUQ01DSA7F unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17814 JY8QFUQ01A4LRG productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggcatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17815 JY8QFUQ01DC9BI No results 17816 JY8QFUQ01AM2GA unproductive (see comment) Homsap IGHV3-74*03 F (see comment) 707 80.73 176/218 nt 79.36 173/218 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRGNHWLEGG*LL# out-of-frame - stop codons Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); cctctggaGttcaacgtcagtggatactggatgcactgggtccgccaagtgccagggaaggggctggtatGgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacgGgctgtatacttttgtgtgagggggaaccactggctggaggggggttgactactgggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 17817 JY8QFUQ01AWTW0 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17818 JY8QFUQ01AM8JL productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17819 JY8QFUQ01BWE2P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagtacacactacgcggaccccgtgcagggccggttcatcatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17820 JY8QFUQ01CNBQ8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17821 JY8QFUQ01BP7D4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD2-8*02 F 2 8 8 24 8.8.24 [1.17.38.11] CVRAAGYCPGGDDCYKIGTHDSLDIW in-frame - gtctggattcaccttcagtacctatggcacacattgggtccgccaggctccaggcaaggggctggactgggtggcagttagttggcatgatggaagtcaggaatattatgcagactccgtgaggggccgattcactgtctccagagacaattccaagaacacggcatatctgcatatgaatgtcctgagaggcgaagacacggctgtctactactgtgtgagagcggcggggtactgtcctggtggtgatgactgctacaagatcggaactcatgactcccttgatatctggggccgaggggcagttgtctccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17822 JY8QFUQ01AZRKU productive (see comment) Homsap IGHV3-7*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 7 8 8 7.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctccggattcattttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17823 JY8QFUQ01AZYDF productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDLSTSGFDAIDIW in-frame + ctctggattcaccttcaatctctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctcatatgatggaaataataaatactatgcagactccgtgaagggccgattcatcatctccagagacaactccaagaatctgctatatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaaagatttgagtactagtggctttgatgctattgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17824 JY8QFUQ01AVLNX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 806 85.78 187/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaagccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 17825 JY8QFUQ01B7XTY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaacctcaatacctttggcatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17826 JY8QFUQ01A6DZT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 77 of V-REGION: 'G' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcGaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17827 JY8QFUQ01A1PBD productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*06 F 919 91.32 200/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKDKGLRYFDYW in-frame - gcgtctggaatcaccttcagtgcctctggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcttttataaggtctgatggaagcgatgaatactttgcagactccgtgaagggccgattcagcatctccagagacaattcgaagaacacggtgtatctccaaatgaacaccctgagagccgaggacacggctatgtattactgtgcgaaagataaggggctacgatactttgattattggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17828 JY8QFUQ01AHNBF productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17829 JY8QFUQ01CBMG4 No results 17830 JY8QFUQ01BHPA3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 92 52.31 68/130 nt 8 8 X 8.8.X [1.17.9.X] null + No rearrangement found stop codons ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 17831 JY8QFUQ01AW9GE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRWSGTYPFASW in-frame + Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagtcccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggctttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttcccccgtggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 17832 JY8QFUQ01AL21Q productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDPSGSGWAFESW in-frame + cgtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17833 JY8QFUQ01BXFGU No results 17834 JY8QFUQ01CZMSL No results 17835 JY8QFUQ01AQ6RF productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaggaactatgctatgcactgGggtccgccaggctcctggcaaggGggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaaccgtggtccgtcgcatgcctggtccagggcttcttcccc 17836 JY8QFUQ01CJ5H7 productive Homsap IGHV3-9*01 F (see comment) 759 84.11 180/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [0.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17837 JY8QFUQ01AGZ50 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDREDSSGYYFFRDGFDIW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagatcgtgaagatagtagtggttattacttcttccgtgatggttttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17838 JY8QFUQ01ASHYE productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17839 JY8QFUQ01DMUBJ productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17840 JY8QFUQ01DQ53C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17841 JY8QFUQ01CMFGZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 96.65 202/209 nt 96.17 201/209 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQIDYGDFSRHGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); acaactttaccggctactggatcggctgggtgcgccagcggcCccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccatccttccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaaatagactacggtgacttctctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17842 JY8QFUQ01CNALN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17843 JY8QFUQ01B36L3 unproductive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-3*01 F 1 8 10 X 8.10.X [1.17.38.11] CITSFGGRSLAY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17844 JY8QFUQ01B7BKW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17845 JY8QFUQ01CDIVK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagGggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17846 JY8QFUQ01C1QI4 productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt 99.11 222/224 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); cttctggattcacctttggGtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaAaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17847 JY8QFUQ01BTJZQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagGggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17848 JY8QFUQ01BKNNZ No results 17849 JY8QFUQ01CJKHK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + ctctggattcacctttggcagccaagccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17850 JY8QFUQ01A02XZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgggtgtcgtggaactc 17851 JY8QFUQ01BM1C9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatcCcataagtagtgGgtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17852 JY8QFUQ01DR9LO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + cctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17853 JY8QFUQ01BP3M1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 17854 JY8QFUQ01DAPX2 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKEEFDTGWTQPGDW in-frame + cctctggattcatcttcagtgactatggcatgcactgggtccgccaggctccaggcgaggggctggattgggtggcatttatacgatatgatggaaatgagatacactatccagactccgtgaggggccgattcaccatctccagagacaattccaagaacaccctatatctagaaatgaacaatgtgagacctgaggacacggctgtgtattactgtgcgaaggaggaatttgacactggctggacacaaccgggcgactggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17855 JY8QFUQ01B8YQQ productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17856 JY8QFUQ01CB1GG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17857 JY8QFUQ01CS72X No results 17858 JY8QFUQ01CHUJH No results 17859 JY8QFUQ01AL2CW productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt 99.55 223/224 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgAaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17860 JY8QFUQ01CNK50 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1048 96.44 217/225 nt 96.0 216/225 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CARGSSRGGRSDVNYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 17861 JY8QFUQ01B3TI8 productive (see comment) Homsap IGHV3-7*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [0.17.38.11] CARGTSVDPGIDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggattcacctttagtaattattggatgcactgggtccgccaggtttcagggaGgggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17862 JY8QFUQ01BQ7U8 No results 17863 JY8QFUQ01AVZKB productive Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-8*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRGRTNSPVDLW in-frame + Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagaggtagggggcgcactaatagtccagttgacctctggggccagggaacccaggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccccag 17864 JY8QFUQ01DKN2O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 780 84.09 185/220 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [2.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame - Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) agcctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 17865 JY8QFUQ01BVFET productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - agcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17866 JY8QFUQ01ASA07 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17867 JY8QFUQ01B8EMT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17868 JY8QFUQ01C8GT7 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 846 88.02 191/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMFYYGMDVW in-frame - atctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17869 JY8QFUQ01BP9BO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17870 JY8QFUQ01C2XTT unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 120 53.9 76/141 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17871 JY8QFUQ01ARQLK unproductive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGDDVGTIIGE##DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacAaaaattttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagagggggggacgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17872 JY8QFUQ01B4YIL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacgttccccgaaccggtgacggtgtgcgtggactca 17873 JY8QFUQ01BHXQZ unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 17874 JY8QFUQ01CDG0F productive (see comment) Homsap IGHV3-48*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARDMIIFGGALDNW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcaggtttagcatctattggatgagctgggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgggagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17875 JY8QFUQ01CZKAD productive (see comment) Homsap IGHV4-39*03 F 915 90.87 199/219 nt 89.95 197/219 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); ctccggtggctccatcaacagtagaaattattattgGgggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactGacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtttaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17876 JY8QFUQ01CNTRA productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-13*01 F 1 10 7 18 10.7.18 [1.17.38.11] CARDRYVVDRSWYGNFFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtggtacttactactggagctggatccggcagcccgccgggaaggcactggaatggattggacatatctctaccagtgggagtaccacctacaaccCcctccctcaagagtcgagtcaccatatcagctgacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcagacacggccgtgtattattgtgcgagagatcgatatgtcgtggacaggagctggtacggcaactttttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccg 17877 JY8QFUQ01A91KA No results 17878 JY8QFUQ01C7T2H productive (see comment) Homsap IGHV3-11*01 F 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17879 JY8QFUQ01CBQC2 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17880 JY8QFUQ01B5UZM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 194 56.98 98/172 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggattcaccttcagtagctatactatgaactgggtccgccaggctccagggaaggggctggagtacgtctcatccattagtagcaatggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17881 JY8QFUQ01DB5ES productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1023 96.36 212/220 nt 95.45 210/220 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.16.38.11] CARDTLEVVSNMDDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cagcctctggattcaccGttcagtcgttatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17882 JY8QFUQ01CA8RY No results 17883 JY8QFUQ01CC5S0 productive (see comment) Homsap IGHV4-61*02 F (see comment) 740 81.9 181/221 nt 81.45 180/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERSISIGGAREFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tcactggtggccccatgggcagtagtttatacttctggaattgggtccgacagcccgccgggaagagactggagtggatcggAcgtggtttatgatgatgggagtacccgctacaatccctccctcaggggtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaggttgagttttgtgaccgccgcagacacggcccgttattactgtgcgagagaacggagtatttcgattggcggagcgagagaatttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17884 JY8QFUQ01BX1Z6 unproductive (see comment) Homsap IGHV3-48*01 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.16.38.11] CARASTFYYDGSGYRDA#FDIW out-of-frame - stop codons in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) agtctctggcttcagtttgagtacttataccatgaactggtccgccaggctccaggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgctttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17885 JY8QFUQ01BJXZO productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.37.11] CARGFSAWGQDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctattctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17886 JY8QFUQ01AQQXF No results 17887 JY8QFUQ01BYI4A unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ5*01 F 111 68.63 35/51 nt 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccaggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17888 JY8QFUQ01AQAL7 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17889 JY8QFUQ01AR91V productive (see comment) Homsap IGHV4-61*02 F (see comment) 779 84.4 184/218 nt 83.03 181/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 9 7 13 9.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'CTT' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) tctctggtgcctccatcactagtggtaCTTactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactgggagcacctattacaaTcccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17890 JY8QFUQ01AV9KO unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.16.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17891 JY8QFUQ01CU257 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRWSGTYPFASW in-frame + Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagtcccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggctttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17892 JY8QFUQ01A0TNI productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17893 JY8QFUQ01B93OB productive Homsap IGHV3-21*04 F, or Homsap IGHV3-23*01 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 17894 JY8QFUQ01A18L5 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame + tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 17895 JY8QFUQ01BUZXB No results 17896 JY8QFUQ01A4H9C productive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDHIWAFDFW in-frame + cctctggattcaccttcagtgactatagcatgaactgggtccgccagactccagggaagggggtggagtggatttcatacatcggccgtggtggtgatgggatatactacgcagactctgtgaagggccgaatcaccatctccagagacaatgccaagaactcactttttctgcaaatgaacaccctgagagacgacgacacggctgtgtattactgtgcgagagaccacatttgggcttttgatttctggggccaagggacaaaggttaccgtctcgtcagcatcccccgaccagccccaaggtcttcccgctgagcctcgaagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17897 JY8QFUQ01C4I62 productive (see comment) Homsap IGHV3-48*02 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRYSYAHGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctccggattcacctccatctcctatggcatgcactgggtccgccagattccaggaaaggGggctggagtcggttgcatacattagtgatagtaatagcagcatatactatgcagactctgtgaagggccgattcaccatctcccgagacaaagacaagaagtcagtatatctgcaaatgagcagcctgagagacgaggacacggctatttattactgtgcgagggggcgatacagttatgctcacggaatggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17898 JY8QFUQ01ATCVI productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1020 95.52 213/223 nt 95.07 212/223 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CARHEGTPVSDVGGYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggaatgggttggccgtattagaagcagagcttacagttccgcgacagcatatgcagcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggtgtatctgcaaatgaacagtttgaaaaccgaggacacggccgtgtattactgtgctagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggccaagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17899 JY8QFUQ01CZ3YD unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt 89.29 200/224 nt Homsap IGHJ6*02 F 157 72.58 45/62 nt Homsap IGHD4-11*01 ORF 3 8 10 X 8.10.X [1.17.38.11] CHYSPKRNLCNG#YFAMDVW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 189 to 189 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'AC' (2 nucleotides at position 202 to 203 in the user submitted sequence), (cause frameshift); cctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaagGgggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgcCccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaAacagcctgaaaaACccgaggacacagccgtgtattactgtcactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtcgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttcccccgcaaccggtgacggtgtcgtggaaactca 17900 JY8QFUQ01B85V0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 929 91.4 202/221 nt 90.05 199/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARSYGFSRFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccagtagtctttaccgctGggggctggatccgccagtccccagggGAaagggcctggagtggatagggaatatcttttatggtgggaccaCcctactacaacccgtccctcaagagtcgagtcaccttatccatagacacgtccaagagccagttctccctgaagctgtcctctgtgaccgccgcagacacggctctatattactgtgcgagatcgtacggtttctctcggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17901 JY8QFUQ01CLNWZ unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 617 94.85 129/136 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcacc 17902 JY8QFUQ01AZNQP productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); gcctctggattcaccttGcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcatccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 17903 JY8QFUQ01BLQ3C productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame + cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccag 17904 JY8QFUQ01BRSG2 unknown (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 135 52.02 103/198 nt 8 6 X 8.6.X [1.17.33.X] null - No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagccctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 17905 JY8QFUQ01CQPHJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctcgagcctccaccaagggcccatcggtcttcccccatggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17906 JY8QFUQ01AKVNJ productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.37.11] CAKSPSQVGYYLDCW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 136 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtacctttggcatgcactgggtccgccaggctcccggcaaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcacatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17907 JY8QFUQ01CAEZS unproductive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY## out-of-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactgggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17908 JY8QFUQ01CLCEW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca 17909 JY8QFUQ01CH51T No results 17910 JY8QFUQ01C5K3P No results 17911 JY8QFUQ01AFRC4 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17912 JY8QFUQ01AWV4P No results 17913 JY8QFUQ01A8412 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17914 JY8QFUQ01CQH14 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctctaagagcacctctgggggccaccagcggccctgggctgcctggtcaaggactcttccccggaaccggtgacggtgtcgtggaactcagg 17915 JY8QFUQ01AC8KF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17916 JY8QFUQ01DDNDA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17917 JY8QFUQ01DJQ7I productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 176 86.96 40/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame + cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcccagggctnttcccc 17918 JY8QFUQ01DDEDC productive Homsap IGHV3-9*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame + cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17919 JY8QFUQ01DEFNK No results 17920 JY8QFUQ01CSO9O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17921 JY8QFUQ01CL0GK No results 17922 JY8QFUQ01BSXFG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARGVGATAEYFQYW in-frame + ctctggattcacctttagtaactatgccatgacctggattcgccaggctccagggaaggggctagagtgggtctcagttattagtggaagtggtggtactacatactacgcagactccgtgaagggccggttcaccatctccagagacaatcccaagaacacgctgtatttgcaaatgactagcctgagagtcgaggacacggccatatatttctgtgcgaggggagtgggggctaccgctgaatactttcaatactggggccagggcgccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17923 JY8QFUQ01CP3FT unproductive (see comment) Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDLRRP##GMDVW out-of-frame + stop codons ctctggattcacctttgatgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtattagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcatcacatccagagacaatgccaagaactccatctatttgcaaatgaacagtctgagagatgacgacacggccttctacttctgtgcaaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccaaatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 17924 JY8QFUQ01DA6WQ productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [2.17.38.11] CTRGRSDAWELSDHW in-frame - cgtcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 17925 JY8QFUQ01CPWZG productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccTggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17926 JY8QFUQ01DBZJH productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 17927 JY8QFUQ01CH3WR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17928 JY8QFUQ01A7KV1 productive Homsap IGHV3-74*03 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17929 JY8QFUQ01AD2DE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYYYDNIPAHDTFDLW in-frame - ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacattgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaagaagtactactatgataatattcctgcgcatgatacctttgatctctggggccaagggacaatggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17930 JY8QFUQ01A55FP productive Homsap IGHV3-7*01 F 1014 95.91 211/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - aggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 17931 JY8QFUQ01CLFHV unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDNYGDY## out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17932 JY8QFUQ01BH53J No results 17933 JY8QFUQ01B3MWL unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 945 93.09 202/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDV* in-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctgaggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 17934 JY8QFUQ01CP16Y unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [2.17.38.11] CARVGTFNWFG#PG out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ggcctctggattcaGattttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtGcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctgggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17935 JY8QFUQ01BYDVO productive (see comment) Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ6*02 F (see comment) 220 83.87 52/62 nt Homsap IGHD1-26*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARYRGSYYDYGGVDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 147 to 147 in the user submitted sequence), (cause frameshift); cctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccaggGgacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctggggccgtggcacctcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 17936 JY8QFUQ01DCEKZ No results 17937 JY8QFUQ01DHIOD unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17938 JY8QFUQ01CCHKG productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttgcccccag 17939 JY8QFUQ01DLPO2 productive Homsap IGHV3-9*01 F 866 88.24 195/221 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDVTSESHFFALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) agccgtcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17940 JY8QFUQ01AKJVX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1007 96.74 208/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17941 JY8QFUQ01B8IZ5 productive Homsap IGHV3-48*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17942 JY8QFUQ01B6KRJ unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17943 JY8QFUQ01B2KOT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame - cctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17944 JY8QFUQ01CWAUA productive Homsap IGHV3-7*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - ctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17945 JY8QFUQ01B85C7 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17946 JY8QFUQ01BKM45 productive Homsap IGHV1-24*01 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame + cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 17947 JY8QFUQ01C270K unproductive (see comment) Homsap IGHV4-61*02 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 10 7 X 10.7.X [2.17.38.11] CATVARLG#AFDIW out-of-frame - stop codons in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 194 to 194 in the user submitted sequence), (cause frameshift); gtctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaGcccccgcagacacggccgtttattactgtgcgacagtggcgcgcctggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17948 JY8QFUQ01BWLVB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + cctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcagg 17949 JY8QFUQ01B4CN9 productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggttttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17950 JY8QFUQ01A9MZY productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17951 JY8QFUQ01CM4HO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17952 JY8QFUQ01CIL71 productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 17953 JY8QFUQ01C64G5 unknown (see comment) Homsap IGHV3-7*03 F 832 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaTggtttagtaactattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggtagtgagacttactatgtggaatctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17954 JY8QFUQ01C9V0T unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 882 89.4 194/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggccctgccgctggccttcacacagaagaccatcgaccgcttggcgggt 17955 JY8QFUQ01A2WHC productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcaccatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 17956 JY8QFUQ01BN73N No results 17957 JY8QFUQ01C9XLQ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD1-1*01 F 1 10 7 14 10.7.14 [1.17.38.11] CARELGNTERGIVDPW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcgacactagttatcactgggcctggatgcgccagcccccagggaagggcctggagtggattgctaatgttcattatactggcagcgcccactacaacccgtccctcaagagtcgagtcaccatactagtagacacgtcccagaatcagttctccctgatgctgagttctgtgaccgccacagacacggctgtgtattactgtgcgagggaacttggtaatactgagaggggaatcgtcgacccctggggccagggaatcccggtcagcgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17958 JY8QFUQ01DJNA6 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 820 86.3 189/219 nt 84.47 185/219 nt Homsap IGHJ6*02 F 187 79.66 47/59 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARRDSDFRMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 216 to 216 in the user submitted sequence), (cause frameshift); gtgtctggatatgactttagcagAattttggatcgcctgggtgcgccagatgcccgggaAaaggcctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctacttTtttagcagtctgagggcctcggacaccgccatgtaCtttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggaccacggtcaccgtgtctccaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17959 JY8QFUQ01CIRQ5 No results 17960 JY8QFUQ01BYE1J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt 8 8 X 8.8.X [1.17.38.11] CAKLGVAATTWNFFDY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaattgggggtggcagctactacttggaacttctttgactactggggagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17961 JY8QFUQ01DLFDG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [2.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); gtttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacgGgccttatattactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17962 JY8QFUQ01B9EY0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17963 JY8QFUQ01AK37R No results 17964 JY8QFUQ01BI4OT unknown (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 615 96.21 127/132 nt 94.7 125/132 nt 8 8 X 8.8.X [0.17.10.X] null + No rearrangement found in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactaTtttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcac 17965 JY8QFUQ01B5UDN unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [2.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctgggttgaGccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17966 JY8QFUQ01BCQZG productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17967 JY8QFUQ01BX2MX productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17968 JY8QFUQ01CNS8U productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 795 85.51 183/214 nt 85.05 182/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [0.17.38.11] CVRVRDYEIGGDFW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); tggaggcgccttcagcacctttcatatcacctgggtgcgacaggcccctggacaagggcttgtctggctggggaatatcattcctaCtttttggaacagtcgactacgcacgggggttccagggcagagtcacgattaccgcggacgaatccaccaacacagcctacatggagttgagcagcctgacatctgaggactcagccgtctatttctgcgtgagagttcgtgactatgaaattggtggtgacttctggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17969 JY8QFUQ01CHOJJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17970 JY8QFUQ01BUCUZ unproductive Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 99.54 218/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17971 JY8QFUQ01B7ROZ productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgctggtcccagggcttgcttccccca 17972 JY8QFUQ01BTU9P productive Homsap IGHV3-64*02 F 917 92.09 198/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVTCGDYSYEYW in-frame - ctggattcgcctttagtggctattggatgagttgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17973 JY8QFUQ01CO6O1 No results 17974 JY8QFUQ01CNDXZ productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag 17975 JY8QFUQ01CG1SW unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVREGRGTAAYGLDV## out-of-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctgggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggcagcacctccgagagcaccagccgccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17976 JY8QFUQ01CAXLD productive (see comment) Homsap IGHV3-66*02 F 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 2 8 7 17 8.7.17 [1.17.38.11] CSTPTYCRGGSCSQIFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtaactaccacatgGaggtgggtccgccaggctccagggaaggggctggagtgggtctcagttatttacagcggtggtagtacatattacatagactccgtgaagggccgattcaccatctcgagagacgattccgagaacacagtgtatcttcaaatgaagagcctgagagctgaggacacggctgtatattactgttcgacgcccacatattgtaggggcggtagctgttcccagatttttgactattggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17977 JY8QFUQ01CN9M7 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 926 92.56 199/215 nt 92.09 198/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctggattcacctttggttattatggcatgagctgggtccgccaagctccggggaggggcgtggagtgggtctctgtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 17978 JY8QFUQ01ASQT0 productive Homsap IGHV3-7*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 8 22 8.8.22 [1.17.38.11] CVRVRWPQYSNTWYGANQDVFDIW in-frame + ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccgtctccagagacaactccaagaattcactgtatctccaaatgaacagcctgagagtcgaggacacggctatttattactgtgtgagagtccgctggccccagtacagtaacacctggtacggggccaatcaggatgtttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17979 JY8QFUQ01BYLXC unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 600 82.76 144/174 nt 82.18 143/174 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (82,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggGggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgc 17980 JY8QFUQ01BE0MA No results 17981 JY8QFUQ01AKM0W productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 904 91.2 197/216 nt Homsap IGHJ4*03 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAREWAASHFDHW in-frame + gctggattcaccttcagtggctttgctttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17982 JY8QFUQ01B6RL8 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame - stop codons in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggagggggActggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17983 JY8QFUQ01CS8O3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 3 8 7 12 8.7.12 [2.17.38.11] CARWRSRSYDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcacctttagcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattacaagtggtggtagcacatactacgcaaactccgtgaagggccggttcaccgtctccagagacagttccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagatggcgtagtcggagctacgactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17984 JY8QFUQ01AKQ1X productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca 17985 JY8QFUQ01AHMI8 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17986 JY8QFUQ01B4BRQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcggggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17987 JY8QFUQ01CCMUH productive (see comment) Homsap IGHV3-11*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccaggGgacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17988 JY8QFUQ01B7TE7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctctggattcagatttagcagctatggcatgagctgggtccgccaggctccaaaaaaggggctggagtgggtctcaggaattagtgcgaatggtggtagtataaattatgcagactccgtgaagggccgattcatcatctccagagacaattccaagaacacattgtttctgcaaatgaatagcctgagagccgaagacacggccgtatattattgtgcgaaagagatagcagtgagtggtgaggggcgtgacttctggccaggaacctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17989 JY8QFUQ01BFG6Q productive Homsap IGHV4-61*02 F (see comment) 596 74.66 165/221 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARECSNSKVGPRALDSW in-frame + Low V-REGION identity (74,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tttctggtggcccgatcaaaagtcctgattaccattggacgtggatccggcagcccgccgggaagggactggagtgggtcggacgtgtctatatgactggttatgtcgaccacaatccatccctctccgggcgtctcaccatgtctatcgacacctcgaagaatcaattttctatgacattgacctctgtgaccgccgcagacacggccctatatttttgtgcgagggagtgtagtaattcgaaggtcggaccgagagcgcttgattcctggggcccgggaagtctggtcaccgtatcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17990 JY8QFUQ01DJMUZ productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17991 JY8QFUQ01CZPRJ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 807 85.45 188/220 nt 85.0 187/220 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); agcctctgaattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 17992 JY8QFUQ01BSUXU productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaAaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17993 JY8QFUQ01C1RKP No results 17994 JY8QFUQ01BDM2X unknown (see comment) Homsap IGHV3-74*03 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 17995 JY8QFUQ01A8YO2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKEMIRYGDDVFGGLNVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctgcagtgggtctctggtattagtggtggtggtgatgacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtgtattactgtgcgaaagaaatgatccgctacggggacgacgtttttggcggtctgaacgtctggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 17996 JY8QFUQ01C7CT3 productive (see comment) Homsap IGHV3-30*01 F 864 88.94 193/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagAaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 17997 JY8QFUQ01DS3DP unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*03 F 733 87.77 165/188 nt 87.23 164/188 nt 8 8 X 8.8.X [1.17.28.X] null + No rearrangement found in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttCctgcaaatggacagtctga 17998 JY8QFUQ01DD91R productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 103 62.9 39/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 17999 JY8QFUQ01DJSA7 productive Homsap IGHV4-30-2*02 F, or Homsap IGHV4-55*06 P or Homsap IGHV4-59*01 F or Homsap IGHV4-59*02 F or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F or Homsap IGHV4-59*09 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*07 F or Homsap IGHV4-61*08 F 162 94.59 35/37 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 X X 12 X.X.12 [X.X.12.11] CARAPGWMNPFDFW in-frame - ctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18000 JY8QFUQ01AFK3U productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18001 JY8QFUQ01CL67W productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 741 83.18 178/214 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CL67W ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18002 JY8QFUQ01BMS5S productive Homsap IGHV3-7*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYHYDMFGDYW in-frame + cctctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgttcggcgactactggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 18003 JY8QFUQ01CBDJS productive (see comment) Homsap IGHV1-3*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaggGcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18004 JY8QFUQ01AA0DL productive Homsap IGHV3-30*15 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [1.17.38.11] CARDELPWDTIEYYFDYW in-frame - ctctggattcacctttagtagatattccatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaatgagtagcctgagacctgaggacacggctgtgtattactgtgcgagagatgagctgccttgggatacaatagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 18005 JY8QFUQ01DFPZY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18006 JY8QFUQ01C17HE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggaggggcgtggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaGggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18007 JY8QFUQ01CDL1J productive (see comment) Homsap IGHV3-7*01 F 913 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); ctctggatttacttttaacaactattggatgacctgggttcgccaggntccagggaaggggctggaatgggtggccaacataaGaacaacatggaggtgaaacgtactatgCtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18008 JY8QFUQ01BPBJ6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*02 F 3 8 8 13 8.8.13 [1.17.38.11] CARTRGATDANFEYW in-frame - gtggtggatacaccttttccaattactggatccactgggtgcgccagatgcccgggaaaggcctggagtggttggggatcatctatcctggtgactctgataccagatatagcccgtccttccaaggccaggtcaccctctcagccgacaggtccatcagtaccgcctacttgcagtggagcagcctgagggcctcggacaccgccgtgtattactgtgcgagaacgaggggagctaccgacgcaaactttgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18009 JY8QFUQ01BVBI3 productive (see comment) Homsap IGHV3-11*01 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [2.17.38.11] CARDLVGSIGSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); agcctctggattcacatttggtgactacgtcatgacttggatccgccaggGctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18010 JY8QFUQ01CX6UO productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18011 JY8QFUQ01CZJAC unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F or Homsap IGHV3-74*01 F or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 117 80.56 29/36 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found cctctggattcacctctcctagatactggatgaatt 18012 JY8QFUQ01CZ1IL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 1 8 8 14 8.8.14 [1.17.38.11] CAKVGLMSARDRIDYW in-frame + ctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtggggctgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18013 JY8QFUQ01AG9DV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18014 JY8QFUQ01AE5OU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18015 JY8QFUQ01BG4L2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 18016 JY8QFUQ01CDLHG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGVIAVAG#DFDCW out-of-frame + cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggttatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaantcaggcgccctgaccagcggc 18017 JY8QFUQ01CKL3J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18018 JY8QFUQ01ADTQJ productive Homsap IGHV3-7*01 F 887 89.45 195/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18019 JY8QFUQ01BLJIG productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + gtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 18020 JY8QFUQ01BOAOM unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKGG*GYRYGSVFLPA##W out-of-frame + stop codons ctctggattcacctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagtaattggtggtgatggtggtagtccatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaggggggtagggatacaggtatggttcggtattccttcccgcttgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18021 JY8QFUQ01CVSYJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18022 JY8QFUQ01AL8VS productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 800 86.05 185/215 nt 85.58 184/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARADYYDTSAYYLDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 60 of V-REGION: 9 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggggtacagcttgcgaggctctgttttgcactgggtccgccaggcttccgggaaaggactggagtgggttggccgtgtcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggcttatctggaaatgaacagcctgaaaaccgaggacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctggggccaggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18023 JY8QFUQ01B7T0P productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 18024 JY8QFUQ01AVP58 No results 18025 JY8QFUQ01A6QQA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcaattttagttcttatggcatgaactgggtccgccaggctccagGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18026 JY8QFUQ01DCYQV No results 18027 JY8QFUQ01C3DIR No results 18028 JY8QFUQ01B75LI productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18029 JY8QFUQ01AI9PP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-16*02 F 2 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLADDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtctctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggctgatgactactttgactactggggccagggaatctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18030 JY8QFUQ01B2TLZ productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18031 JY8QFUQ01AV2PR unproductive (see comment) Homsap IGHV3-15*04 F 979 93.69 208/222 nt 93.24 207/222 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 10 X 8.10.X [1.16.38.11] CTHDAPYFLGER#FDYW out-of-frame + stop codons in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattccctttcagcaacacctacatgagctgggtccgccaggctccagggaaggggctggagtggttggccgtattgaaagcaaaactgatggtgggacaatagaatacgctgcacccgtgaaaggcagattaaccatatcaagagacgattcaaaaaacacgctgtatctgcatatgagcagcctgaagatcgaggacacagccgtgtattactgtacccacgatgccccgtactttttgggggagcgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 18032 JY8QFUQ01BBU4B No results 18033 JY8QFUQ01ARMZL No results 18034 JY8QFUQ01CIM0J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 585 92.65 126/136 nt 91.91 125/136 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 8 X 16 8.X.16 [1.1.35.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 81 nucleotides (from position 32 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcatcagttatggcatgaactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18035 JY8QFUQ01CX3GT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18036 JY8QFUQ01C0985 productive (see comment) Homsap IGHV4-4*07 F 1061 99.53 214/215 nt 98.14 211/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtttctacCtggagctggatccggcagcccgGccgggaagggactggagtggattAgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18037 JY8QFUQ01BNJF8 unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGVVTA#LDYW out-of-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 18038 JY8QFUQ01BKSGU productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18039 JY8QFUQ01DGJPK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 933 91.82 202/220 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + ctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18040 JY8QFUQ01BFC1J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQNWFD#PG out-of-frame - ctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18041 JY8QFUQ01ATQKU No results 18042 JY8QFUQ01CPNM5 unproductive Homsap IGHV3-30*01 F 909 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREWAASHFDH## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); cgctggattcaccttcagtggctttgctttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacgGgctgtatattactgtgcgagagagtgggcagccagtcactttgaccactggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18043 JY8QFUQ01BVL4F productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 18044 JY8QFUQ01BZ1MY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18045 JY8QFUQ01B3ID0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatctccagagacaacgccaggaactcattgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18046 JY8QFUQ01CAYJB unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 18047 JY8QFUQ01CGGE1 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 272 62.65 104/166 nt 8 10 X 8.10.X [1.17.20.X] null + No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (10 AA in JY8QFUQ01CGGE1 ; 8 AA in Homsap_IGHV3-7*01), and low V-REGION identity (62,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcactttcactaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtggattggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18048 JY8QFUQ01B09TL unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ2*01 F (see comment) 76 60.38 32/53 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18049 JY8QFUQ01ARLW2 unproductive Homsap IGHV3-72*01 F 1079 98.21 220/224 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagggatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18050 JY8QFUQ01BT4IW No results 18051 JY8QFUQ01CRNO7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctagagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18052 JY8QFUQ01A56UP productive Homsap IGHV4-61*02 F 897 90.0 198/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + ctctggtggccccatcagcagtggtacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18053 JY8QFUQ01B1G7S productive (see comment) Homsap IGHV3-9*01 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CAKKSDINNIGWHGLFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcacctttggtaattatgccatgcactgggtccggcaagctccagggaGggggcctggagtgggtctcaggtattagttggaacagtggtagcatagactatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcgaaaaaatcggatataaataacattggctggcacggcctatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18054 JY8QFUQ01AC3PJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-59*08 F 993 96.26 206/214 nt 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CAREDGSGRRHFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagtagttactactggagctggatccggcagcCccccaggaaagggactggagtggattgggtatatcttttacactgggaccaccaactacaacccctccctcaagagtcgagtcaccatgtcaatagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtctattactgtgcgagagaggacgggtccggcagacgtcactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18055 JY8QFUQ01AF9LD productive (see comment) Homsap IGHV3-7*01 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaAagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18056 JY8QFUQ01C0IWS unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.37.11] CAREKGSGPPTGMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagcccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctgggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc 18057 JY8QFUQ01DGFIA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18058 JY8QFUQ01BIZKT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18059 JY8QFUQ01CY0IP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcacctacagcagcGtatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18060 JY8QFUQ01CI7HZ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAGHLLGDPFDYW in-frame - ggttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18061 JY8QFUQ01CTMBK No results 18062 JY8QFUQ01AZPY0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18063 JY8QFUQ01DMSZS unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFDY## out-of-frame + tctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggcccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcacctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18064 JY8QFUQ01B5GC9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 495 69.59 151/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] VHT#AFW out-of-frame + Low V-REGION identity (69,59% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgaggacaactttggtgaacacgccatgggatggatccgccagtctccgggggggattcttcagtgggtcgctgcgatcagtggtgacggactgacggcgtttcacgcagacttcgtggagggtcgattcagcatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctattttgtgcacacactgccttctggggccggggatcccgggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18065 JY8QFUQ01CT4VQ No results 18066 JY8QFUQ01DNI3E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame - ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18067 JY8QFUQ01A18TB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 978 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 X 8.8.X [2.17.38.11] CARGLAVFLE#FDYW out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtagttatagcatgnactgggtccgccaggctccagggaagggactggagtgggtctcctCccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgttcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18068 JY8QFUQ01B6TBA No results 18069 JY8QFUQ01DGWLB No results 18070 JY8QFUQ01CAI91 productive (see comment) Homsap IGHV3-9*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaattttagcaattatgccatgaactgggtccgccaggctccagggaagggcctggagtAgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18071 JY8QFUQ01CEBK2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18072 JY8QFUQ01DGYOH No results 18073 JY8QFUQ01CPJ2X productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18074 JY8QFUQ01CCKOI productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaGgaatttattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18075 JY8QFUQ01CQZEF productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18076 JY8QFUQ01DCDNV productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 18077 JY8QFUQ01C2EGT unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt 95.35 205/215 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDNYGDYW# out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 90 to 91 in the user submitted sequence), (cause frameshift); ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 18078 JY8QFUQ01ARZ7N No results 18079 JY8QFUQ01BLVG5 unproductive Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARQRGGGDRSG#FENW out-of-frame + in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatTttttgtgcgagacaaagaggcggcggcgaccgcagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcaccctctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18080 JY8QFUQ01AHHL6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ccctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18081 JY8QFUQ01BZ3MR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 688 80.09 173/216 nt 79.63 172/216 nt 7 8 X 7.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggtttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18082 JY8QFUQ01AN30B No results 18083 JY8QFUQ01AQ4B3 unproductive Homsap IGHV3-33*05 F (see comment) 729 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.16.38.11] CVKGRGYNDYGLDY## out-of-frame - Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) gcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccagcaagggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactgggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18084 JY8QFUQ01ANPIM No results 18085 JY8QFUQ01AU2DJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKSIIIRGLI#YNFDYW out-of-frame + ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaagcattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18086 JY8QFUQ01AFPBP unproductive (see comment) Homsap IGHV3-74*03 F 869 88.99 194/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLGGQKGH## out-of-frame + stop codons cctcaggattcaccttcaggagttactggatgcactgggtccgccaagctccagggaaggggccgatgtgagtcgcacgtcttaatgaagatggcagctacacaacttacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacaagctctatttgcaaatgagcagtctgagagttgaggacacggctgtctattactgtgtaagcgatttgggtggtcagaaaggtcactggggccagggagcccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttccccgctgagcctcgacagcaccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18087 JY8QFUQ01CMNOI productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18088 JY8QFUQ01CBP29 productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18089 JY8QFUQ01DDFKI No results 18090 JY8QFUQ01BUUXL productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 407 79.39 104/131 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Low V-REGION identity (79,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18091 JY8QFUQ01CPY4L No results 18092 JY8QFUQ01AKIZN productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'TG' (2 nucleotides at position 37 to 38 in the user submitted sequence), (cause frameshift); tttccggtagttccatcagtagcagtgattactactTGggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattacagggggacgcagtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgaggtctgtgaccgccgcagacacggctatgtattactgtgcgagacatcggtcttttggagtgataattgtgaattactttgagacctggggacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18093 JY8QFUQ01APXOI No results 18094 JY8QFUQ01BBX78 productive (see comment) Homsap IGHV3-30*04 F, or Homsap IGHV3-30*07 F or Homsap IGHV3-30*15 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*06 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cttctggattcacctctggtgattatgctatgagctggctccgccaggctccagggaaggGggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18095 JY8QFUQ01C411I productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - aggcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18096 JY8QFUQ01B68DP productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-8*02 F 3 8 7 14 8.7.14 [1.17.38.11] CARGRCGLVGCWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtggttactactggagctggatccgccagtccccagggaaggggctggagtggatcggggaaatcaatcataatggatccaccagctacaacccgtccctcaagggtcgagtcaccatatcagtagacacgtccaagaaccagttctccctaaagctgagttctgtgaccgtcgcggacacggctgaatatttctgtgcgagaggtcgctgcgggcttgtggggtgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18097 JY8QFUQ01BGRWQ unproductive Homsap IGHV3-30*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F (see comment) 78 62.5 30/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [2.17.38.11] CSNGYGDFPRRW# out-of-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgttcgaatggttacggtgacttcccgcgtaggtgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18098 JY8QFUQ01A0ZW5 productive Homsap IGHV4-61*02 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame + tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccggggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18099 JY8QFUQ01CAQER unproductive Homsap IGHV3-7*01 F 1058 98.62 215/218 nt 97.71 213/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CARSLVGADVFDY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagctattggatgagctgggtccgccaggctccaggGgaaggggctggagtGgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgactcaccatctccagagacaatgccaagaagtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggtcgttagtgggagctgacgtatttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 18100 JY8QFUQ01B1X6H productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 795 85.51 183/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [0.17.38.11] CVRVRDYEIGGDFW in-frame + tggaggcgccttcagcacctttcatatcacctgggtgcgacaggcccctggacaagggcttgtctggctggggaatatcattcctatttttggaacagtcgactacgcacgggggttccagggcagagtcacgattaccgcggacgaatccaccaacacagcctacatggagttgagcagcctgacatctgaggactcagccgtctatttctgcgtgagagttcgtgactatgaaattggtggtgacttctggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaac 18101 JY8QFUQ01CU723 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F (see comment) 266 67.72 86/127 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found Low V-REGION identity (67,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18102 JY8QFUQ01BPS3D productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18103 JY8QFUQ01CQG5W No results 18104 JY8QFUQ01CPM0Z unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons tctgattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18105 JY8QFUQ01C3ODE No results 18106 JY8QFUQ01B40ET unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame - stop codons in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggagggggActggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18107 JY8QFUQ01AIEID productive (see comment) Homsap IGHV4-39*07 F 874 89.04 195/219 nt 88.58 194/219 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 10 6 10 10.6.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagcccccagggaaggggctggagtggattggacaaatccatcatgtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttct 18108 JY8QFUQ01B1E0Q unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 723 80.72 180/223 nt Homsap IGHJ3*01 F (see comment) 133 74.0 37/50 nt Homsap IGHD3-9*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDSPTGYYAF##VW out-of-frame + Low V-REGION identity (80,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgcatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18109 JY8QFUQ01AI3J7 unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgagGgacacGggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18110 JY8QFUQ01BXZ1R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 18111 JY8QFUQ01CKQGV productive Homsap IGHV1-8*01 F 963 96.15 200/208 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-15*01 F 2 6 8 21 6.8.21 [X.17.38.11] CARRVGRWLRGDPRRLYYGMDVW in-frame - caccttcagcagtgatgatatcaactgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagtggaaacacaggctatgcacagaagttccagggcagagtcagcatgaccaggaacacctccataagcacagcctacatggacctgagcaacctgagatctgaggacacggccatatattactgtgcgagaagagttggaaggtggcttcggggagacccgcgacggctctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18112 JY8QFUQ01A4YPX unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDNYGDYW# out-of-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18113 JY8QFUQ01BERAB unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18114 JY8QFUQ01CQSW9 productive Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18115 JY8QFUQ01DLDNS productive Homsap IGHV4-4*07 F 840 87.91 189/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.38.11] CARDSGDFDYW in-frame - tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggaccccccactacaacccttccctnaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccatttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18116 JY8QFUQ01BTOS2 productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 908 91.63 197/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 7 10 8.7.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcaGgtaacaactacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatcccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 18117 JY8QFUQ01BE0SM unknown (see comment) Homsap IGHV3-19*01 P, or Homsap IGHV3-48*01 F 129 51.79 101/195 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18118 JY8QFUQ01DQLNG unproductive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARWRGQQSE*Y# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaatgatactgggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18119 JY8QFUQ01BL7KX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 778 84.72 183/216 nt 83.8 181/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.16.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaagggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtTttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18120 JY8QFUQ01CULLC productive Homsap IGHV3-7*01 F 919 91.32 200/219 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [2.17.38.11] CSRLLEEW in-frame - cctctggttttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18121 JY8QFUQ01BTHCZ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1019 95.93 212/221 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [1.17.38.11] CAWGGSG*#YFDYW out-of-frame + stop codons tctctggtggctccatcagcagtactagttactactggggctggatccgccagcccccagggaaggggctggagtggattggtaacattcattctagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcatggggtggttcgggttgaactactttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18122 JY8QFUQ01BCXG9 No results 18123 JY8QFUQ01AYT0Y unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 18124 JY8QFUQ01CNLFV No results 18125 JY8QFUQ01AF7AJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18126 JY8QFUQ01B1UP0 productive (see comment) Homsap IGHV4-4*07 F (see comment) 746 83.26 179/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARERSISIGGAREFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 37 of V-REGION: 'ATA' (3 nucleotides at position 29 to 31 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); tcactggtggccccatgggcagtagtttATActtctggaattgggtccgacaGgcccgccgggaagagactggagtggatcggAcgtggtttatgatgatgggagtacccgctacaatccctccctcaggggtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaggttgagttttgtgaccgccgcagacacggcccgttattactgtgcgagagaacggagtatttcgattggcggagcgagagaatttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18127 JY8QFUQ01CVHKX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVSDLAGQKGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'TG' (2 nucleotides at position 50 to 51 in the user submitted sequence), (cause frameshift); aggattcaccttcagtaggtactggatgcactgggtccgccaagttccaTGggaaggggaccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 18128 JY8QFUQ01CEYYX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtacatactggatgcactgggtccgCccaagctccagggaaggGggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18129 JY8QFUQ01BYBVC unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt 99.53 214/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18130 JY8QFUQ01BV99D productive (see comment) Homsap IGHV3-64*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaTttttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18131 JY8QFUQ01AFHQC productive (see comment) Homsap IGHV4-34*03 F 885 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 7 16 8.7.16 [1.16.38.11] CVRNYMILVVISIGSTPG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tgtctggtgggtccttcagtggttactactggagttggatccgccagccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattatatgattttagtggttatttcaattggttcgactcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18132 JY8QFUQ01C6GTE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 765 83.87 182/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18133 JY8QFUQ01DK33J unknown (see comment) Homsap IGHV4-39*02 F 946 92.69 203/219 nt 91.32 200/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.16.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 2 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagtccccagggaaGggggctggagtgattggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactgggggccgggggaacccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18134 JY8QFUQ01ASFLD unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*01 F (see comment) 99 61.9 39/63 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDRELHYQHLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaAatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctgggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18135 JY8QFUQ01AVDHQ productive Homsap IGHV3-9*01 F 945 93.09 202/217 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD4-17*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARLPGDYGSRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaactttgataaatatgacatgcactgggtccgacaagctccagggaagggcctggagtgggtctcaggtattaagtggaatggcggtcgcgtcggctatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagacctgaggacacggccttctattactgtgcaagactccccggtgactacgggtctcgttggggccagggaaccctcatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18136 JY8QFUQ01BSRSP productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + ctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtcaccgtctcctaccatccccgaccagccccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18137 JY8QFUQ01CA3DQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaagccctggctnaccgtctcctcagcatcccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 18138 JY8QFUQ01CERC2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.37.11] CARSSDYLWGSYRYPYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 150 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagttacttctggagttggatccggcagcccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgactagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18139 JY8QFUQ01CBF2O unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 18140 JY8QFUQ01BUAS2 productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18141 JY8QFUQ01AKD9K productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagnacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 18142 JY8QFUQ01A3P8I productive Homsap IGHV3-30*19 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWGTIESYFDYW in-frame + cgtctggattcaccttcagaacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatcatatgatggaagtaatatatactactcagactccgtgaagggccgattcaccatctccagagacaattccaaggacacgctgtatctgcaaatgaacagcctgagagctgaggacgcggctgtatattactgtgcgagaaatgagctgccttggggtacgatagagtcctactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18143 JY8QFUQ01AP263 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18144 JY8QFUQ01DJGLE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18145 JY8QFUQ01A2XEM productive (see comment) Homsap IGHV4-61*02 F 887 89.5 196/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.37.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 72 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 81 of V-REGION: 1 nucleotides (from position 151 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtactggttattactactggGagctggatccggcagtccnccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagaacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18146 JY8QFUQ01DKDCG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18147 JY8QFUQ01BRZ0F No results 18148 JY8QFUQ01CFTFO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGVGAYYIYYFDLW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 18149 JY8QFUQ01ALJS1 productive Homsap IGHV3-21*04 F, or Homsap IGHV3-23*01 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18150 JY8QFUQ01C7FFT No results 18151 JY8QFUQ01CTX39 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtCagtgactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18152 JY8QFUQ01CADD3 No results 18153 JY8QFUQ01CEYH3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 592 91.49 129/141 nt 90.78 128/141 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 3 8 X 13 8.X.13 [1.2.35.11] CARGRYGDQVTWDYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 41 of V-REGION: 76 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctataccttgagttggatgcagtgaagggccgattcaccatttccagagacaacgccaagaactccctctctctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagaggtcgctacggtgaccaagtaacctgggactactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18154 JY8QFUQ01BW65G No results 18155 JY8QFUQ01CRQ67 No results 18156 JY8QFUQ01CCN00 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 13 8.8.13 [2.17.38.11] CARGGGGKSIPLDNW in-frame - gcgtctggcttcacgttcagtagttatggcatgcaatgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaatattatgcagactccgtgaagggccgattcgacatctccagagacaattccaagaacacactatatctgcaaatgaacaacctgagagccgaggacacggctatgtaccattgtgcgagaggcggcggtggtaagtccattccacttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18157 JY8QFUQ01BP9B9 No results 18158 JY8QFUQ01DEBXU productive Homsap IGHV3-11*04 F, or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F 977 92.51 210/227 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [4.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggctgacggtgtcgtggaactc 18159 JY8QFUQ01BM1BK No results 18160 JY8QFUQ01AWCIW unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 640 85.55 148/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgc 18161 JY8QFUQ01AECK2 No results 18162 JY8QFUQ01CHTU1 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 933 93.84 198/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 3 8 7 X 8.7.X [0.17.38.11] CARGDGLR#DYW out-of-frame + tggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacgggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18163 JY8QFUQ01AIYO5 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccancccctcaaggtttcccgctgagcctctgccagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18164 JY8QFUQ01DREX7 No results 18165 JY8QFUQ01CN0EQ No results 18166 JY8QFUQ01BPWU6 productive (see comment) Homsap IGHV4-39*02 F 915 90.91 200/220 nt 89.55 197/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 9 7 14 9.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) tctctggtgGgctccgtcagtaggagtccctatactggggctGggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18167 JY8QFUQ01CZEZJ productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 820 86.3 189/219 nt 85.84 188/219 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CVRDLNWSFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatGacaaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18168 JY8QFUQ01CGQAI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame - ctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18169 JY8QFUQ01C4JSD productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 18170 JY8QFUQ01CL36G productive (see comment) Homsap IGHV3-48*01 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDGGLYGTLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); acctctggattGcacctttagtaaccatTgggatgaactgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaaagactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagacgggggactctacggtactcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18171 JY8QFUQ01BS7GX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CTKVASQVIMATTYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); agcctctgaattcacttttagtacctatgtcataagttgggtccgccaggtcccagggaAaggggctggagtgggtctcaagtattgttgatggtggtgatatcacacactacgcagactccgtgaagggccggttcaccatctccagagacgaatccaagaacactgtctatctgcaaatgaacagcctgagagccgaggacacggccgtgtactactgtacgaaggtggcgagtcaagtgatcatggctacaacctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18172 JY8QFUQ01AE11Y No results 18173 JY8QFUQ01B6450 productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactcttcccccgaaccgggtgacggtgtcgtggaacctcagg 18174 JY8QFUQ01CAT3O unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD1-1*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGSSKAYNWFD#PG out-of-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc 18175 JY8QFUQ01CH4GT productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1055 100.0 212/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [0.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18176 JY8QFUQ01BMV5F unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDASRYYYNSYCDN## out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccGaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctattcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18177 JY8QFUQ01B6DQJ productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18178 JY8QFUQ01DR7OC unproductive Homsap IGHV3-48*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRGYSNGLRYYAMDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'T' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cctctggattcggcttcagtgactatggcatgaactgggtccgacaggctccagggaagggtctggagtgggttgcctatcttagtagtagtagttTttatcatatattatggagactctgtgaagggccgattcaccatctccagggacaatgccaacaactcactgtatctacaaatggacagcctgagagacggcgacacggctgtttattactgtgcgagagatcgtggatacagcaatggacttcgctactatgccatggacgtctggggcccaagggacaacggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18179 JY8QFUQ01DJKRD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcacctttggttattatggcatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18180 JY8QFUQ01CFTZX productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18181 JY8QFUQ01CW6SR productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18182 JY8QFUQ01A4RGQ productive Homsap IGHV3-72*01 F 966 92.83 207/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD7-27*01 F 1 8 10 10 8.10.10 [1.17.38.11] CVRDPFSSRGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18183 JY8QFUQ01CMRMI productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGGEDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggGggctggagtgggtctcacgtattaatgaagatgggaggactacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacaccaagaacacactgtatctgcagatggacagtctgagagccgaggacacggctgtgtattactgttcaaaagacacctttgggggagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacggggtcgtcgcatgcctggtccagggcttcttccccca 18184 JY8QFUQ01AI52U productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtttcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18185 JY8QFUQ01CRA60 productive (see comment) Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARSGSGSHLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); gtctctggattcacctTttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18186 JY8QFUQ01BWE6J productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18187 JY8QFUQ01CECS2 No results 18188 JY8QFUQ01DJ7Q8 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18189 JY8QFUQ01A202Z No results 18190 JY8QFUQ01C0FW1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1053 98.62 214/217 nt 97.7 212/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'TC' (2 nucleotides at position 10 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); ctctggattTCaccgtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18191 JY8QFUQ01A4A0G No results 18192 JY8QFUQ01B8CJH No results 18193 JY8QFUQ01A3W9F productive Homsap IGHV4-4*07 F 877 89.81 194/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [2.17.38.11] CARFSSYGDTFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctctgatgggtccatcggaagttactactggacttggatccggcagcccgccgggaaggcaatggagtggatcgggcgtgtctttagaactgggaacacgaattacaacccctccctcaagagtcgggtcaccatgtcagttgacacgtccaagaatcaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgttttactgtgcgagattctcgtcctacggtgacacctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 18194 JY8QFUQ01BUNR5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD2-8*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKGASTAVMVSGTDCYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattccccttcagcacctatcccatgagctgggtccgccaggctccagggaggggactggagtgggtcgcaactataagtggtggaggttatagtatatatgacgcagactccgtgaagggcaggttcaccatctccagagacaactccaagaccaccttgtttctggaaatgaaaagtctgagagtcgatgatacggccgtctattactgtgcgaaaggggcctcgactgcagtaatggtgtctggaacagattgttacggtttggacgtctggggccacgggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18195 JY8QFUQ01BUB3X productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + tctctagattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcc 18196 JY8QFUQ01BCH3I No results 18197 JY8QFUQ01CCC1O productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 172 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGXYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcgggganttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18198 JY8QFUQ01CNJM1 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 920 90.95 201/221 nt Homsap IGHJ6*02 F (see comment) 89 59.68 37/62 nt 10 7 18 10.7.18 [1.17.38.11] IVRRGKWGDKPPFYYGMDVW (see Functionality comment) in-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctgattgattgtncgacgagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaaggaccacggtcaccgtntcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18199 JY8QFUQ01DBEYG unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*03 F 728 87.7 164/187 nt 8 8 X 8.8.X [1.17.28.X] null + No rearrangement found ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctg 18200 JY8QFUQ01CU30A unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 18201 JY8QFUQ01CBMWP No results 18202 JY8QFUQ01BYAI8 productive (see comment) Homsap IGHV3-9*02 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [2.17.38.11] CGKDMRPGGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); gcctccggattcacctctgGaaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18203 JY8QFUQ01DGNP4 productive (see comment) Homsap IGHV3-49*04 F 970 93.24 207/222 nt 92.34 205/222 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [2.16.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) ggctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccaggaagggctggagtggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18204 JY8QFUQ01BWU5P productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt 84.62 187/221 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-16*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARTYTYRNAFDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'CAGT' (4 nucleotides at position 29 to 32 in the user submitted sequence), (cause frameshift); tctttggtgactctctgagtaccagtagCAGTtttctactggggctgggtccgccaggccccagggaagggactggagtgggttgggactgtttattatagtgggagcgcccactacaatccgtccctcaagagtcgagtcgccatatccgtggacacggcccaaaaccaggtctccctgactttgaactctgtgaccgccgcagacgccgctgtctatttctgtgcgagaacttatacttatagaaatgcttttgacgtctggggccaggggacattggtcgctgtgtcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18205 JY8QFUQ01CANLM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 998 96.28 207/215 nt 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18206 JY8QFUQ01CDZ5R productive (see comment) Homsap IGHV3-30*01 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*01 F 97 66.0 33/50 nt Homsap IGHD2-2*02 F 2 8 7 11 8.7.11 [1.17.38.11] CACGHMRDGYDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggcccaagggacaaaggtcaccgctcttcatcatgcccgatcccgacccaaggtccagttcctgccgtctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18207 JY8QFUQ01DBU74 unproductive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKGRGYNDYGLDY## out-of-frame - Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactgggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18208 JY8QFUQ01B728J productive (see comment) Homsap IGHV3-7*01 F 904 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctggattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 18209 JY8QFUQ01A901C productive Homsap IGHV3-11*01 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CVREVTGVWDWFDPW in-frame - cctctggattcaccttcaaagactactatatgacctggatccgccaagttccagggaaggggctggagcggatctcatatatcagtggcagtggtggcaccatttactacgcagactctgtgaagggccggttcgccatctccagggacaacgccaagaacttactatacttacagatgaacagcctgagagtcgaggacacggccatatatcactgtgtgcgagaagtgactggagtctgggactggtttgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18210 JY8QFUQ01CJ3NN productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*02 F 1 8 8 10 8.8.10 [1.17.38.11] CAREFWWRLDFW in-frame - cctctggattcacctttagtggccattatatgacctgggtccgtcaggctccagggaaggggctggagtgcgtggccaagataaagccagatggaagtgaggaattctatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctgcaattgaacaccctgagagtcgaggacacggctatttatcactgtgcgagagagttctggtggcggcttgacttctggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggaggcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18211 JY8QFUQ01DLIX0 No results 18212 JY8QFUQ01CWPJP productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt 87.33 193/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'G' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaAaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagGttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18213 JY8QFUQ01CG6XI productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame + cctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggcttcttccccca 18214 JY8QFUQ01AF1EK unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18215 JY8QFUQ01A5V24 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaccc 18216 JY8QFUQ01B5L4G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18217 JY8QFUQ01B09U4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame - cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18218 JY8QFUQ01AFUZV productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18219 JY8QFUQ01CHKE9 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18220 JY8QFUQ01BNAXM productive (see comment) Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagtaattactGggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 18221 JY8QFUQ01CLRF1 No results 18222 JY8QFUQ01CO5ED productive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 761 83.49 182/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARDPGFSAFDYW in-frame - Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaacttcagagattattggatgagctgggtccgccagactccggggaaggggctggagttcgtggccaacataaataaagatggaagtgtgaggaactatgtcgactctataaaggggcgatccagcatttccagagacaacgcccagaatttaatgtttctgcagatgaacggcctgagggccggcgacacggcaatatattactgtgcgagagaccccggcttttccgcttttgactactggggccagggaatcctggtcaccgtctccccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18223 JY8QFUQ01AVOIO productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 805 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 8 9 7.8.9 [2.16.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) acgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaagggctgacttgggtctcacgnattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18224 JY8QFUQ01ABGCX productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) cttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18225 JY8QFUQ01AI46E productive (see comment) Homsap IGHV3-30*07 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [2.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18226 JY8QFUQ01BSQQU No results 18227 JY8QFUQ01AH4LA productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - tctggagttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18228 JY8QFUQ01BNDD3 productive Homsap IGHV3-7*03 F 846 88.02 191/217 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccccaaggcttcttccccc 18229 JY8QFUQ01CV6WG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame - ctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18230 JY8QFUQ01BY9OT unproductive Homsap IGHV3-7*01 F 928 91.78 201/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CAISSGFTRR#YW out-of-frame - ggctctggagttcagcttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18231 JY8QFUQ01CIXN5 productive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDELPWDTIEYYFDYW in-frame + ctctggattcaccttcaatacctattctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18232 JY8QFUQ01AW4QC unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 783 92.78 167/180 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattga 18233 JY8QFUQ01DDZ72 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18234 JY8QFUQ01CPT27 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18235 JY8QFUQ01CBRTT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18236 JY8QFUQ01CGHQC productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18237 JY8QFUQ01CM97Q No results 18238 JY8QFUQ01C0EZ2 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcgtgcttctacccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18239 JY8QFUQ01BD9E4 No results 18240 JY8QFUQ01B9NGM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 984 93.72 209/223 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame - ctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18241 JY8QFUQ01DIDUE productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18242 JY8QFUQ01BLFUH productive Homsap IGHV4-39*02 F 834 86.82 191/220 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18243 JY8QFUQ01AQN4P productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame - ttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18244 JY8QFUQ01AXASL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 907 92.02 196/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 7 12 8.7.12 [0.17.38.11] CARDTGQWKDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) tggattcagcttcagtacctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18245 JY8QFUQ01DFEC5 unproductive (see comment) Homsap IGHV3-30*01 F 846 88.02 191/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CVGGQ*PAPGG#FNYW out-of-frame - stop codons in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); ctctggattcaacttcaatggctttaatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagAttttgtcatatgatggaaAataataagttctacgcagactccgtgagtggccgattcaccatctccacagacagttccaagaggacattgtttctgcaaatgaacaacctgacaactgaagacacgGgctctttattactgtgtggggggacagtagccggccccggggggccttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18246 JY8QFUQ01CCQ82 productive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18247 JY8QFUQ01BBXFA No results 18248 JY8QFUQ01C39NJ No results 18249 JY8QFUQ01AIHLU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 86.18 187/217 nt 85.25 185/217 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctgggattcaGcgttaagttcttatggcatgaactGgggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18250 JY8QFUQ01CA4R1 productive (see comment) Homsap IGHV3-7*01 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggatttacttttacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaaaCgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18251 JY8QFUQ01APB0H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18252 JY8QFUQ01BTVIS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 563 72.94 159/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (72,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctagattcatctttagtagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactatcagtggtagtggtgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18253 JY8QFUQ01AFI4A No results 18254 JY8QFUQ01AZXKI unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18255 JY8QFUQ01CU8RS productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18256 JY8QFUQ01BVVHP productive (see comment) Homsap IGHV3-7*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagcagacattggatgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacatGaaaacaagatggaagtcagagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgaggggtagagatggtgttaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18257 JY8QFUQ01BCL4K productive Homsap IGHV3-48*04 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CAKKSDINNIGWHGLFDYW in-frame - gcctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttgtattactgtgcgaaaaaatcggatataaataacattggctggcacggcctatttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18258 JY8QFUQ01BEUMV No results 18259 JY8QFUQ01A3QNJ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [2.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gtctctggggactccattagtggttactattggacgtggatccggcagAgccccagggaagggactggagtggattggaaatgtccattacacCtgggagtaCccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18260 JY8QFUQ01ACFX8 productive Homsap IGHV3-30*10 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-9*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARDRDFDFPAYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacttcagtaactatgctgtgcactgggtccgccgggctccaggcaaggggctagagtggatgggagttatatcatttgatggagataataaatactacacagactccgtgaagggccgattcaccatgtctagagacaattccaagaacacactatatctccaaatgaacagcctgtcagctgaggacacggctgtctattactgtgcgagagatcgagatttcgactttcctgcttacggtttggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 18261 JY8QFUQ01CN8I9 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggGggagggactggtgtgggtctcacGggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18262 JY8QFUQ01BK3V9 No results 18263 JY8QFUQ01A9DN8 No results 18264 JY8QFUQ01AC792 productive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18265 JY8QFUQ01DHE9K productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccGtttagtagtcatgtcatgagctgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18266 JY8QFUQ01A840J productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-1*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccCccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgattaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgctgcctggtcagggcttcttccc 18267 JY8QFUQ01BR8K6 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18268 JY8QFUQ01CTSDS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame + cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18269 JY8QFUQ01AH8S9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.11 182/219 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tgtctgggattcacatttagaagctattccatgaattgggtccGgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18270 JY8QFUQ01CF84W unknown (see comment) Homsap IGHV3-16*01 ORF 94 53.45 62/116 nt 8 X X 8.X.X [25.5.X.X] null - No rearrangement found ctctggattcacctttagtagttctgccatgaactggaggagtctgggggaggcttggttcagccgggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18271 JY8QFUQ01B1X2K unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFEPYDY## out-of-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaacccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 18272 JY8QFUQ01B6PJB No results 18273 JY8QFUQ01A953W unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-8*01 F 3 8 8 21 8.8.21 [1.17.38.11] CANACPPV*LGNVFLLLRYGTSG in-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctggattcaTcgttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctgcccccccgtataactgggaaacgtatttctactactacggtatgggacgtctgggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18274 JY8QFUQ01ADV0A productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARHGSGWLQELDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcatcagagacagtgcctactGggggctggatccgccagcccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18275 JY8QFUQ01A5AIL unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 853 89.2 190/213 nt 88.26 188/213 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.16.38.11] CGRGDGG#DLW out-of-frame - stop codons in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctctggattcacggttgaggattatggcgtgagctgggtcgccaagttccagggaaggggctggagtgggtctctggtcttaatttgaatggtgccacaggttatgcaaagtccgtgacgggccggtttaccatctccagagacaacgccaagaactccctgtatttggaaatggatagtctgagagtcgaagacacggccttctattattgtgggagaggggacggggggtgacctctggggccggggaatcctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18276 JY8QFUQ01AVVFN No results 18277 JY8QFUQ01DQOUI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18278 JY8QFUQ01B0U8B productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 18279 JY8QFUQ01CGQJT unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 118 58.7 54/92 nt 56.52 52/92 nt 8 X X 8.X.X [21.1.X.X] null - No rearrangement found in FR1-IMGT, from codon 14 of V-REGION: 2 nucleotides (from position 101 in the user submitted sequence), (cause frameshift)in FR1-IMGT, from codon 20 of V-REGION: 10 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) ggggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttggggctggtcggggatgctgggggctggcggatgcagttccaggagtaaccactgaaggacccaccacaga 18280 JY8QFUQ01B9YY8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18281 JY8QFUQ01CRU68 No results 18282 JY8QFUQ01AND2L productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 929 91.4 202/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame - tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18283 JY8QFUQ01A9PZ9 unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18284 JY8QFUQ01CNHSH productive Homsap IGHV3-72*01 F 962 92.41 207/224 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.17.38.11] CARLHYSGGWYGLDVW in-frame + cctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtgggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagatgactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18285 JY8QFUQ01DRLB3 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18286 JY8QFUQ01CMIFO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18287 JY8QFUQ01ASQRV No results 18288 JY8QFUQ01CTDQI unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 679 94.08 143/152 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaac 18289 JY8QFUQ01A8464 productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccagccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18290 JY8QFUQ01ARQT4 productive Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18291 JY8QFUQ01CD4E0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 8 18 8.8.18 [1.17.38.11] CARESGDYDGKYSKSYLDYW in-frame - cctctgggttcagcttcgattcctataccctgaactgggtccgccagactccagggaaggggctggagtgggtctcatccatcagcagaagtagtagttatgtatactacacagactcggtgaagggccgcttcaccatctccagagacaacgccaggaactccctgtctctgcagatgaacagcctgagagccgaggacacggctgtttattactgtgcgagagaatcgggtgactacgatggtaaatatagcaagtcatatcttgactattggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctagtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18292 JY8QFUQ01CMEU9 unproductive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [1.17.38.11] CTREGGRGSSSEDY#LDYW out-of-frame + ctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaggaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtacgcgagagggggggcggggcagttcgtcggaagactactttggactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18293 JY8QFUQ01CCTBO productive Homsap IGHV1-18*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARSHGEQQLDEFDFW in-frame + Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tggttacatctttaccagctatggtatcagctgggtgcgacaggcccctggacaaggacctgagtggatgggatggatcagctcttacaatgggaacgcaaactttgcacagaagttccacggcagagtcgccatgaccacagacacatcctcgagcacagcctacttggaactgaggagcctgagatctgacgacacggccatgtattactgtgcgagatctcacggggaacagcagctggacgaatttgacttctggggccaggggaccgtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18294 JY8QFUQ01AVTU7 productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F (see comment) 706 81.02 175/216 nt 79.63 172/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.16.38.11] CARLKGLTHHDFYFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 66 of V-REGION: 'TACT' (4 nucleotides at position 105 to 108 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaagggccggagtgggtggccaacatatccccagacggaaagtacgaaaaTACTttttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18295 JY8QFUQ01AUH7W No results 18296 JY8QFUQ01DRN8J productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 848 87.33 193/221 nt 86.88 192/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CAKYSGGWTSIFDGW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'AT' (2 nucleotides at position 16 to 17 in the user submitted sequence), (cause frameshift); cagcctctggattaaATtttttcccagtatggccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactgttagtggtgatgctggtgacatatactacgcagactccgtgaggggccggttcaccatctcgagagacaattccaagaacacggtcattctgcagatgaacagcctgagagtcgaggatacggccatatatttctgtgcaaaatatagcggtggctggacatcgatttttgacggctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18297 JY8QFUQ01C8G26 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 807 85.45 188/220 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + ctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 18298 JY8QFUQ01BB8B1 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 899 91.16 196/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01BB8B1 ; 7 AA in Homsap_IGHV3-53*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcaccgtcaatagaaactacatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18299 JY8QFUQ01BMPPM productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 18300 JY8QFUQ01CGV8T productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 783 83.19 188/226 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [2.17.38.11] CSTGGPNGYHSTYPW in-frame - Low V-REGION identity (83,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) agcctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18301 JY8QFUQ01C0KMS unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 18302 JY8QFUQ01A5AW4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18303 JY8QFUQ01DECQU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 878 89.45 195/218 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD6-25*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGRGQQREDAFDIW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcatcttcagtagttatagtttgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatatgagtagttcttacatctattatggagactcagtgaggggccgatttaccatctccagagacaacgccgagagctcactgtatctgcagatgagcagcctgagagccgaggacacggctttatattattgtgtgagaggcgggagggggcagcagcgagaagatgcttttgacatttggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 18304 JY8QFUQ01BMLP2 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARAKRFGAPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagcaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18305 JY8QFUQ01AGKQJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18306 JY8QFUQ01A7D7G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 18307 JY8QFUQ01CN6AC productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 866 90.09 191/212 nt 89.15 189/212 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.16.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaagggctggagtgggtctcagTttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18308 JY8QFUQ01A5XDS productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18309 JY8QFUQ01CR20N No results 18310 JY8QFUQ01C4YE8 productive (see comment) Homsap IGHV3-9*02 F (see comment) 729 82.03 178/217 nt 80.65 175/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 8 8 19 8.8.19 [1.17.38.11] CVKDKDKVGGHTGHYPTFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'A' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 99 of V-REGION: 'G' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); ctctggattcaaccccgaaaactttgccatgcactgggtccgacaagttccagggaagggAcctgaagtgggtctcaggtataaattggaatggacgaaaaacaggatatgcggagtctgtgaggggccggttcaccatctccagagacaatgacaagaacgtcctttctttgcaaatgaccAattttggggactgaggacacGggccttctatttttgtgtgaaagataaggacaaagtggggggccacactggccattatcccacgtttgacttctggggccagggagccctggttaccgtcgcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18311 JY8QFUQ01ACVZ2 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 94 52.24 70/134 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18312 JY8QFUQ01B93WH productive (see comment) Homsap IGHV4-61*02 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.37.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggGggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18313 JY8QFUQ01AV2V7 productive Homsap IGHV3-72*01 F 930 91.03 203/223 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-3*01 F 2 8 10 14 8.10.14 [1.17.38.11] CLRGFSSHYRGGMDVW in-frame - ctctggactcacgttcagtgaccactacatggactgggtccgccagactccagggaggggactggagtgggttggccgtattagagacaaagctcgcaggtacaccacagaatacgccgcgtctgtgaaaggcagattcaccattttaggagatgatttaaagaattcactgtatctacaaatgaacaacctgagaaccgacgactcggccgtgtattactgtctcagaggattttcgagccattatcggggcggtatggacgtctggggccaagggaccacggtcaccgtgtccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18314 JY8QFUQ01B0Z32 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASDLGGQKSYW in-frame + ctcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18315 JY8QFUQ01CJVW9 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccaCgttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18316 JY8QFUQ01AQQDB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); aggctctgacttGcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18317 JY8QFUQ01BCZ6T productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + cctctgggttcaccgtcagtagcaagttcatgagctgggtccgccagggtccagggaaggggctggagtgggtctcagttacttatcctgatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18318 JY8QFUQ01CI4FK unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggattcaccttcatcagttatggcatgagttgggtccgccagtTttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtatattactgtgcgagagggtacagtcaaaaatggggtttttcgaccactggggccaggggtaatcctggtcaccgtttccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccga 18319 JY8QFUQ01BNSUQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18320 JY8QFUQ01AW4RF productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18321 JY8QFUQ01CHX7Q productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 957 92.38 206/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + ctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18322 JY8QFUQ01C37YG productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18323 JY8QFUQ01C1L9B productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - ctctagggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18324 JY8QFUQ01BAA2B productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 199 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + ctctggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcaggganccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18325 JY8QFUQ01B1FGN unproductive Homsap IGHV3-13*01 F 961 94.84 202/213 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD1-1*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGSSKAYNWFD#PW out-of-frame - tctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18326 JY8QFUQ01CERMV unproductive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame + in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); cctctggattcaggtttagcatctattggatgagctgggtccCgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccaggggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttcccccag 18327 JY8QFUQ01AQALS productive Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame - Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18328 JY8QFUQ01BSME5 productive (see comment) Homsap IGHV4-4*07 F 872 89.77 193/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARFSSYGDTFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); tctctgatgggtccatcggaagttactactggacttggatccggcagcccgccgggaaggcaatggagtCggatcgggcgtgtctttagaactCgggaacacgaattacaacccctccctcaagagtcgggtcaccatgtcagttgacacgtccaagaatcaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgAttttactgtgcgagattctcgtcctacggtgacacctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18329 JY8QFUQ01BRRDS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARGDSADAYNYYRYW in-frame + ctctggattcaccttcactagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatagtgatggaagtagtacaacctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtctctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaggggatagtgcagatgcctacaattactaccgctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18330 JY8QFUQ01DCYKK unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18331 JY8QFUQ01CMWEB No results 18332 JY8QFUQ01CLVE2 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18333 JY8QFUQ01B7ESX No results 18334 JY8QFUQ01B1R6X No results 18335 JY8QFUQ01AHYYV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18336 JY8QFUQ01CNZMZ productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18337 JY8QFUQ01A34DZ productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + cctctggattcacctttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacgactgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctcgacagcacccccccgaagatgggaaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 18338 JY8QFUQ01B3HC3 productive (see comment) Homsap IGHV2-5*02 F 1134 96.31 235/244 nt 95.49 233/244 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcaCttttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccGaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18339 JY8QFUQ01CGPHQ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18340 JY8QFUQ01CLXF8 unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 850 88.43 191/216 nt 87.96 190/216 nt 8 7 X 8.7.X [2.17.38.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gtacacggcgggtccttcaaaggttactattggagctggatccgccagcCccccaggaaaggggctggagtggattggagaaatcgaccatagtggaaacaccaactacaacccgtccctcaagagtcgagtcaccgtgacagttgacacatccaagaaccaaatttccctgaatttgacctctgtgaccgccgcggacacggctatttattactgtgcgcgtatttcagcctttgaccagtggggccagggtaacccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 18341 JY8QFUQ01AZCNQ No results 18342 JY8QFUQ01CZ0AN unproductive Homsap IGHV3-48*02 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD1-1*01 F 3 8 8 X 8.8.X [1.17.38.11] CASGGKERLRSTTGLLSRHGRL# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggactcaccttcagcagctatagtatgaactgggtccgccaggctccagggaaggGggctggagtgggtttcatatattagtagtactagtagtaccataaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtgggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18343 JY8QFUQ01BXM61 unproductive Homsap IGHV3-7*01 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY#W out-of-frame - tctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactatttggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18344 JY8QFUQ01C76VU unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacgGgctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18345 JY8QFUQ01BNIBW productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18346 JY8QFUQ01APFLG unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 847 87.67 192/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKDKWYYDSSGFA##YLDYW out-of-frame + stop codons gcctctgggttcgccgtcagtagcaagttcatgagttgggtccgccaggctccagggaaggggctggagtgggtcgcagctatgagtggaggtggtggtggtgtgttctatgcagactccgtgaagggccggttcaccatctccagagacaattccaggaataccctgtatttgcaaatgaatagcctgagagccgaggacacggccgtatattattgtgcgaaagacaaatggtattatgatagtagtggttttgcaggactaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18347 JY8QFUQ01A1MJU productive (see comment) Homsap IGHV3-9*01 F 931 92.59 200/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'C' (1 nucleotides at position 143 to 143 in the user submitted sequence), (cause frameshift); tctggattcaccGtttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaagGggccgattcaccgtctcCcagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18348 JY8QFUQ01B5OF8 productive Homsap IGHV3-9*02 F 901 90.41 198/219 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD2-2*01 F 3 8 8 12 8.8.12 [2.17.38.11] CGKDMRPGGMDVLG in-frame - gcctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtcttgggggccagggggatcacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18349 JY8QFUQ01CI60Z productive Homsap IGHV3-11*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagatcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18350 JY8QFUQ01BRBCP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 999 95.85 208/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - ctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18351 JY8QFUQ01DVVPI productive (see comment) Homsap IGHV3-7*01 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [2.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaAaggggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggctgacggtgtcgtggaacctcagg 18352 JY8QFUQ01A1XCW No results 18353 JY8QFUQ01CCB8B productive (see comment) Homsap IGHV1-18*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CVRVIRTNWLDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcAaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgtgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18354 JY8QFUQ01CXKOE productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 997 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagntacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18355 JY8QFUQ01CG25J No results 18356 JY8QFUQ01CR2LQ productive Homsap IGHV3-7*01 F 851 88.07 192/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) cctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg 18357 JY8QFUQ01BOX9A productive (see comment) Homsap IGHV4-61*02 F (see comment) 740 81.9 181/221 nt 81.0 179/221 nt Homsap IGHJ4*03 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERAPSIDGVRELDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,90% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 35 of V-REGION: 'CT' (2 nucleotides at position 27 to 28 in the user submitted sequence), (cause frameshift); tctctggtggActccattaccagtggCTtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagcgggctccttcgattgacggagtgagagaacttgacttctggggccaggggaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18358 JY8QFUQ01B23SC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 947 92.31 204/221 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAREVIPTATYGMDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cagcgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18359 JY8QFUQ01CDCTW unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 358 86.32 82/95 nt 8 5 X 8.5.X [1.17.X.X] null + No rearrangement found cctctggattcagtttcagtagttatactatgaattgggtccgccaggctccagggaaggggctggagtggatttcatccattagcactggcagc 18360 JY8QFUQ01A0GVY productive Homsap IGHV3-9*01 F 810 86.18 187/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame + ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18361 JY8QFUQ01BFY8U productive Homsap IGHV3-48*02 F (see comment) 739 81.74 179/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18362 JY8QFUQ01BQUDF productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18363 JY8QFUQ01CJPZK productive Homsap IGHV4-61*03 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 10 7 12 10.7.12 [1.17.38.11] CTRHPKSNVEGDSW in-frame + tccctggtggctccgtcagcagtggtagttatttctggagctggatccggcagcccccagggcaggggctggaatggatcggttatgtctataacaatgggaacaccaattacaacccttccctcaagagtcgagtcaccatttctatagacacgtccgagaatcacgtctccctgaagctggcctctgtgaccgctgcggacacggccgtgtactactgtacgaggcacccgaagtctaatgtagagggtgactcctggggccagggagccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18364 JY8QFUQ01AVAG4 No results 18365 JY8QFUQ01DHQ86 productive (see comment) Homsap IGHV3-74*03 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'TC' (2 nucleotides at position 17 to 18 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacgttTCcacacctcctggatggcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18366 JY8QFUQ01B3AJ9 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + cctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18367 JY8QFUQ01AIGUU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame - Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 18368 JY8QFUQ01AV9D1 productive Homsap IGHV4-39*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 10 7 12 10.7.12 [1.17.38.11] CASVTTVSMRMKYW in-frame + tctctggtggctccatcagcagtgatagttactactggggctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatcgtgggagcacctattacaacccatccctcgagagtcggctcaccatgtcggtagacacgtccaggaacctcttctccctgaggctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagcgtgactacggtgtctatgaggatgaaatactggggccggggaaccccggtcaccgtctcctcagcatcccccgaccagccccaaggtcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18369 JY8QFUQ01BR9Z6 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F (see comment) 302 75.23 82/109 nt 8 10 X 8.10.X [1.17.X.X] null - No rearrangement found Low V-REGION identity (75,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcactttcagtgacgcctggatgagctgggtccgccagattccagggaaggggctggagtgggttggtcgtcgcatgcctggtccagggcttcttccccca 18370 JY8QFUQ01C8V2I unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1031 97.25 212/218 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD4-11*01 ORF 3 10 7 X 10.7.X [0.17.38.11] CARLDYTRYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaa 18371 JY8QFUQ01B801I No results 18372 JY8QFUQ01AXBDD unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 96 55.91 52/93 nt 54.84 51/93 nt 8 X X 8.X.X [17.6.X.X] null - No rearrangement found in FR1-IMGT, from codon 17 of V-REGION: 24 nucleotides (from position 107 in the user submitted sequence), (do not cause frameshift) gggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttgggggctggtcggggatgctgggggccgccggatccaactccagtagtaaccagtcatggagccaccagaga 18373 JY8QFUQ01BL763 productive Homsap IGHV1-2*02 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARGVDHRSVGYILW in-frame + cggatacactttgaacgactactatatgcactgggtgcgacaggcccctggacaagggtttgagtggatgggatggatcaaccccaacaatggtgacacaaaatattcacagaaatttcagggcagggtcaccatgaccagtgacacgttcagtagaacagcctacatggagctgaccagggtgaggtctgacgacacggccatttattattgtgcgaggggagtcgatcatcgtagtgttggatatatcctatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18374 JY8QFUQ01A5WAH unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgagcagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18375 JY8QFUQ01DWADM No results 18376 JY8QFUQ01C7CFD unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFGGSYNLVAY## out-of-frame + tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18377 JY8QFUQ01C9SXB productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame - ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18378 JY8QFUQ01CFSPR productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.37.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 201 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18379 JY8QFUQ01BZGM7 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) ggcctctggattcacCctttggttattatggcatgactggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18380 JY8QFUQ01DNP7Q productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARDMGSGRYFEPYDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccaaaccggtgacggtgtcgtggcaactca 18381 JY8QFUQ01AM5G1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 650 83.24 154/185 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD4-11*01 ORF 3 X 8 X X.8.X [X.15.38.11] DSRNPRV# out-of-frame - Low V-REGION identity (83,24% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtggggtccgccaggctccagggaaggggctggagtgggtctcagggctttgtggaagtgctcctaccacacactacgcagactccgtgaagggccggttcagcatctccagagacctctccaagaatgttctgtttctgcaaacgagcagcctgagagccgaggacacgaccgttttttctgactccagaaatcccagggtaggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18382 JY8QFUQ01CXLNY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + tctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18383 JY8QFUQ01BRBL7 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 773 84.65 182/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame + Low V-REGION identity (84,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgggggactccattagtggttactattggacgtggatccggcagaccccagggaagggactggagtggattggaaatgtccattacactgggagtaccaagtacagcccctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18384 JY8QFUQ01CX0IT No results 18385 JY8QFUQ01BIXBY productive (see comment) Homsap IGHV4-61*02 F 806 85.78 187/218 nt 84.4 184/218 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD4-23*01 ORF 2 9 7 17 9.7.17 [1.17.38.11] CARGECGVNCPYYNWYQHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'ATG' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 3 nucleotides (from position 24 in the user submitted sequence), (do not cause frameshift) tgtctggtggctccatcagcagtgATGattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacagtgtacaaccCcctccctcggggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgaggggtgagtgcggtgtcaactgcccctactacaactggtaccaacactggggcccgggaacccgggtcaccgtcacgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 18386 JY8QFUQ01B9IG9 unproductive (see comment) Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKDMVAGQGLLSR#FDHW out-of-frame + stop codons Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggttttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 18387 JY8QFUQ01BB5AY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18388 JY8QFUQ01BREZ1 unknown (see comment) Homsap IGHV3-7*01 F 856 88.13 193/219 nt 87.67 192/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); cctctggttttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctattTtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggctttattgacgtactggggccctgggaaccgcgggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaact 18389 JY8QFUQ01DGM8L productive (see comment) Homsap IGHV4-39*03 F 893 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift); tctccggtggctccatcaacagtagaaAattattattggggctggatccgccagccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18390 JY8QFUQ01BTGUH unproductive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 816 85.91 189/220 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [2.17.38.11] CVRDLNWS#FDSW out-of-frame - stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) agcctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtctttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18391 JY8QFUQ01DVFZP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 867 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) tccgaattcatccttgacagttatgccatgagttgggnccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18392 JY8QFUQ01DDHMO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 91.71 199/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18393 JY8QFUQ01DMQSJ unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CACYLIVMV#FDYW out-of-frame + ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttatttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18394 JY8QFUQ01B71U8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18395 JY8QFUQ01BT0YR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18396 JY8QFUQ01C9KK4 No results 18397 JY8QFUQ01CIKKB productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 524 89.31 117/131 nt 88.55 116/131 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 X 17 8.X.17 [1.3.31.11] CARDSVPRASEAAYHFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 39 in the user submitted sequence), (do not cause frameshift) cctctggattctccttcagaagttactctttccactggggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18398 JY8QFUQ01AVZ3U No results 18399 JY8QFUQ01A2E6C unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 18400 JY8QFUQ01BDTL8 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 846 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.16.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaagggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18401 JY8QFUQ01BO500 No results 18402 JY8QFUQ01BXZ5F No results 18403 JY8QFUQ01AHTIX productive (see comment) Homsap IGHV3-30*08 F 886 90.28 195/216 nt 88.89 192/216 nt Homsap IGHJ6*01 F 243 87.3 55/63 nt Homsap IGHD6-6*01 F 1 7 8 18 7.8.18 [2.16.38.11] CARDRPPSSTSYHYNGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) gcctctgcattcaccttcagtagtatgctttcactgggtccgccaggctccaggcggggactagagtggctgtctgttgtatcagcggatggaagtataaaatactacgcagactccgtgaagggccgattctccatctccagagacaactccaggaacacgctgtctctacaaatgaacagcctgagcgctgaagacacggctgtttattattgtgcgagagatcgccctccgagcagtacgtcctaccactacaacggaatggacgtctggggtcaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 18404 JY8QFUQ01CCO0P unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 165 80.39 41/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFMGVVVVPAAHNWFD#PW out-of-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18405 JY8QFUQ01CT185 productive Homsap IGHV3-33*04 F (see comment) 693 80.18 174/217 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release atttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag 18406 JY8QFUQ01CK21C productive Homsap IGHV3-72*01 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18407 JY8QFUQ01AKT55 No results 18408 JY8QFUQ01AX0TL productive (see comment) Homsap IGHV4-61*02 F 892 89.95 197/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18409 JY8QFUQ01C2RYU unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18410 JY8QFUQ01DOFXP No results 18411 JY8QFUQ01B1O2N productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame - cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18412 JY8QFUQ01BEAS9 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 18413 JY8QFUQ01BVECJ unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 112 64.52 40/62 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CGGQWQGS#YGINVW out-of-frame + stop codons cctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtggcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18414 JY8QFUQ01DUA6W productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 939 93.46 200/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 9 7 13 9.7.13 [X.16.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'CC' (2 nucleotides at position 71 to 72 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) gtggctccatcatcagagacagtgcctactggggctggatccgccagccccagggaaggggctggagtggCCtttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18415 JY8QFUQ01BBYMD No results 18416 JY8QFUQ01C7YWX No results 18417 JY8QFUQ01CM56B No results 18418 JY8QFUQ01CMHLV productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18419 JY8QFUQ01ATT4K productive (see comment) Homsap IGHV3-11*04 F (see comment) 875 90.57 192/212 nt 90.09 191/212 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01ATT4K ; 8 AA in Homsap_IGHV3-11*04) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccagctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18420 JY8QFUQ01B62FK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 18421 JY8QFUQ01CBXL5 No results 18422 JY8QFUQ01AYJKR productive Homsap IGHV1-69*02 F 930 92.52 198/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD1-26*01 F 3 8 8 18 8.8.18 [0.17.38.11] CATYSGTYGATSTGGAFDIW in-frame + tggaggcaccttcagcatctatactgtcaactgggtgcgacaggcccccggacaagggcttgagtggatgggaaggatcatctctctccttgatatagcgcactacgcacagaagttccagggcagagtcacgattgccgcggacaaatcctcgggcacagtctacctggagctgagcagcctgagatctgaggacacggccatgtattactgcgcgacatatagtgggacatacggcgcgacgagcacgggaggtgcttttgatatttggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18423 JY8QFUQ01C6S8D productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 856 88.13 193/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18424 JY8QFUQ01BVAO1 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt 77.52 169/218 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcattggtggaActtgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18425 JY8QFUQ01AVIDH No results 18426 JY8QFUQ01ASLIK productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'TT' (2 nucleotides at position 20 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttagTTtatcactgggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18427 JY8QFUQ01B7F74 No results 18428 JY8QFUQ01CUNM7 unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18429 JY8QFUQ01AW12K productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.16.38.11] CARDQSLGMPEAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggtccagggaaggggctggantgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18430 JY8QFUQ01CGODV unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18431 JY8QFUQ01DI18G productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactattggggctggatccggcagcCccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 18432 JY8QFUQ01A6FSC productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgctctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgacgagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18433 JY8QFUQ01BPAT4 No results 18434 JY8QFUQ01B1HC5 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccgag 18435 JY8QFUQ01B9P2E No results 18436 JY8QFUQ01CGPMH No results 18437 JY8QFUQ01B1ZOE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 924 91.36 201/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18438 JY8QFUQ01BSC7V productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18439 JY8QFUQ01B9FD1 No results 18440 JY8QFUQ01AMSQI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18441 JY8QFUQ01CI8F2 productive (see comment) Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18442 JY8QFUQ01AJOP1 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 18443 JY8QFUQ01BARSA productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccga 18444 JY8QFUQ01BJ7VH productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 18445 JY8QFUQ01BI347 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 824 86.7 189/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 9 7 15 9.7.15 [1.17.38.11] CTSREHAFSGQFTGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CGT' (3 nucleotides at position 23 to 25 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'TG' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); tgtctggtgtctccgtcaccagCGTcagtcactggtggacctgggtccgccaTGgcccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgcttttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18446 JY8QFUQ01C5RB9 No results 18447 JY8QFUQ01BXYQU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 18448 JY8QFUQ01CYLM9 unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGHLLGD#FDYW out-of-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgaccctttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 18449 JY8QFUQ01B3LQ2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18450 JY8QFUQ01CT2EE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18451 JY8QFUQ01BKNEI productive (see comment) Homsap IGHV3-9*01 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtAgggtctccggtatcactgggaatagtggttccataggcGtatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18452 JY8QFUQ01CM8GM No results 18453 JY8QFUQ01DR5LI unknown (see comment) Homsap IGHV3-7*01 F 1035 97.7 212/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 18454 JY8QFUQ01CN5UO productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18455 JY8QFUQ01BXRIG productive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 878 89.45 195/218 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [1.17.38.11] CARDKDVTARGTFDMW in-frame - tctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 18456 JY8QFUQ01A6M4U unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 18457 JY8QFUQ01CQQFN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 947 92.31 204/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARQSFDFAWQWQVDYYFEYW in-frame + tctctggtggctccgtcagcagtagcacttactactggggctggctccgccagtccccagggaaggctctggagtggattgggactatccatcatagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttgatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18458 JY8QFUQ01AYXXC No results 18459 JY8QFUQ01BOIBX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18460 JY8QFUQ01CYOK3 No results 18461 JY8QFUQ01C2SL2 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGASSDSWR#FDYW out-of-frame + stop codons cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagaggggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18462 JY8QFUQ01AOZ8H unproductive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAKGSFDSSGRPEAFDIW in-frame - stop codons in CDR2-IMGT at codon 63 of V-REGION: 'TG' (2 nucleotides at position 92 to 93 in the user submitted sequence), (cause frameshift); tggaggcaccttcagtagatatgctttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtccctctctttTGgttccataaaagtacgcacagaagtaccagggcagagccacgattaccgcggacgaatccacgagcacagtctacatggagctgagcagcctgagatctgacgacacggccatgtattactgtgcgaagggttcctttgatagtagtggtcgccctgaggcttttgatatctggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18463 JY8QFUQ01CY71J productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18464 JY8QFUQ01B4XTM productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 984 95.79 205/214 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-12*01 F 3 8 8 19 8.8.19 [0.17.38.11] CAREVSGYDLTVAGWWGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tggaggcaccttcagcagctatgctatcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcatccctatgtttggaaatccaaactacgcacagaagttccagggcagagtcacgataaccgcggacaagtccacgaacacagcctacttggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgagagaagttagtggctacgatttaacagtcgcggggtggtggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 18465 JY8QFUQ01BO261 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18466 JY8QFUQ01BE2FF productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 960 93.18 205/220 nt 92.73 204/220 nt Homsap IGHJ6*02 F (see comment) 211 82.26 51/62 nt Homsap IGHD1-20*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARDLRHYSYGFDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcaataattatatgatgaactgggtccgccaggctccggggaaggggctggagtgggtctcatCcctttaggagtagtgataattacatattctacgcagactcagtgaagggccgattcaccctctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgatgacacggctgtgtattactgtgcgagagacctgaggcattactcctacggtttcgacgtctggggccaagggacaacggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtatcgtggaactcag 18467 JY8QFUQ01BW7GR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 18468 JY8QFUQ01BUKLE productive Homsap IGHV3-30*07 F, or Homsap IGHV3-30*16 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYYFDSW in-frame + ctctggattcaccttcagtatttattctatgcattgggtccgccaggccccaggcaaggggctagagtgggtggcagttatatcacatgatggaactaataaatattactcagactccgtgaagggccgattcaccatctccagagacaattccaagagcgcgctgtatctgcagctgaacgtcctgagcgccgaggacacggctgtctatttctgtgcgagagattccgtacctcgggcgtcagaggctgcctactactttgactcttggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18469 JY8QFUQ01ANOBA productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 683 80.0 172/215 nt 79.53 171/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 99 in the user submitted sequence), (do not cause frameshift) cctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgacgagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 18470 JY8QFUQ01BR7IW unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-16*01 F 3 10 7 X 10.7.X [1.17.38.11] CARHPRPGTFDYLGGGWFD#PG out-of-frame - in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactgggcctggatccgccagcccccagggaaggggctggagtgccttgggagcatcttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccCttatccgttgacacttccaagaaccagttctccctgaagctgagctctgtggccgccgcagacacggctgtgtattactgtgcgagacatccccgcccgggaacttttgactacttaggggggggttggttcgacccctgggggccagggaattccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18471 JY8QFUQ01AB2ZQ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18472 JY8QFUQ01CZ2LW productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 821 85.97 190/221 nt 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQWLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgaggTaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaatggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18473 JY8QFUQ01CNI6X productive Homsap IGHV3-9*02 F 896 90.37 197/218 nt Homsap IGHJ6*02 F 172 78.57 44/56 nt Homsap IGHD1-14*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + cctccggattcacctctggaaagtatgccatgcactgggtccggcaagctccagggaaggacctggagtgggtctcaggcttgggtttggataatggtaggatagactacgcggactctgtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccaggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18474 JY8QFUQ01AX5HQ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 554 92.97 119/128 nt 92.19 118/128 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 X 16 8.X.16 [2.6.26.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18475 JY8QFUQ01CLJ2N productive Homsap IGHV1-3*01 F (see comment) 351 73.53 100/136 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 X 7 14 X.7.14 [X.X.38.11] CARGRYDSSGRGHEYW in-frame - Low V-REGION identity (73,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacaccttcaccagtttcagtatccattggaagttccaggacagactcaccattactagagacacatccgcgagcacagcctacatggacctgagcagcctgagatctgaagacacggctgtctattactgtgcgagagggcgctatgatagtagtggtcgtggccatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18476 JY8QFUQ01AKPS7 productive (see comment) Homsap IGHV4-34*06 F (see comment) 701 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 14 8.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tccatggtgggtccctcaGggggttacccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 18477 JY8QFUQ01BX9JE productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame + ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgtctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 18478 JY8QFUQ01B2HDD productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag 18479 JY8QFUQ01CBRXW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.37.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 178 in the user submitted sequence), (cause frameshift) agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactcgtgagggccgagttcaccatctccagagacaacgccaagaacacgctatatcttcaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18480 JY8QFUQ01BO776 productive Homsap IGHV3-9*01 F 891 90.32 196/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 8 8 26 8.8.26 [1.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcacctttgatgattttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18481 JY8QFUQ01B35EB productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 918 91.71 199/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame + ctctggatttaccttcagtggctatggcatgcactgggtccgccaggctccaggcaagggcctggagtgggtgacagttgtttcatatgatggaagtattaagaattatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18482 JY8QFUQ01DD88U productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcaatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 18483 JY8QFUQ01ASA25 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 440 78.87 112/142 nt 8 8 X 8.8.X [1.17.13.X] null + No rearrangement found Low V-REGION identity (78,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttc 18484 JY8QFUQ01BPAXT unknown (see comment) Homsap IGHV3-11*01 F (see comment) 468 68.2 148/217 nt 67.74 147/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (68,20% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaGgtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18485 JY8QFUQ01BGNSE productive (see comment) Homsap IGHV4-55*03 P (see comment) 613 75.69 165/218 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARESRNSFGGPTGLDSW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01BGNSE ; 9 AA in Homsap_IGHV4-55*03), and low V-REGION identity (75,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctctgttgacgccataagcgacctcggttatttctgggcctgggtccgccagcccgccgcgaagggactggagtggatcggacatgcccttggtgatggatataccgaatacaaccccgccctagagagtcgaatcaccgtgtcagtggacaagtccaagaaccagttttccctgacgttggagtccgtgaccgccgcagacacggccacttatttctgtgcgagggaaagtcggaattcatttggcgggccgacaggccttgattcctggggccagggaattgtggtcatcgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtcatcgcctgcctggtccagggcttct 18486 JY8QFUQ01ADG23 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 790 84.23 187/222 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [2.17.38.11] CARILDGYFFDPW in-frame - Low V-REGION identity (84,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gtctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18487 JY8QFUQ01C9T87 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18488 JY8QFUQ01BURMR productive Homsap IGHV3-11*01 F (see comment) 756 83.41 181/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-8*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGRGRTNSPVDLW in-frame + Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccctcagtgactacagtatgagttgggtccgccaggctccagggaaggggctggagtgggtctcatacatcagccgaagtggaagtaatgtggaaactgcggactctgtgaggggccgattcaccgcctccagggacaccgccaataattcactgtttctgcggatgaatagcctgacagtcgaggacacggccctctattactgtgcgagaggtagggggcgcactaatagtccagttgacctctggggccagggaacccaggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctagtccagggcttcttccccca 18489 JY8QFUQ01CFZQK productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaatagaaAactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18490 JY8QFUQ01CG395 productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 820 86.3 189/219 nt 85.39 187/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [1.17.38.11] CAHFGPQEHFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'G' (1 nucleotides at position 191 to 191 in the user submitted sequence), (cause frameshift); tctggattctcactcagcaccaatggaatgggtgtgggttggatccgccagTcccccgggagaggccccagactggcccgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgGggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18491 JY8QFUQ01CZO1G productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F 472 93.52 101/108 nt 92.59 100/108 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 X 15 8.X.15 [1.15.11.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 106 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) ctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttaaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18492 JY8QFUQ01BGUDP No results 18493 JY8QFUQ01BDVNF productive (see comment) Homsap IGHV4-61*02 F 895 90.74 196/216 nt 87.04 188/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [2.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 25 to 30 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 120 to 121 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 222 to 222 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) tgtctccggtggctGccatcagtaCTGGTTattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaaACcccctccctccCagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtaCtttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18494 JY8QFUQ01CNCM5 productive (see comment) Homsap IGHV2-5*02 F 1012 90.57 221/244 nt 88.93 217/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 7 18 10.7.18 [9.17.38.11] CAHNSLYDRNGYYLTYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'TG' (2 nucleotides at position 29 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 155 to 155 in the user submitted sequence), (cause frameshift); aaccctcacactgacctgcaacctctctTGggggtctcactcagcagtcgtggantgggtgtgggctggatccgtcaggccccaggaAaaggccctggagtggcttgccctcattgaCttgggatgatgacaagcgctatagtccatctctaaaCggggaggctcaccatcaccagggacacctccacaggccaggtggtcctcacaatgaccaacatgcaccctgtggacacagccacatattactgtgcacacaacagtctctatgataggaatggctattatttgacgtactttgatcactggggccagggagccctggtccccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18495 JY8QFUQ01B289X productive (see comment) Homsap IGHV3-7*03 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [0.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); cggattcacttttagtgactattggatgagttgggtccgccaggctccagGggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18496 JY8QFUQ01CU9FN productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 18497 JY8QFUQ01CJDBG productive Homsap IGHV3-66*02 F 840 88.32 189/214 nt Homsap IGHJ6*02 F (see comment) 197 80.33 49/61 nt Homsap IGHD2-8*01 F 3 8 7 11 8.7.11 [1.17.38.11] CASHLMVYALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccgtcagtggcaagtacatgagctgggtccgccaggctccagggcagggactggagtgggtctcagttatctatagtactggtagtacatactacgcagattccgtgaaagggcggttcaccatctccagagacagttccaacaacactctatatcttcaaatttacggcctgagagctgacgacacggctacttactactgtgcgagtcacttaatggtgtatgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18498 JY8QFUQ01A4CKC productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattggGgtatatctattacagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccagaaccggtgacggtgtcgtggaactcag 18499 JY8QFUQ01BROL6 No results 18500 JY8QFUQ01B2D9Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18501 JY8QFUQ01A9JOS productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame + ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18502 JY8QFUQ01DHHR1 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccCgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18503 JY8QFUQ01BHY4J unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 472 71.07 140/197 nt 8 7 X 8.7.X [1.17.32.X] null + No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BHY4J ; 8 AA in Homsap_IGHV3-11*01), and low V-REGION identity (71,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18504 JY8QFUQ01CUS2N productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGXYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtnattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagcccagatgggaacgtggtctcgcctgcctggtccagggcttcttcccc 18505 JY8QFUQ01B33G7 No results 18506 JY8QFUQ01CSANS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.37.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 94 of V-REGION: 1 nucleotides (from position 185 in the user submitted sequence), (cause frameshift) ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18507 JY8QFUQ01CDSSD productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctggattcacctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18508 JY8QFUQ01BVHZS productive (see comment) Homsap IGHV3-11*01 F (see comment) 694 79.91 175/219 nt 79.45 174/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-25*01 F 2 8 8 11 8.8.11 [2.17.38.11] CVRDRSRGIADPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); acgtctggattcaccttcactgactattggatgagttgggtgcgcctgAgccccagggaagggtctagaatgggtttcgttcataagtggaagtggcaatagtgtctggtatgcagactctgtgaagggccgattcattatctccagagacaacgccaaaaatttagtctttttggacatgaacagcctgagagtcgaggactcggccatgtattattgtgtgagagaccgcagcaggggaatagcagatccttggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18509 JY8QFUQ01CBMMN productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcg 18510 JY8QFUQ01ANRK5 productive Homsap IGHV3-7*01 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18511 JY8QFUQ01AQ2VK productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ1*01 F 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKDHKSGWSLQDW in-frame + ctctggattcacctttaatatgtattggatgtactgggtccgccaggctccagggaaggggctggagtgggtggccaagataggcctagatggaagtcaaaaatactatgtggactctgtgaagggccgcttgaccatctccagagacaacgccaagaactcactatatctccaaatgaatagcctgagagccgaggacacgggtgtatactactgtgcgaaggatcataaaagtggctggagcctccaggattggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttcccccgtggcgccctgctccaggagcactccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18512 JY8QFUQ01C8FEX productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctattcggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18513 JY8QFUQ01BRVR1 unproductive (see comment) Homsap IGHV3-48*01 F 1071 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + stop codons ctctggattcaccttcagtagctatagcatgaactgagtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18514 JY8QFUQ01BX1X7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 825 86.36 190/220 nt 85.0 187/220 nt Homsap IGHJ6*02 F 187 79.66 47/59 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARRDSDFRMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift); ggtgtctggatatgactttagcagAattttggatcgcctgggtgcgccagatgcccgggaAaaggcctggagtggattggaatcatctatcctagtgactctgatacgagatacagtcccaccttccaaggccaggtcattatctcagccgacaagtccctcagtaccgcctacctacttTtttagcagtctgagggcctcggacaccgccatgtatttttgtgcgagacgtgattccgacttccgtatggacgtctggggccaggggaccacggtcaccgtgtctccaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18515 JY8QFUQ01AZPOK productive (see comment) Homsap IGHV3-66*02 F 898 91.55 195/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 2 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18516 JY8QFUQ01BZ9RI productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt Homsap IGHJ4*02 F 184 90.91 40/44 nt 8 10 6 8.10.6 [1.17.38.11] CTTESAYW in-frame + tctctgcattcactttcagtaatgcctggatgacctgggtccgccaggctccagggaaggggctggagtggcttggccgtattaaaaggaaagttgatggtgagacaacagactacgctgcatccgtgaagggcagattcaccatctggagagatgactcaaaaaacactctatatctgcaaatgaacagcctggaacccgaggacacagccgtatattattgtaccactgaatctgcctattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18517 JY8QFUQ01C3KOZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGGG# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggctctggattcacttttagcagccatatgatgacttgggtccgccaggctccagggaaggGggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggggccagggagcccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 18518 JY8QFUQ01ADK2S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 18519 JY8QFUQ01DHQO3 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 18520 JY8QFUQ01DMU8Z productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18521 JY8QFUQ01CU00E unproductive Homsap IGHV3-48*01 F 954 93.55 203/217 nt Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSRHSASGSYSDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactgggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18522 JY8QFUQ01B7RCO unknown (see comment) Homsap IGHV2-26*01 F (see comment) 792 80.33 196/244 nt 79.51 194/244 nt 10 7 X 10.7.X [9.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (80,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR1-IMGT at codon 25 of V-REGION: 'CTCTGAG' (7 nucleotides at position 25 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcatcgtCTCTGAGctctgagttctcactcaacaatgctagaaagggtgtgagctggatccgtcagcCccccagggaaggccctggagtggcttgcacacattttttcgaatgacgaaaagtcctacaacacatctctgaagaccaggctcaccatctccagggacacctccaaaagccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18523 JY8QFUQ01AXFJF No results 18524 JY8QFUQ01CZG88 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 880 90.61 193/213 nt 89.67 191/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 6 8 12 6.8.12 [1.17.38.11] CVRDGQRGYDNDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 5 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gccctggattcaacaaaatatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaaActattagtggtagtggtggtaggacatactacgcagactccgtgaagggccgattcaccatctccagagacaatgccaggaactcactttttctgcaaatggacagcctgagagccgaagacacggctgtttattattgtgtgagagatgggcaaaggggctacgataatgactgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18525 JY8QFUQ01AGZLZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18526 JY8QFUQ01BQHSW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtgggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 18527 JY8QFUQ01CD7C8 productive Homsap IGHV3-7*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - tgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18528 JY8QFUQ01BJ2NQ productive (see comment) Homsap IGHV3-72*01 F 948 91.93 205/223 nt 91.03 203/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 57 to 59 in the user submitted sequence), (do not cause frameshift); ctctggattcaccttaagtgatcactacatggGactgggtccgccaggctccaaggGAAagggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18529 JY8QFUQ01A0N2L unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccacccccaagatgggaacgtggttgtcgcatgcctggtccagggcttcttccccca 18530 JY8QFUQ01A4H4X unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 817 85.59 190/222 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [2.17.38.11] CVRLSDYYDTSGYAES## out-of-frame - gtctctggtgactccatcactaatagtcgttacttctgggcctggatccgtcagccccacgggaagggactggagtggattgggagcatctattacactgcgcaaaccaactccaacccgtccctcaagaatcgagtctccatatccatagacacgtccaagaatcagttcttcctgagtctcacctctgtgaccgccgcagattcggctgtgtattattgtgtgagactgagcgattattatgatactagtggttatgcggaatcctgggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18531 JY8QFUQ01ALZSP productive (see comment) Homsap IGHV3-9*01 F (see comment) 784 84.47 185/219 nt 83.56 183/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); gcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggaGgtgggtcgcgggcaGtcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18532 JY8QFUQ01BITA5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 804 86.45 185/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - ctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18533 JY8QFUQ01CS3HY productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.37.11] CTTGGGTNYYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 160 in the user submitted sequence), (cause frameshift) tctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18534 JY8QFUQ01DMKS5 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 853 89.2 190/213 nt 88.26 188/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [0.17.38.11] CTRDIGGRYSYW in-frame - stop codons in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) cggattcaccttagtagtttctggatgcactgggtccgccaagttccaggGGgagggaactggtgtgagtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18535 JY8QFUQ01CBN73 productive (see comment) Homsap IGHV3-72*01 F (see comment) 804 84.0 189/225 nt 82.67 186/225 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-7*01 F 1 8 10 18 8.10.18 [2.17.38.11] CARGITGTTPPYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GGAAA' (5 nucleotides at position 59 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'GGTTCGGCA' (9 nucleotides at position 80 to 88 in the user submitted sequence), (do not cause frameshift); gtcgtctggatcaccttcagngaccactacatgGgactgggtccgccagcccccaaggGGAAAaggggnttggaggtggGGTTCGGCAccggtagtaggaaaacaaaagctggcagttacaccacagtatacgccgcgtctgtgaaaggcagattcagcgtctctagagatgattcccagaagtcactgtatctgcaaatgaacggcctgaaaaccgaggacacggccgtgtattattgtgctagagggataactggaactacgccgccctattactattacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18536 JY8QFUQ01ASRCX No results 18537 JY8QFUQ01AF07V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18538 JY8QFUQ01CKFL6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18539 JY8QFUQ01BIK4E productive (see comment) Homsap IGHV3-48*01 F 894 91.12 195/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.16.38.11] CAKGHSTGSWLIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 2 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttataccatgaactgggcccgccaggctccagggagggcgtggagtggtgcattcatcggcagtacaactgataccgtatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccgagaactcactgtttctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgaaagggcattctactggcagctggttgattgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18540 JY8QFUQ01DCQ77 No results 18541 JY8QFUQ01CZ00U productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgcacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 18542 JY8QFUQ01DEK3I productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttataGgcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18543 JY8QFUQ01BQSL5 productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggagccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18544 JY8QFUQ01A1Q3N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGSYRLQLESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagctatggcatgagttgggtccgccagtctccaaataagggactggagtgggtcgcaggcattagtgcaaatggtggcagtataaattatctggacgccgtgaagggccggtttatcatctctagagacaattccaagaacacgttgtatctgcaaatggacagcctgacagtcgaggacacggccgtttattactgtgtgaaagatcgtgattttctttgggggagctatcgtcttcaacttgaatcttggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 18545 JY8QFUQ01ADAT4 productive Homsap IGHV2-5*02 F, or Homsap IGHV2-5*04 F 972 88.93 217/244 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 2 10 7 13 10.7.13 [9.17.38.11] CARKYGSSTNGFDPW in-frame + gaccctcacgctgacctgcacgttctctggattctcactcaacacacagggaatgggcgtggactggatccgtcagcccccaggaaaggccctagagtggctaggcctcatttactgggatgatgatacgcgctacagcccatctctgaggaacaggctcagcatcaccaaggacacttccaaaaaccaggtggtcctgacactgaccaacgtggacgctatggacacaggcacatattattgtgcgcgcaaatatggcagcagtacgaacggattcgacccctggggccagggactcctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttnttcccccc 18546 JY8QFUQ01ARA3B productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 18547 JY8QFUQ01B1B77 productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGKGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtaagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcatggaactca 18548 JY8QFUQ01CCP6E productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccc 18549 JY8QFUQ01CIOCG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [2.16.38.11] CARDTLEVVSNMDDAFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtcgttGatagcatgaactgggtccgccaggctcgagggaagggcttgagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18550 JY8QFUQ01BSC6G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame + cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18551 JY8QFUQ01BV8Y2 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18552 JY8QFUQ01C060D unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 940 93.06 201/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + stop codons tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgtaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18553 JY8QFUQ01CCQXW productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatggatccgccagcAccccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18554 JY8QFUQ01AE5FV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.17.38.11] CAKEEGATGVYYVDHW in-frame - gcctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18555 JY8QFUQ01DIZBB productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) ggcctctggatcaccctttggttattGatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18556 JY8QFUQ01COTUF unproductive Homsap IGHV3-48*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [0.17.38.11] CARDMIIFGEP#DNW out-of-frame - tggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18557 JY8QFUQ01BPLX0 No results 18558 JY8QFUQ01DJLNZ productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgccatggcctggtccagggcttcttcccc 18559 JY8QFUQ01B4NSQ No results 18560 JY8QFUQ01BKVFD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18561 JY8QFUQ01CS6IW productive (see comment) Homsap IGHV3-48*01 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CTRQTGNYYYFGVDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); gcctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggAaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18562 JY8QFUQ01AZI1W unproductive Homsap IGHV3-9*01 F 848 89.15 189/212 nt 88.68 188/212 nt Homsap IGHJ1*01 F (see comment) 80 61.54 32/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.36.11] CSKDRYHFDSSQHAMDVW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 82 of V-REGION: 6 nucleotides (from position 150 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttggtgactttgccatgcactgggtccgacaacctccagggaagggcctggagtgggtcgcgactattagttggaggaatattagtagaggctatgcggactctgtgaagggccgattcaccatctccagagacaagaactccctgtacttgcaaatgaacactctgagatcagaggacacggccttctattattgttcaaaagacaggtatcattttgatagtagtcagcacgctatggacgtctgggggccaagggacccccggtcaccgttttctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 18563 JY8QFUQ01DBASA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 88 49.73 92/185 nt 8 7 X 8.7.X [1.17.28.X] null + No rearrangement found stop codons cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 18564 JY8QFUQ01BRZBI productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18565 JY8QFUQ01AIIJ3 No results 18566 JY8QFUQ01B9KPG No results 18567 JY8QFUQ01DMVKI productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1011 96.74 208/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'TG' (2 nucleotides at position 95 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'AC' (2 nucleotides at position 114 to 115 in the user submitted sequence), (cause frameshift); tctctggtggctGccatcagtagCttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaaanTGgggagcaccaactacaaACcccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18568 JY8QFUQ01DSZT6 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKK*GVGDG##WYFDFW out-of-frame + stop codons in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaaatagggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18569 JY8QFUQ01DEOJZ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gtctctgtgactccatcagtagtGactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18570 JY8QFUQ01AYC76 productive Homsap IGHV3-NL1*01 F (see comment) 330 73.08 95/130 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 X 5 17 X.5.17 [X.X.38.11] CARDSVPRASEAAYHFDYW in-frame - Low V-REGION identity (73,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattctccttcagaagttactctttccactggggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18571 JY8QFUQ01BHAGC unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 134 63.29 50/79 nt 8 X X 8.X.X [1.17.X.X] null + No rearrangement found ctctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18572 JY8QFUQ01BB8RF unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGDCLL*WW*#CYDPW out-of-frame - stop codons cctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccagggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18573 JY8QFUQ01BKE2G unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttaCctggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaagggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18574 JY8QFUQ01AH8RP No results 18575 JY8QFUQ01A4BLB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactaCtcaaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18576 JY8QFUQ01ATLUC unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 730 79.91 183/229 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [5.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - stop codons Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggactccatttccagtacctagttaattgacttggggctgggtccgccancccccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18577 JY8QFUQ01A7PRV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18578 JY8QFUQ01CVGHI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 8 13 8.8.13 [1.17.38.11] CAKHRLVTSNHFASW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtgatagcacaaactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaacaacacgctatatctgcagatgaacagcctgagagccgaggacccggccgtgtattactgtgcgaaacaccgtttggtgaccagcaaccactttgcctcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18579 JY8QFUQ01CVBL6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagCttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaAaagtgggagcaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18580 JY8QFUQ01CYCK8 productive (see comment) Homsap IGHV3-7*01 F 1000 95.43 209/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.16.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) gggctctggattcagctttagttactattGggatgagctgggtccgccaggctccagggaaTggggctggagtggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18581 JY8QFUQ01CPAOQ productive (see comment) Homsap IGHV3-7*03 F 941 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-7*01 F 1 8 8 16 8.8.16 [1.17.38.11] CATARLGPGTSIYLTAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); cctctggattcacctttggtagctattggatgggcCtgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgcgagtcgaggacacgggcatttacttctgcgcgacagcccgtctcgggcctggaacttcgatttatctcacggcctactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18582 JY8QFUQ01AIWG6 unknown (see comment) Homsap IGHV3-64*02 F, or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 99 52.59 71/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tctctggattcagcttcagtgactatggcatgggctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18583 JY8QFUQ01B26R3 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 857 89.2 190/213 nt 88.73 189/213 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); tcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagGactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgcgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18584 JY8QFUQ01ATAYA No results 18585 JY8QFUQ01BBPPK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18586 JY8QFUQ01B92LW unproductive (see comment) Homsap IGHV3-7*01 F 955 93.15 204/219 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [2.17.38.11] CVRRGW*RAD#DAFDIW out-of-frame - stop codons gcctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggatggtagcgggcagatatgatgcttttgatatctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18587 JY8QFUQ01DQ5GC productive (see comment) Homsap IGHV3-66*02 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD3-16*01 F 2 8 7 13 8.7.13 [1.16.38.11] CAALHDPPWGWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcagcgtcaacaacaactacatgaactgggtccgcctggctccagggaaggtctggagtgggtctcagttatttatagaggtggtaatacattctacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacactttgtatcttcaaatgaacagtctgacaactgaggacacggctgtgtactattgtgcggccctccacgaccctccttggggttggctcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18588 JY8QFUQ01B1SZE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 386 84.91 90/106 nt 83.96 89/106 nt 8 8 X 8.8.X [1.16.1.X] null - No rearrangement found Low V-REGION identity (84,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 2 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) gctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggggctggagtgggtctcagccattagtggcagtggtagtcggacatatt 18589 JY8QFUQ01CD2BO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.67 198/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18590 JY8QFUQ01CFKOA No results 18591 JY8QFUQ01CKHQ3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18592 JY8QFUQ01CX8CY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18593 JY8QFUQ01CRD7Z productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaAaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18594 JY8QFUQ01DBZ9Q unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 3 10 7 X 10.7.X [1.17.38.11] CVRPDNYFGSGEC#WMDPW out-of-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcgggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18595 JY8QFUQ01AGER9 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18596 JY8QFUQ01CKS7U productive Homsap IGHV3-48*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARVENYSDSGGSFDYW in-frame - cctctggattcaccttcagtagctatagcatgaattgggtccgccaggctccagggaagggactggagtgggtttcatacattagtggaagtagtaataccatgtactacgcagactctgtgaagggccgattcaccatctccagagacaatgcccagaattcactacatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagtggaaaattactctgatagtggtggttcgtttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18597 JY8QFUQ01CLEF5 unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 1 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGRYDENYYELDF## out-of-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18598 JY8QFUQ01AA38B productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30-3*03 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDYW in-frame + ctctggattctccgtttccagctatgctctgcactgggtccgccagtctcccggcaaggggctggagtgggtggcggctatttcatatgatggaagtaaaatatattatgcagactccgtgaggggccgcttctccatctccagagacacttccaggaacactctgcatttgcaaatggacggcctgagagctgacgacacggctacatattactgtgcgagagacagacggccacttagggagtttgactattggggccagggaaccctggtcgccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg 18599 JY8QFUQ01CAH1L productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18600 JY8QFUQ01CQL7O No results 18601 JY8QFUQ01BLCSS unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + stop codons ctctggattcaccttcagtagttataacatgcactgagtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18602 JY8QFUQ01B5BBS productive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + cctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 18603 JY8QFUQ01B1S6W productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD4-11*01 ORF 2 8 7 17 8.7.17 [1.17.38.11] CARVGRSVGYSDSGWFDPW in-frame + tctctggtggctccatgagtagttactactggaactggattcggcagcccccagggaagggactggagtggattgggtatatctattacactgggatcaccaactacaatccctccctcaagagtcgagtcaccatgtcaatagacacgtccaggaagcagttctccctgaccctgacctctgtgaccgctgcggacacggccgtctatttctgtgcgagagtcggccggagtgtgggctacagtgactctgggtggttcgacccctggggccagggaaccctggtaccgtctcctacccatcccgaccagccccaaggtcttcccgctgagccctctgcagcacccgagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccccag 18604 JY8QFUQ01C6ZKX productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18605 JY8QFUQ01CB4CV unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccaggggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttcccccca 18606 JY8QFUQ01B8ABJ productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGGTVTAGGPRIVFGYW in-frame + tggctacaccttcaccgactactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctgacggtggtagcacaaagtatgcacagaaatttcagggcagggtcgccgtgaccagggacacgtcaattagcacagcctacattgaggtgaccagactgacatctgacgacacggccgtgtattattgtgccagaggagggactgtgacagcaggtggtcctcgtattgtctttgggtactggggccagggaacgttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18607 JY8QFUQ01CRFE1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 630 93.1 135/145 nt 92.41 134/145 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 7 16 8.7.16 [1.17.14.11] CARGPVGISESVNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 73 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagaggtccggttgggataagtgaaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18608 JY8QFUQ01CAWSO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccca 18609 JY8QFUQ01CM1KM productive (see comment) Homsap IGHV3-23*05 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 18610 JY8QFUQ01AGBNN productive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tctggtttcaccGttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18611 JY8QFUQ01BPY9Q unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1009 95.89 210/219 nt 94.98 208/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDNYGDY## out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 95 to 96 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaagGgggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18612 JY8QFUQ01AJOX0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18613 JY8QFUQ01DCN0X unknown (see comment) Homsap IGHV3-72*01 F 106 53.44 70/131 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18614 JY8QFUQ01B3UPR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 805 85.71 186/217 nt 84.33 183/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tccgggagttcaccttagtagtttctggGatncactggggtccgcaagttccCAaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18615 JY8QFUQ01BNN3E productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 164 81.63 40/49 nt Homsap IGHD2-21*02 F 3 8 8 7 8.8.7 [2.17.38.11] CARMTDDFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gtctctggattcaccttcagtagctataGgcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagcagtagcaccataaaatacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagaatgacagacgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 18616 JY8QFUQ01CZ0RM productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18617 JY8QFUQ01BUDBO No results 18618 JY8QFUQ01BBY90 No results 18619 JY8QFUQ01DROLK No results 18620 JY8QFUQ01ANFIE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 850 88.02 191/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKCKAPGKVDWFDPW in-frame - ctctggattcacctttagcggctatnccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcaactagtactactgatggagctggcccatactacgcagactccgtgaggggccggttcaccgtcttcagagacaattccaagaacactctgtatctacaaatggacaccctgagagccgacgacacggccatgtattactgtgcgaaatgtaaagcgcctggtaaggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18621 JY8QFUQ01ANNVX unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLPFIVVVTGAFLGHFDY## out-of-frame + ttctggatacatctttaccaattactggctcggctgggtgcgccagatgcccggcaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgtttttgggacactttgactattggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18622 JY8QFUQ01ABD4U productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18623 JY8QFUQ01CPF88 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18624 JY8QFUQ01DJ7CR No results 18625 JY8QFUQ01B37PC productive (see comment) Homsap IGHV4-61*02 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [2.17.38.11] CTNGGHYYGSEFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'GCAGTG' (6 nucleotides at position 20 to 25 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcaGCAGTGgcagttactactggagctggattcggcagcccgccgggaagggactggagtggattgggcgtttgcataccagtgggggcCaccgactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtactaatggcgggcattactatggttcggagtttgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18626 JY8QFUQ01BDXFT No results 18627 JY8QFUQ01AWE6F productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt 86.24 188/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccGggggaagggactggtgtGgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18628 JY8QFUQ01CNIOH productive (see comment) Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt 82.81 183/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaAattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc 18629 JY8QFUQ01DXB5W No results 18630 JY8QFUQ01ARQX3 unproductive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAGAEAGL#DYW out-of-frame + ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcgggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccccttggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18631 JY8QFUQ01CDUAP productive (see comment) Homsap IGHV3-48*03 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagttcttatgccatgaactgggtccgctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18632 JY8QFUQ01CQJZD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18633 JY8QFUQ01AQBPX unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 18634 JY8QFUQ01CTDAY No results 18635 JY8QFUQ01BNNYX productive (see comment) Homsap IGHV2-5*02 F 1116 95.49 233/244 nt 94.67 231/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CAHIRAELSTSCHAFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 185 to 185 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcacttgtttattgggatgatgataagcgctacagctcatctctgaagagcagactcaccatcaccaagGgacacctccaaAaaaccaggtggtccttacaatgactaacatggaccctatggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18636 JY8QFUQ01CA1TB unproductive Homsap IGHV3-48*02 F 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [2.17.37.11] CARDHWDNNGYHWFD#PG out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 89 of V-REGION: 3 nucleotides (from position 172 in the user submitted sequence), (do not cause frameshift) gcctctggaAttcgccctcagtagttataccatgaactgggtccgccaggccccaggcaaggggctggagtgggtttcacacacaagtagcagcgttagcaacatgttctacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatcaaatgaacagcctgagagacgaggacacggctgtatattactgtgcgagagatcattgggacaacaatggttatcactggttcgacccctggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccgaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18637 JY8QFUQ01BDV2Y productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 867 89.72 192/214 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [0.17.38.11] CARVGGDDDDGYYVGEDAMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tggatacaccttccccgaccactatgtacactgggtgcgacaggcccctggacaagggcttgagtggatgggacggatcagccctaacactggcggcgcacactatggacagaggtttcagggcagggtcaccatgaccagggacacgtccatcaccacagtctacatggaattgagcaggctgagtccggatgacacggccgtgtattattgtgcgagagttgggggagatgatgatgacggttactatgtcggggaggacgctatggacgtctggggccaggggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18638 JY8QFUQ01CSHAA unproductive Homsap IGHV4-4*07 F 905 92.82 194/209 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD3-22*01 F 3 7 7 X 7.7.X [X.17.38.11] CARGKDYYDSTGSLEDGLDI## out-of-frame + gtggctccctcagtacttactactggaactgggtccggcagcccgccgggaagggactggagtggattgggcgtaaatatcccagtggggacaccaactataatccctccctcaaaagtcgagtcaccatgtcactagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagggaaggattactatgatagtactggttccctcgaggatggtcttgatatctgggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18639 JY8QFUQ01AVJRE productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18640 JY8QFUQ01CABL5 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 962 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARGRMVRGVTLIWWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); tgtctggtgggtccttcagtacttactactgGgacctggatccgccagcCccccagggaaggggctggagtggattggggaaatcagtcatagtggaagcaccaactacaacccgtccctcaagagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgaaactgatctctgttatcgccgcggacacggctgtgtattattgtgcgagaggcaggatggttcggggagttaccctgatctggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18641 JY8QFUQ01CJESL No results 18642 JY8QFUQ01CF5D6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [2.17.38.11] CTREVGATDYW in-frame - gcctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18643 JY8QFUQ01CLSXJ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 302 96.88 62/64 nt 8 X X 8.X.X [1.12.X.X] null - No rearrangement found tctggattcaccttcagcagctatagaatgaactgggtccgccaggctccagggaaggggctgg 18644 JY8QFUQ01C2508 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 113 50.48 105/208 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18645 JY8QFUQ01CXQH0 productive Homsap IGHV3-66*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18646 JY8QFUQ01CGT1P productive Homsap IGHV3-23*03 F (see comment) 813 86.92 186/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 2 8 7 11 8.7.11 [1.17.38.11] CARDRQSWGIDSW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CGT1P ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagcggctatgccatggcttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggtgacacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaatacactttttcttcaaatgacttccctgagagtcgaagatacggccatttattactgtgcgagagatcgtcagagctgggggattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18647 JY8QFUQ01DCUSM productive (see comment) Homsap IGHV3-66*02 F 898 91.55 195/213 nt 91.08 194/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18648 JY8QFUQ01CIXUH productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18649 JY8QFUQ01CJ2Q1 unknown (see comment) Homsap IGHV3-7*01 F 909 91.24 198/217 nt 90.78 197/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggGccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccccatttacggtgactactgggaaggacgcctactggggcccagggcaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaa 18650 JY8QFUQ01CIGXV productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18651 JY8QFUQ01BR5P2 productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame - ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggagggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18652 JY8QFUQ01B8LO4 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18653 JY8QFUQ01AV5VY productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 914 91.28 199/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 7 16 8.7.16 [2.17.38.11] CARDEIPWDTIEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) gcctctggattcaccGttcactacatattccatgcactgggtccgccaAggctccaggcaaggggctagaatgggtggcagttatatcatatgatgggaaaaaaaatcttatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtgtattactgtgccagagatgagatcccttgggatacaatagagtactactttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18654 JY8QFUQ01AMACY No results 18655 JY8QFUQ01DW0ED unknown (see comment) Homsap IGHV3-7*01 F (see comment) 756 82.95 180/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggagtcacctttagtgactattggatgagctggatccgccaggctccagggaaggggccggagtgggtggccaacatagagcaagatgggagtgagataaattatgtggactctgtgaagggccgattcaccatctccagagacaacaccgagaatgcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18656 JY8QFUQ01B5F3C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CASDMIRGEYDAFDIW in-frame + ctctgaattcacctttaacaattctgtcatggtctgggtccgccaggctccagggaaggggctggagtgggtctcagaaattagtggtagtggtactagcacatattacgcagactccgtgaagggccggttcaccatttccagagacaattccaagaacacactttttctgcaaatgaacagcctgagagtcgacgacacggccgtatattattgtgcgagtgatatgattcggggagaatatgatgcttttgatatctggggccaagggacaacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggttaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18657 JY8QFUQ01AL9MI productive Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVRDGARRTNQWLAHDFW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagctttaatgccttctatatgggttgggtccgccaggctccaggaaaggggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18658 JY8QFUQ01DFAF1 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaAaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18659 JY8QFUQ01BEQ30 No results 18660 JY8QFUQ01DJCEH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 18661 JY8QFUQ01CAVKW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaggggcgtggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18662 JY8QFUQ01AQBZ9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18663 JY8QFUQ01APJHU productive (see comment) Homsap IGHV3-7*03 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggattcacttttagtgactattggatgagttgggtccgccaggctccagGggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18664 JY8QFUQ01AJG2F productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18665 JY8QFUQ01B1MCX unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18666 JY8QFUQ01BVL07 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 838 87.21 191/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); gcctctggattcacAttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgttccagtggtgataggacacactatgcagactccgtgaaggGgccgcttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 18667 JY8QFUQ01B94C3 No results 18668 JY8QFUQ01BO8WN productive (see comment) Homsap IGHV4-61*02 F 830 86.43 191/221 nt 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); tctctggtgcctccataaataggggtaattattactgGgaactggatccggcagcccgccgGggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18669 JY8QFUQ01DA68T productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccca 18670 JY8QFUQ01CZEBO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - gcctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18671 JY8QFUQ01CN1OP productive Homsap IGHV3-11*01 F 946 92.69 203/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD2-21*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARGKMVSTGMDVW in-frame - Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ggctctggattcacgtttagtgactactacatgacctggattcgtcaggctccagggaagggcctggagtgggttacatatattagtagtagtggtggtaacacacattacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacgcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18672 JY8QFUQ01DO5GE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 761 83.03 181/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18673 JY8QFUQ01DFY56 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18674 JY8QFUQ01B43L0 productive Homsap IGHV3-9*01 F 891 90.32 196/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - ctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18675 JY8QFUQ01CV708 productive Homsap IGHV4-61*02 F (see comment) 578 73.76 163/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERRDSIRGATGLDYW in-frame + Low V-REGION identity (73,76% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtagccccatcagcgactccaattatttctggacctgggtccggcagcccgccgggaaggaatttgagtggatcggacatgttctcaataatgcatatagcgagtataatccctccctagggagtcgcgtcaccgtgtcaatggacaagtccaagaatcagttttccctgaagttggagtctctgaccgccgcagacacggccacttatttttgtgcgagagagcgtcgggattcgattcgcggagcgacaggccttgactactggggccagggaattttggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18676 JY8QFUQ01BE1Z2 unproductive Homsap IGHV3-11*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARYRGSYYDYGGVDV## out-of-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggcttcagattccgtgactactacatgacgtgggtccgccaggctccagggaagggtcttgagtggctttcctccatcagcagcggtagtaataccatccactactcagactcggtgaggggccgcttcaccatctccagggacaacaccaggaactcagtggatctgcaaatgaatagtctgagagccgaagacacggccgtctattattgtgcgaggtacagaggcagttactacgactatggcggtgtggacgtctgggggccaagggaccgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 18677 JY8QFUQ01CA0F8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 644 77.06 168/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18678 JY8QFUQ01A6L6Y No results 18679 JY8QFUQ01A97F7 unknown (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 18680 JY8QFUQ01BG2T4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - agcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18681 JY8QFUQ01BFYLR unproductive Homsap IGHV3-7*02 F 917 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 7 8 X 7.8.X [1.16.38.11] CARDQVTEDY# out-of-frame + in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18682 JY8QFUQ01B5ZV4 productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + tctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18683 JY8QFUQ01A13UB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 845 88.37 190/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'CC' (2 nucleotides at position 27 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 93 to 94 in the user submitted sequence), (cause frameshift); ctggattcaccttcgggaacctatggCCatgacgtgggtccgcctgactcctgggaaagggctggagtggGgtttcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18684 JY8QFUQ01A4E26 No results 18685 JY8QFUQ01BSZDV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 942 92.27 203/220 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame - agcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccgagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18686 JY8QFUQ01A5V4C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttcccccgaaccggtgacggtgtgcgtggaactca 18687 JY8QFUQ01BA01C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18688 JY8QFUQ01B0A6E productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18689 JY8QFUQ01B6G3Q productive Homsap IGHV4-39*02 F (see comment) 776 83.71 185/221 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD2-15*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARHLTNSDVVHHFYSGVDVW in-frame + Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcagtaatgataattatttctgggcctgggtccgccagtccccagggaagggtctgcagtggattggcagtatgtattatagtgggggcaccttttacgacccgtccctcaagggtcgaatcaagttgtccgttgacgtgtcgaagagccacttcctcctgaacctgacctctgcgaccgccgcagacacggctgtctattactgtgcgaggcatttgaccaactcagatgtggtccatcacttctactccggagtagacgtctggggcctcgggaccacggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18690 JY8QFUQ01C4V01 No results 18691 JY8QFUQ01AO121 productive (see comment) Homsap IGHV4-61*07 F (see comment) 1023 98.58 208/211 nt 98.1 207/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [2.17.37.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01AO121 ; 10 AA in Homsap_IGHV4-61*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 75 of V-REGION: 2 nucleotides (from position 131 in the user submitted sequence), (cause frameshift) tgtctcctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18692 JY8QFUQ01BBEKI unproductive Homsap IGHV3-48*03 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ5*01 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.16.38.11] CARDKGWSGYGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 41 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagttcttatgccatgaactgggtcgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 18693 JY8QFUQ01ADMT0 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1075 100.0 216/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-2*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKPSSTSSRARTSHFDYW in-frame - tctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaagcctagtagtaccagctcccgcgctcgcacctctcactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18694 JY8QFUQ01BTW17 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18695 JY8QFUQ01B0L8O unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD1-1*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGSSKAYNWF#PW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtaattacgacatgcactgggtccgccAaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgaccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc 18696 JY8QFUQ01AOKGG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18697 JY8QFUQ01DJIVW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDLGLVGATGLDYW in-frame + ctctggattcacctttcgcagatatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattaataatagtggtggtagcacatactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcaactgagcagcctgagagccgaggacacggccatgtatttctgtgtgaaagatctgggactagtgggcgctactgggctggactactggggccagggaacccgggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18698 JY8QFUQ01AVEUZ productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDRNYAFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagcagcGtttagtatgaactgggtccgccaggctccagggaagggactggagtggctttcatacattagtaatactggtagtaacaaatactacgcagactctgtgaagggccgattcaccatctccagagacgatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgtgcgagagatcggaactacgctttcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18699 JY8QFUQ01C4CCO No results 18700 JY8QFUQ01CC96N productive Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18701 JY8QFUQ01BG9LH productive Homsap IGHV3-7*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + cctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcccatgctggtccaggggcttcttccccctag 18702 JY8QFUQ01AZ9YI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18703 JY8QFUQ01B6S4O productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggGggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18704 JY8QFUQ01C3IW2 No results 18705 JY8QFUQ01B7TT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CAKVRNSGSVWEGFSFDYW in-frame + cctctggattcatcttcagcaaccatggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcaaacattgctggaagtggtggcagtatatataacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacaccctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagtgaggaatagcggtagtgtctgggaaggattctcctttgactattggggccagggagtcctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18706 JY8QFUQ01AJVDN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18707 JY8QFUQ01BLGCA productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD4-17*01 F 3 8 7 16 8.7.16 [1.17.38.11] CARGSVTTWRRENWFDPW in-frame + tctctggtggctccatcagtacttattactggaactggatccggcagcccccagggaagggactggagtggattgggtatatccataacagtgggagtagcaactacaacccctccctcaagagtcgagtcaacatatctgtagacgcgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtttattactgtgcgagaggttcggtgactacgtggagacgggagaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18708 JY8QFUQ01DBBP4 productive Homsap IGHV3-23*05 F (see comment) 443 82.44 108/131 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (82,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18709 JY8QFUQ01CGYBO unproductive Homsap IGHV4-61*02 F 898 89.64 199/222 nt 88.74 197/222 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [2.17.38.11] CARDPQGFICSGGSCRSSAMDV## out-of-frame + in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'CA' (2 nucleotides at position 161 to 162 in the user submitted sequence), (cause frameshift); gtctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacCccctccctgcagggtcgagtcaccatgtcagtagacacgtccCAaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccaggggtttatttgtagtggtggtagctgccgctcttctgcaatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtcggaact 18710 JY8QFUQ01BMD3A productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18711 JY8QFUQ01BXXFO No results 18712 JY8QFUQ01B5TGS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18713 JY8QFUQ01BMXKS No results 18714 JY8QFUQ01CXWQ9 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 184 90.91 40/44 nt 8 X X 8.X.X [1.5.X.X] null + No rearrangement found cctggattcaccttcagcaagtatgccatgagctgggtccgcca 18715 JY8QFUQ01DA5P9 productive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [0.17.38.11] CARVIPGRGNYAFDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 201 to 201 in the user submitted sequence), (cause frameshift); ctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacgGgctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggttcagggcttcttccccca 18716 JY8QFUQ01B97QO productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaaccggtgacggtgtcgtggaaactca 18717 JY8QFUQ01CT7RH productive Homsap IGHV4-39*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.17.38.11] CARIVVRQFDQW in-frame + tctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaaggggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18718 JY8QFUQ01BO4ET productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatagtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18719 JY8QFUQ01CQK7E productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVKDMIGREDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagGggaaggggttggtgtgggtcgcacgtacgaatgaagatggaaggaccacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgttgtatttgcaaatgaacagtctgagagtcgaggacacggctctttattactgtgtaaaagatatgattgggagggaggactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18720 JY8QFUQ01CJV03 unknown (see comment) Homsap IGHV4-61*03 F, or Homsap IGHV4-61*04 F (see comment) 329 61.01 133/218 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (61,01% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18721 JY8QFUQ01AB2U7 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [2.17.38.11] CARDRGLW*WCMPCR#DYW out-of-frame - stop codons gcctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcgggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18722 JY8QFUQ01BIEGC No results 18723 JY8QFUQ01B0AEI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.37.11] CAKDASRYYYNSYCDNW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 213 in the user submitted sequence), (cause frameshift) ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 18724 JY8QFUQ01DB8ZZ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18725 JY8QFUQ01DROD3 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 761 81.94 186/227 nt 81.06 184/227 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [2.17.38.11] CSTGGPNGYHSTYPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'TG' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); aggcctctggattcgccttcaataTGcgaagtggatgagttGgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18726 JY8QFUQ01CK0OK productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 591 73.36 168/229 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 8 10 8.8.10 [5.17.38.11] CGTFGGTHFDDW in-frame - Low V-REGION identity (73,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release accggaatcagattcggaagcaaattcggcaatgcctggggtcggttgggtgcgccagaagcccgggaaaggcctggagtggatgggaatcattcatccgagtgactctgaggctagatatggtccgtccttcaaaggccaggtcaccttctcggtcgacaagtccaccgatatcgcctacttgaattgggaccgcctggcggcctcggacaccgccacatattattgtggtacctttggtgggacccactttgacgactggggccagggaactgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18727 JY8QFUQ01CA2DS No results 18728 JY8QFUQ01DKH79 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgcctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18729 JY8QFUQ01AMMGW productive (see comment) Homsap IGHV3-7*01 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [2.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttagagactattggatgagttAgggtccgccaggctccTagggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18730 JY8QFUQ01ABG07 productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 822 86.92 186/214 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD4-17*01 F 3 8 8 12 8.8.12 [0.17.38.11] CAMTRDRGYYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggaggctccttcagcatgtatgacatcagctgggtgcgacaggcccctgggcaagggcctgagtggatgggagcgatcaaccctgtctttcgtatagcgaattacgctcagaggttccagggtagagtcaccattatcgcggacgactctacgagcacagcctacatggagctggacagcctgacgtctgaggacacggccatttattactgcgcgatgacgagggaccgcggatactactttgactcctggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccaaatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18731 JY8QFUQ01AEOFO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 18732 JY8QFUQ01CDLSS productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + cctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18733 JY8QFUQ01BE2WG productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 920 92.92 197/212 nt 91.98 195/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [0.17.37.11] CAKVGNLYFFEYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 172 in the user submitted sequence), (cause frameshift) tggattcagcttcagtagctacagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatctattagcaccaccagtagtaccataggctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgttctgcaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18734 JY8QFUQ01CY3VH productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [0.17.38.11] CARLHGYCGGGYCYDWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tggatacagcttcaccgactattggatcggctgggtgcgccagatgcctgggaaaggcctggagtggatgggaatcatctatgttggtgacagtgataccaCgatacagcccgtccttcctaggccaggtcaccatttcagccgacaagtccaccaacaccgcctacctccagtggggcagcctgaaggcctcggacagcgccacatactactgtgcgagactccatgggtattgtggtggtggttattgctacgactggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18735 JY8QFUQ01CZ93G productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18736 JY8QFUQ01CNB4F No results 18737 JY8QFUQ01B2G11 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18738 JY8QFUQ01DIXIG No results 18739 JY8QFUQ01BU9SI unknown (see comment) Homsap IGHV3-7*03 F (see comment) 203 54.59 119/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (54,59% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18740 JY8QFUQ01BAYJS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18741 JY8QFUQ01A56L5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 88.94 185/208 nt 87.98 183/208 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 6 8 14 6.8.14 [X.17.38.11] CARGRATGLVDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); caccttcaccGaactacgccatgacctgggtccgccaggctccagggaaggGggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18742 JY8QFUQ01AJMD8 productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18743 JY8QFUQ01B5IJG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.71 199/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 8 15 8.8.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - ctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18744 JY8QFUQ01A89UI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaa 18745 JY8QFUQ01CRB76 productive (see comment) Homsap IGHV3-7*01 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagGggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18746 JY8QFUQ01ASKEO productive (see comment) Homsap IGHV3-48*03 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARESWWSGFYGWYNPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcataGcattagtgatagtggtagtcgcatttactatgcagactctgtgagggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacaacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18747 JY8QFUQ01AFD6W productive (see comment) Homsap IGHV3-11*01 F 811 85.84 188/219 nt 84.93 186/219 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [2.16.38.11] CADIKLGDWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 43 in the user submitted sequence), (cause frameshift) cgcctctggattcacctttagcagctatgccatgagctggatcgccaggctccaggaaaggggctggaatggaAttttatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18748 JY8QFUQ01BUG8O productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 942 92.27 203/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ggcctctggattcacctttggGttattatggcatggactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18749 JY8QFUQ01ABGL7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcgaaggactacttccccgaaccggtgacggtgtcgtggaactc 18750 JY8QFUQ01BO1DB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcCacttttgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagcggtagtgatggtagcaaatactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18751 JY8QFUQ01BKTU0 No results 18752 JY8QFUQ01BNONJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-10*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARKRVPGGDFLWGTTG in-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccgggggggactttttatgggggactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga 18753 JY8QFUQ01CIS2I No results 18754 JY8QFUQ01CDY8Q productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggGggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgCtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18755 JY8QFUQ01AOGPF productive (see comment) Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18756 JY8QFUQ01CWMJ0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca 18757 JY8QFUQ01BVSN2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattTcatcttcagtagctatgccatgagttgggtccgccaggctccagggaaggggctggaatGgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18758 JY8QFUQ01C11XL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 899 91.16 196/215 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [0.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - ctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18759 JY8QFUQ01BMJ5W No results 18760 JY8QFUQ01AHPHF unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttaatagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccgaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18761 JY8QFUQ01C6KZA unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD3-10*02 F 2 8 8 X 8.8.X [1.17.38.11] CAREFPGAFFGQ#YGMDVW out-of-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttccgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18762 JY8QFUQ01C7QY8 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt 90.58 202/223 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [1.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaaaagcacaattgatggtgggacaacatcctacgctgccCcccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 18763 JY8QFUQ01AX3XE unproductive (see comment) Homsap IGHV1-2*02 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGDDVGTIIGE##DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'AA' (2 nucleotides at position 112 to 113 in the user submitted sequence), (cause frameshift); tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacaAAaaattttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagagggggggacgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18764 JY8QFUQ01CPSVL No results 18765 JY8QFUQ01CZYOR unknown (see comment) Homsap IGHV3-33*03 F 937 92.24 202/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found gcgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggcagcagtggctggtttggacgttgtggacgtctgggggccaagggtaccgacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18766 JY8QFUQ01DLNUP productive Homsap IGHV2-26*01 F, or Homsap IGHV2-5*01 F or Homsap IGHV2-5*02 F or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*08 F or Homsap IGHV2-5*09 F or Homsap IGHV2-70*12 F 155 100.0 32/32 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 X X 9 X.X.9 [X.X.10.11] CAHGTAPFDYW in-frame - tggaccctgtggacacagccacatattactgtgcacacgggacggccccttttgactactggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18767 JY8QFUQ01DWXOZ No results 18768 JY8QFUQ01B7D3E No results 18769 JY8QFUQ01C85E7 unproductive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 923 91.74 200/218 nt 89.91 196/218 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGKAGHTHYGLDV## out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); cctctgcattcaccttcagtagttatgctatgcactGgggtccgccaggccCccaggcaaGggggctagagtGgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18770 JY8QFUQ01AOAA4 productive (see comment) Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [0.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18771 JY8QFUQ01CCE8Y productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 947 92.31 204/221 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAREVIPTATYGMDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cagcgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18772 JY8QFUQ01BCF23 productive Homsap IGHV3-30*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactggatccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18773 JY8QFUQ01BDIDH unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 311 60.09 131/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (60,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagcagtggtggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18774 JY8QFUQ01ACPP2 productive (see comment) Homsap IGHV3-66*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaCccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18775 JY8QFUQ01AQXAS productive Homsap IGHV4-61*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERSISIGGAREFDSW in-frame - Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tcactggtggccccatgggcagtagtttatacttctggaattgggtccgacagcccgccgggaagagactggagtggatcggacgtgtttatgatgatgggagtacccgctacaatccctccctcaggggtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaggttgagttttgtgaccgccgcagacacggcccgttattactgtgcgagagaacggagtatttcgattggcggagcgagagaatttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18776 JY8QFUQ01AN75J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGG# out-of-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18777 JY8QFUQ01A2YVQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKSPDSGYDSNWLDPW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaacttggcgaagttcgccatgagctgggtccgccaggctcctgggaaggggctggagtgggtctcagagatcagtggctccggtagtaaagtcggatatgcggagtccgtgaagggccgattcaccatctccaaagacaattccaagaacacattgtacttgcaaatgaccgacctgagacccggcgacacggccatttattactgtgcgaaaagtcctgatagtggctacgattctaactggctcgacccctggggcctgggaaccctggtcaccgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 18778 JY8QFUQ01DVLSR unproductive Homsap IGHV3-30*08 F, or Homsap IGHV3-30*16 F 933 91.82 202/220 nt 90.91 200/220 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGKAGHTHYGLDV## out-of-frame - in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift); agcctctgcattcaccttcagtagttatgctatgcactgggtccgccaGggccccaggcaaggggctagagtgggtggcagttatatcaaatgatggaaattataacgactatgcagactccgtgaaggGggcgattcaccatttccagagacaactccaagaacacgctatttctacaaatgaatagcctgagagttgaggacacggctgtctataactgtgcgagaggaaaggctggccatacccactacggattggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18779 JY8QFUQ01DPDLC productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDNARSYYSGVPDFW in-frame + cgtctggattcaccttcagtgaccatggcatgcactgggtccgccaggctccagggaagggtctgcagtgggtggcagttgtttggcatactggagacaataaatattatgcagagtccgtgaggggccgattcaccatctccagggacaattccaagaacacactgtatctgcaaatggacgacctgagaggcgaggacacggctatgtattattgtgcgagagataatgcccggagttattattcgggcgtgcccgacttctggggccagggaaacttggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcactctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18780 JY8QFUQ01CD8Q5 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 111 95.83 23/24 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found cctctggattcacctttagtagat 18781 JY8QFUQ01BWCNH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1058 98.62 215/218 nt 98.17 214/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*03 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'CA' (2 nucleotides at position 77 to 78 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcCAgcgtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18782 JY8QFUQ01CI9ZU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 50 of V-REGION: 'TG' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift); ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggcgTGgaggtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18783 JY8QFUQ01CFQU8 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18784 JY8QFUQ01BRDHQ productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtacctatAggcatgctctgggtccgccatgttgcaggcaaggGggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18785 JY8QFUQ01CXOCE productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcttccccgaaccggtgacggtgtccgtggaactnag 18786 JY8QFUQ01CRW90 No results 18787 JY8QFUQ01DCBBE productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatcacctttggttattgatggcatgagctgggtccgccaagctccGggggagggggctggagtgggtctctggtattGaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaaggggcccatccggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 18788 JY8QFUQ01C5NUH No results 18789 JY8QFUQ01AYZ9S productive (see comment) Homsap IGHV3-48*01 F (see comment) 749 83.96 178/212 nt 82.08 174/212 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [0.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 200 to 200 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 81 in the user submitted sequence), (do not cause frameshift) ctggattcaccttcggaacctatgGccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacgGgctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 18790 JY8QFUQ01COTG1 No results 18791 JY8QFUQ01CGZZ6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AAGT' (4 nucleotides at position 78 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'T' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAAGTgtcagtagtagtactggtTattttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18792 JY8QFUQ01CY15D unproductive Homsap IGHV3-7*01 F 931 92.59 200/216 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CATDDSNGWDEVADY## out-of-frame - tctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18793 JY8QFUQ01AB1K5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 18794 JY8QFUQ01AFPCT unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 743 82.57 180/218 nt 81.65 178/218 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARIWDSWSGA#FDVW out-of-frame - stop codons Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattCcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggGggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 18795 JY8QFUQ01BN0BZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 18796 JY8QFUQ01CYNUI productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 18 8.8.18 [2.17.38.11] CVRESGDYGGKYSKSYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagtagttatagcatgaactGgggtccgccaggctccagggaaggggctggagtgggtctcatcaattactagaagttctagttatatgtcctacgcagactcagtgaagggccgattcaccatctccagagacaatgccgagaattcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgagagaatcgggtgactacggtggtaaatatagcaagtcatactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18797 JY8QFUQ01C93RZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggGggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18798 JY8QFUQ01A5JVK productive Homsap IGHV3-48*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + cctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18799 JY8QFUQ01AAZV6 No results 18800 JY8QFUQ01DCE2O productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARPLRATYGDYVNW in-frame + cctctggattcaccttcgataactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcaaaggatggaagtattgaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacaatttatctgcaaatgaacattgtgagggttgaggacacggctatgtattactgtgcgagaccccttcgggcaacttacggtgactacgtgaactggggccagggaaccctggtcaccgtctcctcagcatccccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccggggcttcttccccca 18801 JY8QFUQ01A4H4P productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 796 99.38 161/162 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-2*01 F 2 X 7 12 X.7.12 [X.9.38.11] CARSRTFYGSANYW in-frame - gggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacgactgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggttttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18802 JY8QFUQ01CI12B productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1008 98.56 205/208 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame + caactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc 18803 JY8QFUQ01CC2MU unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [3.17.38.11] CARGAQLLCQ*WA*LL# out-of-frame - stop codons in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift); gcagcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggGCttggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagaggggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18804 JY8QFUQ01AJBHH productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18805 JY8QFUQ01CTB12 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18806 JY8QFUQ01AL7F1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 18807 JY8QFUQ01CAHX8 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CGRDERGADLPNDS## out-of-frame + stop codons Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagcttttccatggggtgggtccgccaggctccagggcggggactggagtaggtctcagccattgacggtcttactggtggtacatattacgcggactccgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggccctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18808 JY8QFUQ01BT10B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18809 JY8QFUQ01CU3GP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - cctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaatgtggtcgtcgcatgcctggtccagggcttcttccccca 18810 JY8QFUQ01C9MNR productive (see comment) Homsap IGHV4-39*02 F 1005 95.45 210/220 nt 94.55 208/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.16.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) tctctagtggActccatcagcagtactaattactactggggctgggtccgccagcccccagggaagggctggagtggattgggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 18811 JY8QFUQ01BUIMD productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame + ctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtgcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18812 JY8QFUQ01C7GNQ unproductive Homsap IGHV3-48*02 F 882 89.4 194/217 nt 88.48 192/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CASGGVTEAHY## out-of-frame + in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); ctctggattcagctccagtgaatataccatgaactgggtccgccaggctccagggaaggggctggagtgggTtttcatacattggtgttggtactggtggcatatactacgcagactctgtgaggggccgattcaccatctccagggacaatgccgagaactcagtgcatctgcaaatgaacagcctgagagacgacgacacgggtgttTtattactgcgcgagcggaggggtgacagaggctcactactggggccagggaacccctggtcaccgtctcgtcagcatcccccggaccagcccccaaagggttcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 18813 JY8QFUQ01C9D98 productive (see comment) Homsap IGHV3-11*01 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 104 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18814 JY8QFUQ01CMLGK productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 7 8 16 7.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggattcaccttcaattctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccaaagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccgagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccccca 18815 JY8QFUQ01BGBBU productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18816 JY8QFUQ01AJF1C No results 18817 JY8QFUQ01CPWIM productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggcaactcag 18818 JY8QFUQ01CVSEP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18819 JY8QFUQ01BU28D No results 18820 JY8QFUQ01A7GGK No results 18821 JY8QFUQ01BWFRJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18822 JY8QFUQ01CDQM0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 682 92.45 147/159 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-16*01 F 2 X 8 13 X.8.13 [X.7.38.11] CTRGGNYDPIPPNNW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gggctggattgggtctcacgtatcaatactgatgggagcatcagaagcttcgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgggagccgaggacacggctgtgtattattgtacaagaggggggaactatgaccccatcccgccgaacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18823 JY8QFUQ01B1E9Y productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.37.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaataacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18824 JY8QFUQ01DMNPS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18825 JY8QFUQ01C2BRO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 7 16 8.7.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ccctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcaatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 18826 JY8QFUQ01ANV52 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18827 JY8QFUQ01B978H productive (see comment) Homsap IGHV3-74*03 F (see comment) 793 84.93 186/219 nt 84.02 184/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'TC' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gcctctggattcacgttTCcacacctcctggatggcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18828 JY8QFUQ01B65L5 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 18829 JY8QFUQ01B672S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaaactc 18830 JY8QFUQ01AMFZF productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1080 97.79 221/226 nt 96.9 219/226 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'T' (1 nucleotides at position 136 to 136 in the user submitted sequence), (cause frameshift); ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtcCcccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaTgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccg 18831 JY8QFUQ01ABB70 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18832 JY8QFUQ01DC4CD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt 86.36 190/220 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CVKEDHDSGLRVLLEW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); aggctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaGgggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18833 JY8QFUQ01AC33X productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFETW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tttccggtagttccatcagtagcagtgattactactGggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattacagggggacgcagtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgaggtctgtgaccgccgcagacacggctatgtattactgtgcgagacatcggtcttttggagtgataattgtgaattactttgagacctggggacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18834 JY8QFUQ01B5F34 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARVFSGVAAPPDSW in-frame - cctctggatttcccttcaccagttactggatgcagtgggtccgccaagctccagggaaggggctggtctgggtctcacttagtaatagtgatgggagcactactacctacgcggacgccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatcttcaaatgaatcatctgagagtcgaggacaccgctgtatatttctgtgcgagagttttcagtggtgtcgctgctcccccggactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18835 JY8QFUQ01ARJHI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - gtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 18836 JY8QFUQ01ATFTP productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD4-23*01 ORF 2 10 7 17 10.7.17 [1.17.38.11] CARGECGVNCPYYNWYQHW in-frame + tgtctggtggctccatcagcagtgatgattactactggagctggatacggcagtccgccgggaagggactggagtggattgggcgaatttataaaagtggcgacacagtgtacaacccctccctcggggggcgagtcgccatgtcactggacacgtccaagaaccaattctccctgaggttgacttctgtgaccgccgaagacacggccgtctattactgtgcgaggggtgagtgcggtgtcaactgcccctactacaactggtaccaacactggggcccgggaacccgggtcaccgtcacgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccccca 18837 JY8QFUQ01AHY6K productive Homsap IGHV1-3*01 F 817 87.32 186/213 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [X.17.38.11] CVRGRSPPGDWFDPW in-frame - ggatacaccttcactaattatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18838 JY8QFUQ01DJ75W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18839 JY8QFUQ01CDJVP productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18840 JY8QFUQ01AOYJ9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18841 JY8QFUQ01C3DVY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 971 94.88 204/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 2 8 8 12 8.8.12 [0.17.38.11] CAKDQAVAGGFDYW in-frame - ctggatttacctttagctcctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtcgcaattattagtggtagtgatggtcgcacatactacgccgactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaataaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcaagcagtggctggaggatttgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18842 JY8QFUQ01AKBRD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.16.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtagctactggatcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18843 JY8QFUQ01AMFPR productive Homsap IGHV3-7*01 F 911 90.5 200/221 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [2.17.38.11] CARVIPGRGNYAFDVW in-frame - cagcctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18844 JY8QFUQ01DJI0O productive (see comment) Homsap IGHV3-30*10 F (see comment) 715 81.48 176/216 nt 80.56 174/216 nt Homsap IGHJ1*01 F 152 76.92 40/52 nt Homsap IGHD1-1*01 F 1 7 8 16 7.8.16 [1.17.37.11] CSRGTTGTTDDSRLFQHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 157 in the user submitted sequence), (cause frameshift) cctctggattcagcttcggcattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18845 JY8QFUQ01CRKLQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcagcctcacttcctatggcatgaactgg 18846 JY8QFUQ01AB3H4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 564 73.18 161/220 nt 71.82 158/220 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*01 F or Homsap IGHJ5*02 F 99 68.89 31/45 nt Homsap IGHD6-6*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKASF## out-of-frame - Low V-REGION identity (73,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); gtgtctgggggtcaccttcggtgactatgccaGtgggctggatccgccagtctcctgggggggggcCtgcagtgggtcgctgctataagtcctgacggaaaaaaCgactttctacgcagactccgtggcgggccggttccacatttatagagacaatccaataaaaactgtttttctgcaaatgaatggcctgagagtcgaagacacggccatctattactgtgcgaaggcgtccttttggggggcagggatcccaggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18847 JY8QFUQ01A0JPR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt Homsap IGHJ5*02 F (see comment) 156 78.43 40/51 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [2.17.38.11] CTRVFSGVAAP#DLW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcgcctttagaagttactggatgcactgggtccgccaagttccaggaaaggggctggtgtgggccgcactcactaatagtgatgggagtgtcacaacctacgcggattcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatttgcaaatgaatagtctgagagccgacgacacggccgtttattattgtacgagagttttcagtggtgtggcagcgccccggacctttggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18848 JY8QFUQ01DU2T0 No results 18849 JY8QFUQ01AZA1D productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 773 83.04 186/224 nt 82.59 185/224 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYHSTYPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggGggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18850 JY8QFUQ01B781B productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 948 93.93 201/214 nt 92.99 199/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-8*02 F 3 8 7 14 8.7.14 [1.16.38.11] CARGRCGLVGCWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 48 in the user submitted sequence), (cause frameshift) tctatggtgggtccttcagtggttactactggagctggatccgccagtcccagggaaggggctggagtggatcggggaaatcaatcataatggatccaccagctacaacccgtccctcaagggtcgagtcaccatatcagtagacacgtccaagaaccagttctccctaAaagctgagttctgtgaccgtcgcggacacggctgaatatttctgtgcgagaggtcgctgcgggcttgtggggtgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18851 JY8QFUQ01AY5UE No results 18852 JY8QFUQ01C73V4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 927 92.17 200/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARHNYGNEKYIMDVW in-frame + ttttggatacaactttgccacctattggatcggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatgatctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18853 JY8QFUQ01ARHTV unproductive (see comment) Homsap IGHV3-48*04 F, or Homsap IGHV3-69-1*01 P (see comment) 353 74.81 98/131 nt 74.05 97/131 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD2-15*01 F 1 X 5 12 X.5.12 [X.X.38.11] CAKGGW*RRP*LLG in-frame - stop codons Low V-REGION identity (74,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); ctctggattcaccctttagtaaccattggatgaactggggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtatTtactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18854 JY8QFUQ01CU8N8 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18855 JY8QFUQ01BRZLC productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 701 80.93 174/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 7 19 8.7.19 [1.17.38.11] CARAYTFSLFGVASHWYFDLW in-frame + Low V-REGION identity (80,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaggggctggagtggattggggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatactttttcactttttggagtggcctcacactggtacttcgatctctggggccgtggcaccctggtcacagtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18856 JY8QFUQ01BFD4A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18857 JY8QFUQ01CM4DL productive (see comment) Homsap IGHV3-30*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAGDLTGVPYYYDSSGLKYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctagattcaccttcagtagctataatatgcactgggtccgccaggctccaggcaaggGggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 18858 JY8QFUQ01CEO3U No results 18859 JY8QFUQ01AF3TS productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTRSSNSAYDYW in-frame - ctctggattcacgtttagtaacagttggatgggctgggcccgccaggctccagggaaggggctggagtgggtggccagcacaaaccaagatgcaagtgagaaaaagtatgtggactctgtgaggggccgattcaccatctcaagagacaacgccaagaactcactgtatttacaaatgaacagcctaagagccgaggacacggctttatatttctgtacgaggtccagtaacagcgcttatgactattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18860 JY8QFUQ01BBTA4 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt 85.07 188/221 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRWARQRLVMDYFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctctggtggActccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtgtacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18861 JY8QFUQ01CKTAT unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGVRGVGAYYIYYFDL## out-of-frame + ctctggattcacctttagtacctattggatgggctgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatgggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 18862 JY8QFUQ01CH5GA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18863 JY8QFUQ01BBGSE productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18864 JY8QFUQ01B27FW No results 18865 JY8QFUQ01BL28Q productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18866 JY8QFUQ01AD2PJ No results 18867 JY8QFUQ01B9FNC No results 18868 JY8QFUQ01BFJVH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.37.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 168 in the user submitted sequence), (cause frameshift) ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18869 JY8QFUQ01BG8NO productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18870 JY8QFUQ01CB08I productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18871 JY8QFUQ01CUUK1 productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 3 9 7 14 9.7.14 [1.17.38.11] CARLLAPSAVGPFDFW in-frame + tctctggtgactccatcagcggtagcaattggtggagttggatccgccagcccccagggaaggggctggagtggattggggaaatctctcatagtgggaacactaactacaacccgtccctcaagagtcgggtcaccatatcagtcgacaagtccaagagccagttctccctgaacctgagcgctgtcaccgccgcggacacggccgtatattactgtgcgagactgctcgccccatcggccgtgggaccctttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcctgcctggtccagggcttcttccccca 18872 JY8QFUQ01A46LV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGVDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatTttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtgtggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcttccccgaaccggtcgacggtgtcgtggcaactcag 18873 JY8QFUQ01B6P8J productive Homsap IGHV3-48*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + ctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18874 JY8QFUQ01B7921 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRIVSVGMAGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tctctggattcaccttcaGggaactattggatgcactgggtccgccaagctccagggaaggggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacagccgtatatttttgtgtaagaggccgtatagtgtcagttggtatggcaggctggttcgacccctggggccagggaacgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18875 JY8QFUQ01AJQB3 unproductive (see comment) Homsap IGHV3-11*01 F 904 91.2 197/216 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGPPYLYGSHGNSFDQ## out-of-frame - stop codons tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtgggtaacccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccacgggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcatagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18876 JY8QFUQ01DM42W No results 18877 JY8QFUQ01B77QK productive Homsap IGHV4-4*07 F 858 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18878 JY8QFUQ01AAXK2 unproductive Homsap IGHV3-9*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKDRKGSNWYYFG#W out-of-frame - ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttggaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18879 JY8QFUQ01BPYN9 No results 18880 JY8QFUQ01ANHVK productive Homsap IGHV4-61*02 F 965 93.21 206/221 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18881 JY8QFUQ01A6BZG unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 689 79.82 174/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (79,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18882 JY8QFUQ01B0ZXZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 989 95.81 206/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - ctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18883 JY8QFUQ01BF5MU No results 18884 JY8QFUQ01A836E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 929 91.4 202/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [3.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift) gcagcctccgaattcaTccttgagcagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18885 JY8QFUQ01BXUGL productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtagaact 18886 JY8QFUQ01CO10V unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ5*02 F 146 77.55 38/49 nt Homsap IGHD3-9*01 F 3 8 7 X 8.7.X [1.17.38.11] CGRGTG#DLW out-of-frame + stop codons in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcacggttgaggattatggcgtgagctgggttcgccaagttccagggaaggggctggagtgggtctctggtcttaatttgaatggtgccacaggttatgcaaagtccgtgacgggccggtttaccatctccagagacaacgccaagaactccctgtatttggaaatggatagtctgagagtcgaagacacggccttctattattgtgggagagggacggggtgacctctggggccggggaatcctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18887 JY8QFUQ01B89TY No results 18888 JY8QFUQ01BADXF unproductive Homsap IGHV4-4*07 F 854 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CAGRNGNL##FYMW out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) tatctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggggatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaggttgagctctgtgaccgccgcggacacggccgtatattactgtgcgggaagaaatggaaatttggcctttttatatgtggggccaagggacgactgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18889 JY8QFUQ01CWQID productive Homsap IGHV1-2*02 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDWGGTYAPLDNW in-frame - tggatacattttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaaccttgaccagtgacacgtccatcagtacagcctacatggaaatgagcgggctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgctccgcttgacaattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18890 JY8QFUQ01CHG9Q No results 18891 JY8QFUQ01BJURD productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame + tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18892 JY8QFUQ01CHYC3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgGttaatggtgatCgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctttatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18893 JY8QFUQ01CA5NT productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) tctctggattcacctttagtaggtttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18894 JY8QFUQ01BOIKV No results 18895 JY8QFUQ01CMFZX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18896 JY8QFUQ01BAV1L unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 18897 JY8QFUQ01A8YFM No results 18898 JY8QFUQ01BV3BU No results 18899 JY8QFUQ01BB36Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18900 JY8QFUQ01BQW5X unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18901 JY8QFUQ01CEG44 No results 18902 JY8QFUQ01CA7NB productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt 81.4 175/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 3 8 6 15 8.6.15 [2.17.38.11] CARDWGGSFDRYYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) gtccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggctgggAgacatcaactttaaaggaagcacaattacaacccgtccctcaagagtcgactcaccatattagcagacttgtccaggaatcgcttctctctagaactaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtgggagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18903 JY8QFUQ01B6AAU productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 819 86.64 188/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-17*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARHSGALATGSQNWFDPW in-frame + gtcgggatttaggtttgatgattttggcatgagctgggtccgccaagttccagggaagggcctggaatgggtctctggtagtgactggagtggtggaagaacaggttatggtgactctgtgaagggacgattcatcatctccagagacaacgccaagaactccctatatctacaaatgaacgatctgcgagccgatgacacggccgtctattattgtgcgcgacatagtggggcgctggctactgggtctcagaactggttcgacccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18904 JY8QFUQ01DPKTF unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 971 94.42 203/215 nt 93.49 201/215 nt Homsap IGHJ6*04 F (see comment) 99 61.9 39/63 nt Homsap IGHD6-6*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARAPRGEYSNSSV*LLG in-frame - stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'TGG' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); tctatggtgggtccttcactgactcctattggagctggatccgccagcccccagggaaggGggctggagtgcattTGGgggaaaatcaatcatagtggaagaaccaactacaacccgtctctcaagagtcgagtcaccatatcagtagacccgtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggctgtgtattactgcgcgagagccccaaggggggagtacagcaactcgtccgtttgactactgggggccaggggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 18905 JY8QFUQ01B9IMG productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'CG' (2 nucleotides at position 194 to 195 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccCGggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18906 JY8QFUQ01CF3LD unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18907 JY8QFUQ01BC3PM productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 2 10 7 19 10.7.19 [1.17.38.11] CARVVRCTTTGCSRVGWFDPW in-frame + tctctggtggctccatcagcagtgatgattactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctcttccagtgggaacaccaactacaacccctccctcaggagtcgagtcaacatttcactagacacgtccaagacccagttctccctggagctgacctctgtgagcgccgcagacacggccgtgtattactgtgcgagggtcgttcgttgtactacgaccggctgctcaagggtaggatggttcgacccctggggccagggaaccctggtaaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 18908 JY8QFUQ01CEXJ3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*01 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGVGAYYIYYFDLW in-frame + ctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatggggccaaggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18909 JY8QFUQ01B81TC productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 976 92.89 209/225 nt 92.44 208/225 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*02 F 1 10 9 16 10.9.16 [1.17.37.11] CAKDPQQLLEDINWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 89 of V-REGION: 1 nucleotides (from position 179 in the user submitted sequence), (cause frameshift) ctccggggacagtgtctctagcaacagtgccacttggaactggatcaggcagtccccaacgggaggccttgagtggctgggaaggacatcctacaggtccaaatggtatagtgattatgcggtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctcctgcaattgaactccgttagtcccgaggacacggccgtctattactgtgcgaaagatcctcagcagttattggaagacataaactggttcgacccctggggccagggcacccaggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18910 JY8QFUQ01B3FJT productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18911 JY8QFUQ01A6E8N productive Homsap IGHV1-2*04 F 885 90.65 194/214 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [0.17.38.11] CARERIFGADYYYYHGMDVW in-frame + tggatacagcttcaccgactactatatacactgggtgcgacaggcccctggacaggggcctgagtggatggggtgtatcaaccctaatactggtgacacaagatattcacggaagtttcaggcctgggtcaccatgaccagggacacgtccatccgcacggcctacatggagctgagcagcctgaaatctgacgacacggccgtgtattcctgtgcgagggagcggatttttggagccgattactactactaccacggaatggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 18912 JY8QFUQ01DQC2Y productive Homsap IGHV3-30*07 F 842 87.61 191/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CASLGSYESSGPRW in-frame + cctctggattcctcttcagtagttatgctatacactgggtccgccaggctccaggcaaggggcttgagtgggtggcggttgtttcatatgatggaaataataaattttacgcagactctgtgaagggtcgattcagcctctccagagacaactccaagagcacggttgatctgcaaatggacaacttgagatccgaagacacggctgtatattattgtgcgagcctcggttcctatgagagcagtggtccccgatggggcccgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18913 JY8QFUQ01CV3LG unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18914 JY8QFUQ01C9Y1A No results 18915 JY8QFUQ01AJQ34 unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD1-1*01 F 1 8 7 X 8.7.X [1.17.38.11] CARGSSKAYNWFD#PG out-of-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18916 JY8QFUQ01CX1MR productive Homsap IGHV3-7*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + cctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccgggtgacggtgtcgtggaacctcag 18917 JY8QFUQ01BKIC6 productive (see comment) Homsap IGHV3-30*01 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [2.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gcctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18918 JY8QFUQ01C4EP3 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 18919 JY8QFUQ01B2HTR productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18920 JY8QFUQ01BZ690 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18921 JY8QFUQ01B7WTW productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18922 JY8QFUQ01BDNIC productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 88.99 194/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD2-2*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARYCSSDSCQGYHDAFDVW in-frame - cttctggatacatcttcacgaaccactggatcggctgggtgcgccagatgccgggtagaggcctggagtggatggggatcatctatcctggtgactccgattccagatacggcccgtccgcccaaggccaggtcaccttctcagtcgacaagtccatcgccaccgcctaccttcagtggagtagcctgaaggcctcggataccgccacgtactactgcgcgagatattgtagtagtgacagctgccaagggtaccatgatgcttttgatgtctggggccaagggacaatggtctccgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18923 JY8QFUQ01CXS7N productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18924 JY8QFUQ01CX9NA unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*05 F 948 91.93 205/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 10 X 8.10.X [1.17.38.11] CVVDIPEVVWG#FDYW out-of-frame + ctctggattctctttcacttatgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttgcccttattaaaagcaaaactagtggtgggacaacacactacgctgcacccgtgaaaggcagattcaccatctcaagagatgattcagagaacacgttctatctacaaatgaatagactgaaaaccgaggacacagccgtgtattattgtgtcgtagatataccagaagttgtgtgggggaatttgactactggggccagggagccctggtttccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18925 JY8QFUQ01BN711 productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'C' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtCgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18926 JY8QFUQ01ASSCV productive Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18927 JY8QFUQ01CT3GZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [2.17.38.11] CARDSALFGYARYDAMDAW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) gcctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 18928 JY8QFUQ01C8PAO unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18929 JY8QFUQ01DCRUB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 937 92.24 202/219 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDQSLGMPEAFDIW in-frame - gcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18930 JY8QFUQ01BB35T productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 875 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcganaggcCccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccGggggcanagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18931 JY8QFUQ01AOWMN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1077 99.09 218/220 nt 97.27 214/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 45 to 46 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 62 in the user submitted sequence), (cause frameshift) cagcctctggattcaccGttcagtagGctatagcatgaactgggGTccggccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18932 JY8QFUQ01AENJP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18933 JY8QFUQ01BDHSG productive (see comment) Homsap IGHV1-18*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacacctttaccagatatggtattagttgggtgcgacaggCcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18934 JY8QFUQ01CU0DA unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F (see comment) 541 71.69 157/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found Low V-REGION identity (71,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18935 JY8QFUQ01BBID5 productive Homsap IGHV4-34*10 F 818 86.98 187/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccaagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18936 JY8QFUQ01B7Q12 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 94.42 203/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [0.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18937 JY8QFUQ01CHBIN unproductive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFLDY## out-of-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18938 JY8QFUQ01BK2WO No results 18939 JY8QFUQ01C8CBF No results 18940 JY8QFUQ01CZDFF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 815 86.24 188/218 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARILTLFAVVTSSGMDVW in-frame - Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) ctctgggatttaccttcagtaattatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggccgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18941 JY8QFUQ01CQ5SW productive Homsap IGHV3-66*02 F 813 86.92 186/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-10*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARVRFGPSYLDVFDIW in-frame + ctctggattcaccgtcaatagttatcacatgagttgggttcgccaggctccagggaaggggccggagtgggtctcaattatttatccggatggtgacgcattctacgcagactccgtgaagggccgattcaccttctccagagacatttccaagaacacggtgtatctccaaattaacagagtgacaactgaggacacggctatgtactactgtgcgagagtccggttcgggccaagttatctggatgtctttgacatctggggccaagggacattggccaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18942 JY8QFUQ01CJ40J productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 7 13 8.7.13 [1.17.38.11] CTRGRSDAWELSDHW in-frame + tcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 18943 JY8QFUQ01A2FPR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 895 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD5-18*01 F 1 7 8 X 7.8.X [1.17.38.11] CANELGYCSGR## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) cctctggattcaccttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggantgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaAagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtcggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18944 JY8QFUQ01DF8SK No results 18945 JY8QFUQ01CJ3EX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1000 95.43 209/219 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [2.17.38.11] CARLCGNDCRNDVFDIW in-frame - gcctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18946 JY8QFUQ01B0WOE unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 985 95.37 206/216 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found tctggattcaccttcaataactataacatgaactgggtccgccaggctccagggaaggggctggagtggatctcatccattagtagtggtagtaatgacataaactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggtcggtgccgcaaccaaagtactacggtatggacgtctgggggccaagggaccacggtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18947 JY8QFUQ01C1I0C No results 18948 JY8QFUQ01DLYDH productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18949 JY8QFUQ01BUW1C No results 18950 JY8QFUQ01BTZ0V productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaaccccttcctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18951 JY8QFUQ01B90VX No results 18952 JY8QFUQ01C310D productive Homsap IGHV4-61*06 ORF, or Homsap IGHV4-61*07 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 10 7 17 10.7.17 [2.17.38.11] CAGEQMIDAVSHNYAMDVW in-frame - gtctcctggtggctccatcagcatcaatacttacttctggagttggatccggcagcccccagggaagggactggagtggattgggtatatctctcacagtgggagtgccaactacaacccctccctcgagagtcgagtcaccatcttaagagacacgtccaagaaccagttctctctgaggctgagggctgtaaccgcggcggacacggccgtgtatttctgtgcgggggaacagatgattgacgcagtctcccacaactatgccatggacgtctggggccaagggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 18953 JY8QFUQ01DJHRX unknown (see comment) Homsap IGHV3-74*03 F 94 52.24 70/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18954 JY8QFUQ01B25XE productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18955 JY8QFUQ01A05F1 unproductive Homsap IGHV3-7*01 F 879 91.0 192/211 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-16*01 F 2 7 8 X 7.8.X [X.17.38.11] CAKRFLR#AFDLW out-of-frame - attcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagccgaggacacggctgtctattattgtgcgaaaagatttttacgtacgcctttgatctctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18956 JY8QFUQ01A7RE2 No results 18957 JY8QFUQ01A5I8W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18958 JY8QFUQ01CQSIX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggGggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccagttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18959 JY8QFUQ01A9NYV productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 752 90.66 165/182 nt 90.11 164/182 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.5.38.11] CARESGAGISAVEFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 35 nucleotides (from position 42 in the user submitted sequence), (cause frameshift) ctctggattcacctttgataattattggatgagctgggtccaccattaggcgcgatggaggtcagaaatactatgtggactctgtgaagggccgattcatcatctccagagacaacgccaagaagtcactgtttctgcaattgaacagcctgacagccgaggacacggctgtatattactgtgcgagagagtctggggccggaatttctgcggtggagtttgactattggggccagggaactgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccgaaccggtgacggtgtcgtg 18960 JY8QFUQ01BGDRW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.5 200/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKDQSCIVGPCGFDYW in-frame - cagcctccgaattatccttnagcagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18961 JY8QFUQ01DO320 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [2.16.38.11] CAKDIWAREWNDMAAFQMW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) cgcccccggaatcacttttcccagctatgtcatgagttgggtccgccaggcccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18962 JY8QFUQ01BFZOR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcacttttaggagtcatatgatgagttgGggtccgccagactccagggaaggGggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtatttgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18963 JY8QFUQ01BO3A8 No results 18964 JY8QFUQ01B98OJ No results 18965 JY8QFUQ01A4ZZR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18966 JY8QFUQ01CZMSS productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 169 82.0 41/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDSG in-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgattctgggggcccagggacagtggtcatcgtctcttcatcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18967 JY8QFUQ01CZUEE productive (see comment) Homsap IGHV3-7*01 F 950 93.12 203/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 21 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGAattcattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18968 JY8QFUQ01BHP64 No results 18969 JY8QFUQ01CCJWA unproductive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGQKVATSAS#WFDSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaagtggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 18970 JY8QFUQ01CNIPU No results 18971 JY8QFUQ01BDSWW No results 18972 JY8QFUQ01AELLN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 960 93.18 205/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKGIVGDTFFDYW in-frame - agcctctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgagatcccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18973 JY8QFUQ01CCC3L unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDLFQVSTTYFDY# out-of-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18974 JY8QFUQ01BPKG7 productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18975 JY8QFUQ01CSVD2 unproductive Homsap IGHV4-61*02 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [1.17.38.11] CARDFWRFLQFSGLL# out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgGggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagatttttggaggttcctacaatttagtggcctactggggccagggaatccctggtcaccgtctcctcagcctccaccaagggccctatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 18976 JY8QFUQ01CX6D7 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccatctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttgccccgaaccggtgacggtgtcgtggaactc 18977 JY8QFUQ01AF1K4 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 900 90.78 197/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - gtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18978 JY8QFUQ01BFTCW unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 299 65.61 103/157 nt 8 8 X 8.8.X [1.17.17.X] null - No rearrangement found Low V-REGION identity (65,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatatgaacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18979 JY8QFUQ01BNVDS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 82 51.09 70/137 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccga 18980 JY8QFUQ01AQKIG productive (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcgtctttactaatcattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggGggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18981 JY8QFUQ01AVVU5 No results 18982 JY8QFUQ01BMH9V No results 18983 JY8QFUQ01BGQ8J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 811 85.84 188/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNEFGYCSGG# out-of-frame - ggctctggattcatgttcggtagttatagtctgaattgggtccgccaggctccagggaaggggctggaatgggtcgcaagtattcgtgccagtggtggtaggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgttgtatttgcaaatgtacagtctgagagtcgaggacacggccttatattattgtatgaacgaattcggatactgtagtggtgggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18984 JY8QFUQ01CB7YY unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null - No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18985 JY8QFUQ01CADY5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 729 81.57 177/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18986 JY8QFUQ01BY7RG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); ctctggatTtcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18987 JY8QFUQ01DIYNE productive Homsap IGHV3-7*03 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18988 JY8QFUQ01C8C14 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag 18989 JY8QFUQ01C0CS5 productive (see comment) Homsap IGHV4-4*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDSTGSLEDGLDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggctCccctcagtacttactactggaactgggtccggcagcccgccgggaagggactggagtggattgggcgtaaatatcccagtggggacaccaactataatccctccctcaaaagtcgagtcaccatgtcactagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagggaaggattactatgatagtactggttccctcgaggatggtcttgatatctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18990 JY8QFUQ01C3J26 No results 18991 JY8QFUQ01A29EP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcGtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 18992 JY8QFUQ01BJXZ2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 18993 JY8QFUQ01CPI0G productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcCccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 18994 JY8QFUQ01C1TBJ productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame - tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18995 JY8QFUQ01BN9JD unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CTREVGATDY## out-of-frame - tctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 18996 JY8QFUQ01C4ZLK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARDRSGQAVGYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 18997 JY8QFUQ01CQJZW No results 18998 JY8QFUQ01BBF82 productive (see comment) Homsap IGHV3-7*01 F 830 87.38 187/214 nt 85.98 184/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 7 8 12 7.8.12 [0.17.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) ctggattcagttttagtgacttttgatgcactgggtccgccaggcnccagggaaTGggggctggagtgggtggGcccacntgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 18999 JY8QFUQ01CV195 unproductive Homsap IGHV3-7*01 F (see comment) 742 82.87 179/216 nt 82.41 178/216 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.37.11] CARLKGLTHR##FYFDLW out-of-frame + Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttgggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcgacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19000 JY8QFUQ01DWZBA productive (see comment) Homsap IGHV3-11*01 F 973 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [2.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); agcctctggcttcaAccttcagtgactactacatgaactgggtccgccaggctccagGggaaggggctggantgggtttcatacattagtggaagtggaactaccatatcctacggagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19001 JY8QFUQ01CAVGN No results 19002 JY8QFUQ01CVQ6B productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 770 82.38 187/227 nt 81.94 186/227 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [2.17.38.11] CSTGGPNGYHSTYPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'AA' (2 nucleotides at position 28 to 29 in the user submitted sequence), (cause frameshift); aggcctctggattcgccttcaatatcgAAgtgggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19003 JY8QFUQ01DKKJ0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKVWIELWSAGDHFDNW in-frame + cctctggattcatatttactagatatgccatgacctgggtccgccaggctccagggaagggtctggagtgggtcgcttctatcagtggtagtgggattagtaaaaagtacgcagacggcgtggagggccgattcaccatctccagagacagttccgagagaacactgtatctacaaatgaacagcctgagagtcgaggacacggccacatattattgtgcgaaagtatggatagagttatggtcggctggggaccactttgacaactggggccagggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19004 JY8QFUQ01CIVNC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19005 JY8QFUQ01BGEYK productive (see comment) Homsap IGHV3-11*01 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 97 to 99 in the user submitted sequence), (do not cause frameshift); gcttctgggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19006 JY8QFUQ01BSNEY No results 19007 JY8QFUQ01AFUVE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19008 JY8QFUQ01CNC53 unproductive Homsap IGHV3-7*01 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGFYSTGY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19009 JY8QFUQ01BPY0E No results 19010 JY8QFUQ01DH30S productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 977 94.5 206/218 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD3-22*01 F 3 9 7 11 9.7.11 [1.17.38.11] CAGLLTTFGLQSW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcagtagtaactggtggacttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatggtggaaacacctactacaacccgtccctcaagagtcgagtcaccatatcactagacaagtccaagaaccaattctctctgaacctgaactctgtgaccgccgcggacacggccatatattactgtgcgggacttcttacgacttttggactgcagagctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19011 JY8QFUQ01BJS80 No results 19012 JY8QFUQ01C3CHE productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19013 JY8QFUQ01DE6QR unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 955 93.15 204/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CVRGGLRWRPRTLLRP#YGLDVW out-of-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagagggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19014 JY8QFUQ01BRFU0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattctccttcgaggggtctgtcgtgacctgggtccgacaggctccagggaaggggctggagtgggtctcaggtatctacggtggtgatggtacatcattttacgcagacttcgcgaagggccgattcaccgtctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19015 JY8QFUQ01CTEYF productive (see comment) Homsap IGHV3-9*01 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 17 8.8.17 [1.17.38.11] CVKDRKAGGYNLLDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaGggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19016 JY8QFUQ01C5MCI productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - ctctggatcacctttggttattgatggcatgagctgggtccgccaagctccggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19017 JY8QFUQ01COMEW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19018 JY8QFUQ01BRKER unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 19019 JY8QFUQ01CN3XN No results 19020 JY8QFUQ01AJWTG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.37.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 176 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19021 JY8QFUQ01CH10S No results 19022 JY8QFUQ01DC0U0 productive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19023 JY8QFUQ01A5AQS unproductive Homsap IGHV3-30*10 F (see comment) 708 80.45 177/220 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [2.17.38.11] CSRGTTGTTDDSRLFQH## out-of-frame - Low V-REGION identity (80,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgcctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgaaaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactgggggccagggcgccctggtcaccgtttcgtcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19024 JY8QFUQ01BPCP0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [2.16.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'GG' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) cagcctctggattcacctttaggagctatgccagagctgggtccgccaggctccagggaaggggctgagtgggtctcaactattagtggtGGaatgttgatagcacagactacgcagattccgtgaagggccggttcaccatctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19025 JY8QFUQ01CEPJM No results 19026 JY8QFUQ01CQD5V No results 19027 JY8QFUQ01BIRKM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19028 JY8QFUQ01A10TS No results 19029 JY8QFUQ01C930D productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 841 87.96 190/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [2.17.38.11] CAREFRAPSLARYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 59 to 61 in the user submitted sequence), (do not cause frameshift); gcctctggattcaccttcagcaaccataacatgacctGgggtccgccaggttcccaggGAAagggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19030 JY8QFUQ01CC0K4 productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19031 JY8QFUQ01AWYMJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + tctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19032 JY8QFUQ01AJVOK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFEYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagcagctatggcatgcactggttccgccaggctccaggcaaggggctggagtgggtggcagctatctcatatgatggaattgacaaatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaaaGcacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgcccctggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 19033 JY8QFUQ01BAFCP unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 92.86 208/224 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD2-2*01 F 1 8 7 X 8.7.X [4.17.38.11] CARGAPVFM#*C out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); cctctgcagcctctggattcattgtcaatagcaactacatgagttGgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccagttttcatgatagtgttaaaggggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19034 JY8QFUQ01A51OR unproductive Homsap IGHV4-4*07 F 850 88.43 191/216 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [2.17.38.11] CAGRNGNLA#FYIW out-of-frame - gtatctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggggatacgaactacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaggttgagttctgtgaccgccgcggacacggccgtatattactgtgcgggaagaaatggaaatttggcccttttatatctggggccaagggacgactgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19035 JY8QFUQ01C28WK productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccggaagtagttattattggggctggattcgccagTcccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19036 JY8QFUQ01A9O5T productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARGVGQQLPPLDW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctcgtggctccatcactccttcctactgGgagctggatccggcagAcccccagggaagggactggagtggattggatatatctatgacagtgggagtaccaagtacaacccctccctcaagagccgagtctccatatcaatagactcgtccaagaaccagttctccctggagctgttctctgtgaccgctgcggacacggccatatattactgtgcgagaggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19037 JY8QFUQ01APLRK productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 859 88.89 192/216 nt 88.43 191/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19038 JY8QFUQ01C2V90 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 106 55.77 58/104 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons ctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19039 JY8QFUQ01CCCYD productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame - tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19040 JY8QFUQ01AEF6H unproductive (see comment) Homsap IGHV3-48*02 F 597 94.74 126/133 nt 93.98 125/133 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD3-3*01 F 2 8 X X 8.X.X [1.11.24.11] CARARRTISGVGFY*ALRYGRL# out-of-frame - stop codons in FR2-IMGT, from codon 50 of V-REGION: 84 nucleotides (from position 62 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcaggacccatagcatgaactgggtccgccaggctccagggaagggagacaatgccaagaactcactttatctgcaaatgaacagcctgagagacgaggatgcggctgtgtattactgtgcgagagcccgtaggacgatttctggagtgggtttttattgagcactacggtatggacgtctgggggcccagggaccacggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19041 JY8QFUQ01BMLX4 productive Homsap IGHV4-61*02 F 870 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ttccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccttgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19042 JY8QFUQ01BFQYX productive Homsap IGHV2-5*02 F (see comment) 858 84.23 203/241 nt Homsap IGHJ4*01 F 195 89.58 43/48 nt Homsap IGHD1-1*01 F 2 10 7 11 10.7.11 [8.17.38.11] CARIGRLEHFDSW in-frame - Low V-REGION identity (84,23% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcacgctgacctgtaccgtctctggcttctcgctctccactcctggcgtgggcgtggcctggctccgtcagtccccaggagaggccctggagtggcttgcactcatttactgggatgatgatagccgctatagcccatctctgaaggacagactcaccatcaccaaggacacctccgaaaaccttgtggtcctgacactcagcgacatcgatacagtggacatcgccacatatttttgtgcacgcataggccgtctggaacactttgactcctggggccaaggaatactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19043 JY8QFUQ01DAFAO productive (see comment) Homsap IGHV3-48*01 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagatatagtatgaactgggtccgccaggctccaggaaaggGggctggagtgggttgcatacattagaagtagcagtagtgtcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19044 JY8QFUQ01DV5MY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 838 87.21 191/219 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARLRSFGDYPLDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19045 JY8QFUQ01CZTNE unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 19046 JY8QFUQ01CMXNJ productive (see comment) Homsap IGHV4-61*02 F 875 88.69 196/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSRTMGGARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggccCccatcagcagcagcacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccaactacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgcctctgacacggccgtatattactgtgcgagagaacatagcaggacgatgggcggggcgagagagctagactcctggggcccgggcactctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttcttccc 19047 JY8QFUQ01AZUQ0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19048 JY8QFUQ01CQW74 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcaataactataacatgaactgggtccgccaggctccagggaaggggctggagtggatctcatccattagtagtggtagtaatgacataaactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggtcggtgccgcaaccaaagtactacggtatggacgtctggggccaaagggaccacggtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 19049 JY8QFUQ01B5056 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19050 JY8QFUQ01BX3O1 No results 19051 JY8QFUQ01AD7SL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 91 71.05 27/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcatgtttagtagctttccccatggcctgg 19052 JY8QFUQ01B2RIE productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 973 92.11 210/228 nt 91.67 209/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [2.17.38.11] CARGGNYYDSGGLDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); tctccgggggacagtgtctctagcagcagtgttgTtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19053 JY8QFUQ01CQHDY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 91.78 201/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - gcctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19054 JY8QFUQ01B7VPL unproductive (see comment) Homsap IGHV3-7*01 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [0.17.38.11] CVRG*RWCQFWRN#DYW out-of-frame - stop codons in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctgggttcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgagggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19055 JY8QFUQ01A5WKX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19056 JY8QFUQ01BV0L0 productive (see comment) Homsap IGHV3-7*01 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDSPSAYDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19057 JY8QFUQ01CAT22 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19058 JY8QFUQ01BCOUS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - cctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggtcagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19059 JY8QFUQ01COKJG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacagcaaaaactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19060 JY8QFUQ01B5GFJ productive (see comment) Homsap IGHV3-7*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGSYYYYDTNGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tggatttacctttacaaattattggatgagctgggtccgccaggctccagggaGgggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19061 JY8QFUQ01B5GW8 No results 19062 JY8QFUQ01BXJNH unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*03 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 922 92.13 199/216 nt 91.2 197/216 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDEIPWDTIEYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 2 nucleotides (from position 97 in the user submitted sequence), (cause frameshift) cctctggattcaccttcactacatattccatgcactgggtccgccaggctccaggcaaGggggctagaatgggtggcagttatatcatatgatggaaaaaaaatcttatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtacctgcaaatggacagcctgaggcctgaagacacggctgtgtattactgtgccagagatgagatcccttgggatacaatagagtactactttgactactgggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagactctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19063 JY8QFUQ01DA8OU productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.37.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 161 in the user submitted sequence), (cause frameshift) ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctagcattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19064 JY8QFUQ01A5D26 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 1 8 8 18 8.8.18 [1.17.38.11] CARGEFLL*N*WSKGVFDYW in-frame + stop codons cctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaatttttactatgaaactagtggtcgaagggggtttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19065 JY8QFUQ01CW3TA productive (see comment) Homsap IGHV3-33*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) gcgtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19066 JY8QFUQ01CI8VS No results 19067 JY8QFUQ01B9ESA No results 19068 JY8QFUQ01AH5X7 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19069 JY8QFUQ01BA7Y6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtcgacggtgtcgtggcaactca 19070 JY8QFUQ01CE7ZB No results 19071 JY8QFUQ01CYCGV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggGggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19072 JY8QFUQ01ALYZC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 751 83.33 180/216 nt 82.87 179/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 19 8.8.19 [1.17.37.11] CTRGSSRGGRYDENYYELDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 82 of V-REGION: 2 nucleotides (from position 151 in the user submitted sequence), (cause frameshift) cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagttttagtcagaacatatactacagagactcagtgaggggccgattcaccatccccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19073 JY8QFUQ01B1S8U No results 19074 JY8QFUQ01AVAD8 productive (see comment) Homsap IGHV4-39*02 F 803 85.07 188/221 nt 84.62 187/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-2*01 F 3 10 7 15 10.7.15 [1.17.38.11] CASVGGRDTSGNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'CT' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagtcatagtgcttactactgggcctggatccgccagcccccagggaaggggctggagCTgggattgggaatatcaataacaatggaaaaactcactacaatccgtccctcaagagtcgagtctccatgtccctggacatgtccacggaatccttctccctggagctgacctctgtgaccgccgaagacacggcagtgtattactgtgcgagtgtagggggacgagatacaagtggcaattggttcgacccctggggccaaggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19075 JY8QFUQ01BT7QY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 769 84.26 182/216 nt 83.8 181/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.37.11] CARDSALFGYARYDAMDAW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 123 in the user submitted sequence), (cause frameshift) ctctggatccagtttcagtggttttggcgtgaactgggtccgccaggctccagggaaggggctggaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgagggccggttcaccatttccagagacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19076 JY8QFUQ01B6OHM unknown (see comment) Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.21 206/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 36 of V-REGION: 'CT' (2 nucleotides at position 28 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 113 to 124 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagcagagataCTtttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19077 JY8QFUQ01CEX28 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 941 92.66 202/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - ctctgggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19078 JY8QFUQ01DFSD4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19079 JY8QFUQ01BYLWM productive Homsap IGHV3-23*03 F (see comment) 522 71.43 155/217 nt Homsap IGHJ2*01 F 166 79.25 42/53 nt Homsap IGHD3-3*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARVRNSNWYFDHW in-frame + Low V-REGION identity (71,43% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgaagacatgtttaagagtttcggattgacgtgggtccgtcaggctccagggaaggggctggagtgggtcgcaggaataaacaattacaatggtgcaactttctatgctggccccgtaaagggccgcttcaccgtctctcgagataaagaaaagaccattttttatctacaaatggacaacgtgagggtcgacgacacgggcgtttatttctgtgcgagagtcaggaatagtaattggtacttcgaccactggggccgcggcgcactagtcacagtctccgcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttccccca 19080 JY8QFUQ01B2K9Y productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 863 89.3 192/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19081 JY8QFUQ01BCLGV No results 19082 JY8QFUQ01B3TEJ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 989 93.75 210/224 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 2 8 10 16 8.10.16 [1.17.38.11] CAADGCPGGTCYHGFDMW in-frame + cctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatggttttgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19083 JY8QFUQ01BT7VZ unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPH#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19084 JY8QFUQ01CPYLJ productive (see comment) Homsap IGHV3-7*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); tctctggattcaccGtttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19085 JY8QFUQ01CKAP3 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 824 86.7 189/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + stop codons cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgagtctcattcgttaatagtggaagtagttacatctactacgcagactcagtaaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19086 JY8QFUQ01AVX7B productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'ACAGTG' (6 nucleotides at position 19 to 24 in the user submitted sequence), (do not cause frameshift); tctctggtggctccatcaACAGTGgtagttatcactgggcctggatccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19087 JY8QFUQ01BFHKO productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19088 JY8QFUQ01DJL6V productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD5-24*01 ORF 3 10 7 14 10.7.14 [1.17.38.11] CARRGDADNYWYFDLW in-frame - tctctagtgactccatcagcagtactaattactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatgtatcatggtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacacgtccaagacccatttctccctgaagctgacctctatgaccgccgcagacacggctgtgtattactgtgcgagacggggagatgcggataactactggtacttcgatctctggggccgtggcaccctggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19089 JY8QFUQ01ASM74 unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19090 JY8QFUQ01BTZDX unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGEFLL*N*WSKG#FDYW out-of-frame + stop codons ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaatttttactatgaaactagtggtcgaaggggtttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccag 19091 JY8QFUQ01AS9TS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt 86.64 188/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 1 8 8 16 8.8.16 [1.17.38.11] CTKDPQQLLEGVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggattcacctttaggagctatgccatgagttgggtccgccaggGctccagggaaggggctagagtgggtctcgtctatcagtggcagtggtgataagacaaagtatgcagattcagtgaggggccggttcaccatctccagagacaattacgacaacacattatatctgcgaatggagggcctgagagccgaggacacggccacatattactgtacgaaagatcctcagcaactgttggaaggggtaaattggttcgacccctggggccagggaaccctggtcaaggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19092 JY8QFUQ01AR5WV productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19093 JY8QFUQ01CU9PB unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 902 90.05 199/221 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found cagcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19094 JY8QFUQ01AWJP4 No results 19095 JY8QFUQ01CG8C8 unproductive Homsap IGHV3-7*01 F (see comment) 698 80.28 175/218 nt 79.36 173/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARLKGLTHHDFYFDL## out-of-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgGggtccgccaggccacagggaaggggccggagtgggtggccaacatatcccccagacggaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19096 JY8QFUQ01BOYQG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19097 JY8QFUQ01CLTMY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame + ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19098 JY8QFUQ01AH0R7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19099 JY8QFUQ01BVK09 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19100 JY8QFUQ01BK1SN unproductive Homsap IGHV4-4*07 F, or Homsap IGHV4-59*10 F 800 86.05 185/215 nt 83.72 180/215 nt Homsap IGHJ5*02 F (see comment) 75 60.78 31/51 nt Homsap IGHD3-3*01 F 3 8 7 X 8.7.X [1.17.38.11] CARCPNYNIGTRGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'GAGTCC' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tttctggtgtctccatgagcaatGAGTCCtattactggacgtggatccgGgcagcccCGtcggggaaggggAccggagtggattgggcgcatctacaccagtgGggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19101 JY8QFUQ01B8SCQ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 737 82.79 178/215 nt 82.33 177/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtcaatcaaTagagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19102 JY8QFUQ01BMDEC unproductive Homsap IGHV3-7*01 F 990 95.39 207/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 1 7 8 X 7.8.X [1.17.38.11] CARSGSGSHLDY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) tctctggattcaccGtttagtaggtttggatgacctgggtccgccagggtccagggaaGggggctggagtgggtggccaacataaAagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19103 JY8QFUQ01A181R productive (see comment) Homsap IGHV1-18*01 F 867 89.72 192/214 nt 88.32 189/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'GGC' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tggttacacctttaccTacctatgGGCgtcaccctggggtgcgacaggCcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19104 JY8QFUQ01AYFYW productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19105 JY8QFUQ01CA7PU productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [0.17.38.11] CATSDVGARKFDYW in-frame + tggttacacctttaccagatatggtattagttgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcagcgtttccaatggtgacacaaactatgcacagaagctccagggcagagtcaccatgaccgcagacccatccacgagcacagcctacttggaactgaggagcctgacatctgacgacacggccgtatattactgtgcgacatctgacgttggagctcgaaagtttgactactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 19106 JY8QFUQ01AH5A1 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 969 93.64 206/220 nt 92.73 204/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARHGSGWLQELDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtggctGccatcatcagagacagtgcctactggggctggatccgccagccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19107 JY8QFUQ01C2H93 productive Homsap IGHV3-30*01 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVGDSSRPRGPFNYW in-frame + cctctggattcaacttcaatggctttaatatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttttgtcatatgatggaaataataagttctacgcagactccgtgagtggccgattcaccatctccacagacagttccaagaggacattgtttctgcaaatgaacaacctgacaactgaagacacggctctttattactgtgtgggggacagtagccggccccgggggccttttaactactggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 19108 JY8QFUQ01BHOG6 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19109 JY8QFUQ01CPPN6 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19110 JY8QFUQ01BX7KN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 149 89.19 33/37 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found tctctggattcacctttgacagctacgccatgagctg 19111 JY8QFUQ01CMRHA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CANEVGYCSG## out-of-frame + ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19112 JY8QFUQ01CW7IR productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 831 89.76 184/205 nt 88.78 182/205 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.37.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift)in FR3-IMGT, from codon 70 of V-REGION: 1 nucleotides (from position 107 in the user submitted sequence), (cause frameshift) tctctggtgactcccacttctggagctggatccggcagcccccgggaaagggcctggagtggattggttatgtctataacagtgggaccaccaactacaacccctcctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19113 JY8QFUQ01CVRLS productive (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaaTcccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19114 JY8QFUQ01B9X5T productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19115 JY8QFUQ01AEPNF unproductive Homsap IGHV3-30*01 F 873 89.4 194/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CACGHMRDGYDV## out-of-frame - ctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctgggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19116 JY8QFUQ01BPEHO unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 674 94.04 142/151 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat 19117 JY8QFUQ01BUXJ7 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19118 JY8QFUQ01A3QD4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19119 JY8QFUQ01B7OTL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19120 JY8QFUQ01BZVFM productive Homsap IGHV3-48*03 F 865 88.58 194/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame - gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19121 JY8QFUQ01CMP5A unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 7 X 8.7.X [4.17.38.11] CARGAPFS** (see Functionality comment) out-of-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19122 JY8QFUQ01CMMMF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19123 JY8QFUQ01B9RLH productive Homsap IGHV2-5*02 F 1170 97.95 239/244 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.17.38.11] CAHRRIRFGFDYW in-frame + gaccctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19124 JY8QFUQ01BBSUJ No results 19125 JY8QFUQ01BM3Q0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19126 JY8QFUQ01C3T5I unknown (see comment) Homsap IGHV3-48*03 F 810 86.18 187/217 nt 85.71 186/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttaCagttttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctgggccagggaaccctgtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 19127 JY8QFUQ01CCGC0 No results 19128 JY8QFUQ01AE9BM No results 19129 JY8QFUQ01BC03T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgagagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19130 JY8QFUQ01DIARZ productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19131 JY8QFUQ01DD50U unproductive Homsap IGHV4-61*02 F 870 88.64 195/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CARERSSSSGGTRELDS## out-of-frame + in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ctctggtggccccatcagcagtggtgcttactactggacctggatccggcagcccgccgggaaggggctggagtggatcggacgggtttatagaagtgGggtacaccgactacaatccctccctcaagagtcgagtcaccatgtcactagacgcgtccaatgaccagttctccctgaggttgaactctgtgaccgccgcagacacggccgtatattactgtgcgagagaacgtagtagctcgagtggcggaacgagagaacttgactcctgggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19132 JY8QFUQ01COTZA unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CASAPSDSSGYYFSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgggtccgacaggcccctgGgacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 19133 JY8QFUQ01B3XIV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 282 84.62 66/78 nt 8 X X 8.X.X [1.16.X.X] null + No rearrangement found Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcatttttagaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcga 19134 JY8QFUQ01CZ4RG productive Homsap IGHV3-64*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVTCGDYSYEYW in-frame + cctctggattcattttcagtacttatcctatgcactgggtccgccaggctccagggaagggactggaatatgtttcagctattagtcgtaatggggataacgcatattatgcagactctgtgaagggcagattcaccatgtccagagacaattccaagagcacactgtatcttcagatgggcagcctgagagctgaggacatggctgtgtattactgtgtgacatgtggtgattacagctatgagtactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19135 JY8QFUQ01CTA39 No results 19136 JY8QFUQ01BFRWU unproductive Homsap IGHV3-48*01 F (see comment) 754 84.04 179/213 nt 83.1 177/213 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 7 X 8.7.X [1.17.38.11] CSRDGRRGYDLDS## out-of-frame - Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagcccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19137 JY8QFUQ01CGONG productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1038 96.41 215/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19138 JY8QFUQ01C9OOD productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19139 JY8QFUQ01CCX7V No results 19140 JY8QFUQ01DTYSW No results 19141 JY8QFUQ01AYEYZ productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19142 JY8QFUQ01CM5IQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgccctggtccagggcttcttcccccc 19143 JY8QFUQ01C231C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGFYGDYPATWFDPW in-frame + ttctggactcacttttagcagccatgccatgagctgggtccgccaggctccagggatggggctggagtgggtctcagcccttaatgatcgtggtgataccacatactacgcggcctccgtgaggggccggttcaccatctccagagacaattccaagaacatgctgtttctacacatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagggcttctacggtgactacccggcgacgtggttcgacccctggggccagggaacgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19144 JY8QFUQ01CWJAZ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 769 82.67 186/225 nt 81.78 184/225 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-18*01 F 2 10 7 13 10.7.13 [3.17.38.11] CARHSRLVRYF*ILG in-frame - stop codons Low V-REGION identity (82,67% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tctctggtggctcccatccaacaaggtggtagttatcactgggcctggatccgccagtccccagggaaAggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtGccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtacttttgaattctgggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19145 JY8QFUQ01CQI78 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARKRVPGGNFLW#DYW out-of-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggaactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagccacagcggcccttgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19146 JY8QFUQ01B2UAC unknown (see comment) Homsap IGHV3-74*03 F 115 54.92 67/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found tctggattcaccttcagtagctactggatgcactgggtccgccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19147 JY8QFUQ01C96QO No results 19148 JY8QFUQ01DLQGA productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGGTFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19149 JY8QFUQ01CKRGF productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19150 JY8QFUQ01BR8YS productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19151 JY8QFUQ01AXQ9G productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + ctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19152 JY8QFUQ01B1LH3 unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.07 192/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagAaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19153 JY8QFUQ01DKLCW productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGDDILSGYSIDTW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cttctggatacactttcaccactcactggatcgcctgggtgcgccagatgcccgggaAaaggcctggcgtggatgggaatcatctttcctggagactctgagactagatacaacccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagtaccgcctacctgcagtggagcagcctggaggcctcggacaccgccatctactattgtgcgagaggggacgatatcttgagtggttattcaattgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19154 JY8QFUQ01C39FU unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-3*01 F 3 8 8 17 8.8.17 [2.17.38.11] CARILTLFAVVTSSGMDVW in-frame - stop codons Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) gcctctggattcacctttagcagccatcccatgagctgagtccgccaggctccagggaaggggctggagtgggtctcatccatcaccagtagtggtagttatgtctaccattcagactcaacgaagggccgattcaccatctccagagacaacgcccagaattcactatttctgcaaatgaacaacctgagacccgaggacacggctatatattactgtgcgaggatcctgacgctttttgcagtggttacctccagtgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19155 JY8QFUQ01AC0DP productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 1 10 7 12 10.7.12 [1.17.38.11] CARLTDWWGHFDHW in-frame - tctctggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtgggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 19156 JY8QFUQ01CIZLY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 895 90.74 196/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - tccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19157 JY8QFUQ01BCT8D productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19158 JY8QFUQ01BQWRG unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGGNGDLDY## out-of-frame + in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaGggggctggagtGgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgaccagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 19159 JY8QFUQ01BJVT6 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found cctctggattcatcttcagtagctactggatgcactggg 19160 JY8QFUQ01CZ8KV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [2.17.38.11] CARDNYGDYW# out-of-frame - gcctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaggc 19161 JY8QFUQ01ALS49 No results 19162 JY8QFUQ01B3S8M productive Homsap IGHV3-7*01 F 846 88.02 191/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRDRPGGWALDYW in-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19163 JY8QFUQ01DSY3R unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGRG# out-of-frame - in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagtcatgtcatgagctgggtccgGccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaAagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtcgggggggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 19164 JY8QFUQ01AMMCF No results 19165 JY8QFUQ01BKL8E productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 3 8 8 13 8.8.13 [1.17.38.11] CAKSPSQVGYYLDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtaccttTtggcatgcactgggtccgccaggctcccggcaAaggggctggagtgggtggcaatcatatcaaatgatggaagtaagaaatactacgcagactccgtgaagggccgattcaccatttccagagaaaattccgagaacacgctgtatctgcaaatgagcagcctgagagctgaggacacggctgtgtattactgtgcgaaatcaccctcccaagtgggctactacttagactgttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19166 JY8QFUQ01ADTZ7 No results 19167 JY8QFUQ01B9ZJQ productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNSLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagccCcccagggaagggactggagtggattgGgggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacagtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19168 JY8QFUQ01BVDHY productive Homsap IGHV3-30*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19169 JY8QFUQ01C1WET productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactgggaccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactca 19170 JY8QFUQ01B6LHF productive Homsap IGHV3-48*01 F 811 85.84 188/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CATDRLRGDKYNFDDW in-frame - ggctacggatttgtcttcagtggcactaatatgaattggctccgccaggctccagggaaggggctggagtggatttcacacattagtcacaatagtgaaaccatattctatgcagactctgtgaggggccgagtcaccatctccagagacaatgccaggaactcactgtatctgcacatgagcagcctgagagccgaggacacggcagtatattactgtgcgaccgaccgccttcgtggagataaatacaattttgacgactggggccagggaaccctggtcaccgtctccccagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19171 JY8QFUQ01CQ8UD productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.16.38.11] CARAIGRPFYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaagggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19172 JY8QFUQ01BMRSQ productive Homsap IGHV3-48*01 F 1054 98.17 215/219 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [2.17.38.11] CARDQVTEDYW in-frame - gcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccttggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19173 JY8QFUQ01A554Z productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtGacctatggcatgctctgggtccgccatgttgcaggcaaGggggctggagtgggtggcaactatatcagctgatggacgaaatCaaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19174 JY8QFUQ01BR8JQ unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CARGTRYNNGLD#FDVW out-of-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctGggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19175 JY8QFUQ01B7Y92 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'CG' (2 nucleotides at position 195 to 196 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggGAaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccCGggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19176 JY8QFUQ01DA6LQ productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSAPWNDHW in-frame + tctctggtggctccatcagcagcggttattactactggagctggatccggcagcccgccggggagggactggagtgggttgggcgtatctctgccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatatcagtgaacacgtccaagaaccagttctccttgaggctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagacaaggggacagtagtgctccctggaatgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19177 JY8QFUQ01DLBW7 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 966 92.83 207/223 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD1-26*01 F 3 8 10 14 8.10.14 [1.17.38.11] CTRDLSGSYSGAFDVW in-frame + atctggattcacctttggtgactttgctatgagctggtttcgccaggctccagggaaggggctggagtggctaggtttcattagaagcaaaatttatggtgggacaccagaatacgccgcgtctgtgaaaggcagatgtcccatctcaagagatgattccaaaaacatcgcctatctgcaaataaacggcctgaaaaccgaggacacagccatgtatttctgtaccagagatctcagtgggagctactccggtgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19178 JY8QFUQ01BZXH0 No results 19179 JY8QFUQ01AQDMW No results 19180 JY8QFUQ01AM1OS productive (see comment) Homsap IGHV4-61*02 F 929 91.4 202/221 nt 90.95 201/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARAWNGDYEVGWFDPW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); tctctggtgactccatcggtaatggaagttactactggagctgggtccggcagtccgccgagaagggactggagtggattggacatatctataccagAggggagcaccaactacaacccctccctcaagagtcgagtcaccatttcagccgacacgtccaagaatcagatctccctgaagttgacctctgtgaccgccgcagacacggccgtatattactgtgcgagggcgtggaacggtgactacgaggtgggctggttcgacccctggggccaggggaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19181 JY8QFUQ01C6P3H unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDV# out-of-frame + stop codons ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctgggccaagggacaatagtcaccgtctcctcaggcctccaccaagggcccatcggtcttccccctggcaccctcctccaaagcacctcctgggggcacagcggccctgggctggcctggtcaaggactacttccccgaaccggtgacggtgtctggaactca 19182 JY8QFUQ01BKVTV productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 657 78.34 170/217 nt 77.88 169/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggggttcaccatcagtcactactccatggcctGgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccttgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19183 JY8QFUQ01ABTVQ productive Homsap IGHV1-18*01 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-21*02 F 3 8 8 17 8.8.17 [0.17.38.11] CVREESIVVVTGRRGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccatgtattattgtgttagagaagagtcaattgtggtggtgaccgggcggcggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19184 JY8QFUQ01AXLNQ productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 19185 JY8QFUQ01CSTAE unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CTRPGVGGLFF##DFW out-of-frame - stop codons in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); gttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgggtggcgatcaCtctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtacgagaccaggagtggggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19186 JY8QFUQ01CC95Y productive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 91.71 199/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'TT' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); ctctggatTTtagcttttagaaccttttggatgagctgggtccgccaggctccagggagggggctggagtgggtggccaacatAaaagtcagatggaagtgacaaatggtatgtggactctgCtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19187 JY8QFUQ01AY0OW No results 19188 JY8QFUQ01BW1WP productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKELGRALTGNYYQYFHYW in-frame + ctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaattggggagggccctgactgggaactactaccagtactttcactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19189 JY8QFUQ01CBEK7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactggatgcactgggtccgccCaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19190 JY8QFUQ01A0DCS productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19191 JY8QFUQ01CHVJM productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 19192 JY8QFUQ01CWNDC No results 19193 JY8QFUQ01BF9XY No results 19194 JY8QFUQ01BHNKP No results 19195 JY8QFUQ01CB41Y productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 809 86.51 186/215 nt 85.12 183/215 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'TTT' (3 nucleotides at position 99 to 101 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctctggatttatcttcagtgattatagcatgaattgGggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtacTTTcgaatattacgcggGactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19196 JY8QFUQ01C3JVZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19197 JY8QFUQ01BD3GL productive (see comment) Homsap IGHV3-48*02 F (see comment) 672 78.18 172/220 nt 77.73 171/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gctctgggattcccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctcccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19198 JY8QFUQ01CPYHI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19199 JY8QFUQ01BUTOJ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19200 JY8QFUQ01CNYY7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttccccgaaccggtgacggtgtgcgtggaactca 19201 JY8QFUQ01BMXAH unknown (see comment) Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ2*01 F (see comment) 36 66.67 12/18 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgccca 19202 JY8QFUQ01DOX9C productive Homsap IGHV3-30*01 F 981 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNSGYNCW in-frame - ctctggattcaccttcagtcactatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatctgatgaaagtgataaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacaacctgacagatgaggacacggctgtgtattactgcgcgagagacaatagtggttataactgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19203 JY8QFUQ01BOGEI No results 19204 JY8QFUQ01AITVH productive Homsap IGHV3-11*01 F 846 88.02 191/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARDGDDYRSYYYGMDVW in-frame - ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19205 JY8QFUQ01CH0MW productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 921 90.58 202/223 nt Homsap IGHJ4*02 F (see comment) 231 97.92 47/48 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [2.17.38.11] CARDRLGSCSGASCPVYYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctctggtggctccatcaacagtggtgattcctcctggacctggatccgccagtacccagggaagggcctggagtggattgggtacatctctggcagtggggactcctactccaacccggccctcaagagtcgagttaccatatcagtggacacgtctaagagccagttcttcctggaactgagttctgtgactgccgcggacacggccgtctattactgtgcgagagatcggctgggatcttgtagtggggctagctgccccgtctactactttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19206 JY8QFUQ01BQDHE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag 19207 JY8QFUQ01CQJQW unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - tccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19208 JY8QFUQ01CQ0GJ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 917 92.09 198/215 nt 91.16 196/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgactgggtccgccaactccgggggagggggctgagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 19209 JY8QFUQ01B2QLD No results 19210 JY8QFUQ01CJ25K No results 19211 JY8QFUQ01CJWDI productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19212 JY8QFUQ01AO8O3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19213 JY8QFUQ01DXHPU No results 19214 JY8QFUQ01DHZXV No results 19215 JY8QFUQ01B0W2M productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 19216 JY8QFUQ01BXDPP productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMSYYGMDVW in-frame - catctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgtcttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19217 JY8QFUQ01ANM6A No results 19218 JY8QFUQ01B4H18 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19219 JY8QFUQ01B7KDD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 732 82.71 177/214 nt 82.24 176/214 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B7KDD ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (82,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggGggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagaaggccgattcaacatctccagggacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19220 JY8QFUQ01ARNJT No results 19221 JY8QFUQ01COA0U productive Homsap IGHV2-5*02 F 1116 95.49 233/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CAHIRAELSTSCHAFW in-frame + gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaaggccctggagtggcttgcacttgtttattgggatgatgataagcgctacagctcatctctgaagagcagactcaccatcaccaaggacacctccaaaaaccaggtggtccttacaatgactaacatggaccctatggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19222 JY8QFUQ01B702Z unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 639 76.96 167/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (76,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19223 JY8QFUQ01AKNSQ productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame + ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19224 JY8QFUQ01B2QMW productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19225 JY8QFUQ01CB4PE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19226 JY8QFUQ01A6CYA unproductive (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F (see comment) 409 80.16 101/126 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 X 4 X X.4.X [X.X.38.11] CASFAGPVVVTL*WLLVRLT#YCDYR out-of-frame + stop codons Low V-REGION identity (80,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgcattcaccgtcagtaggctccgtgacgggccgagtcatcatctccagagagaatgcccagaactccgtgtatcttccactgaacagcctgagagccgggaacacggctgtgtatcactgcgcaagttttgctggccctgtggtggtgactctatagtggctgttggtccgtctgaccactactgtgactaccggggcctgggaaccccggtccccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19227 JY8QFUQ01CGCX3 productive (see comment) Homsap IGHV4-61*02 F 1004 95.87 209/218 nt 94.5 206/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 9 7 17 9.7.17 [1.17.38.11] CARAPESSVYYLRGGFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'CTT' (3 nucleotides at position 28 to 30 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) tctctggtgactccatcaacagtggtaCTTactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggaccaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtggacacgtccaagaaccagttctccctcaagctgacctctgtgagcgccgcagacacggccgtgtactactgtgcgagagcgcctgagagtagtgtttattacctcaggggcggctttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagataggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19228 JY8QFUQ01DDMDO No results 19229 JY8QFUQ01BJVZ3 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 871 88.29 196/222 nt 87.84 195/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [3.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); aggcctcctggattcaCcctttggttattatggcatggactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19230 JY8QFUQ01DGH6B unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 489 82.98 117/141 nt 8 8 X 8.8.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (82,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactcag 19231 JY8QFUQ01CYS7P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19232 JY8QFUQ01CZ6B1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19233 JY8QFUQ01A6IZH productive (see comment) Homsap IGHV3-7*01 F 891 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgagGaaaaactttgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19234 JY8QFUQ01AJFJ5 unknown (see comment) Homsap IGHV3-23*05 F 91 51.82 71/137 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccga 19235 JY8QFUQ01BTJDV productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgagacag 19236 JY8QFUQ01CRUAF productive (see comment) Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 844 88.73 189/213 nt 88.26 188/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-7*01 F 1 8 8 9 8.8.9 [0.16.38.11] CVIKTSYYDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) tggaggcaccttcaacaccattacttttagttgggtgcgacaggcccctggacaagggctcgagtggatgggggggtcatccctctctttagtagaacaaattacgcagaaaacttccagggcagagtcacaattaccgcggacaagtccacgaccacagcctacatggagttgagcagcctgagatttgaggacacggccatgtattactgtgtgatcaaaactagttattatgactactggggcctgggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19237 JY8QFUQ01ATVO9 No results 19238 JY8QFUQ01BGBEV productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'GA' (2 nucleotides at position 25 to 26 in the user submitted sequence), (cause frameshift); agtctctggattcaccgtcaatagGAaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacgcggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19239 JY8QFUQ01B8YFN productive (see comment) Homsap IGHV3-7*01 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARVNKDSTDMW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaaGgggggctggagtgggtggccagcataaaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccggaccagccccgaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtccatcgcctgccctggtccagggcttcttcccccc 19240 JY8QFUQ01A2CO4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19241 JY8QFUQ01B0UBH No results 19242 JY8QFUQ01AFB9Q productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD1-26*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARDREGARGYGMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagctatagcatgaactgggtccgccagactccagggaaggggctggagtgggtctcatcccttagtagtggtagtatttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagtcactatatctgcaaatgaacagcctgagagccgaagacacggctatatattattgtgcgagagatcgggagggagctagaggttacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19243 JY8QFUQ01A9EPX productive (see comment) Homsap IGHV3-7*01 F 835 87.44 188/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 7 8 12 7.8.12 [1.16.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 24 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ctctggattcagttttagtgacttttgatgcactgggtccgccaggcnccagggaaTggggctggagtggtggcccacntgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 19244 JY8QFUQ01CBP0J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-11*01 ORF 3 8 8 15 8.8.15 [1.17.38.11] CAKCDGVTVTKCYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagttttgccatgagttgggtccgccagcctccagggaaggggctggagtggatctcaactgtgactggtagtggaacttccacatactacgcagactccgtgaagggccacttctccatctccagagacaattccaagaaaacgctgaatctgcacatgaacagcctgacggtcggagacactggcttatattactgtgcgaaatgcgatggggtgacagtgactaagtgctactttgactcctggggccagggaaccctggtcaccgtctccccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19245 JY8QFUQ01C3JWV unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*05 F 161 54.49 97/178 nt 8 7 X 8.7.X [1.17.25.X] null + No rearrangement found cctctgcattcaccttcagtagctacgacatgcactgggtccgccaagcaacaggaagaggtctggagtgggtctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19246 JY8QFUQ01DC4HY unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTLR#DYW out-of-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttgcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19247 JY8QFUQ01BUREX productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcCccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 19248 JY8QFUQ01BWJ7A productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaAaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattattgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacatggtcatcgcctgcctggtccagggcttcttccccca 19249 JY8QFUQ01BCUIZ unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 724 85.35 169/198 nt 84.34 167/198 nt 8 2 X 8.2.X [2.17.37.X] null - No rearrangement found stop codons in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 88 in the user submitted sequence), (do not cause frameshift) gtctgtggtgggtccttcagtggtttctacCtagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19250 JY8QFUQ01DCHNV productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19251 JY8QFUQ01A4IA0 unproductive Homsap IGHV2-5*02 F 1134 96.31 235/244 nt 95.9 234/244 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 1 10 7 X 10.7.X [9.17.38.11] CAHRSFYGDYVFD#PG out-of-frame + in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaacttctctgggttctcactcaccactaGggggaatgggtgtgggatggatccgccagcccccaggaaaggccctggagtggcttgcactcatttattgggatgatgataagcgatacaggccatctctgacgagcaggctcaccatcaccaaggacacctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacagatcgttctacggcgactacgtcttcgaccccctggggcccgggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc 19252 JY8QFUQ01C6P1B productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19253 JY8QFUQ01CIXG9 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19254 JY8QFUQ01BLM96 unknown (see comment) Homsap IGHV3-7*03 F 968 94.04 205/218 nt 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagCtccccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccaggggaacccctggtcaacgtctcatcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctcccc 19255 JY8QFUQ01BJ9AX productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 8 9 8.8.9 [1.17.38.11] CARDNYGDYWG in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaacgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19256 JY8QFUQ01CLG1V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKRRGGYYIDFDYW in-frame + cctctggattcacctttactagttacagtttcaattgggtccgccaggctccagggaaggggctggagtgggtctcaactatcaatactagtggtagtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacgaggtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaagcggaggggtggttattacatcgactttgactactggggccagggaacgctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19257 JY8QFUQ01APUSH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19258 JY8QFUQ01CDEJB No results 19259 JY8QFUQ01CS32Q productive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcacctttcatgattataccatgcactGgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 19260 JY8QFUQ01CDPLW No results 19261 JY8QFUQ01BH5JB productive Homsap IGHV4-61*03 F (see comment) 782 85.12 183/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD4-17*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARNDHGMWDAFHLW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01BH5JB ; 10 AA in Homsap_IGHV4-61*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgactctatggcaagctattactggagttggctccggcagcccccaggggagagactggaatggattgggtacatatattccactgggagcaccaactacaacccctcctttaagagtcgagtcaccatttcaatagacaccccgaagaaccacctctccctgaaattgaaatctgtgaccgctgcagacacggccgtgtatttttgtgcgaggaacgaccacggtatgtgggatgcatttcatctctggggccaagggacactggtcaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19262 JY8QFUQ01BH0Y7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt 84.33 183/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19263 JY8QFUQ01CROIY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccgcggcgcactagtcacagtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 19264 JY8QFUQ01ANE0F No results 19265 JY8QFUQ01CQ8WJ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 122 55.12 70/127 nt 8 8 X 8.8.X [1.17.8.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 19266 JY8QFUQ01ABJNQ productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19267 JY8QFUQ01CBUUD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame + ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19268 JY8QFUQ01AUA3S No results 19269 JY8QFUQ01CJLGS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatGgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19270 JY8QFUQ01A2FLM unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSVPRASEAAYHFDY## out-of-frame + cctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattgggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19271 JY8QFUQ01B4XWG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19272 JY8QFUQ01A2EKG productive (see comment) Homsap IGHV3-9*01 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); tctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgGggtctccggtatcactgggaatagtggttccataggcGtatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19273 JY8QFUQ01CGA3R No results 19274 JY8QFUQ01B0VB9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 823 87.04 188/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + tctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatcttcagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19275 JY8QFUQ01CA6ON productive Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 19276 JY8QFUQ01B2Y4F unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 650 85.71 150/175 nt 8 8 X 8.8.X [2.17.23.X] null + No rearrangement found gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgc 19277 JY8QFUQ01CWOSR productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19278 JY8QFUQ01ALTMD unproductive Homsap IGHV3-48*03 F 824 86.7 189/218 nt 86.24 188/218 nt Homsap IGHJ5*01 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDKGWSGYGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctgggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggGggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 19279 JY8QFUQ01B9180 No results 19280 JY8QFUQ01BWUNA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19281 JY8QFUQ01CXBZN unproductive Homsap IGHV1-3*01 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*02 F 1 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNG#DFW out-of-frame + tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacgggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 19282 JY8QFUQ01CA9GA productive (see comment) Homsap IGHV4-55*03 P (see comment) 734 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 9 7 15 9.7.15 [1.17.38.11] CARDQSVYTAGSYFDSW in-frame + Potentially, because of detected insertion/deletion however the closest V is a pseudogene Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); tctctggtgactccatgagtagcgacacgtggtggagctgggtccgccagacgccagagaagggactggaatggattggggagatcaatcaaagagggacgacctcctacaacccgtccctcaggagtcgagtcgtcctgtcagtgggcgagtccaaaaaGtcaattctccctgaggctgacctctgtgaccgccgcggactcggccatctattattgtgcgagagatcagtctgtctatactgcgggaagttactttgactcctggggccagggaacgctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19283 JY8QFUQ01AS6RF unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgcctgagcctcgacagcaccccccgaagatggaacgtcggtcgtcgcatgcctggtccagggcttcttccccca 19284 JY8QFUQ01DOAEK unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggtaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctcggtccagggcttcttcccccga 19285 JY8QFUQ01BJ238 productive (see comment) Homsap IGHV4-61*02 F 870 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*02 F 101 64.71 33/51 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [2.17.37.11] CARDFGGSYNLVATG in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtagtgattctcattactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttntgtgcgagagattttggaggttcctacaatttagtggctactgggggcaggggaaccctggtcaccnnctccctcaggcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19286 JY8QFUQ01BBNSY No results 19287 JY8QFUQ01B9LZA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19288 JY8QFUQ01DK3MS productive Homsap IGHV1-24*01 F 988 96.24 205/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 19289 JY8QFUQ01CL5LY productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 19290 JY8QFUQ01AFS5H unproductive (see comment) Homsap IGHV3-9*01 F 810 86.18 187/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVKDRKSWWLQSV#DAFDIW out-of-frame - stop codons ctctggattcaccttcgacgactatgtcatgcattgggtccggcaagttccagagaggggcctggagtgggtcgcaggcattaatggggaaagtaatagttttggctctgtggactctgtaaagggccgattcaccatctccagagacaaggccaagaataccctgtatttgcaaatgaatagcctgagagttgaggacacggccttgtattattgtgtgaaagatagaaaaagctggtggctacaatctgttggatgcttttgatatctggggccaagggacaatggtcaccgtcgcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19291 JY8QFUQ01B7C5Q unknown (see comment) Homsap IGHV3-16*01 ORF, or Homsap IGHV3-16*02 ORF or Homsap IGHV3-19*01 P or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-35*01 ORF or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 139 88.57 31/35 nt 8 X X 8.X.X [1.2.X.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaac 19292 JY8QFUQ01AI4LK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19293 JY8QFUQ01AXYU7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1031 97.25 212/218 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGPHQYYFDY## out-of-frame + cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggttggagtgggtctcaactattagtggtagtggtggtaggacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19294 JY8QFUQ01APQJP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tctccggattcacctttactaattattggGatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacAaaactacgcggactccgtggGaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 19295 JY8QFUQ01BNYRB No results 19296 JY8QFUQ01AHTJQ No results 19297 JY8QFUQ01A58QT productive (see comment) Homsap IGHV3-7*01 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19298 JY8QFUQ01BBL4C productive (see comment) Homsap IGHV3-11*01 F 980 95.35 205/215 nt 94.88 204/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-1*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARVNTWNADYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 3 nucleotides (from position 105 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctggagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggataacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggccatttattactgtgcgagagtgaacacatggaacgccgactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19299 JY8QFUQ01B0KHU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactc 19300 JY8QFUQ01BE293 unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 19301 JY8QFUQ01AETK0 productive (see comment) Homsap IGHV3-7*01 F 918 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaacnattggatgacctgggttcgccagGgctccagggGAaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatccgctcttacccccgtggcgccctgctcccaggagccacctccgagaggcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19302 JY8QFUQ01CJV6U productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [0.17.38.11] CVKDISRSGCFEYW in-frame - ctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19303 JY8QFUQ01DUQO7 No results 19304 JY8QFUQ01ASNDA No results 19305 JY8QFUQ01CLS2T unknown (see comment) Homsap IGHV3-23*05 F 135 55.56 75/135 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons cctctgggttcacctttagcagctatgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19306 JY8QFUQ01AR158 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVRGGSQWGPSGGGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgataGgttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagaggggggagtcagtgggggccttcaggtggggggtttgactactgggggccagggaaccctggccaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcaggc 19307 JY8QFUQ01AMNX3 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19308 JY8QFUQ01ACE1O productive Homsap IGHV4-39*07 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 2 9 7 16 9.7.16 [1.17.38.11] CARAVLDNAWPIYYDFWG in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (9 AA in JY8QFUQ01ACE1O ; 10 AA in Homsap_IGHV4-39*07), and low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccatcaccacttggcattactggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttgggggcccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19309 JY8QFUQ01AHDG8 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 595 82.66 143/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (82,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgc 19310 JY8QFUQ01BZKHD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.16.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggaTttcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19311 JY8QFUQ01BCZUP productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19312 JY8QFUQ01DWIRJ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcaccttcaggagttatatcatgaactgg 19313 JY8QFUQ01CUUUD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19314 JY8QFUQ01C6FIQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19315 JY8QFUQ01C9HBL productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19316 JY8QFUQ01BLKNY productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 957 94.39 202/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [0.17.38.11] CAKEQEPHGHYVGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); tggattcGaccttcagtaGgctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19317 JY8QFUQ01B1UYR productive Homsap IGHV3-21*04 F (see comment) 662 78.44 171/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccggtttcatcttcagtcacttcagcatgaactgggtccgccaggctccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19318 JY8QFUQ01A8C2S productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgtgtctgtggaactcag 19319 JY8QFUQ01AOJC3 unproductive Homsap IGHV3-7*01 F 969 93.64 206/220 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + agcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19320 JY8QFUQ01BEH1V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); gtctcggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgcCacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19321 JY8QFUQ01BGBZ4 unproductive Homsap IGHV3-11*01 F 846 88.02 191/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CADINWV#WCFDLW out-of-frame + ctctgaaatcaccttcagcgaccactacatgagctggatccgccaggctccaggaaaggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaactgggtgactggtgcttcgatctctggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19322 JY8QFUQ01B71JV productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + ctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19323 JY8QFUQ01AJSTD unproductive (see comment) Homsap IGHV3-21*04 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRAGVRELIG#FDCW out-of-frame + stop codons cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagtagtagtggttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctggcagccgaggacacggccttatatcactgtgtgagagcaggggttcgggagttgatcgggctttgactgctggggccagggaaccctggtcaccgtgtccctcaggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19324 JY8QFUQ01CFHQE unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19325 JY8QFUQ01A3XIT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CG' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcCGgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19326 JY8QFUQ01A8802 No results 19327 JY8QFUQ01B1MND unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CVRGGLRWRPRTLLRP#YGLDVW out-of-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagagggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19328 JY8QFUQ01DGGA3 productive (see comment) Homsap IGHV3-9*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [2.17.38.11] CAKDIGVHMWTIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); gcctctggattcacGatttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaaagatattggggtacacatgtggaccattgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19329 JY8QFUQ01DDL8Y productive Homsap IGHV3-13*01 F 934 93.43 199/213 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-8*02 F 2 8 7 11 8.7.11 [1.17.38.11] CARWTAGCAFDIW in-frame + tctggattcaccttcagtacctacgacatgcactgggtccgccaagttacaggaaaaggtctggagtgggtctcagctatcggttttgctggtgacacttactattcaggctccgtgcagggccgattcgccatctccagagacaatgccaggaactccttgtatcttcaaatgagcagcctgagagccgaggacacggctgtctattactgtgcaaggtggacagctggttgtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19330 JY8QFUQ01APLKP productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [2.17.38.11] CASGGYSGSGEYFLRW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gcctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggGctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca 19331 JY8QFUQ01C8B7F productive (see comment) Homsap IGHV3-48*01 F (see comment) 774 84.33 183/217 nt 83.41 181/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [2.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) agcctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggGAaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 19332 JY8QFUQ01B2NHE productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19333 JY8QFUQ01BK370 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 757 83.11 182/219 nt 82.19 180/219 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-16*02 F 3 7 7 X 7.7.X [2.17.38.11] CTGLTYPDDY## out-of-frame - Low V-REGION identity (83,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 84 in the user submitted sequence), (cause frameshift) acgtgctggactttaccttcagtaagttctgatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactgggggccagggatgtttggccaccgtctcctcagcatccccgaccagcccccaaggtcttccccgctgagccccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19334 JY8QFUQ01B6ICN productive (see comment) Homsap IGHV3-7*01 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) ctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19335 JY8QFUQ01CX9L2 productive (see comment) Homsap IGHV3-33*03 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); gtctggattGcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19336 JY8QFUQ01B1RZ8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19337 JY8QFUQ01BDK5R productive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19338 JY8QFUQ01AQTGO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19339 JY8QFUQ01AGEVS productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1030 95.56 215/225 nt 94.67 213/225 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*02 F 1 10 9 10 10.9.10 [1.17.38.11] CARDYRWAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 131 to 131 in the user submitted sequence), (cause frameshift); tccggggacaatgtctctagcaatactgtttcttggaactggatcaggcagtGccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggggtaatgattatgcagtatctgtgGaaaagtcgaataaccatcaacccagacacatccaagaaccaggtctccctgcagctgaactctgtgactcccgacgacacggctgtttattactgtgcaagagattaccggtgggcttttgatatctggggccaagggacattggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19340 JY8QFUQ01DAV05 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.16.38.11] CAKDQSCIVGPCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaagggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19341 JY8QFUQ01C0LID productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggAaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19342 JY8QFUQ01CWEZK unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 779 83.94 183/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19343 JY8QFUQ01COOTC productive (see comment) Homsap IGHV4-61*02 F 834 86.82 191/220 nt 86.36 190/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 9 7 15 9.7.15 [1.17.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) tctctggtgcctccataataggggtaattattactggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19344 JY8QFUQ01BZU7C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19345 JY8QFUQ01ATJIB productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19346 JY8QFUQ01CUAZE No results 19347 JY8QFUQ01AZD7R unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGCKQWL#DAFDFW out-of-frame + ctctggattcatctttagtagctatgccatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtgccagtggtaagagcacatactacgcagactccgtgaagggccggttcagcatctccagagacaattccaagaacacgatgtctgtgcaaatgagcagcctgagagccgaagacacggccatatattactgtgcgaaaggttgcaagcagtggctgatgatgcttttgatttctggggccaagggacaatggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19348 JY8QFUQ01DB08D unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 X 8.8.X [2.17.38.11] CANASPPYNWN#YFYYYGMDVW out-of-frame + gcctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctcccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctggcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 19349 JY8QFUQ01B58W5 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame + gtctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgctagtactacttccatacactatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctgtcaccgttacctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttcc 19350 JY8QFUQ01AJAPB productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19351 JY8QFUQ01AP7IU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19352 JY8QFUQ01AD1EE unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1000 95.43 209/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [2.17.38.11] CARDTLEVVSNMDDAFDVW# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaacgggctggagtggatctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctgggggcccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19353 JY8QFUQ01BJDA8 No results 19354 JY8QFUQ01ABO2E unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 953 93.95 202/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.17.38.11] CAVSTTTWG#WFDPW out-of-frame - tctatggtgggtccttcagtggttactactggagctggatccgccagcccccaggggaggggctgcagtggattggaagagtcaatcatagtggaagcaccagctacaacccgtccctcaagagtcgagtcaccatgtcactagacacgtccaagacccacttttccctgaagctgacctctgtgaccgccgcggacacggctgtgtattactgtgcggtgtctactaccacctggggggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19355 JY8QFUQ01AU9OQ unproductive (see comment) Homsap IGHV4-61*02 F 902 90.05 199/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [1.17.38.11] CAREK**SV#NWFDPW out-of-frame + stop codons tctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19356 JY8QFUQ01CMBQL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1057 98.62 214/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARHAQYYYDSSGYYYLDYW in-frame - ttctggatacagctttaccagctactggatcggctgggtgcgccagatgcccgggaaaaggctggantggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgagacacgcgcagtattactatgatagtagtggttattactacttagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19357 JY8QFUQ01BIVHX productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttccccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactc 19358 JY8QFUQ01BUUP8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttatcaactatggcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19359 JY8QFUQ01CG36J unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1045 97.72 214/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKSGVGAT#YFDYW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'TA' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); gcctctggattcacatttTAggcagctatgccatgAagctgggtccgccaggctccagggaaTGgggcttggagtgggtctcagctattagtggtagtggtggtggcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagtcaggggtgggagctacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19360 JY8QFUQ01A7LJV productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 674 79.53 171/215 nt 79.07 170/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (79,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 99 in the user submitted sequence), (do not cause frameshift) cctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctaaagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtnttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 19361 JY8QFUQ01B7U9F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctcgggattcaccttcagtggctatagcatgaactgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactcag 19362 JY8QFUQ01CMLY6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - agcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19363 JY8QFUQ01B9UPL productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19364 JY8QFUQ01DDX1E unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 393 87.25 89/102 nt 85.29 87/102 nt 8 8 X 8.8.X [1.15.1.X] null + No rearrangement found in FR2-IMGT, from codon 45 of V-REGION: 4 nucleotides (from position 49 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) ctctggattcacctttaatagctttgccatgagttgggtccgccagtcagggaggggctgagtgggtctcagccattagtggcagtggtagtcggacatatt 19365 JY8QFUQ01CPQED No results 19366 JY8QFUQ01DC8OC productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgngcctcgacagcaccccccgaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19367 JY8QFUQ01CI4NV productive (see comment) Homsap IGHV4-39*03 F 902 90.0 198/220 nt 89.09 196/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'TT' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaAaattattattggggctggatccgccagccccccagggaagggttTTggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19368 JY8QFUQ01CPEF3 unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 271 65.07 95/146 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found Low V-REGION identity (65,07% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19369 JY8QFUQ01B0F0W productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 968 94.04 205/218 nt Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDAFEMW in-frame + cctctggattcacctttgatgattttggcatgagttgggtccgccaagttccagggaaggggctggagtgggtcgctggtatcagttggaatggaggcaaaacaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcattggtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19370 JY8QFUQ01ARB7K unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDFTYAFDL## out-of-frame + gtctggattcacgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctggggccaaggggacaatggtcaccgtctcttcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 19371 JY8QFUQ01CDDDZ productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 19372 JY8QFUQ01CPBGH productive (see comment) Homsap IGHV3-7*03 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARRVWGYKIGFPSYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggacCtctgtgaagggccgattcaccatctccagggacaacgccaggaactcagtgtatctgcaaatgaacagcctgggagccgacgacacggccgtgtattactgtgcgaggcgggtgtggggatacaaaattggattcccttcgtattactttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19373 JY8QFUQ01DUFLK productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcccccagggaaggGggctggagtggattggacaaatccatcatgtggggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19374 JY8QFUQ01CCTL0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19375 JY8QFUQ01CB8J6 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggccaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19376 JY8QFUQ01AM0T6 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcgGgtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19377 JY8QFUQ01AJQEI productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19378 JY8QFUQ01BAJM3 No results 19379 JY8QFUQ01CN1RC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 744 82.27 181/220 nt 81.36 179/220 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [2.17.38.11] CARYRVGDSLYYGLDGW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 93 to 95 in the user submitted sequence), (do not cause frameshift); agcctctggattcatttttagaaAattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19380 JY8QFUQ01CP221 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19381 JY8QFUQ01DDTOX productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 82.35 182/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 175 to 175 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccCctgaggctgaacgatgtgaccgctgcggacacggcCcatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcacccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc 19382 JY8QFUQ01A8FM1 productive (see comment) Homsap IGHV1-24*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD3-16*01 F 2 8 8 11 8.8.11 [0.17.38.11] CVGDVGWGYPQGW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); cggatacaccctcaatgaattatccatgcactgggtgcgacagactcctggaaaagggcttgagtcgatgggcggAttttgatcctgaatatggtaaaacaatctacgcgcagaagttccagggcagagtcaccatgaccgaggacacatctgcagacacagcctacatggagttgagaagcctgagatttgaggacacggccgtgtattattgtgtcggagatgtcggctggggatacccccaaggctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19383 JY8QFUQ01AJU4U productive (see comment) Homsap IGHV3-7*01 F 1017 96.77 210/217 nt 96.31 209/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19384 JY8QFUQ01CZRZK unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 947 92.31 204/221 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [2.17.38.11] CARDQSLGDA#EAFDIW out-of-frame - stop codons cagcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctgggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19385 JY8QFUQ01AP7PU productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19386 JY8QFUQ01BSZBN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19387 JY8QFUQ01CGFHV productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattcacctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19388 JY8QFUQ01B6OUF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame - cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19389 JY8QFUQ01A0C4X productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame - ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19390 JY8QFUQ01AICLR unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.12 203/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19391 JY8QFUQ01B4XRW unknown (see comment) Homsap IGHV3-7*02 F 104 50.0 109/218 nt 49.54 108/218 nt Homsap IGHJ1*01 F (see comment) 17 71.43 5/7 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); cctctggtttcacctttagtaacgattggatggactgggtccgccaggctccaggggaaGGgggctggagtgggtggccaatataaaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19392 JY8QFUQ01BFQS4 No results 19393 JY8QFUQ01B5DD0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19394 JY8QFUQ01ARWJL unknown (see comment) Homsap IGHV3-72*01 F 111 53.79 71/132 nt 8 10 X 8.10.X [1.17.7.X] null + No rearrangement found stop codons cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19395 JY8QFUQ01CQIMH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19396 JY8QFUQ01BLY7Y unproductive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtgttCaactgatggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19397 JY8QFUQ01BFO9X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19398 JY8QFUQ01AF7B4 unproductive Homsap IGHV4-39*07 F 787 85.19 184/216 nt 84.26 182/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [1.16.38.11] CARAVLDNAWPIYYDF## out-of-frame - in CDR1-IMGT, from codon 38 of V-REGION: 4 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcaccacttggcattactgggctggatccgccagcccccaggggagggtctggatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19399 JY8QFUQ01AEI8C productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame - tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19400 JY8QFUQ01AIEY8 productive (see comment) Homsap IGHV4-61*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.37.11] CARNPSYSNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgagaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaaccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19401 JY8QFUQ01BBAED unproductive (see comment) Homsap IGHV4-59*02 F (see comment) 755 83.72 180/215 nt 82.33 177/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD3-22*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDGQ*EVITLLKPW in-frame + stop codons Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 36 of V-REGION: 'TGGAAAA' (7 nucleotides at position 23 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagTGGAAAAttcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccCctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggccaatgagaggttattactcttttgaaaccctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19402 JY8QFUQ01CWZ29 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1066 99.54 215/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 1 8 7 9 8.7.9 [2.17.38.11] CARDTWPTSYW in-frame - gtctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacactgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatacctggccaacttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19403 JY8QFUQ01B4A1V productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19404 JY8QFUQ01ACOK8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame + gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctctaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19405 JY8QFUQ01DL1RO No results 19406 JY8QFUQ01BCXFL No results 19407 JY8QFUQ01B54T1 unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1105 100.0 222/222 nt 99.55 221/222 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.37.11] CTKCSVTIYFFGLL# out-of-frame + stop codons in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 19408 JY8QFUQ01ANIFJ productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19409 JY8QFUQ01CU3J4 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [2.16.38.11] CARHSRLVRYFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagcagtagttcttactactgggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19410 JY8QFUQ01BOE49 unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ5*01 F 111 68.63 35/51 nt 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccaggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19411 JY8QFUQ01BFAKE productive Homsap IGHV3-7*01 F 904 91.2 197/216 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + tctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19412 JY8QFUQ01A7GG5 No results 19413 JY8QFUQ01CVM2Y productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19414 JY8QFUQ01CB4HP No results 19415 JY8QFUQ01A33U2 productive (see comment) Homsap IGHV4-39*03 F 893 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 73 to 75 in the user submitted sequence), (do not cause frameshift); tctccggtggctccatcaacagtagaaAattattattggggctggatccgccagccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19416 JY8QFUQ01DM0IQ No results 19417 JY8QFUQ01CPVUP productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcatcgcatgcctggtccagggcttcttccccca 19418 JY8QFUQ01ATMY1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19419 JY8QFUQ01CJLF6 productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + tctctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19420 JY8QFUQ01C1AXI No results 19421 JY8QFUQ01BIXG5 productive Homsap IGHV3-11*01 F 954 93.55 203/217 nt Homsap IGHJ2*01 F (see comment) 211 88.68 47/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [1.17.38.11] CADIRLGDWCFDIW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgaccactacatgagttggatccgccaggctccagggaaggggctggagtggatttcatatattagtactagtggtaatatgatttattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcagatgaacagcctgagagccgaggacacggccgtctatttctgtgccgatataagactgggtgactggtgcttcgatatctggggccggggcaccctggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19422 JY8QFUQ01AP8C2 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 975 93.27 208/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19423 JY8QFUQ01B1R7J No results 19424 JY8QFUQ01CJSEU productive Homsap IGHV3-7*01 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAREQSSRGYPLDYW in-frame + ctctggattcacctttgagacttattggttgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatacccacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19425 JY8QFUQ01DD2AN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19426 JY8QFUQ01BWQWD unproductive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFEYW# out-of-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggcccaggggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19427 JY8QFUQ01B82FV unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggGggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19428 JY8QFUQ01B5T5L unproductive Homsap IGHV1-2*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDGISMTLVRGVRPFDY## out-of-frame + tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactgggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19429 JY8QFUQ01CDGFM No results 19430 JY8QFUQ01BO56U productive Homsap IGHV3-30*10 F (see comment) 734 82.11 179/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19431 JY8QFUQ01CUNKR unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 434 77.03 114/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (77,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctacgtggtcgtcgcatgcctggtccagggcttcttccccca 19432 JY8QFUQ01DC9KF unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); gcctccggattcaccGtttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19433 JY8QFUQ01BU67O productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19434 JY8QFUQ01CFRCL productive (see comment) Homsap IGHV3-48*01 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 8 8 15 8.8.15 [1.16.38.11] CATVPRRGTGGYYLASW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagcCtatcccatgacctgggtccgccaggctcctgggaagggctggagtgggtttcatacattagtagtagtggtagaaccatttcctacgcggactctgtgaagggccgattcagcatctccagagacaatggcaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgcgacagttccccggcgggggaccggtggttattaccttgcctcttggggccagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19435 JY8QFUQ01ANXYC productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 926 92.56 199/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame - tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggctgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19436 JY8QFUQ01AZN62 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19437 JY8QFUQ01C4BQP No results 19438 JY8QFUQ01BG2JH No results 19439 JY8QFUQ01AOQG2 productive Homsap IGHV1-3*01 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGESLGGDYFDYW in-frame + tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctggcacgggtaacacaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19440 JY8QFUQ01DLCEW productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagtgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19441 JY8QFUQ01AMS4U productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgctggtccagggctctt 19442 JY8QFUQ01B2MMM productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19443 JY8QFUQ01CKQ2N productive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggttgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctcccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19444 JY8QFUQ01CCHD0 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 19445 JY8QFUQ01BBUHG No results 19446 JY8QFUQ01BPM6Q unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 19447 JY8QFUQ01BPRI6 productive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 962 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctatgcGtatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgnatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 19448 JY8QFUQ01CBYV8 No results 19449 JY8QFUQ01CESVQ No results 19450 JY8QFUQ01CB9GM unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 917 92.09 198/215 nt 91.63 197/215 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CAKKLTIGSQLLLQRFGRM# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'CA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift); tctctggtggcctcatcagtaattactattggacctggatccggcagcccccaggaaagggCAcatggagtggattgggaacatctattacagtgggagcgccacctacaacccctccctcaagagtcgagtcaccatatcaatagactcgtccaagaaccagttctccctgaggctgaccgctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaaacttacgattgggtcacagttacttctacaacgctttggacgtatgggggccaagggaccacggtcaccgtcgcctcaacatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 19451 JY8QFUQ01B9PJJ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 112 53.73 72/134 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19452 JY8QFUQ01BGUIW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacaacctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19453 JY8QFUQ01CDP6X No results 19454 JY8QFUQ01AFSCA unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARKRVPGGTFYGGLL# out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatgggggactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19455 JY8QFUQ01A6QRO productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); gcctctacattcacgtttagtcggtattggatgagctgggtAccgccaggctccagggaagggcctggGagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19456 JY8QFUQ01BVQW1 No results 19457 JY8QFUQ01BZ4RA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 97 66.0 33/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGAGAEGKGGMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19458 JY8QFUQ01B5QDY productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 19459 JY8QFUQ01B4Z9U productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.37.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 194 in the user submitted sequence), (cause frameshift) ttctggatacacatttatgaattattggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccaacaccgcctacgtgcagtggagcagcctgaaggcccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19460 JY8QFUQ01A8DBN productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19461 JY8QFUQ01AD3VH unproductive Homsap IGHV4-59*03 F (see comment) 728 82.33 177/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-9*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREDPYFRHFDWIS##DPW out-of-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tttctggtggctccatcagaagttactattggagttgggtccggcagtccccagggacgggactggaatggattgggtacaagttctacagtgggcccgccaaatataatccctctctcgagggtcgagtcacaatttctatagacacgtcgaagagtcaattcttcctgaggatgacgtctgtcaccactgcggacacggccgtctattattgtgcgagagaggacccctatttccgacattttgactggatcagcaatcgacccctggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaact 19462 JY8QFUQ01CTC3W No results 19463 JY8QFUQ01DTXTG unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19464 JY8QFUQ01AQEEF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19465 JY8QFUQ01BK5CM productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 850 90.34 187/207 nt 88.41 183/207 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.17.38.11] CARHPKSNVEGDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 8 nucleotides (from position 15 in the user submitted sequence), (cause frameshift) tctctggtgactccccacttctggagctggatccggcagccccccgggGAaagggcctggagtggattggttatgtctataacagtggGgaccaccaactacaaccCcctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccggcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttcccccag 19466 JY8QFUQ01A0XMS No results 19467 JY8QFUQ01BSZ2H No results 19468 JY8QFUQ01ABFGB productive (see comment) Homsap IGHV3-49*04 F 989 93.75 210/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcAaaagctgatgatgggacaacagaAatacgccgcgtctgtgaAaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19469 JY8QFUQ01A7C8P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); tctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggaTgggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaaggGgccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19470 JY8QFUQ01BBJ1V No results 19471 JY8QFUQ01AFBBD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagg 19472 JY8QFUQ01CIQUI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19473 JY8QFUQ01CMMBK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 615 92.96 132/142 nt 92.25 131/142 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 7 1 10 7.1.10 [1.X.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01CMMBK ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift) ctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19474 JY8QFUQ01A6IQL productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19475 JY8QFUQ01AM9OB productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19476 JY8QFUQ01C1SED productive (see comment) Homsap IGHV3-9*01 F 991 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKSGTYSSSSGHFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gcctctggattcaactttaataaGttatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19477 JY8QFUQ01AR4F8 productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1038 96.41 215/223 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 10 17 8.10.17 [1.17.38.11] CTRDNPPLRSLEWLPFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtgggtcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaaccggggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttaccctttgactcctggggccagggaaccctagtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19478 JY8QFUQ01BC1EW productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 103 62.9 39/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPTAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccaactgctcctaatcgattttactactactacggtttggacgtctggggcccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcgggtcttcccccctggcgccctgctccaggagcacctccgagancacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19479 JY8QFUQ01AWL52 productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccggggggggctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19480 JY8QFUQ01B4BLC No results 19481 JY8QFUQ01CRAFM unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.63 197/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD2-21*01 F 3 8 7 X 8.7.X [1.17.38.11] CTRELRLAAARDGVDI## out-of-frame + cttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggtacaatggtcaccgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctccgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19482 JY8QFUQ01CT4OG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 398 66.34 134/202 nt 65.84 133/202 nt 8 8 X 8.8.X [2.16.32.X] null - No rearrangement found Low V-REGION identity (66,34% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gcctctggattcccctttagcaactatgccatgacctgggtccgccaggctccagggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19483 JY8QFUQ01BUAPX productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattattgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19484 JY8QFUQ01AWY0L unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt 89.5 196/219 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNELGIL*WWG# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 78 of V-REGION: 'A' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); gcctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatActccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcgggatattgtagtggtgggggggggccagggagccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 19485 JY8QFUQ01C6ZTG productive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19486 JY8QFUQ01AKO1A unproductive (see comment) Homsap IGHV3-33*03 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-10*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARRNCGSGSHCYYYCDMDVW in-frame + stop codons cgtctggattcactttcaggaactatgacatgcactgggtccgccaggctccaggcaaggggctggagtgggtgacaatcatgtgatatgatggaaataataaacactatgcaggctccgtgaagggccgattcaccatctccagagacacctccaaaaccacactgtatctgtaaatgaatagcctgagggccgaggacacggctctgtttcactgtgcgaggagaaactgtggctcggggagtcactgttattactactgcgatatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 19487 JY8QFUQ01CC9YT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKQTIFDYYYYGLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctctggattcatgtttagtagctttcccatggcctgggtccgccaggGctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19488 JY8QFUQ01B9JIY productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19489 JY8QFUQ01CHDDF productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 899 89.29 200/224 nt 87.95 197/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 12 8.10.12 [1.17.38.11] CTITVRPDDYHDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); tctctggagtcactttcactaacgtgtggatgagttgggtccggcaggctccagggaaggggccggagtggGgttggccgtattaaAaagggagactgagggggggacaatagactacgctgcacccgtgacagcaagattcaccatgtcaaaagatgattcaaaaaaTcacactatatctgcaaatgaacaacctgaaaatggaggacacagccgtgtattactgtaccataacagtccgaccggatgattaccatgactactggggccagggaaccctggtgaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggctccagg 19490 JY8QFUQ01BZDK8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19491 JY8QFUQ01CIMAM productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 899 91.16 196/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - tttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19492 JY8QFUQ01A4JKL unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 41 90.0 9/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctccggatt 19493 JY8QFUQ01CNDUC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLAVILGGFGPYW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggaccgtactggggccagggaaacctggtcaccgtctcctcagcctccagccaaggccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19494 JY8QFUQ01B2VXM No results 19495 JY8QFUQ01DGTCA productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaaattatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19496 JY8QFUQ01DJL4L unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 126 54.81 74/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19497 JY8QFUQ01A4HCT No results 19498 JY8QFUQ01C0HKY unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGSYLYCFDY## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19499 JY8QFUQ01BGYLI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19500 JY8QFUQ01CKT96 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19501 JY8QFUQ01AGVK6 No results 19502 JY8QFUQ01DOO1T No results 19503 JY8QFUQ01BH2A1 productive Homsap IGHV1-2*02 F 921 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 1 8 8 12 8.8.12 [0.17.38.11] CATDVPAGQLWGYW in-frame - tggatacacattcaccgacaactatatgcactgggtgcggcaggcccctggacaggggcttgagtggatgggatggatcgaacctaacagtggagacacaaactatgcacaaaagtttcagggcagggtcaccatgacgagggacacgtccatcgccacagcctacatggagttgagcaggctgagagctgacgacacggccgtgtactactgtgcgaccgacgtccccgcagggcaactctggggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19504 JY8QFUQ01CJRYX unknown (see comment) Homsap IGHV3-7*01 F 932 92.2 201/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgtttggctgactactgggccagcgggaggtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19505 JY8QFUQ01C0KHV productive Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcaccaaggtcttccccgctgagcctctgcagcacccagccagatgggaaacgtggtcaatcgcctgcctggtccaggggcttcttccccc 19506 JY8QFUQ01DPA6S productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19507 JY8QFUQ01AELAP productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARASGRGDHGGDWFDPW in-frame + tctctggcgactccttcagtagtgctggttactattggagttggatccgccagcgcccagggaaaggcctggagtggattgggtccatctattacagtgggagtatctacttcaacccgtccctcaggagtcgaattaccatgtcagtggacacgtctaagaaccagttctccctgaagttgacctctgtgactgacgcggacacggccgtgtattactgtgcgagagcctctggtcgcggggatcacggtggggactggttcgacccctggagcctgggaaccctggtcaccgtctcctcagcatccccgacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaccgtggtcatcgcctgcctggtccagggcttgctt 19508 JY8QFUQ01CEHX4 productive (see comment) Homsap IGHV4-39*02 F (see comment) 683 80.0 172/215 nt 79.53 171/215 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 9 7 19 9.7.19 [X.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctctggattcacctttggcagctatatcatgagctgggtccgccagcCccccagggaagggactggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 19509 JY8QFUQ01ASEV1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 745 83.57 178/213 nt 83.1 177/213 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.37.11] CARGTRYNNGLDAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 92 of V-REGION: 2 nucleotides (from position 178 in the user submitted sequence), (cause frameshift) tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19510 JY8QFUQ01BLO8E unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1091 99.55 220/221 nt 99.1 219/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSAN#YW out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacagctgtgtattactgtgcgagaagtagaaccttctatggttcggccaacgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 19511 JY8QFUQ01AL0VQ No results 19512 JY8QFUQ01A3ULV unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 900 90.78 197/217 nt 89.4 194/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); atctggatacacctttatcacctactGggatcgcctgggtgcgccaaatgcccgggGAaaggccctggagttgatggggaGtcatctatcctggtgactctgagaccagatacagcccgtccttccaaggccacatcaccctctcagtcgacaagtccatcgataccgcctacctggagtggagcagcctgaaggcctcggacaccgccatgtacttctgtgcaagaagacaactggcccttgcctactgggggccagggaacccaggtcacccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19513 JY8QFUQ01ASLW8 productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 966 94.86 203/214 nt 94.39 202/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 3 8 8 17 8.8.17 [0.17.38.11] CASLPGDLTQIQDGVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggaggcaccttcgacagttatgttatcagctgggtgcgacaggGcccctggacaagggcttgagtggatgggcgggatcatccctatctttggttcggcaaagtatgcacagaagttccagggcagagtcaggattaccgcggacgaatccacgagcacggcctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgccagtcttcccggggatcttactcaaattcaagacggtgtttttgatatctggggccaggggacaatggtcagtgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcgcccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19514 JY8QFUQ01BRHNR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19515 JY8QFUQ01ACCN3 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 19516 JY8QFUQ01B88R2 productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19517 JY8QFUQ01BKFUT unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 688 91.98 149/162 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-16*01 F 1 X 7 X X.7.X [X.9.38.11] CARHPRPGTFDYLGG#WFDPW out-of-frame - gggaaggggctggagtgccttgggagcatcttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccttatccgttgacacttccaagaaccagttctccctgaagctgagctctgtggccgccgcagacacggctgtgtattactgtgcgagacatccccgcccgggaacttttgactacttagggggggttggttcgacccctggggccagggaattccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19518 JY8QFUQ01BCY6I productive (see comment) Homsap IGHV3-23*05 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [2.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 97 in the user submitted sequence), (do not cause frameshift) gcctctggatcaccctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19519 JY8QFUQ01AW5Y1 No results 19520 JY8QFUQ01AZS0F No results 19521 JY8QFUQ01ADD6P productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19522 JY8QFUQ01B3MKQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 1 8 8 18 8.8.18 [1.17.38.11] CAKDKNPVEMATISEILDYW in-frame - cctctggattcacctttaccaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgttgacacatactacgcagactccgtgaagggccggttcaccatctccagagacacttccaagaacacgctgtttctgcaaatgaccagcctgagagccgaggacacggccgtctattactgtgcgaaagataagaaccccgtagagatggctacaattagtgaaattctagactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19523 JY8QFUQ01BYGT0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'GG' (2 nucleotides at position 158 to 159 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccgagGGgggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatcctcgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19524 JY8QFUQ01DJT8W productive (see comment) Homsap IGHV3-11*04 F 997 96.71 206/213 nt 95.77 204/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 7 13 8.7.13 [1.16.37.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 65 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcagtgactactacatgatctggatccgccaggctccagggaaggggctgagtgggtttcatacattactagtcgtggtactatcatgtacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19525 JY8QFUQ01CYYIV No results 19526 JY8QFUQ01CTCP4 productive Homsap IGHV3-7*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARERSAAGVVFFDFW in-frame - Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaggggctggagtgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgcaaatgaacagcctgcgagtcgaggacacggctgtgtatttctgtgcgagagagagatcagcagctggagtcgtcttctttgacttttggggccagggagccccggtcaccgtctccagagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19527 JY8QFUQ01BDDG4 unknown (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 90.78 197/217 nt 7 8 X 7.8.X [1.17.38.X] null - No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctctggatttacttttaaaactattggatgacctgggttcgccaggctccagggGAagggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagaggggtcgtattggcattatgataccttcggcactatttggggggccccgggaggtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19528 JY8QFUQ01B1Q9S productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 805 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 7 7 9 7.7.9 [2.17.38.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 29 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) acgtctggatttaccttcagtaagttctgatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgnataatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19529 JY8QFUQ01CJ9NB productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19530 JY8QFUQ01A9QDL No results 19531 JY8QFUQ01A9DEW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaagggactacttccccgaaccggtgacggtgtcgtggaactc 19532 JY8QFUQ01AIZUH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19533 JY8QFUQ01AXYI6 No results 19534 JY8QFUQ01ARYZ1 No results 19535 JY8QFUQ01CAZ9T productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 719 97.37 148/152 nt 96.71 147/152 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 X 10 8.X.10 [1.14.27.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 53 of V-REGION: 66 nucleotides (from position 72 in the user submitted sequence), (do not cause frameshift) cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtggatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19536 JY8QFUQ01CVSA0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); tctctggCtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19537 JY8QFUQ01BXHJN No results 19538 JY8QFUQ01AYBIE productive Homsap IGHV4-61*02 F 830 85.97 190/221 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD4-11*01 ORF 2 10 7 15 10.7.15 [1.17.38.11] CARGFDYNKNRSDCDPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcaggagtggacttaattcttggacatggatccggcagcccgccgggaagggactggagtggattgggcgtgtccatttcaatggaaacaccaactacaacccctccctcaggagtcgggccaccatatcattggacacgtccaagaaccagttctccctgcagatgacctctgtgaccgccgcggattcggccgtctattattgcgcgagaggttttgactacaataaaaatcggtccgattgcgacccctggggccagggaaccctggtcaccgtctcctcagcctccgaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccaccagcggccctgggctgcctggtcaaggactcttccccgaacggtgacggtgtcgtggcactc 19539 JY8QFUQ01CRDRV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactca 19540 JY8QFUQ01CKSXC unproductive Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDGGVIVVVPMDYYGMDVW# out-of-frame + in FR3-IMGT at codon 86 of V-REGION: 'T' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); ctctggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcgagatggaactgagagtcattatgtggactctgtgaagggccgattcatcatctccagagacaactccaggaatTttactgtatctccaaatgaacagcctgagagtcgaagacacggctgtgtattattgtgtgagagatgggggtgttattgtagtagtgccaatggactattacggtatggacgtctgggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19541 JY8QFUQ01AN3OP unproductive (see comment) Homsap IGHV3-11*01 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDGPTLFIWKSW*F#FDQW out-of-frame + stop codons in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcagcttcagtgactactacatgagttgGggtccgccaggctccagGggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggccccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19542 JY8QFUQ01CFWWG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGVSGAFRWGFDYW in-frame - cctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19543 JY8QFUQ01A5NQZ productive Homsap IGHV3-66*02 F 913 91.67 198/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame + gcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19544 JY8QFUQ01A381T No results 19545 JY8QFUQ01B8JY3 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 965 93.21 206/221 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD3-10*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARLDAINWFDPW in-frame - tctctggtggcttcatcaccaataataatttctactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatcgattatagtgggagtaccgactacaacccgtccctcaggagtcgagtcaccatatccgtagacacgtccaagaaccagttcgccctgaggctgacttctgtgaccgccgcagacacggctatgtattactgtgcgagactcgacgcgataaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19546 JY8QFUQ01AWL6R No results 19547 JY8QFUQ01CRVVH productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctctggattcaccttcaatagatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaacactttgcagactccgtgaagggccgattcaccatctctagagacaattccaagaacactctgtatctgcaaatgaacagcctgagaattgaagacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccca 19548 JY8QFUQ01CNZKS unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 2 8 8 X 8.8.X [1.17.38.11] CANASPRITGN#YFYYYGMDVW out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactgggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19549 JY8QFUQ01B3B9N productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19550 JY8QFUQ01BQBH1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 886 90.28 195/216 nt 89.35 193/216 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 7 8 10 7.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 2 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) cctctggattcacctttgagatttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtGctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19551 JY8QFUQ01C26UN unproductive Homsap IGHV3-7*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDPYNGGGYGAFDI## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggGggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgctaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19552 JY8QFUQ01BZEA2 unproductive Homsap IGHV3-11*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGGRLQV#YYYGMDVW out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'AGTGGT' (6 nucleotides at position 21 to 26 in the user submitted sequence), (do not cause frameshift); tctctggtggctccatcaggAGTGGTagttactacatgagctggatccgccaggctccagggaaggggctggagtggatttcacacattagtagtagtggtagcatggtatacctggcagactctgtgaagggccgattcatcatctccagggacaacggcgagaactcactgtatcttcaaatgaacagcctgagagccgaagacacggccgtgtattactgtgcgagagatgggggacgactacaggtcgtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19553 JY8QFUQ01C9D90 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 110 53.24 74/139 nt 10 7 X 10.7.X [1.17.11.X] null - No rearrangement found stop codons tctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19554 JY8QFUQ01A96ZV unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CATSRGSANWYPFDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactgggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19555 JY8QFUQ01AXT5V unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 985 95.37 206/216 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGQRYCSNGVCSSFFDS## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19556 JY8QFUQ01BPQMT unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F 923 91.74 200/218 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRNNYYSDY## out-of-frame + cgtctggattcaacttcggaagttatggcatgcgctgggcccgccaggctccaggcaaggggctggagtgggtggcatttatttggtatgacggaagaaataaatattatgcagactccgttaagggccgattcaccatctccagagacaattccgagagcacactggatctgcaaatgaatagcctgagagccgaggacacggctgtctattactgtgcgagggataggaataattactactccgactactggggccaggggaaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19557 JY8QFUQ01C92PK productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctccctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19558 JY8QFUQ01CBMVH productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 791 85.58 184/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); tctctgggggCcaccatgagtagtttctactGggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttccctctgagcctctgcagcacccagccagatgggaacgtggtccatcgcctgcctggtccagggcttcttccccc 19559 JY8QFUQ01BTLFM No results 19560 JY8QFUQ01DEHI7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 390 75.18 106/141 nt 8 8 X 8.8.X [2.17.12.X] null - No rearrangement found Low V-REGION identity (75,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19561 JY8QFUQ01BHD18 productive Homsap IGHV3-33*05 F 976 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CARDVYNSRTNYFDQW in-frame - gtctggattcaccttcagtaactatggcatncactgggtccgccaggctccaggcaaggggctggagtgggtggcacttgtcttaaatgatggaagtaatgattactatgcagactccgtgaggggccgattcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatgtctacaattcccgaactaattactttgaccaatggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19562 JY8QFUQ01B7TTO productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcaccctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcca 19563 JY8QFUQ01AUI48 productive Homsap IGHV3-11*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtggctttcatacattagtggtagtggaactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaggaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgaggcgggtgtggggatatagttatggttccgtttcgtactactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19564 JY8QFUQ01ACN2Y productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 894 91.12 195/214 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [0.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + tggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19565 JY8QFUQ01B902J unproductive Homsap IGHV3-9*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDGSAIPVTGTYFEY## out-of-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtggatctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccaagggagccctggtcaccgtctcctcagcttccacaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19566 JY8QFUQ01C81S3 No results 19567 JY8QFUQ01CKMZ6 No results 19568 JY8QFUQ01BEFV1 productive Homsap IGHV3-7*01 F 1011 97.2 208/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19569 JY8QFUQ01BKHYH productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctaAtttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19570 JY8QFUQ01BBQBD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQ#NWFDPW out-of-frame - ctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19571 JY8QFUQ01A8GQZ No results 19572 JY8QFUQ01AE9OF productive (see comment) Homsap IGHV4-61*02 F (see comment) 783 84.79 184/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 101 in the user submitted sequence), (do not cause frameshift) ctctggtggccccatcagaggcggtggtttctactggacctggctccggcagTccgccgggaaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19573 JY8QFUQ01ADWU5 unproductive (see comment) Homsap IGHV4-4*07 F 844 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 8 7 X 8.7.X [1.17.37.11] CARDSG##FDYW out-of-frame - stop codons in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggaccccccactacaacccttccctnaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccattttttctgtgcgagagactccgggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19574 JY8QFUQ01CZ5RZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1053 98.62 214/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD5-24*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CARSQGFWYFDLW in-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagtagtagtggttacatatactacgcagactcagtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcgcagggattctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19575 JY8QFUQ01C3J0U unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.37.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 75 of V-REGION: 1 nucleotides (from position 128 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggcgattcaccatctccagagacaacgacagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19576 JY8QFUQ01AHEU2 No results 19577 JY8QFUQ01BHK93 productive (see comment) Homsap IGHV3-11*01 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.37.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 71 of V-REGION: 1 nucleotides (from position 121 in the user submitted sequence), (cause frameshift) cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaagggtctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggcccagggaaccctggtcacccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19578 JY8QFUQ01B1EY0 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19579 JY8QFUQ01A2DQ4 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 735 91.38 159/174 nt 90.23 157/174 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaagGgggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaaGgggccgattcaccatctccagagacaacgccaagaactcactgtatcttc 19580 JY8QFUQ01BMILN productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tccggaattcagatttcagtacttataacatgaaTttgggtccgccaggctcCcagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19581 JY8QFUQ01BIPS3 No results 19582 JY8QFUQ01DLD95 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPTFMI (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctactccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19583 JY8QFUQ01ASAYS unproductive Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.73 189/213 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDPYCSSTNCYPY## out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 19584 JY8QFUQ01DRBMX productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19585 JY8QFUQ01CNLWR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatCgggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19586 JY8QFUQ01CLGST productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19587 JY8QFUQ01CGUDC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 826 86.04 191/222 nt 85.59 190/222 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19588 JY8QFUQ01B8S8S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca 19589 JY8QFUQ01CV5MF unproductive (see comment) Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctgggggccgtggcacccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19590 JY8QFUQ01BNJLR No results 19591 JY8QFUQ01BIYVZ productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame + cctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctcccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcca 19592 JY8QFUQ01DKIFF unproductive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ5*02 F 101 67.35 33/49 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDILGLL# out-of-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttgggactactgggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19593 JY8QFUQ01A0GVR productive Homsap IGHV4-61*02 F 884 89.14 197/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame - tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19594 JY8QFUQ01DDQQ8 productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19595 JY8QFUQ01B20YK productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 88.94 193/217 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARVNKDSTDMW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtgactattggatgaggtggttccgccCagcctccaggaaagGGgggctggagtgggtggccagcataaAaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19596 JY8QFUQ01BUNBW No results 19597 JY8QFUQ01CIJBY productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19598 JY8QFUQ01ASB2P productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1047 99.07 212/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + ctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19599 JY8QFUQ01B38MC unproductive (see comment) Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcaacttcagaacctattagatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 19600 JY8QFUQ01BPG8K productive (see comment) Homsap IGHV4-61*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CTGGTT' (6 nucleotides at position 21 to 26 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); ctccggtggctccatcagtaCTGGTTattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19601 JY8QFUQ01AOQJN productive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame + ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19602 JY8QFUQ01CBZAJ unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 950 93.12 203/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgtccatagcatgaactgGggtccgccaggctccagGggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgaaagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19603 JY8QFUQ01A3YW3 No results 19604 JY8QFUQ01DWRYN productive (see comment) Homsap IGHV4-61*02 F (see comment) 700 79.73 177/222 nt 78.83 175/222 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-9*01 F 2 10 7 16 10.7.16 [2.17.38.11] CARERDRSIGGASELDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); gtctcttctgTgccccataagcagtggtggttactGattggaactggatccggcagcccgccgggaaggggctggagtggatcggacgtgttgacagtaatgggttcgtcaggtacaacagttccctcaagagtcgactttctatgtcggtggacatgtccaagagtcaggtctccctgaggttgaggtctgtgatcgccgcggacacggccgtatactattgtgcgcgagaacgcgataggtcgattggcggagcgtcagaacttgactcctggggccagggatctctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccaggagcc 19605 JY8QFUQ01DM608 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 121 96.15 25/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found ctccggggacagtgtctctaccaaca 19606 JY8QFUQ01A4NWM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKGDSGIRPIDYW in-frame + ctctggattcacctctagcgcctataccatgagttgggtccgccaggctccagggaaggggctggagtgcgtctcagctattagtggtggtggtactagcacatactacgcagactccgtgaagggccggttcaccatctccagagacacttccaagaacacactgtctctgcacctgaacagcctgagagtcgaggacacggccatatatttctgtgcgaaaggtgattctggtataagacctattgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctgcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgtggaact 19607 JY8QFUQ01B1L0F No results 19608 JY8QFUQ01CQJB9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19609 JY8QFUQ01B9RBS productive (see comment) Homsap IGHV3-11*01 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgtcgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19610 JY8QFUQ01BVGGJ productive Homsap IGHV3-48*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + ctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19611 JY8QFUQ01BIRCP unproductive (see comment) Homsap IGHV3-48*01 F 1000 95.43 209/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [2.17.38.11] CARERGKQLWR##DYW out-of-frame - stop codons in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtgggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19612 JY8QFUQ01BCOTN productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19613 JY8QFUQ01CB3Z0 unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKGTWIQ*LRP#DYW out-of-frame + stop codons Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaagggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19614 JY8QFUQ01DWXB5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGGRGLR#DYW out-of-frame - cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagagggggacgggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19615 JY8QFUQ01A6RWA No results 19616 JY8QFUQ01AVEEC productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19617 JY8QFUQ01CZHGO No results 19618 JY8QFUQ01CYO65 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKQKHSYGYYFDQW in-frame - cctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19619 JY8QFUQ01CK4FL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcgtctttggcgactatgcgatgagctgggtccggcaggctccagggagggggctggagtgggtctcaagtattagtggtagtggtgtcagcacatactacgtgggctccgtgaagggccgcttcaccatctccagagacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19620 JY8QFUQ01BYWI5 productive Homsap IGHV4-4*07 F 1061 99.53 214/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame + tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19621 JY8QFUQ01CK9QL No results 19622 JY8QFUQ01B0TQL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19623 JY8QFUQ01A8226 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 840 90.24 185/205 nt 89.27 183/205 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.16.38.11] CARHPKSNVEGDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 29 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift)in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift) tctctggtgactcccacttctggagctggatccggcagcccccgggaaagggctggagtggattggttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatgtctatagacacgtccaagaagcagatctctctgaggttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactcctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19624 JY8QFUQ01AGJTE No results 19625 JY8QFUQ01DQV12 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19626 JY8QFUQ01BVM72 productive Homsap IGHV3-11*01 F 1013 96.33 210/218 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD2-2*01 F 2 8 8 12 8.8.12 [1.17.38.11] CAVDCTSISCNGDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctgggttcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcggtagattgtactagtatcagctgcaacggagactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19627 JY8QFUQ01B6H3W unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.69 203/219 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [2.17.38.11] CARPFSGRWCFDL## out-of-frame - Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattCaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgatccaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctgggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19628 JY8QFUQ01C2YVS productive (see comment) Homsap IGHV4-59*03 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-9*01 F 2 8 7 18 8.7.18 [1.17.38.11] CAREDPYFDILHLGSAIDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tttctggtggctccatcagaagttactattggagttgggtccggcagtccccagggaCggggactggaatggattgggtacaagttctacagtgggcccgccaaatataatccctctctcgagggtcgagtcacaatttctatagacacgtcgaagagtcaattcttcctgaggatgacgtctgtcaccactgcggacacggccgtctattattgtgcgagagaggacccctatttcgacattttgcatctgggatcagcaatcgacccctggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaact 19629 JY8QFUQ01CCOGV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19630 JY8QFUQ01ACLBS unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaattacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19631 JY8QFUQ01BM2SX productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19632 JY8QFUQ01AY89G productive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 11 10.7.11 [1.17.38.11] CARSGWDNQFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggtgtcgccaccagtagtggcacttactactggagctggatccggcagtccgccgGgggcgggactagagtggattgggcgcatctataccggtcacaccaccatttacaacccctccctcaagggtcgagtcaccatgtcacttgacatgtccaagaaccagatctccctgaggctgacctctgtgaccgccgcagatacggccgtgtattactgtgcgcgaagtggctgggacaatcaatttgacttctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19633 JY8QFUQ01CLTY0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19634 JY8QFUQ01A06P5 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 716 81.19 177/218 nt 80.28 175/218 nt Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-3*02 F 1 8 8 X 8.8.X [1.17.38.11] CARIWDSWSGAF*CV# out-of-frame + stop codons Low V-REGION identity (81,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 15 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AG' (2 nucleotides at position 50 to 51 in the user submitted sequence), (cause frameshift); cctctggattccccCTtttagtgtgtactggatgtactgggtccgccaaAGtccccgggaaggggcccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtgaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagctttttgatgtgtgggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 19635 JY8QFUQ01CJSTZ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19636 JY8QFUQ01BWMFB productive Homsap IGHV3-7*01 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + gctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19637 JY8QFUQ01CAU7V productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 776 83.71 185/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARQSEPANNFNDPSRYFFDTW in-frame + Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcccgtgtctccatttccattaatgattactactggggctggatccgccagcccccaggaaagccgctggagtggattgggactgtccattcccttgggtacaattacaacaacccgtccctcaagagtcgactcaccatttccgcagacacgtccaggaatcagatctccctgaaactgacgtctgtgaccgccgcagacacggctgtctatttctgtgcgagacagagcgagcccgccaataacttcaatgacccaagtcgttatttctttgacacttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 19638 JY8QFUQ01CXS49 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19639 JY8QFUQ01CSKFG productive Homsap IGHV3-74*03 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + cctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19640 JY8QFUQ01C1ZFY unproductive Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-9*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPAGEGDPFF##YYSGLDVW out-of-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccgttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19641 JY8QFUQ01ANFV8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccaatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19642 JY8QFUQ01COC7Y unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 459 72.78 131/180 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found Low V-REGION identity (72,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaaggggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19643 JY8QFUQ01AF3MD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 797 85.32 186/218 nt 84.4 184/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDAGNTWPNYFDH## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); cctctggattcagctttttcaattatggGcatgaactgggtccgccaggctccagggaGgggggctggagtgggtcgcatttattagcggtgctggtgaaaatacttactacgcagactccgtgaagggccgattcgccatctccagagacgattcgagggacacactgtatctccaaatgagcagcctgagagccgaggactcggccctctattattgtgcgcgagatgcgggcaacacctggcccaactactttgaccactgggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19644 JY8QFUQ01CIVUV unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 248 75.0 69/92 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 2 X X X X.X.X [X.X.30.11] CAKGIVGSFYAS##WFHPW out-of-frame - Low V-REGION identity (75,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgtctttggcgacaattccaagaatgtgttgtatctgcaaatgaacggcctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtggggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19645 JY8QFUQ01B72VY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19646 JY8QFUQ01BG4TP productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 89.14 197/221 nt 88.69 196/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 1 10 7 10 10.7.10 [1.17.38.11] CARHYGSSLDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tcgctggtggctccatcagcagtagtagttatgagtgggtctggattcgccagGcccccagggaagggactggaatggattggaaaaatctatcatagtgggaacacctactacaatccgtccctcaggagtcgagtcatcatgtcaatagacacgcccaagaaccagttctccctgaggatgaactctgtgaccgccgcagacacggctgtttattactgtgcgagacactatggcagcagccttgactcctggggccagggcatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19647 JY8QFUQ01B3R2B unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGAT#YW out-of-frame - tctccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19648 JY8QFUQ01AQ0OL No results 19649 JY8QFUQ01DBODC unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 108 53.33 72/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcagtttcagagactatgccatgagttgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19650 JY8QFUQ01CK99N unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKKTL*FGDLF#YNFDYW out-of-frame - stop codons cctctgggattcacctttagccactatgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19651 JY8QFUQ01B9WJA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.95 202/215 nt 93.49 201/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 84 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagcccaaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19652 JY8QFUQ01C7ZLN unproductive (see comment) Homsap IGHV3-33*05 F (see comment) 761 83.49 182/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CVKGTWIQ*LRP#DYW out-of-frame + stop codons Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaGggggctggagtgggtggcgaccatttcatatgatattaataaaaaGatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaagggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19653 JY8QFUQ01AJEL4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 8 14 8.8.14 [1.17.38.11] CAKVGVMSARDRIDYW in-frame + cctctggattcacctttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtgggggtgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19654 JY8QFUQ01AHTOX productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 758 82.81 183/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); gtctctgtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggGagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19655 JY8QFUQ01BYFAI productive (see comment) Homsap IGHV3-48*01 F 820 86.3 189/219 nt 85.84 188/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctctggctttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19656 JY8QFUQ01B6W63 No results 19657 JY8QFUQ01B43HS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKEIAVSGEGALDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacAgtttagcaactatgccatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19658 JY8QFUQ01CQN0W unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - ctccgggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19659 JY8QFUQ01CHENJ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 595 82.66 143/173 nt 81.5 141/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found Low V-REGION identity (82,66% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); ctctggattcgagtttagtgcttattggatgacttgggtccgccaggctccaggaaaGggggctggagtGgggtggccagtattaagaaagatggacatgagaagaattatttggactccgtcaaggagcgattcaccatatccagagacaacgccagggactcggtgtctttgc 19660 JY8QFUQ01B93UC productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'GC' (2 nucleotides at position 12 to 13 in the user submitted sequence), (cause frameshift); ctctggattcaGCctttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19661 JY8QFUQ01B2E08 unproductive (see comment) Homsap IGHV3-7*01 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD2-21*02 F 2 8 8 X 8.8.X [1.17.37.11] CGRDEGRRLAE#DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 190 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagcccgaggacacgggtgtgtattattgtggcagagatgaagggcgccgacttgccgaatgattcctggggcctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19662 JY8QFUQ01C32SR productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPYNGGGYGAFDIW in-frame - cctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19663 JY8QFUQ01B00CV productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19664 JY8QFUQ01CLOHL unproductive Homsap IGHV3-30*10 F (see comment) 716 81.19 177/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD1-1*01 F 3 8 8 X 8.8.X [1.17.38.11] CSRGTTGTTDDSRLFQH# out-of-frame + Low V-REGION identity (81,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagcttcggcaattacgccatgcactgggtccgccaggctccaggcaagggcctagagtgggtggctgtcataaataaggctgggaagactaaacattatatagactccgtgaagggccgattcaacgtctccagagacaactccgagaaaacactctatttggagatgaataacgtgggagttgaggacacggctgtatattattgttcgagaggtaccacggggacgacagacgactcgaggttgttccaacactggggcagggcgccctggtcaccgtttcgtcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 19665 JY8QFUQ01A0Z64 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGSYLYCFDYW in-frame - ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtggtgatgatagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactgctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19666 JY8QFUQ01CWEOH productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame - ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19667 JY8QFUQ01ABTHU productive Homsap IGHV3-7*01 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDPYNGGGYGAFDIW in-frame + ctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgctaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagacccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19668 JY8QFUQ01CIF43 productive Homsap IGHV1-8*01 F 921 92.52 198/214 nt Homsap IGHJ3*01 F (see comment) 178 84.0 42/50 nt Homsap IGHD2-2*02 F 3 8 8 14 8.8.14 [0.17.38.11] CARLAAPLRAYALDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tggatacaccttcggcagttttgatatcaactgggtgcggcaggcccctggacaagggcttgagtggatggggtggatgaaccctcacagtggtaacacaggatatgcagagaacttccagggcagagtcaccatgaccagggacacctccataaacacagcctacatggagctgagcagcctgacatctgacgacacggccatatattactgtgcgagactagcagcacctttacgcgcctacgctttggacgtctggggccaagggaccgcggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19669 JY8QFUQ01CE2Z4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19670 JY8QFUQ01CQQDK productive (see comment) Homsap IGHV3-7*01 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); cctctggattcacctttagaagctatgccatgacctgggttcgccaggctccagggaaGggggctggaatgggtggGccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19671 JY8QFUQ01B6IHX productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMFYYGMDVW in-frame + catctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagctagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19672 JY8QFUQ01BOX74 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 869 88.99 194/218 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD6-25*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGRGQQREDAFDIW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcatcttcagtagttatagtttgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatatgagtagttcttacatctattatggagactcagtgaggggccgatttaccatctccagagacaacgccgagagttcactgtatctgcagatgagcagcctgagagccgaggacacggctttatattattgtgtgagaggcgggagggggcagcagcgagaagatgcttttgacatttggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19673 JY8QFUQ01C3MBF productive (see comment) Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 99.54 215/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19674 JY8QFUQ01CIXOC unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 851 88.07 192/218 nt Homsap IGHJ2*01 F 175 81.13 43/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CARQRGHSSSY#WSFDLW out-of-frame - catctggatacagctttacctccacatggatcggctgggtgcgccaggtgcccgggaaaggcctggagtggatgggtatcatctatcctggcaactctgaaaccaagtatagcccgtccttccaaggccgggtcgccatgtcagtcgacaagtccatcactaccgcctacctgatatggggcggcctgaaggcctcggacaccgccatgtattactgtgcgagacaacgaggccacagcagttcctacttggtccttcgatctctggggccgtggcacccaggtcatagtcaactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19675 JY8QFUQ01COB1R unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*02 F 2 10 7 X 10.7.X [1.17.38.11] CARLTDWWG##FDHW out-of-frame + stop codons tctctggtggctccatcagcggtacttctcattactggggctgggtccgccagcccccagggaaggggctggagtggattggcagtatctactctggtgggaccacctactacaacccgtccctcaagagtcgactcaccatgtccgtcgacacgtccaagaaccagatgtccctgcggctgagctctgtgaccgccgcagacacggctgtctattactgtgcgagactgacagactggtggggggcactttgatcactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19676 JY8QFUQ01AZ7JA No results 19677 JY8QFUQ01CU3VO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [1.16.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggaggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtatcgcctgcctcggtccagggcttcttcccccca 19678 JY8QFUQ01BEJCA productive Homsap IGHV3-48*02 F (see comment) 694 79.91 175/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD7-27*01 F 1 8 8 12 8.8.12 [2.17.38.11] CATDPNGDLDFDYW in-frame + Low V-REGION identity (79,91% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctccggattcatccccagtaactacggcatgaactgggtccgccagactccagggaaggggctggagtggattgcacacatcagtcacactggtgatggcacactttacgcagactctgtgaagggccgattcgccatctccagggacagttccaggacatcatattatttgcacataagtagcctgagagacgaggacacggctgcatattattgtgcgacagatccaaatggggacctagattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggttgtcgcatgcctggtccagggcttcttccccca 19679 JY8QFUQ01AKN9T productive (see comment) Homsap IGHV1-2*02 F 939 93.46 200/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19680 JY8QFUQ01ATQQZ unproductive Homsap IGHV1-18*01 F 867 89.72 192/214 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [0.17.38.11] CARGSGTSQNGMDV## out-of-frame - tggttacgcctttagcacctatgacatcagttgggtgcgacaggcccctggacaagggcttgagtggctggcctggatcagcacttatggtggtaacacaaattatgcacagctgctccagggcagagtcaccgtgaccagagacacatccacgagcacagccttcatggaactgaggagtctaagatctgacgacacggccgtgtattactgtgcgagagggagtgggacctcccaaaatggtatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19681 JY8QFUQ01CIISY No results 19682 JY8QFUQ01B7K2X unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 674 79.53 171/215 nt 78.14 168/215 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [0.17.38.11] CARERRPGVAIQMATTI#YGMDVW out-of-frame + Low V-REGION identity (79,53% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); cctctgatacaattagtcgttatggcatgcactgggtccgccaggctccaggcaaggggctggagtggctggcaattatttcatatgatggaaataggatatatgttggagactccgtgaagggccgcttcaccgtttccagagacaacgccgggaggactctgTtttctgcaaatTgaacagtctgagaggtgatgacaccgccacatattTtttgtgcgagagagcggcgtcccggggtggctatccaaatggctaccaccatttttacggcatggacgtctggggccaagggaccagggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaccagtgcgacggcgtgtcgtggaaact 19683 JY8QFUQ01A0OLH No results 19684 JY8QFUQ01DM7GD productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctGgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19685 JY8QFUQ01CY6SK productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 76 of V-REGION: 'T' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); tctggagttcaggctttagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaaatactatgtggactctgtgaagggccgaTttcaccgtctccagagacaacgccaagaactcactgttTtttgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgattagtagtgatttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19686 JY8QFUQ01C1RQB productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19687 JY8QFUQ01AC4M1 productive (see comment) Homsap IGHV3-30*12 F, or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 570 89.44 127/142 nt 88.73 126/142 nt Homsap IGHJ4*03 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 X 16 8.X.16 [1.4.34.11] CARWGYFGSGSYWDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 75 nucleotides (from position 41 in the user submitted sequence), (do not cause frameshift) gtctggattcagcctcagtagccatggcatacactggactcccatgaagggccgattcaccgtctccagagacaattccatgaacacactgtatctgcacatgaacagcctgagagtcgaggacacggctatgtattactgtgcgagatggggatattttggttcggggagttattgggatctcgactactggggcctggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19688 JY8QFUQ01CLJDU productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 795 84.3 188/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.17.38.11] CTTDSFHIAVHGVFDFW in-frame + Low V-REGION identity (84,30% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ttctgcattcatgttcaacaaagcctggatgaattgggtccgccaggctccaggaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 19689 JY8QFUQ01B78CT unknown (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 90.78 197/217 nt 7 8 X 7.8.X [1.17.38.X] null - No rearrangement found in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) cctctagattcacctttaatggtactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgagGgacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactgggggccagggaacccctggtcctcgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19690 JY8QFUQ01CG2OW unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [1.17.38.11] CARLCGNDCRND#FDIW out-of-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgttttgatatctggggccaagggacattggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19691 JY8QFUQ01BSB9L productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt 86.64 188/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 140 to 140 in the user submitted sequence), (cause frameshift); ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatatacgcggactccgtaAaagggccggttcaccatTttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19692 JY8QFUQ01AAUWG productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19693 JY8QFUQ01BIGM6 productive Homsap IGHV1-2*02 F 827 87.44 188/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + ctggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19694 JY8QFUQ01AR363 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 111 56.19 59/105 nt 8 8 X 8.8.X [1.17.X.X] null - No rearrangement found stop codons cctctggattcaccttcagtcgttatagcatgaactgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19695 JY8QFUQ01BYPOG productive (see comment) Homsap IGHV4-4*07 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19696 JY8QFUQ01BP3GN productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 979 95.77 204/213 nt 93.9 200/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 3 8 7 11 8.7.11 [1.16.38.11] CASLHPTEERDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 46 of V-REGION: 2 nucleotides (from position 53 in the user submitted sequence), (cause frameshift) tctatggtgagtcctTtcagtggCatactactggagctggatccgccagcccccggaaggggctggagtggattggagaaatcCaatcatagtggaagcaccacctacaacccgtccctcaagagtcgagtcaccatatcaatagacacgtccaacaaccagttctccctgaggctgagctctgtgaccgccgcggacacggctttttattactgtgcgagccttcaccccacagaggaaagggactactggggccagggaactctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19697 JY8QFUQ01BBOTL productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1000 93.42 213/228 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [2.17.38.11] CARGSSRGGRSDVNYYELDFW in-frame + tctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtcctcatcgagaggcctcgagtggctgggaaggacatactacaggtccaagtggtattatgactatgcagtgtctgtccaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaattctgtgactcccgaggacacggctgtgtattactgtgcaagagggtccagccgcggggggagatctgatgtgaactactatgagctggacttctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19698 JY8QFUQ01C7FF1 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD4-23*01 ORF 2 9 7 10 9.7.10 [1.17.38.11] CASHGGKYFPQW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcCccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 19699 JY8QFUQ01A61VS productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 880 88.74 197/222 nt 86.49 192/222 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [2.17.38.11] CARQLSGDYASFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'G' (1 nucleotides at position 172 to 172 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'T' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); gtctctggtgcctccatcaccCagtggtactttttactggggCctggatccgccagcccccagggaAaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagGttttccctgacactgacctctgtgTaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19700 JY8QFUQ01DB7BX productive (see comment) Homsap IGHV3-33*05 F (see comment) 767 83.26 184/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cagcgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtAgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 19701 JY8QFUQ01CKQX2 No results 19702 JY8QFUQ01ASJWX unknown (see comment) Homsap IGHV4-61*04 F (see comment) 311 60.37 131/217 nt 59.91 130/217 nt 10 7 X 10.7.X [1.17.37.X] null - No rearrangement found Low V-REGION identity (60,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtgGgaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaaccccctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19703 JY8QFUQ01AUMIA No results 19704 JY8QFUQ01CZTM0 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19705 JY8QFUQ01CPO7R productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gcctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19706 JY8QFUQ01B4A7K productive (see comment) Homsap IGHV4-39*02 F (see comment) 772 83.33 185/222 nt 82.88 184/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [2.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gtctccggtgtctccattagtagtgataCtttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19707 JY8QFUQ01BGKHN unknown (see comment) Homsap IGHV4-61*02 F (see comment) 522 70.97 154/217 nt 10 7 X 10.7.X [1.17.37.X] null + No rearrangement found Low V-REGION identity (70,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19708 JY8QFUQ01A88CH No results 19709 JY8QFUQ01CE67S productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag 19710 JY8QFUQ01DDASA No results 19711 JY8QFUQ01BOQD6 productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagCttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19712 JY8QFUQ01BKXOR unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 204 60.87 84/138 nt 8 7 X 8.7.X [2.17.12.X] null - No rearrangement found stop codons The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BKXOR ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (60,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctcgacaggcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19713 JY8QFUQ01BLQL8 No results 19714 JY8QFUQ01DS502 productive Homsap IGHV2-5*05 F, or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 1058 92.65 227/245 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 10 7 12 10.7.12 [9.17.38.11] CGHMDQWLATFDFW in-frame - agaccctcacgctgacctgcaccttctctgggttctcactcagcaccagtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattgggatggtgataagcgctatgacccatctctgaggaatagactcaccatcaccaagaaaacttccaaaaatcaggtggtccttaccatgacttccctggaccctgtggacacagccacatatttctgtggacacatggaccagtggctggcgacttttgacttctggggccagggtatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19715 JY8QFUQ01CLACL unproductive Homsap IGHV3-7*01 F 837 87.56 190/217 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CGRDERGADLPNDS## out-of-frame + ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcagatgaacagcctgagccccgaggacacgggtgtgtattattgtggcagagatgaaaggggcgccgacttgccgaatgattcctggggccctgggaaccctggtcaccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19716 JY8QFUQ01BBZX9 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19717 JY8QFUQ01AULAR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame + ctctggattcaactttggcatctataccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19718 JY8QFUQ01ATM3Z unproductive (see comment) Homsap IGHV3-7*03 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-8*02 F 3 8 8 12 8.8.12 [2.17.38.11] CVDIRLGDWFFDLW in-frame - stop codons in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtgactattggatgagctgggtccgccaggctccagggaaggggctagagtgggtggccaacataaaataGagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacggcctcagagtcgaggatacggccgtctattactgtgtcgacataagactgggtgattggttcttcgatctctggggccgtggcaccctggtaactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19719 JY8QFUQ01BIKKF productive (see comment) Homsap IGHV4-4*07 F 863 89.3 192/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 1 8 7 9 8.7.9 [1.17.38.11] CARDSGDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'T' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctctggtgtctccattacgacttactattggagttggattcggcagcccgccggaaagggactggagtggattgggcgtgtccaaaccagtgggagCcccccactacaacccctTccctcaagagtcgagtcaccatgctagtagacacgtccaggaaccaggtctccctgaagctgacctctgtgaccgccgcggacacggccatttttttctgtgcgagagactccggggactttgactactggggcccgggaattgtggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19720 JY8QFUQ01DQIKZ productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19721 JY8QFUQ01C519L unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-25*01 F 1 8 7 X 8.7.X [2.17.38.11] CGKDVRGGLSLEEATKLPPP*LL# out-of-frame - stop codons in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) gcctctcgggttctccttcagtgcctatgccatgacctgggtccgccaGggctccagggagggggccggagtgggtctcgtctattagcagtggtagtttaacacattacgcagactccgtgaGggggccgattcaccgtctccagagacaattccaagagcactctgtttctgcaaatggacagcctgagaaccgaggacacggccgtatattactgtgggaaagatgttagaggcggtctcagtctggaagaggctactaaactaccccccccctgactactgggggccagggaaccctggtcaccgtctcctcagcctccatcaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19722 JY8QFUQ01ANX1P unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.37.11] CARGGIYL*QPV# out-of-frame + stop codons The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01ANX1P ; 8 AA in Homsap_IGHV4-59*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 184 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagcggcagtaccaactactggacctggatccggcagcccccaggaaagggactggaattcattgggtatatctataacagtggcaacaccaactacaacccctccctcaagagccgagtctccatttctttggacaggtccaagaaccagttctccctgaggctgaccccgtgaccgctgcggacacggccatgtattactgtgcgagggggggcatatacctatgacagcccgtgggggccagggaacccgggtcaccgtctcctcggcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 19723 JY8QFUQ01CVDNM unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19724 JY8QFUQ01BZB9T productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD6-19*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARTEYVSGWYIGGFDPW in-frame + ctatggtgggtcactcagttcttatttctggagctggatccgccagtccccagagaaaggactggagtggattggggaaatcaatcagagtggaaccaccaactacaacccgtctctcaggagtcgagtcaccatagcaatagacacgtccaagaaccagttctccctgaaggtgacctctgtgtccgccgcggacacggctgtctattactgtgcgaggaccgagtatgtcagtggctggtacatcggggggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19725 JY8QFUQ01BFI4C productive (see comment) Homsap IGHV3-7*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [2.17.37.11] CARTSSREITDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift) gcctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19726 JY8QFUQ01B5Z84 productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 19727 JY8QFUQ01A2OMT productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctcccaccgaacgggcccatcggtcttccccctggcaccctcctccaagagcaccctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19728 JY8QFUQ01A4PI2 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 819 86.18 187/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19729 JY8QFUQ01C9VEQ No results 19730 JY8QFUQ01BZZZ2 productive Homsap IGHV3-49*02 F, or Homsap IGHV3-49*03 F or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F (see comment) 457 83.33 110/132 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD3-3*01 F 2 X 6 16 X.6.16 [X.X.38.11] CARDRDYHDSWPDSFDVW in-frame + Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcttctggattcaccttagaatacgccgcgtctgtgaaaggaagattcaccatctcaagagatgactccgagggcatcgcccacctagagatgaacagtctcaacaccgaggacacagccgtgtattattgtgctagagaccgcgattatcacgatagttggcccgattcttttgatgtctggggcccagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccga 19731 JY8QFUQ01DHZ1T unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 88 51.91 68/131 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacaacacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19732 JY8QFUQ01CANC3 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 892 89.95 197/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARDPSGSGWAFESW in-frame - gcgtctggattccctttcagtagagatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatggtatggtatgatggaagtaatacacaccatgcagattccgtgaagggccgattcatcatttccagagacaattccaagaataaagtgtatctgcaaatgaacagtctgagagacgaggacacggctgtctattattgtgcgagagatccgagcggcagtggctgggcctttgagtcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19733 JY8QFUQ01CT2F5 unproductive Homsap IGHV3-30*16 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDELPWDTIEYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'T' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ctctggattcaacttcaggacctattctatgcactggctccgccaggcTcccaggcaagggactagagtgggtatcagttaTtttcatatgatggaactaagaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctacaaatggacagcctgagacctgaggacacggctgtgtattactgtgcgagagatgaactgccttgggatacaatagagtattactttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagctctgcagcacccagccagatgggaacgtggtcatcacctgcctggtccagggcttcttccc 19734 JY8QFUQ01DL8K2 productive (see comment) Homsap IGHV3-9*01 F 910 90.87 199/219 nt 90.41 198/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 7 8 22 7.8.22 [2.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift) agcctctggattcactttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagccctccaccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19735 JY8QFUQ01CDPNG unproductive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19736 JY8QFUQ01B1L81 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [1.17.38.11] CAKNNNDFGDYDWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagCcccccagggaagggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19737 JY8QFUQ01A3A5F productive Homsap IGHV1-8*01 F 840 87.85 188/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgtccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19738 JY8QFUQ01CHB9V unproductive (see comment) Homsap IGHV1-18*01 F 943 93.9 200/213 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt 8 8 8 8.8.8 [X.17.38.11] CARGDYFDH* in-frame - stop codons ggttacacctttaccagctatggtctcagctgggtgcgacaggcccctggccaagggcttgagtggatgggatggatcttcgtttttaacggtaacacaaaatatgcacagcacctccagggcagagtcaccatgaccacagacacatccacggacacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagaggtgactactttgaccactagggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19739 JY8QFUQ01B3MM5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19740 JY8QFUQ01C3SNK productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - tctctggtggctccatcgatagttactactggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19741 JY8QFUQ01CAJS1 productive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt 94.44 204/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift); tctggtttcaccttcaggagctctggcaGtgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19742 JY8QFUQ01CGUEK No results 19743 JY8QFUQ01CI0GE unknown (see comment) Homsap IGHV3-7*02 F 108 59.26 48/81 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19744 JY8QFUQ01A9PH6 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1018 96.35 211/219 nt 95.89 210/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDLYDSSGSFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGccttcagcagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtaggagtagtaccaaaaactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgcgagagatttgtatgatagtagtggttcttttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttctccgaaccggtgacggtgtcgtggaactcag 19745 JY8QFUQ01CSXT8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDPFIAATGRP#YFEYW out-of-frame - Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggactcaacattggcaactatgacatgacctgggtccgccaggctcctgggaaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaaacacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgccctggtactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19746 JY8QFUQ01CB3LZ productive (see comment) Homsap IGHV3-74*03 F 847 87.67 192/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); gcctctggattcacgtttcCacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19747 JY8QFUQ01AMBU7 productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaAaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 19748 JY8QFUQ01C1BLG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19749 JY8QFUQ01CI2JP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 48 to 49 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagGCtccgagggaaggggctggttgggtctcacgtgttaatggtggatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagtcccaaggtcttcccgctgagcctcgacagccaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19750 JY8QFUQ01BX9XW unproductive Homsap IGHV1-2*02 F 921 92.52 198/214 nt 91.12 195/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [0.17.38.11] CVRDEFRKKWEPDSDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); tggatacacgttcaTcagcctactatatgcCagtgggtgcgacaggGcccctggacaagggcttgagtggatgggatggatcaaccctgacagtggtggcacagagtatgcagagaagtttcagggcagggtcaccatgaccagggacacgtccgtcagtacagtctacatggagctgaagaacctgagatctgacgacacggccgtctattactgtgtgagagatgaatttcgaaagaagtgggagcccgactctgactactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19751 JY8QFUQ01B4DWA productive (see comment) Homsap IGHV1-69*01 F, or Homsap IGHV1-69*11 F or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 854 88.84 191/215 nt 87.91 189/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD5-18*01 F 1 8 8 17 8.8.17 [0.17.38.11] CASDREDTAMITAESFNIW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); ctggaggcaccttcagtagacatgctatcaactgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcaaccccaCtccttcatacaAccaaaatatgcacagaggttccagggcagagtcacatttaccgcggacgaatccacggccacagtctacatgcaactgagcagcctgggatctgaagacacggccgtctattattgtgcgagcgatcgggaagatacagctatgattaccgcggagagttttaatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 19752 JY8QFUQ01BP0GT unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNAAGRLWYYYGMDVL## out-of-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaacgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19753 JY8QFUQ01BWDBU unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDTLEVVSNMDDAFDL## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggcccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19754 JY8QFUQ01B6LPS productive (see comment) Homsap IGHV3-48*01 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19755 JY8QFUQ01CU62M productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.16.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 51 of V-REGION: 2 nucleotides (from position 66 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggttggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 19756 JY8QFUQ01AW4XS unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 406 89.11 90/101 nt 8 7 X 8.7.X [1.17.X.X] null - No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagggtgttgaca 19757 JY8QFUQ01DIUSB productive Homsap IGHV3-21*04 F 995 95.41 208/218 nt Homsap IGHJ5*01 F (see comment) 111 68.63 35/51 nt Homsap IGHD6-13*01 F 1 8 8 11 8.8.11 [1.17.38.11] CAERPFRIRLDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccattagttttagtagtgattacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtgtattactgtgcggagcgtccgttcagaatcaggttggacgtctggggccaaggggaccacggtcacgtctcctcagcatccccggaccagcccctaaggtcttcccgctgagctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19758 JY8QFUQ01AL3F7 No results 19759 JY8QFUQ01CHPXI No results 19760 JY8QFUQ01B0BDK productive Homsap IGHV3-11*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-7*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARGKGKGGTTYYGMDVW in-frame - cctctggattcactttcagtgactactacatgaattgggtccgccaggctccagggaagggcctggagtggctttcatacattactgcaagtggtgccatcatacactatgcagactctgtgaagggccgattcatcatctccagggacaacgccaagaactcactgtctctgcagatgaacagcctgagagccgacgacacggccgtctattattgtgctcgggggaagggcaagggtggaactacctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19761 JY8QFUQ01A2HPP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19762 JY8QFUQ01BHZC2 No results 19763 JY8QFUQ01C3WSP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19764 JY8QFUQ01DFGZR productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION cgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19765 JY8QFUQ01C5JVO productive Homsap IGHV4-61*02 F 1037 96.83 214/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARGPKYYYDSSGFEDLW in-frame - tctctggtggctccatcagcagtggtcgttactactggagctggatccggcagcccgccgggaagggactggaatggattgggcgtatttataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagctctccctgaagttgagttctgtgaccgccgcagacacggccgtatattactgtgcgagaggtcccaagtattactatgatagcagtggtttcgaagacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19766 JY8QFUQ01DV1WY unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 181 97.37 37/38 nt 8 X X 8.X.X [1.3.X.X] null - No rearrangement found ctctggattcatcttcagtagctactggatgcactggg 19767 JY8QFUQ01BPAPP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagctcgacagcacccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19768 JY8QFUQ01AYRAD productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19769 JY8QFUQ01AT1U6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1023 94.32 216/229 nt Homsap IGHJ2*01 F 103 66.04 35/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [5.17.38.11] CAKVVWSLWYFDLW in-frame - ctcctgtgcagcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcacccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19770 JY8QFUQ01B3W6V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctntggattccCcctttagcaactatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19771 JY8QFUQ01AD3NZ unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGYLLVLF*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggtacttacttgtactattttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19772 JY8QFUQ01BCT61 productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 668 79.72 169/212 nt 79.25 168/212 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [0.17.38.11] CVRDAETTVSGVAGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (79,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) ctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19773 JY8QFUQ01BHVEV productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 748 82.65 181/219 nt 81.28 178/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-21*01 F 3 8 8 17 8.8.17 [2.17.38.11] CAMRLFVVVLSATLILTTG in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'AT' (2 nucleotides at position 215 to 216 in the user submitted sequence), (cause frameshift); gcctctgggttcacattcagtaactactGggatccactgggtccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaatgccaagaacacagtgtatctgGgaaatgactagtctgagagtcgacgacacggctgtctaATtttttgtgcaatgcgactttttgtggtggtcctgagtgctacccttatcttgacaactgggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19774 JY8QFUQ01ANO71 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); agcctctggattcgccttcagttggtattggatgcactgggtccgccaagctccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19775 JY8QFUQ01C98IO productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 906 92.42 195/211 nt 91.0 192/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 7 8 13 7.8.13 [X.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 28 in the user submitted sequence), (cause frameshift) ggatcacctttggttattGatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19776 JY8QFUQ01CE5JH productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame - Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19777 JY8QFUQ01A004N productive (see comment) Homsap IGHV4-39*02 F 920 90.95 201/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagtaggagtgcctactactggggctggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtGgggaccacatactccaatccgtcCcctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19778 JY8QFUQ01CLY7N productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 8 8 8.8.8 [1.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19779 JY8QFUQ01CGSBA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19780 JY8QFUQ01B3134 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 833 87.16 190/218 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 175 75.81 47/62 nt Homsap IGHD4-17*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARLRSFGDYPLDVW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcaatctattcgggatgctctgggtccgccaacttccggggaagggactggtgtgggtctcacatattaatactgatggtactaaaatagatcacgcggactccgtgaagggccgattcaccacctccagagacaacgccaagaacaccctctatctgcaaatgaacagtctgagagccgaggacacggccgtatatttctgtgcgagactgcggtctttcggcgactaccccttagacgtctggggccaggggaccacggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19781 JY8QFUQ01BNPXL productive (see comment) Homsap IGHV3-23*03 F (see comment) 531 71.89 156/217 nt 70.97 154/217 nt Homsap IGHJ2*01 F 166 79.25 42/53 nt Homsap IGHD3-3*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARVRNSNWYFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (71,89% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'TA' (2 nucleotides at position 121 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctgaagacatgtttaagagtttcggattgacgtgggtccgtcaggctccagggaaggggctggagtgggtcgcaggaataaacaattacaatggtgcaactttctatgctggccccgtTAaaagggccgcttcaccgtctctcgagataaagaaaagaccacttTtttatctacaaatggacaacgtgagggtcgacgacacgggcgtttatttctgtgcgagagtcaggaatagtaattggtacttcgaccactggggccgcggcgcactagtcacagtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19782 JY8QFUQ01CMUST unproductive (see comment) Homsap IGHV4-61*01 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*03 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARDGNERLLLF*NL in-frame + stop codons Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatgagaggttattactcttttgaaacctgggccgagggacattggtcaccgtctcctcagctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtcgtcgtggaactc 19783 JY8QFUQ01CCV7N productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt 83.56 183/219 nt Homsap IGHJ3*02 F (see comment) 142 76.0 38/50 nt Homsap IGHD1-1*01 F 3 8 8 17 8.8.17 [2.16.38.11] CAKDIWAREWNDMAAFQMW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 52 in the user submitted sequence), (cause frameshift) cgcccccggaatcacttttcccagctatgtcatgagttgggtccgccaggcccagggaaggggctggagtgggtcgcaagcattagtgccaggggcgacagttcatactacgcagactccgtgaagggccgattcaccatctccagggacaatcccaggaccacattgtatctggaaatgaacagtctgagagtcgaagacacggccacatattattgtgcgaaagatatctgggcgcgagagtggaacgacatggcggcttttcagatgtggggccaggggacacttgtcattgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19784 JY8QFUQ01CQXRE unproductive Homsap IGHV3-11*01 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRRDYGDYGDGFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtGgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19785 JY8QFUQ01CSDB8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 491 69.27 151/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] VHT#AFW out-of-frame + Low V-REGION identity (69,27% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgaggacaactttggtgaacacgccatgggatggatccgccagtctccgggggggattcttcagtgggtcgctgcgatcagtggtgacggactgacggcgtttcacgcagacttcgtggagggtcgattcagcatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctattttgtgcacacactgccttctggggccggggatcccgggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19786 JY8QFUQ01CDJAN productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactatcacatgtactgggtccgccaggCctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19787 JY8QFUQ01B6PJ2 productive Homsap IGHV3-7*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - tctggattcacctttgagacttattggttgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagacatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19788 JY8QFUQ01ASVTH unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 112 67.92 36/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgCaggggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctagtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19789 JY8QFUQ01DNAQY unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 123 68.42 39/57 nt 8 X X 8.X.X [1.9.X.X] null - No rearrangement found ctccggattcacctttagtagttactggatgcactgggtccagggcttcttccccca 19790 JY8QFUQ01COTDH productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame - tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19791 JY8QFUQ01AJWSY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYFYYFDYW in-frame + cctctggattcacctttagccactatgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagtggtagtgatggtagcacgtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagaagtatcactatggttcggggacttacttctactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 19792 JY8QFUQ01DAHIV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 720 81.57 177/217 nt 81.11 176/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 83 to 85 in the user submitted sequence), (do not cause frameshift); ctcagggttcgtttttgagaaatacgccatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19793 JY8QFUQ01C2LQE No results 19794 JY8QFUQ01B112M productive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19795 JY8QFUQ01CEI8V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19796 JY8QFUQ01ACMBD productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggGggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19797 JY8QFUQ01C7TDI productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaAaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19798 JY8QFUQ01AYYP6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-14*01 ORF 3 8 8 19 8.8.19 [1.16.38.11] CARIIPYDPRTDYYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) cctctggattcagcttcagtaattatatcatgacttgggtccgccaggccccaggaaggggctggagtgggtctcatctattagtggaagtagtagtaacatattctacgcagactcaatgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaataatcccgtatgacccgaggaccgactattattactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 19799 JY8QFUQ01BYPSH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacatactGggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19800 JY8QFUQ01DLCKG No results 19801 JY8QFUQ01CDKKA productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggatcacctttggttattgatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19802 JY8QFUQ01BGWV8 No results 19803 JY8QFUQ01C0M54 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 1 10 7 X 10.7.X [1.17.38.11] CARRWARQRLVM##YFDYW out-of-frame + stop codons tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatgggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc 19804 JY8QFUQ01C2GP3 No results 19805 JY8QFUQ01BSGCZ No results 19806 JY8QFUQ01B4YC4 productive Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARDSVPRASEAAYHFDYW in-frame + cctctggattctccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19807 JY8QFUQ01B41ZK No results 19808 JY8QFUQ01DGIH1 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons ctgattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19809 JY8QFUQ01A2MDY No results 19810 JY8QFUQ01AH7FL unproductive Homsap IGHV1-2*02 F 795 85.98 184/214 nt 85.51 183/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [0.17.38.11] CARDWGGTYAPLDN## out-of-frame + in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); tggatacaTttttcaccggctactatatacattgggtgcgacaggccgctggacaagggcttgagtggatgggatacatcgacccttacagaggtgacacaaggtttgcagagaaatttcagggcagggtcaccttgaccagagacacgtccatcagtacagcctacatggaaatgaccggcctgacgtctgaggacacggccatcttttactgtgcgagagattggggtggcacgtacgcaccgcttgacaactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19811 JY8QFUQ01AE2X1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 19812 JY8QFUQ01AC1Q0 productive Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-25*01 F 1 8 8 10 8.8.10 [1.17.38.11] CTKLYRSYYEYW in-frame + cctctggattcagttttagtgactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaatatgaatcaagatggaagtgagaaaaactatgtggactctgtgaagggtcgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatgtattattgtacgaaattgtatcggagctactacgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 19813 JY8QFUQ01B0RU8 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 19814 JY8QFUQ01AD9KX unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 919 91.32 200/219 nt 90.41 198/219 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKDMGSGRYLEALDHW# out-of-frame - in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); gggtctgacctcatatttactaaatatggcGttccactgggtccgccaggctccaggcaaggggctggagtgggTtggcacttatttggtttgatggaagtaataaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtatttctgtgcgaaggatatgggttcgggaagatacttagaagctcttgaccactgggggccccgggaatccaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19815 JY8QFUQ01C1SS7 unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F (see comment) 319 64.25 115/179 nt 8 8 X 8.8.X [1.17.25.X] null - No rearrangement found Low V-REGION identity (64,25% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcttcttcagcagttttggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggcagtcacatcatatgatggaggtaataaattttatggagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19816 JY8QFUQ01DHU43 unproductive Homsap IGHV3-9*01 F (see comment) 755 83.72 180/215 nt 82.79 178/215 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.16.38.11] CGRIAKPGLGALDL## out-of-frame - Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 30 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) cgttggattcacttttaatggaacaggcagcagtggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctgggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19817 JY8QFUQ01ALMRY productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F (see comment) 69 60.42 29/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattaGtgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaacccctggtcaccgtctcctcagccctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19818 JY8QFUQ01A8G4A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gcctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19819 JY8QFUQ01AELU5 productive Homsap IGHV4-61*02 F 791 99.38 160/161 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 X 7 15 X.7.15 [X.8.38.11] CARGYCSNAVCYQIMNW in-frame - ggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagccaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19820 JY8QFUQ01CG5WF unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 994 95.83 207/216 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCFNS## out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19821 JY8QFUQ01AE75W unproductive (see comment) Homsap IGHV3-48*02 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD2-15*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARPAGGG*PFFPLLLRFWTSG in-frame - stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 104 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattacTtgtgcgagacccgcggggggagggtgacccttttttccactactactccggttttggacgtctgggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19822 JY8QFUQ01B3IG6 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaAaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19823 JY8QFUQ01COSA2 No results 19824 JY8QFUQ01A8NCY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 788 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 8 13 8.8.13 [1.17.38.11] CVRGVRDGTGIIDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cccatggattcctcttcagtggccactggatgcactgggtccgccaagctccagacaaggGggctggcgtgggtctcacgtcttaacccggacgggagttttacgaactatccggactccatgaggggccgattcgccatctccagagacaacgccaagaacacagtgtatctgcaaattaacaatctgagacccgatgacacggccgtctattactgcgtaagaggcgtaagagacggaactggaatcatcgactactggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19825 JY8QFUQ01A9POG productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1041 99.53 210/211 nt 97.63 206/211 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.16.38.11] CASANYDYVWGSYRYDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'GA' (2 nucleotides at position 152 to 153 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 31 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 42 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagtagttactactgagctggatccgcagcccccagggaagggactggagtgattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagGAacccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19826 JY8QFUQ01AE4GX productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 899 89.29 200/224 nt 88.84 199/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 2 8 10 12 8.10.12 [1.17.38.11] CTITVRPDDYHDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggagtcactttcactaacgtgtggatgagttgggtccggcaggctccagggaaggGggccggagtgggttggccgtattaaaagggagactgagggggggacaatagactacgctgcacccgtgacagcaagattcaccatgtcaaaagatgattcaaaaaacacactatatctgcaaatgaacaacctgaaaatggaggacacagccgtgtattactgtaccataacagtccgaccggatgattaccatgactactggggccagggaaccctggtgaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19827 JY8QFUQ01DGRL0 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 367 67.61 119/176 nt 8 8 X 8.8.X [1.17.24.X] null - No rearrangement found stop codons Low V-REGION identity (67,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19828 JY8QFUQ01CIPSL productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19829 JY8QFUQ01CRQ1F productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - ctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattattgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19830 JY8QFUQ01BOUUI productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*02 F or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*08 F 853 90.73 186/205 nt 89.76 184/205 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 5 7 12 5.7.12 [1.16.38.11] CARHPKSNVEGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 9 nucleotides (from position 14 in the user submitted sequence), (do not cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) tctctggtgactctcacttctggagctggatccggcagcccccagggaagggcccggantggattgttatgtctataacagtgggaccaccaactacaacccctccctcaggagtcgagtcaccatttctatcgacacgtccaagaagcagatctccctgaagttgaactctgtgaccgctgcggacacggccgtgtattactgtgcgagacacccgaagtccaacgtagagggtgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 19831 JY8QFUQ01BS2G8 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19832 JY8QFUQ01APP4N unproductive Homsap IGHV3-9*01 F 845 88.37 190/215 nt 87.91 189/215 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [0.17.38.11] CARTYGDHDGMDV## out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); ctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatcCtttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 19833 JY8QFUQ01AO51H productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARLPNTIDSW in-frame + Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19834 JY8QFUQ01AUF55 No results 19835 JY8QFUQ01BTU1O productive (see comment) Homsap IGHV4-30-4*03 F, or Homsap IGHV4-31*06 F (see comment) 749 82.27 181/220 nt 81.36 179/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARVWVAGSRDENFDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tctcgggtggttccatgacgagtactaatttctactggagttgggtccgccaacgctcagggaagggcctAggagtggCtttggatacatctatcacagtgggggcacctattacaacccgtctctcaagagtcgacttgacctgtcattagacgcgtctaataatgttttctccctgaaattggcctctgtaaccgccgcggacacggccgtatattactgtgcgagagtgtgggtggctggctctcgagacgagaactttgactcctggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19836 JY8QFUQ01AWCEG unproductive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARERGNSYGEIDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19837 JY8QFUQ01B8Z3T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-15*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKRLRGTVVVVDATPSPSTTG in-frame + cctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaaagattacgggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19838 JY8QFUQ01CYJO3 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctgattcagcttcagtacctaGtaacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19839 JY8QFUQ01CR76J productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt 83.71 185/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagtccccagggaagggtctggagtggattggaagtgtctattatCggggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19840 JY8QFUQ01BO89E productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 1 8 8 13 8.8.13 [1.17.38.11] CATYGRFSFSPLDYW in-frame + gtctggattcgacttcagtagttatggcttccattgggtccgccaggctccaggcaaggggctggagtgggtggcttttatgtggactgatggaggagaaatcacctacgcagactccgtgaagggccgattcaccatttccagagacaatgtcaagaagacagtgtatctgcaaatgagcggcctgagagtcgaggacacggctgtctattattgtgcgacttacggaagattctcgttttctccccttgactactggggccagggaacccttgtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagagcttcttccccca 19841 JY8QFUQ01DR4DC productive (see comment) Homsap IGHV3-69-1*01 P 912 92.06 197/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 7 13 8.7.13 [2.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene in CDR1-IMGT at codon 27 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 30 of V-REGION: 'AT' (2 nucleotides at position 18 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 80 in the user submitted sequence), (do not cause frameshift) agtctctggAattcaccATtcaggtgactacagcatgaactgGggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatGactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgcctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19842 JY8QFUQ01AYO67 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtatcgtggaactc 19843 JY8QFUQ01BQNDH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactGatgccatgagctgggtccgccaggctccGagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19844 JY8QFUQ01CBA31 productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 967 94.44 204/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19845 JY8QFUQ01CLR05 unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD4-23*01 ORF 1 8 8 18 8.8.18 [2.16.38.11] CARVGGNRGVRWYVGT*LLG in-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) gtgtctggattcagtttcagtagctttggcagcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatctggtatgatggaactaataaatattatgcagactccgtgaagggccgattcaccatctcgagagacaattccaagaacacactgtttctgctcatggacagcctgacagccgacgacacggctgtctattactgtgcgagagtcggggggaaccgaggagttcgctggtatgttggaacttgactactgggggccagggggaccctggtcaccgtctccgcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 19846 JY8QFUQ01BSVHI No results 19847 JY8QFUQ01DU91L productive (see comment) Homsap IGHV3-7*01 F 951 92.73 204/220 nt 92.27 203/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.17.38.11] CATDDSNGWDEVADYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); agcctctggattcaccttGcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacggatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19848 JY8QFUQ01AYDD7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARRSGRDGGWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggattcacctttgtcgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctccaaagacggttccaagaatacgatgtatctgcaaatgaacaccctgagagacgacgacacggccatatattactgtgcgagacgaagtgggcgtgatgggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19849 JY8QFUQ01C0UPE unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 901 90.41 198/219 nt 89.04 195/219 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.17.38.11] CSKDTFGREDY## out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctctggattctccgtcagtaAgttactggatgcactgggtccgccaggctccaGGgggaaggggctggGagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19850 JY8QFUQ01BF2P2 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19851 JY8QFUQ01CMI13 productive (see comment) Homsap IGHV3-48*03 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcataGcattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19852 JY8QFUQ01COL8L unproductive Homsap IGHV3-7*03 F 860 88.53 193/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARDRYSSDSSYYMP#NWLDPW out-of-frame + cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19853 JY8QFUQ01CAGS9 No results 19854 JY8QFUQ01CZ8WX productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19855 JY8QFUQ01BDIEE productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*04 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-15*01 F 2 8 7 21 8.7.21 [1.17.38.11] CARRIQGHCRGGSCSRNNWFDPW in-frame + ctatggtgggtccttcagtggttactactggagttggatccgccagcccccagggaaggggctggagtggattggggaaatcaatcatagtggaagcaccaactacaactcgtccctcaagagtcgagccaccatctcagtagacacgtccaagaagcagttgtccctgaacgtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacggattcaaggacattgtaggggtggtagttgctccaggaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19856 JY8QFUQ01BDPKN unproductive Homsap IGHV3-33*03 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDGEQWLVWTL#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19857 JY8QFUQ01ARIMM productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1070 97.77 219/224 nt 97.32 218/224 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.37.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 79 of V-REGION: 1 nucleotides (from position 148 in the user submitted sequence), (cause frameshift) tccggggacagtgtctctaccaacagggctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 19858 JY8QFUQ01CX2HK productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgatgtcgtggaactcag 19859 JY8QFUQ01BD58O productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19860 JY8QFUQ01BQUWB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19861 JY8QFUQ01AL9ZT productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt 84.33 183/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19862 JY8QFUQ01A3U10 unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVRGYYGGQYFDS## out-of-frame + ctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19863 JY8QFUQ01BAZ4Q productive Homsap IGHV1-2*02 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARCLWISGTYHFDFW in-frame + tggatatactttcaccgaccattatgtttactggatgcgacaggcccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19864 JY8QFUQ01ANNUC productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.37.11] CAGSGRDPYGINVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 171 in the user submitted sequence), (cause frameshift) ggcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19865 JY8QFUQ01CB1XO productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19866 JY8QFUQ01BC36T unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 153 53.89 97/180 nt 8 7 X 8.7.X [1.17.26.X] null - No rearrangement found cctctggattcgccttcagtacatatatcatgaattgggtccgccaggctccagggaaggggctggagtgggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19867 JY8QFUQ01CEAUW No results 19868 JY8QFUQ01A4IHW productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 919 89.47 204/228 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 10 15 8.10.15 [3.17.38.11] CVTGVKASGGAHAMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcagcctctggattcagtttcagagacgcctggatgaattgggtccgccagtctccagggaaggggctggagtgggttggccgtgttaaaaggaaaactgatggtgggacgtcggaatatgctgcattcgtgaaaggcagattcaccatctcaagagatgattcagaaaacacactgtatctgcaaatgaacagcctggaaatcgacgacacagctgtgtatcgttgtgtcacaggagttaaggcttcggggggggctcacgctatggacgtctggggccaagggaccgcggtcatcgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcagcccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19869 JY8QFUQ01BRR78 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 99 61.9 39/63 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDRELHYQHLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctgggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19870 JY8QFUQ01B6TA3 productive Homsap IGHV4-4*07 F 872 89.77 193/215 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 7 12 8.7.12 [1.17.38.11] CARFSSYGDTFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctgatgggtccatcggaagttactactggacttggatccggcagcccgccgggaaggcaatggagtggatcgggcgtgtctttagaactgggaacacgaattacaacccctccctcaagagtcgggtcaccatgtcagttgacacgtccaagaatcaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgttttactgtgcgagattctcgtcctacggtgacacctttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19871 JY8QFUQ01C71PP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19872 JY8QFUQ01BQCJG productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-21*02 F 3 9 7 13 9.7.13 [1.17.38.11] CARGEMTAEYYFDYW in-frame + tctctggtggctccatcagcagtgttaactggtggagttgggtccgccagcccccagggaaggggctggagtggattggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19873 JY8QFUQ01B0TU1 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - ctctggattcagcttcagtagctacagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatctattagcaccaccagtagtaccataggctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19874 JY8QFUQ01BOB1S unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARVMREHYYGAGNYPWGGMEV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcacctttaacaactatgccatgacctgggtccgccaggctccggggaaggggctggagtgggtctcagctatcagtggcagtggcggtaccacttactacgcagactccgtgcagggccgcttcaccatttccagagacaatcacgaaaacaccctgtatctggaaatgagtagcctgagagccgaggacgcggccgtctattactgtgcgagagtgatgagggaacattattatggagcggggaattatccctgggggggaatggaagtctggggccaggggaccacggtgcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19875 JY8QFUQ01DP79K unknown (see comment) Homsap IGHV1-2*02 F (see comment) 759 83.64 179/214 nt 81.78 175/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'TC' (2 nucleotides at position 81 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'C' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift); tggatacatcttcaatgacttctacatatattgggtgcgacaggCcccctggacaagggcttgagtggatgGggatgggtTCaacccctaatagtcgtgtcacagactatgcagagaaatttcagggcagggtcaccatgaccggggacccgtcccgcagcacagtccacctgaaactgaccCcgcctgaagtcggacgacacggccgtctattactgcgcgagaggtctctcctcagcatcccccgaccagcccccaaggtcttccccgctgagccctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19876 JY8QFUQ01AL2ZJ unproductive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19877 JY8QFUQ01ACXLB productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [1.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtaccaagGttcatgagctgggtccgccaggctccagggaaGggggctggagtgggtctcagtaaCtttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 19878 JY8QFUQ01C3MZ0 No results 19879 JY8QFUQ01C4X7F No results 19880 JY8QFUQ01C3ZLL productive (see comment) Homsap IGHV3-11*01 F 955 93.15 204/219 nt 91.32 200/219 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 8 8 19 8.8.19 [2.17.38.11] CVRRGLGDTVMVPFRITSTTG in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'G' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 208 to 208 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaagGgggctggagtggatttcatacattagtggGgagtgcgactaccatatcctacgcagactttgcgaagggccgattcaccatctccaGgggacaacgccaagaactcggtgtatctgcaaatgaacagcctgagagccgaggacacgGgccacgtattattgtgtgaggcggggtctgggggatacagttatggttccgtttcgtattacttcgactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 19881 JY8QFUQ01BD4LD No results 19882 JY8QFUQ01AJ3EX productive Homsap IGHV3-48*01 F 1004 95.87 209/218 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARVGATLSFDVW in-frame + cctctggattcaccctcagtagctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtattagtagtggtaccatatactatgcagactctgtgaagggccgattcaccatctccagggacaatgccgagaactcactgtatctgcaaatgagcagcctgagagccgacgacacggctgtgtattactgtgcgagagtgggagcgacgctttcttttgatgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19883 JY8QFUQ01DM135 No results 19884 JY8QFUQ01DWQ32 No results 19885 JY8QFUQ01B14S8 productive (see comment) Homsap IGHV3-33*05 F (see comment) 742 82.87 179/216 nt 82.41 178/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.16.38.11] CVKGRGYNDYGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaagggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19886 JY8QFUQ01C12ZF No results 19887 JY8QFUQ01AMWC7 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19888 JY8QFUQ01BDD3D No results 19889 JY8QFUQ01BGI3K productive (see comment) Homsap IGHV4-61*02 F 807 85.0 187/220 nt 84.55 186/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.38.11] CARENYYGSGSYGRAWFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); ctctggaggctccatcagcagtggaagctacttctggacctggatccggcagcccgccgggaaggatctggagtggattaggcgcttctacagtagtgacagtgtcgactacaacccctccctcaggGggtcgagccaccatttcagcggacacgtccaagagccagttctcccttaatctgaagtctgcgaccgccgcagacacggccgtttattactgcgcgagagagaattactacggttcggggagttatgggcgggcctggtttgactactggggcccgggaatccaggtcaccgtctctgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19890 JY8QFUQ01C0H80 productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19891 JY8QFUQ01C1K22 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 794 84.62 187/221 nt 84.16 186/221 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFESW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tttccggtgactccatcaccagtactaattattactggggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattatcgggggacccagtacctcaacccgtctctccacaatcgagtcaccatatccattggcacgtccaagacccaattctccatgagactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacatcggtcttttggagtgataattgttaactactttgagtcctggggacaggggaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 19892 JY8QFUQ01BY231 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 929 91.4 202/221 nt 90.95 201/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgGggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcacgcacccagccagatgggaacgtgtcatcgcctgctggtccagggcttcttccc 19893 JY8QFUQ01DB79A productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19894 JY8QFUQ01DQP7X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19895 JY8QFUQ01BU39A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctggagttcagcctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19896 JY8QFUQ01BD1DU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19897 JY8QFUQ01COU9I productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 707 80.73 176/218 nt 78.9 172/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [2.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); tagtctctgggttcGaccatcagtCacgtactccatgggCctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgGcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19898 JY8QFUQ01CPKDU productive Homsap IGHV3-30*15 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGAYHFDSSSYIGAGW in-frame - cctctggattcaccttcagtagttatgctatgcactgggtccgccaggctccaggcaaggggccagagtgggtggcagtcatagcatatgatagaagtagtcagtattatgcagactccgtgaggggccgattcaccatctccagagacgattccgagaagacactgtatctacagatgagcagcctgagagctgaggacacggctacatattactgtgtgagaggggcgtatcactttgacagtagtagttacattggcgcgggctggggccagggaaccccggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19899 JY8QFUQ01ADJKJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame - cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19900 JY8QFUQ01DWHEJ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); gcctctacattcGccctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19901 JY8QFUQ01C8H4R unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 417 82.11 101/123 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta 19902 JY8QFUQ01DQ5MO unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CTREVGATDY## out-of-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19903 JY8QFUQ01BNMQ9 No results 19904 JY8QFUQ01DACAZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 846 88.02 191/217 nt 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.37.11] CIMDLVGRADYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) cctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaagGgggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgcgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19905 JY8QFUQ01BICKU unknown (see comment) Homsap IGHV2-5*01 F 1062 93.03 227/244 nt 92.62 226/244 nt 10 7 X 10.7.X [9.17.38.X] null + No rearrangement found in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgctccttctctgggttctcgctcagtaccgatggggtggctgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcaattattggaataatgacaagcgctacaggtcttctctgaagggcaggctcaccatcaccaaggacacctccaaaaaTccaggtggtccttacaatgaccaacatggaccctgcggacacagccacatattattgtgcacgcagaccatgttactctgatacccggtggttaccactgtttctttgactcctgggggccccggggaacccctggtcaccggtctccacagcatcccccggaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 19906 JY8QFUQ01CBE2T unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 862 89.67 191/213 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [X.17.38.11] CARRDVGLHAFDL## out-of-frame + tggatccaatttaactacgactggatcggctgggtgcgccagatgcccggtaaaggcctggagtggatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggcccaggggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcctgggcttcttccccca 19907 JY8QFUQ01BIJC2 productive Homsap IGHV3-13*01 F 957 94.39 202/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaacttcttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctccctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc 19908 JY8QFUQ01CW4B2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 914 91.28 199/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 9 7 9 9.7.9 [1.17.38.11] CARLKRKFDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'ACTG' (4 nucleotides at position 34 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tgtctggtggctccatcagcagaagtactttctACTGggggctggatccgccagcccccCAgggaagggggctggcgttgattgggagtatctataacaatgggggcCacctactacaacccgtccctcaagagtcgagtcaccatatcagtggacacgtccaagaatcagttctccctgaagctgagttctgtgaccgccgcagacacggctatatattactgtgcgagactgaagaggaaatttgactcttggagccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagccacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19909 JY8QFUQ01ALQL0 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19910 JY8QFUQ01DFGZK unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CARLPFIVVVTGAFFG##FDYW out-of-frame + stop codons in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); tggatacatctttaccaattactggctcggctgggtgcgccagatgcccggCaaaaggcctggagtggatggggatcatctttcctgctgactctgatgcccgatacagcccgtccttccaaggccaggtcaccatctcaatcgacaagtccatcaacaccgcctacctgcagtggagcagcctgaaggcctcggacgccgccatatattactgtgcgagactcccctttattgtggtggtgactggtgcgttttttgggacactttgactattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19911 JY8QFUQ01A6P66 unproductive Homsap IGHV3-7*01 F 978 94.09 207/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CAISSGFLLDG#YW out-of-frame - aggctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtgggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19912 JY8QFUQ01DII08 productive (see comment) Homsap IGHV3-11*01 F 832 87.5 189/216 nt 87.04 188/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 24 8.8.24 [1.17.37.11] CARDCHVDILTGYYRGSPPSCGLGVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 193 in the user submitted sequence), (cause frameshift) ctctggattcaagctcggtgactactatatgaattggatccgccaggctccagggaaggggctggagtgggtttcatatattagtcttggtggtagccccacatattatgcagactctgtgaagggccgattcaccatctccagggacaacgccaacaattcactatatctacagatgagtgccctgagagcgaggacacggccgtatattattgtgcgagagattgtcatgtcgatattttgaccggttattatcggggttcgcctccttcttgcggtctgggcgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19913 JY8QFUQ01DEK7J unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 156 to 156 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccAaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaaacggcgaccttgactactgggggccaggggaacccctggtcacccgtctcctccagcatcccccgaccagcccccaaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19914 JY8QFUQ01B8CGD productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 990 95.39 207/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [1.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctacaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19915 JY8QFUQ01BZYQ8 unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 921 92.52 198/214 nt 92.06 197/214 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [0.17.38.11] CARXGGMVRGLIITLQILGT#YYCVMDVW out-of-frame + in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacatgttcaccaactactatatacactgggtgcggcaggCcccctggacaagggcttgagtggatgggaataatcaaccctagtggtggtagtacaaagaacacacagaagttccagggcagagtcaccatgagcagggacacgtccacgaacacagtctacatggagttgagcggtctgagaactgaggacacggccgtgtattactgtgcgaganccgggggcatggttcggggacttattataaccctacaaatcctgggtactcctactactgcgttatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19916 JY8QFUQ01CL5PF productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19917 JY8QFUQ01CCCJ0 unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 650 76.92 170/221 nt 76.47 169/221 nt 10 7 X 10.7.X [2.16.38.X] null - No rearrangement found Low V-REGION identity (76,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtagtagttactactgggcctggatccgccagccccagggaaggggctggagtgccttgggagcatcttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccttatccgttgacacttccaagaaccagttctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 19918 JY8QFUQ01DBQJG unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcaaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19919 JY8QFUQ01AUJTS No results 19920 JY8QFUQ01A3WJG No results 19921 JY8QFUQ01ABDK7 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDRFPMVREKIAP#EYW out-of-frame + stop codons ctctggattcacctttaggaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaggagcacgctgcatatgcaaatgaacagcctgagagccgaggacacggccgcatattactgtgcgaaagaccgttttcctatggttcgggaaaaaatcgccccctgagtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacacggcccctgggctgcctggtcaaggactacttcccccgaacccggtgacggtgtcgtggaactcag 19922 JY8QFUQ01BQ15A No results 19923 JY8QFUQ01ANDRJ unproductive (see comment) Homsap IGHV3-30*01 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD4-17*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDAQC*ALLLLRYG#VW out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggGggctagagtgggtggcagttatatcatatgatggaagtaataaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgagagatgcccaatgttaggcactactactactacggtatggatgtctggggccaagggaccacggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19924 JY8QFUQ01BM0GO productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 830 88.21 187/212 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 1 8 7 20 8.7.20 [X.17.38.11] CVRDGRRTYNSGWYSLAAFDIW in-frame - tgtctgccatcagcagtggtaactggtggagctgggtccgccagcccccagggaaggggctggaatggattggagaaatctcttatagtgggaccaccaagtacaaccggtccctcaagagtcgagtcaccatatcactagacacgtccaaaaaccatttctccctgcagctgacttctgtgaccgccgcggacacggctgtctattattgtgtgagagatggtcgccggacctataacagtggctggtattcgttagctgcttttgatatctggggccaggggacagtggtcaccgtctcttccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19925 JY8QFUQ01CWSU1 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcacccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19926 JY8QFUQ01C4JPO unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CATRNKSGN*YA##DYW out-of-frame + stop codons in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctctggactcaacattggcaactatgacatgacctgggtccgccaggctcctgggaaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccggttcaccatctccagagacaactcccagactacgctgTtttttggagatgagcagcctgagagacgaggacacggccgtatattactgtgcgacaaggaataaaagtgggaattagtacgcctgttgactactggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 19927 JY8QFUQ01AVWT3 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt 94.12 208/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD1-26*01 F 2 10 7 X 10.7.X [1.17.38.11] CARLVG##WVDPW out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctctggtgactccatcaccagtagtaattactactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggagtgtctattatactgggagtacccactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaaggtgacttctgtgaccgccgcagacacggctgtgtataactgtgcgagactggtgggggcactgggtcgacccctggggccagggaaccctggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 19928 JY8QFUQ01BXAYL productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccntgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19929 JY8QFUQ01DCHN6 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccaTgggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19930 JY8QFUQ01CLUTY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19931 JY8QFUQ01C8YVG unproductive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [0.17.38.11] CAGDRGSGFWGGSYRPN#YGLDVW out-of-frame + tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcgggggtccggtttttggggtggttcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 19932 JY8QFUQ01C2ZLH unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*02 F 2 8 8 X 8.8.X [1.17.38.11] CARARATTRGELSSN#YGMDVW out-of-frame + cgtctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagcccgcgccaccacaaggggggagttatcgtcaaatctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 19933 JY8QFUQ01DCXWU No results 19934 JY8QFUQ01CL3D8 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) gcctccgggattcacctttagtagtttctggatgcactgggtccgcaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19935 JY8QFUQ01BDZXU productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 999 95.85 208/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 7 8 13 7.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) cctctggattcaagtttgagattccggcatgagctgggtccgccaagctccaGgggaaggggctggagtgggtctctggtattaattggaatggGtggtaagacaggttatgGgagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctgacagcacccccccaaagatgggaacgtggtccgtcgcatggccctggtccagggcttcttcccccag 19936 JY8QFUQ01DRNLO productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19937 JY8QFUQ01BET09 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccatctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19938 JY8QFUQ01CBOUS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 84.4 184/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 75 of V-REGION: 'AG' (2 nucleotides at position 130 to 131 in the user submitted sequence), (cause frameshift); gctccggtttcacgtttgacaactatgccatgacttgggtccgccagactccagggaaggggctgcagtggctctcaactattactgcttatgggactctcacatactacgctgcctccgtgaagggccAGggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19939 JY8QFUQ01BW5V9 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-13*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARGVGQQLPPLDW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 95 of V-REGION: 1 nucleotides (from position 188 in the user submitted sequence), (cause frameshift) tctctcgtggctccatcactccttcctactggagctggatccggcagcccccagggaagggactggagtggattggatatatctatgacagtgggagtaccaagtacaacccctccctcaagagccgagtctccatatcaatagactcgtccaagaaccagttctccctggagctgttctctgtgacgctgcggacacggccatatattactgtgcgagaggggtggggcagcaactgccccccttagactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 19940 JY8QFUQ01AI0OF unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 514 92.44 110/119 nt 8 8 X 8.8.X [1.17.5.X] null - No rearrangement found cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagaccca 19941 JY8QFUQ01BL9YR No results 19942 JY8QFUQ01B6PRR productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19943 JY8QFUQ01ASGTL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 84.79 184/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDPGNYWGYYYDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); gtctggattcacctttagtgattatgccttgagctgggtccgccagactcccgggaaGggggctggagtggatctcagAaaatcactggtgatggcggtaacaaatactatgcagactccgtgagggaccggttcaccatctccagagacaactccaagaatattttgtatctgcagatgagcagcctgagagccgaagacacggccatgtattactgtgcgagagatccgggaaattattggggatactattatgactcttggggcctgggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19944 JY8QFUQ01B8JIN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19945 JY8QFUQ01AT3U1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + ctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19946 JY8QFUQ01ABNG3 productive Homsap IGHV4-39*02 F 839 86.88 192/221 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.17.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19947 JY8QFUQ01C29JI productive Homsap IGHV4-4*07 F (see comment) 683 80.0 172/215 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARECTNEAGGPRHLDSW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01C29JI ; 8 AA in Homsap_IGHV4-4*07), and low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggccccatcaatagtagtgactactattggacttggatccggcagcccgccgggaggggactggaatgggtcgggcgtgtcttcatgaatggccttaccgactacaatccatccttcggcagccgtctcaccatgtccattgacatgtcgaagaaccaattctccctgaagttgacctctgtgaccggcgctgacacggccctttattactgtgcgagagaatgtactaatgaggctggcggaccgagacacctggactcctggggccacggaactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 19948 JY8QFUQ01DUSSF productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 777 85.05 182/214 nt 83.64 179/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARNRGYTPASGLASW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'CG' (2 nucleotides at position 160 to 161 in the user submitted sequence), (cause frameshift); tggatacattttcacccagtcctatatAgaatggggtgcggcaggcccctgggcaagggcctgagtggatgggaataatcagtccaagggttggcaccGacaacctacgcacacaagttccagggcagaatcaccgtgaccatggacacgtccacgacgCGacagtctacatggagctgagcagcctgacatctgacgacacggccatttactattgtgcgagaaataggggttacaccccagcgtctgggcttgcctcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19949 JY8QFUQ01C13DG No results 19950 JY8QFUQ01C9V29 productive (see comment) Homsap IGHV4-39*03 F 893 89.14 197/221 nt 88.24 195/221 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [2.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'TGG' (3 nucleotides at position 74 to 76 in the user submitted sequence), (do not cause frameshift); gtctccggtggctccatcaacagtagaaAattattattggggctggatccgccanccccccagggaagggtttTGGgagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19951 JY8QFUQ01ABAX4 productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggGggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19952 JY8QFUQ01B9HOL productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 19953 JY8QFUQ01BGX18 No results 19954 JY8QFUQ01BGZ0J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19955 JY8QFUQ01BPJLB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYFYYFDYW in-frame + cctctggattcacctttagccactatgccgtgacctgggtccgccaggctccagggaagggtctggagtgggtctcaactattagtggtagtgatggtagcacgtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagaagtatcactatggttcggggacttacttctactactttgactactggggccagggaaccctggtcaccgtctcctcagccatccccgcacccagccccaaggttccttcccgctgacgcctccgaagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 19956 JY8QFUQ01AL5BM unproductive (see comment) Homsap IGHV3-9*01 F 922 92.13 199/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWY#YFEYW out-of-frame + stop codons tctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 19957 JY8QFUQ01DKUU6 productive (see comment) Homsap IGHV3-9*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggGggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 19958 JY8QFUQ01BTIG6 productive Homsap IGHV3-66*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame + cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19959 JY8QFUQ01B8SWU productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARSLGHDSGDKRGFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); tctctgttgactccatcCagtaatttctattggagctggatccggcagcccccagggaagcgactggagtggattggatatatcgattacagtgggaccaccaagtacaacccctccctcatgagtcgactcaccatatcactagacacgtccaagaagcagttgtccctgaaggtgacctctgtgagtgctgcggacacggccgtctattactgtgcgagatccctcggccatgactccggtgacaaacggggctttgactactggggccagggaatcccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19960 JY8QFUQ01ATWYV unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 904 91.2 197/216 nt 90.28 195/216 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.16.38.11] CVRAGFGELSGFDC## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'GCTGGGA' (7 nucleotides at position 62 to 68 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 75 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggGCTGGGAgtggggtcagtctgggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctgggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 19961 JY8QFUQ01AUEO7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 828 87.1 189/217 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGFSAWGQDAFDIW in-frame + ctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19962 JY8QFUQ01AOUX0 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 19963 JY8QFUQ01B77AO unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 80 51.13 68/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcacctttaacctctatgtcatgcactggttccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19964 JY8QFUQ01ANXIN unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 181 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRGQGNGAG#DYW out-of-frame - cctctggattcaccttcagtaactactggatgcactgggtccgccaagctccagggaaggggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagaggacaagggaatggagcgggattgactactggggtcagggaaccctggtcaccgtntcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19965 JY8QFUQ01CNRF9 unproductive (see comment) Homsap IGHV3-7*01 F 733 95.06 154/162 nt 94.44 153/162 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 8 0 X 8.0.X [1.17.27.11] CAKGGW*RRP*LL# out-of-frame + stop codons in CDR2-IMGT, from codon 56 of V-REGION: 55 nucleotides (from position 82 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggctggtaacggcgaccttgactactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggctcagggcttcttccccca 19966 JY8QFUQ01B1Y8J productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactatatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccc 19967 JY8QFUQ01AL8DZ No results 19968 JY8QFUQ01CHQY5 productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*05 F 893 89.59 198/221 nt 88.69 196/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 10 7 15 10.7.15 [1.17.38.11] CARGRTVVTVIDYIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcggtagtacCtaactactggagctggattcggcagcccccagggaagggactggaattcattgggtatatctattccagtgggaggaccaactacaaccCcctccctcaagagtcgagtcaccatgtcagttgacatgtccaggaaccagttcaccctcaaattgacctctgtagccgctgcggacacggccgtctattactgtgcgagaggacgaacggtggtgactgttattgactacattgactattggggtcagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19969 JY8QFUQ01BW5CI productive (see comment) Homsap IGHV3-11*01 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19970 JY8QFUQ01CARI1 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.09 202/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19971 JY8QFUQ01AMH9V productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [1.17.38.11] CACYFDSNGFFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggTaaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaatggtttctttgactactggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 19972 JY8QFUQ01CZC9J unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNRCWPTLVLLRYGRFG# out-of-frame + tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19973 JY8QFUQ01CF54U productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 884 88.69 196/221 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-19*01 F 2 10 7 16 10.7.16 [1.17.38.11] CTNDHSMAVSAKHAFDVW in-frame + tctctggtgcctccatgagcagtagtgcatactactggggctgggtccgccagacccccgggaaggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctaagcatgcttttgatgtttggggtccagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19974 JY8QFUQ01DLSCT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19975 JY8QFUQ01AWCAC unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt Homsap IGHJ3*02 F 191 86.0 43/50 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [2.17.38.11] CAARIDSVITG#AFDIW out-of-frame - ggctctggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacctgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaattgatagtgtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgnttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19976 JY8QFUQ01CPM2Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1044 98.16 213/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKAGTYYYDSSGYYFLDYW in-frame + ctctggattcatcttcagtagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagccggcacgtattactatgatagtagtggttattacttccttgactactggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc 19977 JY8QFUQ01CCTPT No results 19978 JY8QFUQ01A79QG No results 19979 JY8QFUQ01CD0CK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccgagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19980 JY8QFUQ01BRREL productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 962 94.42 203/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame + tctctggtggctccatcgatagttactactggacctggatccggcagcccccagagaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccccc 19981 JY8QFUQ01BZQWU productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19982 JY8QFUQ01BHR4C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 19983 JY8QFUQ01AQIF3 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19984 JY8QFUQ01B7TY8 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 769 84.26 182/216 nt 83.33 180/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 7 8 13 7.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'GGC' (3 nucleotides at position 102 to 104 in the user submitted sequence), (do not cause frameshift); in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) ctctggattcattttagaaattttgccatgagttggctccgccaggcaccagggaaggggctggaatgggtctcgactatcagcagcactagtggtgacacGGCatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19985 JY8QFUQ01CA830 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattctaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 19986 JY8QFUQ01AHPUP No results 19987 JY8QFUQ01C2013 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 45 100.0 9/9 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found ctctggatt 19988 JY8QFUQ01CH27C productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 590 89.73 131/146 nt 89.04 130/146 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 6 17 8.6.17 [1.17.16.11] CAKKYHYGSGSYLYSFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 71 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) ctctgggttcacctttgcccactttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtggtgatgattccacaaatggacagcctgagagccgaggacacggccgtatatcactgtgcgaagaagtatcactatggttcggggagttatctctactcctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatcgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 19989 JY8QFUQ01C8W78 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 796 84.0 189/225 nt 82.22 185/225 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [2.17.38.11] CATDSPTGYYAFDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'GC' (2 nucleotides at position 164 to 165 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); gcctctgggttcGattttcagtgatgcctggatgagttgggtccgccaggcGtccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcGCaaaaaacatggtgtatctgcaattgaAaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 19990 JY8QFUQ01CJ7SX No results 19991 JY8QFUQ01A6LXJ productive Homsap IGHV3-23*05 F (see comment) 447 83.08 108/130 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (83,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19992 JY8QFUQ01CAABS unproductive (see comment) Homsap IGHV3-48*01 F 896 90.37 197/218 nt Homsap IGHJ1*01 F (see comment) 116 69.23 36/52 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARESTWVIYS*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggtaatttactcctgactcctgggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccgctgagcctctgcagcacccagcagcatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 19993 JY8QFUQ01B8T2M unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 715 91.18 155/170 nt 90.59 154/170 nt 8 7 X 8.7.X [2.17.22.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01B8T2M ; 8 AA in Homsap_IGHV3-11*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggGggccgattcaccatgtccagggacaacgccaagaactcactgtatct 19994 JY8QFUQ01B55MN No results 19995 JY8QFUQ01DF5ST productive (see comment) Homsap IGHV3-7*01 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gcctctacattcacgtttagtcggtattggatgagctggtaccgccaggctccagggaagggcctggGagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19996 JY8QFUQ01AIZSY unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARVDFYGSSKYK##FDPW out-of-frame - tctctggtaactccatcacagattattactggagctggctccggcagtctccagggaagggactggagtggattggaaatgtcttttacagtgggagagccaactacaacccctccctcaagagtcgagtcaccatatcagtagccacgtccaggaaccagttctccctgaagctcaggtctgtgaccactgcggacacggccatatattattgtgcgagagttgatttctatggttcgagtaaatataagggggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19997 JY8QFUQ01BIHI6 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 19998 JY8QFUQ01AC7XN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-17*01 F 2 8 8 14 8.8.14 [1.17.38.11] CASVDWVFDGDYGGYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'A' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgAaaaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagaggcgaggacacggccgtttattactgtgcgagcgtagattgggtgttcgacggtgactatggcggctactggggtcagggaaccccggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 19999 JY8QFUQ01A0JN8 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20000 JY8QFUQ01CXQLB productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + tctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 20001 JY8QFUQ01CHHSM productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.16.38.11] CGRPPLYSSGWQHPFNFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) gttctggatacaactttaccgactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtgatggggatcatctatcccggtgactctgatatcacatatagtccgtccttccaaggccaggtcaccatctcagtcgacaagtccatcagcaccgcctacctgcagtggaacagcctgaaggcctcggacaccgccatgtattattgtgggagacccccactatatagcagtggctggcaacatccttttaatttctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20002 JY8QFUQ01CRT5B No results 20003 JY8QFUQ01BZZTH unproductive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 975 95.33 204/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [0.17.38.11] CASAPLIVVDTTF#YW out-of-frame - in FR2-IMGT at codon 47 of V-REGION: 'GA' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgggtccgacaggcccctggGAccaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgcccctctgatagtagtggatactactttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagccaccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccca 20004 JY8QFUQ01BP5Z0 unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt 84.16 186/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - stop codons in FR2-IMGT at codon 39 of V-REGION: 'TGG' (3 nucleotides at position 38 to 40 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagtactcattactaattTGGgggctggatccggcagGCcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20005 JY8QFUQ01CKP5J No results 20006 JY8QFUQ01AD65R productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame - ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20007 JY8QFUQ01AYKFE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG## out-of-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggaccagggagccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20008 JY8QFUQ01CXSD6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtggcactaagacctactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20009 JY8QFUQ01CCYXO unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 900 90.78 197/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CATSRGSANWYPFDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtgcctctggcataaactgggtccgccaggctccagggaaggggctggaatgggtctcatccatcactgggagtagtagtcacacattttatgcagactcagtgaagggccgattcaccatctccagagacaacgccgagaactcagtgtacctgcaaatgaacagcctgagagacgaggacacggctgtttattactgtgcgacgagcagggggagcgccaactggtacccctttgaccactgggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20010 JY8QFUQ01AXDTZ No results 20011 JY8QFUQ01B46Q3 No results 20012 JY8QFUQ01A4YYJ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20013 JY8QFUQ01AKQ9T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 852 87.73 193/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - aggttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaataaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20014 JY8QFUQ01CAK37 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacttactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20015 JY8QFUQ01A33ZY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 883 89.5 196/219 nt 88.58 194/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CSKDTFGREDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'TA' (2 nucleotides at position 144 to 145 in the user submitted sequence), (cause frameshift); gcctctggattctccgtcagtaattactggatgcactgggtccgccaggctccagGgggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttTAacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggttttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 20016 JY8QFUQ01DBRIC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20017 JY8QFUQ01CFQCN productive (see comment) Homsap IGHV3-11*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 95 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20018 JY8QFUQ01BU7GA unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 503 93.04 107/115 nt 8 8 X 8.8.X [1.17.4.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagac 20019 JY8QFUQ01B8VRB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcacctttagaagctatgccatgagctGgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20020 JY8QFUQ01AY22T productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcagttttgcagattatggcatgggctgggtccgccaacttccagggaaggGggctggaatgggtcggtggtgttaattggaatgggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 20021 JY8QFUQ01ARXJY No results 20022 JY8QFUQ01AHS6H productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaAaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 20023 JY8QFUQ01AOBY5 No results 20024 JY8QFUQ01A0N8H productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1013 94.27 214/227 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGNYYDSGGLDYW in-frame - tctccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctgtgaaaggtcgaataactatcaagccagacgcatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtatattactgtgcaagagggggtaattactatgatagtggtggtcttgactattggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20025 JY8QFUQ01CXAUC productive (see comment) Homsap IGHV3-30*15 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaAaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20026 JY8QFUQ01CEKVC unknown (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 7 X 10.7.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtggtagttactactggagctggacccggcagcccgccgggaggggcctggagtggattgggcgtgtccataacagtggtagttccaattacaagccctccctcacgagtcgagtcaccatattagtagacacgtccaagaatcagttctcAcctgaagctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaagcgcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20027 JY8QFUQ01BBG2O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 12 8.8.12 [1.17.38.11] CSIRMLGTTGVDYW in-frame + cctctggattcacctttagcagctatgccatggactgggtccgccaggctccagggaaggggctggagtgggtctcagatattactggtggtggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggatacggccatatattactgttcaataaggatgctgggaactactggtgtggactactggggccagggaaccctggtcaccgtctcctcagcatccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20028 JY8QFUQ01A6XZ7 productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift); tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccTttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 20029 JY8QFUQ01BYHHU productive Homsap IGHV3-9*01 F (see comment) 770 83.94 183/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame - Low V-REGION identity (83,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgatcagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20030 JY8QFUQ01AVTMY productive (see comment) Homsap IGHV3-7*01 F 896 92.34 193/209 nt 91.87 192/209 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 6 8 14 6.8.14 [X.17.38.11] CVRGRDGVNFGEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tcatctttagtagacattggatggcctgggtccgccaggctccagGggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20031 JY8QFUQ01AM4BN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtagatattggatgcactGgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20032 JY8QFUQ01CCI5X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20033 JY8QFUQ01C3FR9 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ1*01 F 242 96.15 50/52 nt Homsap IGHD2-21*02 F 2 10 7 18 10.7.18 [1.17.38.11] CARSAYCGADCYSADYLQHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); tctctggtggctccgtGcagcagtaggggttactactggaactggatccgccagttcccagggaagggcctggagtggattgggaacatcttttacagtgggggcacctacgacaacccgtccctcaggagtcgaatttctatatcattagacacgtctaagaaccaattctccctgaagttgacctctatgaccgccgcggacacggccgtgtattactgtgcgagatcggcatactgtggtgctgactgctactcagctgattacctccagcactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20034 JY8QFUQ01CAN4N No results 20035 JY8QFUQ01C5UH4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKSLYQWLVHA#NWFDPW out-of-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20036 JY8QFUQ01AL2AF productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 20037 JY8QFUQ01BG2F7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CARGEFYYETSGRRGFDYW in-frame + ctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtcgcacgtattaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacactgtacttggaaatggacagtctgagagtcgaggacacggctatgtattattgtgcaagaggggaattttactatgaaactagtggtcgaaggggttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20038 JY8QFUQ01B51BL productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame - tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20039 JY8QFUQ01DNL8F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 20040 JY8QFUQ01BX3XY unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 135 55.56 75/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20041 JY8QFUQ01DRBO0 unproductive (see comment) Homsap IGHV3-43*01 F 1009 95.89 210/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKR*DWVL#YYFDHW out-of-frame + stop codons in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); gcctcaggattcacatttgctgaatataccatgcactgggtccgtcaagttccGggggaagggtccggagtgggtctctcttattagttGgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccCctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagccctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 20042 JY8QFUQ01BBWVB productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.37.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccaggGgaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgagactcat 20043 JY8QFUQ01AOR3J productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt 87.16 190/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDGGSYNRMDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'G' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); cgtctgggttcagtttcattgactatggcatacactgggtccgccaggctccaggcaAaggggctggagtggatggcaattatatggtatgatgggaaaaataaatattatgaagagtccgtgaagaaccgattcaccgtctccagagacaaGttccaagaacacggtgtatttggaagtgaatagtctgagagtcgacgacacggctgtgtattactgtgcgagagacggtgggagctacaacaggatggacctttggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20044 JY8QFUQ01AN9O8 productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.45 188/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 119 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtgggggtgtcgactacaaccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttccttccccca 20045 JY8QFUQ01DCIL6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacttgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggtgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20046 JY8QFUQ01BEUH6 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 840 88.32 189/214 nt 86.92 186/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 7 15 8.7.15 [2.16.38.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 2 nucleotides (from position 39 in the user submitted sequence), (cause frameshift) tctcctggtggTctccatcagtagttcctactggagttgatccgcagcccccagggaagggcctggagtggattggttatgtctattacTactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20047 JY8QFUQ01A9OIU unknown (see comment) Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F 84 51.52 68/132 nt 8 10 X 8.10.X [2.17.9.X] null - No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20048 JY8QFUQ01ARK4E unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARGDGYNFGGLDY## out-of-frame + cctctggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20049 JY8QFUQ01BSC8A unproductive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*03 F 843 87.27 192/220 nt 86.36 190/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 X 10.7.X [1.17.38.11] CATGVAGP#YFDSW out-of-frame + in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'G' (1 nucleotides at position 218 to 218 in the user submitted sequence), (cause frameshift); ctctggtggctccgtcagcagtggtaattactactggaactggatccgccaacccccagggaagggactggagtggattggatatatctactatgctggggccaccaacGtcgcccccctccctcaagaaccgagtcaccataacgagagacacgtccaagaaccaattttccctgaggttgacttctgtgaccgctgcggacacggccgtatattaGctgtgcgacgggcgtggctggaccccctactttgactcctggggccagggaaatctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20050 JY8QFUQ01BGMA3 productive (see comment) Homsap IGHV3-48*03 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) tctggattcaccttcagttcttatgccatgaactgggtccgcctggtccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20051 JY8QFUQ01C12H2 productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20052 JY8QFUQ01CYR71 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20053 JY8QFUQ01ABVQH productive (see comment) Homsap IGHV3-74*03 F (see comment) 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] YVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacGtttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattatgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20054 JY8QFUQ01B8303 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); tctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctacaaatgAaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20055 JY8QFUQ01BMNAR productive (see comment) Homsap IGHV3-21*04 F 952 92.34 205/222 nt 91.44 203/222 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [3.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gcagcctctggatttaccttcagtctctatagaatGgaactgggtccgccaggctccaCgggaagggactggagtgggtctcatccattactagtaccagtagttacatttattatgcagacccagtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtatctccagatgaacagcctgagagccgaggacacggccgtatattactgtgtgaggcgggtgtggggatacagctatggttccgtctcgtactattttgagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 20056 JY8QFUQ01DQWN3 No results 20057 JY8QFUQ01A10RN productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame + ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 20058 JY8QFUQ01A9GYP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt 85.25 185/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); gtctggattcacatttagaagctattccatgaattgggtccgGccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgCcacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaGgggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20059 JY8QFUQ01ALNYY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20060 JY8QFUQ01COZPR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20061 JY8QFUQ01AEDWR No results 20062 JY8QFUQ01CVCQ8 productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20063 JY8QFUQ01CF8T3 No results 20064 JY8QFUQ01B634H No results 20065 JY8QFUQ01CDTUO No results 20066 JY8QFUQ01A2B9H unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 935 91.07 204/224 nt 89.73 201/224 nt Homsap IGHJ6*04 F 126 66.67 42/63 nt Homsap IGHD3-22*01 F 2 8 10 X 8.10.X [1.17.38.11] CATDRPYYKKRCWPTLVLLRYGRF## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaagGgggctggagtgggttgcccgtgttaaaaacTaagactgacgatggggcaacagactacgctgcacccgtgaAaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaacgctgctggccgactctggtattactacggtatggacgttttggggcccaaagggaccacggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcag 20067 JY8QFUQ01C83BF productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + ctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggggggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20068 JY8QFUQ01CO79G No results 20069 JY8QFUQ01A0C2Y productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20070 JY8QFUQ01CTPBR productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame + ttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20071 JY8QFUQ01CQF9N productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtcccagggcttcttccccc 20072 JY8QFUQ01A6TG7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20073 JY8QFUQ01CAKSD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcccaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20074 JY8QFUQ01C03YM unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 20075 JY8QFUQ01BZUJK No results 20076 JY8QFUQ01AN8X4 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt 91.59 196/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [0.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'C' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccCccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 20077 JY8QFUQ01CTGRK productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-3*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARGGLEPRRLLG in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagccccgtagattattgggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctcccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20078 JY8QFUQ01AQAT6 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1009 95.89 210/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CVRGGLRWRPRTLLRP#YGLDVW out-of-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagagggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 20079 JY8QFUQ01B449A productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20080 JY8QFUQ01B1XKB No results 20081 JY8QFUQ01C42IH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20082 JY8QFUQ01CE84V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20083 JY8QFUQ01DFZV1 No results 20084 JY8QFUQ01C6K8W unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 497 84.17 117/139 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,17% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 20085 JY8QFUQ01B2MMF productive Homsap IGHV3-30*01 F 972 94.47 205/217 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20086 JY8QFUQ01A1201 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 20087 JY8QFUQ01CF7E5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 779 84.4 184/218 nt 83.49 182/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggCaaagggggctgtgtgggtctcacgcattGaaaaagtgtgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20088 JY8QFUQ01CPZUJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 20089 JY8QFUQ01C9W74 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 834 86.82 191/220 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKSPLSVAGTRQKLVR#PG out-of-frame - ggctctgacttgcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaaactggttcgacccctgggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20090 JY8QFUQ01DN49K productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20091 JY8QFUQ01CD8ZK productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacaacaccccccaagtggtcgtcgcatgcctggtccagggcttcttcccccag 20092 JY8QFUQ01CJ631 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CTKDSDMVGATYEDW in-frame + gctctggattcaactttaatacctatggcatgaattgggtccgccaggctccagggaagggactggagtgggtctcaagtatcactggtagcggtggtgatttgtactatgcagactccgcgaagggccggttcaccatctccagagacaattccaagaacaccctgtatctgcaaatagacagcctgagagccggggacacggccacatattattgtacgaaagacagtgatatggtgggagctacttatgaggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20093 JY8QFUQ01BBVC2 productive Homsap IGHV1-69*08 F (see comment) 768 84.58 181/214 nt Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARDCDTSGGRCPEAFKMW in-frame + Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggggggcacattcagcacacatattatcagctgggtgcgacaggcccctggacaaggacttgagtggatgggaagggtcatcccgataattaacacagcaaactacgcacacaattttcagggaagagtcacgatgaccgcggaaatgtccacgagcacggcctacatggaactgtccggcctaagatctgacgacacggccgtctactattgtgcgagagactgtgacactagcggcggtaggtgccccgaggcgttcaaaatgtggggccaagggacaatggtcatcgtcgtcttcagcctccacaagggcccatcggtcttccccctggcagccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact 20094 JY8QFUQ01B0LXB unknown (see comment) Homsap IGHV3-7*02 F 104 58.54 48/82 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found tctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20095 JY8QFUQ01DACHY unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1055 97.74 216/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 133 74.0 37/50 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [2.17.38.11] CARPYCGGDCHNRGAFDI## out-of-frame - cagcgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctgggggccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20096 JY8QFUQ01CE9AZ productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREVIPTATYGMDLW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) cgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttattggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20097 JY8QFUQ01CGIDS No results 20098 JY8QFUQ01AF664 productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20099 JY8QFUQ01BDUBV productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20100 JY8QFUQ01CCTJR productive Homsap IGHV1-3*01 F 822 87.38 187/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [0.17.38.11] CVRGRSPPGDWFDPW in-frame + tggatacaccttcactaattatgctctgcaatgggtgcgccgggcccccggacaaacttttgagtggctgggatggatcaactctgccaatggcaacacaaaatattctcagaagtttcagggcagagtcgccattaccagggacacatccgcgaggacaacttacatggaattgagcagtctgacatctgaagacacggcgacatattattgtgtgagaggaagaagtccgcccggcgactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20101 JY8QFUQ01AZJVY unproductive (see comment) Homsap IGHV3-7*01 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.16.38.11] CATSPLR*LLGRT#YW out-of-frame - stop codons in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) gcctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctcccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 20102 JY8QFUQ01BW5DS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 833 87.16 190/218 nt Homsap IGHJ3*01 F 187 86.0 43/50 nt Homsap IGHD3-16*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASLNTHAGPGAERSAFDVW in-frame + cctctggattcatcttcagtaactatagaatgaactgggtccgtcaggctccagggaaggggctcgagtgggtctcgtccatcaccagttccagtagttacatctactatgcagactcggtgacgggccgattcaccatctccagagacaactccaaggggtcactctatctgcacatgaacgaccttagggccgaagacacggctgtctattactgtgcgagcctaaacacgcacgcgggaccgggagccgagaggtctgcttttgatgtctggggccgagggacaagggtcaccgtctcctcaccatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 20103 JY8QFUQ01CNER6 No results 20104 JY8QFUQ01A1VSO No results 20105 JY8QFUQ01CPOAR No results 20106 JY8QFUQ01B4K3S productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20107 JY8QFUQ01CZANE productive Homsap IGHV4-61*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + ctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20108 JY8QFUQ01AKFDN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcacctttaccaactatggcatgagctgg 20109 JY8QFUQ01AY0TJ No results 20110 JY8QFUQ01DE64X unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDLRGLDYGIR#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctccggattcagtttcagtacttataacatgaattGgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaaggggtctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20111 JY8QFUQ01CX3E4 No results 20112 JY8QFUQ01AWT1P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1014 95.91 211/220 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRSEYSSSNWFDPW in-frame - agcctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20113 JY8QFUQ01CPA88 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactTatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20114 JY8QFUQ01ASUJY unproductive Homsap IGHV3-38*01 ORF (see comment) 111 59.09 52/88 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt X X X X.X.X [X.X.29.11] TVRNWKIAVGMKTP (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Low V-REGION score, and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctgaattaacgtttgacaattccaagaacatgttgtatttgcaaatgaacaacctgcgagggcgaggacacgggccgtttattactgtgcgaaactggaaaatagcagtgggaatgaagactcctggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20115 JY8QFUQ01DKB30 No results 20116 JY8QFUQ01DBO11 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD3-3*01 F 3 8 8 15 8.8.15 [2.17.38.11] CAKQTIFDYYYYGLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); gcctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaGggggctggagtgggtctctagtattagtggtaGggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20117 JY8QFUQ01CA0P8 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDAFEMW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctgggattcacctttgatgattttggcatgagttgggtccgccaagttccagggaaggGggctggagtgggtcgctggtatcagttggaatggaggcaaaacaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcattgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20118 JY8QFUQ01BI513 No results 20119 JY8QFUQ01DFEGX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 20120 JY8QFUQ01AKVHK productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 995 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPAGGSGAYEYW in-frame + cctctggattcaagtttgatgattccggcatgagctgggtccgccaagctccagggaaggggctggagtgggtctctggtattaattggaatggtggtaagacaagttatggagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttgcaaatgaacagtctgagagccgaggacacggccttgtattactgtgcgagaggccccgccgggggatctggcgcatatgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 20121 JY8QFUQ01CL52F productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20122 JY8QFUQ01DGMBS productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 984 95.79 205/214 nt 95.33 204/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CASAPSDSSGYYFSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagttactatatgcactgggtccgacaggCcccctggacaagggcttgagtggatgggaatgatcaaccctagtggcggaagcacaatctacgcacagaacttccagggcagagttgccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaggacacggccgtgtattactgtgctagcgccccctctgatagtagtggatactacttttcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20123 JY8QFUQ01CRLLH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 20124 JY8QFUQ01CM5UC unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDFTYAFDL## out-of-frame + cgtctggattcacgttcagtagttatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatcatctggtatgatggaagtaatcaatattatgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgaaagattttacgtacgcctttgatctctgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20125 JY8QFUQ01A5E5J productive (see comment) Homsap IGHV3-7*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.16.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 43 in the user submitted sequence), (cause frameshift) gacctctggattcacctttagtaaccattggatgaactgggtcgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20126 JY8QFUQ01ABNDS unproductive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPLGVGG#FDNW out-of-frame - stop codons in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'T' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataAaaccaagatggaggtgacaTgggcctatgtggGactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20127 JY8QFUQ01CCO0W productive Homsap IGHV3-30*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 1 8 8 9 8.8.9 [1.17.38.11] CAREGGGFDYW in-frame - ctctggattcagtttcagtagctatgcaatgcattgggtccgccaggctccaggcaaggggctagagtgggtgacagttatatcagctgatgcaactaccagtcactacgcagactccgtgaagggccgattcacccactccagagacaattccaagaacacgctgtctctgcaaatggacagcctgagacctgaagacacggctgtatattactgtgcgagagaggggggcggatttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20128 JY8QFUQ01DNK5V unproductive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 937 92.24 202/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKKPT*IGGPMI#YFDSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaGggggctagaatgggtggcttTttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacacttTtatctggaaatgaacagtctggacgctgaagacacggctgtgtattactgtgcgaaaaaaccgacctgaattgggggaccaatgatatttattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20129 JY8QFUQ01DJ82G unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 131 83.78 31/37 nt 8 X X 8.X.X [1.2.X.X] null + No rearrangement found cttctggattctcctttagcaactatgccctggcctg 20130 JY8QFUQ01ALVZH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcanttcccccgaaccggtgacggtgtgcgtggaactca 20131 JY8QFUQ01CAXMD productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 40 of V-REGION: 'T' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); tccggattcagtttcagtacttataacatgaaTttgggtccgccaggctccagggaaggGggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20132 JY8QFUQ01CHRYW unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKETTRQWLVPI#ALDVW out-of-frame + stop codons ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20133 JY8QFUQ01BD8LY productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame + ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20134 JY8QFUQ01DBP8Z No results 20135 JY8QFUQ01AFC3M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20136 JY8QFUQ01CJCW2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20137 JY8QFUQ01A313A productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20138 JY8QFUQ01B9OYE productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 995 93.39 212/227 nt Homsap IGHJ6*02 F, or Homsap IGHJ6*03 F (see comment) 179 77.05 47/61 nt Homsap IGHD3-9*01 F 2 10 9 12 10.9.12 [1.17.38.11] CVRDYDTLTLLDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctccgggggacagtgtttctaggaacaatgctgcttggaactggatcaggcagtccccgtcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaggtcgaataaccatcaacccggacacatccaagagccagttctccttgcagttgaagtctgtgactcccgaggacacggctgtgtactactgtgtaagagactacgatactttgaccctcttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20139 JY8QFUQ01B2EBO No results 20140 JY8QFUQ01CN5AJ productive Homsap IGHV3-30*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 1 8 8 9 8.8.9 [1.17.38.11] CAREGGGFDYW in-frame + ctctggattcagtttcagtagctatgcaatgcattgggtccgccaggctccaggcaaggggctagagtgggtgacagttatatcagctgatgcaactaccagtcactacgcagactccgtgaagggccgattcacccactccagagacaattccaagaacacgctgtctctgcaaatggacagcctgagacctgaagacacggctgtatattactgtgcgagagaggggggcggatttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20141 JY8QFUQ01BVY45 productive Homsap IGHV3-48*04 F 923 91.74 200/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20142 JY8QFUQ01AVQX3 productive (see comment) Homsap IGHV3-7*01 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [2.17.38.11] CATSPSDFDRRWGYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggatttagctttagaaccttttggatgagctgggtccgccaggctccagggagGggggctggagtgggtggccaacataaAagtcagatggaagtgacaaatggtatgtggactctgtgaagggccgattcaccatctccagagacaacgcgaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgacctcccctagcgactttgacagacgatgggggtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20143 JY8QFUQ01DAUGI unproductive (see comment) Homsap IGHV4-61*02 F 988 94.14 209/222 nt 92.79 206/222 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 1 10 7 X 10.7.X [2.17.38.11] CATVAXRG#AFDIW out-of-frame + stop codons in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'A' (1 nucleotides at position 205 to 205 in the user submitted sequence), (cause frameshift); gtctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatgGgggcgtatctataccagtgggatcaccaactacaaCcccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagAacacggccgtttattactgtgcgacagtggcgcnccgggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20144 JY8QFUQ01DGK9U productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDPQQILAEVNWFDPW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 87 of V-REGION: 'T' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); cctctggattcacctttcgcagctacgccatgagttgggtccgccaggctccaggaagggggctggagtgggtctcctcaatcagtggcagtggtgataaaacaaaatatgcagactccgtgaagggccgattcaccatctccagagacaatgcgaggaacactTttttatctgcatatgaacagcctcagagccgcggacacgggcgtctactattgtgcgaaagatcctcagcagatactggcagaagtaaactggttcgacccctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccagg 20145 JY8QFUQ01AEQTJ unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt 91.28 199/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 69 of V-REGION: 'GT' (2 nucleotides at position 115 to 116 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtcgttatagcatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggcagtagcacaagctacggggGTactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttggggatgtcaggctggttcgacccttgggggccagggaacccctggtctccgtctctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggctt 20146 JY8QFUQ01AHX2Q productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20147 JY8QFUQ01BZW00 productive Homsap IGHV1-69*06 F, or Homsap IGHV1-69*14 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-7*01 F 1 8 8 9 8.8.9 [0.17.38.11] CVIKTSYYDYW in-frame - tggaggcaccttcaacaccattacttttagttgggtgcgacaggcccctggacaagggctcgagtggatggggggggtcatccctctctttagtagaacaaattacgcagaaaacttccagggcagagtcacaattaccgcggacaagtccacgaccacagcctacatggagttgagcagcctgagatttgaggacacggccatgtattactgtgtgatcaaaactagttattatgactactggggcctgggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20148 JY8QFUQ01CEUBT unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-49*01 F or Homsap IGHV3-49*03 F or Homsap IGHV3-49*04 F or Homsap IGHV3-49*05 F 131 83.78 31/37 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found ctctggattcgtctttggcgactatgcgatgagctgg 20149 JY8QFUQ01BG853 productive (see comment) Homsap IGHV3-7*03 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [2.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctccggattcaAtttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20150 JY8QFUQ01BL2G8 unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 692 78.57 176/224 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 10 X 8.10.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (78,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcactgtcaataacgcctggatgacctgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgatggcgggacagcagactacgctccatttgtggacgacagattcaccatttcaacagatgattcaaaaaacacgttgtatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20151 JY8QFUQ01BOJ7D No results 20152 JY8QFUQ01DREVE productive Homsap IGHV3-7*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20153 JY8QFUQ01ACESU No results 20154 JY8QFUQ01BC7DQ unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 920 90.95 201/221 nt Homsap IGHJ6*01 F 229 84.13 53/63 nt 10 7 18 10.7.18 [1.17.38.11] IVRRGKWGDKPPFYYGMDVW (see Functionality comment) in-frame + stop codons, IMGT/JunctionAnalysis gives no results for this JUNCTION Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctgattgattgtncgacgagggaagtggggggacaaaccgcccttctactacggtatggacgtctgggggccaaggaccacggtcaccgtntcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20155 JY8QFUQ01ADOO5 productive (see comment) Homsap IGHV4-4*07 F (see comment) 688 80.09 173/216 nt 79.63 172/216 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD2-8*01 F 2 10 7 16 10.7.16 [2.17.38.11] CARECTNEAGGPRHLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gtctctggtggccCccatcaatagtagtgactactattggacttggatccggcagcccgccgggaggggactggaatgggtcgggcgtgtcttcatgaatggccttaccgactacaatccatccttcggcagccgtctcaccatgtccattgacatgtcgaagaaccaattctccctgaagttgacctctgtgaccggcgctgacacggccctttattactgtgcgagagaatgtactaatgaggctggcggaccgagacacctggactcctggggccacggaactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20156 JY8QFUQ01B21HW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 881 90.23 194/215 nt 88.84 191/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagCcccccagggaagggactgcagtggattgggttacatctatccagtgggagcaccaactacaaCcccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctCccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcacccctcctccaagagcacctctggggggccacagcggcccctggggctgccctgggtcaagggactacttcccccgaaccggtgacggtgtcgtggaact 20157 JY8QFUQ01AECRJ productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20158 JY8QFUQ01AM8RY unproductive Homsap IGHV3-48*01 F 1075 100.0 216/216 nt 98.61 213/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.16.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaagggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20159 JY8QFUQ01AEOIN unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.6 212/215 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARLGPGSGTDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20160 JY8QFUQ01BCTIC unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 177 85.42 41/48 nt 8 X X 8.X.X [1.6.X.X] null + No rearrangement found tctctggagtcactttcactaacgtgtggatgagttgggtccggcagg 20161 JY8QFUQ01AU7TR productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 89.77 193/215 nt 87.91 189/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift); cttctgggttcaccgtcagtagcaaGgttcatgagctCgggtccgcCcaggctccagggaaTGgggctgggantgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20162 JY8QFUQ01C416K No results 20163 JY8QFUQ01AOR8Z unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 880 90.61 193/213 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] CARTEYVSGWYIGGFD#PW out-of-frame + tatggtgggtcactcagttcttatttctggagctggatccgccagtccccagagaaaggactggagtggattggggaaatcaatcagagtggaaccaccaactacaacccgtctctcaggagtcgagtcaccatagcaatagacacgtccaagaaccagttctccctgaaggtgacctctgtgtccgccgcggacacggctgtctattactgtgcgaggaccgagtatgtcagtggctggtacatcggggggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctgccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 20164 JY8QFUQ01B8HJH productive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20165 JY8QFUQ01AYVGU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20166 JY8QFUQ01AKEAH No results 20167 JY8QFUQ01CC1DT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame + gcctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgagaacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtccgtcgcatgcctggtccagggcttcttcccccag 20168 JY8QFUQ01AF795 No results 20169 JY8QFUQ01BG2KS productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 791 83.93 188/224 nt Homsap IGHJ4*02 F 165 88.1 37/42 nt Homsap IGHD6-13*01 F 2 8 10 5 8.10.5 [1.17.38.11] CMAGGYW in-frame + Low V-REGION identity (83,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaatttcaatagtgccatgatgggctgggtccgccaggctccaggtaaggggctaaaatgggttggtcttattaagaccaatgcagatggtgggacaacaaattacgctgcacccgtgcaaggcagatttgtcatctcaagagaggattcagtaaataccctttatctgcaaatggacagcctgaaggtcgaagacacagccgtctattactgtatggcaggtggttactggggccagggagccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20170 JY8QFUQ01DEEV3 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 20171 JY8QFUQ01DMSA6 productive (see comment) Homsap IGHV3-66*02 F 953 93.95 202/215 nt 93.49 201/215 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD6-13*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARDSPYSSGWSDGFDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 150 to 150 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaatTtcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggctttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaag 20172 JY8QFUQ01A23OB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20173 JY8QFUQ01AWFQT productive Homsap IGHV3-48*01 F 923 91.74 200/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-9*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGNYYYFGMDVW in-frame + cctctggattcctcttcagtagctttaacatgaactgggtccgccaggttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccatctactactgtgcgagacaaactgggaattattattacttcggtatggacgtctggggccaagggactacggtcaccgtctcctctgcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20174 JY8QFUQ01B3UOA productive (see comment) Homsap IGHV3-7*01 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 18 in the user submitted sequence), (cause frameshift) gcctctggattcaccttagtacctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcatgatgcaagtgagaaatactatgtggactctgtaaaaggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20175 JY8QFUQ01B8M9T unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20176 JY8QFUQ01AOZL3 No results 20177 JY8QFUQ01ASD8L unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 497 84.17 117/139 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found Low V-REGION identity (84,17% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccacatactacgcagactccgtgacggtgtcgtggaactc 20178 JY8QFUQ01DJONI productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + cgtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactca 20179 JY8QFUQ01AU1D0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.37.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 100 of V-REGION: 2 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20180 JY8QFUQ01CAZ32 No results 20181 JY8QFUQ01DOK1D No results 20182 JY8QFUQ01B7EYY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagttcccactggatgcactgggtccgccAaagctccagggaaggggcttgtgtgggtcgcacgaatcaattctaatggaaaaagtgcaagttatgcggagtccgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20183 JY8QFUQ01C8DDQ productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 675 78.8 171/217 nt 77.42 168/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [1.17.37.11] CAREDIVREGLDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (78,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 215 in the user submitted sequence), (cause frameshift) tgtctggtggctccatcgccacttatcattggtggaattgggtccgccagACcccccggggaagggactggagtggattgGgggaagtctattatagtcgacagactaattacaacccgtccctccagagtcgcgttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattatgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccggaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20184 JY8QFUQ01CALA4 productive (see comment) Homsap IGHV4-61*07 F (see comment) 775 84.02 184/219 nt 83.11 182/219 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGHYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); gtctggtggctccgtcagcagtggAaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggtcattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20185 JY8QFUQ01AM31I unknown (see comment) Homsap IGHV3-74*03 F 126 54.81 74/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattcaccttcagtagctactggatgcactgggtccgccaagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20186 JY8QFUQ01A3NO6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagGggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgtgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgt 20187 JY8QFUQ01CHW1K productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20188 JY8QFUQ01CFK1J productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 20189 JY8QFUQ01C1CXV productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 921 92.52 198/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20190 JY8QFUQ01DJI9S unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggcccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20191 JY8QFUQ01CGJ0L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20192 JY8QFUQ01DJX4C productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 998 94.2 211/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcgaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20193 JY8QFUQ01AGKNE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtagttactggatgcactgggtccgccaaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20194 JY8QFUQ01BB204 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt 83.94 183/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); cctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaAaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgTtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20195 JY8QFUQ01CUAXD productive Homsap IGHV3-72*01 F 899 89.29 200/224 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGYDYW in-frame - cctctggcttcatcttcagtgaccactatatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagagttgcatctaacacttacgccacagaatacgccgcgtctttcaaaggcagattcgtcatctcaagagacaattcaaggaactcattgtttctccaaatgaacagcctgaaaaccgacgacacggccatgtattattgtgctagagatctgggcaatggctggggctatgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20196 JY8QFUQ01C9P1S unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgcctgagcctcgacagcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20197 JY8QFUQ01CPDLP productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 724 81.94 177/216 nt 81.48 176/216 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,94% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'CAG' (3 nucleotides at position 55 to 57 in the user submitted sequence), (do not cause frameshift); gtctcgagtgcctccatgatcagttactattggacctggattcggcagccccccCAGggaaggggactggagtggattgaggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20198 JY8QFUQ01CAUG4 productive (see comment) Homsap IGHV3-7*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaaaCgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgg 20199 JY8QFUQ01BBJ2G productive (see comment) Homsap IGHV1-3*01 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacagcttcactaactacaatatccattgggtgcgccaggCcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 20200 JY8QFUQ01A5C4M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 739 82.19 180/219 nt 81.28 178/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [2.17.38.11] CARYRVGDSLYYGLDGW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'ACT' (3 nucleotides at position 92 to 94 in the user submitted sequence), (do not cause frameshift); gcctctggattcatttttagaaattttgccatgagttggctccgccaggcaccagGggaaggggctggaatgggtctcgactatcagcagcACTagtggtgacacggcatattactcagactccgtgaggggccgcttttccatctccagagacaactccaagagcactctgttcttgcagatgaacagcctgagtgccgaagacacggccatttactactgtgcgagataccgtgtgggtgacagtctctactacggtttggacggctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20201 JY8QFUQ01B4ZZI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20202 JY8QFUQ01BVJ0N productive (see comment) Homsap IGHV3-7*01 F 823 87.04 188/216 nt 86.57 187/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-22*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKAGRGLIRPNNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); tctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaAGggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcagactccgtgaagggccgattcaccatctccagagacgattccaagaatacgctgtatctgcaaatgagcagcctgggacctgaagacacggctatatattactgtgcgaaagcggggcgtgggttgatacgacccaacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20203 JY8QFUQ01BBBFG productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20204 JY8QFUQ01A81PE unproductive Homsap IGHV3-23*03 F (see comment) 809 86.51 186/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-25*01 F 3 8 7 X 8.7.X [1.17.38.11] CTRELRMAAARDGVDI## out-of-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01A81PE ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggattcaccttcatcagttatggcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatcctgatgggactacacactatggagactccgtgaggggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggcccaaggcacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 20205 JY8QFUQ01BRWCE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame + gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20206 JY8QFUQ01CYW73 productive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 86.88 192/221 nt Homsap IGHJ4*03 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARERSASMGAARELDSW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 100 to 102 in the user submitted sequence), (do not cause frameshift); tctctggtggccCccatcggcagtggtgcctactactggacctggatccggcagcccgccgggaagggattggagtggctcgggcgtgtttatagtggtGGGgggatcatcaattacagtccctccctcaagagtcgaatcaccatgtcgatagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttatattactgtgcgagagaacgtagtgcctcgatgggcgctgcgagagaacttgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 20207 JY8QFUQ01CTE26 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20208 JY8QFUQ01DCVSS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgGggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 20209 JY8QFUQ01B0HVO No results 20210 JY8QFUQ01BD2L0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20211 JY8QFUQ01C3HRU productive Homsap IGHV3-9*01 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CAKATTAWYSGGLDVW in-frame + ctctggattcaactttgatgattacggcatgcactgggtccggcaacgcccagggatgggcctggagtgggtcgcaggtattagttataataatggccacaaagaatatgcggactctgtgaggggccgattcaccatctctagagacaacgccaggaagtccctgtatctgcagatggacagtctgagagttgaggacacggccttgtattattgtgcaaaggctacaactgcctggtattcaggcggtctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20212 JY8QFUQ01CZ0MA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame - tctggagttcactttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccaggagcccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20213 JY8QFUQ01DGX5I productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 2 8 8 11 8.8.11 [1.17.38.11] CAKVGNLYFFEYW in-frame + ctctggattcagcttcagtagctacagtatgaactgggtccgccaggctccagggaaggggctggagtggatttcatctattagcaccaccagtagtaccataggctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagacgaggacacggctgtgtactactgtgccaaagtgggtaacctgtatttctttgaatactggggccggggaaccctggtcaccgtctcccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20214 JY8QFUQ01BQARW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20215 JY8QFUQ01A53DH productive (see comment) Homsap IGHV3-48*01 F (see comment) 774 84.33 183/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [2.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) agcctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 20216 JY8QFUQ01CSQFL productive Homsap IGHV3-48*01 F 1080 100.0 217/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20217 JY8QFUQ01CRKLK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.38.11] CAKERDNNVLPVDSW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgaggggccggttcaccgtctccagagacaatttcaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20218 JY8QFUQ01AR0FB unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20219 JY8QFUQ01CNVVI unproductive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.91 200/220 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSITLTVVVMND#AFDVW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgattgcttttgatgtctggggccaagggacattgatcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 20220 JY8QFUQ01BWCR5 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 101 57.65 49/85 nt 8 2 X 8.2.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 20221 JY8QFUQ01C5GV2 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F 477 93.58 102/109 nt 92.66 101/109 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD4-17*01 F 2 8 X 15 8.X.15 [1.15.11.11] CAKNNNDFGDYDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 54 of V-REGION: 106 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttaaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20222 JY8QFUQ01C99YD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 770 82.38 187/227 nt 81.06 184/227 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [4.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 111 to 111 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); gtggccaatgtctgggattcacatttagaagctattccatgaattgggtccgGccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggggcgCcacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaGgggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20223 JY8QFUQ01AR5R2 productive (see comment) Homsap IGHV3-7*01 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [0.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) tctggatcacctttagcagctatgccatgacctgggttcgccaggctccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20224 JY8QFUQ01C15XA No results 20225 JY8QFUQ01C32U2 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD4-17*01 F 2 8 7 18 8.7.18 [1.17.38.11] CASLVTINDNGDYTWAFDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'TT' (2 nucleotides at position 48 to 49 in the user submitted sequence), (cause frameshift); tggatggtgggtccttcagtaataagtattggagttggattcgccagTTccccagggaagggggctagagtggattggagaaatcaaccaaagtggaagcaccaactacaatccgtccctcatgagtcgagtcaccatctccatagacacgtccaagatgcagttctccctgaagttgacctctgtgaccgccgcggacacggctgtctattattgtgcgagtttagtgaccattaatgacaacggtgactacacgtgggcttttgatgtctgggcccaagggacaatggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20226 JY8QFUQ01B0486 productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20227 JY8QFUQ01BTOHO No results 20228 JY8QFUQ01CB6VS unknown (see comment) Homsap IGHV4-4*07 F 796 85.65 185/216 nt 84.26 182/216 nt Homsap IGHJ6*01 F, or Homsap IGHJ6*02 F or Homsap IGHJ6*03 F or Homsap IGHJ6*04 F (see comment) 30 100.0 6/6 nt 8 7 X 8.7.X [2.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR1-IMGT at codon 35 of V-REGION: 'CAGTGG' (6 nucleotides at position 21 to 26 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 102 to 102 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); gtctctggaggctccatcagCAGTGGaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtggGgggtgtcgactacaaccccGtccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattact 20229 JY8QFUQ01CRRE7 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CAREKGSGPPTGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20230 JY8QFUQ01BNF8E No results 20231 JY8QFUQ01COUX7 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 977 94.5 206/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); gttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctCggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20232 JY8QFUQ01BMH14 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 718 82.16 175/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDWGGSFDRYYFDYW in-frame + Low V-REGION identity (82,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release caccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 20233 JY8QFUQ01APTJL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20234 JY8QFUQ01BNV0X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20235 JY8QFUQ01B0DBV No results 20236 JY8QFUQ01B9VA3 productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARKGLVPSMFFFDFW in-frame + tctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20237 JY8QFUQ01DGA6N unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 92 90.91 20/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattccctttcagcaa 20238 JY8QFUQ01BXB4P productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20239 JY8QFUQ01CN9HT productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 21 8.8.21 [0.17.38.11] CAGDRGPVFGVVHIGQIYGLDVW in-frame - tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcggggtccggtttttggggtggttcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20240 JY8QFUQ01BL4JX productive (see comment) Homsap IGHV3-7*01 F 851 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 159 81.25 39/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [2.17.38.11] CVRDRPGGWALDYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); gcctctggattcagttttagtgacttttggatgcactgggtccgccaggcnccagggaaTGggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20241 JY8QFUQ01CMP43 No results 20242 JY8QFUQ01C5LWY productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame + ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggccacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 20243 JY8QFUQ01CTB3A productive (see comment) Homsap IGHV4-34*10 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); tgtctggtgagtccttcactaattactactggagctggatccgccagtccccaggaaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccGaaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20244 JY8QFUQ01AATZ4 productive Homsap IGHV1-2*02 F 826 87.79 187/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [X.17.38.11] CARDGISMTLVRGVRPFDYW in-frame + ggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccagga 20245 JY8QFUQ01DKEXG unproductive Homsap IGHV4-59*03 F (see comment) 728 82.33 177/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD3-9*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREGPPISDIFDWIS##DPW out-of-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tttctggtggctccatcagaagttactattggagttgggtccggcagtccccagggacgggactggaatggattgggtacaagttctacagtgggcccgccaaatataatccctctctcgagggtcgagtcacaatttctatagacacgtcgaagagtcaattcttcctgaggatgacgtctgtcaccactgcggacacggccgtctattattgtgcgagagagggaccccctatttccgacatttttgactggatcagcaatcgacccctggggccagggaatcccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20246 JY8QFUQ01AWKLD No results 20247 JY8QFUQ01BR7ZQ No results 20248 JY8QFUQ01ACIZJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaataaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20249 JY8QFUQ01B455L unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 914 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccaggggaaccctggtcacagtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20250 JY8QFUQ01ARZQB productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1007 94.64 212/224 nt Homsap IGHJ6*01 F (see comment) 180 76.19 48/63 nt Homsap IGHD4-11*01 ORF 3 8 10 18 8.10.18 [1.17.38.11] CVRHEGTPVSDVGGYGMDVW in-frame + Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtggctctgctatgcactgggtccgccaggtttccgggaaagggctggagtgggttggccgtattagaagcaaagcttacaattccgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatttggaaatgaacagtttgaagagggaggacacggccgtgtattactgtgtgagacatgaagggactccagtaagtgatgtaggtggatacggcatggacgtctggggtcaagggtccacggtcaccgtctcctcagcatccccgaccagcccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccccc 20251 JY8QFUQ01B27YH unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccatggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctttcccccca 20252 JY8QFUQ01DGZF9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGKMVSTGMDV## out-of-frame - cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcgcgagggaagatggtgagcaccggtatggacgtctgggggccaagggaccacggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20253 JY8QFUQ01BINTH unknown (see comment) Homsap IGHV1-3*01 F 742 92.94 158/170 nt 92.35 157/170 nt 8 8 X 8.8.X [0.17.23.X] null + No rearrangement found in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); tggatacaccttcactagttTttagtatacattgggtgcgccaggcccccggacagaggcttgagtggatgggatggatcaacgcaggcaacggtcacacaaaatattcacagaagttccaggacagagtcaccattataagggacacatccgcgagcacagcctacatgg 20254 JY8QFUQ01A70MJ No results 20255 JY8QFUQ01BOUTJ unproductive (see comment) Homsap IGHV3-7*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + stop codons in FR2-IMGT at codon 54 of V-REGION: 'CC' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift); ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcCCcacataaaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 20256 JY8QFUQ01BTE28 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRRGW*RAD#DAFDIW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggatggtagcgggcagatatgatgcttttgatatctggggccgaggggctatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20257 JY8QFUQ01AQI41 No results 20258 JY8QFUQ01B6R3H No results 20259 JY8QFUQ01BU71A unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found cctgctggattcagttttagttcttatggcatgaactgggtccgccaggcgtccaggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20260 JY8QFUQ01DE6Z2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20261 JY8QFUQ01AODBY No results 20262 JY8QFUQ01A6BXT productive Homsap IGHV3-9*01 F 896 90.37 197/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRQAYYHDSSAYFFSRYWYFDLW in-frame + cctctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacgccaagaagtccctgtttctgcaaattaaaagtctgagagttgaggacacggccttatattattgtgtgaggcaagcgtattaccatgatagcagtgcttacttcttctcccgctactggtacttcgatctctggggccgtggcaccccggtcactgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20263 JY8QFUQ01B8IUW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + cctctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 20264 JY8QFUQ01CDA2Z productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 842 87.61 191/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacagcaaaaactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20265 JY8QFUQ01C7XX1 unproductive Homsap IGHV4-61*08 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-24*01 ORF 1 10 7 X 10.7.X [0.17.38.11] CARGRDAYKVGY## out-of-frame - in FR3-IMGT at codon 87 of V-REGION: 'G' (1 nucleotides at position 165 to 165 in the user submitted sequence), (cause frameshift); ctggtgactccgccagcagtggtgattcgtactggagctggatccggcagcccccagggaagggactggagtggattggatatatctataagagtggggacaccgattataacccctccctcaggagtcgagtcaccatatcagtggacacgtccaagacccagGttttccctgaagctgaactctgtgaccgctgcggacacggccgtgtattactgtgcgaggggaagagatgcctacaaggtgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20266 JY8QFUQ01B829A productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 935 91.07 204/224 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [4.17.38.11] CARGPRSRGYGMDVW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01B829A ; 7 AA in Homsap_IGHV3-53*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20267 JY8QFUQ01AIGWM No results 20268 JY8QFUQ01BSJ22 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20269 JY8QFUQ01B76XK productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-21*02 F 2 8 8 13 8.8.13 [1.17.38.11] CATIPSYCGGDCYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctttaccttgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgctagtggtttcatctactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtatactactgtgcgaccatcccttcgtattgtggtggtgactgctattactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20270 JY8QFUQ01C6LLM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-6*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSPIASRLYIDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaagggccggttcttcatctccagagacaattccaagaacactctacatctgcatatgagcagcctgagggccgaggacacggccacatattactgtgcgaaaggggactcgcctatagcgtctcgtctatatattgactcctggggccaggggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 20271 JY8QFUQ01BAL9L productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcCggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20272 JY8QFUQ01AQSJN unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccagtgacggtgtcgtggaactcag 20273 JY8QFUQ01AYH5R productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*06 F 900 90.78 197/217 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD3-3*01 F 3 8 8 22 8.8.22 [1.17.38.11] CARDFLAPNRFGVFDYYYYGMDVW in-frame + gtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaggggtctggaatggttggcaatgatatggtatgatggaaataaaaaatactacgcagactccgcgacgggccaattcaccatctccagagacaattctgagtacacgctgtctcttcaaatgaacagcctgagagtcgaggacacggctgtctattactgtgcgagggatttcttagccccgaatcgttttggagtgtttgactactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggccttcttcccc 20274 JY8QFUQ01ADPM4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20275 JY8QFUQ01CB22S unproductive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 995 95.41 208/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRYTDSWFNGNWFA#PG out-of-frame - cctctggattcacatttgatgaatatggcatgagctgggtccgccaatctccagggaaggggctggagtgggtctctggtattaattggaatggtgccagcataggttatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtttctgcaaatgaacagtctgagagccgaagacacggccttgtactactgtgtgagagacaggtataccgacagttggtttaatggaaactggttcgccccctgggggccagggaacccaagtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20276 JY8QFUQ01C74AC productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20277 JY8QFUQ01CGEVE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20278 JY8QFUQ01DK586 productive Homsap IGHV3-7*01 F (see comment) 738 82.49 179/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Low V-REGION identity (82,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20279 JY8QFUQ01CNIG1 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F (see comment) 196 88.0 44/50 nt Homsap IGHD6-13*01 F 1 8 7 14 8.7.14 [1.17.38.11] CARPTYSSGRDAFDTW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctatggtgggtccttcagtacttactactggacatGggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcggacacgggtgtgtattattgtgcgaggcccacatatagcagcggccgggacgcttttgatacctggggccaagggacgacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20280 JY8QFUQ01BFUCU No results 20281 JY8QFUQ01CT8CG productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARSRTFYGSANYW in-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20282 JY8QFUQ01AVNE7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 92.69 203/219 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARPFSGRWCFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'AT' (2 nucleotides at position 84 to 85 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtGctcacgaaATtcaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20283 JY8QFUQ01CIZDC productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame - cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20284 JY8QFUQ01CT1G7 productive Homsap IGHV4-59*10 F, or Homsap IGHV4-61*02 F (see comment) 560 71.74 165/230 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [6.17.38.11] CARERDKSGGGAGDFDSW in-frame + Low V-REGION identity (71,74% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccagtggcattattaatagcgaaggttttggtcgtttctactggaactgggtccggcagatcgacgggcaggggctggagtggatcgggcgtgtttatcgtgatgggatcacaaactacaatccctccttcgggacccgaataagtttgtcgttagactcgtccaagaggcagttttccctgaagttacagtctgtgaccgccgcagacacggccgtatatttttgtgcgagggagcgtgacaagtcgggcggcggggcgggcgactttgactcctggggccagggactcctggtcaccgtctcatctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 20285 JY8QFUQ01AZYPY unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-21*02 F 2 8 7 10 8.7.10 [1.17.38.11] CATLRGG*HSDY in-frame + stop codons tctctggtgcctccatcaggagttattattggagttggatccggcagcccccaggaaagggactggagtggattggttatattaattatgttggggacaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggctgacattcggactactgggccgggaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggccaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 20286 JY8QFUQ01CK0JO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.67 198/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20287 JY8QFUQ01B5S7F unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccagttttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20288 JY8QFUQ01BC3E1 unknown (see comment) Homsap IGHV3-74*03 F 99 52.59 71/135 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20289 JY8QFUQ01ASDKR productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + gtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20290 JY8QFUQ01BBGWR productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - ggctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20291 JY8QFUQ01DHJ8A productive (see comment) Homsap IGHV4-39*02 F 828 93.16 177/190 nt 92.11 175/190 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 10 7 10 10.7.10 [1.6.38.11] CARIVVRQFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 31 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggtgactccatttccagtactagttattactggGggctggattcggggggtatctattctagtgggaccacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaacaactacttctccctgaagctgagttctgtgaccgccgcagacacggctgtgtattactgtgcgagaatagtggttagacagtttgaccagtggggccagggaaccctggtcaccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20292 JY8QFUQ01DVDK3 No results 20293 JY8QFUQ01A8NL2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgga 20294 JY8QFUQ01ALPR0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*01 F 1 8 7 14 8.7.14 [2.17.38.11] CARCKSAGLVDWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcagcattagcgactatgccatggcctgggtccgccaggctccagggaaggGggccggagtgggtctcaagtgttactaatggttttggcacatactacgcagactctgtgaagggccggttcaccgcctccagagacaattccaagaacgcattgttcttggaaatgaacatcctcagagccgaggacacggccgtatattattgtgcgaggtgtaagtcggccggtttggtggactggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20295 JY8QFUQ01C4YII productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 768 82.96 185/223 nt 82.51 184/223 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [4.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); atgcaaagtctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctccatccaagcagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20296 JY8QFUQ01BXMZI productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDLW in-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtggtgtcgaatatggatgatgcttttgatttgtggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 20297 JY8QFUQ01C5P5J No results 20298 JY8QFUQ01BA216 productive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20299 JY8QFUQ01C2VFE unknown (see comment) Homsap IGHV3-13*01 F (see comment) 361 67.63 117/173 nt 8 7 X 8.7.X [1.17.24.X] null + No rearrangement found stop codons Low V-REGION identity (67,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ccgctggattcaccctcagttcctacgacatgcactgggtccgccagactacaggaaaaggtctggagtgggtctcaggtataagcactgacggtgacacatactattcaggctcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20300 JY8QFUQ01AJXDQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CAKGRPTASWIYLDDW in-frame + ctctggattcgctcttagcagctatgccatgacctgggtccgccaggccccagggaaggggctggagtgggtcgcatctattagtggtagtggtggtagcacatactatgcagattccgtgaagggccggttcaccatctccagagacaattccaagaacatgctgtctctgcaaatgaacggcctgagagccgaggacacggccttttattattgtgcgaaagggaggcctacagcttcttggatctaccttgacgactggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20301 JY8QFUQ01AX74V unproductive Homsap IGHV3-9*01 F 919 91.32 200/219 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CAKLTYYDVGDY## out-of-frame + cctcgggggttcacctttgatgatcatgccatgcactgggtccggcaagttccagggaagggcctagagtgggtctcaggcattagttggaacagtggtactaaagtctatgcggactctgtgaagggccggttcaccatctccagagacaacaccaagaactccctgtatctccaaatggacagtctgagagctgaggacacggccttgtattactgtgcaaaactcacatattacgatgttggtgactattggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20302 JY8QFUQ01B05AB productive Homsap IGHV4-4*01 F, or Homsap IGHV4-4*02 F or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 883 89.5 196/219 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-13*01 F 2 9 7 14 9.7.14 [2.17.38.11] CARDKDVTARGTFDMW in-frame - gtctctggtgtctccatcagtagtaattactggtggatttgggtccgccagtccccaggggaggggctggagtggattggagaagtctatcatactgggaccacctattacaacccgtccctgaagagtcgagtcaccctgtcagtagacaagtccaggaatcagttctccctggagatgacttctgtgaccgccgcggacacggccgtgtatttctgtgcgagagataaagacgtgacagctcgtgggacctttgatatgtggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20303 JY8QFUQ01CKX6X productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 889 91.08 194/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 6 12 8.6.12 [1.17.38.11] CASSVFSPGGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgc 20304 JY8QFUQ01CMYD1 unproductive Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGVTKARYGLDV## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctgggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20305 JY8QFUQ01B6ERE productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*02 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*08 F or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*16 F or Homsap IGHV3-30*17 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F (see comment) 210 83.61 51/61 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD3-16*01 F 2 X X 19 X.X.19 [X.X.20.11] CATDLVTSTPGVLDDAYALFG in-frame - Low V-REGION identity (83,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gaacactgtgtatctgcaaatgaacagtctgagagttgacgactcggctctatatcgctgtgcgacagacttggtgacctccacaccgggagtcctcgatgatgcttatgccctttttgggggccaagggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20306 JY8QFUQ01C5JTV unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 7 X 8.7.X [1.17.38.11] CTRGRSDAWELSDH## out-of-frame - tcgacgatgggtcctgcagaaactgcttctggagttggatccgccagtccccagggaaggggctggagtggattggggaggtcaatgatagaggaggcatcgactacaacccgtccctcaagagtcgagtcaccatatcattagacacgtccaacaaccaagtctccctgaggttgagctctgtgaccgccgcggacacggctgtgtattactgtacgcgagggcgatccgacgcgtgggaattatcggaccactgggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20307 JY8QFUQ01ABKI9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 3 10 7 12 10.7.12 [0.17.38.11] CARSRTFYGSANYW in-frame - ctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcgacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20308 JY8QFUQ01CP3ZC productive (see comment) Homsap IGHV3-11*01 F 798 85.0 187/220 nt 84.55 186/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 3 8 8 16 8.8.16 [2.17.38.11] CVRDGARRTNQWLAHDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); agcctctggattcagctttaatgccttctatatgggttgggtccgccaggctccaggaaaggGggctggagtggatttcgtacattaactctggtggtagtgacacatattacgcagactctgtgaagggccgattcaccatctccagggacaacgcctgggacacaatgtacttggaaatgaacagcctgagagccgaagacacggccgtctactattgtgtgagagatggcgctagaaggacgaatcagtggctggcccatgacttctggggccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20309 JY8QFUQ01CM1FF productive Homsap IGHV1-24*01 F 993 96.26 206/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20310 JY8QFUQ01AK0KO productive (see comment) Homsap IGHV3-72*01 F (see comment) 800 84.38 189/224 nt 83.93 188/224 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 1 8 10 12 8.10.12 [1.17.38.11] CARDLGNGWGLDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 54 of V-REGION: 'TG' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); cctctggattctccttcagggaccactatattgactgggtccgccaagctccaggaaagggactggagtggcttTGgcccgttctagaaccaaagcaaccggtggcgcctcagaatatgccgcgtctgtgaagggcaggttcaccatctccagagacgattcaaggaactcagtgcatctactattgaataacctgaaaagcgatgacacggccatgtatttctgtgctagagatctgggcaacggctggggcttggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20311 JY8QFUQ01CQQNC No results 20312 JY8QFUQ01C2IAV No results 20313 JY8QFUQ01ATFEQ productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 407 79.39 104/131 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame - Low V-REGION identity (79,39% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20314 JY8QFUQ01B4GVE No results 20315 JY8QFUQ01AUENE productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggc 20316 JY8QFUQ01AS6DO productive (see comment) Homsap IGHV4-39*02 F 920 90.95 201/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); tctctggtggGctccgtcagtaggagtccctactactggggctGggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20317 JY8QFUQ01AMI66 productive (see comment) Homsap IGHV4-4*07 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDSTGSLEDGLDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); tctctggtggctCccctcagtacttactactggaactgggtccggcagcccgccgggaagggactggagtggattgggcgtaaatatcccagtggggacaccaactataatccctccctcaaaagtcgagtcaccatgtcactagacacgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagggaaggattactatgatagtactggttccctcgaggatggtcttgatatctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 20318 JY8QFUQ01BOM4G productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 932 92.2 201/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [1.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctgcctcagcatccccggacccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 20319 JY8QFUQ01CUGKT unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggggggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 20320 JY8QFUQ01CDTYL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 811 85.84 188/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20321 JY8QFUQ01BM8I4 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame + tctctggtggctccatcagtagttcctactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20322 JY8QFUQ01B5HNR unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 86 78.57 22/28 nt 7 X X 7.X.X [2.X.X.X] null + No rearrangement found tctccgggggacagtgtctctaccaaca 20323 JY8QFUQ01BGHS2 No results 20324 JY8QFUQ01AHMW7 No results 20325 JY8QFUQ01CUYHV productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-22*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKGWNYHSATFWVLTTG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 79 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattTttcagagacaactccaaagacacgctgtatctgcaaatTgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaaccttttgggttttgactactgggggccagggaaccctggtcaccgtcgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20326 JY8QFUQ01AS1OO productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20327 JY8QFUQ01B35QV productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 899 91.16 196/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20328 JY8QFUQ01AWLSJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame + tctctggattcaccttcatcagttatggcatgagttgggtccgccagtttccagggaaggggctggagtgggtctcatctattagtgattatggtaataccgcattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtgggggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20329 JY8QFUQ01A9JML unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt 90.37 197/218 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); ctccaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatacCtggtggtagcaAcagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20330 JY8QFUQ01BU1XC No results 20331 JY8QFUQ01AMBSZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKEGPTLLTRPPLNW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgcccccctctcaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20332 JY8QFUQ01B9UWP unknown (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20333 JY8QFUQ01DKE1M productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20334 JY8QFUQ01BHEC4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 94.26 197/209 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARGRIVSVGMSGWFDPW in-frame + tcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20335 JY8QFUQ01BXE8C productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctctggattcaccttcGagtgtccatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20336 JY8QFUQ01CQFMR unproductive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + stop codons in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaaataaaaacaacatggaggtgaaaaCgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggaactcag 20337 JY8QFUQ01BMG0Y productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 797 85.32 186/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.15.38.11] CARRWARQRLVMDYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 2 nucleotides (from position 42 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) gtctctggtgactccatcagtagtactcattactattggggtgatccggcagcccccagggaggggactgagtggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20338 JY8QFUQ01DB8ET productive Homsap IGHV4-61*02 F 880 88.74 197/222 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [2.17.38.11] CARDFGGSYNLVAYW in-frame - gtctctggtgactccatcagtagtgattctcattactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20339 JY8QFUQ01CWLBM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame - in CDR2-IMGT at codon 62 of V-REGION: 'CG' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift); tctggattcactttcagtaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatCGgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20340 JY8QFUQ01BLYHV unknown (see comment) Homsap IGHV3-7*03 F (see comment) 756 82.95 180/217 nt 82.49 179/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 50 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggcGtggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20341 JY8QFUQ01BT61L productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CNTDLGGSWYTFYSDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 6 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) ctctggatacactgtcataaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttcccccaag 20342 JY8QFUQ01CIOJM productive Homsap IGHV4-61*03 F 152 66.25 53/80 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 141 77.08 37/48 nt Homsap IGHD3-10*01 F 1 X X 13 X.X.13 [X.X.26.11] CATVRHLGERIFDFW in-frame + tctctggggccaccatgagtagtttctactggagctggctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20343 JY8QFUQ01CLZV6 No results 20344 JY8QFUQ01C4TEY productive (see comment) Homsap IGHV1-3*01 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARDGESLGGDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); tggatacaccttcagtaattatgctatacattggttgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctagcacgggtaacaCcaaaatattcacagaagttccagggcagagtcaccattaccagggacacagccgcgaccacagcctacatggaattgagcagcctgaaatctgaggacacggccgtgtattactgtgcgagagatggggagtcactgggaggcgactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20345 JY8QFUQ01C3WWM productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20346 JY8QFUQ01DTQKC No results 20347 JY8QFUQ01CK7VZ productive (see comment) Homsap IGHV3-66*02 F 908 91.63 197/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaGggctccaggaaAagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20348 JY8QFUQ01CY4TY unknown (see comment) Homsap IGHV3-11*01 F 977 94.5 206/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccagcgggggatcacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20349 JY8QFUQ01ACUDT No results 20350 JY8QFUQ01CSGBR productive (see comment) Homsap IGHV3-7*01 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20351 JY8QFUQ01CDA9C No results 20352 JY8QFUQ01CEW0X productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20353 JY8QFUQ01C1AE4 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 169 76.27 45/59 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found ctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca 20354 JY8QFUQ01B4E92 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 70 of V-REGION: 'A' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'C' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaaAtccgtgcagggCccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20355 JY8QFUQ01CEO2I unproductive (see comment) Homsap IGHV3-7*03 F (see comment) 883 89.04 195/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [2.17.38.11] SRERCVSILL*QLL#DNW out-of-frame + stop codons Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttcgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaactc 20356 JY8QFUQ01B3QDR productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 20357 JY8QFUQ01ADJF1 unproductive (see comment) Homsap IGHV4-61*02 F (see comment) 780 84.09 185/220 nt 83.64 184/220 nt Homsap IGHJ2*01 F 85 62.26 33/53 nt Homsap IGHD3-16*02 F 1 10 7 X 10.7.X [1.17.37.11] CARGGGSR*YLVLRCL# out-of-frame - stop codons Low V-REGION identity (84,09% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift) tctctggttactccatcagtagtggtaatcactactggacctggctccggcagcccgccggggagccactggagtggattgggcgtatccacaccggtgggagtaccaattacaaccctccctccagagtcgagtctccatatcagcagatatattcgagaaccaattttccctgactctggagtctgtgaccgccgcagacgcggccacatattattgtgcgagaggtgggggttctcgttagtatctggtacttcgatgtctgggggccgtggcacccaggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 20358 JY8QFUQ01BLEMH productive (see comment) Homsap IGHV3-30*07 F, or Homsap IGHV3-30*12 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 389 90.53 86/95 nt 89.47 85/95 nt Homsap IGHJ3*02 F 241 98.0 49/50 nt Homsap IGHD5-18*01 F 3 X X 15 X.X.15 [X.X.31.11] CARSDEEYSYGDAFDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'ACTAT' (5 nucleotides at position 22 to 26 in the user submitted sequence), (cause frameshift); cgtctggattcaccttcagtaACTATgagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcggacgaggaatacagctatggggatgcttttgatatctggggccaagggacaatggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctgggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20359 JY8QFUQ01B23Q1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20360 JY8QFUQ01A2H8S No results 20361 JY8QFUQ01B8SW1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 242 94.34 50/53 nt Homsap IGHD2-21*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLKKKKKKKKK##WXFDLW out-of-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaactggtncttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtggacggtgtcgtggaactc 20362 JY8QFUQ01A7UAO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccgaagggcccagtcggtccttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20363 JY8QFUQ01ANM3M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1049 98.17 214/218 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 3 8 8 15 8.8.15 [1.17.38.11] CAKDRITIFSYNWFDPW in-frame + cctcgggactcatgtttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagatcgtattacgatattttcctacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggcccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaact 20364 JY8QFUQ01AFVJM productive (see comment) Homsap IGHV3-33*05 F (see comment) 761 83.49 182/218 nt 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,49% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaaaGatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20365 JY8QFUQ01BDUIT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 20366 JY8QFUQ01BBQX1 productive Homsap IGHV3-48*03 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20367 JY8QFUQ01CZ13L No results 20368 JY8QFUQ01BBZEX productive (see comment) Homsap IGHV3-7*01 F 892 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARVNKDSTDMW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtgactattggatgaggtggttccgccagcctccaggaagGggggctggagtgggtggccagcataaAaagaagatggaagtgagaaaggttatgtggactctgtgaagggccgcttcaccatcgccagagacaacgcccagaaatcactgtttttgcagatgaacagcctgagaggcgaggacacggctgtgtatttctgtgcgagagtcaacaaggactctactgatatgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 20369 JY8QFUQ01BX0T4 productive (see comment) Homsap IGHV3-48*03 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDKGWSGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'C' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggCttttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccaggagccactcagtgtggac 20370 JY8QFUQ01B0GQK productive Homsap IGHV3-11*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 18 8.8.18 [1.17.38.11] CVRRVWGYSYGSVSYYFEYW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaaaaactcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatactggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20371 JY8QFUQ01AJKU7 productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt 80.0 172/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccCgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 20372 JY8QFUQ01CTZSX unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); ctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20373 JY8QFUQ01C6PY2 No results 20374 JY8QFUQ01AAWJ6 productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20375 JY8QFUQ01BBO10 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [1.17.38.11] CTGLTYPDDYW in-frame + gtctggatttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 20376 JY8QFUQ01C560W No results 20377 JY8QFUQ01B4F27 productive (see comment) Homsap IGHV4-61*02 F 897 90.0 198/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) tctccggtggctccatcagtactggttattactactGggagctggatccggcagtccgccgggaagggactgaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20378 JY8QFUQ01DBGNA No results 20379 JY8QFUQ01AYJTA productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20380 JY8QFUQ01DM31W productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20381 JY8QFUQ01ADBUD productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaanttccagggaAagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccagaaccggtgacggctgtcgtggaact 20382 JY8QFUQ01CN7LI No results 20383 JY8QFUQ01CQPS9 unproductive Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.26 188/213 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDPYCSSTNCYPY## out-of-frame - in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggaTttcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20384 JY8QFUQ01AWCVF productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.38.11] CSRLLEEW in-frame + cctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtcggtcgtcgcatgcctggtccagggcttcttccccc 20385 JY8QFUQ01BT8WJ productive Homsap IGHV3-48*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame + cctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20386 JY8QFUQ01CITZZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKAGYSSARTHMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagcaattttgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagttgtgagtggtagtggcgatagaacagactacgcagactccgtgaagggccggttcactatctccagagacaattccaagagtacactattcctgcaaatgcacagcctgagagtcgaggacacggccgtatattactgtgcgaaagctggatatagtagtgcgcgaacccacatggacgtctggggccaaggggtcgcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20387 JY8QFUQ01B2ORR productive Homsap IGHV4-61*02 F 956 92.76 205/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20388 JY8QFUQ01AH2BL No results 20389 JY8QFUQ01A82FB productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 947 92.31 204/221 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD6-19*01 F 1 10 7 10 10.7.10 [1.17.38.11] CAAYDSGWYKHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctctggtggctccgtcaacagtggtgattactactggacctggatccgccagcaccctgggaagggcctggagtggattggatacatctattacagtgggagcacttactacaatccgtccctggagagtcgagttaccatatcaatagacatgtctaagaaccagttctccctgaaagtgagctctgtgactgccgcggatacggccgtgtatcattgtgcggcgtatgacagtggctggtacaaacactggggccagggaaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20390 JY8QFUQ01BFT1Q unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 644 77.06 168/218 nt 76.61 167/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagGggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20391 JY8QFUQ01DLOLN productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20392 JY8QFUQ01AB4RA unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1115 100.0 224/224 nt 99.55 223/224 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); ctgtctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20393 JY8QFUQ01BFAHV unproductive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ6*04 F (see comment) 108 66.67 36/54 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYDP## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20394 JY8QFUQ01B86US unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 836 87.91 189/215 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 2 8 7 X 8.7.X [1.17.38.11] CAKTTMTSVT#DWFDPW out-of-frame + tctctggggccaccatgagtagtttctactggagctgggttcggcagtccccagggaggggactggagtggattggatttgtttcttacagtgggcccaccaactacagcccctccctcaagagtcgtgtcaccctgtcaatggacacgtccaagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaacaacaatgacttcggtgactacgactggttcgacccctggggccagggaatgctgtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 20395 JY8QFUQ01C793Q unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD2-8*02 F 2 8 7 X 8.7.X [1.17.38.11] CARDWGWKLSIGIILTT## out-of-frame + Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggCacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattgggggtggaagctttcgataggtattattttgactactgggggccaggggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20396 JY8QFUQ01DKKB4 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 801 85.71 186/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccaccaaggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20397 JY8QFUQ01CH3UW unknown (see comment) Homsap IGHV1-2*02 F 911 92.45 196/212 nt 91.04 193/212 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.16.37.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 51 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 209 in the user submitted sequence), (cause frameshift) tggatacaccttcaccggctactatatgcactgggtgcgacaggcccctggacaaggccttgaaggatgggctggatcGaaccccaacactggtggcacaaattttgcacggcagtttcagggcagggtcgccatgaccagggacacgtccatcaacacagcctacatggacctgaccaggctgcaatctgacgacacggccgtttattctgtgcgagaatttcccatcggggggctagggtacgattttggacgtctggggccacgggacccacagtcaccgtctccctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20398 JY8QFUQ01DA4GB productive Homsap IGHV3-33*04 F (see comment) 703 80.37 176/219 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [2.17.38.11] CARDILDYW in-frame + Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcatttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaacctcag 20399 JY8QFUQ01CJUGP productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatcccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagactgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20400 JY8QFUQ01DF23E unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 777 85.05 182/214 nt 84.58 181/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CARERGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 188 to 188 in the user submitted sequence), (cause frameshift); ttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagcCcccgaggacacggccgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20401 JY8QFUQ01CUL3S productive (see comment) Homsap IGHV1-2*02 F 925 92.96 198/213 nt 91.55 195/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [X.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'TG' (2 nucleotides at position 41 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 82 to 87 in the user submitted sequence), (do not cause frameshift); ggatacaccttcaccgtctactatctattctgggtgcgacTGgggcccctggacAaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20402 JY8QFUQ01AFXVN productive (see comment) Homsap IGHV4-4*07 F, or Homsap IGHV4-59*03 F or Homsap IGHV4-59*08 F or Homsap IGHV4-59*10 F or Homsap IGHV4-61*02 F or Homsap IGHV4-61*06 ORF 448 88.6 101/114 nt 87.72 100/114 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 X X 13 X.X.13 [X.X.38.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); aattacagcccctccctcaagagtcgagtcaccaCtttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20403 JY8QFUQ01BICVC unproductive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-16*02 F 3 8 7 X 8.7.X [4.17.38.11] CARGAPFS**# out-of-frame + stop codons cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20404 JY8QFUQ01A5MP1 unproductive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1064 98.19 217/221 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARGGSSGWFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcagtggtggttactactggagctggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagcatctactacaacccgtccctcaagagtcgagttaccatatcagcagacacgtctaagaaccagttctccctgaacctgagctctgtgactgccgcggacacggccgtatattactgtgcgagaggcggtagcagtggctggtttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20405 JY8QFUQ01BPN8L productive (see comment) Homsap IGHV3-30*01 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-24*01 ORF 1 8 8 16 8.8.16 [2.17.38.11] CARDELPWDTIEYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); gcctctggattcaacttcaggacctattctatgcactggctccgccaggctccaggcaaggggActagagtgggtatcagttatttcatatgatggaactaagaagaattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctacaaatggacagcctgagacctgaggacacggctgtgtattactgtgcgagagatgaactgccttgggatacaatagagtattactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcacctgcctggtccagggcttcttccc 20406 JY8QFUQ01CG798 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 819 86.64 188/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ctctggattcacttttaggagtcatatgatgagttgggtccgccagactccagggaaggggctggaatgggtctcaagtattcgagccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaactccaagaacacgatgtatttgcaaatgcacagcctgagagtcgacgacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagccaccccagccagatggggaaacgtggtcatcgcctgcctcgtccagggcttcttcccccag 20407 JY8QFUQ01CLQHG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRVKRFGSGNVLFDYW in-frame + cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatactacgctgcctccgtgaagggccggttcaccctctccagggacaactccaacaacacggtgtatctgcaaatggacagtctgagagccgaagacacggccgtattttactgtgtgagagttaaacggttcggttcggggaatgtactctttgactactggggccagggaaccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20408 JY8QFUQ01DAGCS No results 20409 JY8QFUQ01B2E18 unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20410 JY8QFUQ01CLV9Y productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'CG' (2 nucleotides at position 52 to 53 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'GTC' (3 nucleotides at position 74 to 76 in the user submitted sequence), (do not cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccCGggggaggggctgggagtgggGTCagtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20411 JY8QFUQ01BS9UF productive (see comment) Homsap IGHV3-7*01 F (see comment) 728 82.33 177/215 nt 81.4 175/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.16.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 63 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 73 in the user submitted sequence), (cause frameshift) ctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccgagtgggtgccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagccttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20412 JY8QFUQ01BI2OX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 979 93.69 208/222 nt 92.79 206/222 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [3.16.38.11] CARGHSYYVSSGPDYW# out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 83 in the user submitted sequence), (cause frameshift) tgcagcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcattattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccCctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaacccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20413 JY8QFUQ01B9QB4 unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*07 F or Homsap IGHV4-61*08 F 806 85.32 186/218 nt 84.4 184/218 nt 10 7 X 10.7.X [0.17.38.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'TACGATCCCTCC' (12 nucleotides at position 109 to 120 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagagatttttattactggagttgggtccggcagcCccccagggaagggactggagtggcttggatatctctattacagagggagcaccaagTACGATCCCTCCtataatccctccctcgagagtcgagtcaccatttcagttgacccgtccaagaaccagttctccctgaagctaaactctgtgaccgctgcggacacggccgtgtattactgcgcgagagcctccaccaagggccccaatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 20414 JY8QFUQ01B8WSS productive (see comment) Homsap IGHV4-61*02 F 882 89.86 195/217 nt 88.48 192/217 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 9 7 17 9.7.17 [1.17.38.11] CARGKWGDKPPFYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'ATT' (3 nucleotides at position 27 to 29 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 3 nucleotides (from position 26 in the user submitted sequence), (do not cause frameshift) ctctggtgactccatcaccagtggtaATTattattggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcGatcgcacgcaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20415 JY8QFUQ01BOU3T unproductive Homsap IGHV3-30*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREGA#FDYW out-of-frame + ctctggattcagtttcagtagctatgcaatgcattgggtccgccaggctccaggcaaggggctagagtgggtgacagttatatcagctgatgcaactaccagtcactacgcagactccgtgaagggccgattcacccactccagagacaattccaagaacacgctgtctctgcaaatggacagcctgagacctgaagacacggctgtatattactgtgcgagagagggggcggatttgactactggggccagggaaccctggtgcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc 20416 JY8QFUQ01BM8LC unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 676 87.86 152/173 nt 8 8 X 8.8.X [1.17.23.X] null + No rearrangement found ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgcatcttc 20417 JY8QFUQ01BGUPV No results 20418 JY8QFUQ01A87OH unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 338 72.06 98/136 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01A87OH ; 8 AA in Homsap_IGHV3-74*01), and low V-REGION identity (72,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcccctttagtatgtattggatgtattgggtccgccaagctcccgggaaggggccggtatgggtcgcacgtatcagtaatgatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20419 JY8QFUQ01CA881 productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 795 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + tggatacaccttcagcgactactacatacactggctgcgacaggcccctggacaacgacttgagtggatgggatggctgaaccctaataatggtgacacagcttatggccagagctttcagggccgggtcaccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagccctttatttctgtgcgagaggcttttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20420 JY8QFUQ01CSWD7 unknown (see comment) Homsap IGHV3-7*02 F 118 60.24 50/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found cctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20421 JY8QFUQ01CUW2I unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + stop codons ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaaccggtgacggtgtcgtggaactcag 20422 JY8QFUQ01AHIIK unknown (see comment) Homsap IGHV3-66*02 F 748 92.49 160/173 nt 8 7 X 8.7.X [4.17.21.X] null - No rearrangement found tctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgta 20423 JY8QFUQ01CL149 productive Homsap IGHV1-8*02 F 822 87.38 187/214 nt Homsap IGHJ2*01 F 193 84.91 45/53 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [0.17.38.11] CTTKFGSDWQSDWYFHVW in-frame - tggagacacattccccagccatgacatcaactgggtgcgacaggccactggagaagggcttgagtggatgggacggatgaaccctaagactggtgacacaagctttgcacagaagttccacgatagagtcaccatgatcagtgacacctccataagtacagtgtacatggagctgagtagcctgagatctgaagacacggccatttactattgtacgacaaaattcgggagtgactggcaatcggactggtacttccacgtctggggccgtggcacctcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20424 JY8QFUQ01B2T9Q productive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20425 JY8QFUQ01ANXH8 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CAKDRVYGGGEPLDHW in-frame + cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20426 JY8QFUQ01BFNST productive (see comment) Homsap IGHV3-48*01 F (see comment) 759 84.11 180/214 nt 83.18 178/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20427 JY8QFUQ01B5ESG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - cctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20428 JY8QFUQ01DA37Z unknown (see comment) Homsap IGHV4-61*01 F 974 93.67 207/221 nt 92.76 205/221 nt 10 7 X 10.7.X [1.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 36 of V-REGION: 'CT' (2 nucleotides at position 28 to 29 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'CTCAAGTATAATC' (13 nucleotides at position 108 to 120 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagagataCTtttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacaCTCAAGTATAATCccctgtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtcgagagcatcccccgaccagcccccaaggtcttccccgctgagccctctgcagcaccccagcccagatggggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 20429 JY8QFUQ01A3BD5 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 940 93.06 201/216 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [2.17.38.11] CARAPRTATLLDPW in-frame - gtctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20430 JY8QFUQ01B3TLK unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDSPALCLGELF#DYW out-of-frame + in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaAatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattccccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20431 JY8QFUQ01A1GBM unproductive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKGRGYNDYGLDY## out-of-frame - Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactgggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20432 JY8QFUQ01BQ8XL productive Homsap IGHV4-61*02 F 983 94.12 208/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20433 JY8QFUQ01BKJWQ productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20434 JY8QFUQ01DI2D1 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 934 93.43 199/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [X.17.38.11] CARDRRGYSYEMDYW in-frame - ggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20435 JY8QFUQ01AHN93 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20436 JY8QFUQ01CBPM3 No results 20437 JY8QFUQ01DSQZ1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctcaggattcaccttcagtatctacaccatgaagtgggtccgccaggctccagggaagggactggagtgggtctcatccatcactagccgtggtgcttacatacactacgcagcctcagtgaggggccgattcaccatctccagagacaacgccagggactcactgtatttgcaaatgaacagcctgagtgccgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20438 JY8QFUQ01BS0BO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.37.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 92 of V-REGION: 1 nucleotides (from position 182 in the user submitted sequence), (cause frameshift) agcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20439 JY8QFUQ01ANL4J productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 942 92.27 203/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - agcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaactctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgggtcatcgcctgcctggtccagggcttcttccccca 20440 JY8QFUQ01APFZQ No results 20441 JY8QFUQ01BT21A unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F (see comment) 562 73.15 158/216 nt Homsap IGHJ2*01 F 36 66.67 12/18 nt Homsap IGHD5-18*01 F 3 8 8 X 8.8.X [1.17.38.6] PV## out-of-frame - Low V-REGION identity (73,15% ), and Cys 104 is missing this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20442 JY8QFUQ01AP004 unproductive Homsap IGHV4-61*02 F 1028 96.38 213/221 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [1.17.38.11] CARAPSYTNSHQHCDY## out-of-frame - tctctggtggctccatcaacagtggtagttactactggagttggattcggcagcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctattattgtgcgagagctccctcttataccaactcgcaccagcattgtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctccttccccca 20443 JY8QFUQ01DBQ71 productive Homsap IGHV3-33*03 F 927 92.17 200/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctcccagccaaggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 20444 JY8QFUQ01CQO1W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 20445 JY8QFUQ01CQILL productive Homsap IGHV3-48*01 F 820 86.3 189/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [2.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - tctctggctttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20446 JY8QFUQ01CN6JB productive Homsap IGHV3-7*01 F 1011 97.2 208/214 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [0.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggattcaccttcaggagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgacaaattctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20447 JY8QFUQ01DTDZS unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVRGGVSGAFRWGF*LL# out-of-frame + stop codons gcctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctgcaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggttttgactactgggggccagggaaccctggccaccgtctccgtcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctggctgcctggtcaggactacttccccgaaccggtgacggtgtcgtggaactca 20448 JY8QFUQ01CGD9R productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 7 8 17 7.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 14 in the user submitted sequence), (cause frameshift) gcctctggattcagtttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20449 JY8QFUQ01ABZFP productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 902 90.05 199/221 nt 89.14 197/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggagcgtctcctatggtggGgaacacctactacaaccCcgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20450 JY8QFUQ01CYDXA No results 20451 JY8QFUQ01CX4NS productive Homsap IGHV4-4*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-22*01 F 2 8 7 19 8.7.19 [1.17.38.11] CARGKDYYDTTGSLEDGFDIW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) tctctggtggctccataagaagttactattggagttggatacggcactccgccgggaagggactggagtggatcgggcgcatatatgacagtggtagtacaaactacaatccctccctcaagagtcgagtcagcatgtcagtggacacgtccaagaaccaggtctccctgaagttgatctctgtgaccgccgcggacacggccatgtattattgtgcgagagggaaggattactatgatacaactggctccctcgaggatggttttgatatttggggccaagggacgatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20452 JY8QFUQ01BCQMH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20453 JY8QFUQ01AK0D3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 872 89.77 193/215 nt 88.84 191/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift); tctctggtggctccatgaggaattattactggagctggatccggcagTcccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaaccCcctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaactc 20454 JY8QFUQ01CUK5M productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 888 89.55 197/220 nt 88.18 194/220 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [2.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AAA' (3 nucleotides at position 61 to 63 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); ggggtctggatacatctttaatatccactggatcgcctgGggtccgccagatgccccgggAAAagggcctggagtggatggGggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20455 JY8QFUQ01B9DK5 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 861 88.18 194/220 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-2*01 F 3 10 7 14 10.7.14 [1.17.38.11] CVRIVVPAHTMLFDPW in-frame + ttctggtggctacatcaccagtaccagttacttctggggctggatccgccagcccccggggaagggcctggagtggattggaagaatctattatagtggaaacacgtactacaatccgtccctcgggagtcgagtcaccatatccatagacacctccaagaagcagttttccctgaaattgcgctctgtgaccaccgcagacacggctgtgtacttctgtgtgaggatagtcgtaccagctcatacaatgttgttcgacccctggggccagggtaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggacgtggtcatcgcctgcctggtccagggctt 20456 JY8QFUQ01CG0LT productive (see comment) Homsap IGHV3-33*03 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARSDLSMVRDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'T' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); gcgtctggattcaccttcagtacctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgaTtttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20457 JY8QFUQ01DSX0H No results 20458 JY8QFUQ01DKNPA unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 467 68.37 147/215 nt 67.91 146/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.16.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (68,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift) tctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaaggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccagggcacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20459 JY8QFUQ01A7ITA No results 20460 JY8QFUQ01BZK8O unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CMNELGYCSGG## out-of-frame + gcctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggaccagggagccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20461 JY8QFUQ01CW0LD productive Homsap IGHV3-7*01 F 950 93.12 203/218 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20462 JY8QFUQ01BX4AA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20463 JY8QFUQ01A12BY productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattGcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20464 JY8QFUQ01AF4F3 productive (see comment) Homsap IGHV3-48*01 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctctggcttcagtttgagtacttataccatGgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggGactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20465 JY8QFUQ01BX5Z0 productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 966 92.83 207/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION gtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20466 JY8QFUQ01ATK0M productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20467 JY8QFUQ01ARPRF productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARPGVGASSFIDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gttctggatacagctttaccgcctactggatcggctgggtgcgccagatgcccgggaAaaggcctggagtgggtggcgatcatctatcctggtgactctgaaaccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcaccaccgcctacctgcattggaccagcctgaaggcctcggacaccgccatgtattactgtgcgagaccaggagtgggggcctcttctttcattgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20468 JY8QFUQ01AAWL0 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARGLYGYWYFDFW in-frame + gctctggattcatctttaatacctatggcatgacttgggtccgccaggctccaggaaaggggctggagtgggtctcaggtattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattcctgtgcgagggggctctacgggtactggtacttcgatttctggggccgtggcaccccggtcactgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20469 JY8QFUQ01CNI4Y productive Homsap IGHV3-9*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20470 JY8QFUQ01CGTBP productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRSEYSSSNWFDPW in-frame - cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgagaacgtggtcgtcgcatgcctggtccagggcttcttcccc 20471 JY8QFUQ01CSMYJ productive Homsap IGHV3-13*01 F 971 94.88 204/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + cctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 20472 JY8QFUQ01ATV4S productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 911 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [3.16.38.11] CTKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gcagcctctggaTttcgccttcagttggtattggagcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20473 JY8QFUQ01ATF2L productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20474 JY8QFUQ01CTI7H No results 20475 JY8QFUQ01AF66X productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVKGAGTTVNWFDIW in-frame + cctctggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20476 JY8QFUQ01BIF6M productive Homsap IGHV4-61*02 F 992 94.57 209/221 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARGSGSGSYSNLW in-frame - tctctggtggctccatcagcagtggtagtcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtatctatgccggttggaccaccaattacaatccctccctcaagagtcgagtcaccatatctatagacacgtcccagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggctcaggttcggggagttattctaacctctggggcccgggtaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20477 JY8QFUQ01BWN16 No results 20478 JY8QFUQ01A5FS2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 20479 JY8QFUQ01DN52V unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 765 83.41 181/217 nt 82.95 180/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT at codon 90 of V-REGION: 'G' (1 nucleotides at position 175 to 175 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaggtattggatgagctgggtccgccagtctccagggaagggactggagtggctggcccacataggaggagatggaagtgaggctggttatgtggactctgtgaggggccgattcttcatctccagagacaacgccaagagctccctctatctgcaGactgaacagcctgagccccgaggacacggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20480 JY8QFUQ01ALJ8H unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 447 93.14 95/102 nt 8 7 X 8.7.X [1.17.X.X] null + No rearrangement found cctctggattcacctttggcagctatatcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtaggggtgttgaca 20481 JY8QFUQ01B4A5P unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKDGARGGGSCF##SW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20482 JY8QFUQ01DPFBF unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 957 92.38 206/223 nt 91.03 203/223 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-19*01 F 2 8 10 X 8.10.X [1.16.38.11] CTTDIVSQWPVAL# out-of-frame + in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccggggaaggggctggagtggttggccggattaaaagcaaaactgatggtgggacaacagagcacgctgcacccgtgaAaaggcagattcaccatctcaagagatgactcaaaaaaGcacgctgtatctgcaaatgaacagcctgaaaaccgaagacacaggcgtttattattgtaccacagatattgtctcccagtggccggttgcgctggggccagggaacccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20483 JY8QFUQ01AY4V0 productive (see comment) Homsap IGHV3-23*05 F 826 87.79 187/213 nt 86.85 185/213 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 7 7 10 7.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggatcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20484 JY8QFUQ01APXHX productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccggagagccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20485 JY8QFUQ01BX1HA unproductive Homsap IGHV3-72*01 F 1088 98.66 221/224 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CLRPPRYD#PG out-of-frame + cctctggattaaccctcagtgaccactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactagaaacaaagctaacagttacaccacagaatacgccgcgtctgtgaagggcagattcaccatctcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtcttaggccgccgaggtacgacccctggggccaggggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20486 JY8QFUQ01AA0M8 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 950 93.12 203/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [1.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctgggaccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20487 JY8QFUQ01CHWP5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CSIRMLGTTG#DYW out-of-frame + cctctggattcacctttagcagctatgccatggactgggtccgccaggctccagggaaggggctggagtgggtctcagatattactggtggtggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggatacggccatatattactgttcaataaggatgctgggaactactggtgtgactactggggccagggaacccgtggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 20488 JY8QFUQ01AQAXR productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*13 F 909 91.24 198/217 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDDFYSSGNYGGFGMDVW in-frame + ctctggattcaccttcagtcactatggtatacactgggtccgccaggctccaggcaaggggctagattgggtggcatttatatcatatgatggaagtaatgagttttacgcagactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20489 JY8QFUQ01CWX1F No results 20490 JY8QFUQ01CPDWK productive Homsap IGHV4-61*02 F 920 90.95 201/221 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 14 10.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame + tctctggtgactccatcaccagtggtaattattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20491 JY8QFUQ01AEJD0 productive (see comment) Homsap IGHV4-61*02 F 876 90.19 193/214 nt 89.25 191/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 8 7 14 8.7.14 [1.17.38.11] CAREKVVIRPNWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CCAGTG' (6 nucleotides at position 18 to 23 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'T' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); ctctggtgactccatcaCCAGTGgtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaaTcccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaagtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20492 JY8QFUQ01AQYMP unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 824 86.7 189/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARCFSAWGSGCFRHL# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggatttatcttcagtgattatagcatgaattgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagatgcttcagtgcctggggctcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20493 JY8QFUQ01CZ7ZE productive Homsap IGHV4-61*02 F 888 89.55 197/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + ctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccgatgacggtgtcgtggaact 20494 JY8QFUQ01DBCZB productive (see comment) Homsap IGHV4-61*02 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 10 7 15 10.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'A' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctaAtttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20495 JY8QFUQ01CIMIR productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 944 93.49 201/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame - tctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20496 JY8QFUQ01DK73Q productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 662 77.98 170/218 nt 77.52 169/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD3-3*02 F 3 9 7 12 9.7.12 [1.17.38.11] CAREDIIREGLDRW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tgtctggtggttctactcgcactaaccattggtggaattgggtccgccagAccccccgacaagggactggagtggattggagaagtctataagagtggacagaccaactacaacccgtcactccagagtcgcgttgacctcttcattgacaactccaggaatcagatctccctaaatatgagagatgtgaccgccgcggacacggccgtctattactgcgcgagagaagacattattcgggagggccttgaccgctggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20497 JY8QFUQ01DU9MT unknown (see comment) Homsap IGHV1-3*01 F 863 89.3 192/215 nt 88.84 191/215 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); ctggatacagcttcactaactacaatatccattgggtgcgccaggGccccccggacaaggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctcggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 20498 JY8QFUQ01CYU9T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaaactca 20499 JY8QFUQ01BW40A unknown (see comment) Homsap IGHV1-2*02 F 491 87.4 111/127 nt 86.61 110/127 nt 7 8 X 7.8.X [0.17.9.X] null + No rearrangement found in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 9 in the user submitted sequence), (cause frameshift) tggatacatttcaccggctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcaggg 20500 JY8QFUQ01CSNEW No results 20501 JY8QFUQ01BKZA5 productive (see comment) Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20502 JY8QFUQ01AUOG5 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 838 87.21 191/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 7 8 10 7.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) cctccgggagttcaccttagtagtttctggatgcactGgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20503 JY8QFUQ01BNZIF productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame + ctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20504 JY8QFUQ01BXIFI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20505 JY8QFUQ01BKQKN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 813 85.2 190/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [3.17.38.11] CASFRVLESGYW in-frame - tcagtctctgggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20506 JY8QFUQ01CEKK5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20507 JY8QFUQ01BE7MC unknown (see comment) Homsap IGHV3-7*02 F 113 59.76 49/82 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20508 JY8QFUQ01B6OFV productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 20509 JY8QFUQ01CDM5K No results 20510 JY8QFUQ01DOM3L unproductive (see comment) Homsap IGHV4-61*02 F 857 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CAREGAWLHLQEV#FDYW out-of-frame + stop codons in CDR2-IMGT at codon 59 of V-REGION: 'ATT' (3 nucleotides at position 96 to 98 in the user submitted sequence), (do not cause frameshift); tctctgacgactccatcagcagtggcacttactactggagttggatccggcagcccgccgggaaggctccggagtggattggccgcttctatactATTactgggcgcaccaactacaatccctccctcgagagtcgagtcaccataacaagggacgtgtccaagaatcagttctccctgagactgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagggggcatggctacatctacaagaggtcttttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 20511 JY8QFUQ01DDD61 unproductive (see comment) Homsap IGHV3-7*01 F 980 95.35 205/215 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null + stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. ctggattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttgagattactggggccagggaacccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20512 JY8QFUQ01ANB8J No results 20513 JY8QFUQ01C1JXP unproductive Homsap IGHV3-48*01 F 1065 100.0 214/214 nt 99.53 213/214 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [0.16.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) ctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaagggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20514 JY8QFUQ01AOJA0 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt 89.5 196/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'GA' (2 nucleotides at position 103 to 104 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggttgggtggtcaAcgtagtaatacagggggggactgGAcacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20515 JY8QFUQ01B9QXU productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.37.11] CARKGLVPSMFFFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 192 in the user submitted sequence), (cause frameshift) ctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccgggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20516 JY8QFUQ01CUAUX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + ctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 20517 JY8QFUQ01B0M83 productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKVRRSGWSYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); cctctgggattcaccttctttacctatggcatgcactgGggtccgccaggctccaggcaaggGggctggagtgggtggcaattatatcatatgatgtaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagttgaggacacggctgtttattactgtgcgaaggtgcggcgtagtggctggtcctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20518 JY8QFUQ01AEOR4 unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt 90.18 202/224 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKKRCWPTLVLLRYGR#W out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggGggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaacgctgctggccgactctggtattactacggtatggacgttttggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20519 JY8QFUQ01CXDJA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKKYHYGSGTYLYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactgggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20520 JY8QFUQ01AS3A0 No results 20521 JY8QFUQ01B8UD2 No results 20522 JY8QFUQ01AY8EO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20523 JY8QFUQ01A4BAZ productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 20524 JY8QFUQ01BZQW7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20525 JY8QFUQ01BHF8T productive Homsap IGHV4-4*07 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - ctgtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20526 JY8QFUQ01B3761 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt 98.14 211/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [1.17.38.11] CARLGPGSGTDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctaCctggagctGggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20527 JY8QFUQ01CYC0M productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-15*01 F 1 8 7 15 8.7.15 [1.17.38.11] CAKMNGWKLQEYNLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 98 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagatatgccatgagctggattcgccaggctccagggaaggggctggagtgggtctcagctattagtaatagtgatgttacatactatgcagactccgttaagggccggttcaccatctccagagacacttcgaagaacacgctgtatctccaattgagcagcctgagagccgaggacacggccgtgtattactgtgcgaaaatgaatgggtggaagttacaggaatacaacttagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcctgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20528 JY8QFUQ01CBHR0 productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20529 JY8QFUQ01A1AYP productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + ctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20530 JY8QFUQ01B3TT1 productive Homsap IGHV1-2*02 F (see comment) 777 84.58 181/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARGLSYDSSPYWGYW in-frame + Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tggatacatcttcaatgacttctacatatattgggtgcgacaggcccctggacaagggcttgagtggatgggatggttcaaccctaatagtcgtgtcacagactatgcagagaaatttcagggcagggtcaccatgaccggggacccgtcccgcagcacagtccacctgaaactgacccgcctgaagtcggacgacacggccgtctattactgcgcgagaggtctctcctatgacagtagtccttattggggctactggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20531 JY8QFUQ01CTR0D productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20532 JY8QFUQ01CC9ZO productive Homsap IGHV4-4*07 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 7 17 8.7.17 [1.17.38.11] CARDSSRSYYEGSGRFDQW in-frame + tctctggtggctccatcaggagtgactcctggacctggatccggcagcccgctgggaagggactggagtggattgggcatactcataccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatgtcagtagacacgtccaagaaccagttctccctgaagttgagctctgtgaccgccgcggacacggccgtctattactgtgcgagagattcaagtcgcagttactatgaaggaagtggtcgttttgatcagtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 20533 JY8QFUQ01ARNM3 unproductive Homsap IGHV1-8*01 F 984 95.79 205/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGGLLRDSIGYSYVPHDH## out-of-frame + tggatacactttcaccagttatgatatcatctgggtgcgacaggccactggacaaggacttgagtggatgggatggatgagccctaacagtggtaacacaggctctgcacagaagttccagggcagagtcaccatgtccagggacacctccataagtacagcctacatggagctgagcagcctgagatctgaggacacggccgtttattactgtgcgagaggcggcttgttacgtgatagtattggttattcttacgtcccgcatgaccactggggcccagggatccctggtcaccgtctcctcaacatcccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 20534 JY8QFUQ01CYAE8 No results 20535 JY8QFUQ01CXWS2 unproductive (see comment) Homsap IGHV3-9*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKRRVGDTSDWYLL*IL# out-of-frame + stop codons cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttagaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccaagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgt 20536 JY8QFUQ01C30IW productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame + cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgaccggtgtcgtggaactc 20537 JY8QFUQ01CO43H unproductive Homsap IGHV3-7*03 F 851 88.07 192/218 nt Homsap IGHJ5*01 F (see comment) 106 66.67 34/51 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CTRRGFMDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggcccaagggaccacggtcaccntctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20538 JY8QFUQ01AQ0OT unproductive Homsap IGHV3-30*01 F 990 95.39 207/217 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CAREPGRGLYTCN##WYFDLW out-of-frame + ctctggattcaccttcagtagccatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtgggggttatatcatctgatggaagtaatgaatactatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactgtatctgcagatgaacagcccgagagctgaggacacggctgtgtattactgtgcgagagagcctgggaggggtttatacacctgcaatgaactggtacttcgatctctggggccgcggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 20539 JY8QFUQ01BQCNP productive (see comment) Homsap IGHV4-61*01 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ3*02 F (see comment) 178 84.0 42/50 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARDGNRGYYSFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagTccccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaacccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggctgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatagaggttattactcttttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactc 20540 JY8QFUQ01B48K0 unproductive (see comment) Homsap IGHV4-61*02 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD5-24*01 ORF 2 10 7 14 10.7.14 [0.17.38.11] CARDFRRFLQF*WPTG in-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctggtgactccatcagtagtgattctcactactggagttggatccggcagcCccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttcggaggttcctacaattttagtggcctactggggccagggaacccttggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 20541 JY8QFUQ01CEEMS productive Homsap IGHV3-48*03 F 797 85.32 186/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CVRQTGDYYFFGLDVW in-frame + cctctggattcgccttcaaaagttttaacatgaattgggtccgccaggcttcagggaaggggccggagtggattgcatacattaatggaagagggactaacatctactatgcagactctgtgaagggccggttcaccatctccagagacaacgcccagaacgcagtgcatctgcagatggaccgcctgagagtcgaggacacggccctatattactgtgtgagacaaactggagactactatttcttcggtctggacgtctggggccaaggaaccacggtcaccgtctcttcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20542 JY8QFUQ01A5IKH productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 7 8 10 7.8.10 [2.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) tgttcgggattcgctttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20543 JY8QFUQ01AO571 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 867 89.72 192/214 nt 89.25 191/214 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGS## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaTggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagcccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20544 JY8QFUQ01BFP3C productive Homsap IGHV3-13*01 F 966 94.86 203/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 20545 JY8QFUQ01ANOJ3 productive (see comment) Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [2.17.38.11] CGTSRSLDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatgggagtgagaAaatactatgtcgactctgtgaagggccgattcaccatctccagagacaacgccgagaactcactacatttgcaaatgaacagcctgagagccgaagacacggctgtgtattactgtgggacgagcaggtcccttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20546 JY8QFUQ01AU066 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F (see comment) 199 89.58 43/48 nt Homsap IGHD3-10*02 F 2 8 7 X 8.7.X [1.17.38.11] CAKESLFGESSHT#FDDW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctgttcggggagtcatctcatacnactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20547 JY8QFUQ01ANXIF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame + gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20548 JY8QFUQ01C183I productive (see comment) Homsap IGHV3-30*15 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARNELPWDTREYYFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaAaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 20549 JY8QFUQ01B6C3B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 845 88.37 190/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.17.38.11] CAREVPHQNIIYLDYW in-frame - ctggattcgactttagcagcgcttccatggcctgggtccgccaggctccagggaaggggctggagtggatctcagctgtcagtggacgtggtgacaacaccttctacgcagcctccgtgaagggccggttcaccatctccagagaccattccaagaacacgctgtggcttcaaatgaacaacctgagagccgaagacacggccctatattactgtgcgagggaagtcccacatcaaaatataatctaccttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20550 JY8QFUQ01DAKJF No results 20551 JY8QFUQ01CII6F productive (see comment) Homsap IGHV3-7*01 F 896 90.37 197/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift); cctctagattcaccTtttaatggttactggatgagttgggtccgccaggctccaggaaaggggGCtgggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20552 JY8QFUQ01A7T6F productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1002 96.73 207/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20553 JY8QFUQ01BYGY7 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20554 JY8QFUQ01BLSOB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccaggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20555 JY8QFUQ01BZ30W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 999 95.85 208/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20556 JY8QFUQ01CDHKA productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.41 198/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'ATTT' (4 nucleotides at position 102 to 105 in the user submitted sequence), (cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaGggggctggagtgggtctcaagtgtcagtagtagtactggttATTTtcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 20557 JY8QFUQ01AU1LL productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARDRRPLREFDCW in-frame - ctctggattcaccctctccagctatgctatgcactgggtccgccagtctcccggcaaggggctagagtgggtggcagctatttcatatgatggaagtaaaatatattacgcagactccgtgaggggccgcttctccatctccagagacagttccaagaacactctgcatttgcaaatggacagcctgagacctgaggacacggctacatattactgtgcgagagatagacggccacttagggagtttgactgttggggccagggaaccccggtcgccgtctcctcggcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 20558 JY8QFUQ01AV820 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20559 JY8QFUQ01BO1PR unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKVV*EP#WYFDLW out-of-frame - stop codons in CDR2-IMGT at codon 62 of V-REGION: 'TT' (2 nucleotides at position 95 to 96 in the user submitted sequence), (cause frameshift); cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggTTtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctaggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20560 JY8QFUQ01CW25E productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20561 JY8QFUQ01C8M8C unknown (see comment) Homsap IGHV3-30*02 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*11 F or Homsap IGHV3-30*12 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-3*02 F or Homsap IGHV3-30-5*02 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 83 86.36 19/22 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found gtctggattccctttcagtaga 20562 JY8QFUQ01C8O8L No results 20563 JY8QFUQ01B7G97 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRGLW*WCMPCR#DYW out-of-frame - stop codons cctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaagggcctggagtgggtctcatccatcagtagtggtggtagtttcaaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcgggggttgtggtaatggtgcatgccatgtcgccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20564 JY8QFUQ01AOUGQ productive Homsap IGHV3-11*01 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + tctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctaagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 20565 JY8QFUQ01B528L productive (see comment) Homsap IGHV3-7*01 F 953 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); tctggattcacatttagtaactactggatgagctgggtccgccaggntcCcagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20566 JY8QFUQ01B20U6 No results 20567 JY8QFUQ01BCXUQ unproductive (see comment) Homsap IGHV3-30*01 F, or Homsap IGHV3-30*05 F or Homsap IGHV3-30*06 F or Homsap IGHV3-30*13 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [2.17.38.11] CAGDLTGGSVLL*Q*WFK#YW out-of-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); caccctctggattcaccttGcagtgaccactacatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgggagatttaactgggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttccccgctgaacctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 20568 JY8QFUQ01DGQF4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 973 94.06 206/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 74 to 74 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctactggatgcactGgggtccgccaagctccagggaagGgggctggtttgGggtctcacgtgttaatggtgatgGggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 20569 JY8QFUQ01BULZ8 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDASRYYYNSYCDN## out-of-frame - ctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20570 JY8QFUQ01BX9B3 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 1009 95.89 210/219 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 2 8 8 20 8.8.20 [2.17.38.11] CVRGDYGGAPGHYYDPYGLDVW in-frame - gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagaggggactacggtggcgcccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20571 JY8QFUQ01CYBYD productive Homsap IGHV3-9*01 F 859 88.89 192/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - tctggattcacttttgatgactctgccatgcactgggtgcggcaagctccagggaagggcccggagtgggtcgcaggtattagtggaaatagtggaaatataggatatgcggactcagtgaagggccgatgcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20572 JY8QFUQ01A455F No results 20573 JY8QFUQ01B2RJO productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.38.11] CATVARRGAFDIW in-frame - tctctggtgggtccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtaacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20574 JY8QFUQ01CGDH8 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 863 89.3 192/215 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-15*01 F 2 8 7 20 8.7.20 [1.17.38.11] CARDPRDYCSGGYCFVGAFDIW in-frame - tctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgatagggactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20575 JY8QFUQ01BNYSV productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20576 JY8QFUQ01B3I3D productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacatactacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20577 JY8QFUQ01CXXGJ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcagtacctataacatgaactgGggtccgccaggctccagGggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactc 20578 JY8QFUQ01CUZ9J productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-15*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARDPRVICSGGSCRSSAMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccagttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagaccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20579 JY8QFUQ01CBOVD unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt Homsap IGHJ5*02 F 174 82.35 42/51 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRQLGFGDLFRFD#PW out-of-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgaccccctggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20580 JY8QFUQ01DDAJF No results 20581 JY8QFUQ01BQYII No results 20582 JY8QFUQ01BY7OB productive (see comment) Homsap IGHV3-30*12 F, or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 3 8 7 13 8.7.13 [1.17.38.11] CASSRDGYNHGLRYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tgtctggattcaccctcagctcctatggcatgcactgggtccgccgggctccaggcaaggggctagagtgggtggcgaatatgtttcatgatggaggctcttactatggaccctccgtgaggggccgattcaccatctccagagacaattcgaagaacacgctatttctacaaatgaacagcctgagagccgaggacacggctctatattactgtgcgagtagtagagatggctacaatcacggcttgagatactggggccagggaaccctggtcaccgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 20583 JY8QFUQ01ABDA1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20584 JY8QFUQ01BODB4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20585 JY8QFUQ01AQGFD unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 83 86.36 19/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggactcagtttcactaa 20586 JY8QFUQ01CXVQF unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 92 90.91 20/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggactcaccttcagtgc 20587 JY8QFUQ01CQ144 productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20588 JY8QFUQ01CC4XP productive Homsap IGHV3-7*01 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20589 JY8QFUQ01CP8K4 productive (see comment) Homsap IGHV4-61*01 F 1100 100.0 221/221 nt 99.55 220/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagAcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20590 JY8QFUQ01B5TJY productive Homsap IGHV3-9*01 F 950 93.12 203/218 nt Homsap IGHJ1*01 F (see comment) 143 75.0 39/52 nt Homsap IGHD4-17*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARLPGDYGSRW in-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaactttgataaatatgacatgcactgggtccgacaagctccagggaagggcctggagtgggtctcaggtattaagtggaatggcggtcgcgtcggctatgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagacctgaggacacggccttctattactgtgcaagactccccggtgactacgggtctcgttggggccagggaaccctcatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20591 JY8QFUQ01CCTXA unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcactttcagtga 20592 JY8QFUQ01BP8CT No results 20593 JY8QFUQ01B2RPV unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 148 91.43 32/35 nt 8 X X 8.X.X [1.2.X.X] null - No rearrangement found ctctggattcacctttagcaactttgccatgacct 20594 JY8QFUQ01BYNMN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-20*01 F 1 8 8 14 8.8.14 [1.17.38.11] CARGLTTMTGNGLEHW in-frame + tctctggattcacccttcgcagatatggcatggcgtgggtccgccaggctccggggaaggggctggagtgggtctcatcttctaacagtagtgatgaatccacatactatgcagactccgtgaagggccgcttcaccatttccagagaccattccaagaacacggtgtttttgcaaatgtacagcctgagagccgaagacacggccctctattactgtgcgagagggctaacaacaatgacagggaatggtcttgagcactggggccagggagccctggtcaccgtctcctcaccatccccgaccagccccaaggtnttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20595 JY8QFUQ01A3B8P productive (see comment) Homsap IGHV4-39*02 F 819 86.24 188/218 nt 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 10 7 19 10.7.19 [1.16.38.11] CARHVVLDNRYSVWPRILDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 74 in the user submitted sequence), (cause frameshift) ctctggtgaccccatcggcaacactgcttactcctggggctggatccgcancccccagggaaTGggggctggagtgatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20596 JY8QFUQ01CRRZO No results 20597 JY8QFUQ01CJDWD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20598 JY8QFUQ01CKWXR productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactCctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatatttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20599 JY8QFUQ01B88H9 No results 20600 JY8QFUQ01ANBGV unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGF*LL# out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cctccgaattcatccttgacagttatgccatgagttgggtccgccaggCccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20601 JY8QFUQ01DH3P5 productive Homsap IGHV3-21*04 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CGKDMRPGGMDVW in-frame + ctctggattcacctttagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaagactactaatgacatatactatgcagactcagtgaagggccgattcaccatctccaaagacaacgccaagaattccctgtatctgcaaatgaacagcctgagagttgaggacacggccatgtattactgtggaaaagatatgcgaccgggcggtatggacgtctggggccagggaatcctggtcaccggtctcctcagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccga 20602 JY8QFUQ01A5J3G productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20603 JY8QFUQ01B3CAL productive Homsap IGHV3-7*01 F 1009 95.89 210/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame - ggctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20604 JY8QFUQ01CLTLS unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 136 55.47 76/137 nt 10 9 X 10.9.X [1.17.8.X] null + No rearrangement found stop codons ctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 20605 JY8QFUQ01AH284 unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 994 93.78 211/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 10 9 14 10.9.14 [1.17.38.11] CARGGDYYDSGGLDYW in-frame + stop codons tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtagtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20606 JY8QFUQ01BDT3E productive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 7 8 11 7.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 37 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) tctctggattcacctttagtaggtttggatgacctgggtccgccagggtccagggaaGggggctggagtgggtggGccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20607 JY8QFUQ01AKYKZ unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 479 82.73 115/139 nt 8 8 X 8.8.X [1.17.12.X] null + No rearrangement found Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacctttaacagccatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcagattctggtggcagtggtcgtaccgcatactacgcagactccgtgacggtgtcgtggaactca 20608 JY8QFUQ01DH3RW unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.58 194/219 nt 88.13 193/219 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKDQSCIVGPCGFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); cctcccgaattcatccttgacagttatgccatgagttgggtccgccaggCccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20609 JY8QFUQ01A96A4 productive Homsap IGHV1-3*01 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20610 JY8QFUQ01A3WY6 unproductive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARGQNGYKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20611 JY8QFUQ01BWLVQ unproductive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F 953 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD6-13*01 F 1 8 8 X 8.8.X [1.17.37.11] CAKDAMGGAGDWAAFWYL# out-of-frame + in FR3-IMGT, from codon 99 of V-REGION: 2 nucleotides (from position 200 in the user submitted sequence), (cause frameshift) ctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaagacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgctttttggtatctggggccaggggacaattggtcactgtctcttcagccatccccgactcgccccaaggtcttccccgtgagccctccgagcaccccccaaagatgggaacgtggtccgtcgcatgcctggtccagggcttcttccccca 20612 JY8QFUQ01BBV1G productive (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P (see comment) 953 93.95 202/215 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGPHQYYFDYW in-frame + however the closest V is a pseudogene The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (8 AA in JY8QFUQ01BBV1G ; 7 AA in Homsap_IGHV3-69-1*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccggttcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaaggtccgcatcaatactactttgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20613 JY8QFUQ01CEON4 productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + cctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20614 JY8QFUQ01BQF91 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 56 to 57 in the user submitted sequence), (cause frameshift); ctctggattctccgtcagtAagttactggatgcactgggtccgccaggctccaggGGgagggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagattactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 20615 JY8QFUQ01C35W7 unproductive (see comment) Homsap IGHV3-7*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons cctctggattcacctttagtaaccattggatgaactgggtccgccaagctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20616 JY8QFUQ01DBTFY No results 20617 JY8QFUQ01DNQJ0 unproductive Homsap IGHV4-39*07 F (see comment) 789 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 1 9 7 X 9.7.X [2.17.38.11] CARAVLDNAWPIYYDFW# out-of-frame + Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 35 in the user submitted sequence), (cause frameshift) gtgtctggtggctccatcaccacttggcattactgggggctggatccgccagcccccaggggagggtctggaatggattggaaatgtctatcataatggcaatatcgcctatagcccgtcgcagaggagtcgaatcaccatatcagtagacacgtccaggaaccagttctccctgaagatgacctctgtgaccgccgcggacacggctgtctattactgtgcgagggctgttcttgacaatgcctggcctatatattatgacttttgggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 20618 JY8QFUQ01B69TS No results 20619 JY8QFUQ01BASRH productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 895 90.74 196/216 nt 89.81 194/216 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-15*01 F 3 8 7 15 8.7.15 [2.17.38.11] CTRELRVAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcctctggattcaccgtcagtaccaaGgttcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcagtaatttatcctgatggtactacacactatggagcctccgtgaggggccggttcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttcgggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20620 JY8QFUQ01CS2E5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'C' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccCgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20621 JY8QFUQ01AYHYC productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20622 JY8QFUQ01AZTNG productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1110 100.0 223/223 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD4-17*01 F 3 8 10 12 8.10.12 [1.17.38.11] CTKCSVTIYFLTTG in-frame + ttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttactttttgactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaactc 20623 JY8QFUQ01A0C33 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); tctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagccctccaccaagggcccatcggtcttccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20624 JY8QFUQ01DKHHD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 952 94.37 201/213 nt 93.43 199/213 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 7 8 12 7.8.12 [0.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 49 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift) ctacattcgcctttagcactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20625 JY8QFUQ01A4LK9 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 804 84.75 189/223 nt 82.51 184/223 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,75% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GA' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'GG' (2 nucleotides at position 81 to 82 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); tgtctctggtgactccatcagtagtactcattactattGggggctggatccggcagccccccagggaggggGActggagtGGggttggggagtatCccactacactgGggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc 20626 JY8QFUQ01ASRUM unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 20627 JY8QFUQ01CDK3J productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20628 JY8QFUQ01CJF57 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 734 82.11 179/218 nt Homsap IGHJ3*01 F (see comment) 205 90.0 45/50 nt Homsap IGHD3-3*02 F 2 8 8 13 8.8.13 [1.17.38.11] CARIWDSWSGAFDVW in-frame - Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*01 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) cctctggattcccctttagtgtgtactggatgtactgggtccgccaaagtcccgggaaggggccggtatgggtcgcacgtatcagtgatgatggcaagagtatcagttatgcggactccgtaaggggccgattcaccatctctagggacaacgcccagaacacactgtctctgcaaatggacaatgtgagagccgacgactcgtctgtctattattgtgcaagaatttgggattcctggagtggagcttttgatgtgtggggccaagggacattggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20629 JY8QFUQ01CIIBR unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [2.17.38.11] CAEKNIIIRGLI#YNFDYW out-of-frame - gcctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcggaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20630 JY8QFUQ01B1I83 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 8 12 8.8.12 [1.17.38.11] CVREGAATGSFYYW in-frame - ctctggcattcaccttcagtgactatgccatgagctgggtccgccaggctccagcgaaggggctggaatgggtctcagcgattagcagtagtggtgatagaacatactacgcagactccgtgaagggccgattcaccatctccagagacagttccagggggactctgtatttgcaaatgaaccgcctgagcgccgaggacacggccctatatttctgtgtgagagaaggagcagcaactggttcgttttactactggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcacgcctgcctggtccagggcttcttccccca 20631 JY8QFUQ01B1ZKV No results 20632 JY8QFUQ01CDJ94 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt 99.53 214/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttactactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 20633 JY8QFUQ01B3G22 productive Homsap IGHV3-7*02 F 904 91.2 197/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - tctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaaggggcccatcggtnttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20634 JY8QFUQ01CIVFH No results 20635 JY8QFUQ01A6R3G No results 20636 JY8QFUQ01BPJ86 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 836 87.5 189/216 nt 86.57 187/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); tctggattcagcctcaCtttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccntgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacctTgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20637 JY8QFUQ01BAEEF unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtaaatataccatgaaatgggtccgccaggctccagggaaggGggctggagtgggtctcatccatcagtagtagtagtggttacatatactactcagattcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20638 JY8QFUQ01AXH9R unproductive (see comment) Homsap IGHV1-18*01 F (see comment) 743 83.81 176/210 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-21*02 F 3 7 8 17 7.8.17 [X.17.38.11] CVREESIVVVTGRRGMDVW in-frame - stop codons Low V-REGION identity (83,81% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ggttagttntacacctctgtgttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagcacagcctacatggagctgaggagcctgagatctgacgacacggccatgtattattgtgttagagaagagtcaattgtggtggtgaccgggcggcggggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20639 JY8QFUQ01CMW48 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARHGSGWLQELDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcatcagagacagtgcctactGggggctggatccgccagcccccagggaaggggctggagtggcttgggagcatctattatagtgggagtacctactacaatccctccctcaagagtcgagtcaccatatccgtagacacgtccaagaagcagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcgagacatggcagtggctggctccaggaacttgactactggggccagggaaccctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20640 JY8QFUQ01BY1FZ productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.16.38.11] CARLPNTIDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 77 in the user submitted sequence), (cause frameshift) ttctggatatagttttgccacctactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccgggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgaaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20641 JY8QFUQ01CFAIY productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 909 91.24 198/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD1-1*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKVSGNSRTYWYLDIW in-frame + ttctggatacaactttcccagatattggatcgcctgggtgcgccagattcccgggagaggcctggagtgggtggggatgatctatcctggtgactctgagaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacgcgtccatgaacaccgcctacctgcagtggagcagcctgaaggcctccgacaccgccatatacttctgtgcgaaggtctctggtaactctcgaacctactggtacctcgatatctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggttcagggcttcttccc 20642 JY8QFUQ01CXWBJ productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 973 94.06 206/219 nt 93.15 204/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'GC' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggGCaagggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccAaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctctaggagcacctccgagagcacacgcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggctgtcgtggaact 20643 JY8QFUQ01ADDA1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20644 JY8QFUQ01BC8WA No results 20645 JY8QFUQ01AG7C2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV## out-of-frame - tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaagggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20646 JY8QFUQ01BIWAX No results 20647 JY8QFUQ01ADG4G unproductive Homsap IGHV3-30*01 F 874 89.04 195/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20648 JY8QFUQ01DC3JM unproductive Homsap IGHV3-7*02 F (see comment) 734 82.11 179/218 nt 81.65 178/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARLKGPDTS##FYFDLW out-of-frame + Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'AGG' (3 nucleotides at position 60 to 62 in the user submitted sequence), (do not cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacaggggaaAGGgggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggcctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 20649 JY8QFUQ01ASHCC productive (see comment) Homsap IGHV3-11*01 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-2*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPYCSSTNCYPYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaaggggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20650 JY8QFUQ01A4T8J unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 769 83.8 181/216 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20651 JY8QFUQ01AZKRJ productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20652 JY8QFUQ01BO2MF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 990 95.39 207/217 nt 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARDNYGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20653 JY8QFUQ01BYBLN No results 20654 JY8QFUQ01CUOJE unproductive Homsap IGHV3-7*01 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKARIYFYGSGSYSLFDY## out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'GC' (2 nucleotides at position 128 to 129 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctcccgggaaggtgctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggGCccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20655 JY8QFUQ01CE09T unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null - No rearrangement found cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20656 JY8QFUQ01DSA5W productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'GT' (2 nucleotides at position 9 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'TG' (2 nucleotides at position 95 to 96 in the user submitted sequence), (cause frameshift); cctctggaGTtcagccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatTGgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20657 JY8QFUQ01CN0FC productive Homsap IGHV4-61*02 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSAPWNDHW in-frame + tctctggtggctccatcagcagcggttattactactggagctggatccggcagcccgccggggagggactggagtgggttgggcgtatctctgccagtggggacaccaactacaacccctccctcaagagtcgagtcaccatatcagtgaacacgtccaagaaccagttctccttgaggctgacctctgtgaccgccgcagacacggccgtgtattactgtgcgagacaaggggacagtagtgctccctggaatgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20658 JY8QFUQ01ADKPR unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 20659 JY8QFUQ01B3CG7 productive Homsap IGHV4-61*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + ctctggtggctccgtcaacagtggtaatttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20660 JY8QFUQ01B315R productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggaccggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20661 JY8QFUQ01COL8E productive Homsap IGHV4-61*01 F 1100 100.0 221/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 10 7 20 10.7.20 [1.17.38.11] CARVSGYAYGRYGDYLRGVDYW in-frame - tctctggtggctccgtcagcagtggtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagggttagtggctacgcgtacggacgctacggtgactatttgcgcggggttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20662 JY8QFUQ01BZNNC unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 752 83.03 181/218 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD2-8*02 F 2 8 7 X 8.7.X [2.17.38.11] CAGEEMRTRDGGW#YGTDVW out-of-frame - Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctctgggtgggctccatgactctttattattggagttggatccggcagcccgcagggaaggggctggagtgggttgggtacatcgatcacgctgggagcgccaagtataacgcctcccttcagagtcgagtcaccatctcagtcgacgcgcccaagaatcagttctctctgaagttgaactctgtgactgctgcggacacggccgtttattactgtgcgggagaagagatgcgaacgcgggacggggggtggctacggaacggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20663 JY8QFUQ01A6I3L productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 3 8 8 10 8.8.10 [1.17.38.11] CANELGYCSGGG in-frame + ctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20664 JY8QFUQ01CG00S unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1045 97.72 214/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKSGVGAT#YFDYW out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'TA' (2 nucleotides at position 19 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); gcctctggattcacatttTAggcagctatgccatgAagctgggtccgccaggctccagggaaTGgggcttggagtgggtctcagctattagtggtagtggtggtggcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagtcaggggtgggagctacaactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20665 JY8QFUQ01B1UHR productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtagctactggatgGcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtactaatacgggggggactagcacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20666 JY8QFUQ01AOYON unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F 896 89.95 197/219 nt 89.04 195/219 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 10 6 X 10.6.X [1.17.38.X] null - stop codons no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 44 of V-REGION: 'CA' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) ctctggtgactccatgagcggtagtagtgactcctgggactggatccggcCAgtcccccagggaaggggctggagtggattgggagcacnattctagtggggccacttactacagcccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaagcaattctccctgaaactgacctctgtgaccgccgcagacacggcggtgtattactgtgcgagacatctgatttactactttcacttctgggggccagggaacccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20667 JY8QFUQ01ABCV4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20668 JY8QFUQ01A6L65 productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcagg 20669 JY8QFUQ01BPIG0 No results 20670 JY8QFUQ01BUZWP unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CACYFR**WF#FDYW out-of-frame + stop codons ttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgcccggtaaaggcctggagtggctgggaaccatctatcccggcgactctgacaccacatacagcccgtcattccaaggccaggtcaccatgtcagtcgacacgtccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttcgatagtaatggtttctttgactactggggccagggaaccccaggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccttggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20671 JY8QFUQ01ALCBS productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 996 95.0 209/220 nt 94.09 207/220 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 9 7 14 9.7.14 [2.17.38.11] CARGEMTAEYYFDYWG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcagcagtgttCaactggtggagttgggtccgccagcccccagggaaggggctggagtggaTttggggagatctctcacagtgggaacaccaactacagcccgtccctcaagggtcgagtcaccatatcaataaacaagtccaagaaccaattctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagaggggaaatgactgccgagtactactttgattactgggggccagggaagcccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 20672 JY8QFUQ01A4LR9 productive (see comment) Homsap IGHV4-61*02 F 987 94.55 208/220 nt 93.64 206/220 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 10 7 11 10.7.11 [1.17.37.11] CATVARRGAFDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) tctctggtgggtGccatcagcagtactagttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaacccctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgaccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20673 JY8QFUQ01DIK16 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 967 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtCagtgactggatgtactgggtccgccaagctccagggaaggGggctggtntgggtctcacgtattaatggtaatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20674 JY8QFUQ01DGHAU productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 854 88.84 191/215 nt 88.37 190/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 2 8 7 19 8.7.19 [1.17.38.11] CARSSDYLWGSYRYPYYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagttacttctggagttggatccggcagcCccccagggaagggactggagtggattggatatgtctattacagtggaagtaccaagtataatccttccctcgaaagtcgagtcaccatatcattagacacgcccaacaaccagttctccctgagcctgacctatgtcaccgctgcggacacggccatatactactgtgcgagaagctctgattacctttgggggagttatcgttatccctactacttcgactactggagccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20675 JY8QFUQ01BKOTH productive Homsap IGHV4-30-2*02 F, or Homsap IGHV4-55*06 P or Homsap IGHV4-59*01 F or Homsap IGHV4-59*02 F or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F or Homsap IGHV4-59*09 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*07 F or Homsap IGHV4-61*08 F 162 94.59 35/37 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*02 F 2 X X 12 X.X.12 [X.X.12.11] CARAPGWMNPFDFW in-frame - ctccgtgaccgttgcggacacggccgtgtattactgtgcgcgcgccccagggtggatgaatccctttgacttctggggccagggcactctggtcaccgtctcctcggcatccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20676 JY8QFUQ01BK2YW No results 20677 JY8QFUQ01AOV8Y unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDCDSGECNFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctctggattcagcttcagtacctataacatgaactgggcccgccaggctccagGggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20678 JY8QFUQ01B9DAH productive Homsap IGHV4-4*07 F (see comment) 862 89.67 191/213 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-22*01 F 2 10 7 22 10.7.22 [1.17.38.11] CARERAYDRNGFYYANRHNWLDTW in-frame - The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (10 AA in JY8QFUQ01B9DAH ; 8 AA in Homsap_IGHV4-4*07) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggtgcctccatcacatttggcagttactactggaattggatccggcagcccgccgggaagggactggagtgggtaggacgtatctatgcaagtgggaccacccattccaacccctctctcgagactcgagtcatcatgtcactagacacgtccaacaaccagatctccctgaagctgacctctgtgaccgccgcggacacggccgtgtattactgtgcgagagaaagggcctatgatagaaatggcttttactacgcgaaccgccacaactggctggacacctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20679 JY8QFUQ01BYDJU No results 20680 JY8QFUQ01A939N unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CAGHLLGDP#FDYW out-of-frame - stop codons in FR3-IMGT at codon 67 of V-REGION: 'C' (1 nucleotides at position 107 to 107 in the user submitted sequence), (cause frameshift); ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatctcggtgactctgacaccagaCtacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgaccctttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20681 JY8QFUQ01BU2ZW productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaactca 20682 JY8QFUQ01CSC73 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20683 JY8QFUQ01AFH8P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20684 JY8QFUQ01BPW7W unknown (see comment) Homsap IGHV4-4*08 F 146 53.71 94/175 nt 8 7 X 8.7.X [9.17.17.X] null - No rearrangement found stop codons gaccctgtccctcacctgcgatgtctctggtggctccatgactggttactactggagttggatccggcggccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 20685 JY8QFUQ01BWMMI productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 794 84.62 187/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 10 15 8.10.15 [1.16.38.11] CTTDSFHIAVHGVFDFW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 32 in the user submitted sequence), (cause frameshift) tctgcattcatgttcaacaaagcctggatgaattggtccgccaggctccaggAaaagggactggagtgggttggccgtattaaaagtaacggcgacggtgcgacagtcgactacgctgcacCccgtgaaaggccgattcaccatctcaagagatgattcacagaataccctcttcttacaaatgagcagcctgaaagccgaggacacagccgtctattattgtaccacagatagcttccatattgcagtgcatggcgtctttgacttctggggccagggagccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcctcttccccca 20686 JY8QFUQ01AF4Q3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDYGDCRGGRCYAEPLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); catctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggaaaggGggctggagtgggtctcaggtattagtgatcatggtattgacatatactatgcagactccgtgaggggccggtttaccatctccagagacatttccaagaacacggtgtatctacaaatgaacagcctgggagtcgaggacacggccgtatattactgtgcgaaagattacggggactgtcgtggtggtagatgctacgccgagcccctcgactactggggccagggaaccctggtcacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcancgcctgcctggtccagggcttcttccc 20687 JY8QFUQ01DM0CT No results 20688 JY8QFUQ01BWLFO No results 20689 JY8QFUQ01ABKIU No results 20690 JY8QFUQ01C02DF No results 20691 JY8QFUQ01B6PUH productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-48*04 F 621 99.21 126/127 nt 98.43 125/127 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 X 22 8.X.22 [1.6.26.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 91 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20692 JY8QFUQ01BBB3H productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20693 JY8QFUQ01CNCGL unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 101 95.45 21/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttaagtga 20694 JY8QFUQ01AVX5J unproductive (see comment) Homsap IGHV4-61*01 F 983 94.12 208/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 X 10.7.X [1.17.38.11] CARGGPVGPTGI*SG#W out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 111 to 122 in the user submitted sequence), (do not cause frameshift); tctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 20695 JY8QFUQ01BFYAE productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDVTSESHFFALDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcatttcttcgctttggacgtctggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20696 JY8QFUQ01CGUXU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 859 88.89 192/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20697 JY8QFUQ01DA1JV unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F 869 88.99 194/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [1.17.38.11] CAREHDTGVATRYFDY## out-of-frame + in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); cctctggattcgccttcagtctgtatcctatgcactggGgtccgccaggctccaggcaaggggActagagtgggtggGcacttatctcctctgatggaagtgataagttttcctcagactccgtgaagggccgattcgccatctccagagacaattccaagaacacggtctatctacaagtggacagcctgagaactgaggacacggctatgtatttctgtgcgagagagcacgacacgggagtggcgacgaggtattttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 20698 JY8QFUQ01AKKV6 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame + cctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20699 JY8QFUQ01B1B92 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtaactatgacatgggctGgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20700 JY8QFUQ01BO2CM productive Homsap IGHV3-33*04 F (see comment) 698 80.28 175/218 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.17.38.11] CARDILDYW in-frame - Low V-REGION identity (80,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release catttggattccctttcagcgactatggcatgcactgggtccgccagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20701 JY8QFUQ01CQKI9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-25*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDLLGIAPAGHSLDHW in-frame + ctctggattcacctttggcaactatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagaggtgaccacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacactgtttctgcaaatgaatagcctgggagtcgaggacacgaccgtatattactgtgcgaaggatcttctagggattgcgccggcgggccattcccttgaccactggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20702 JY8QFUQ01AFCWF productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20703 JY8QFUQ01C28XA productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 967 94.44 204/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame - ctggagtacagttttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20704 JY8QFUQ01BCVP2 productive (see comment) Homsap IGHV4-61*01 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGAYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 112 to 123 in the user submitted sequence), (do not cause frameshift); gtctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20705 JY8QFUQ01AR7B6 productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame + cctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20706 JY8QFUQ01CPGWX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARGHSYYVSSGPDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 114 to 114 in the user submitted sequence), (cause frameshift); agcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgCcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20707 JY8QFUQ01CPE55 productive (see comment) Homsap IGHV4-4*07 F (see comment) 750 83.64 179/214 nt 82.24 176/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'GCGT' (4 nucleotides at position 79 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'CT' (2 nucleotides at position 213 to 214 in the user submitted sequence), (cause frameshift); ctctggtacctccatcagcacttactattggagttCggttccggcagcccgccgagaagggactggagtggaattgggGCGTatctctgtctttgcaaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCTtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20708 JY8QFUQ01ABP0U productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame - tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20709 JY8QFUQ01B6VRF No results 20710 JY8QFUQ01ALKG8 No results 20711 JY8QFUQ01DPIF7 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDSRHSASGSYSDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactgggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20712 JY8QFUQ01AB9MS productive (see comment) Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggGggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20713 JY8QFUQ01C4HVK productive (see comment) Homsap IGHV3-66*02 F 894 91.12 195/214 nt 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtagcagcttcatgacttGgggtccgcctggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact 20714 JY8QFUQ01ALAOB productive (see comment) Homsap IGHV1-3*01 F 858 89.25 191/214 nt 88.79 190/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-8*02 F 2 8 8 13 8.8.13 [0.17.38.11] CARDGYLPGNGADFW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); tggatacaGccttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcatcgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20715 JY8QFUQ01CV8HV unproductive Homsap IGHV1-2*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDGISMTLVRGVRPFDY## out-of-frame + tggatacaccttcatcggccattatatacattgggtgcgacaggcccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactgggggccagggaaccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 20716 JY8QFUQ01BRNII productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 803 85.07 188/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtctctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaac 20717 JY8QFUQ01BOFAK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20718 JY8QFUQ01AYAP4 productive (see comment) Homsap IGHV3-7*01 F 933 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [2.17.38.11] CARGSYWHYDTFGDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'AA' (2 nucleotides at position 85 to 86 in the user submitted sequence), (cause frameshift); agcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacatAAaaatcaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 20719 JY8QFUQ01B6H5N productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaaggacccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20720 JY8QFUQ01AGHGS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F 992 94.57 209/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-6*01 F 3 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEYW in-frame + tctctggtgactccatcagcagtagttcttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctttcatagagggagcacctactccaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccttttctccctgaatctgagctctgtgaccgccacagacacggctgtttattactgtgcgagacattcgagactcgtccgttactttgaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20721 JY8QFUQ01DG6CB productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 145 78.72 37/47 nt 8 8 5 8.8.5 [1.17.38.11] CAHTAFW in-frame - ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaatcccataaacactctttttctgcaaatgaacagcctcagagtcgaagattcgggtgtctatttttgtgcacacactgccttctggggccggggatcccgggtcaccgtctcctccgcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20722 JY8QFUQ01AA7HK unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 876 90.19 193/214 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - aggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20723 JY8QFUQ01CKO8I productive (see comment) Homsap IGHV4-4*07 F 1061 99.53 214/215 nt 98.6 212/215 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD4-11*01 ORF 2 8 7 13 8.7.13 [1.17.38.11] CARDFSNRGWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagtttctactggagctggatccggcagcccgccgggaagggactggagtggattggGgcgtatctataccagtgGggagcaccaactacaacccctccctcaagagtcgagtcaccatgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagacttcagtaacagaggatggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 20724 JY8QFUQ01B63YT No results 20725 JY8QFUQ01BYXTT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20726 JY8QFUQ01A7TR1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20727 JY8QFUQ01BJY9W No results 20728 JY8QFUQ01B2LLS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 828 87.1 189/217 nt Homsap IGHJ2*01 F (see comment) 130 71.7 38/53 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVKEDHDSGLRVLLEW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggagggggctggagtgggtcgcaagcatgggtaatagtgctggcagtacatactacgcaggctccgtgaagggtcgcttcaacatctccagagacaattccaagaaaaccctgtatcttcaaatggacagcctgagagtcgacgacacggccagatattactgtgtgaaagaagaccatgattcgggcctcagggtcctccttgagtggggccggggaaccctggtgactgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20729 JY8QFUQ01CEEBP No results 20730 JY8QFUQ01A990T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame - ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20731 JY8QFUQ01B9QX0 productive (see comment) Homsap IGHV3-7*01 F 1021 97.22 210/216 nt 96.76 209/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtactattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20732 JY8QFUQ01B63RG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 196 76.47 52/68 nt 8 X X 8.X.X [1.13.X.X] null - No rearrangement found gctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggcttcttccccca 20733 JY8QFUQ01B9IRL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20734 JY8QFUQ01AAS9C productive Homsap IGHV2-5*02 F 1134 96.31 235/244 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gaccctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcattttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20735 JY8QFUQ01B8O0E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20736 JY8QFUQ01ABTRQ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 775 85.71 180/210 nt 85.24 179/210 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD1-26*01 F 2 7 8 X 7.8.X [X.17.38.11] CATRNKMGISTPVDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); ctcaacattggcaactatgacatgacctgggtccgccaggctcctgggaaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccggttcaccatctccagagacaactcccagactacgctgTtttttggagatgagcagcctgagagacgaggacacggccgtatattactgtgcgacaaggaataaaatgggaattagtacgcctgttgactactgggggccagggaaccctagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20737 JY8QFUQ01DNAB2 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 853 86.94 193/222 nt 86.49 192/222 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift); tctggattcaCcatttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggttggccgtattaaaaaggcagttgatggtgggccaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcaaaaaatacgttgtatttgcaaatgaacagcctgaaaagcgacgacacaggcatttattactgcacctcgaattcctggctcgaccgctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20738 JY8QFUQ01BQJ6P No results 20739 JY8QFUQ01BX764 productive (see comment) Homsap IGHV1-2*02 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDWGGKYAPLDNW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'A' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctggatacatcttcaccggctactatttgcactgggtgcgacaggAcccctggacAaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccatcagtacagcctacatggaactgaacaggctgatgtctgacgacacggccatgttttactgtgcgagagattggggtgggaagtacgcaccgctagacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20740 JY8QFUQ01A8FGD productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 133 74.0 37/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20741 JY8QFUQ01CGUYG productive Homsap IGHV3-72*01 F 971 92.86 208/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20742 JY8QFUQ01CECEB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 777 85.05 182/214 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-13*01 F 1 8 8 14 8.8.14 [0.17.38.11] CARDAGNTWPNYFDHW in-frame - tggattcagctttttcaattatggcatgaactgggtccgccaggctccagggagggggctggagtgggtcgcatttattagcggtgctggtgaaaatacttactacgcagactccgtgaagggccgattcgccatctccagagacgattcgagggacacactgtatctccaaatgagcagcctgagagccgaggactcggccctctattattgtgcgcgagatgcgggcaacacctggcccaactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20743 JY8QFUQ01C2XVI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 897 90.0 198/220 nt 89.55 197/220 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [2.17.38.11] CVSDLAGQKGS## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); agcctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaAaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggaagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagctctgcagcaccacgccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20744 JY8QFUQ01BF03M No results 20745 JY8QFUQ01APHY3 unknown (see comment) Homsap IGHV1-2*02 F (see comment) 777 84.58 181/214 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tggatacatcttcaccggctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccatcagtacagcctacatggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20746 JY8QFUQ01CB4YK No results 20747 JY8QFUQ01AXR1M productive (see comment) Homsap IGHV3-48*01 F (see comment) 754 84.04 179/213 nt 82.63 176/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CSRDGRRGYDLDSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 82 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcggGaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtGgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20748 JY8QFUQ01BIE6S productive (see comment) Homsap IGHV3-7*02 F 860 88.07 192/218 nt 86.24 188/218 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CVVSSGWLFHYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'TG' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'AG' (2 nucleotides at position 130 to 131 in the user submitted sequence), (cause frameshift); cctctggattcacctctcctagatactggatgaattgggtccgccaggcttccggggaagGGggctggagtggggTGgccaaacataaagcaagacggaagtgagGaaaaactttgtggactctgtgaaAGgggccggttcaccatctccagagacagcgccaagaattcaatgtctctacaaatgaacagcctgagagtcgaggacacggctgtatattattgcgttgttagcagtggctggttgttccactactggggccagggctcccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20749 JY8QFUQ01AZRH6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20750 JY8QFUQ01BBRQO No results 20751 JY8QFUQ01BV511 unknown (see comment) Homsap IGHV3-71*03 P, or Homsap IGHV3-73*01 F or Homsap IGHV3-73*02 F 92 90.91 20/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggtttcacgttcagtgg 20752 JY8QFUQ01BVVPS productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CVRGRIVSVGMAGWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); tctctggattcaccttcagGgaactattggatgcactgggtccgccaagctccagggaaggGggctggagtgggtctcacgtatcaatggcgacggaagtagcacaagctacgcggactccgtgaagggccgattcaccatctccagagacaacgccgagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacagccgtatatttttgtgtaagaggccgtatagtgtcagttggtatggcaggctggttcgacccctggggccagggaacgcaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20753 JY8QFUQ01DLFRL No results 20754 JY8QFUQ01BT0O2 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtaattactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtttctgcaaatgaacagtctcagagtcgaggacacggctgtttattactgtacaagagacatcggtgggcgctactcctactggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20755 JY8QFUQ01DP6L3 productive (see comment) Homsap IGHV3-7*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 12 in the user submitted sequence), (cause frameshift) cctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20756 JY8QFUQ01AL2JX unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARKRVPGGDFLW#DYW out-of-frame + ctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccgggggggactttttatgggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20757 JY8QFUQ01AMN6K productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 860 88.53 193/218 nt 87.61 191/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-23*01 ORF 1 8 8 10 8.8.10 [1.17.38.11] CARLGQLALDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'CG' (2 nucleotides at position 99 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); gttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaagggcctggagttgatgggaatcatctttcctggtgactctCGaggcccagatacagcccgtccttccCaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactggggcgagggaaccctgatttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20758 JY8QFUQ01CHCOL productive Homsap IGHV1-8*01 F 912 92.06 197/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [0.17.38.11] CAREGLLGSLGSW in-frame - aggatacaccttcatcagttatgatatcaattgggtgcgacaggccactggacaagggcttgagtggatgggatggatgaaccctaacagcggtaacacagggtttgcacagaggttccagggcagagtaaccatgaccaggaacatctccataaacacggcctacatggagctgaccaacctgacatctgatgacacggccgtatattattgtgcgagagaaggtctattgggcagcctaggatcttggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20759 JY8QFUQ01CMO81 No results 20760 JY8QFUQ01AYINE productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20761 JY8QFUQ01B7FDU unknown (see comment) Homsap IGHV3-43*02 F, or Homsap IGHV3-43D*01 F 129 62.82 49/78 nt 8 X X 8.X.X [1.17.X.X] null - No rearrangement found tctggattcacgtttgatgactatggcatgcactgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20762 JY8QFUQ01CJS0O productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-25*01 F 2 8 7 15 8.7.15 [1.17.37.11] CTRELRMAAARDGVDIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 203 in the user submitted sequence), (cause frameshift) cctctgggttcgccgtcagtagcaagttcatgagttgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatcctgatgggactacacactatggagactccgtgaggggccgattcaccacctccagagacaattctaagaacatcttggatcttcaaatgaacagcctgagagccgaggacacggcgttacttattgtacgagagaacttaggatggctgcggcgcgtgatggtgttgacatctggggccaaggcacaatggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20763 JY8QFUQ01BCFRZ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); ctctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggGtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20764 JY8QFUQ01B44NZ No results 20765 JY8QFUQ01A9TKS No results 20766 JY8QFUQ01CBZJD No results 20767 JY8QFUQ01DICV1 productive (see comment) Homsap IGHV3-7*01 F 1035 97.7 212/217 nt 97.24 211/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); ctctggattcaggtttagcatctattGggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20768 JY8QFUQ01DEEMH unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 150 56.52 78/138 nt 10 7 X 10.7.X [1.17.10.X] null + No rearrangement found stop codons tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 20769 JY8QFUQ01AQXYS No results 20770 JY8QFUQ01CSABC productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtccgtggaactcag 20771 JY8QFUQ01AN7G1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 918 91.71 199/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactggatccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20772 JY8QFUQ01DPW4S No results 20773 JY8QFUQ01BAHK0 productive Homsap IGHV3-74*03 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRDSDSSASYFAHW in-frame + gcctctggattcaccttcagtagctactggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 20774 JY8QFUQ01AIINB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-33*02 F or Homsap IGHV3-53*01 F or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F (see comment) 290 78.95 75/95 nt 77.89 74/95 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 X X 12 X.X.12 [X.X.31.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (78,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 84 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); tgtctggattcaccatctccagagacaattccaGgggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20775 JY8QFUQ01DQG8Q unproductive Homsap IGHV4-61*02 F 907 90.09 200/222 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD2-21*01 F 3 10 7 X 10.7.X [2.17.38.11] CAREKGSDPS#NWFDPW out-of-frame + gtctctggtgactccatcaccagtggtagttattattggagttggatccggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggagcaccaactacaatccctccctcaagagtcgagtcaccatagtattagacacgatcaacaaccggttctccctgcagctcaggtctgtgaccgccgcagacacggccgtatattactgtgcgagagaaaaaggtagtgatccgtcccaactggttcgacccctggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20776 JY8QFUQ01A0WDV productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20777 JY8QFUQ01COIIN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20778 JY8QFUQ01AD6S1 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 169 76.27 45/59 nt 8 X X 8.X.X [1.10.X.X] null + No rearrangement found ctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca 20779 JY8QFUQ01AOP21 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggGggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20780 JY8QFUQ01DIP8G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAKEIAVSGEGALDFW in-frame + gcctctggattcaccttcagtaactatagcatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctttcccca 20781 JY8QFUQ01BTQ4G unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 810 94.44 170/180 nt 8 8 X 8.8.X [2.17.25.X] null + No rearrangement found gcctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatg 20782 JY8QFUQ01CK6Q5 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame - Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20783 JY8QFUQ01APDWZ No results 20784 JY8QFUQ01A4XDT productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 99.54 216/217 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagGggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20785 JY8QFUQ01AUC9Z productive Homsap IGHV3-9*01 F 994 95.83 207/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD1-7*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDKWNSPLYFFDYW in-frame + tctggattcagttttgatgattatgccatgcactgggtccggcaagttccagggaagggcctggagtggctctcagggatcagttggaatagtgggagcaaaggctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagctgaggacacggccttttattactgtgcaaaagataagtggaactcccccctctacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 20786 JY8QFUQ01CHR57 unproductive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQVTEDY# out-of-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggccagggaaccctggtcagtgtctcctccagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20787 JY8QFUQ01B6VLM productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20788 JY8QFUQ01B3AX2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-9*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVREGIEYYEISTGQYYYDMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); cctctggattcacAttttagcggctatggcatgagctgggtccgccaggctgcagggaaggggctggaatgggtctcatttattagtggtaagagcggcaacatatactatgcagaccccgtgaagggccggttcaccatctccagagacaactccaagaataggctcttcctgcagatgaacagcctgagagtcgaggacacggccaaatattactgtgtgagagagggcatagagtattacgaaatctcgactggacagtactactacgatatggacgtctggggccaggggaccacggtcaccgtcctctctgcatcccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20789 JY8QFUQ01CYMCX productive Homsap IGHV3-48*01 F 864 88.94 193/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + ctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20790 JY8QFUQ01A9YO5 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARQRYYESDGQTW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaccggaagtagttattattggggctggattcgccagTcccccagggaaggggctggagtggattggaagtatgtattacactgggagcaccgactacaacccgtccctcaagagtcgggtcacgatatccgcagacaagtcgaagagccaggtctacctgaagttggactctgtgaccgccgcagacacaggtgtttattactgcgcgagacaaaggtactatgaaagtgatggccaaacctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20791 JY8QFUQ01BNISQ productive Homsap IGHV4-4*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 160 80.0 40/50 nt Homsap IGHD3-22*01 F 2 8 7 11 8.7.11 [1.17.38.11] CAGRNGNLAFNIW in-frame - tatctggtggttcgatcgtcagttactactggagttggatccggcagtccgccgggaagggactggagtggattgggcgcatctactccaatggagatacgagctacaatccctccctcaagggtcgagtcaccatgtcagtagacccttccaacaaccagttctccctgaaattgacttctgtgaccgccgcggacacggccatatattactgtgcgggaagaaatggaaatttggccttcaatatttggggccaagggacaaatgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20792 JY8QFUQ01BFOH6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20793 JY8QFUQ01CDUMU unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 394 75.71 106/140 nt 8 8 X 8.8.X [2.17.11.X] null - No rearrangement found Low V-REGION identity (75,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttagtgcctacgccatgagctgggtccgccaggctccggggaaggggctggagtgggtctcaggcatcactgatggtgatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20794 JY8QFUQ01B1UM4 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F (see comment) 644 77.06 168/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (77,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctcgggattcaacttcaagtccaacaccatgaattgggtccgccaggctccagggaaggggctgcagtggctctcgtctattggtagcgtgggcgatttcatttattatgcagacgccgtgaagggccgattcaccgtttccagagacaacgccaagaacacactttatctggaactgaacagcctgacagtcgcggacgcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20795 JY8QFUQ01B3E28 unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKELGEGPDWELLP#YFHYW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaattgggggagggccctgactgggaactactaccagtactttcactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 20796 JY8QFUQ01A5V9M productive Homsap IGHV3-48*02 F 864 88.94 193/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + ctctggattcacctttagtgattatagaatgaattgggtccgccaggctccagggatggggctggaatgggttgcacacattagtaccagtggtagtagtatatactatgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcactttttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 20797 JY8QFUQ01CKFRG productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame + tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20798 JY8QFUQ01B0ZV3 unproductive (see comment) Homsap IGHV3-66*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD6-13*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDSPYSSGWSDGF*CL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 65 in the user submitted sequence), (cause frameshift) cctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctgagtgggtctcaattatttatatcagtggtagcacatactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaagaacacggtgtatcttcagatgaacagtctgagagctgaggacacggctgtgtattactgtgcgagagatagtccatatagcagcggctggtctgatggcttttgatgtctgggggccaagggacaatggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 20799 JY8QFUQ01B76KB productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 863 89.3 192/215 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [0.17.38.11] CACGHMRDGYDVW in-frame + ctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20800 JY8QFUQ01ABKJ7 productive Homsap IGHV3-11*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARDDSCSGGSCYEYW in-frame - acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaagggccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20801 JY8QFUQ01BUMPR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDTITMGGDVAPLFDYW in-frame + ctctggattcacctttagtaactatgacatgggctgggtccgccaggctccagggaagggactggagtgggtctcaagtattacgactggtggtgagagaacttactatgcagactccgtgaagggccgattcaccatcgccagagacaactcccagagcacgatgtttctgcaaatgaacagcctgagggccgacgacgcggccatctactactgtgcgaaagacaccataacaatgggcggtgacgtcgctccactgtttgactactggggtcagggaaccctggtcaccgtctcctcgtcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgtctgcctggtccagggcttcttccctc 20802 JY8QFUQ01DCQZ3 No results 20803 JY8QFUQ01BW4UM unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.37.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 137 in the user submitted sequence), (cause frameshift) cctctggattcaccttcagtagttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcttgcattagaagtagtggtgatgacgtattctacgcggactcagtgaagggccgattcacatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgtgcgagagatgttccgggtgacaacgttggacgtactgggccagggcggaaccccggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20804 JY8QFUQ01BN5AH productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20805 JY8QFUQ01A0EXZ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 891 89.86 195/217 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20806 JY8QFUQ01BX863 unproductive Homsap IGHV4-39*03 F 929 91.36 201/220 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSITLTVVVMNDAFDV## out-of-frame + tctccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctgggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20807 JY8QFUQ01CLWE2 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20808 JY8QFUQ01CXKO7 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggGggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20809 JY8QFUQ01DMZC9 productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20810 JY8QFUQ01CZ6QA productive Homsap IGHV3-11*01 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20811 JY8QFUQ01C7IHT No results 20812 JY8QFUQ01CCTAQ No results 20813 JY8QFUQ01CIR3P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20814 JY8QFUQ01ASHC2 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGEFYYETSGRRGFELL# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcactacctcctggatgcactgggtccgccaagctccagggaaggggctaatgtgggtctcacgtgtgaataaggatggcagtagtacaagttatgaggactccgtgaagggccgattcaccatctccagagacaacgccaagaccacgctgtacttggaaatgaacagtctgagagtcgaggacacggctatgtattattgtgcaagaggagaattttattatgaaactagtggtcgaaggggttttgaactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20815 JY8QFUQ01BC283 productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 277 80.46 70/87 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.29.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (80,46% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20816 JY8QFUQ01C21C9 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 760 83.8 181/216 nt 82.41 178/216 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD4-11*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARDSALFGYARYDAMDAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); tctggatccagGtttcagtggcttTtggcgtgaactgggtccgccaggctccagggaaggggctggGaatgggtctcacacgtcaatagtgccagtgactacaaatattacgcggactcagtgaggggccggttcaccatttccagaaacaatgccaagaactcagtgtatctgcgaatgaataacctgagagacgacgacacggctctatattactgtgcgagagacagcgccttattcggctacgctaggtacgacgctatggacgcctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcgggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgctcggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20817 JY8QFUQ01CWOUE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 830 88.21 187/212 nt 87.74 186/212 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 7 8 17 7.8.17 [X.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'T' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); gattcagcttaagttcttatggcatgaactgggtccgccaggctccaTgggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20818 JY8QFUQ01B22ZO unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD6-25*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG# out-of-frame + ctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagcggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggccagggagccctggtctccgtctcctcagcatccccgaccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20819 JY8QFUQ01BWYJK No results 20820 JY8QFUQ01C2TGT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 951 92.73 204/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 20821 JY8QFUQ01AL2IL productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20822 JY8QFUQ01B8TFF unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt 99.1 220/222 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20823 JY8QFUQ01ABZLF productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20824 JY8QFUQ01BU904 No results 20825 JY8QFUQ01CGPJ4 productive Homsap IGHV3-7*03 F 855 88.48 192/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame - ctctggattcaccttcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20826 JY8QFUQ01CVY0F productive (see comment) Homsap IGHV4-39*03 F 928 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 9 7 17 9.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift) ctccggtggctccatcaacagtagaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20827 JY8QFUQ01DDL1C unproductive (see comment) Homsap IGHV3-7*01 F 1044 98.16 213/217 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDPYSSGRGHF*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttagtttctattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatccgtatagcagtggccgggggcacttttgactactggggccaggggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20828 JY8QFUQ01AEWIJ No results 20829 JY8QFUQ01C2YXQ No results 20830 JY8QFUQ01AIGW8 unproductive Homsap IGHV3-13*01 F 971 94.88 204/215 nt 93.95 202/215 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 X 8.7.X [1.17.38.11] CAEGRQK#YNWFDPW out-of-frame - in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtaattacgacatgcactgGggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaAagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20831 JY8QFUQ01A9S2H productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 804 86.45 185/214 nt 85.98 184/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgactacttcatacactggctgcgacaggCcccctggacaacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20832 JY8QFUQ01B8Q7B unproductive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1115 100.0 224/224 nt 99.55 223/224 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD4-17*01 F 2 8 10 X 8.10.X [1.17.38.11] CTKCSVTIYFFGLL# out-of-frame + stop codons in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccAaaaagcatcgcctatctgcaaatgaacagcctgaaaaccgaggacacagccgtgtattactgtactaagtgttcggtgactatttacttttttggactactggggccagggtaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggctacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20833 JY8QFUQ01A35C3 productive Homsap IGHV4-34*06 F (see comment) 701 80.84 173/214 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 8 7 14 8.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame + Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tccatggtgggtccctcaggggttacccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20834 JY8QFUQ01BZF3U productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 216 to 216 in the user submitted sequence), (cause frameshift); tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatTtcctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 20835 JY8QFUQ01CBS6J productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggccccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20836 JY8QFUQ01A1CTT productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 945 93.09 202/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CG' (2 nucleotides at position 75 to 76 in the user submitted sequence), (cause frameshift); ttctggaGtacacgtttatgaattactggatcggctgggtgcgccagatgcccgggAaaaggcctggagtggatCGggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 20837 JY8QFUQ01B1YVE No results 20838 JY8QFUQ01AU5W7 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CAMRFLWWS*VLPLS*QL# out-of-frame + stop codons Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggttcacattcagtaactactggatccactgggtccgccaagctccaggaaaggggctagagtgggtcgcacgtattaatgatgctggaaagcgtgccgacttcgcgactttcgtgaagggccgattctccatctcccgagacaacgccaagaacacagtgtatctggaaatgactagtctgagagtcgacgacacggctgtctatttttgtgcaatgcgatttttgtggtggtcctgagtgctacccttatcttgacaactgggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20839 JY8QFUQ01A9228 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame + ctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactc 20840 JY8QFUQ01AZAAF unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRVYGGGRA##DHW out-of-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggaggggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20841 JY8QFUQ01C82LB No results 20842 JY8QFUQ01CF7WP productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1016 97.21 209/215 nt 95.35 205/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 147 to 147 in the user submitted sequence), (cause frameshift); ctggatacaccttcaccagctactatTttgcactgGggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccaggGgacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20843 JY8QFUQ01CLNZR productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 841 87.96 190/216 nt 87.5 189/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSGPSGYARYESMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); tctggattcagcctcacttcctatggcatgaactgggtccgccaggctccagggagggggctggagtgggtctcacacgttaatatgggtagtactcacatatactacgtaggctccgtgaggggccgattcaccatctccagagacgacgccaagaactcagtgtatctgcagatgaacaacctTgagagccgaggacacggctctatattactgtgtgagagatagtggcccgtccggctacgctaggtacgagtctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20844 JY8QFUQ01BZN3J productive (see comment) Homsap IGHV4-61*02 F 990 95.39 207/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*02 F 2 9 7 15 9.7.15 [1.17.38.11] CARAGKQDFWSGYSDDW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'GTG' (3 nucleotides at position 21 to 23 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 3 nucleotides (from position 23 in the user submitted sequence), (do not cause frameshift) ctctggtggctccatcggcaGTGgtagttattactggagctggatccggcagcccgccgggaagggactggaataccttgggcgtatctataccagtgggagcaccaactacaaccCcctccctcaagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgctgacacggccatttattactgtgcgagagcggggaaacaggatttttggagtggttattctgacgactggggccagggaaccctggtcatagtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20845 JY8QFUQ01COX06 No results 20846 JY8QFUQ01AE2VJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 775 84.02 184/219 nt Homsap IGHJ1*01 F 170 80.77 42/52 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CARPDGGNGWAAKYFQMW in-frame - Low V-REGION identity (84,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctgggttctcgtttaatagttatggtatgacatggttccgccaggctccggggagggggctggagtgggtctcatctataactggaactgggggtaacgttttctacgcagacttcgtgcagggccggttcaccatctccagagacaattccgacaatatgttgtttctgcaaatgaacagcctgagagttgaggacacggccgtgtattactgtgcgagacctgacggaggcaatggctgggccgcaaagtactttcagatgtggggccagggcacccttctcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20847 JY8QFUQ01CGTHL productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.16.38.11] CARAPRTATLLDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccaggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20848 JY8QFUQ01AVOUX productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaagggactacttcccccgaaccggtgacggtgtcgtggaactcagg 20849 JY8QFUQ01BC320 productive Homsap IGHV1-2*02 F, or Homsap IGHV1-2*03 F (see comment) 373 77.78 98/126 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 X 4 12 X.4.12 [X.X.38.11] CARGPVSGWYTDYW in-frame - Low V-REGION identity (77,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ggatacaccttcaccgtctactatctattctggggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20850 JY8QFUQ01BYZBL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDWSIGARFPQGAFDIW in-frame + cctctggattcacctttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctctttcattagtggtaatggtggtagcatagactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaatacgctgtatctgcaaatgaatagtctgagagccgaggacacggccgtctattactgtgcgaaagattggagtataggagcacgtttcccccaaggagcttttgatatctggggccaaggggaattggtcaccgtctcttcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20851 JY8QFUQ01C5RSZ productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20852 JY8QFUQ01B49G5 unproductive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDDDFWEW*T#FDPW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagtcttaataactactggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaatataaaaaaagatggaagtgagaaatactatgtggactctgtgaagggccgtttcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagaggcgaggacacggctgtgtatcactgtgcgagagacgacgatttttgggaatggtaaacacttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20853 JY8QFUQ01B4YMU productive Homsap IGHV3-48*01 F 891 90.32 196/217 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARESTWEFTPDSW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaatttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20854 JY8QFUQ01BPQPP No results 20855 JY8QFUQ01CX3WO No results 20856 JY8QFUQ01A5W0Y No results 20857 JY8QFUQ01CH28M productive (see comment) Homsap IGHV3-48*01 F 929 91.4 202/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [2.17.38.11] CAKVGSMNIEASPPDDW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ccgtctctggattcagcttcagttcctatagcatgagctgGggtccgccaggctccggGggaaggggctggagtgggtctcatatattagtagtagtggtaggaccatctactacgctgactccgtgaagggccgattcaccatgtccagagacaatgccaagaattcactgtatctacaaatgaacagcctgagagccgaggacacggccgtctattactgtgcgaaagttggcagcatgaatatcgaggcgagccctcctgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20858 JY8QFUQ01AGRAL productive Homsap IGHV3-33*05 F 945 92.63 201/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - gtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagggccgattcaccatctccagagacaattccaggaacacactgtatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20859 JY8QFUQ01C1WE0 No results 20860 JY8QFUQ01CLNGA No results 20861 JY8QFUQ01C1ROT unproductive Homsap IGHV3-11*01 F 976 94.91 205/216 nt 94.44 204/216 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRRVWGYSYGSVSYYFEY## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 69 of V-REGION: 'A' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgactactacatgaactggatccgccaggctccagggaaggggctggagtgggtttcatacattagtggcagtgctactaccatatcctacgcaAgactctgtgaagggccgattcaccatctccagggacaacgccaaaaactcactttatctgcaaatggacagcctgagagccgaggacacggccatatattactgtgtgaggcgggtgtggggatacagttatggttccgtttcgtactactttgaatactggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20862 JY8QFUQ01AKZ01 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20863 JY8QFUQ01CLW3Q productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 872 87.95 197/224 nt 87.5 196/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-13*01 F 1 8 10 14 8.10.14 [1.17.38.11] CAREGYISTWYLFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); ctatggggttcacgtttggtgattatcctttaagctggttccCgccaggctccaggcaagaggctggagtgggtaggtttcattagacccagtgcttatggtgggacaagagaatacgccccgtctatgaaaggccgattctccatctcgagagatgactccaaaagtgtcgcctatctgcaaatgaacagcctgagaacggaggacacagccgtatatttctgtgctagagagggttacatcagcacctggtacctctttgactcttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20864 JY8QFUQ01C3753 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 804 85.98 184/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found tggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20865 JY8QFUQ01AYAO5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRSGRDGG#WFDSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcatctttgccgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctacaaagacggttccaagaatacgatgtatctgcaaatgaggaccctgagagacgacgacacggccaaatattactgtgcgagacgaagtgggcgtgatgggggcctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20866 JY8QFUQ01DFYHU No results 20867 JY8QFUQ01B4IIY unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 959 93.58 204/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CVKDLLGGDPF#W out-of-frame - Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtcgctatggcttgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcagatgatgggaagaataaattctatacagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgatgtttgtgcaactgaacagtctgagagctgaggacacggctgtgtattactgtgtgaaagacctactaggtggtgacccctttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20868 JY8QFUQ01BJRF9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARDGEWEMLDHW in-frame + ctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaggggctggtgtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagctctgcagccacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20869 JY8QFUQ01CDXDA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgctagtactacttccatacactatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20870 JY8QFUQ01B9I8D productive (see comment) Homsap IGHV3-7*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'CCA' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaAaagggctggagtgggtggccCCAcataaaacccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggcccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactc 20871 JY8QFUQ01A1KQO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20872 JY8QFUQ01ABGGA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20873 JY8QFUQ01CRRQI productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 20874 JY8QFUQ01CXT9Y productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARGTRYNNGLDAFDVW in-frame + Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctcgagtgcctccatgatcagttactattggacctggattcggcagcccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgcttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20875 JY8QFUQ01AZSTY productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 879 89.09 196/220 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.17.38.11] CVRHVRRFWFDPW in-frame + ctctaatggctccatcagcggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20876 JY8QFUQ01B17JU productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggGggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20877 JY8QFUQ01AKZW4 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctatggtgggtccttcagtggttacacctggaactggatccgccagcCccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 20878 JY8QFUQ01CBUHR productive Homsap IGHV4-61*02 F (see comment) 650 77.38 171/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARERDRSIGGAAELDSW in-frame + Low V-REGION identity (77,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccaatgtacccatcagtcgtggaggttactactggaattggatccggcaggccgccgggaaggggctggagtggcttggacgtgttgacagtaatggattcgtcaggtacaattcttccctcaaaagtcgcctttctatgtcactagacacgtccaagaatcagatctccctgatattgaggtctgtgatcgccgcagacacggccgtatatttctgtgcgagggagcgtgataggtcgatcggtggagcggcagaacttgactcctggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20879 JY8QFUQ01CD5I4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaAactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20880 JY8QFUQ01A9KUR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 958 93.98 203/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - tctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20881 JY8QFUQ01AC8AS No results 20882 JY8QFUQ01CN2FS productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20883 JY8QFUQ01CHAXX No results 20884 JY8QFUQ01CVW6G No results 20885 JY8QFUQ01A8MS3 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F or Homsap IGHV4-61*01 F 971 94.88 204/215 nt 94.42 203/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD4-23*01 ORF 3 8 7 14 8.7.14 [1.17.38.11] CARLTTAVGGWSFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); tctctggtggctccatcgatagttactacCtggacctggatccggcagcccccagggaagggactggagtggattggctatatgtattacagtaggagctccaactacaacccctccctcaagagtcgagtcaccatttcagtagacacgtccaagaagcagttctccctaaacctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgactacggcggtgggtggctggtcttttgatatctggggccaagggacaatggtcagcgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20886 JY8QFUQ01AO38F productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20887 JY8QFUQ01BEBPT unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt 95.41 208/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDRVYGGGRA##DHW out-of-frame - stop codons in FR3-IMGT at codon 71 of V-REGION: 'T' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 156 to 156 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtTgaagggccgactcaccatctccagagacaattcCcaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggaggggggcgagccgcttgaccactggggccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20888 JY8QFUQ01C8K0R productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagacCtccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggctgacggtgtcgtggaactca 20889 JY8QFUQ01B9VNB productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 51 to 52 in the user submitted sequence), (cause frameshift); tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccCAgggaagggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20890 JY8QFUQ01C5D21 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20891 JY8QFUQ01BH0ZP unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P or Homsap IGHV3-71*01 P or Homsap IGHV3-71*02 P or Homsap IGHV3-72*01 F 83 86.36 19/22 nt 5 X X 5.X.X [1.X.X.X] null + No rearrangement found cctctggattcacgtttagaga 20892 JY8QFUQ01A52XO unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 768 84.58 181/214 nt 83.64 179/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.37.11] CARERGSGPP#GMDVW out-of-frame - Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 189 to 189 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 100 of V-REGION: 1 nucleotides (from position 203 in the user submitted sequence), (cause frameshift) gttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagcCcccgaggacacggcgtctactactgtgcgagagaaagaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20893 JY8QFUQ01B9XYH No results 20894 JY8QFUQ01CXAGM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CMNELGYCSGGG in-frame - ttctggattcacttttagcagtcatatgatgagttgggtccgccaggctccagggaagggactggaatgggtctcaagtattcgtgccagtggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacagcctgagagtcgaggacacggccttatattactgtatgaacgaactcggatattgtagtggtggggggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20895 JY8QFUQ01DA39V productive Homsap IGHV4-61*02 F 803 85.07 188/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 10 7 16 10.7.16 [1.17.38.11] CAREHSSSIGGERELDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tgtctggtggccccatcagcagtagtggcttcgcctggacctggatccggcagaccgccgggaagggactggagtggatcggacgtgtttatggtagtgggaataccaattacagtccttccctccagagtcgagtcaccatatcagtagagacgtccaagaatcagttctccctgaggttgacttctgtgaccgccgcagacacgggcctatattactgtgcgagagaacatagtagttcgattggcggagagagagaacttgactcctggggccagggaacccaggtcaccgtctcctcagcatcccctgaccagccccaaggtcttccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 20896 JY8QFUQ01CSEO4 No results 20897 JY8QFUQ01ASUN0 No results 20898 JY8QFUQ01B0AOD No results 20899 JY8QFUQ01A2ZSQ No results 20900 JY8QFUQ01BCUN9 unknown (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 818 86.98 187/215 nt 85.12 183/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'C' (1 nucleotides at position 112 to 112 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'T' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaggagttattattggagttggatccggcagcCccccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaaCcccctccctcaagagtcgagtcTcccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagagggggtactttcgactactggtgaccagggttcatcggctnttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtccgtggaactcag 20901 JY8QFUQ01B1X31 No results 20902 JY8QFUQ01AZ0N5 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame - tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20903 JY8QFUQ01B4F48 productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 989 95.81 206/215 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-17*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARAEDYGDLTFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtacttacttctggagctggatccggcagcccccaggaaagggactggagtggattggctatgtctatcacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagtaatgtgaccgctgcggacacggccgtgtattactgtgcgagagcagaggactacggcgacctcacctttgactcctggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20904 JY8QFUQ01CE6Z9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20905 JY8QFUQ01CB9GB No results 20906 JY8QFUQ01DI39D productive (see comment) Homsap IGHV1-24*01 F 993 96.26 206/214 nt 95.79 205/214 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [0.17.38.11] CAIGAMATW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaAaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatggggaacgtggtcatcgccctgcctggtccagggcttcttccccccag 20907 JY8QFUQ01A08BN unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVWG*LSL#DYW out-of-frame + stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggtagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggctcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20908 JY8QFUQ01A4KIW productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccctaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20909 JY8QFUQ01BJG01 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 962 94.42 203/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons ctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgctagtactacttccatacactatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20910 JY8QFUQ01C1AAH unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 281 65.54 97/148 nt 8 8 X 8.8.X [1.17.14.X] null - No rearrangement found Low V-REGION identity (65,54% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20911 JY8QFUQ01A6TPF unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt Homsap IGHJ5*02 F 156 78.43 40/51 nt Homsap IGHD5-24*01 ORF 3 8 7 X 8.7.X [1.17.38.11] CARAPRTATLLD#PG out-of-frame + tctctggcgactccatcagtggtcactactggagctggatcaggcagcccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccagttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgaccccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20912 JY8QFUQ01CI4AA productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARDPVGISGSVNWFDPW in-frame - ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgactagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20913 JY8QFUQ01B970X No results 20914 JY8QFUQ01DBLR3 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcCgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20915 JY8QFUQ01B7NSM unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-7*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDCDSGECNFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctggattcagcttcagtacctataacatgaactgggtccgccaggctccagGggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccgagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20916 JY8QFUQ01CGB1G productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20917 JY8QFUQ01A76FU productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 919 91.32 200/219 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [2.17.38.11] CTREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcacctttgatgattttggcatgagatgggtccgccaagtcccagggaaggggctacagtgggtctctgggattaattggaatggtgctaaaacaggttatgcagcctctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtacgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20918 JY8QFUQ01B5R5Y unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 739 82.19 180/219 nt 80.82 177/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGGTDFDY## out-of-frame - Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); gcctctggaAtttacatttagtgattataatatgaattgggtccgccgggctccagggaaggggctggaatatgtcgcaaccattacaactgggagtggtcaaatctactacagtgactcagtgaggggccgcttcaccatctctagagacgacgccaagaattcactttatctgcagatgaacaacctgagaggcgaggacacgGgctgtctaTtttttgtgcgagaggggggactgattttgactattgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20919 JY8QFUQ01B606B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 15 8.8.15 [1.17.38.11] CVRGGVSGAFRWGFDYW in-frame + ctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccaagaacacggtgtatctacaaatgaacagtctgagagccgacgacacggctgtttactactgtgtgagagggggagtcagtggggccttcaggtgggggtttgactactggggccagggaaccctggccaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20920 JY8QFUQ01DB6AG productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20921 JY8QFUQ01B0BK5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20922 JY8QFUQ01BKXRL unproductive Homsap IGHV3-7*01 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSSPYFYDSNGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20923 JY8QFUQ01ARK7T productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARGGQRTGWYEYW in-frame + cctctggattcacctttagtacctattggatgacttgggtccgccaggctccagggaaggggctggagtgggtggccagcataaaaaatgatggaagtgagaaatcctatgtggactctgtaaagggccgattcaccatctccagagacaacgccgagaactcactgtatttgcaagtgaacaacctgagagccgaggacacggctgtatattactgtgcgagagggggccaaagaactggctggtacgaatattggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 20924 JY8QFUQ01B4T36 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [1.16.38.11] CVRHVRRFWFDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggtgactccatttccagtactagttattactggggctgggtccgccagcccccagggaagggctggagtggattgggggtatctattctagtgggaccacctacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20925 JY8QFUQ01BEWM9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKYVEGVVIYGGLL##SYAMDVW out-of-frame - ttctggattcgcctttagccgttatgccatgacttgggtccgccagactccagggagggggctggagtgggtctcaggtctcagtggtagtggtgatagcacatactactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggagggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20926 JY8QFUQ01AMSIH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - tctggattcaccttcagtagttatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20927 JY8QFUQ01BF2Q2 unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGYGYRGIYFFDY## out-of-frame + cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaaccggtgacggtgtcgtggaactca 20928 JY8QFUQ01AUH1C productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 984 95.79 205/214 nt 94.86 203/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [0.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); tggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaGggggctggtgtgggtctcacgtgttaatggtgatgGggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20929 JY8QFUQ01DAY2V productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 776 83.71 185/221 nt 83.26 184/221 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (83,71% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); aatgtctgggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGgggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20930 JY8QFUQ01DLO83 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1004 95.87 209/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CARPGGNCLL*WW*#CYDPW out-of-frame + stop codons cctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggaattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 20931 JY8QFUQ01AD0K5 unproductive Homsap IGHV3-11*01 F 862 89.67 191/213 nt 88.73 189/213 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [1.16.38.11] CARDPYCSSTNCYPY## out-of-frame - in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 3 nucleotides (from position 93 in the user submitted sequence), (do not cause frameshift) ctctggattcaccctcagtgactactacatgagttggttccgccaggctccagggaagggctggagtggctttcatacattgcaggaagtggaaccacatattacgcagattctgtgaagggccgattcaccatctccagggacaatgccgagcactcggtatacctgcaaatgaacagcctgagagtcgaagacacggccgtgtattactgtgcgagagatccctattgtagtagtaccaactgctatccctactgggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20932 JY8QFUQ01BA1IP No results 20933 JY8QFUQ01CEBPR productive Homsap IGHV4-34*08 F (see comment) 719 81.86 176/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-14*01 ORF 3 8 7 13 8.7.13 [1.17.38.11] CARGRDYNQNDLGHW in-frame - Low V-REGION identity (81,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagcagctatgccatgagttggatccgccagcccccagggaaggggctagagtgggttggagaagtcaatcatagtggagagccctactacaatccgtccctcaagagtcgagtcagcatctcactagatacatccaagattcatttcaccctaaaactgacttctgtgaccgccgcggacacggctgtgtattactgtgcgagaggccgtgactataaccagaacgaccttggccactggggccagggagccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20934 JY8QFUQ01BSZAM productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 90.19 193/214 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD2-21*02 F 3 8 7 16 8.7.16 [1.17.38.11] CAREFRAPSLARYGMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctcggggttcagcgtcagtaataacttcatgacctgggtccgccaggttccagggaaggggctggagtgggtctcagttatttatagcaatggtgaaacaatctacgcagactccgtgaagggccgattcactatgtccagagacaattccaagaacacactgtttcttcaaatgaacagcctgagaggcgaggacacggccgtgtaccactgtgcgagagaatttcgggcgccttctttggccagatacggtatggatgtctggggccacgggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20935 JY8QFUQ01C8MN4 productive (see comment) Homsap IGHV2-5*02 F 1102 94.67 231/244 nt 93.85 229/244 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 10 7 14 10.7.14 [9.17.38.11] CAHIRAELSTSCHAFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift); gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagcccccaggaaAaggctctggagtggcttgcacttgtttattgggatgatgataancgctacagctcatctctgaagagcagactcaccatcaccaaggacacctccAaaaaaccaggtggtccttacaatgactaacatggaccctatggacacagccacatattactgtgcacacattagggcggaacttagtaccagctgccatgccttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 20936 JY8QFUQ01B2NXU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 620 93.01 133/143 nt 92.31 132/143 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 7 1 X 7.1.X [1.X.38.11] CVSDLAGQKGF## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (1 AA in JY8QFUQ01B2NXU ; 8 AA in Homsap_IGHV3-74*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT, from codon 38 of V-REGION: 75 nucleotides (from position 27 in the user submitted sequence), (do not cause frameshift) cctcaggattcaccttcagtagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20937 JY8QFUQ01DSG0R No results 20938 JY8QFUQ01CRE1B productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 922 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - tctggagttcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgaganccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20939 JY8QFUQ01A2P3S unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20940 JY8QFUQ01C094X productive (see comment) Homsap IGHV3-43*01 F 994 95.83 207/216 nt 95.37 206/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD2-8*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDRIGSLYYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift); tcaggattcacatttgGctgaatataccatgcactgggtccgtcaagttccggggaagggtccggagtgggtctctcttattagttgggatggtggcagcacatactatgcagactctgtgaagggccgattcaccatctccagagacaacagcaaggactccctgtatctgcaaatgaacagtctgagaactgaggacaccgccttgtattactgtgcaaaagataggattgggtccttgtactactttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20941 JY8QFUQ01BC3A6 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - tttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20942 JY8QFUQ01CJ3AN unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF## out-of-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 20943 JY8QFUQ01C94U1 productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 9 7 16 9.7.16 [1.17.38.11] CARERSASIGGAGEIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 37 of V-REGION: 3 nucleotides (from position 30 in the user submitted sequence), (do not cause frameshift) tctctggcggccccatcagtggtggtggttactggagttggatccggcagcccgccgggaagggactggagtggatcggacatatttataatagtgggaacatcaactacagtccctccctcaagagtcgggttttcatgtcagtagacacctctaagaagcagttttccctgaggttgaactctgtgaccgccgcggacacggccgtgtattattgtgcgagagaacgtagtgcttcgattggcggagcgggagagattgactcctggggccagggaatcctggtcaacatctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20944 JY8QFUQ01C4MK3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 838 87.21 191/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 8 8 10 8.8.10 [2.17.38.11] CATWIQSHFDYW in-frame + gcctctggattcacatttagtcactataccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagccattaatcaagatgccattaccacacactacccagactccgtgaagggccgcttcaccgtctccagagacaattccaagaacacactctatctgcaaatgagcagcctgagagccgacgacacggccgtatattattgtgcgacgtggatacagtctcactttgactattggggccagggaaccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20945 JY8QFUQ01BON0E productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDHIWAFDFW in-frame + ctctggattcaccttcagtgactatagcatgaactgggtccgccagactccagggaagggggtggagtggatttcatacatcggccgtggtggtgatgggatatactacgcagactctgtgaagggccgaatcaccatctccagagacaatgccaagaactcactttttctgcaaatgaacaccctgagagacgacgacacggctgtgtattactgtgcgagagaccacatttgggcttttgatttctggggccaagggacaaaggttaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20946 JY8QFUQ01CUERK productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 696 80.84 173/214 nt 80.37 172/214 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggCaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtnttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20947 JY8QFUQ01DBT4M unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGS## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggGggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtgggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 20948 JY8QFUQ01B6CKY productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 2 8 7 17 8.7.17 [1.17.38.11] CAKNLRLGHSYFYNALDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'C' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AAGG' (4 nucleotides at position 61 to 64 in the user submitted sequence), (cause frameshift); tctctggtggcctcatcagtaattactattggGacctggatCccggcagccccccaggaaAAGGgcacatggagtggattgggaacatctattacagtgggagcgccacctacaacccctccctcaagagtcgagtcaccatatcaatagactcgtccaagaaccagttctccctgaggctgaccgctgtgaccgctgcggacacggccgtgtattactgtgcgaaaaacttacgattgggtcacagttacttctacaacgctttggacgtatggggccaagggaccacggtcaccgtcgcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 20949 JY8QFUQ01CEXR5 productive Homsap IGHV4-61*02 F 893 89.59 198/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.17.38.11] CARQGDSSGPWNDYW in-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20950 JY8QFUQ01DJPEP unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 20951 JY8QFUQ01CLDAG productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagttactggatgcactgggtccgccaAaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20952 JY8QFUQ01B9SV9 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20953 JY8QFUQ01AVZIA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKKHYNSGTYLYNFDYW in-frame + ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaaacattataattcggggacttatttatacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 20954 JY8QFUQ01AM056 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 9 8.8.9 [1.17.38.11] CAKEEVPNDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'A' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); tctctggattcaccAtttagcaatgctgccatgacgtgggtccgccaggctccagggaaggggctagagtgggtctcaggtattagtattagtggtgatagaacatattacgcagactccgtgaagggccggttcaccatctctagagacaattccaagaataccgtgtatctgcaaatgaacagcctgagagccgaggacacggccatatattattgtgcgaaagaggaggtcccgaatgattattggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20955 JY8QFUQ01BBZCB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [2.16.38.11] CAKEEGATGVYYVDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 33 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) agcctctggattcacctttaccacctccgccaggcctgggtccgccaggttccaggaaggggctggagtgggtctcaactaGttagacctaGgtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20956 JY8QFUQ01BMQPC No results 20957 JY8QFUQ01CDMDY productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt 89.64 199/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggaTttgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagtccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20958 JY8QFUQ01AYXDN productive (see comment) Homsap IGHV4-61*02 F 884 89.14 197/221 nt 88.24 195/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 12 10.7.12 [1.17.38.11] C#RDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in CDR3-IMGT, from codon 105 of V-REGION: 1 nucleotides (from position 222 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccGggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20959 JY8QFUQ01DATD1 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CATISDYRFEFW in-frame - ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtctctgcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatacctggtccagggcttcttcccccag 20960 JY8QFUQ01B1YMM No results 20961 JY8QFUQ01ABPCL No results 20962 JY8QFUQ01CF74Q unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 792 84.79 184/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20963 JY8QFUQ01CAG3Y productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20964 JY8QFUQ01AK731 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20965 JY8QFUQ01CXN8M productive (see comment) Homsap IGHV1-8*01 F 840 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 101 of V-REGION: 'C' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccCgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 20966 JY8QFUQ01DLCGK unproductive Homsap IGHV3-7*01 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CARETLPLGVGG#FDNW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggGggctggagtgggtggccaacataagccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttggggggtttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20967 JY8QFUQ01C1R0Y No results 20968 JY8QFUQ01CXWFF productive (see comment) Homsap IGHV3-11*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagGggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 20969 JY8QFUQ01B29B8 No results 20970 JY8QFUQ01A5FUX productive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcacctTtcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20971 JY8QFUQ01AH32A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [1.17.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame + cctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20972 JY8QFUQ01ARP82 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 940 91.11 205/225 nt 89.78 202/225 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD1-14*01 ORF 1 8 10 17 8.10.17 [2.17.38.11] CTTAPSETYATEYFAMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'A' (1 nucleotides at position 188 to 188 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'AC' (2 nucleotides at position 202 to 203 in the user submitted sequence), (cause frameshift); gcctctggattcactttcagtaatgtttggatgagttgggtccgtcaggctccagggaaggggctggaatgggttggccgtattaAaaagcacaattgatggtgggacaacatcctacgctgcccccgtgaaagacagattcatcatctcacgagaggactcagaaaacaccttgtctctgcaaatgAaacagcctgaaaaACccgaggacacagccgtgtattactgtactacagccccaagcgaaacttatgcaacggagtacttcgctatggacgtctggggccaggggacaacggtcaccgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20973 JY8QFUQ01BEOD5 unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 110 68.0 34/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + stop codons cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggncatggtaatgtctcctagcatcccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 20974 JY8QFUQ01AI044 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 688 91.98 149/162 nt 91.36 148/162 nt Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-9*01 F 1 X 7 20 X.7.20 [X.9.38.11] CARHPRPGTFDYLWGGVGSTPG in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); gggaaggggctggagtgccttgggagcatcCttttatagtgggcgcaccaaccaggacccgtccctcaagagtcgagtcaccttatccgttgacacttccaagaaccagttctccctgaagctgagctctgtggccgccgcagacacggctgtgtattactgtgcgagacatccccgcccgggaacttttgactacttatgggggggggttggttcgacccctgggggccagggaattccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 20975 JY8QFUQ01B0CV7 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt 83.26 184/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARHRSFGVIIVNYFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tttccggtagttccatcagtagcagtgattactactgGgggctgggtccgccagTcccccagggaagggtctggagtggattggaagtgtctattacagggggacgcagtacctcaacccgtccctccagagtcgagtttccatttccattggcacgtccaagacgcaattctccctgagactgaggtctgtgaccgccgcagacacggctatgtattactgtgcgagacatcggtcttttggagtgataattgtgaattactttgagacctggggacagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20976 JY8QFUQ01BSPOJ unproductive (see comment) Homsap IGHV3-48*02 F 981 94.93 206/217 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons ctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20977 JY8QFUQ01CZEEB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-33*01 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F (see comment) 381 76.69 102/133 nt 75.19 100/133 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 6 16 X.6.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (76,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 76 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'A' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); gtctctggattcaccttcatcagttatgactcccgtgaagggccggttTcaccatctccagagacaAattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20978 JY8QFUQ01BVL5V unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 822 87.38 187/214 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPP#GMDVW out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20979 JY8QFUQ01CQ9Q9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame - cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 20980 JY8QFUQ01BHX3H productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 90.32 196/217 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.16.38.11] CARDLWLCSGGECYHRGGFENW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 113 to 113 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift) cctctgggttcaccttcagtGaactcctggatgcGactgggtccgcaaactccagggaagggggccgagtgggtctcacgtattaatagtgatgggagtaatacaatctacgAcggactccgtgaagggccgactcaccatctccagagacaacgccaaAaaacacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 20981 JY8QFUQ01CCX4A unknown (see comment) Homsap IGHV3-30-2*01 P, or Homsap IGHV3-30-33*01 P or Homsap IGHV3-30-52*01 P or Homsap IGHV3-33-2*01 P or Homsap IGHV3-54*01 P or Homsap IGHV3-54*02 P or Homsap IGHV3-54*04 P 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found actctggatt 20982 JY8QFUQ01CNTN4 productive Homsap IGHV3-9*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + ctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctgcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcaggc 20983 JY8QFUQ01BSBCH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ6*01 F (see comment) 144 69.84 44/63 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGLAVILGGFGRT# out-of-frame + Other possibilities: Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggacgtactggggccagggaacctggtcaccgtctcctcagcctccagccaaggccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtg 20984 JY8QFUQ01AWSWI productive (see comment) Homsap IGHV3-30*01 F 859 88.89 192/216 nt 87.04 188/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.37.11] CARDSVPRASEAAYHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 82 of V-REGION: 1 nucleotides (from position 149 in the user submitted sequence), (cause frameshift) ctctggattcGtccttcagaagttactctttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacattccaagaacacgctgtttctgcacatgaacagccTtgagagttgaggacacggctgtttaCtttttgtgcgagagattccgtacctcgggcgtcagaggctgcctaccactttgactattggggccagggaaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 20985 JY8QFUQ01BW66J No results 20986 JY8QFUQ01AK5T8 productive (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt 89.59 198/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AT' (2 nucleotides at position 98 to 99 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'AC' (2 nucleotides at position 124 to 125 in the user submitted sequence), (cause frameshift); tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcaGgcccccagggaagggactggagtggattggtcatttctatcacaATttgggggcactaagtacaacccctACccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20987 JY8QFUQ01B2XYK productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 863 89.3 192/215 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARRGSYGSGSYYPW in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctatggtgggtccttcagtacttactactggacatggatccgccagcacccagagaagggactggagtggattggggaaatcaatcacagtggaagccccaactacagcccgtccctcaagagtcgagtcctcatatcgatagacacgtccaagaatcaggtctccctcaacctcttctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20988 JY8QFUQ01A7H6S productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + tgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaagactacttccccgaaccggtgacggtgtcgtggaactcag 20989 JY8QFUQ01B65DZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CANEVGYCSGGG in-frame - tctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggagctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20990 JY8QFUQ01DWTOU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + ctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 20991 JY8QFUQ01A0207 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 20992 JY8QFUQ01C0T0E productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CGKPIVGATGREMPVSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20993 JY8QFUQ01DBMCS unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 980 93.3 209/224 nt 92.86 208/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARGGPHFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift); cctctgcagcctctgggAttcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggcccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 20994 JY8QFUQ01B7NNR No results 20995 JY8QFUQ01B2GU8 productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 91.63 197/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 92 to 97 in the user submitted sequence), (do not cause frameshift); tctctggtgtctccatcagtagtttctGactggagttggatgaggcagcCccccagggaggggactggagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 20996 JY8QFUQ01B1UMW productive (see comment) Homsap IGHV3-11*01 F 982 94.52 207/219 nt 94.06 206/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactcCtgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 20997 JY8QFUQ01C0LCZ unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1080 100.0 217/217 nt 98.62 214/217 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [1.17.38.11] CARGHCISTSCYWEIHYYYGMDV## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'A' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctatagcatgaactgggtccgccaggctccagggaaGggggctggagtgggtctcatccaAttagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20998 JY8QFUQ01CCD9I productive Homsap IGHV3-7*01 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [0.17.38.11] CARGSYWHYDTFGDYW in-frame - tggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 20999 JY8QFUQ01BLO0V unproductive (see comment) Homsap IGHV3-7*01 F 969 93.64 206/220 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-18*01 F 3 8 8 16 8.8.16 [2.17.38.11] CARVGYGYRGIYFF*LLG in-frame + stop codons agcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttcttttgactactgggggccagggaacccctggtcaccgtctcctcagctccaccaagggcccatcggtcttccccctggcgccctgctccagagcacctccgagagcacagcgccctgggctgctggtnaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21000 JY8QFUQ01BTHIY No results 21001 JY8QFUQ01B4FME productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame + cctctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcaccctccgagagcacagccgccctgggctgcctggtcaaggactaccttccccggaaccggtgacggtgtcgtggaactcca 21002 JY8QFUQ01AQCY5 No results 21003 JY8QFUQ01BNK8R productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 799 86.38 184/213 nt 84.51 180/213 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 7 9 8.7.9 [1.16.37.11] CTGLTYPDDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 57 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 57 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 120 in the user submitted sequence), (cause frameshift) gtctggatttaccttcagtaagttctggatgcattggtccgccaagctccagggaagggctgacttgggtctcacgtataatcctgatgggactatcacgaactacacggactccgtgagggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21004 JY8QFUQ01CH7L4 unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1049 96.04 218/227 nt 95.15 216/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGG*I**ELL*A#DFW out-of-frame + stop codons in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'AT' (2 nucleotides at position 137 to 138 in the user submitted sequence), (cause frameshift); ctccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccCccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaaATgtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggtagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggcttcttcccccg 21005 JY8QFUQ01DJ07A No results 21006 JY8QFUQ01BP78X No results 21007 JY8QFUQ01CY4KM unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKNRGVGDG*LVLRFL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 58 of V-REGION: 'ATG' (3 nucleotides at position 87 to 89 in the user submitted sequence), (do not cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattactaATGgtggtggtggtgtcgtactctacgcagactccgtgaagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttatttctgtgcgaaaaataggggggtcggcgatggctgactggtacttcgatttctgggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21008 JY8QFUQ01DLQMH productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame - acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21009 JY8QFUQ01DCK0R productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21010 JY8QFUQ01B7Z25 productive (see comment) Homsap IGHV3-9*01 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKNNGYFYDVAGYFDDW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 169 to 169 in the user submitted sequence), (cause frameshift); gcctctggattcacctttgacaattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtcgcaagtattagttggaatagtggaagcgcagactatgcggactctgtgcggggccgattcaccatctccagggacaacgccaagaactcccttTtttctgcagatgaacgatctgagacatgaggacacggccgtctatttctgtgtaaaaaataacggatatttctatgatgttgctggctactttgacgactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21011 JY8QFUQ01AAQDQ No results 21012 JY8QFUQ01B664T productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame + tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggtcacagcggccctgggctgcctggtcaaggcactacttccccgaaccggtgacggtgtcgtcggaactc 21013 JY8QFUQ01DL1HS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21014 JY8QFUQ01CB8LO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 3 8 8 14 8.8.14 [1.17.38.11] CAKVGVMSARDRIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); cctctggattcaccGtttagcaactatgccatgagttgggtccgccaggctcaagggaaggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaagtgggggtgatgtccgctcgagaccgcattgactactggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21015 JY8QFUQ01CPPNL unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1065 100.0 214/214 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD3-16*01 F 1 8 7 X 8.7.X [1.17.38.11] CASANYDYVWGELSL*LL# out-of-frame - stop codons ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttggggggagttatcgttatgactactgggggccagggaaccctggtcaccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21016 JY8QFUQ01BAK8M unproductive Homsap IGHV4-59*03 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD2-21*02 F 2 8 7 X 8.7.X [1.17.38.11] CARGRTVVTVIDYMDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); tctctggtgactccattagcggttactattggacctggatccggcaaacccccaggaaAAgggactggagtggattggaaatatccactacagtgggagcaccaagtacagtccctccctcaagagtcgagtcaccatatcactcgccacgtccaagaatcaattcgccctgaagttgacctctgtgaccgctgcggacacggccgtctattattgtgcgagaggacgaacggtggtgactgttattgactacatggactactgggggtcagggaacccctggtcaccgtctcctcagatccccgaccagccccaaaggtcttcccgctgagcctcctgcagacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21017 JY8QFUQ01B7RQH productive Homsap IGHV3-21*04 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21018 JY8QFUQ01DLJRJ productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame - tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21019 JY8QFUQ01A3LQU productive (see comment) Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt 81.11 176/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattccCccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21020 JY8QFUQ01DOV6Q No results 21021 JY8QFUQ01CN6IE productive (see comment) Homsap IGHV3-66*02 F 903 91.59 196/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) cctctggattcaccgtcagtagcagcttcatgaCtttgggtccgccaggctccaggaaaggactggagtgggtctcagtGcttttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21022 JY8QFUQ01CYHKC No results 21023 JY8QFUQ01BILLB productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1051 97.3 216/222 nt 96.4 214/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [2.17.38.11] CARLDYTRYFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagTttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaag 21024 JY8QFUQ01B88T2 No results 21025 JY8QFUQ01BAL7P productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1085 100.0 218/218 nt 99.08 216/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-2*01 F 2 8 8 17 8.8.17 [2.17.37.11] CAKPSSTSSRARTSHFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 178 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaatAaaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaagcctagtagtaccagctcccgcgctcgcacctctcactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21026 JY8QFUQ01BOFYV unproductive Homsap IGHV3-11*01 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CAKGETVVTPGDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaTggggctggagtgggtttcatacattagtaatggtggtagtctcgtattctacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatttacaaatgaatagtctgagacctgaggacacggccttatattactgtgcaaaaggagagacagtggtaactccaggagactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21027 JY8QFUQ01BUZGQ productive Homsap IGHV3-11*01 F 855 88.48 192/217 nt Homsap IGHJ4*02 F (see comment) 159 81.25 39/48 nt Homsap IGHD1-1*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGTTASW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctttggattcaccttcaaggactactacatgagttggatccgtcaggctccagggaaggggctggagtgggtctcatacatatctcatgatggtgcgaccaaatactacgcagactctgtgcagggccgattcaccgtctccagggacaacgccaagaactcactgtatctgcaaatgaacaacgtgagagccgacgacacggccttctattattgtgcgagagacctcgtgggcacaactgcatcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21028 JY8QFUQ01CIJGA unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 841 87.96 190/216 nt 87.04 188/216 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [2.17.37.11] CAKNNNDFGDYDWF#PW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctctgggtgtctccatcagtagttcctactggagttggatccggcagcccccagggaagggcctggagtggattggttatgtctattacTactgggggcaccgactccaacccctccctcaagagtcgtgtcaccctgtcaatggacacgtccagaaccagttctccttggaactgagctctgtgaccgctgcggacacggccgtctattactgtgcgaaaaacaacaatgacttcggtgactacgactggttcgaccctggggccagggaatgctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21029 JY8QFUQ01CJ620 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 835 88.26 188/213 nt 87.79 187/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.37.11] CARKGLVPSMFFFDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 192 in the user submitted sequence), (cause frameshift) ctctggtgggtccttcagtggttacttctggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccgggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21030 JY8QFUQ01DKPE3 No results 21031 JY8QFUQ01CF24Z unproductive (see comment) Homsap IGHV1-18*01 F 894 91.12 195/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [0.17.38.11] CARSHGGTAAGR#FDFW out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tggttacgcctttaagaactatggtatcaactgggtgcgacaggcccctggacaagggcttgagtggatggcatggatcagcgtatacaatggaaacacaaagtttgcaccgaggttccaggccagagtcaccatgactacagacacttccacgagcacagcctacatggaactgaggagcctgagatctgacgacacggccatgtattactgtgcgagatctcacgggggaacagcagctggacgaatttgacttctggggccaggggaccgtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21032 JY8QFUQ01A4RRU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKASPKWEFLRTTFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); cctctggattcaGcctttcgcagctatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtgctggtagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgacgacacggccatctacttctgtgcgaaggcgtcgccgaagtgggagtttctacgaaccacctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21033 JY8QFUQ01AE0GU No results 21034 JY8QFUQ01A0IZI productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 938 91.4 202/221 nt 90.5 200/221 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 82 to 84 in the user submitted sequence), (do not cause frameshift); cagcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaAaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21035 JY8QFUQ01AZY50 productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD2-2*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDSPSAYDPW in-frame + ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccctcagcctacgatccctggggccagggaaccctggtcaccgctctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21036 JY8QFUQ01CJGR0 No results 21037 JY8QFUQ01AL56R productive (see comment) Homsap IGHV1-2*02 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ2*01 F 256 98.11 52/53 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [0.17.38.11] CARDPGDPRSYWYFDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgactactatatacactgGggtgcgacaggcccctgggcaagggcttgaatggatgggatggaCccaaccctaagagaggtgactcgaggtatgcacagaagtttctgggaagggtcaccatgaccagggacacgtccctcactacaacttacatggaactgagcagcctcagatctgacgacacggccgtgtattactgtgcgagagatcccggagacccccgaagctactggtacttcgatgtctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21038 JY8QFUQ01DLUXO No results 21039 JY8QFUQ01B0AIT productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFGRT (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggacgtactggggccaggaacctggtcaccgtctcctcagctccagccaaggccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21040 JY8QFUQ01CEXGP productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 838 87.21 191/219 nt 86.76 190/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [2.17.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggGggctggagtgggtctcacgcattaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcccctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21041 JY8QFUQ01AS325 productive (see comment) Homsap IGHV3-48*01 F 1076 99.54 217/218 nt 99.08 216/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggGAagggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21042 JY8QFUQ01C88ZB unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 982 94.52 207/219 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CAGHLLGDPFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ggttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggcccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21043 JY8QFUQ01AORAJ productive Homsap IGHV1-8*01 F 817 87.32 186/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [X.17.38.11] CARGRGYGSYADHW in-frame - ggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21044 JY8QFUQ01DLT55 productive (see comment) Homsap IGHV3-23*05 F 836 87.91 189/215 nt 87.44 188/215 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-14*01 ORF 1 8 7 10 8.7.10 [1.17.38.11] CAKRPPGTIDRW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 96 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttggcacctctgacatggcctgggtccgccaggttccaggggaggggctggagtgggtctcacacattgatatcagaggtgccacacagtataaagactccgtgaagggccggttcaccatctccagagacaattccaagagcactctatatctgcaaatgaacaccttgcgagccgaggacacggccgtatattactgtgcgaaacgcccgcccggcaccatagatcgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctcgacagcacccccccgaagatgggaaaccgtggtcgtcgcatgcctggtccagggcttcttcccccaa 21045 JY8QFUQ01CM4YG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 1 8 8 18 8.8.18 [1.17.38.11] CAKVLAGATRDAYHYGMDVW in-frame + cctctggatttactttcagtaggtctgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggcattagtggtggtggtcttagcacatactacacagactccgtgaagggccggttcaccatctccagagacatttccaagaacacgctgtttctgcaaatgaacagcctgagagccgaggacacggccacatattactgtgcgaaagtcctggcgggagctacgagggacgcctaccactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagcatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21046 JY8QFUQ01CNZ0T unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21047 JY8QFUQ01DNKTR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 853 89.2 190/213 nt 86.38 184/213 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD1-26*01 F 3 7 8 21 7.8.21 [2.15.37.11] CAKYVEGWSYTGGYYNSYAMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 25 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 35 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 48 of V-REGION: 2 nucleotides (from position 58 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 2 nucleotides (from position 77 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 67 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) aacttctggattcgcctttagccgtatgccatgacttggtccgccagactccagggaggggctgagtgggtctcagtCtcagtggtagtggtgatagcacatacactcaaactccgtgaagggccggttcatcatcttcagagacaattccaagaacacgctgtatctgcaaataaacgccctgagagacgaagacacggccgtttactactgtgcgaaatatgtggaggggtggtcatatacggggggctactacaactcctacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21048 JY8QFUQ01C1HAH productive Homsap IGHV3-21*04 F (see comment) 658 78.08 171/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVRLFTSDGVRGDYW in-frame + Low V-REGION identity (78,08% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggtttcatcttcagtcacttcagcatgaactgggtccgccagactccaggaaagggcctggagtggatcgccgacatcagtagttcaagtgcatacatcacctatgcagattcagtcaggggccgattcgtcgtctccagggacgacgccaaggactccctgtacttgcaaatggacaacctgggagtcgacgatacggccacctattattgtgtgaggctcttcaccagcgatggagtgagaggcgactactggggccagggcgcccgggttctcgtctccgcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21049 JY8QFUQ01B0QWC productive Homsap IGHV3-48*02 F 986 94.95 207/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21050 JY8QFUQ01DQMT6 No results 21051 JY8QFUQ01CZEY6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDGVRGVGAYYIYYF#DLW out-of-frame + cctctggattcacctttggcctctatgccatgaactgggtccgccagactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactatttttcgacttatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21052 JY8QFUQ01DT4J9 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDASRYYYNSYCDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 213 to 213 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactGacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttatTttttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21053 JY8QFUQ01AT5B3 No results 21054 JY8QFUQ01C8610 No results 21055 JY8QFUQ01CTQAV unknown (see comment) Homsap IGHV2-5*03 F (see comment) 258 59.38 114/192 nt 10 7 X 10.7.X [9.17.27.X] null + No rearrangement found Low V-REGION identity (59,38% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gaccctcacgctgacctgcaccttctctgggttctcactcaacactgttggaatgggtgtgggctgggtccgtcagccccccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccta 21056 JY8QFUQ01CLVFK unproductive Homsap IGHV3-48*03 F, or Homsap IGHV3-48*04 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKDGSAIPVTGTYFEY## out-of-frame + gcctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccaagggagccctggtcaccgtctcctcagcttccaccaagggccccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgcccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21057 JY8QFUQ01DTBKZ unproductive Homsap IGHV3-30*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD3-3*01 F 1 8 8 X 8.8.X [1.17.38.11] CACGHMRDGYDVW# out-of-frame + in FR3-IMGT at codon 66 of V-REGION: 'G' (1 nucleotides at position 105 to 105 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaaGtactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctgggggcccaagggacaaaggtcaccgtctcttcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctcggtccagggcttcttcccccgagg 21058 JY8QFUQ01AVNX2 productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARAIGRPFYGMDVW in-frame - ctctggattctcctttgatatatattggatgagatgggtccgcctggctccagggaaggggctggagtgtgtggccgacataaagcaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtttctgcaaatgaacagcctgagagtcgaggacacgggtgtgtatttctgtgcgagagcgatcggacggcccttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21059 JY8QFUQ01BQSNT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CIMDLVGRADYW in-frame - cctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21060 JY8QFUQ01C8YUV No results 21061 JY8QFUQ01DOEOY unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [1.17.38.11] CTREVGSYRLL## out-of-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtggggagctaccgactactgggggccaggggaacccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 21062 JY8QFUQ01BMF7P productive Homsap IGHV3-66*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - ctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21063 JY8QFUQ01BZ1OJ productive Homsap IGHV4-39*02 F (see comment) 767 83.26 184/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [1.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame + Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21064 JY8QFUQ01CEQO2 unproductive Homsap IGHV3-7*01 F 1008 96.31 209/217 nt 95.85 208/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSGYYSTGY## out-of-frame - in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); ctctggattcagctttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 21065 JY8QFUQ01CWKZQ No results 21066 JY8QFUQ01BG0IA unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F 165 75.0 45/60 nt 8 X X 8.X.X [1.10.X.X] null - No rearrangement found gctctggattcaacttcagaacctattggatgggctgggtccgccaggcttcttccccca 21067 JY8QFUQ01CR4HU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21068 JY8QFUQ01CPCWU unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtc 21069 JY8QFUQ01BZEC4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 86.11 186/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [1.17.37.11] CARDDGGHMTLDV# out-of-frame + in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 155 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctgggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtggaactca 21070 JY8QFUQ01CDREL productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 7 12 8.7.12 [1.17.37.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 154 in the user submitted sequence), (cause frameshift) gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 21071 JY8QFUQ01AVF6B productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21072 JY8QFUQ01BFXCP unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 815 86.24 188/218 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKVGNLYFFEY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccgggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21073 JY8QFUQ01AM5NG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21074 JY8QFUQ01DRIRL productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt 93.21 206/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [1.17.38.11] CVRHRRLELLPDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 174 to 174 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccCctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccancccctcaaggtcttcccgctgagcctctgccagcacccagccagtgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21075 JY8QFUQ01A019O productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaCccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21076 JY8QFUQ01BMY2A productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 937 92.24 202/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [2.17.38.11] CARLPNTIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'CG' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift); gcttctggatatagtTtttggccaccactggatcggctgggtgcgccagaggcccgggaagggcctggagtggatCGgggggtcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatttcagccgacaagtccctcagtatcgcctacctgcagtggagcagcctgcaggcctcggacaccgccatatattactgtgcgagactgcctaacactattgactcctggggccaggggaccctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21077 JY8QFUQ01BYX2O unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 921 92.52 198/214 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [0.17.38.11] CAARI**WSLL##AFDIW out-of-frame + stop codons tggatacagtttcaccaactactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctggtgactctgatacccggtacaacccgtccttccaaggccaggtcaccttctccgtcgacaagtccatcaacaccgcctacttgcagtgggacagcctgaagacctcggacaccgccaagtattactgtgcggcgagaatttgatagtggtcattactggaatgctttcgatatatggggccaagggacgatggtcaccgtcgcttcagcatccccgaccagccccaaaggttcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 21078 JY8QFUQ01BBBC7 unproductive Homsap IGHV4-39*02 F 938 91.86 203/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 10 7 X 10.7.X [1.17.38.11] CARLLRVYDWYSQRGLL#DTW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); tctccgatggctccatcagcactagtaattactactgGgggctgggtccgccagcccccagGggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacgGgctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaagggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 21079 JY8QFUQ01A83DU No results 21080 JY8QFUQ01AV41Z productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 892 89.95 197/219 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKEQRGSGWSRSALDVW in-frame - gcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21081 JY8QFUQ01BEU3B No results 21082 JY8QFUQ01CR8CN productive Homsap IGHV3-30*19 F (see comment) 675 80.77 168/208 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 6 8 23 6.8.23 [X.17.38.11] CAKSEVVAVNEGLTLHYSYYRLDTW in-frame + Low V-REGION identity (80,77% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctgccggggattctgtcattcactgggtccgccaggctccaggcaggggactggaatggctggcagttatatcacaggatgcatattacacacattacacagacgctgtgaagggccgattcaccatctccagagacaactccaagaatatgctgtttctgcaaatgaacagtctgaggcttgaagacacggccgtctattactgtgcgaaatccgaggtcgtggctgtaaacgagggcctcaccctccactactcctactaccgtctggacacctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctgtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21083 JY8QFUQ01CW7W3 unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 91 79.31 23/29 nt 7 X X 7.X.X [2.X.X.X] null + No rearrangement found tctccgggggacagtgtctctaccaacag 21084 JY8QFUQ01BZ9NZ productive Homsap IGHV3-7*01 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame + ctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 21085 JY8QFUQ01CXV9K productive Homsap IGHV3-9*01 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - ctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21086 JY8QFUQ01CV8MT productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 766 83.56 183/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 2 8 8 9 8.8.9 [2.17.38.11] CTGLTYPDDYW in-frame - Low V-REGION identity (83,56% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattttaccttcagtaagttctggatgcattgggtccgccaagctccagggaaggggctgacttgggtctcacgtattaatcctgatgggactatcacgaactacacggactccgtgaggggccgattcatcacttccagagacaacgccaagaacacagtatatctgcagatgaacagtctgcgagtcgaggacacaggtgtatattactgtacaggactgacttatccagacgactactggggccagggatgtttggccaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21087 JY8QFUQ01DNAOD No results 21088 JY8QFUQ01BRSI9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 911 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [2.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); aggcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatacCtggtggtacaacagagtacgccgactccgtgaaGggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21089 JY8QFUQ01BOHMH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 956 92.76 205/221 nt 91.4 202/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [2.17.38.11] CARSGSGSHLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift); cagcctctggattcatcttcagtagctactggatgcactgggtccgccaagctccaGgggaaggggctggtgtgGggtctcacgtactaataCcgggggggactagcacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacggtgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21090 JY8QFUQ01CL2GL productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 956 92.76 205/221 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDALDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ttgcctctggattcatctttgatgattttggcatgagatgggtccgccaagttccagggaaggggctacagtgggtctctggtattaattggaatggtggtaaaacaggttatgcagactctgtgaggggccgattcatcatctccagagacaacgccaagaacgccctgtatctgcaaatgaacagtctcagagccgaggacacggccttatattactgtgcgagagaggtctcggacgccttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21091 JY8QFUQ01DBTOV unproductive Homsap IGHV1-2*02 F 921 92.52 198/214 nt Homsap IGHJ4*02 F (see comment) 114 70.83 34/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.17.38.11] CARGGRRGNYYWGI#DSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggatacacgttcaccgactactatgtccactgggtgcgacaggcccctggacaagggcttgagtggatggcgtggatcaaccctaacattggtgtcaccaagtctgcacaaaaatttcagggcagggtcaccatgaccagggacacgtccatcagcacagccttcatggagctgagcagcctgagatctgacgacacggccgtttattactgtgcgagaggggggcgacgtgggaactattattggggaatcttgactcctggggccagggaaccctggtcaccggtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21092 JY8QFUQ01BNKGX productive (see comment) Homsap IGHV3-7*01 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYYYYDTNGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); ctctggatttacctttacaaattattggatgagctgggtccgccaggctccagggaGgggggctggagtgggtggccagcgtaaaacaagatggaggtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggtcctactattattatgatactaatggcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21093 JY8QFUQ01DFN8I No results 21094 JY8QFUQ01CZE4H productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 855 88.48 192/217 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21095 JY8QFUQ01B6YPA productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 693 80.18 174/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARGLGLNAVYAFDVW in-frame + Low V-REGION identity (80,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctggggacaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21096 JY8QFUQ01CUQL5 productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); ctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgGggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21097 JY8QFUQ01CU5CB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'T' (1 nucleotides at position 172 to 172 in the user submitted sequence), (cause frameshift); cctctggattcacctTttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatTctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgncagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21098 JY8QFUQ01AZ407 unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*02 F or Homsap IGHV5-51*03 F 340 88.51 77/87 nt X X X X.X.X [X.X.29.X] null - No rearrangement found gtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactcgggggcgagggaaccctgagtttccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21099 JY8QFUQ01CPNTD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame + cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21100 JY8QFUQ01AA512 productive (see comment) Homsap IGHV3-66*02 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ6*02 F (see comment) 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 7 21 8.7.21 [2.16.38.11] CSSAAGLDCSGYSCYYFYHMDVW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gcctctgggattgaacgtcagtgcgaagttcatgagttgggtccgccaggctccagggaagggctggaatgggtctccactgtctctaacggtggtagtatatattatgcggactccgtgaagggccgatttagcgtctccagagacagctccaagaacacactgtttcttcaaatgaacggcctgagcggtggtgacacggctgtgtacttctgttcgagcgccgctggacttgattgttctggttacagctgttattacttctaccatatggacgtctggggccgagggacaacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggc 21101 JY8QFUQ01C91JV No results 21102 JY8QFUQ01CEVCS unknown (see comment) Homsap IGHV3-7*02 F 123 60.71 51/84 nt 8 1 X 8.1.X [2.17.X.X] null + No rearrangement found gcctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21103 JY8QFUQ01BPSNH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKFGGGSYYLELL*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcacctttaccacctatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtggtagtggtggcaggacatactacgcagactccgtgaagggccggttctccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcaaaatttgggggtggcagctactacttggaacttctttgactactggggcccagggaaccctggtcaccgtctcctcagcctccacaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaagaactacttccccgaaccggtgacggtgtcgtggaact 21104 JY8QFUQ01BWBPY productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgtggactccgtgaagggccgattcaccatctccCagagacaattccaagaacacggtgtatttgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21105 JY8QFUQ01ABKDV productive Homsap IGHV4-61*02 F (see comment) 614 75.57 167/221 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARERTNSIGGPRHLDPW in-frame + Low V-REGION identity (75,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtgctccgatcaacaatagtgattgctcttggacgtggatccggcagtccgccgggaggggactggagtggattggacgtgtccgtgtgaatggccagagcgactacaatccgtccttcggcagtcgtctcaccatgtccattgacacgtccaggaatcgattttccctgcaattgatctctgtgaccgccgcagacacggccctatattattgtgcgagggaacgtactaattccattggcggaccaagacaccttgacccctggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21106 JY8QFUQ01AU136 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.37.11] CAKDGARGGGSCFNSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 101 of V-REGION: 1 nucleotides (from position 206 in the user submitted sequence), (cause frameshift) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggcctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21107 JY8QFUQ01BXCKZ productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 849 88.79 190/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 7 8 15 7.8.15 [2.16.38.11] CAKSVSSGWPIDEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 37 of V-REGION: 2 nucleotides (from position 26 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 3 nucleotides (from position 48 in the user submitted sequence), (do not cause frameshift) ggctctggattcacctttaatagcttgcatgagttgggtccgccagtcagggagggggctggagtgggtctcagccattagtggcagtggtagtcggacatattacgcagactccgtgaagggccggttcaccatctccagagacaagtccaagaaaacgttgtatctacaaatgaacagcctgagagccgaggacacggccactttctattgtgcgaagagtgtgagtagtggctggccgatcgacgaaattgactactggggccaggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21108 JY8QFUQ01A3JL4 productive Homsap IGHV3-7*03 F 847 87.67 192/219 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [2.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gcctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaataaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21109 JY8QFUQ01DOYXH unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 679 94.08 143/152 nt 8 8 X 8.8.X [1.17.16.X] null + No rearrangement found cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaat 21110 JY8QFUQ01AWOO7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [1.17.38.11] CASFRVLESGYW in-frame + tctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21111 JY8QFUQ01BX3V8 No results 21112 JY8QFUQ01CAZTK productive (see comment) Homsap IGHV4-59*03 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD4-23*01 ORF 3 8 7 9 8.7.9 [1.17.38.11] CARGVTPEGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgggtgactccatcactcctaactcctggagctggatccggcagcCccccagggaagggactggagtggattggttatatctattacagtggaatcaccaagcacaacccctccctcaagagtcgagtcgccatttcagtagacacgtccaagaaccaattttccctgaggctgagttctgtgaccgctgcggacacggccgtttatttctgtgcgaggggggtcactccggagggctactggggccagggaatcttagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21113 JY8QFUQ01CBOD2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 425 80.92 106/131 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD5-24*01 ORF 3 X 5 16 X.5.16 [X.X.38.11] CVRYDYSRLHRSNYFGPW in-frame - Low V-REGION identity (80,92% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcatcagcttatgactccgtgaagggccggttcaccatctccagagacaattccaacaacacgctgtttctgcaaatgagcagcctgagagccgaggacacggccgtttattattgtgtgagatatgactactcacgcctacacagatccaactacttcggcccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21114 JY8QFUQ01B6UYE productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21115 JY8QFUQ01COFJ4 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 926 90.62 203/224 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 24 8.10.24 [1.17.38.11] CATDRPYYKKSLLADSGITTVWTFWG in-frame + tctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21116 JY8QFUQ01CER0W No results 21117 JY8QFUQ01BBQCT No results 21118 JY8QFUQ01AT1UN unproductive Homsap IGHV3-48*01 F (see comment) 734 83.73 175/209 nt 83.25 174/209 nt Homsap IGHJ1*01 F 125 71.15 37/52 nt Homsap IGHD5-12*01 F 1 7 7 X 7.7.X [X.17.38.11] CSRDGRRGYDLDS## out-of-frame - Low V-REGION identity (83,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 78 in the user submitted sequence), (do not cause frameshift) gattcaccttcggaacctatgccatgacgtgggtccgcctgactcctgggaaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctgggggccagggagccctggtcaccgtctcctcatcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21119 JY8QFUQ01B0HK9 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaGggggctggagtgggtgtcagatattagtgGggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgtaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21120 JY8QFUQ01CLL7S unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKT*LW#YYFDQW out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggGggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaaacatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21121 JY8QFUQ01AMAL4 productive Homsap IGHV4-61*02 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-9*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARCPNYNIGTRGFDYW in-frame + tttctggtgtctccatgagcaatgagtcctattactggacgtggatccggcagcccgtcgggaagggaccggagtggattgggcgcatctacaccagtgggagcaccaattataatccttccctcaagagtcgagtcaccatgtccttagacacgtccaagaggcagttctccctgaagttgacctctatgaccgccgcagacacggccacatatttctgtgcgaggtgtcccaattacaacattgggacccgggggtttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21122 JY8QFUQ01BWXXW productive Homsap IGHV3-48*02 F 896 90.37 197/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21123 JY8QFUQ01CNRMU No results 21124 JY8QFUQ01CJ6HN productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21125 JY8QFUQ01DC0EC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 918 91.24 198/217 nt 90.78 197/217 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggcctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21126 JY8QFUQ01CNYJJ No results 21127 JY8QFUQ01C1T8I No results 21128 JY8QFUQ01B84MI No results 21129 JY8QFUQ01B43QQ productive (see comment) Homsap IGHV3-72*01 F 880 88.74 197/222 nt 87.39 194/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 7 10 11 7.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) ctctggattcatttttagcaatatgccatgaactgggtccgccaggctccaggGgaaggggccggagtgggttggccgtactaaaaacaAaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21130 JY8QFUQ01CRAJJ unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 135 55.56 75/135 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons cctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21131 JY8QFUQ01BFS7D productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21132 JY8QFUQ01AO7UV unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 92.41 207/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); cctctgcagcctctggattcattgtcaatagcaactacatgagttgGggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcCccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagancacagcggcccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21133 JY8QFUQ01A6H7V productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDSRHSASGSYSDYW in-frame + gtctggattcaccttcaatagccatggcatgcactgggtccgccaggcgccaggcaaggggctggagtgggtggctgctatttggtttgatggaagtaataaatactatgcagactccgtgaagggacgattcaccatctccagagacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtactactgtgcgagagattcccggcactctgcctcggggagttattccgactactggggccagggaaccctggtcgccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21134 JY8QFUQ01A93RR productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21135 JY8QFUQ01AW74Z unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [2.17.38.11] CARPFSGRWCFDL## out-of-frame + Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 56 of V-REGION: 'AT' (2 nucleotides at position 83 to 84 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'C' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaaATtaaaaagtgatgggagtaCccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctgggggccgtggcaccctggtcactgtctcctcagcatccccgactagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21136 JY8QFUQ01APNW6 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame - cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21137 JY8QFUQ01BAD2S unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1086 99.55 219/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctaagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21138 JY8QFUQ01BBX3M unproductive Homsap IGHV3-30*01 F 914 91.28 199/218 nt Homsap IGHJ2*01 F (see comment) 94 64.15 34/53 nt Homsap IGHD6-6*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREWAASHFDHW# out-of-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ccgctggattcaccttcagtggctttgctttgcactggctccgccaggctccagacaaggggctagagtgggtgggatttacatcatttgatgggagtaacagagactacgcagactccgtgaagggccgattcacgatctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagacctgacgacacggctgtatattactgtgcgagagagtgggcagccagtcactttgaccactgggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21139 JY8QFUQ01AHPQS productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21140 JY8QFUQ01CDO45 No results 21141 JY8QFUQ01B8W70 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 21142 JY8QFUQ01A9N5Z No results 21143 JY8QFUQ01C98E1 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CAREKWFGPPR#GMDVW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaatggttcgggcccccccgacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggccaccctcctccaaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21144 JY8QFUQ01C4RLG No results 21145 JY8QFUQ01C597W No results 21146 JY8QFUQ01ANM82 productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame - tctggattcaccttcagtagctatggcatgcattgggtccgccaggctccaggcaaggggctggagtgggtggcagttatttggtatgatggaagtaataaattctattcagactccgtgaagggccgattcaccatctccagagacaattctgagaacacgctgaatctgcaaatgaacactctgagaagcgaggacacggctgtgtattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21147 JY8QFUQ01AJJLV No results 21148 JY8QFUQ01B8BYJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + cctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21149 JY8QFUQ01B2RPD No results 21150 JY8QFUQ01CVR9F productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 923 91.74 200/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 177 85.42 41/48 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [1.17.38.11] CARVGGTEEFAGMLELDYW in-frame - Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tgtctggattcagtttcagtagctttggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatctggtatgatggaactaataaatattatgcagactccgtgaagggccgattcaccatctcgagagacaattccaagaacacactgtttctgctcatggacagcctgacagccgacgacacggctgtctattactgtgcgagagtcgggggaaccgaggagttcgctggtatgttggaacttgactactggggccaggggaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21151 JY8QFUQ01C2MA8 unknown (see comment) Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 925 90.99 202/222 nt 90.54 201/222 nt 10 7 X 10.7.X [2.17.38.X] null - No rearrangement found in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gtctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagTcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21152 JY8QFUQ01BIG5T unproductive Homsap IGHV4-61*02 F 988 94.14 209/222 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-6*01 F 2 10 7 X 10.7.X [2.17.38.11] CARNPSYSNSHQHCDY## out-of-frame - gtctctggtgcctccatcaacagtggtagttactactggagttgggttcggcagcccgccgggaagggactggagtggattgggcgtatctacaccagtgggagcaccaactacaacccctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactgggggccagggaaccctggtcaccgtctccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21153 JY8QFUQ01CLA30 productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame - cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21154 JY8QFUQ01B43GM productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21155 JY8QFUQ01B3LYN productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 895 90.74 196/216 nt 90.28 195/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.16.38.11] CARDLYGADDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaagggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21156 JY8QFUQ01AZTGY productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARDLTGYSSERNYW in-frame + ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 21157 JY8QFUQ01ASM00 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 881 90.23 194/215 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-9*01 F 3 8 8 X 8.8.X [0.17.38.11] CVSDLAGQKGF## out-of-frame - caggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21158 JY8QFUQ01CFART productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccGaactatggcatgagctgggtccgccaggctccagggaaggggctggagtggggctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21159 JY8QFUQ01AMSFQ productive (see comment) Homsap IGHV1-2*02 F 808 86.85 185/213 nt 85.92 183/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.16.38.11] CARCLWISGTYHFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) ttggatatactttcaccgaccattatgtttactggagcgacaggccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgatttctggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21160 JY8QFUQ01B0VVU No results 21161 JY8QFUQ01BAD9H productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 883 89.5 196/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARKRVPGGTFYGDYW in-frame + gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21162 JY8QFUQ01CINZT productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CVSSPYFYDSNGYW in-frame + ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21163 JY8QFUQ01BH7ZN productive Homsap IGHV3-7*01 F 953 93.52 202/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [1.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame - tctggattcacatttagtaactactggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacntaaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21164 JY8QFUQ01B7AB1 productive Homsap IGHV3-7*01 F 1045 97.72 214/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 12 8.8.12 [2.17.38.11] CVSSPYFYDSNGYW in-frame - gcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21165 JY8QFUQ01AF7Y6 productive (see comment) Homsap IGHV3-7*01 F 967 94.44 204/216 nt 93.98 203/216 nt Homsap IGHJ4*02 F 167 84.78 39/46 nt Homsap IGHD7-27*01 F 1 8 8 6 8.8.6 [1.17.37.11] CSRLLEEW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) ctctggtttcacctttagtaacgattggatggactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaagggagatggaagtgagaaaactatgtagactctgcgaagggccgattcatcatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattactgttcgagactccttgaggaatggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 21166 JY8QFUQ01AKHKD productive (see comment) Homsap IGHV4-34*10 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GAA' (3 nucleotides at position 58 to 60 in the user submitted sequence), (do not cause frameshift); tgtctggtgagtccttcactaattactGactggagctggatccgccagtcccccaggGAAaagggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21167 JY8QFUQ01ARKWX productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [4.17.38.11] CARGAPFYDS (see Functionality comment) in-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21168 JY8QFUQ01A6Z83 productive (see comment) Homsap IGHV3-33*03 F 905 90.83 198/218 nt 89.91 196/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARSDLSMVRDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'CT' (2 nucleotides at position 15 to 16 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); gtctgggattcaccCTtgcagtaTcctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaatgatttggtatgatggaagccttacatattatgaagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctgtttctgcaaatgaatagcctgagagtcgaggacacggctctgtattactgtgcgagatccgacctctctatggttagagatcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21169 JY8QFUQ01C3WEC No results 21170 JY8QFUQ01AD29W productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1022 96.79 211/218 nt 96.33 210/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggagctggagtGgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21171 JY8QFUQ01CNV1W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 856 88.13 193/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARGGVSGASRWGFDHW in-frame - tctctgggattcaccttcagtagttactggatacactgggtccgccaagctccagggcaggggctggtgtgggtctcacgaattgatagttctgcgcgtctcatagcctacgcggactccgtgaagggacgattcaccgtctccagagacaacgccaagaacacggtgtatcttcaaatgaacagtctgagagccgacgacacggctatttattactgtgcaagagggggggtcagtggggcctccaggtgggggtttgaccactggggccagggagccctggtcaccgtcttctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21172 JY8QFUQ01BYIX2 productive (see comment) Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [1.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21173 JY8QFUQ01C0EBJ unknown (see comment) Homsap IGHV3-7*01 F 909 91.24 198/217 nt 8 8 X 8.8.X [1.17.38.X] null - No rearrangement found ctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcatctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattcccccctcagcctacgatccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21174 JY8QFUQ01DWYBM No results 21175 JY8QFUQ01AQNOF productive (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgCaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtaCtttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21176 JY8QFUQ01COYVI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21177 JY8QFUQ01BH6YQ productive Homsap IGHV4-39*03 F 905 90.78 197/217 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [0.17.38.11] CARSITLTVVVMNDAFDVW in-frame - ccggtggctccatcaacagtagaaattattattggggctggatccgccagcccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtcccttaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21178 JY8QFUQ01B3MC1 productive Homsap IGHV3-48*01 F 815 86.24 188/218 nt Homsap IGHJ6*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 1 8 8 8 8.8.8 [1.17.38.11] CVRGAGLDVW in-frame - cctcagggttcagtttcaacaactataacatggcctgggtccgccagactccagggaaggggctggagtgtgtggcatatattagtagtagaagtagtaacagatattacacagcctctgtggagggccgattcaccatctccagagacaatgccaggaattctctgtatctccaaatgaatggcctgagagccgacgacacggctgtatattactgtgtgagaggcgcgggtctggacgtctggggccaagggaccacggtcgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21179 JY8QFUQ01BYV54 productive Homsap IGHV3-7*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame - ctctggattcctttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21180 JY8QFUQ01CK6WG No results 21181 JY8QFUQ01B5PJY No results 21182 JY8QFUQ01A0I1V No results 21183 JY8QFUQ01DGNJ4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARFGPLTRPDYWG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaAatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccaggggaacccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21184 JY8QFUQ01A4GJG unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 930 91.03 203/223 nt Homsap IGHJ4*03 F 78 62.5 30/48 nt Homsap IGHD3-22*01 F 3 8 10 X 8.10.X [1.17.38.11] CATDRPYYKNRCWPTLVLLRYGRFG# out-of-frame + ctctggattcactttcactaacgcgtggatgagttgggtccgccaggctccagggaaggggctggagtgggttgcccgtgttaaaactaagactgacgatggggcaacagactacgctgcacccgtgaaaggcagattccttatctcaagagatgattcaaacaacatactgtatctgcaaatgaacagcctgagaaccgaggacacagccatgtactactgtgccacagatcggccttactacaaaaatcgctgctggccgactctggtattactacggtatggacgttttgggggcccaaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21185 JY8QFUQ01CEQCM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVKGWNYHSATFGFDYW in-frame + ctctggattcacctttagtgactatgccataagctgggtccgccaggctccaggaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21186 JY8QFUQ01BYPG8 unknown (see comment) Homsap IGHV4-61*02 F 893 89.59 198/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaagggggatagtagtggaccctggaatgactactgggggccagggaatcctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 21187 JY8QFUQ01B1RCH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDRVVLMVHAMS#DFW out-of-frame - tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcgggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccctgaaccggtgacggtgtcgtggaactcag 21188 JY8QFUQ01BEEWM unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 900 90.78 197/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD5-12*01 F 3 8 8 X 8.8.X [1.17.38.11] CGKQLGAHKGADY# out-of-frame + ctctggattcacctttagtagttctggcatgtattgggcccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtgatgccacaaattacgcagactccgtgaagggccggttcaccatctccagagacaactccatgaacacactgtatctgcaaatgaacagcctgggaaccgatgacacggccttatattactgtggaaagcaattgggggcccataaaggggctgactactggggccagggaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21189 JY8QFUQ01AOGKG productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 936 92.63 201/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-8*01 F 3 8 7 15 8.7.15 [2.17.38.11] CTRELRVAAARDGVDIW in-frame - cgcctctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttacttatcctgatggtactacatactatggagactccgtgaggggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttagggtggctgctgcgcgtgatggtgttgacatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 21190 JY8QFUQ01B17XY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt 85.71 186/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggGggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacgttccccgaaccggtgacggtgtgcgtggaactca 21191 JY8QFUQ01BF26Z productive Homsap IGHV3-15*06 F (see comment) 750 81.61 182/223 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 10 9 8.10.9 [1.17.38.11] CQSGCSKTDCW in-frame + Low V-REGION identity (81,61% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggcttcagtatagatcacgcctacatgacgtggatacgtcaggctccagggaaggggctggagtgggtcggccgtattaagaagaagtctgatggtgggactgcaacctacgctgcgcccctgagaggcagattcgtcatatccagagatgattcaaagaacacactgtttctggaaatgaacgaccttaaaatcgacgacacaggcgtctattactgccaatcgggttgtagcaagaccgactgctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21192 JY8QFUQ01CMXUF unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 93.72 209/223 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [1.17.38.11] CTTGGGTNYY## out-of-frame + in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaAaaaaatatgctgtatctgcaattgaacagcctgaaAaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21193 JY8QFUQ01BZKEG productive Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CARSGSGSHLDYW in-frame + ctctagattcacctttagtaggttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttagattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttccc 21194 JY8QFUQ01A1QA1 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 784 84.47 185/219 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSGSSEYTRYDAQDVW in-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctgggattcagcttaagttcttatggcatgaactgggtccgccaggctccatggggggggctggagtgggtctcattcattaacagtattagtagttataagtactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaggaacgcactgatattgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagacagcggctcgtccgagtacactagatacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21195 JY8QFUQ01AFVGX unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 889 89.19 198/222 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 3 10 7 X 10.7.X [2.17.38.11] CVRHHYGGSLN#FKYW out-of-frame - stop codons gtctccggtgcctccatcagtagtaatagtcactactgggcctggatccgccagtccccagggaaggtcctggagtggattgggagtctctattatactgggagcaccctctacaacccgtccctcaagagtcgactcaccacatctgtggacacgtccaagaatctgttttccctgaacctgagtgctgtgaccgccgcagacacggctgtatattactgtgtgagacaccactacggtggttctctgaatttttaagtactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21196 JY8QFUQ01DVNY6 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CASLNTHSGPGAERSAFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'C' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); cctctggatttaccttcagtctctatagaatgaactgggtccCgccaggctccagggaagggactggagtgggtctcatccattactagtaccagtagttacatttattatgcagacccagtgaagggccgattcaccatctccagagacaacgccaagaactcattatatctccatatgaacagcctgagagtcgaggacacggctatatattattgtgcgagtctgaacacgcactcgggaccgggggccgaaaggtctgcttttgatatctggggccacgggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21197 JY8QFUQ01CZ5EI productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTKDTFGREDYW in-frame + ctctggattcaccttcagtagatactggatgcactgggtccgccaggctccagggaaggggctggagtgggtcgcacgtactaatgaagatgggagtactaaaaactacgcggactccgtgaagggccgattcaccatcttcagagacaacaccaagaacacactatatctgcaaatgaacagtctgagagacgaggacacggctgtgtattattgtacaaaagacacgtttgggagagaagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21198 JY8QFUQ01AS0OG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + ctctggattcacgtttaggacctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctccggtattggtggtagtggtcgaaccacacactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaacacggtggatctgcaaatgaacagcctgagagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21199 JY8QFUQ01BIHDR productive Homsap IGHV3-9*01 F 850 88.43 191/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARTYGDHDGMDVW in-frame + tctggattcacctttgacgactatggcatgcactgggtccggcaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatctttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21200 JY8QFUQ01AP4T9 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.37.11] CAKDASRYYYNSYCDN## out-of-frame + in FR3-IMGT, from codon 103 of V-REGION: 1 nucleotides (from position 214 in the user submitted sequence), (cause frameshift) cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtatctgcaaatggacatcctgaaacccgaggacacggccgtttattttgcgcgaaagatgcgtctcgatattattataacagttattgtgacaattgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtagaactc 21201 JY8QFUQ01CPJW6 productive Homsap IGHV3-33*05 F (see comment) 747 82.95 180/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21202 JY8QFUQ01BL9W5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 90.48 190/210 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 7 8 12 7.8.12 [X.17.38.11] CARDRLTISALDYW in-frame - ttcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21203 JY8QFUQ01BYW5H productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F (see comment) 773 83.04 186/224 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 10 13 8.10.13 [1.17.38.11] CSTGGPNGYHSTYPW in-frame + Low V-REGION identity (83,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgccttcaatatcaagtggatgagttgggtccgccaggctccggggaaggggcttgagtgggtcggccgcatcaagagcagcgctgatggtgcgacaacagacaccattgagcgcgtgagagacagattcaccatctcaagagatgactcaaaaaatacactgtacttgcacatgaccagcctgagaaccgaggacacaggcatgtattattgttccacaggcgggccaaatggatatcactccacatatccctggggcccggggacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21204 JY8QFUQ01AAWLL unknown (see comment) Homsap IGHV1-8*01 F (see comment) 768 84.58 181/214 nt 8 8 X 8.8.X [0.17.38.X] null + No rearrangement found Low V-REGION identity (84,58% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cggatacaccttcagcagttatgatatcaactgggtgcgacaggccactggacgagggcctgaatggatggggtggatgagccctagcggtggtcatgcaaactatgcccagagattccagggcagaatcaccatgaccagggacacctccacaagcacagccttcttggaactaaacagcctgaaacttgaggatacagccatatattattgtgcgcgaggatccctcgaccaaggtggcctcccccaattntggggccagggcaccctgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtgtccatcgcctgcctggtccagggcttcttcc 21205 JY8QFUQ01DIQG3 productive (see comment) Homsap IGHV3-9*01 F 861 88.18 194/220 nt 86.82 191/220 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [2.17.38.11] CARTYGDHDGMDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 87 of V-REGION: 'C' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); agtctctggattcaccttTtgacgactatggcatgcactgggtccggcAaaggtccagggaagggcctggagtgggtctcaagtatcagttggaacagtgctaagatagactatgcggacgctgtgaagggccgattcaccacatccagagacaacgccaagaactccatCttttttgcaaatgaacagtctgagaaatgacgacacggccttctacttttgtgcaaggacttacggcgaccatgacggaatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21206 JY8QFUQ01C1YXJ productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 997 96.26 206/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFYYW in-frame - tggatacaccttcaccagctactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtggnggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21207 JY8QFUQ01B3VYC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctcggaattctccgtcagtgacagtcacatgagttgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcacgacccagccagatggaacgctggtcgtcgcatgcctggtccagggcttcttcccccag 21208 JY8QFUQ01BIKYR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARGLAVILGGFDYW in-frame - agcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21209 JY8QFUQ01CBFR4 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 953 91.52 205/224 nt 90.18 202/224 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 164 to 164 in the user submitted sequence), (cause frameshift); cctctggattcgctttcagtaatgcctggatgagttgggtccgccaggctccagggaaGggggctggagtgggttgGgccgtattaaaaaggcagttgatggtgggccaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcaAaaaaatacgttgtatctgcaaatgaacagcctgaaaagcgacgacacaggcatttattactgcacctcgaattcctggctcgaccgctggggccagggaacccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcaccagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaaactcagg 21210 JY8QFUQ01AV2A1 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 751 82.95 180/217 nt 82.49 179/217 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD4-17*01 F 2 8 8 12 8.8.12 [1.17.38.11] CARADDYGDYPEFW in-frame - stop codons Low V-REGION identity (82,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); cctctgactcaacattggcaactatgacatgacctgggtccgccaggctcctgggaaggggctggagtgggtctcaagtattggaactactgagggtagctcatattatgcagactccgtgaagggccggttcaccatctccagagacaactcccagactacgcngTtttttggagatgagcagcctgagagacgaggacacggctgtttattactgtgcgagagctgacgactacggtgactaccctgagttctggggccaggggaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccgagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21211 JY8QFUQ01AT3GQ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 846 88.02 191/217 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21212 JY8QFUQ01DAT9F productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1006 95.05 211/222 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 10 7 12 10.7.12 [2.17.38.11] CVRHRRLELLPDYW in-frame - gtctctggtgactccatcagcagtaatagtttctactggggctggatccgccagcccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21213 JY8QFUQ01DH0FR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) tccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21214 JY8QFUQ01DMIT2 unproductive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [0.17.38.11] CARWNNDLDY## out-of-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattgggggccagggaaccctagtcactgtctcttcagcatccccctgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttcccccca 21215 JY8QFUQ01AL791 productive Homsap IGHV3-48*01 F 1085 100.0 218/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 2 8 8 10 8.8.10 [1.17.38.11] CASRLRSSGGYW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgcggaactc 21216 JY8QFUQ01BHSGX No results 21217 JY8QFUQ01AY4W6 No results 21218 JY8QFUQ01CVPJD productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21219 JY8QFUQ01DLNG7 No results 21220 JY8QFUQ01BYC2V productive Homsap IGHV3-11*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARRRDYGDYGDGFDYW in-frame + ctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgcacagcacccccaagatgggaacgtggtcatcgccctgcctggtccagggcttcttcccc 21221 JY8QFUQ01CH2C7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatagtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21222 JY8QFUQ01B3ITN unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21223 JY8QFUQ01BP7FM productive Homsap IGHV3-30*01 F 1053 98.62 214/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-16*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARDRFGDYILGYYFYGMDVW in-frame - ctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcatttgatggaggtaataaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgagagaccgattcggtgactacattttagggtactacttctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21224 JY8QFUQ01AUH73 productive Homsap IGHV3-9*01 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVKDRGSSSKYYFDYW in-frame + cctctggattcacctttgatgattatgtcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggggaagtgctcatatacactatgcggactctgtgaaggaccggttcaccatctccagagacaacgccatgaactccctttatttgcaaatggacagtctgagagctgacgactcggccttgtattactgtgtaaaagatcggggtagcagttccaagtattactttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 21225 JY8QFUQ01BS5QC productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 888 89.55 197/220 nt 89.09 196/220 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 10 7 16 10.7.16 [1.16.38.11] CTNDFSMAVRATHAFHVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccattggtagtagtgcttactactggggctgggtccgccagccccagggaaggggctcgaatggatagggaatatttactatggtggcagcacctactacaacccgtccctcaagaatcgagtcaccatatcggtagacacgtccaagaaccagctcttcctggagctgacctctgtgaccgccgcagacacggctctttattactgtacgaacgacttttcaatggcggtacgtgctacgcatgctttccatgtctggggccaagggacaatggtcgccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21226 JY8QFUQ01ATCXQ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 865 88.58 194/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame + gcctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21227 JY8QFUQ01B9OPE unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt 8 7 X 8.7.X [4.17.38.X] null + No rearrangement found cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaaggggaacccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21228 JY8QFUQ01CHP04 unproductive Homsap IGHV3-74*03 F (see comment) 712 80.82 177/219 nt 79.45 174/219 nt Homsap IGHJ3*02 F 106 68.0 34/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CVRGTTGWRGVDY## out-of-frame - Low V-REGION identity (80,82% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); gcctctggaGttcaacgtcagtggatactggatgcactgGggtccgccaagtgccagGggaaggggctggtatgggtctctaggctttcggatgatgaaattactataacttacgcggactttgtggagggccgattcaccatctccagagacaacgccaggaacgaggtctatctgcaaatgaatgatttgagagtcgacgatacggctgtatacttttgtgtgaggggaaccactggctggaggggggttgactactgggggccaaggcgccctcgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 21229 JY8QFUQ01B3TCU No results 21230 JY8QFUQ01CV5AS productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21231 JY8QFUQ01AQU2C productive (see comment) Homsap IGHV3-48*01 F 985 95.37 206/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21232 JY8QFUQ01BTMWH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 810 86.18 187/217 nt Homsap IGHJ3*01 F 169 82.0 41/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDDGGHMTLDVW in-frame + gtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccagggggacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtctctccggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgttgcgtggaactcag 21233 JY8QFUQ01AHUQ7 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt Homsap IGHJ5*02 F 75 60.78 31/51 nt Homsap IGHD6-25*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKSPLSV#W out-of-frame - ctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21234 JY8QFUQ01CINEB No results 21235 JY8QFUQ01DIZB4 productive (see comment) Homsap IGHV3-33*03 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-19*01 F 2 8 7 15 8.7.15 [1.17.38.11] CARDGGAVAGLDVVDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 101 in the user submitted sequence), (cause frameshift) cgtctggattgcatttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggtttggacgttgtggacgtctggggccaagggaccacggtcaccgtcgcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21236 JY8QFUQ01C0N7A unproductive Homsap IGHV3-48*01 F 1090 100.0 219/219 nt 98.63 216/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [2.16.38.11] CASRLRSSGGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) agcctctggattcaccttcagtagctatagcatgaactgggtccGgccaggctccagggaagggctggagtgggtttcatGacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagccgcctacgtagttccggtgggtactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21237 JY8QFUQ01A5U65 unproductive (see comment) Homsap IGHV3-7*01 F 976 94.91 205/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CVSSPYFL***W#YW out-of-frame + stop codons tctggattcaccttcagtgactactacatgtcgtggatccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtattttctatgatagtaatggttactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21238 JY8QFUQ01DPXQH No results 21239 JY8QFUQ01CQXUW productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 971 94.88 204/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-12*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARYRGYQSYFEYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtCagttactactggagctggatccggcagccccacgggaagggactggagtggattgggtatCatctcttacagtgggggcaccaattacaatccctccctcaagagtcgagtcgccatatcaggagacacggccaagaaccagttctccctgaagctgaactctgcgaccgctgcggacacggccgtgtattactgtgcgcggtataggggttaccagagctactttgagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21240 JY8QFUQ01B7GYB productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 900 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [1.17.38.11] CNTDLGGSWYTFYSDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 59 of V-REGION: 6 nucleotides (from position 89 in the user submitted sequence), (do not cause frameshift) ctctggatacactgtcataaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21241 JY8QFUQ01BFQMJ productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 987 95.77 204/213 nt 94.84 202/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-13*01 F 3 8 7 11 8.7.11 [0.17.38.11] CARGQQLRDFYYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) tggatacaccttcaccagctactatatacactggGgtgcgacaggcccctggacaagggcttgagtggatgggaataatcgaccctagtgnggtgccacaagntacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctatatggagctgagcagcctgagatctgacgacacggccgtgtattactgtgcgaggggacagcagcttcgagacttttactactggggccagggaaccctggtcaccgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21242 JY8QFUQ01BYNNU unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F (see comment) 455 77.42 120/155 nt 76.13 118/155 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 3 X 8 X X.8.X [X.5.38.11] CAREEWDNGGFGA## out-of-frame + Low V-REGION identity (77,42% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'AG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift); cctctggattcgcacgtattgggattgttggtggtaaaaGcagactacgcggacgccgtaaaAGggccgttttcaccatctccagagacaacacaaggaagactctgtatctacaaatgaacagtctgcgacccgaggacacggcggtgtattactgtgccagagaggaatgggacaacggtggtttcggggcctggggcccagggaaccctggtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21243 JY8QFUQ01BQ9K4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.16.38.11] CVKDISRSGCFEYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 46 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift) tctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21244 JY8QFUQ01CNW9W productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21245 JY8QFUQ01AA3GK productive (see comment) Homsap IGHV3-7*01 F 881 90.23 194/215 nt 89.77 193/215 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 7 14 8.7.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) tctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21246 JY8QFUQ01BKLR9 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cggctggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggGggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgccatggcctggtccagggcttcttccc 21247 JY8QFUQ01BYMEG productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDLRARLWHPMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 35 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); tccggattcagtttcagtacttataacatgaattTGgggtccgccaggctccagggaaggGggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21248 JY8QFUQ01A65A5 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1078 98.65 219/222 nt 98.2 218/222 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame + in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccCAgggaagggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21249 JY8QFUQ01AFJ98 No results 21250 JY8QFUQ01CVI77 productive (see comment) Homsap IGHV4-4*07 F 872 89.77 193/215 nt 89.3 192/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD4-17*01 F 3 8 7 14 8.7.14 [1.17.38.11] CARDLPTVTTGALDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'GA' (2 nucleotides at position 72 to 73 in the user submitted sequence), (cause frameshift); tctctggtggctccttcagtaattaccactggagctggatccggaagcccgccgggaaggaactggagtggGAttggggcgtatccatcacagtgggctcaccaactccaacccctccctcaagaatcgagtcgtcgtgtcagtggatacgtccaagaatcagttgtccctggagctgagctctgtgaccgccgcggacacggccgtgtattactgtgcgagagatcttcctacggtgactactggggctcttgatatctggggccaagggacaatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21251 JY8QFUQ01C54HB productive (see comment) Homsap IGHV4-61*02 F 820 86.3 189/219 nt 84.93 186/219 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 69 of V-REGION: 1 nucleotides (from position 117 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 125 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtggGgggtgtcgactacaaccctccctcagggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21252 JY8QFUQ01B56NJ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 808 85.14 189/222 nt 84.23 187/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [2.17.38.11] CARRWARQRLVMDYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'GA' (2 nucleotides at position 70 to 71 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift); gtctctggtgactccatcagtagtactcattactattggggctggatccggcagccccccagggaggggGActggagtGgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21253 JY8QFUQ01C76ZC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 21254 JY8QFUQ01A4ZI3 unknown (see comment) Homsap IGHV4-61*02 F (see comment) 523 70.78 155/219 nt 69.86 153/219 nt 10 7 X 10.7.X [2.17.37.X] null + No rearrangement found Low V-REGION identity (70,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'TCC' (3 nucleotides at position 146 to 148 in the user submitted sequence), (do not cause frameshift); gtctctggtggccCccatcagcagtggtacttactactggacttggatccggcaggccgccggggagggactggagtggatcggacgtgtttatattagtgggagcaccacctacaatccctccctcaagagtcgaatcaccgtcTCCtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21255 JY8QFUQ01CLS9T No results 21256 JY8QFUQ01C2M6O productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDHW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); cctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccCccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgaccactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21257 JY8QFUQ01DURSH productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tctggattcaccttCcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtaGgtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21258 JY8QFUQ01AZKVO productive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 1007 96.74 208/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [0.17.38.11] CASVVGATMDDAFDVW in-frame - Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) ctggaggcaccttcagcagctatactttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggattatccctatgtttggtacagcaaactacgcacagaagttccaggacagagtcacgattaccgcggacgagtccacgagcacagcctacctggagctgagcagcctgagatctgaggacacggccgtgtattactgtgcgagtgtggtgggagccactatggatgatgcttttgatgtttggggccaagggggcagtggtcaccgtctcttcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21259 JY8QFUQ01CBYCK No results 21260 JY8QFUQ01CDVN4 productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.96 198/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 21261 JY8QFUQ01CN25Y productive (see comment) Homsap IGHV3-66*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 7 13 8.7.13 [1.17.38.11] CASVGVGATVAFQYW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 59 of V-REGION: 'GA' (2 nucleotides at position 91 to 92 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcagtgatagttacatgagctgggtccgccaggctccagggaaggggctggagtgggtctcgattatttataggggGAgggtaccacatattatgccgactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctatatcttcaaatgaacaccctgagaggtgaggacacggctctatattactgtgcgagcgtcggagtgggagctacagtcgcctttcaatactggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21262 JY8QFUQ01CME13 productive Homsap IGHV4-39*02 F 956 92.31 204/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.17.38.11] CARRYSWNYERFDPW in-frame + tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggctgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21263 JY8QFUQ01CB9IS unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 851 88.07 192/218 nt 87.61 191/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame - stop codons in CDR1-IMGT at codon 29 of V-REGION: 'TC' (2 nucleotides at position 14 to 15 in the user submitted sequence), (cause frameshift); attctggattcagTCctagccgactttttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21264 JY8QFUQ01CTZS3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 159 to 159 in the user submitted sequence), (cause frameshift); tctgggttcaccttcagtaactcctggatgcactgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaaTcacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21265 JY8QFUQ01BG43D productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21266 JY8QFUQ01DM7BI No results 21267 JY8QFUQ01CHG8T productive (see comment) Homsap IGHV3-7*03 F 864 88.94 193/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F (see comment) 194 83.64 46/55 nt Homsap IGHD3-16*01 F 2 8 8 10 8.8.10 [1.17.38.11] CAREVSDALDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'TG' (2 nucleotides at position 36 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); ctctggattcacgtttagagactattggatgaggtTGggtccggccaggctcctgggaGgggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgcagggccgattcaccatctccagagacaacgacaacaacgtcctgtatctgcaaatgaacagtttgagacccgaggacacggccttgtatcgctgtgcgagagaggtttcggacgctctggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21268 JY8QFUQ01CZW8Y productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame + tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21269 JY8QFUQ01BZ46F productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1052 99.07 213/215 nt Homsap IGHJ6*02 F 283 95.16 59/62 nt Homsap IGHD6-6*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARDRTPYYYHYGMDVW in-frame + tctctggtggctccatcactagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagagatagaaccccgtactactaccactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 21270 JY8QFUQ01AA0WQ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1046 97.29 215/221 nt 95.93 212/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [1.17.38.11] CARLDYTRYFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccCctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21271 JY8QFUQ01BSHS6 unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + stop codons ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggctgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag 21272 JY8QFUQ01AVOZ8 unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CVRG*RWC*FLAKWTTG in-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcagacattggatgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaAaacaagatggaagtcagagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgagggggtagagatggtgttaatttttggcgaaatggactactgggggccagggaatcctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21273 JY8QFUQ01DDNP8 No results 21274 JY8QFUQ01A8FSV productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*04 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [0.17.38.11] CARGFSAWGQDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); tggatttatcttcagtgattatagcatgaattGgggtccgccagactccagggaaggggctggagtgggtctcttccattagtagtcgaagtactttcgaatattacgcggactcagtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21275 JY8QFUQ01DKLDC productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 891 90.32 196/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGFW in-frame + ctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21276 JY8QFUQ01C10NV No results 21277 JY8QFUQ01APZM5 unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 2 10 9 X 10.9.X [1.17.38.11] CTRGSSRWGEI**ELL*A#DFW out-of-frame - stop codons tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgctggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21278 JY8QFUQ01CPQ7T productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame + cctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 21279 JY8QFUQ01CLIFW No results 21280 JY8QFUQ01DCX1U No results 21281 JY8QFUQ01A4HIU productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.37.11] CARDLPAMGKYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 84 of V-REGION: 2 nucleotides (from position 156 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 167 in the user submitted sequence), (cause frameshift) gctctggatttatgctcaggacttatgacatgaattgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagaaatacagattacacatattacgcagactcagtgaggggccgattcaccatctccagagacaacgccgaaatcactattttgcaaatgagcagtctgagagccgaggacacggctctctatttctgtgcgagagatttgccggctatgggaaagtactactatggcatggacgtctggggccaagggaccacggtcaccgtctcctccgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21282 JY8QFUQ01C0DJC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt 94.95 207/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaGggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgattctggggccaagggacagtggtaatgtctcctagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21283 JY8QFUQ01CO9Q7 productive Homsap IGHV3-30*01 F 927 92.17 200/217 nt Homsap IGHJ6*02 F (see comment) 229 85.48 53/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CARVGCRGVSCYSSYHYSAMDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctctggattcaccttcagcacctatactatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcacttatgtcatctgatggaagtgataaatactacgcagactccgtgcagggccggttcaccatctccagagacaattccaagaataccttgtatctgcaattaaatagcctgagaggtgacgacacggctgtgtattactgtgcgagagtgggttgtcgtggtgttagctgctactcttcctaccattactccgcaatggacgtctggggccagggggccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21284 JY8QFUQ01CV7FV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21285 JY8QFUQ01B0DOB productive Homsap IGHV3-48*02 F 963 94.01 204/217 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-3*01 F 3 8 8 20 8.8.20 [1.17.38.11] CARARRTISGVVFIEHYGMDVW in-frame + ctctggattcaccttcaggacccatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcattcattagtagtagtagtggtaccatattttatgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactttatctgcaaatgaacagcctgagagacgaggatgcggctgtgtattactgtgcgagagcccgtaggacgatttctggagtggtttttattgagcactacggtatggacgtctggggcccagggaccacggtctccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 21286 JY8QFUQ01A0Q68 unproductive Homsap IGHV3-72*01 F 967 92.44 208/225 nt 91.56 206/225 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD7-27*01 F 2 8 10 X 8.10.X [2.17.38.11] CVRDPFSSRG##W out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'C' (1 nucleotides at position 197 to 197 in the user submitted sequence), (cause frameshift); ggctctggattcatcctcagtgactaccacatggagtgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagaaagaaagctaatagttacagtacagaatatgccgcgtctgtgCaaaggcagattctccatttcaagagatgattcaaagaactcactgtatctgcaaatgaacagcctgCaaaatcgacgacacggccgtgtattattgtgtcagagaccccttctcaagtcgggggccactggggccagggaaacctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21287 JY8QFUQ01C8DBD No results 21288 JY8QFUQ01BGN76 unproductive (see comment) Homsap IGHV3-11*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRYLGQLLLL*RSGRL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcactgactactacatgacctggatccgccaggctccagggaAaggggctggagtgggtttcacacattagtagtggtggtagaaccattgcctacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaactcagtgtttctgcaaatgaacagcctgagagccgaggacacggccgtgtattattgtgtgagatatttggggcagctactattactataacggtctggacgtctggggggcaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21289 JY8QFUQ01BNC57 productive Homsap IGHV1-2*02 F 786 85.51 183/214 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD3-16*02 F 2 8 8 15 8.8.15 [0.17.38.11] CARHYCDTNGVCDFDIW in-frame - tggatacagcttcaccgactttcatattcattgggtgcgacaggaccctggacaagggcttgagtggatggggtggaccaaccctaaaaatggcggcacgttcattacgctgaagtttcagggcagggtcactatgtccagggacacgtccatgaccacagtctatatggaaatgagcaggctgagatctgacgacacggccatttattactgtgcgagacattattgtgacaccaacggcgtctgtgattttgatatctggggccaggggacaaaggtcatcgtctctttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21290 JY8QFUQ01B9RRQ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 999 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21291 JY8QFUQ01BYGEB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21292 JY8QFUQ01BY5VZ productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD4-17*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARTSSREITDYW in-frame - cctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtggtacatactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaattcactgtttctgcaaatggacagcctgagagtcgaggacacggctctgtattactgtgcgagaacctcgtcgcgggagattacggattactggggccagggaaccctggtcaccgtttcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 21293 JY8QFUQ01DCKYB unproductive (see comment) Homsap IGHV3-66*02 F 931 92.59 200/216 nt 91.67 198/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [2.17.38.11] CALTYQRRDKYDSSGYY#FDYW out-of-frame - stop codons in FR2-IMGT at codon 41 of V-REGION: 'T' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'AGG' (3 nucleotides at position 80 to 82 in the user submitted sequence), (do not cause frameshift); gcctctggattcaccgtcagtagtaagcacatgaactTggggccgccaggctccagggaaggggctggagtgggtctcaAGGttactttacagcggtggtagtatatactacccagactccgtgaagggccgattcaccatctccagagacaactccaagaccaccctgtatcttcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgctaacctaccagaggcgggataagtatgatagtagtggttattacttttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 21294 JY8QFUQ01BZYBZ productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 1 8 8 13 8.8.13 [1.17.38.11] CARHRAGDSNHFDDW in-frame - ttctggttacgattttgccagacattggatcggctgggtgcgccagacgcccgataaaggcctggagtggatggggatcatctatcctggtgactctgatactagatacagcacgtccttccaaggccaggtcactatctctgccgacaagtccatcagcaccgtctacttgcagtggaatagactgcagacctcggacagcgccatatactactgtgcgagacaccgggcgggggactccaaccactttgacgactggggcccgggaacccaggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21295 JY8QFUQ01CCQ32 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 920 90.95 201/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 10 7 15 10.7.15 [1.17.38.11] CARGSWCTNGVCLLDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tctctggtggctctgtcagcagtaacgttcacttttggggctgggtccgccagcccccagggaaggggctggagtggattgggagtgtctatcatagtggaagcacctactacaaccCcgtcactcaagagtccagtcaccatctccgttgacacgtccgagaaccaggtctccctgaagctgagctctgtgaccgccgcagacacggctgtgtactactgtgcgaggggttcatggtgtactaatggtgtttgccttcttgactattggggccagggaattctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgctggtccaggcttcttccc 21296 JY8QFUQ01CB4CO unknown (see comment) Homsap IGHV1-18*02 (F) (see comment) 492 71.64 144/201 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [X.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (71,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. ggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggcctggagtggatgggatgggtcagcggttataatgataaatccaactatgcacagaagttcaaagacagaattatcatgaccacagacatatcaacgagctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21297 JY8QFUQ01C2M7Y productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame + ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatttccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21298 JY8QFUQ01BE4AN productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 907 92.02 196/213 nt 91.08 194/213 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 2 9 7 11 9.7.11 [X.17.38.11] CARASTLRYLDRW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'C' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ggtggctccatcagcagtgataattggtggagttgggtccgccagcccccaCgggaagggactggaatggattgGgggaaatatatcatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccctagacaagtccaagagtcaattcttcctggagctgaggtctgtgaccgccgcggacacggccgtatattattgtgcgagagcctccacactacgatatcttgaccgctggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21299 JY8QFUQ01CQYMO productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 812 85.52 189/221 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-13*01 F 3 10 7 16 10.7.16 [1.17.38.11] CARRWARQRLVMDYFDYW in-frame - tctctggtgactccatcagtagtactcattactattggggctggatccggcagcccccagggaggggactggagtgggttgggagtatccactacactgggagcacctactacaactggtccctcaagcatcgagtctctatatcggtggacacatcgagtaaccagttctccctgaggttgaggtctgtgaccgccgctgacacggctgtatactactgtgcgagacgatgggcgaggcaacggctggtcatggactactttgactactggggccagggaatcgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21300 JY8QFUQ01AYQIF productive (see comment) Homsap IGHV3-7*01 F 926 92.56 199/215 nt 91.63 197/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 7 8 6 7.8.6 [1.17.38.11] CVKSIDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 21 in the user submitted sequence), (cause frameshift) tctggattcacttttagcagttttggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaatataaAagtgggatggaagtgataaaaagtatatggactttgtgaagggccgattcaccatctccagagacaacgccaagaattcactatatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtgaaaagcattgactcctggggccagggaaccctggtcaccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21301 JY8QFUQ01CVIQ7 No results 21302 JY8QFUQ01CUQ02 productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 21303 JY8QFUQ01BSHHE productive Homsap IGHV3-7*01 F 955 93.15 204/219 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSDFYSTGHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ggctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21304 JY8QFUQ01BYEW8 productive Homsap IGHV3-30*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F (see comment) 202 80.65 50/62 nt Homsap IGHD2-2*01 F 2 8 8 14 8.8.14 [1.17.38.11] CVREGRGTAAYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcaccttcagtagctatgctatgcactgggtccgccagactccaggcaagggactagagtgggtggcagttatatcatatgatggaagtgactacgactacgcaggctccgtgaagggccgattcaccatctccagagacagttccaagaacatgctgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtatcactgtgtgagagagggtcgtggtaccgccgcctacggtctggacgtctggggccgagggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggctcaaggactacttccccggaaccggtgacggtgtcgtggaactca 21305 JY8QFUQ01CS6TS productive Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.38.11] CVKDMVAGQGLLSRFDHW in-frame + Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21306 JY8QFUQ01BW0VC productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*17 F 959 93.58 204/218 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 14 8.8.14 [1.17.38.11] CATDRKYSGVRGDDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcaccttcaggaactatgctatgcactgggtccgccaggctcctggcaaggggctagaatgggtggcttttatatcatatgatggaagtagtcaatactacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacactttatctgcaaatgaacagcctgagaggtgacgacacggctgtgttttactgtgcgacggaccggaaatatagtggtgtacgaggcgatgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21307 JY8QFUQ01B8JXV productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21308 JY8QFUQ01BVHS5 productive (see comment) Homsap IGHV3-69-1*02 P 919 93.33 196/210 nt 92.38 194/210 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-20*01 F 3 8 7 10 8.7.10 [1.16.38.11] CARDDKWAFDYW in-frame - Potentially, because of detected insertion/deletion however the closest V is a pseudogene in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 3 nucleotides (from position 76 in the user submitted sequence), (do not cause frameshift) tctggattcaccttcagtgactacagcatgaactGgggtccgccaggctccagggcaggggctggagtgggtctcatatagtcgcggaagaaccacatactacgcagactctgtgcagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgacagccgaggacacggctgtttattactgtgcgagagatgataagtgggcatttgactactggggccagggaaccctggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21309 JY8QFUQ01BM4S8 unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 96 55.91 52/93 nt 54.84 51/93 nt 8 X X 8.X.X [17.6.X.X] null - No rearrangement found in FR1-IMGT, from codon 17 of V-REGION: 24 nucleotides (from position 107 in the user submitted sequence), (do not cause frameshift) gggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttgggggctggtcggggatgctgggggccgccggatccaactccagtagtaaccagtcatggagccaccagaga 21310 JY8QFUQ01DMLBM productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [2.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'T' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtttcggggttcaccgtcagtagcaagtacatnacctgggtccgccaggctccggggaagggactggagtctgtctcTggttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 21311 JY8QFUQ01B1BO5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame - cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21312 JY8QFUQ01C39IC productive Homsap IGHV3-48*01 F 918 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CTRQTGNYYYFGVDVW in-frame - ctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggaattcactgtatctgcaaatgaacagcctgagagccgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21313 JY8QFUQ01CS9LF productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21314 JY8QFUQ01C7L9L productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21315 JY8QFUQ01BJJ22 No results 21316 JY8QFUQ01AGZC5 productive Homsap IGHV3-48*03 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + ctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21317 JY8QFUQ01AFOO8 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 907 90.09 200/222 nt 89.19 198/222 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [2.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'C' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagtccccagggaaGggggctggagtggattCgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21318 JY8QFUQ01AC68M unproductive (see comment) Homsap IGHV1-2*02 F 813 86.92 186/214 nt 86.45 185/214 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [0.16.38.11] CARCLWISGTYHFDFL# out-of-frame - stop codons in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ttggatatactttcaccgaccattatgtttactggatgcgacaggccctggacaaggccttgagtggatgggatggattaaccctcaaagtggtggcacaaactatgcactgaaatttcagggcagggtcaccatgaccacagacacgtccaccagcacagtgtacatggatctgagtggactgaattctgacgacacgggcgtgtattactgtgcgcgatgtctctggattagtgggacctatcactttgattttctgggggccagggaaccctagtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21319 JY8QFUQ01ADEK7 unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*01 F or Homsap IGHV3-30-3*03 F 819 86.64 188/217 nt 86.18 187/217 nt Homsap IGHJ6*02 F (see comment) 157 72.58 45/62 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDQRDYDYIYYY#GMDLW out-of-frame + Other possibilities: Homsap_IGHJ5*01 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); ctctggattctccctcaggaatcatgctatgcactgggtccgccagactccaggcaagggactcgagtgggtggcagttatctcatttaatggacgaaggaagtattatgcagacttcgtgaagggccgattcaccatcaccagggacaattcccagaacactctgtctctgcaaatTgaatagcctgggaactgaggacacggctgtctattactgtgcgagagatcagcgtgactacgattacatctactattacggggatggacctctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21320 JY8QFUQ01B9UZ4 productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame - tggttacacctttactacctatggcatcagctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggaaatacaaactctgcacagaagttccaggacagagtcaccctgaccacagacacatccacgagcacagcctacatggagctgaggaacctgagatctgacgacacggccgtgtattactgtgcgagagtaattcggaccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21321 JY8QFUQ01BLYFX productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1070 100.0 215/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*02 F 2 8 7 16 8.7.16 [1.17.38.11] CASANYDYVWGSYRYDYW in-frame - tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgtttgggggagttatcgttatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21322 JY8QFUQ01A1U87 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21323 JY8QFUQ01B35H5 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21324 JY8QFUQ01B2P9A productive (see comment) Homsap IGHV3-7*02 F 913 91.67 198/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 7 8 14 7.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctagattcacctttaatgttactggatgagttgggtccgccaggctccaggaaaagGggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21325 JY8QFUQ01A4ENF productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGAGAEGKGGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaAaaaagtatggcatgaactggctccgccaggctccagggaaggggctggagtgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21326 JY8QFUQ01DIY92 productive Homsap IGHV3-7*01 F 918 91.71 199/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame + ctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21327 JY8QFUQ01BUWWW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - cctccggattcacctttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21328 JY8QFUQ01AT51K productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 876 90.19 193/214 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 141 77.08 37/48 nt Homsap IGHD5-24*01 ORF 1 8 8 9 8.8.9 [0.17.38.11] CARGMATAESW in-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tggaatcaccttcagcagacatagcatgaactgggtccgccaggctccagggaaggggctggaatgggttgtatatattagcggtagcagcagtgccatattctacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21329 JY8QFUQ01BQ499 productive Homsap IGHV1-3*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21330 JY8QFUQ01A4GNO No results 21331 JY8QFUQ01ALGGP productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [1.17.38.11] CVRDRSGQAVGYW in-frame + cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaa 21332 JY8QFUQ01CJGZE unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1003 94.22 212/225 nt 93.78 211/225 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD1-26*01 F 1 8 10 X 8.10.X [2.17.38.11] CTTGGGTNYY## out-of-frame - in FR3-IMGT at codon 83 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); acctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcCaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactgggggccagggaaccctggttaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21333 JY8QFUQ01B2XE6 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F or Homsap IGHV4-55*03 P 815 86.24 188/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 9 7 15 9.7.15 [1.17.38.11] CTSREHAFSGQFTGDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TCA' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tgtctggtgtctccgtcaccagcgTCAgtcactggtggacctgggtccgccagcCccccagggaagggactggagtggattggagaaatctattattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgcttttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagacgcacagcggcccctggggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21334 JY8QFUQ01BVCQ0 unknown (see comment) Homsap IGHV2-5*02 F 1134 96.31 235/244 nt 10 7 X 10.7.X [9.17.38.X] null - No rearrangement found gaccctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcattttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcanacttttcggtgactacccccatatggtatggacgtctgggggccaaggggaccacggtcaccgtctccctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21335 JY8QFUQ01AJPAA No results 21336 JY8QFUQ01A79UO productive Homsap IGHV3-48*01 F 867 89.72 192/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [0.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame - tggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21337 JY8QFUQ01C07L6 unproductive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 999 95.85 208/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD4-23*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVRGGLRWRPPDITTT#YGLDVW out-of-frame - ctctggattcaccttcaggagttatatcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtagtagtggtattatcatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaggacacggctgtgtattattgtgtgagagggggactacggtggcgacccccggacattactacgacccctacggtttggacgtctggggccaagggaccacggtcaaagtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21338 JY8QFUQ01BZLF1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 993 96.26 206/214 nt 95.79 205/214 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-3*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARGYDFWSTYRGYNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'CTA' (3 nucleotides at position 77 to 79 in the user submitted sequence), (do not cause frameshift); ctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggCTAtcatcatcttacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgaactctgtgaccgctgcggacacggccgtgtattattgtgcgagaggttacgatttttggagtacatatcgtgggtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21339 JY8QFUQ01A1G6Q unproductive Homsap IGHV3-7*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CVRGRDGVKFWRNGLL# out-of-frame - gcctctggattcacctttagcagacattggatgacctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtcagagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgtgaggggtagagatggtgttaaattttggcgaaatggactactgggggccagggaatcctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21340 JY8QFUQ01BWN76 No results 21341 JY8QFUQ01CCLFY No results 21342 JY8QFUQ01B95ZO No results 21343 JY8QFUQ01CCNXP unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 837 87.56 190/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKQKHSYGYY#DQW out-of-frame + ctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaacatagttatggatactacttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21344 JY8QFUQ01BXNR5 No results 21345 JY8QFUQ01C67LB productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - ttcggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21346 JY8QFUQ01B4XPK productive (see comment) Homsap IGHV2-5*02 F 1165 97.94 238/243 nt 97.53 237/243 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 2 10 7 11 10.7.11 [9.17.38.11] CAHRRIRFGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift); accctcacgctgacctgcaccttctctgggttctcactcagcactggtggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcactcatttattGgggatgatgataagcgctacagcccatctctgaagagcagactcaccatcaccaaggacacgtccaagaaccaggtggtcctcacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacaggaggatacgattcggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact 21347 JY8QFUQ01B1H8E productive Homsap IGHV4-61*08 F (see comment) 827 87.44 188/215 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD7-27*01 F 2 8 7 13 8.7.13 [1.17.38.11] CASVRYLGERLFDHW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01B1H8E ; 10 AA in Homsap_IGHV4-61*08) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccctcgggggtttcgcctggagttggatccggcagcgcccagggaagggactggagtggattggacatatctctcacattgcggactccaactatgagccctccctcaagagtcgactcaccatgtcagtagacgcgtccaagaaccagatctccctgaaactgacctccgtgaccgctgcggacacggccgtctattactgtgcgagcgtgcgctatctcggagaacggctattcgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 21348 JY8QFUQ01C7TH3 unproductive Homsap IGHV3-66*02 F 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [2.17.38.11] CAKFGGYWRVEQPHLLF#W out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); agcctctggattcaccgtcagtagcagcttcatgacttgGggtccgccaggctccaggaaAagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaatttggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21349 JY8QFUQ01CWFJA productive (see comment) Homsap IGHV3-9*01 F (see comment) 779 84.4 184/218 nt 83.94 183/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'A' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggAcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21350 JY8QFUQ01CRUJQ productive Homsap IGHV3-33*03 F 878 89.45 195/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CTRDIGERYSYW in-frame - cctctggattcaacttcggtgactactacatgaactggatccgccaggctccaggcagggggctggagtgggtggcaattatatggcatgatggaaccaataaatactatgcagactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgagcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21351 JY8QFUQ01BFSIG unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcacctttaacagccatgccatgagttgg 21352 JY8QFUQ01CK6XG unknown (see comment) Homsap IGHV1-2*02 F 880 90.61 193/213 nt 89.67 191/213 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [X.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 42 of V-REGION: 'A' (1 nucleotides at position 35 to 35 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); ggatacaccttcactgactactttatacactgggAtacgccaggcccctggacaaggccctgagtggatggGggtggatcaacgctaacagtggtgccacagagtatgcacagaggtttcagggcagggtcaccatgaccagggacacgtccatcaccacagcctacatggacttgagcagtctgagatctgacgacacggccgtctattattgtgcgagactagtcccccacacgagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21353 JY8QFUQ01DI5CP productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 903 91.59 196/214 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame + ttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21354 JY8QFUQ01C7LW0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRQLGFGDLFRFDPW# out-of-frame + in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggatacagttttaacagttatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggGggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21355 JY8QFUQ01CDTNX productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 900 90.32 196/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD6-19*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDKSAVLGTSELDAFDVW in-frame - ctctggattcaccttcagaagttctgcccttcactgggtccgccaggctccaggcaagggcctggagtgggtggcagtaacatcatatgatggaggtgataaatcctacgcagactccgtgaagggccgattcaccatctccagagacaactccaagaacacgctatatctgcgaatgactaacctgagacctgaggacacggctgtctattactgcgcgagagacaagtcggcagtgcttggtacgagtgagctggatgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21356 JY8QFUQ01CLMGG productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*06 F 921 90.58 202/223 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD2-21*01 F 2 8 10 8 8.10.8 [1.17.38.11] CTSNSWLDRW in-frame - ctctggattctctttcagtaatgcctggatgaattgggtccgccaggctccagggaaggggctggaatgggttggccatattaaaagggaaattgatggtgggataacaaactacgctgcacccgtgaagggcagattctccatcgcaagagatgattcaaagaatatgatgtatttgcaaatgaacagcctgaacaccgaggacacaggcgtgtattactgtacctcaaattcgtggctcgaccgctggggccagggaacccccgtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21357 JY8QFUQ01CJJ9D unproductive (see comment) Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKARIYFLWFGELFP#FDYW out-of-frame - stop codons cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctattttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21358 JY8QFUQ01CVGC8 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 764 84.19 181/215 nt 83.72 180/215 nt Homsap IGHJ6*02 F (see comment) 175 75.81 47/62 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CAREKRFGPPH#GMDVW out-of-frame + Low V-REGION identity (84,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 96 of V-REGION: 'C' (1 nucleotides at position 189 to 189 in the user submitted sequence), (cause frameshift); gttatgggttgaccgtcggtgccgaccacatgtactgggtccgccaggctccagggaaggggctgaagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaggggccgattcaccatctccagagacaactcgaggaacactgtgtatcttcagatggagagactgagcCcccgaggacacggccgtctactactgtgcgagagaaaagaggttcgggcccccccacaggcatggacgtctggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtccaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21359 JY8QFUQ01CEJ1C productive Homsap IGHV3-7*01 F 943 93.02 200/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 22 8.8.22 [0.17.38.11] CVRDRFYDSSGYEFGELGDYSDHW in-frame - ctggattcacatttagtaactactggatgagctgggtccgccaggntccagggaaggggctggagtgggtggccaacntaaagaaagatggaagtgagaagtactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagaatacattgtatctgcaaatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgattttatgatagtagtggttatgagtttggggaattgggggactactctgaccactggggccagggaacccaggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21360 JY8QFUQ01CRULS productive (see comment) Homsap IGHV4-61*02 F 888 89.55 197/220 nt 88.64 195/220 nt Homsap IGHJ4*01 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-22*01 F 3 10 7 11 10.7.11 [1.16.38.11] CARAREFLTFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgcctccatcaacaatgatactttctactggaactggatccggcagccgccgggaagggactgcagtggattgggcgtCatgtatgccagtgggaccactaactacaacccctccctcaagagtcgagtcaccatgtcagtagtcacgtcaaagaatcaattttccctgaagttgagttctgtgaccgccgcagacacggccatttactactgtgcgagggcccgagagtttctcacctttgactcctggggccaaggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21361 JY8QFUQ01CH1SK unproductive (see comment) Homsap IGHV3-48*01 F 896 90.37 197/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CARESTWEFYS#DSW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) cctctggattcagtttcagtgactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagttctagtagtaccctatattatgcagactctgtgaagggccgattcaccgtctccagagacaatgacaagagttctctgtatctgcaaatgaccggcctgagagccgaagacacggcgacttattactgtgcgagagagtcgacgtgggaattttactcctgactcctggggcccggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21362 JY8QFUQ01B63GH productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21363 JY8QFUQ01C9AAJ productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKEQEPHGHYVGTDYW in-frame - cgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttgtctcatttgatggaattcttgaacactatgcagactccgtgaagagccgattcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggccgtgtattcctgtgcgaaagaacaagaaccacatgggcattatgttggaactgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21364 JY8QFUQ01DNFZU productive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21365 JY8QFUQ01AXVR3 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARAGASDYW in-frame + cctctggattcaccttcagtagctactggatgcactgggtccgccaagctcccgggaaggggctggtttgggtcgcacgtattagtgatgatgggagtagctccacctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaaaaacacggtgtatctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagcgggggcctctgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21366 JY8QFUQ01C2JVO productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 932 92.2 201/218 nt Homsap IGHJ6*02 F 202 80.65 50/62 nt Homsap IGHD3-16*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARHNYGNEKYIMDVW in-frame + gttttggatacaactttgccacctattggatcggctgggtgcgccacatgcccgggaaaggcctggaatggatggggatgatctttgctggtgactctgacaccagatacagtccgtccttccgaggccaggtcaccatgtcagccgacaagtccatcaacaccgcctacctgcagtggagcagcctgatggcctcggacaccgccatatattactgtgcgagacataattatggaaacgagaagtacattatggacgtctggggccaggggaccacggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21367 JY8QFUQ01BV67Z productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); gttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgGggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21368 JY8QFUQ01B9CT3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame + cctctggattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcgcaactattatttatagtggcgatagtacatactacgcagactccgtgaggggccggttcaccatctccaaagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21369 JY8QFUQ01AT8VL No results 21370 JY8QFUQ01BA09M unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 964 93.61 205/219 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 78 62.5 30/48 nt 8 8 X 8.8.X [2.17.38.11] CARGLAVILGGFGPY (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION gcctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttggaccgtactggggccaggaacctgctcaccgtctcctcagcatccagccaaggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21371 JY8QFUQ01DIWX1 productive Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [1.17.38.11] CVKGRGYNDYGLDYW in-frame + Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21372 JY8QFUQ01B3VEO productive (see comment) Homsap IGHV3-72*01 F 971 92.86 208/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 10 11 8.10.11 [1.17.38.11] CITSFGGRSLAYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); cctctggattcaccttaagtgatcactacatggactgggtccgccaggctccaAgggaaggggctggagtgggttggccgtactaaaaacaaagctaacggttacactacacactacgccgcgtctgtgagaggcagattcattctttcaagagacgattcaaagaactcagtgtatctgcaaatgaacagcctgaaaatcgaggacacggccgtctattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21373 JY8QFUQ01BIGTS unproductive Homsap IGHV3-11*01 F 806 85.78 187/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 79 62.0 31/50 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDRRPWSFDAFDV## out-of-frame + cctctggattcaccttcagggactactatatgagttggattcgcctagcacctgggaaggggctggagtgggtttcatatattagtggtaatgtgtttaccaaacactacgcagactctgtgcagggccgattcaccatctccagggacaacgacaataagacagtctatctacagatggacaacctgagagccgcagacacggccatgtattactgtgcgagagacaggcgcccatggtcttttgatgcttttgatgtctggggccgggggcacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21374 JY8QFUQ01C85UX productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggatcaccctttggttattGatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21375 JY8QFUQ01A3PPQ unknown (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 883 89.5 196/219 nt 89.04 195/219 nt 8 8 X 8.8.X [2.16.38.X] null - No rearrangement found in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) gtgttcgggattcgcttttaccacgtactggatcggctgggtgcgccagatgcccgggaaggcctggagttgatgggaatcatctttcctggtgactctgaggccagatacagcccgtccttccaaggccaggtcaccctctcagccgacacgtccaccaccaccgtctatctgcagtggagcagtctgaggacctcggacaccgccgtgtattactgtgcgagacttgggcaactcgctcttgactactgggggcgagggaaccctgattttccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21376 JY8QFUQ01CZVBC productive Homsap IGHV1-2*02 F 867 89.72 192/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [0.17.38.11] CARGFYGDHFDSW in-frame + tggatacatcttcaccggctactatttgcactgggtgcgacaggcccctggacaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccgtcagcacagtgtacgtggaggtgaggaggctgagatctgacgacacagctctttatttctgtgcgagaggcttttacggtgaccactttgactcctggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21377 JY8QFUQ01CN8NE unproductive Homsap IGHV3-7*01 F 841 87.96 190/216 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - tctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21378 JY8QFUQ01AT762 No results 21379 JY8QFUQ01A157B unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 473 68.35 149/218 nt 67.89 148/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found stop codons Low V-REGION identity (68,35% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); cctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaaGgggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccagggcacccaggtcaccgtctcctcagcatcccccgaccagccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21380 JY8QFUQ01ABR1Q productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame - ctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21381 JY8QFUQ01A3XGI No results 21382 JY8QFUQ01ACEIN productive Homsap IGHV3-9*01 F 981 94.5 206/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame - cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccngagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21383 JY8QFUQ01CJTOK productive (see comment) Homsap IGHV4-59*03 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-21*02 F 3 8 7 15 8.7.15 [1.17.38.11] CARGRTVVTVIDYMDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); tctctggtgactccattagcggttactattggacctggatccggcaaacccccaggaaAAgggactggagtggattggaaatatccactacagtgggagcaccaagtacagtccctccctcaagagtcgagtcaccacatcactcgccacgtccaagaatcaattcgccctgaagttgacctctgtgaccgctgcggacacggccgtctattattgtgcgagaggacgaacggtggtgactgttattgactacatggactactggggtcagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21384 JY8QFUQ01CAL28 unknown (see comment) Homsap IGHV3-72*01 F 889 89.19 198/222 nt 88.29 196/222 nt 8 10 X 8.10.X [1.16.38.X] null + No rearrangement found in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacAaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagccccccccttatgacggctggggccagggaacccctggtcatcgctctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21385 JY8QFUQ01B8393 No results 21386 JY8QFUQ01BOLT9 unproductive Homsap IGHV1-2*02 F 912 92.06 197/214 nt 90.65 194/214 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGPVSGWYTDYW# out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'AAGAG' (5 nucleotides at position 94 to 98 in the user submitted sequence), (cause frameshift); tggatacaccttcaccgTgctactatctattctgggtgcgacggGgcccctggacaagggcttgagtggatgggatggatcaaccccaaccctAAGAGtgtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactgggggccagggaacccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21387 JY8QFUQ01A3L2A unknown (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt Homsap IGHJ1*01 F (see comment) 25 64.29 9/14 nt 8 8 X 8.8.X [1.17.38.X] null - Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagaggggactatgcttcgggggagtcgaccaaagcgagatacggtctggacgtctgggggccaagggaccacgggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21388 JY8QFUQ01CAIWR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ3*01 F 241 98.0 49/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDVW in-frame + ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtatttctgtgcgagagatactctagaggtagtgtctaatatggatgatgcttttgatgtctggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 21389 JY8QFUQ01AXCSX unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 833 87.16 190/218 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CARRSGRDGG#WFDSW out-of-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggattcacctttgtcgactatgccatgagctgggtccgccaggctccagggaaggggctggaatgggtcgcagatattaatggaagaggtgctgccgcacactacgcagactccgtgacgggccgcttcaccctctccaaagacggttccaagaatacgatgtatctgcaaatgaacaccctgagagacgacgacacggccatatattactgtgcgagacgaagtgggcgtgatggggggctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21390 JY8QFUQ01AZLK8 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 935 93.02 200/215 nt 92.09 198/215 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD5-24*01 ORF 1 8 7 12 8.7.12 [1.17.38.11] CARAPRTATLLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 86 of V-REGION: 'C' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); tctctggcgactccatcagtggtcactactggagctggatcaggcagcCccccagggaagggactgcagtggattggttacatctatcacagtgggagcaccaactacaacccctccctcgagagtcgagtctccatttcagtagacacgtccaagaaccaCgttctccctgaggttgagttctgtgaccgctgcggacacggccgtgtattactgtgcgagagccccgaggacggctacacttctcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21391 JY8QFUQ01BQX6U unproductive Homsap IGHV4-61*02 F (see comment) 881 89.77 193/215 nt 88.37 190/215 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [1.17.38.11] XARQGDSSGPWNDY## out-of-frame + Cys 104 is missing in the submitted sequence this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'TGGTTA' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctccggtggctccatcagtacTGGTTAttactactggagctggatccggcagtccgccgggaagggactggaatggattggGgcgcatgtctgccagaggggacagcaactacaaccCcctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgngcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaact 21392 JY8QFUQ01AM6C9 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 221 97.83 45/46 nt 8 X X 8.X.X [1.5.X.X] null - No rearrangement found cctctggattcaccttcagtagctactggatgcactgggtccccca 21393 JY8QFUQ01AB1VC productive Homsap IGHV3-30-3*01 F, or Homsap IGHV3-30-3*02 F (see comment) 411 80.0 104/130 nt Homsap IGHJ6*02 F 184 77.42 48/62 nt Homsap IGHD3-10*01 F 2 X 5 18 X.5.18 [X.X.38.11] CARDDFYSSGNYGGFGMDVW in-frame + Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcaccttcagtcactatgactccgtgaggggccgattcaccatctccagagacaactccaagaacatgatgtatctgcaaatgaacatcctgagacgtgaggacacggctctttattactgtgcgagagatgatttctattcttcggggaattacggaggcttcggaatggacgtctggggccgagggaccgcggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21394 JY8QFUQ01COJXK No results 21395 JY8QFUQ01BJRNU No results 21396 JY8QFUQ01AKA7I productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-6*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAFSRALTGKWIDYLDYW in-frame + ctctggattcatcttcagcaactactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattactggtgatgggagtaacccaatctacgcggaccccgtgaagggtcgattcaccatctccagagacaacgccaagaacacactatatctgcaaatgaacagtctgagagtcgaggacacggctgtgtattactgtgcctttagtagagcactcacggggaagtggatcgactaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtccgcatggcctggtccagggcttcttcccc 21397 JY8QFUQ01APIK2 productive Homsap IGHV3-7*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame + ctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21398 JY8QFUQ01B17PL No results 21399 JY8QFUQ01BH6X1 productive Homsap IGHV3-74*03 F 828 87.1 189/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame + ctctggattcactttccacacctcctggatgcactgggtccgccaaggtccaggggaggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaagggccggttcacactttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21400 JY8QFUQ01B20H0 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1053 98.62 214/217 nt 98.16 213/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD5-24*01 ORF 2 8 8 11 8.8.11 [1.17.38.11] CARSQGFWYFDLW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 176 to 176 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtcgcatccattagtagtagtagtggttacatatactacgcagactcagtgaagggccgattcaccgtctccagagacaacgccaagaactcactgtatctgcaaAatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagatcgcagggattctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21401 JY8QFUQ01BTQAH productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*05 F or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRDDDTSGHYSLFKYW in-frame + cgtctggattctcctttagtgcatatggcatacactgggtccgccagactccaggcaaggggctggagtgggtggctgttatgtattttgatggagttagaacattttatgcagactccgtgaagggccgattcaccctctccaaagactattccaagaacacggtgcatctgcaaatgaacagcctgcgagccgaggacacggctgtatattactgtgtgagagatgatgataccagtggtcactactctctgtttaaatattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21402 JY8QFUQ01A1QYN No results 21403 JY8QFUQ01CFJ5P productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt 87.56 190/217 nt Homsap IGHJ6*02 F 274 93.55 58/62 nt Homsap IGHD6-19*01 F 1 8 8 18 8.8.18 [1.17.38.11] CANHLCNRGECYSYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift); ctctggactcacctttaacaactctgccatgaGgctgggtccgacaggccccaggtaaggggctggagtgggtctcgactattagtggaacgggatataagacattcgacgcagactccgtgaagggccggttcaccatctccagagataattctaagaacacactatatctgcaaatgaagagcctgagacccgaggacacggccgtttattactgtgcgaaccatctgtgtaacagaggtgaatgctactcctattacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21404 JY8QFUQ01B5F9B unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ3*01 F 196 88.0 44/50 nt Homsap IGHD4-17*01 F 3 8 7 X 8.7.X [1.17.38.11] CASLVTIK*QR*LHVG#FDVW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'TT' (2 nucleotides at position 49 to 50 in the user submitted sequence), (cause frameshift); tggatggtgggtccttcagtaataagtattggagttggattcgccagtTTcccagggaagggggctagagtggattggagaaatcaaccaaagtggaagcaccaactacaatccgtccctcatgagtcgagtcaccatctccatagacacgtccaagatgcagttctccctgaagttgacctctgtgaccgccgcggacacggctgtctattattgtgcgagtttagtgaccattaaatgacaacggtgactacacgtgggctttttgatgtctgggcccaagggacaatggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21405 JY8QFUQ01C4924 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F or Homsap IGHV3-53*03 F 143 65.0 52/80 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 X X 8 X.X.8 [X.X.26.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcacttttagtgactattggatgagttggatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21406 JY8QFUQ01CK0PG No results 21407 JY8QFUQ01CUQPV productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 868 89.35 193/216 nt 88.89 192/216 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-22*01 F 3 7 8 15 7.8.15 [1.17.38.11] CARRSNPNAMMAAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ttctggattcagtcctaccgattttggatcggctgggttcgccagctgcccggcaaaggcctggagtggatgggcctcatttatcctggtgactctgagaccagattcaacccgtccttccaaggccaggtcaccatctcagccaacaagtccataaataccgcctacctacagtggagcagcctgaaggcctcggacactgccgtgtattactgtgcgaggcgatccaaccctaatgctatgatggcggcgtttgatatctggggccaagggacaatggtcaccgtttcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtggacggtgtcgtggaactcagg 21408 JY8QFUQ01CMR93 productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - ctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21409 JY8QFUQ01AXOPB unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 964 93.61 205/219 nt 93.15 204/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactgggggccaggggaaccctggtcaccgtctccctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21410 JY8QFUQ01AJZPZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame - ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21411 JY8QFUQ01AVQX9 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F (see comment) 487 68.95 151/219 nt 68.04 149/219 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-8*02 F 3 9 7 12 9.7.12 [2.17.38.11] CAREDIVREGLDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (68,95% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 76 of V-REGION: 'C' (1 nucleotides at position 135 to 135 in the user submitted sequence), (cause frameshift); tgtctggtggctccatcgccacttatcattggtggaacttgggtccgccagacccccgggaagggactggagtggattggggaagtctattatagtcgacagactaattacaacccgtcCcctccagagtcgcgCttgacatttccattgacagtcccaacggtcagttcaccctatatctgagagatgtgaccgtcgcggacacggccgtttattattgcgcgagagaagacattgttcgggagggcctcgaccactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21412 JY8QFUQ01A2O1P unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactanttccccgaaccggtgacggtgtcgtggaactc 21413 JY8QFUQ01CLHAM productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21414 JY8QFUQ01AI9XU No results 21415 JY8QFUQ01B51E2 unproductive (see comment) Homsap IGHV3-48*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARDVPGPK*QL#FDYW out-of-frame + stop codons cctctggattcagcttcagagactatggcatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatacattggtaggattattagtgacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagggacgacgacacggctgtctatttctgtgcgagagatgtcccgggccccaaatgacaactacttttgactactggggccagggaaccctgcttaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggatgggaacgtggtcgtcgcatgcctggctccagggcttcttccccca 21416 JY8QFUQ01BH0GH productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 849 87.0 194/223 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 3 8 8 10 8.8.10 [3.17.38.11] CASFRVLESGYW in-frame - tcaggtctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtgtcctggaaagtggctactggggccagggaaccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21417 JY8QFUQ01DBDMO No results 21418 JY8QFUQ01BW1XA productive (see comment) Homsap IGHV3-9*01 F (see comment) 774 84.33 183/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [1.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 77 of V-REGION: 1 nucleotides (from position 137 in the user submitted sequence), (cause frameshift) cctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatggggactctgtgaggggccgattcacatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21419 JY8QFUQ01B5QA5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 901 90.41 198/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame + acctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg 21420 JY8QFUQ01BXQL7 productive Homsap IGHV3-7*01 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.17.38.11] CARVGYGYRGIYFFDYW in-frame - tctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21421 JY8QFUQ01A4Y84 No results 21422 JY8QFUQ01AEV4J No results 21423 JY8QFUQ01BTAHR productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARKRVPGGTFYGDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtacctatggcatgctctgggtccgccatgttgcaggcaaggGggctggagtgggtggcaactatatcagctgatggacgaaataaatactatgcagattccgtgatgggccgattcgccctctccagagacaaatccaagaacacggattatctgcaaatgaacagcctgagaactgacgacacggctgtatattactgtgcgagaaagagagtccccggggggactttttatggggactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactca 21424 JY8QFUQ01B8N31 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 896 90.37 197/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRSEYSS#NWFDPW out-of-frame + cctctggattcagcctcattgactttagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtgttggtcaaaacatatactacagagactcagtgcggggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatctgagtatagtagttcaactggttcgacccctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 21425 JY8QFUQ01AN8DC productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-19*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKEIAVSGEGALDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); ctctggattcacAgtttagcaactatgccatgagctgggtccgccaggctccagggaaggggccggagtgggtctcagctattactggtcttgatggtagaacattctacgcagactccgtgaagggccgtttctccatctccagagacaattccaagaacacgttgtatttgggaatgaacagcctgagagccgaggacacggccgtatattattgtgcgaaagagatagcagtgagtggtgagggggcgttggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21426 JY8QFUQ01CLC9U productive Homsap IGHV4-61*02 F 848 86.88 192/221 nt Homsap IGHJ5*02 F 192 86.27 44/51 nt Homsap IGHD5-24*01 ORF 1 10 7 14 10.7.14 [1.17.38.11] CARGMATIKTVRFDPW in-frame + tctctggtggctccatgaggagtggaattaattcctggacatggatccggcagcccgccgggaagggactggagtggattgggcgtatctatatcaatggagacaccaactacaatccctccctcaagagtcgggccagcatatcaatggacacgtccaagaaccagttctccctgcacttgacctctgtgaccgccgcagattcggccgtctattattgcgcgagagggatggccacaataaaaacggtccgattcgacccctggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21427 JY8QFUQ01B1YQJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 1008 96.31 209/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CILLYYDSRGVFSTDYW in-frame + ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggcgtgggtctcacgtattaaaagtgatggcagtggcacaaactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagcacgctgtttctgcaaatgaacagtctgagagccgaggacacggctgtatattactgtatactgctttactatgatagtagaggtgtcttttcaaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21428 JY8QFUQ01DU512 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - ctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21429 JY8QFUQ01BWUNI No results 21430 JY8QFUQ01BWKUZ No results 21431 JY8QFUQ01CXTY7 unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 890 88.39 198/224 nt 87.95 197/224 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-14*01 ORF 3 8 10 X 8.10.X [1.17.38.11] CTADVPSPLAQK#DFW out-of-frame - stop codons in CDR2-IMGT at codon 59 of V-REGION: 'T' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); cctctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaaactTttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaaaggctgtatctgcagatggacagcctgagaatcgaggacacagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21432 JY8QFUQ01DNFWY No results 21433 JY8QFUQ01BWMC8 No results 21434 JY8QFUQ01CPZTO No results 21435 JY8QFUQ01B8D69 No results 21436 JY8QFUQ01CYIE3 productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 1001 95.02 210/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 2 8 10 10 8.10.10 [0.17.38.11] CTTLPWEPLDYW in-frame - ctggattcactttcagtaatgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaactagaactgatggtgagacaacagactacgctgcacccgtcaaaggcagattcaccatctcaagagatgattcaaaaaacacattgtttcttcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtaccactcttccttgggagcctctcgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21437 JY8QFUQ01BCXIK productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 877 89.81 194/216 nt 88.89 192/216 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 70 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); tccggattcacctttactaattattggatgcactgggtccgccaagctccaggggagggactggtgtgGggtctcacggactaatgaagatgggagtatcacaaactacgcggactCccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctcagagtcgaggacacggctatatattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21438 JY8QFUQ01BB0UE productive (see comment) Homsap IGHV3-33*04 F (see comment) 703 80.37 176/219 nt 79.91 175/219 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [2.17.38.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 44 of V-REGION: 'C' (1 nucleotides at position 47 to 47 in the user submitted sequence), (cause frameshift); gcatttggattccctttcagcgactatggcatgcactgggtccgccCagactccagacaagggactagaaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21439 JY8QFUQ01A9D9E productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F, or Homsap IGHJ5*02 F 109 70.21 33/47 nt Homsap IGHD5-12*01 F 3 8 8 6 8.8.6 [1.17.38.11] CVSIGHGV in-frame + cctctggattcgcctttaggagtgagtggatgaactgggtccgccaagccccagggaaggggctggagtgggtcgcacacattgacactgatgggagtatcgcagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaatactttgtatctgcaaatggacagtctgagagccgacgacacggctatatattactgtgtaagcattggacacggagtgggcccgggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccg 21440 JY8QFUQ01AXEW2 productive Homsap IGHV3-11*03 F, or Homsap IGHV3-11*05 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*03 F or Homsap IGHV3-69-1*02 P or Homsap IGHV3-7*03 F or Homsap IGHV3-71*01 P 165 68.35 54/79 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-8*01 F 2 X X 19 X.X.19 [X.X.26.11] CATDGVGSTVKLMVMGPFDFR in-frame + ctctggattcgtctttaacaactatgccatgggctggatgaacagcctgagagccgaggacacggccgtttattactgtgcgacagatggagtagggtctactgtgaagttgatggttatgggcccttttgacttcaggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21441 JY8QFUQ01CERJX productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 854 88.84 191/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [0.17.38.11] CAREQLEYYYDNNGPKYW in-frame + ctggattcaccctcagggagtatattatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcaatgatctcacatgatggaagaagtcaagactatgtagactccgtgaagggccgattctccatctccagagacaactccaagaacacactgtatctgcaaatgaacagcctgagagttgaagacacggctgtatatttctgtgcgagagagcaactagaatattactacgataataatggtcctaaatactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaaactca 21442 JY8QFUQ01CWNKI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.74 200/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CGKPIVGATGREMPVSLG in-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagcaactatgccatgaactgggtccgccaggttccaggggaggggctggagtgggtctcagccattagtggcagtggtggtagcacattctacacagacgccttgcagggccgattcaccatctccagagacaattccaagaacacgttatatttgcaaatgaaaagcctgagagccggggacacggccgtgtattactgtgggaagccaatagtgggcgcaacaggtagagagatgcctgtttccctgggggccaggggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21443 JY8QFUQ01AIAJ9 productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21444 JY8QFUQ01CEEGX productive Homsap IGHV3-48*02 F (see comment) 729 81.57 177/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21445 JY8QFUQ01BIVV0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift); cctctggattcacctttagcCacttttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21446 JY8QFUQ01CD286 unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-23*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CARGMATAESW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccagggggacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21447 JY8QFUQ01AFKB3 productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21448 JY8QFUQ01AK2C9 No results 21449 JY8QFUQ01ATARJ unproductive Homsap IGHV3-48*02 F (see comment) 470 84.73 111/131 nt 83.97 110/131 nt Homsap IGHJ5*01 F 102 66.67 34/51 nt Homsap IGHD1-1*01 F 3 X 5 X X.5.X [X.X.38.11] CASGGKERLRSTTGLLSRHGRL# out-of-frame - Low V-REGION identity (84,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); ctctggactcaaccttcagcagctataactctgtgaAagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagtgggggaaaggaaagactacgaagtacgacgggactactatcacggcatggacgtctgggggccaagggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccc 21450 JY8QFUQ01DJLQH unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CTKRLSGRPLVESGAP#FFDDW out-of-frame + stop codons ctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21451 JY8QFUQ01DWRL7 No results 21452 JY8QFUQ01A0Q3Y unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD4-11*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CAKQTIFDYYYYGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggattcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgattttcgactactactactacggtttggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21453 JY8QFUQ01A1LFR No results 21454 JY8QFUQ01B259Y No results 21455 JY8QFUQ01BK210 No results 21456 JY8QFUQ01CO089 No results 21457 JY8QFUQ01DC9LM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 995 95.41 208/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 21458 JY8QFUQ01CBXLR productive Homsap IGHV3-48*01 F 810 86.18 187/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CATDRLRGDKYNFDDW in-frame - ctacggatttgtcttcagtggcactaatatgaattggctccgccaggctccagggaaggggctggagtggatttcacacattagtcacaatagtgaaaccatattctatgcagactctgtgaggggccgagtcaccatctccagagacaatgccaggaactcactgtatctgcacatgagcagcctgagagccgaggacacggcagtatattactgtgcgaccgaccgccttcgtggagataaatacaattttgacgactggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21459 JY8QFUQ01ALDZZ No results 21460 JY8QFUQ01DHXHT productive Homsap IGHV4-39*02 F 920 90.95 201/221 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-17*01 F 3 10 7 14 10.7.14 [1.17.38.11] CARPGARETNNAWVDW in-frame + tctctggtggctccgtcagtaggagtgcctactactggggctggatccgccagcccccagggaaggggctggagtggattgggaccatctattatagtgggaccacatactccaatccgtccctcaagactcgagtcaccatgtccttggacacgtccaagaaccacatctccctgaagctgaattctgtgaccgccgcagacacggctgtttattactgtgcgagacctggggctagggagactaataacgcctgggtcgactggggccagggcaccctggtcaccgtctcctcggcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggccacagcgccctgggctgcctggtcaaggactcacttccccgaaccggtgacggtgtgcgtgaactca 21461 JY8QFUQ01DL7SV unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 842 87.61 191/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKQKS*LW#YYFDQW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); cctctggattcacgtttaaaacacatgccatgagctgggtccgccaggctccaggaaaAGggggctggagtgggtctcaaatatcagtggcagtggtggcacaacaaattacgcggagtccgtgaagggccggttcaccatctccagagacaatgacaagaatatcctgtatctacaaatgaacaccctgagagtcgaggacacggccatatattactgtgcgaaacaaaaatcatagttatggatactactttgaccagtggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21462 JY8QFUQ01CAAAT productive Homsap IGHV3-7*01 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGFYSTGYW in-frame - gctctggattcagctttagttattattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgatgggccggttcaccatctccagagacaacgccaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21463 JY8QFUQ01CMH9Z unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKDQSCIVGPCGFDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtctcggctattagtggaagtggtgCgaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactgggggccagggagcccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaactc 21464 JY8QFUQ01CUW2A productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 831 87.85 188/214 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 15 8.8.15 [0.17.38.11] CAKVYTGAWGDPNFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtacttttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21465 JY8QFUQ01CI9HW productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSASSGYARYDAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggGggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21466 JY8QFUQ01B1X3U productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 18 8.8.18 [1.17.38.11] CSTGPSDLSRDYGDYGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 58 of V-REGION: 'CATGATGGAATG' (12 nucleotides at position 86 to 97 in the user submitted sequence), (do not cause frameshift); atctggattcaccttcagaaactatgccatgcattgggtccgccaggctccaggcaaggggctggagtgggtggcacttatatggCATGATGGAATGtttgatggaagaaatgaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaatacggtgtatctgcaaatggacagcctgagagccgaggacacggctttgtattactgttcgacaggaccctcagaccttagtcgtgattacggtgactacggatttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21467 JY8QFUQ01A6WYW unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 967 92.44 208/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt 8 7 X 8.7.X [5.17.38.11] CARGGPTFMI (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ccgtctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagagggggccccacttttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21468 JY8QFUQ01BU1V2 No results 21469 JY8QFUQ01B42GA productive Homsap IGHV3-48*02 F 886 90.28 195/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21470 JY8QFUQ01A8MB9 productive Homsap IGHV3-7*03 F 869 88.99 194/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + cctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21471 JY8QFUQ01DD9DB productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 822 87.38 187/214 nt 86.92 186/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-10*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKESLVRGVISYYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 86 in the user submitted sequence), (do not cause frameshift) ctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcatctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcaagagacaatttcaataatacattgtatctgcaaatgaatagcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctggttcggggagttatctcgtactactttgatgactggggccagggaaccctggtcaccgtctcctccgcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 21472 JY8QFUQ01BFAOT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKGIVGASMQADWFHPW in-frame - cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccacatatcactgtgcgaaaggtatagtgggagcttctatgcaagccgactggttccacccctggggccaggggaccctgctcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21473 JY8QFUQ01C7525 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 958 93.98 203/216 nt 93.52 202/216 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); tctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagGaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21474 JY8QFUQ01B3U1I productive (see comment) Homsap IGHV4-61*02 F 836 87.91 189/215 nt 86.05 185/215 nt Homsap IGHJ4*03 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 1 8 7 16 8.7.16 [1.17.38.11] CARERSASMGAARELDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'GGTGCC' (6 nucleotides at position 24 to 29 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'CT' (2 nucleotides at position 42 to 43 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'TGGGG' (5 nucleotides at position 102 to 106 in the user submitted sequence), (cause frameshift); tctctggtggccccatcggcagtGGTGCCtactactgggacCTgggatccggcagGcccgccgggaagggattggagtggctcgggcgtgtttatagtggtTGGGGgggatcatcaattacagtccctccctcaagagtcgaatcaccatgtcgatagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttatattactgtgcgagagaacgtagtgcctcgatgggcgctgcgagagaacttgactcctggggccaggggaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21475 JY8QFUQ01AXFZP unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 848 87.33 193/221 nt 84.62 187/221 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CARRHYGEGLFDY## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 75 of V-REGION: 'G' (1 nucleotides at position 139 to 139 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); tctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggGAagggggctggagtggattgggggAtgtccagtatagtgGggagcacctactccaGccccgtccctcaagaggcgGggtcaccatgtctgtggacgtgtccaaaaaGtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21476 JY8QFUQ01CR329 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F (see comment) 755 83.72 180/215 nt 83.26 179/215 nt Homsap IGHJ3*01 F 160 80.0 40/50 nt Homsap IGHD6-25*01 F 2 8 7 X 8.7.X [1.17.38.11] CARGTRYNNGLDA#FDVW out-of-frame + stop codons Low V-REGION identity (83,72% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); tctcgagtgcctccatgatcagttactattggacctggattcggcagcCccccagggaagggactggagtggattggggacatctattcctttggaggcaccagatacaacccgtcccttggcagtcgagtctccatatcactggacacgtccaataatgagttctccctgcaactgaactctgtgaccgctgcggacacggccttatatcactgtgcgagggggacccggtataacaacggtcttgacgctttttgatgtctggggcccagggacagtggtcatcgtctcttcatcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaact 21477 JY8QFUQ01CWYLE productive Homsap IGHV4-59*02 F (see comment) 741 83.18 178/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-16*02 F 2 8 7 11 8.7.11 [1.17.38.11] CARGDSRGLFDLW in-frame - Low V-REGION identity (83,18% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctgggggccccgtgagaagtacttactggaattggattcgacaggccccagggaagggactggagtggattggctatgtctatttcagcgggagcagtctctacaacccctctctgagggggcgagttaacatctctgtggacacgtccaagaaccagttctccctgggtctgagttctgtgaccgctgcggacacggccgtgtatttctgtgcgaggggggattctcgtgggctctttgacctctggggccagggaaccctggtcaccgtctcttcggcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21478 JY8QFUQ01CKA5O unproductive Homsap IGHV3-9*01 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD3-16*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDIGVHMWTIDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); ctctggattcacgtttgatgactatggcatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggcattacttggaatagtggttacataggctatgcggactctgtgAaagggccgattcaccatctccagagacaacgccaagaactccctgtatctacagatgaacagtctcagagctgacgacacggccttgtattactgtgcaaaagatattggggtacacatgtggaccattgactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21479 JY8QFUQ01CYBYH productive (see comment) Homsap IGHV4-61*01 F (see comment) 753 82.73 182/220 nt 82.27 181/220 nt Homsap IGHJ4*03 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 1 10 7 13 10.7.13 [1.17.37.11] CARDGNERLLLFETW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tgtctggtggctccgtcagcagtggaaattcctactggacttggatccgccagtcccccgagaagggactggagtggcttgcatatattcgaaacactgggacaaccaactacaaccctccctcaagagtagactcaccatgtctctggacatgtctaggaatcagttctccctgaggttgaacgatgtgaccgctgcggacacggccatatattactgtgcgagagacggcaatgagaggttattactctttgaaacctggggccgagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21480 JY8QFUQ01DB4C5 productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 818 86.98 187/215 nt 85.58 184/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'C' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'C' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift); ctggatacaccttcaccgactacttcatacactggctgcgacaggccCcctggacaagCgacttgaCgtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21481 JY8QFUQ01COI8H productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F 1058 98.62 215/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD6-19*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDLAGQWLAFDYW in-frame + cctctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatcttcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatttggcgggacagtggctggcatttgactactggggccagggaaccctgggtcaccgtctcctcagggagtgcatccgccccaaccct 21482 JY8QFUQ01ASNKJ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 857 87.78 194/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CAATMNYMSADSTGWYGGG#DYW out-of-frame - stop codons tctctggtggctccatcaataataggctctactactggggctggattcgtcagcccccagggaagggtctggagtggattgggagcatccataatagtgggagcacctactacagtccgtccctcgagagtcgtgtcatcatctccgtagacacgtccaacaagcggttcttcctgaggctgagctctgtgaccgccgcagacacagctatgtactactgtgcggcaacgatgaattacatgtccgccgatagcactggctggtacggcggggggtgactactggggccagggagcctcggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21483 JY8QFUQ01DR4DQ unproductive Homsap IGHV1-3*01 F 961 94.84 202/213 nt 93.9 200/213 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-24*01 ORF 1 8 7 X 8.7.X [0.17.38.11] CARWNNDLDY## out-of-frame - in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 65 of V-REGION: 1 nucleotides (from position 100 in the user submitted sequence), (cause frameshift) tggatacaccttcagtacctatactatgaattgggtgcgccagGgcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattgggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21484 JY8QFUQ01AYFQ1 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 89.4 194/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*01 F 1 8 8 14 8.8.14 [1.17.38.11] CVRQLGFGDLFRFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); ctctggatacagttttaacagttatgccatgacttggGgtccgccaggctccagggaaAGggggctggagtgggtctcaactattagtggcactggtggtaaccaatactacgcagactccgtgaggggccggctcaccatctccagagacaattccaagaacacactatttctgcagatgagcagcctgagagccgaggacacggccgtttattactgtgtgagacaattgggattcggggacttattccggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21485 JY8QFUQ01AV1JS productive (see comment) Homsap IGHV3-7*02 F 942 92.27 203/220 nt 90.91 200/220 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'CT' (2 nucleotides at position 66 to 67 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'GA' (2 nucleotides at position 99 to 100 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 133 to 133 in the user submitted sequence), (cause frameshift); agcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccaggggaagggcCTgggagtgggtggccaacataaaggaagacggGAagttgagagatattatgtggactctgtgaaggGgccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21486 JY8QFUQ01AVLE1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 873 89.4 194/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [1.17.38.11] CSKDTFGREDYW in-frame + ctctggattctccgtcagtaattactggatgcactgggtccgccaggctccaggggaggggctggagtgggtctcacgtattaatgaagatggtagtcggacagactacgcggactccgtgaagggccgattcaccatttacagagacagcgccaagaacacactgtatctgcaaatgaacagtctgagagtcgaagacacggctgtctattattgtagtaaagacacatttgggcgagaagactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 21487 JY8QFUQ01BF5XC unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagGggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21488 JY8QFUQ01A3ZP4 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1055 97.74 216/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [2.17.38.11] CARPYCGGDCHNRGAFDI## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cagcgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctgggggccaagggacaatggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21489 JY8QFUQ01A8GSF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt 85.65 185/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.37.11] CVKDISRSGCFEYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 67 of V-REGION: 'A' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 98 of V-REGION: 1 nucleotides (from position 197 in the user submitted sequence), (cause frameshift) ctctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaAccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgagacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21490 JY8QFUQ01DDCKT productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 991 94.98 208/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame + gcctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccggaaccggtgacggtgtcgtggaactc 21491 JY8QFUQ01BMWQU No results 21492 JY8QFUQ01B3LSL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21493 JY8QFUQ01C0PGJ productive (see comment) Homsap IGHV4-39*02 F 942 91.82 202/220 nt 91.36 201/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.16.38.11] CARRYSWNYERFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 56 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtactaataattactactgggcctggatccgccagccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaaggggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcaggc 21494 JY8QFUQ01CB7X9 productive Homsap IGHV3-11*01 F (see comment) 779 84.4 184/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame - Low V-REGION identity (84,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21495 JY8QFUQ01ACX19 No results 21496 JY8QFUQ01BE1KI productive Homsap IGHV3-48*01 F 851 88.07 192/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtaccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21497 JY8QFUQ01BOCJK No results 21498 JY8QFUQ01DK9PC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 852 87.73 193/220 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD2-8*01 F 1 8 8 19 8.8.19 [2.17.38.11] CAKVFQVSGEHHFYYYGMNAW in-frame - agcctctggattcatctttagtaattatgccatgagttgggtccgccaggccccagggagggggctggagtgggtctcaactatcagtgccaatggagacaacacatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagagcacagtgtatatgcaaatgaacagcctgaaagccgaggagacggccgtctatcattgtgcgaaagtcttccaggtgtctggcgaacatcacttctactactatggtatgaatgcctggggccaagggaccacggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21499 JY8QFUQ01A5JOZ productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 2 8 8 12 8.8.12 [1.17.38.11] CARWRGQQSEMEYW in-frame - ctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21500 JY8QFUQ01BWXYO No results 21501 JY8QFUQ01AP035 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [1.17.38.11] CANELGYCSGG# out-of-frame + cctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaagggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttccccc 21502 JY8QFUQ01A8WHD unproductive (see comment) Homsap IGHV3-7*01 F 968 94.04 205/218 nt 93.58 204/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARVGLWLPRNILL*LL# out-of-frame + stop codons in FR3-IMGT at codon 91 of V-REGION: 'T' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); cctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaaatTgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtggggctatggttaccgaggaatatacttctttgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21503 JY8QFUQ01CBAN4 productive Homsap IGHV3-7*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21504 JY8QFUQ01A23AX productive Homsap IGHV3-11*04 F 1053 98.62 214/217 nt Homsap IGHJ4*02 F (see comment) 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 17 8.8.17 [1.17.38.11] CANNLPPGIEMATIPYDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtggtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagggacaacgccaagaacacgctgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcgaataacctccccccaggaatagagatggctacaattccgtatgactcctggggccagggaaccctggtcaccgtctcctcagggagtgcatccgccccaaccc 21505 JY8QFUQ01DUD1Z No results 21506 JY8QFUQ01B6OPE unproductive Homsap IGHV3-7*01 F 960 93.18 205/220 nt 92.27 203/220 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CVSSPYFYDSNGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 88 to 88 in the user submitted sequence), (cause frameshift); agcctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagGggggctggagtggtggccaagcataaAagcaagatgcaagtgaggaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgtgtgagttcaccgtatttctatgatagtaatggttactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21507 JY8QFUQ01APCSR unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 1003 96.3 208/216 nt 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 1 8 7 X 8.7.X [1.17.38.11] CARDNYGDYW# out-of-frame + in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 95 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21508 JY8QFUQ01CQSMJ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDCDSGECNFDYW in-frame + ctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21509 JY8QFUQ01BXQU2 No results 21510 JY8QFUQ01DN20F unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 781 83.78 186/222 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD5-18*01 F 3 8 10 X 8.10.X [1.17.38.11] CTWGQHWLFSAY#W out-of-frame - Low V-REGION identity (83,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggactcactttcagtgacgcctggatgacctgggtccgccaggttccagggaagggctggagtggggttgcccatattagatggaactctgatgactggaccacagactacgctactcccgtgaagggcagattcaccatctcaaaagatatttcagagaacacgctgtatctacaaatgaacagcctgataagcgaggatacaggcgtttattactgtacctggggacagcactggttattttcggcttacctggggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21511 JY8QFUQ01DGMBL productive Homsap IGHV1-18*01 F 957 94.39 202/214 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-3*01 F 1 8 8 20 8.8.20 [0.17.38.11] CARDHRSGALEWSHHYHGMDVW in-frame + tggttacatcttcacccactatggtatcaactgggtgcgccaggcccctggacaagggcttgagtggatgggatggatcagcgcctacagtggtaacacaaagtatgcacagaaggtccagggcagagtcaccatgaccacagacacttccacgagtacagcctacatggagctgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagatcacagaagcggggctttggagtggtctcaccactaccacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatcccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 21512 JY8QFUQ01CUHW8 unknown (see comment) Homsap IGHV4-4*07 F 818 86.98 187/215 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccaggggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21513 JY8QFUQ01B68NJ productive (see comment) Homsap IGHV3-9*01 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); cctctggatttaactttgatcaatatgccatgtattgggtccgGgcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggcGtatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21514 JY8QFUQ01BT47B unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21515 JY8QFUQ01CF1B0 unproductive Homsap IGHV4-61*02 F 830 86.43 191/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARDTGQTYGRGP#LDYW out-of-frame - tctctggtgcctccataaataggggtaattattactggaactggatccggcagcccgccgggaagggcctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcgggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgtctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21516 JY8QFUQ01B2QKI No results 21517 JY8QFUQ01BRXD7 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F or Homsap IGHV3-7*02 F 105 58.33 49/84 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 21518 JY8QFUQ01CP17D productive Homsap IGHV3-9*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKSGTYSSSSGHFDLW in-frame + cctctggattcaactttaataattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaataatggtaacacagactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagaactgaggacacggccttatattactgtgcgaaatccgggacgtatagcagctcgtccggccactttgacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21519 JY8QFUQ01CUYJY No results 21520 JY8QFUQ01C2M9W productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctactggatgcattGgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21521 JY8QFUQ01CL3ZB No results 21522 JY8QFUQ01DNTEO No results 21523 JY8QFUQ01DFQND unproductive Homsap IGHV4-39*02 F 829 86.76 190/219 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD5-12*01 F 1 10 7 X 10.7.X [1.17.38.11] CARHVVLDNRYSVWPRILDS## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggttttggacaatagatacagtgtctggcctcgtatccttgattcctgggggccagggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21524 JY8QFUQ01A8LB5 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 924 90.91 200/220 nt 90.0 198/220 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 1 8 8 15 8.8.15 [2.17.38.11] CNTDLGGSWYTFYSDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 5 nucleotides (from position 90 in the user submitted sequence), (cause frameshift) gtctctggatacactgtcaTgaaatgcctggatgagttgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaaggtgatggtgtgacaacagaatacgctgcatccgtgaaaggcagattcaccatcacaagagatgactcaaggaacacgttgtatctacaaatgaacagcctgaaaaccgaggacacagccatatattattgcaacacagatctgggcgggagttggtacaccttctattctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21525 JY8QFUQ01BFYP6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1045 97.72 214/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [2.17.38.11] CARDLTGYSSERNYW in-frame - gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21526 JY8QFUQ01AU1DC unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons cctctggattcacctttaccaactatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21527 JY8QFUQ01BLX8G productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.26 206/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARGQQLRDFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactaTtttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgaggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21528 JY8QFUQ01BVDBD unproductive Homsap IGHV3-13*01 F 961 94.84 202/213 nt 94.37 201/213 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD1-1*01 F 2 8 7 X 8.7.X [1.16.38.11] CARGSSKAYNWFD#PG out-of-frame - in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 64 in the user submitted sequence), (cause frameshift) ctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctgagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgaccccctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21529 JY8QFUQ01A3552 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD5-18*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKDWGPNRQMWFGESLW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'GCTGTTGCC' (9 nucleotides at position 94 to 102 in the user submitted sequence), (do not cause frameshift); gcctctggattcacgttcagcagctatgccatgacctgggtccgccagactccagggaaggggctggagtgggtctcaactattcatggcggtGCTGTTGCCggtggcaccacagactacgcggtctccgcccagggtcgattcaccatctccagagacaattccaagagcacactgtatttgcaaatgagcgacctgagacccgaggacacggccctctatttctgtgtgaaagactggggccccaatcggcagatgtggttcggggagagtctctggggccagggaactctggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21530 JY8QFUQ01AIGWB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-10*01 F 3 8 8 17 8.8.17 [1.17.38.11] CAKKNIIIRGLIYNNFDYW in-frame + cctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaaaaaaacattataattcggggacttatttataacaactttgactactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21531 JY8QFUQ01BY21V productive Homsap IGHV3-7*01 F 868 89.35 193/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame + tctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21532 JY8QFUQ01C4VB4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 969 93.64 206/220 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - agcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgatagaacataccacgcagactccgtgcagggccggttcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagccgacgacgcgggcgtatattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21533 JY8QFUQ01BZBYM productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 896 90.37 197/218 nt 89.91 196/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [1.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); cggctggattcaacttccgatcttatgccatgtactgggtccgccaggCccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21534 JY8QFUQ01B1CD9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD1-26*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARPFSGRWCFDLW in-frame + ctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21535 JY8QFUQ01DE4ZI unproductive (see comment) Homsap IGHV4-39*02 F 849 87.0 194/223 nt 86.1 192/223 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD5-12*01 F 1 10 7 X 10.7.X [2.17.38.11] CARHVVFGQ*IQCLASYP*FL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 27 of V-REGION: 'C' (1 nucleotides at position 8 to 8 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); tgtctctCggtgaccccatcggcaacactgcttactcctggggctggatccgccagcccccagggaaggggctggagtggatcgcgactgtacattatgctggcagcacctactacaacccgtccctcaggagtcgagtcaccatctctgtggacacgtccaagaatcacttctccCctgaagctgaattctgtgaccgcctcagacacggctgtatacttctgtgcgagacatgtggtttttggacaatagatacagtgtctggcctcgtatccttgattcctgggggccagggaacccttgtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21536 JY8QFUQ01CQO22 No results 21537 JY8QFUQ01B924O unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 974 93.67 207/221 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSQSRYSWGDFLH## out-of-frame + tctctggtgactccatcagcagtactagttactactggggctggatccgccagcccccagggagggggctggagtggattggaagcatctattatagtgggagcacctcctacaacccgtccctcgagagtcgaatcaccatgtccgtagacatgtccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtttatttctgtgcgcggtcccagagtagatacagttggggtgacttcttacactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgnagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21538 JY8QFUQ01CSWYE productive (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 994 95.83 207/216 nt 94.91 205/216 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [1.16.38.11] CARVGYGYRGIYFFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 210 to 210 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctttagtagctattggatgaactgggtccgccaggctccagggcagggctggagtgggtggccactataaagcaagatggaagtgagaaatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtaGttactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21539 JY8QFUQ01ASX0M productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21540 JY8QFUQ01C9X2Z unproductive (see comment) Homsap IGHV4-61*02 F 883 89.09 196/220 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 10 7 X 10.7.X [1.17.38.11] CARDPQGYL*WW*LPLFCNGRL# out-of-frame - stop codons ctccggtggctccatgagaagtggaagcaactactgggcctggatccggcagcccgccgggaagggactggagtggcttgggcgtatatatgccactgggagcagcaaccacaacccctccctgcagggtcgagtcaccatgtcagtagacacgtccaaaaaccngttctccctgaggctgatctctgtgaccgccgcagacacggccgtgtacttctgtgcgagagacccccagggttatttgtagtggtggtagctgccgctcttctgcaatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21541 JY8QFUQ01CH9K4 productive Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 913 86.42 210/243 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 3 10 7 11 10.7.11 [9.17.38.11] CAHFGPQEHFDFW in-frame - accctcaccctgacctgcgacttctctggattctcactcagcaccaatgtaatgggtgtgggttggatccgccagcccccgggagaggccccagactggctcgctctcatttattgggatgatgataagcgataccggccatccctagagagtagactcaccatcaccaaggacatctccacaaaccaggtggtccttagaatgaccgacatgggccctgcagacacagccacatatttctgtgcacactttggaccacaggagcacttcgacttttggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21542 JY8QFUQ01C7ZJ7 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 887 89.91 196/218 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVAVGMSGWFDPW in-frame + tctctggatttacctttagcagttatgccatgaactgggtccgccaggctccagggaaggggctggtgtgggtctcacgtattaatggtgatggcagtagcacaagctacggggactccgtgaagggccgattcaccgtctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgcgagtcgacgacacggctctatattattgtgcaagaggccgtatagtagcagttgggatgtcaggctggttcgacccttggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaaggtcttcccgctgagccctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21543 JY8QFUQ01A47M7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21544 JY8QFUQ01DK51Z No results 21545 JY8QFUQ01BBRVM unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 940 92.63 201/217 nt 90.78 197/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-3*01 F 2 8 7 X 8.7.X [2.16.38.11] CARGGLEPVDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 44 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 62 of V-REGION: 1 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) gccctctggattcaccttGcantacatactggatgcactgggtcgccaagctccaggaaggggctggtgtgggtctcccgtatcaatcctgatggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggcccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21546 JY8QFUQ01AWVGJ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CTRDIGGRYSY## out-of-frame + in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtGgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21547 JY8QFUQ01BL43C productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARGLAVILGGFDYW in-frame - cctctggattcaccttcagtagttatagcatgcactgggtccgccaggctccagggaagggactggagtgggtctcctccattagtagtaatagtgcctacacagaccacgcagactcagtgaagggccgattcaccatctccagagacaacgacaagaggtcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggctagcagtgattcttggaggatttgactactggggccagggaaacctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21548 JY8QFUQ01BDBP6 unproductive (see comment) Homsap IGHV3-7*01 F 981 94.93 206/217 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDPL*WWWL#GAFDIW out-of-frame + stop codons ctctggattcacctttagtaataattggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacatcaagcaagatggaagtgagaaagtctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacgcactgtttctgcaaatgaacagcctgagagtcgaggacacggctgtgtactactgtgcgagagaccccctataatggtggtggttatggtgcttttgatatctggggccaagggacaatggtcaccgtctctttagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21549 JY8QFUQ01BTB0T productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21550 JY8QFUQ01ASTD9 productive (see comment) Homsap IGHV1-18*01 F 827 87.44 188/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-14*01 ORF 3 8 8 8 8.8.8 [0.17.38.11] CARDRPNEFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 46 to 47 in the user submitted sequence), (cause frameshift); tggttaccccctttaatacctatggtatcacctgggtgcgacaggGCcccctggacacggccttgagtggatggggtggatcagcgttcacgatggcaacacaaactatgcacagagtctccagggcagagtcaccctgaccacagacacatctacgagcacagcctacatggaactgaggggtctcagatctgacgacacggccgtttattattgtgcgagagatcgcccgaatgaattctggggccagggaaccctggtcaccgtcttctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21551 JY8QFUQ01BWTX8 unproductive (see comment) Homsap IGHV3-48*02 F 986 94.95 207/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 3 8 8 X 8.8.X [1.17.38.11] CARPAGAG*PFFA#YYSGLDVW out-of-frame + stop codons cctctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtggatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggcagggtgacccttttttgccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21552 JY8QFUQ01BJZUF productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 869 88.99 194/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARVRGYYGGQYFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21553 JY8QFUQ01AEL2L unproductive (see comment) Homsap IGHV4-30-2*02 F, or Homsap IGHV4-55*06 P or Homsap IGHV4-59*01 F or Homsap IGHV4-59*02 F or Homsap IGHV4-59*03 F or Homsap IGHV4-59*07 F or Homsap IGHV4-59*09 F or Homsap IGHV4-61*01 F or Homsap IGHV4-61*03 F or Homsap IGHV4-61*07 F or Homsap IGHV4-61*08 F 189 91.3 42/46 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD1-26*01 F 2 X X X X.X.X [X.X.15.11] CARGGSVGATGI*SRD## out-of-frame - stop codons gatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtcggtgggagctactggaatctgatcccgggactgggggccagggaaccctggtcaccgtctactccagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21554 JY8QFUQ01BEG02 unproductive (see comment) Homsap IGHV3-48*02 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [2.17.38.11] CARAGGWEI##YFDYW out-of-frame + stop codons acctctggattcatcttcagtcagtataaaatgaattgggtccgccaggctccagggaaggggctggagtgggtttcagaaattagttttagaagcagaaccgtacactacgcagactctgtgaggggccgcttcaccgtctccagagacaatgccaagaactcactgtatctacaattgaacagcctgagagacgaggacacggctatatattactgtgcgagagcggggggctgggagattcgactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21555 JY8QFUQ01CC6FI productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.64 195/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21556 JY8QFUQ01BZ6X5 No results 21557 JY8QFUQ01CKAZJ productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F or Homsap IGHV3-69-1*01 P 814 86.57 187/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 7 12 8.7.12 [2.17.38.11] CAGSGRDPYGINVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) gcctctggattcaccgtcagagataactacgtgacctgggtccgccaggctccagggaaggggctggaatgggtctcaattatttatatcagtggtagcacatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttctt 21558 JY8QFUQ01BPEGS productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 21559 JY8QFUQ01CN2FZ productive (see comment) Homsap IGHV3-48*01 F 1080 99.54 216/217 nt 99.08 215/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 18 8.8.18 [1.17.38.11] CASIFGVVPLGNYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagGaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgatttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21560 JY8QFUQ01DGF6D productive (see comment) Homsap IGHV1-8*01 F 960 95.26 201/211 nt 94.79 200/211 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [X.16.38.11] CARGDSSAYPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 53 of V-REGION: 1 nucleotides (from position 68 in the user submitted sequence), (cause frameshift) gatacaccttcatcaattatgatatccactgggtgcgacaggccactggacaagggcttgagtggatggacggatgaacccgaacagtggtaacacaggctatgcaccgaagttccagggcagagtcaccatgaccagggacacctccataagcacagcctacatagagttgaccagcctgagatctgaggacacggccgtgtattactgtgcgagaggggacagtagcgcttaccccgactattggggccagggaaccctggtcaccgtctcctcaccatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21561 JY8QFUQ01CMHIL productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 231 97.92 47/48 nt Homsap IGHD6-25*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARHEGYNSRYYYFGYW in-frame + gttctggatacagctttgccaccttctggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggaatgatctttcctggtgactccgataccagatacagcccgtccttccaaggccaggtcaccttctcagccgacaagtccatcaacaccgcctacctgcagttgaacagcctgacggcctcagacaccgccgtttattactgtgcgagacatgaaggatataacagccgttactactactttggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21562 JY8QFUQ01A7LQC productive Homsap IGHV4-59*02 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 3 8 7 17 8.7.17 [1.17.38.11] CARHSMGVTIVRGHWFDPW in-frame + tctctggtggctccgtcagcagttattactggagctggatccgacagcccccagggaagggactggagtggattggctatatccatgacagtgggagcagcaactacaacccctccctcaagagtcgagtcaccatatctgtggacacgtccaagaaccagttctccctgaagctgacttctgtgaccgctgcggacacggccgtatattactgtgcgagacattctatgggtgttactatagttcggggacactggttcgacccctggggccagggaaccctggtcaccgtctcatcagcctccaccaagggcccatcggtcttcccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaacctc 21563 JY8QFUQ01B3HUT productive Homsap IGHV4-39*02 F 947 91.86 203/221 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD1-26*01 F 3 10 7 13 10.7.13 [1.17.38.11] CARRYSWNYERFDPW in-frame + tctctggtgactccatcagtactaataattactactgggcctggatccgccagcccccagggagggggctggagtggattgggaatatctattatagcgggaccacctactacaatccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccacttctccctgaggttgagttctgtgaccgccgcagacacggctctctattactgcgcgcggcgatatagttggaactacgaaaggttcgacccctggggccagggaaccctggtcatcgtctcctcagcctccaccaagggcccatcgtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21564 JY8QFUQ01APBO9 No results 21565 JY8QFUQ01DFUY0 unproductive (see comment) Homsap IGHV5-51*04 F 869 88.99 194/218 nt 87.16 190/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CACYFDSKWF#FDYW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'TA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'TC' (2 nucleotides at position 125 to 126 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); gttctggatacgtctttccctcctactggatcgcctgggtgcgccagatgccccggTAaaaggcctggagtggctgggaaccatctatcCccggcgactctgacaccacatacagcccgtcattTCccaaggccaggtcaccatgtcagtcgacacgTcccgtcagcaccgcctacttgcagtggagcagcctgaaggcctcggacagcgccatttactattgtgcgtgttattttgatagtaagtggtttctttgactactggggccagggaacccaggtcaccgtctcctccagcctccaccaagggccatcggtcttgccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21566 JY8QFUQ01AI0WO No results 21567 JY8QFUQ01DGWWO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-22*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKENYFESSGYHGMNVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) or Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactatgccatgacctgggtccgccaggctccagggaaggggctggaatgggtctcaactattagtaatcgtggtactggagtgtactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagagccgaggacacggccctttattactgtgcgaaagagaattactttgagagtagtggttatcacggtatgaacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagataggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21568 JY8QFUQ01BDY1S No results 21569 JY8QFUQ01B2PSJ unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21570 JY8QFUQ01CUSAF unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*04 F 786 85.51 183/214 nt 84.58 181/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGFYGDYFDSW in-frame + stop codons in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'GC' (2 nucleotides at position 46 to 47 in the user submitted sequence), (cause frameshift); tggatacaccttcaccggActacttcatacactggctgcgcaaggGCcccctggataacgacttgagtggatgggatggatcaaccctaagaatggtgacacaaagtatgcacagaactttcagggccgggtcaccatgaccagggacacgtccgtcagcaccatatatgtggaggtgagcagcctggaatctgacgacgcagccacttattactgtgcgagaggcttttatggtgactactttgactcctggggccagggagccgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21571 JY8QFUQ01APX1Q No results 21572 JY8QFUQ01AFCMU unproductive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 941 92.66 202/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYD*GEYAMDVW in-frame + stop codons gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactagggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21573 JY8QFUQ01A3GYC unproductive Homsap IGHV1-2*02 F 826 87.79 187/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [0.16.38.11] CARDGISMTLVRGVRPFDY## out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) tggatacaccttcatcggccattatatacattgggtgcgacaggccctggacaagggcttgaatgggtggggtggatcaaccctaacagtggtgttacaaactatgcacagcagtttcaggacagggtcaccatgaccgtcgacacgtccatcagcactgcctacatggacctcaaaagtctaaagtctgacgacacggccatctattactgtgcgagagacggaataagtatgactctggttcggggagttaggcccttcgactactgggggccagggaaccctggtcagcgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21574 JY8QFUQ01DH0U6 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 962 92.41 207/224 nt 91.52 205/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggGggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaAaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21575 JY8QFUQ01ABZJI unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDAKSGDA#EAFDIW out-of-frame + stop codons in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggGAagggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatgcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21576 JY8QFUQ01CC7HQ productive (see comment) Homsap IGHV4-61*02 F 878 89.04 195/219 nt 88.13 193/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 10 7 13 10.7.13 [1.16.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ctccggtggctccatcagtactggttattactactggGagctggatccggcagtccnccgggaagggactgaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21577 JY8QFUQ01C8FZV unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 887 89.91 196/218 nt Homsap IGHJ4*02 F (see comment) 69 60.42 29/48 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [1.17.38.11] CAAQIWGHGELFSKYW# out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctcttttaccgccgcagacacggccgtgtattactgtgcggcccaaatctggggtcatggggagttattttccaaatattgggggcccgggaatcctgggtcaacgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagccctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21578 JY8QFUQ01A4T7B unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null + No rearrangement found ctgagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 21579 JY8QFUQ01AAX25 productive Homsap IGHV3-30*02 F, or Homsap IGHV3-30-5*02 F 1049 98.17 214/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-13*01 F 3 8 8 12 8.8.12 [1.17.38.11] CVKVGQLGDGMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaccttcagtagctatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcatttatacggtatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacactctgtatcttcaaatgagcagtctgagagctgaggacacggctgtgtattactgtgtgaaagtgggtcagctgggggacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagggagtgcatccgccccaaccct 21580 JY8QFUQ01CPCJB productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 987 94.55 208/220 nt 94.09 207/220 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [2.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'T' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); ggcctctggattcactttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatTgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaacccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21581 JY8QFUQ01B2X5Y productive Homsap IGHV3-9*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDGSAIPVTGTYFEYW in-frame + cctctggattcacctttcatgattataccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtattagttggaatagtggtaacatagactatgcggcctctgtgaggggccgattcaccgtctccagagacaacgccaataactccctgtctcttcagatgaatggtctgagatctgaggacacggccctctattactgtgcaaaagacgggtcggcgataccagtgactggtacctactttgaatactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 21582 JY8QFUQ01AOB3M unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CANELGYCSGG## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacctttagtagtcatgtcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattcgtgccagtaatgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacactgtatttacaaatgtacagcctgagagtcgaggacacggccgtatattactgtgcgaacgaactcggatactgtagtggtgggggggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21583 JY8QFUQ01BV15J productive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-6*01 F 1 9 7 16 9.7.16 [1.17.38.11] CARDQRGRFGTSSTFDYW in-frame + tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgtgcgagagatcagcggggccgatttggcacctcgtcaacctttgactactggggccagggagcccaggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggcaacgtggtcgtcgcatgcctggtccagggcttcttccccc 21584 JY8QFUQ01AK0SS productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*06 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 8 13 8.8.13 [0.17.38.11] CARGDGYNFGGLDYW in-frame - tggattcaacttcataggttatggcatgcactgggtccgccaggctccaggcaaggggctagagtgggtggcagttatatcgtatgatggcaagaacatcttttatgcagactccgtgaggggccgatccatcatttccagagacgattctaagagaacactgtttctgcaaatggacagcctgagagctgaggacacggctgtctattattgtgcgaggggagatggctacaatttcgggggattagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21585 JY8QFUQ01C3XGP productive (see comment) Homsap IGHV2-5*02 F (see comment) 882 84.84 207/244 nt 84.43 206/244 nt Homsap IGHJ4*01 F 195 89.58 43/48 nt Homsap IGHD1-1*01 F 2 10 7 11 10.7.11 [9.17.38.11] CARIGRLEHFDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (84,84% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); gactctcacgctgacctgtaccgtctctggcttctcgctctccactcctggcgtgggcgtggcctggctccgtcagTcccccaggagaggccctggagtggcttgcactcatttactgggatgatgatagccgctatagcccatctctgaaggacagactcaccatcaccaaggacacctccgaaaaccttgtggtcctgacactcagcgacatcgatacagtggacatcgccacatatttttgtgcacgcataggccgtctggaacactttgactcctggggccaaggaatactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21586 JY8QFUQ01CZE4X productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21587 JY8QFUQ01A841E unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 877 89.81 194/216 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKEQRGSGWSRSALDV# out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) tctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctgggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21588 JY8QFUQ01B5WL6 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1017 96.77 210/217 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD2-21*02 F 3 8 8 20 8.8.20 [1.17.38.11] CARLPYIVVLTNIISPTYFDFW in-frame + ttctggatacagttttaccagttactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatgggtatcatctatcctgctgactctgataccagatacagcccgtccttccaaggccaggtcagcatctcagccgacaagtccatcgacaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccatgtattactgtgcgcggctgccatatattgtggtgctgactaatataatctccccaacctactttgacttctggggccagggaaccccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21589 JY8QFUQ01AN5AH productive Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1073 98.64 218/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-6*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARDRGPSSSSKMEYDYW in-frame + tctctggtggctccatcaacagtggtggttactactggagttggatccgccagcacccagggaagggcctggagtggattgggtacatctattacagtgggagtacctactacaacccgtccctcaagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgactgccgcggacacggccgtgtattactgtgcgagagatcggggccctagcagctcgtccaaaatggaatatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccatggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21590 JY8QFUQ01CTCEY productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); tggatacacCcttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaaccgtggtcgtcgcatgcctggtccagggcttcttccc 21591 JY8QFUQ01BD4OW unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 777 83.41 186/223 nt 82.51 184/223 nt 8 10 X 8.10.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (83,41% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 83 of V-REGION: 'G' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 180 to 180 in the user submitted sequence), (cause frameshift); ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcGaaaaaacatggtgtatctgAcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgtagggactcggggtccaccgtctcctcagcatccccgaccagccccaaggtccttcccgctgagcctctgccagcacccagccagatgggaacgtggctcatcgcctgcctggtccaggggcttcttccccccaggagcc 21592 JY8QFUQ01CZCQ1 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggatcacctttggttattgatggcatgagctgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21593 JY8QFUQ01C1VSK productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*05 F (see comment) 767 83.26 184/221 nt 82.35 182/221 nt Homsap IGHJ4*02 F (see comment) 141 77.08 37/48 nt Homsap IGHD3-3*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRWSGTYPFASW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'T' (1 nucleotides at position 211 to 211 in the user submitted sequence), (cause frameshift); tctctggtggctcactcagaagtagtagtcaccattggggctggattcgtcagTccccccgggaaggggctggagtggcttgggactgtcgactttcgtgggaccacccactacaacccgtccctcatgggtcgactcacgatatccgtcgacgcgcccaagagtcaaatgtccctgcacttgagctctgtgaccgccgcagacacggctTttttacttctgtgcgagacgctggagtgggacttatccgtttgcctcctggggccagggcatcccggtcatcgtctccccagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21594 JY8QFUQ01CJEC0 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 876 94.36 184/195 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccg 21595 JY8QFUQ01DGMMR No results 21596 JY8QFUQ01B53Q6 productive Homsap IGHV1-3*01 F 966 94.86 203/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + tggatacaccttcagtacctatactatgaattgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21597 JY8QFUQ01BKCCN unproductive Homsap IGHV3-48*01 F 873 89.4 194/217 nt 86.64 188/217 nt Homsap IGHJ4*03 F (see comment) 132 75.0 36/48 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [1.17.38.11] CARASTFYYDGSGYRDVFDI## out-of-frame - Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 43 of V-REGION: 'T' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 91 in the user submitted sequence), (cause frameshift) tctctggcttcagtttgagtacctTataccatgGaactgggtccgTccaggctccagggaaggggctggagtgggtttcactcattagtaagatagtaatgtcatatactacgcGggactctgtgaAagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatgggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacccctcctccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcag 21598 JY8QFUQ01CSJ0C productive Homsap IGHV3-7*03 F 842 87.61 191/218 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21599 JY8QFUQ01CW0P2 unproductive Homsap IGHV3-7*01 F 891 90.32 196/217 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [1.17.38.11] CVRDGGVIVVVPMDYYGMDV## out-of-frame + ctctggtttcacatttagtacgtactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcgagatggaactgagagtcattatgtggactctgtgaagggccgattcatcatctccagagacaactccaggaatttactgtatctccaaatgaacagcctgagagtcgaagacacggctgtgtattattgtgtgagagatgggggtgttattgtagtagtgccaatggactattacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21600 JY8QFUQ01ARQ2P productive (see comment) Homsap IGHV3-7*01 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.16.38.11] CAISSDFYSTGHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 37 in the user submitted sequence), (cause frameshift) ctctggattcaacttcagaacctattggatgggctggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21601 JY8QFUQ01AIBXR No results 21602 JY8QFUQ01BCNOO unknown (see comment) Homsap IGHV3-48*03 F 883 89.5 196/219 nt 89.04 195/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggAttttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21603 JY8QFUQ01CD118 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 801 85.71 186/217 nt 85.25 185/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-16*02 F 2 8 8 17 8.8.17 [1.17.38.11] CVKDRDFLWGTYRLQLEHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcagatttagcagctatgccatgagctGgggtccgccagactccagaaaaggggcttgaatgggtctcaggcatcaatgataacggtcgaagcataaactacgcgggctccgtgaagggccggttcaccatctccagagacaattccaagagcacgttgtatctgcagatggatagcctgagccccgaggactcgggcatatattattgtgtgaaagatcgtgatttcctttggggcacttatcgtcttcaacttgaacattggggccagggagccctggtcagcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 21604 JY8QFUQ01AJ5UO unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaacctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21605 JY8QFUQ01BXKPL productive (see comment) Homsap IGHV3-74*03 F 837 87.56 190/217 nt 86.18 187/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctggattcacgtttCcacacctcctggatgcactgggtccgccaaggtccaggGgagggggctaatgtgggtctcacgaatcaatactgatgggagtaacacaatgtacgcggactccgtaaAagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21606 JY8QFUQ01CKWEZ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 944 93.49 201/215 nt 93.02 200/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 65 of V-REGION: 2 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) ctctggattcacctttggttattatggcatgagctgggtccgccaagctccggggagggggctggagtgggtctctggtattaatcggaatggtgatagcaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21607 JY8QFUQ01CMIT0 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 91.78 201/219 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKKYHYGSGTYLYYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactgggggccagggaaccctggtcaccgtctcctcagcattcccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21608 JY8QFUQ01CJVQ5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 952 92.34 205/222 nt 91.89 204/222 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD4-11*01 ORF 3 8 8 16 8.8.16 [3.17.38.11] CAKQTNFSTTTTTVWTSG in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 and Homsap_IGHJ5*01 and Homsap_IGHJ6*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 28 of V-REGION: 'A' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift); gcagcctctggaAttcatgtttagtagctttcccatggcctgggtccgccaggctccagggaaggggctggagtgggtctctagtattagtggtaggggtggtaacacatacttcgcagactccgtgaagggccggttcaacatctccagagacaattccaagaacacgatgtatttgcaaatgaacagcctgagagccgaggacacggccttatattactgtgcgaagcagacgaatttttcgactactactactacggtttggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21609 JY8QFUQ01AJLXW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-21*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtttattactgtgcgagaggccgaatagtgtcggttggtatgtcaggctggttcgacccctggggccagggaaccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21610 JY8QFUQ01DPD05 No results 21611 JY8QFUQ01DAAJK productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 16 10.7.16 [1.17.38.11] CARGPKYYYDSSGFEDLW in-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaggtcccaagtattactatgatagcagtggtttcgaagacctctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21612 JY8QFUQ01AWYBC productive (see comment) Homsap IGHV3-7*01 F 903 91.16 196/215 nt 90.23 194/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 7 8 14 7.8.14 [1.16.38.11] CARGSYWHYDTFGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 28 of V-REGION: 2 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 76 in the user submitted sequence), (cause frameshift) cctctggattacttttacaactattggatgacctgggttcgccaggntccagggaaggggctggaatgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21613 JY8QFUQ01APB9W No results 21614 JY8QFUQ01CKBE4 No results 21615 JY8QFUQ01CCNXT productive Homsap IGHV3-7*01 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [0.17.38.11] CARGSYWHYDTFGDYW in-frame - ctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21616 JY8QFUQ01BX80Q productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame - gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21617 JY8QFUQ01DLL7L productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 799 85.98 184/214 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-6*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARDSSNWSDAFDIW in-frame - ntctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcttttgatatctggagccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21618 JY8QFUQ01AVLQ7 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-2*01 F 1 8 8 19 8.8.19 [1.17.38.11] CTKDYPDGRLLNQVRPFFDDW in-frame - cctctggattcacctttagcgactatggcatgagttgggtccgccaggctccagggaagggactggagtgggtctcaagtattatcgctaatggtggtgacacacactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagatgaacagccttagaggcgaggacacggccgtatattattgtacgaaagactatccggacggccgcttgttgaatcaggtgcgccccttctttgacgactgggaccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21619 JY8QFUQ01BW8TM unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 229 57.36 113/197 nt 8 8 X 8.8.X [1.17.31.X] null - No rearrangement found Low V-REGION identity (57,36% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21620 JY8QFUQ01CQPW7 No results 21621 JY8QFUQ01CCIFC unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); ctctggattcacctttatcaactatggcatgagctGgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21622 JY8QFUQ01B126V unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CANEFGYCSGRG# out-of-frame - in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggtttcacctttagtagtcatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaactattcgagccagtggcgataggacacactacgcagactccgtgAaagggccgcttcaccatctccagagacaactccaagaacacgctgtatttgcaaatgtacggcctgagagtcgaggacacggccgtatattattgtgcgaacgaattcggatactgtagtggtcgggggggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21623 JY8QFUQ01AZH1L productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21624 JY8QFUQ01B6TCJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21625 JY8QFUQ01CGYCC unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21626 JY8QFUQ01AN6GB No results 21627 JY8QFUQ01BZ48Y productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 972 94.47 205/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDLFQVSTTYFDYWG in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggccgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactgggggcccgggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21628 JY8QFUQ01BWN32 productive (see comment) Homsap IGHV3-9*01 F 968 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CAKDAMGGAGDWAAFGIW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 98 of V-REGION: 'A' (1 nucleotides at position 198 to 198 in the user submitted sequence), (cause frameshift); cctctggcttcatctttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaggtattagttggaatagcgctaccatagaatatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctggaaatcaacagtctgagacctgaaAgacacggccttatactactgcgcaaaagatgcgatgggaggagctggtgattgggctgcttttggtatctggggccaggggacaatggtcactgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21629 JY8QFUQ01CLLPW productive (see comment) Homsap IGHV3-30*01 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD2-15*01 F 3 8 8 16 8.8.16 [2.17.38.11] CAKDELPWDTIEYYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); aggcctctggattcaccttcaatacctattcGtatgcactgggtccgccaggctccaggcaaggggctagagtgggtgtcagttatttcatatgatggaagtaagaaatactacgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatgaacagcctgagacctgaggacacggctgtttattactgtgcgaaagatgagctgccttgggataccatagagtactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21630 JY8QFUQ01C8HCR unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 412 81.97 100/122 nt 8 8 X 8.8.X [1.17.6.X] null + No rearrangement found Low V-REGION identity (81,97% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta 21631 JY8QFUQ01B84CX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 927 92.17 200/217 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD7-27*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDQSLGMPEAFDIW in-frame - ctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctggggatgcccgaggcttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21632 JY8QFUQ01C87ZL unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null + No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21633 JY8QFUQ01AXHEJ productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21634 JY8QFUQ01CYK0K productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-18*01 F 3 8 8 21 8.8.21 [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataGggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21635 JY8QFUQ01BAZB8 No results 21636 JY8QFUQ01CVQCY No results 21637 JY8QFUQ01DKYS7 unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + cctctggattcacatttagtaattattggatgatctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggtttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21638 JY8QFUQ01AXBNA unproductive (see comment) Homsap IGHV3-7*01 F 970 93.24 207/222 nt 92.79 206/222 nt Homsap IGHJ4*03 F (see comment) 78 62.5 30/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [3.17.38.11] CAKGGW*##DLDYW out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'CAA' (3 nucleotides at position 16 to 18 in the user submitted sequence), (do not cause frameshift); gcgacctctggagttCAAccctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaagcccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21639 JY8QFUQ01AATBN unproductive Homsap IGHV3-7*01 F 928 91.78 201/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.16.38.11] CVRDRLYDSSGYDFGGIGGTI#DHW out-of-frame - in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) agcctctggattcatgtttagtgactattggatgagctgggtccgccaggctccagggaagaggctgagtgggtggccaacataaggaaagatggaagtgaggcgtactatgtggaatctgtgaagggccgattcaccatctccagagacaacgccaggaactcactgtttctgcagatgaacagcctgagggccgaagacacggctgtatatttctgtgtgagagatcgtctctatgatagtagtggttatgactttgggggaattggggggactattcagaccactggggccagggaacccaggtcaccgtctccacagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21640 JY8QFUQ01C0I7Y productive Homsap IGHV1-24*01 F 970 95.31 203/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame + cggaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21641 JY8QFUQ01AGS4P productive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*11 F 850 88.43 191/216 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcaccttcagtacctatgctatgtactggatccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21642 JY8QFUQ01B8CUG productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 885 90.65 194/214 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD4-17*01 F 2 8 8 20 8.8.20 [0.17.38.11] CTRTQFDPDYGDYETGYGMDVW in-frame - tggattcaacttccgatcttatgccatgtactgggtccgccaggccccaggcaaggggctggactgggtggcagttatttggcatgatggcagtaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacattgtttctgcaaatgaacagcctgagagtcgaggacacggctgtctattactgtacgaggacgcaatttgaccctgactacggtgactacgagacggggtacggtatggacgtctggggccaagggacaacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21643 JY8QFUQ01B2K4L No results 21644 JY8QFUQ01C12M6 No results 21645 JY8QFUQ01AO83E No results 21646 JY8QFUQ01AFQ6R productive (see comment) Homsap IGHV4-4*07 F 871 90.14 192/213 nt 88.73 189/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 6 13 8.6.13 [1.17.37.11] CARDFGGSYNLVAYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'CTCACTG' (7 nucleotides at position 28 to 34 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 108 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattCTCACTGactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21647 JY8QFUQ01CT1FJ productive (see comment) Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt 83.49 182/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 3 8 8 16 8.8.16 [2.17.37.11] CVKDMVAGQGLLSRFDHW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 70 to 70 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 113 in the user submitted sequence), (cause frameshift) gcctctggattcgactttaaggaatatgccatacactgggtccggcaagttccaggaaagggcctggagGtgggtcgcgggcaGtcaactggaatcggggcaaagcattgtatgggactctgtgaggggccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaagacatggtcgcgggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21648 JY8QFUQ01BLI62 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 835 88.26 188/213 nt 87.32 186/213 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [1.17.37.11] CARKGLVPSMFFFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 97 of V-REGION: 1 nucleotides (from position 192 in the user submitted sequence), (cause frameshift) ctctggtgggtccttcagtggttacttctGggaactggatccgccagcccccagggaaggggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccgggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21649 JY8QFUQ01BHCZE productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 788 84.86 185/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-10*02 F 2 8 8 13 8.8.13 [1.17.38.11] CAKERDNNVLPVDSW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcagcttcaatagttatactttgagttgggtccgccaggctccagggaaggggctggagtgggtctcagctatcagtggaacaggtgaaacaaccttctacgcggactccgtgaggggccggttcaccgtctccagagacaatttcaagaatactctgtacttgcaattgagcgacctgagagccgaagacacggccgtctattactgtgcgaaggagagagataacaatgttctgcccgttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21650 JY8QFUQ01ANOBY No results 21651 JY8QFUQ01C14UQ unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1060 100.0 213/213 nt Homsap IGHJ4*02 F 82 62.5 30/48 nt Homsap IGHD3-16*01 F 3 8 7 X 8.7.X [1.17.38.11] CASANYDYVLGGVIL*LL## out-of-frame - stop codons tctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcctcagccaattatgattacgttttggggggagttatcttatgactactgggggccaggggaacccctggtcaccntctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21652 JY8QFUQ01BMBTD productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - ctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21653 JY8QFUQ01BXELX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccGagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21654 JY8QFUQ01CPP66 unproductive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 993 94.17 210/223 nt Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD4-11*01 ORF 2 8 10 X 8.10.X [1.17.38.11] CVRHEGTPVSDVGGYGMDV# out-of-frame + ctctggtttcacgttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagtaaagcttacagttccacgacagcatatgctgcgtcggtgaaaggcaggttcaccatttccagagatgattcaaagaacacggcgtatctgcacatgaacagtgtgataaccgaagacacggccgtgtattattgtgttagacatgaagggactcccgtaagtgatgtaggaggatacggcatggacgtctggggccagggtccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21655 JY8QFUQ01CE4CX productive (see comment) Homsap IGHV3-11*01 F 844 86.94 193/222 nt 86.49 192/222 nt Homsap IGHJ6*02 F 263 94.83 55/58 nt Homsap IGHD1-26*01 F 3 8 8 11 8.8.11 [3.17.38.11] CVRDYYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'GGG' (3 nucleotides at position 100 to 102 in the user submitted sequence), (do not cause frameshift); cagcttctggggttctccttcagcgactacttcatgagttgggtccgccaggctccagggaagggactggagtgggttgcatacattagtagtagtggtGGGactactaaatactacgcagactctgtgaagggccgattcaccatctccagggacaacggcaagaattcattgtttctgcaaatggacagcctgagagtcgacgacacggccatgtatttctgtgtgagagactactattattacgggatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21656 JY8QFUQ01BENBF No results 21657 JY8QFUQ01C270Z productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 903 91.59 196/214 nt Homsap IGHJ1*01 F (see comment) 170 80.77 42/52 nt Homsap IGHD2-21*02 F 2 8 8 13 8.8.13 [0.17.38.11] CATIPSYCGGDCYYW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtatactactgtgcgaccatcccttcgtattgtggtggtgactgctattactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21658 JY8QFUQ01BNI7F No results 21659 JY8QFUQ01AH4OV productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcctatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgt 21660 JY8QFUQ01BJUZZ unproductive (see comment) Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-16*02 F 1 8 8 X 8.8.X [1.17.38.11] CAKGGGKRRP*LL# out-of-frame + stop codons ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgaccagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttc 21661 JY8QFUQ01AKF0A productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + cctccggattcacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaatgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21662 JY8QFUQ01B20M9 productive (see comment) Homsap IGHV3-74*03 F 851 88.07 192/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRDSDSSASYFAHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 103 to 103 in the user submitted sequence), (cause frameshift); cctctggattcactttccacacctcctggatgGcactgggtccgccaaggtccaGGgggagggggctaatgtgggtctcacgaatcaatactgatgggagtaAacacaatgtacgcggactccgtaaagggccggttcaccatttccagagacaatgccaagaatacggtgtttctgcaaatgaacagtctgaaagccgacgacacggctgtctattattgtgttagagattcagacagtagcgcctcgtacttcgcccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21663 JY8QFUQ01BF9DY productive Homsap IGHV3-11*04 F (see comment) 940 93.06 201/216 nt Homsap IGHJ6*02 F (see comment) 220 83.87 52/62 nt Homsap IGHD2-2*01 F 2 8 7 22 8.7.22 [2.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01BF9DY ; 8 AA in Homsap_IGHV3-11*04) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (shorter alignment but highest percentage of identity) gcctctggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacaacggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21664 JY8QFUQ01C2RTA unproductive Homsap IGHV4-61*02 F 875 88.69 196/221 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [1.17.38.11] CARQGDSSGPWNDY## out-of-frame + tctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggattggaatggattgggcgcatgtctgccagaggggacagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttttccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtg 21665 JY8QFUQ01B9OP9 unproductive (see comment) Homsap IGHV3-30*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [1.17.38.11] CVKK*PVLGHNR##YFDYW out-of-frame + stop codons ctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 21666 JY8QFUQ01AU5EY unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 943 91.48 204/223 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD3-3*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTDRRGSDIPPQFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggatttagtttcaanaacgcctggatgagctgggtccgccaggctccagggaaggggctggagtgggttggccgtattaaaagcaaagctgatggtggggcggcagactacggtgcacccgtgagaggcagattcaccatctcaagagatgattcaagaggcacggtgtctctgcaaatgagcagcctgaaaaccgaggacacagccatctattattgtaccacagataggaggggttcggatattccacctcaatttgactactgggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21667 JY8QFUQ01BPRNF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 943 93.9 200/213 nt 92.96 198/213 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 7 7 11 7.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 16 in the user submitted sequence), (cause frameshift)in CDR2-IMGT, from codon 56 of V-REGION: 3 nucleotides (from position 81 in the user submitted sequence), (do not cause frameshift) ctctggattcaccttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21668 JY8QFUQ01BQM9S unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21669 JY8QFUQ01CI0N7 No results 21670 JY8QFUQ01ANAH2 productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21671 JY8QFUQ01BB70S productive Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 939 93.46 200/214 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD3-16*02 F 3 8 8 11 8.8.11 [0.17.38.11] CARGDLPHYIDYW in-frame - tggatacatcttcaccagctactttatgcactgggtgcgacaggcccctggacaagggcttgagtggatgggaatagtcaaccctagtggagctggcacaacttacgcacagaagttccagggcagagtcaccatgaccagcgacacgtccacgaccacagtctacatggagctgagcagcctgagatccgacgacacggccatatattactgtgcgagaggcgatctcccccactacattgactactggggccagggaaccctggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21672 JY8QFUQ01CFZB2 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 624 93.62 132/141 nt 8 8 X 8.8.X [1.17.12.X] null + No rearrangement found ctctggattcactttcagtaactactggatgtactgggtccgccaagctccagggaaggggctggagtgggtctcacgtattaatggtgatggaagtagtacaagttacgtggactccgtgaagggccgattcaccatctc 21673 JY8QFUQ01CCNVJ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1080 100.0 217/217 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD2-2*01 F 3 8 8 18 8.8.18 [1.17.38.11] CAKFMGVVVVPAAHNWFDPW in-frame + ctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaattcatgggagttgtagtagtaccagctgcccacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21674 JY8QFUQ01CC56Z No results 21675 JY8QFUQ01B8HFY unproductive Homsap IGHV3-7*01 F 999 95.85 208/217 nt 94.47 205/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 7 8 X 7.8.X [2.16.38.11] CAISSGYYSTGY## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 28 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 70 in the user submitted sequence), (cause frameshift) ggctctggatcagctttagttactattggatgagctgggtccgccaggctccagggaaTggggctggagtggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21676 JY8QFUQ01A5HTL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 677 78.73 174/221 nt 78.28 173/221 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found stop codons Low V-REGION identity (78,73% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cagcctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaAaggggctggagtgggtctcagctattagtggtagtggtggtagcacatactacgcagactccgtgaagggccggttcaccatctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgcaacccggtgacggtgtcgtggaactcag 21677 JY8QFUQ01CPH1K productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD1-26*01 F 1 8 8 9 8.8.9 [1.17.38.11] CTREVGATDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggGggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagaggtgggagctaccgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21678 JY8QFUQ01A87UU productive Homsap IGHV3-48*01 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARERGNSYGEIDYW in-frame - tctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21679 JY8QFUQ01BZCPP unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKGF# out-of-frame + cctcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21680 JY8QFUQ01CFWNI unknown (see comment) Homsap IGHV3-30*10 F 92 51.8 72/139 nt 8 8 X 8.8.X [1.17.12.X] null + No rearrangement found tctggattctccttcagaagttactctttccactgggtccgccaggctccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21681 JY8QFUQ01B64QD productive (see comment) Homsap IGHV4-34*03 F 885 90.61 193/213 nt 90.14 192/213 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.16.38.11] CVRNYYDFSGYFNWFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 50 in the user submitted sequence), (cause frameshift) tgtctggtgggtccttcagtggttactactggagttggatccgccagccccagggaaggggctggagtggattggggaaatcaattatagaggaagtaccaactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21682 JY8QFUQ01CR8IV productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 893 89.59 198/221 nt Homsap IGHJ3*01 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 10 7 16 10.7.16 [1.17.38.11] CTNDFSMAVRATHAFHVW in-frame + tctctggtgactccattggtagtagtgcttactactggggctgggtccgccagcccccagggaaggggctcgaatggatagggaatatttactatggtggcagcacctactacaacccgtccctcaagaatcgagtcaccatatcggtagacacgtccaagaaccagctcttcctggagctgacctctgtgaccgccgcagacacggctctttattactgtacgaacgacttttcaatggcggtacgtgctacgcatgctttccatgtctggggccaagggacaatggtcgccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21683 JY8QFUQ01ADRQ3 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 97.69 211/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [2.17.38.11] CARLGARFGD#DYW out-of-frame - stop codons in FR2-IMGT at codon 39 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 79 to 79 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctacCtggagctggatccggcagcccccagggaagggactggagtggattggGgtatatctattacagtgggagcaccaactacaaccCcctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21684 JY8QFUQ01AV6LD productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 839 86.88 192/221 nt 86.43 191/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-17*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARRHYGEGLFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); cctttggtggctccatcaccaataataattacttctggggctggatccgccagcccccagggaaggggctggagtggattgggggAtgtccagtatagtgggagcacctactccagcccgtccctcaagaggcgggtcaccatgtctgtggacgtgtccaaaagtcaggtctccctgagactgagctctgtgaccgccacagacacggctatttattactgtgcgagacgtcattacggtgaaggcttgtttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21685 JY8QFUQ01B6LOD No results 21686 JY8QFUQ01CPEX7 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F or Homsap IGHV4-55*03 P 815 86.24 188/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-22*01 F 2 9 7 15 9.7.15 [1.17.38.11] CTSREHAFSGQFTGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TCA' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'T' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); tgtctggtgtctccgtcaccagcgTCAgtcactggtggacctgggtccgccagcccccagggaagggactggagtggattggagaaatctattTattatggcatcaccaatttcaacccgtccctcaagagtcgaatcagcatgtcagtggacgagtccaagaaccagttctccctgagactgacttctgttaccgccgcggacacggccgtttattattgtacgagtcgcgaacatgcttttagtggtcaattcacgggtgactactggggccagggaaccctgatgaccgtcacctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21687 JY8QFUQ01CT2M9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 91.74 200/218 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKKYHYGSGTYLYYFDYW in-frame + cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgaccagcctgagagccgaggacacggccgtatatttctgcgcgaagaagtatcactatggttcggggacttacttgtactattttgactactggggccagggaacccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21688 JY8QFUQ01AARZS unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-6*01 F 2 9 7 X 9.7.X [1.17.38.11] CARDQRGRFGTSSTFDY## out-of-frame - tctctggtgactccatcagcaatgatagttggtggagttgggtccgccagcccccagggaaggggctggagtggattggggaaatctatcatactgggagcaccaactacaacccgtccctcaagagtcgagtcaccatatcactcgacaagtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacgcggccgtctattactgtgcgagagatcagcggggccgatttggcacctcgtcaacctttgactactgggggccagggagcccaggttaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21689 JY8QFUQ01B81XP productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*03 F 806 85.78 187/218 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD1-1*01 F 3 8 8 10 8.8.10 [1.17.38.11] CVRDLNWSFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttactagttacagtttcaactgggtccgccaggctccagggaaggcgctggagtggatttcatacatcactatcaatggtaatgacaagttctacgcaggctctgtgaagggccgattcgccgtctccagagacgatgccaagaattctctgtatctgcaaatgagcagcctgagagccgaagacacgggtgtttattactgtgtgagggacctcaactggtcttttgactcctggggccagggaaccctggtcaccgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 21690 JY8QFUQ01CLTQ4 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1007 96.74 208/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [1.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 61 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctgagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21691 JY8QFUQ01B9A9Z productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 995 95.41 208/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-15*01 F 3 8 8 17 8.8.17 [1.17.38.11] CARDTLEVVSNMDDAFDFW in-frame + cctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggactactactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgagagatactctagaggtggtgtctaatatggatgatgcttttgatttctggggccaagggacagtggtcaatgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21692 JY8QFUQ01BKTWV productive Homsap IGHV3-9*01 F (see comment) 788 84.86 185/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 8 8 13 8.8.13 [1.17.38.11] CGRIAKPGLGALDLW in-frame + Low V-REGION identity (84,86% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgttggattcacttttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggccgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21693 JY8QFUQ01A7QH2 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [1.17.38.11] CARDFFIGGYYGMDVW in-frame + cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc 21694 JY8QFUQ01B6LAE productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 955 93.15 204/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [2.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) gcctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21695 JY8QFUQ01C0PKL productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARDMGSGRYFEPYDYW in-frame + ggtctggattcatcttcttgaaatatggcatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21696 JY8QFUQ01B43GE unknown (see comment) Homsap IGHV1-18*02 (F) (see comment) 614 78.22 158/202 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [0.17.38.X] null - Rearranged sequence but no junction found Low V-REGION identity (78,22% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. tggttatatctttaccaattatggtgtcagctgggtgcgacaggcccctggacaagggcttgaatggatgggatggataagtaatttcaatggtaacacagactatgcacagaaattccagggcagagtcaccgtgaccacagacacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21697 JY8QFUQ01AFUBY unproductive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGGW*R##LDYW out-of-frame - stop codons cctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21698 JY8QFUQ01AOPB7 No results 21699 JY8QFUQ01B0X5Q unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKSPLSVAGTRQK#WFDPW out-of-frame + gctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaagctggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctcccaagagcacctctgagggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21700 JY8QFUQ01C3QHH productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD2-8*02 F 2 8 8 20 8.8.20 [1.17.38.11] CARDLWLCSGGECYHRGGFENW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift); cctctgggttcaccttcagtaactcctggatgcactGgggtccgccaagctccagggaaggggccggagtgggtctcacgtattaatagtgatgggagtaatacaatctacgcggactccgtgaagggccgactcaccatctccagagacaacgccaaaaaTcacggtgtatctgcaattgaacagtctgagagccgaggacacggctgtgtactactgtgcaagagatctgtggctttgtagtggtggtgaatgctatcatcggggtggttttgagaactggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 21701 JY8QFUQ01ANNUO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + ctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21702 JY8QFUQ01A3HRK No results 21703 JY8QFUQ01AOI6V productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21704 JY8QFUQ01ACIGX No results 21705 JY8QFUQ01B1ER9 unproductive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 1011 97.2 208/214 nt 96.73 207/214 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [0.17.38.11] CARGTAAS##FDYW out-of-frame + stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccagctactatttgcactgggtgcgacaggCcccctggacaagggcttgagtggatgggaataatcgaccctagtggtggtgccacaagctacgcacagcagttccagggcagagtcaccatgaccagggacacgtccacgagcacagtctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcgagggggacagcagcttcgagactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21706 JY8QFUQ01CRCLR unproductive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 877 88.0 198/225 nt 87.56 197/225 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD4-17*01 F 3 8 10 X 8.10.X [2.17.38.11] CTTWFDDFDY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); gcctctggactcactttcagcaacgcctggatgagatGgggcccgccaggctccagggaggggggctgagtgggttggccgcattaaaagtaaagctgatggtgggacaacagactttgatgcagccgtgaaaggcagattcaccctctcaagagacgattcaaaaaatacgatatatctgcaaatgaatcgcctgaagactgaggacacaggtgtttattactgtaccacatggttcgacgactttgactactggggccccgggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21707 JY8QFUQ01BVTDC unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 491 94.5 103/109 nt 93.58 102/109 nt 8 8 X 8.8.X [2.17.1.X] null + No rearrangement found in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaagGgggctggagtgggtctcatacattagtaggagtagtactgacatatact 21708 JY8QFUQ01CEJI6 productive (see comment) Homsap IGHV3-11*01 F 919 93.33 196/210 nt 92.86 195/210 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [X.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 91 in the user submitted sequence), (do not cause frameshift) ggattcagcttcagtgactactacatgagttgggtccgccaggctccagggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactcag 21709 JY8QFUQ01B38K0 No results 21710 JY8QFUQ01AQSQ8 productive Homsap IGHV3-7*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAYFSTGYW in-frame + ctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgcctacttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21711 JY8QFUQ01AUR2T productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 21712 JY8QFUQ01AOLRD productive Homsap IGHV3-7*01 F 909 91.24 198/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 8 8 14 8.8.14 [1.17.38.11] CATSPFTVTTGKDAYW in-frame - ctctagattcacctttaatggttactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21713 JY8QFUQ01DXDOM productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F (see comment) 746 83.26 179/215 nt 82.79 178/215 nt Homsap IGHJ6*02 F 179 77.05 47/61 nt Homsap IGHD2-15*01 F 3 8 7 12 8.7.12 [1.17.38.11] CARDKVISAGRDVW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01DXDOM ; 8 AA in Homsap_IGHV3-21*01), and low V-REGION identity (83,26% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 81 of V-REGION: 'G' (1 nucleotides at position 144 to 144 in the user submitted sequence), (cause frameshift); cctctggattcagtttcactggttttaccgtgatctgggtccgccaggctccaaggaaggggctggaatggatctcatccgtcactactaatggtctcacgtactacgcagactcagtagagggccgattcaacatctccaggGgacaacgccaacaatttagtgtttctgcaaatgaacagcctgagagtcgaggacactggtgtatattattgtgcgagagataaagtgatctctgccggacgggacgtctggggccaagggaccacggtcaccgtctcctcaacatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 21714 JY8QFUQ01AJ1HB productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1025 97.67 210/215 nt Homsap IGHJ4*02 F (see comment) 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 7 13 8.7.13 [1.17.38.11] CARGGGYYFVAIDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctctggtggctccatcagtagttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatctataaaagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaagcagttctccctgaaactgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtggtggttattacttcgtcgcgattgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 21715 JY8QFUQ01DJUBW No results 21716 JY8QFUQ01A9NEQ unproductive Homsap IGHV1-3*01 F 831 87.85 188/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-8*02 F 3 8 8 X 8.8.X [0.17.38.11] CARDGYLPGNGADF## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggatacagcttcactaatcacattatccattgggtgcgccaggcccccggacaagggcttgagtgggtggggtcgatcaacgctggcaatggcaatacaagatattcacagaagttgcagggcagagtcaccatttccagggacacatccgcgagcgtcgccaacatggagttgagcagtctgagatatgaagacacggctgtatattattgtgcgagagacggctatttgcctggcaacggggctgacttttggggcccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21717 JY8QFUQ01AJLWC productive Homsap IGHV3-66*02 F 908 91.63 197/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.17.38.11] CAKLADTGEWSNRIFYFW in-frame + cctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgctctgaccagcggcgtgcaca 21718 JY8QFUQ01B3RQ2 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 875 88.24 195/221 nt 87.33 193/221 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 115 70.0 35/50 nt Homsap IGHD6-19*01 F 2 10 7 17 10.7.17 [1.17.38.11] CTNDHSMAVSAEGMLLMFR in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'AC' (2 nucleotides at position 55 to 56 in the user submitted sequence), (cause frameshift); tctctggtgcctccatgagcagtagtgcatactactggGggctgggtccgccagACcccccgggaagggggccggagtggattgggagtgtctactatggtgggagcacctactacaacccgtccctcaagagtcgggcctccatttctgtcgacacgtccaggaacgagttctccctgaggctgaactctgtgaccgccacagacacggctatgtattactgcacgaacgaccattcaatggcagtctctgctgaaggcatgcttttgatgtttcggggtccagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21719 JY8QFUQ01B9KDR productive (see comment) Homsap IGHV3-7*01 F 1017 96.77 210/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) gctctggattcagctttagtactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21720 JY8QFUQ01A3WOJ No results 21721 JY8QFUQ01CXBP9 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [2.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame + Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) gcctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21722 JY8QFUQ01B0BRD unproductive Homsap IGHV3-7*01 F 963 93.58 204/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CAREQSSRGYPLDYW# out-of-frame - in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift); cctctggattcacctttagtacttttttggtgaccngggtccgccaggctccagggaaggGggctggagtgggtggccaacataAaagcaagatggGaagtgaggcatactatgtggactctgtgaaggGgccgattcaccatctccagagacaacgccaggaactcactgtttctgcaaatgaacagcctgagaggcgacgacacggctgtctattactgtgcgagagaacaatcctcgaggggatatccacttgactactgggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagnaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21723 JY8QFUQ01A6OJI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 706 81.02 175/216 nt 80.56 174/216 nt Homsap IGHJ4*03 F 114 70.83 34/48 nt Homsap IGHD2-8*01 F 1 8 7 X 8.7.X [2.17.38.11] CARHLMVYALDV## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01A6OJI ; 8 AA in Homsap_IGHV3-23*01), and low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); gcctctggattcagcctcgccacttatagtatgagttgggtccgccaggctccaggcaaggggctggagtgggtctcagtcttatttagtactggcactgcatactacgcagactccgtgAaaaggccggttcaccatctccagagacaattccaacaacaccctatatcttcagatgaacaacatcagacctgaagacgcggccacttattattgtgcgaggcatttaatggtctacgctctggacgtctgggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 21724 JY8QFUQ01BTWL3 unproductive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.07 192/218 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDSVPRVVRGC#YHFDYW out-of-frame + stop codons Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'C' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 104 of V-REGION: 'TC' (2 nucleotides at position 218 to 219 in the user submitted sequence), (cause frameshift); cctctggattctccttcagaagttaCtcttttccactgggtccgccaggctccaggcaaggggctagagtgggtggctgttatttcacatgatggcattactaactattatgcagactccgtgcagggccgattcatcatctccagagacaattccaagaacacgctgtttctgcacatgaacagcctgagagttgaggacacggctgtttatttttTCgtgcgagagattccgtacctcgggtcgtcagaggctgcctaccactttgactattggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccga 21725 JY8QFUQ01BQQAT No results 21726 JY8QFUQ01BOQDD unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 21727 JY8QFUQ01C4Q8E unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.55 220/221 nt 10 7 X 10.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21728 JY8QFUQ01A82HJ productive Homsap IGHV3-72*01 F 953 91.96 206/224 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 10 14 8.10.14 [1.17.38.11] CARLHYSGGWYGLDVW in-frame - cctctggattcaccttcagtgaccactacatagactgggtccgccaggctccaggaaaggggctggagtgggttggccgtactcgaaataaagctaacggttacagtacagagtatgccgcgtctgtgaaaggcagattcaccgtctcaagagataactcagagaacttagtgcatctgcaaatgaacagcctgaaaagcgaggacacggccctgtattactgtgctagactgcactacagtggtggctggtacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21729 JY8QFUQ01CFHNB unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 703 80.37 176/219 nt Homsap IGHJ1*01 F (see comment) 107 67.31 35/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [2.17.38.11] CARGLGLNAVYAFDV## out-of-frame + Low V-REGION identity (80,37% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcgcttttggagattatgccatgaactgggtccgccaggccccagggaagggactggagtgggtctcaggtttgagcggtagaggcgtcagcaaatattatgcagactccgtgaggggccggttctccatttccagagacaactccgggagcgaggcagtccttcaaatgagcagcctgagagtcgaggacacggccacttactactgtgcgaggggcctagggcttaatgctgtctacgcatttgacgtctgggggacaggggaccacggtcaccgtctcctcagcatcccccgaccagccccaaagggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21730 JY8QFUQ01ARH62 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - ctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgatccagggcttcttcccc 21731 JY8QFUQ01A5GKO productive Homsap IGHV1-2*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARGVKSSAWHFDHW in-frame + tggatacaccttcatcggcaactatgttcactgggtgcgacaggcccctggacaagggcttgagtggatgggctgggtcaaccctaacagtggtagcacaaactttgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcaccacagtctccatggagctgaacagcctgagatctgacgacacggccgtgtattactgtgcgagaggggtgaagagcagtgcctggcactttgaccactggggccagggaaccctggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21732 JY8QFUQ01DB7HM unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 120 66.67 40/60 nt 8 X X 8.X.X [2.10.X.X] null + No rearrangement found gcctccggattcacctttagtagttactggatgcactgggtccagggcttcttcccccca 21733 JY8QFUQ01DK9P4 No results 21734 JY8QFUQ01CPA3N productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD2-8*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDRGCTNGACYVADFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcgggaactatagcatgaactgggtccgccacgctccagggaaggGggctggagtgggtctcctccattagtaatagaggtagtttcaaatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacgggtgtatatttctgtgcgagagatcggggttgtactaatggtgcatgctatgtcgccgacttctggggccagggaacccaggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21735 JY8QFUQ01COXPE productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 883 89.5 196/219 nt 88.58 194/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-22*01 F 3 8 8 14 8.8.14 [2.17.38.11] CARDFFIGGYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 98 to 98 in the user submitted sequence), (cause frameshift); gcctctggattcagctttttcaattatggGcatgaactgggtccgccaggctccagggagggggctggagtgggtcgcatttattagcggtgctggtGaaaaatacttactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatttcttcataggaggctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21736 JY8QFUQ01AF78T No results 21737 JY8QFUQ01B4MAM productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 994 93.78 211/225 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 142 76.0 38/50 nt Homsap IGHD2-15*01 F 2 8 10 17 8.10.17 [2.17.38.11] CAADGCPGGTCYHGFLICG in-frame - gcctctggattcactttcagtaacgtctggatgcactgggtccgccaggctccagggaaggggctggagtgggttggccgtattagaagcaaaactgctggtggggcaacagaatacgctgcgcccgtgagaggcatattctccatctcaagagatgattcaaagaacacgttgtatctgcaaatgaacagcctgaagaccgaggacacagccgtgtattactgtgccgcagatggttgtcctggtggtacctgctatcatgggtttttgatatgtgggggccaagggacaatggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21738 JY8QFUQ01AZKCA productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 8 8.7.8 [3.17.38.11] CARGAPFYDS (see Functionality comment) in-frame - Potentially, because of detected insertion/deletion, IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 48 of V-REGION: 'C' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); tgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggCaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21739 JY8QFUQ01CFD8X unproductive Homsap IGHV3-7*01 F 1049 98.17 214/218 nt Homsap IGHJ1*01 F (see comment) 89 63.46 33/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARDPYSSGRGTFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacctttagtttctattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaattcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatccgtatagcagtggccgggggacttttgactactggggccaggggaacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21740 JY8QFUQ01BGQBS unproductive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [2.17.38.11] CARGDGYDTFDYW# out-of-frame + in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); ggttcaggatacgactttcccacctactggatcggctgggtgcgccagatgccCcggcaaaggcctggagtggatggGggatgatgaatcctgaagactctgacaccagatacagtccgtccttcccaggccaggtcaccatctcagtcgacaagtccatcagcaccgcctacctgcagtggagcagcctcaaggcctcggacaccggcatgtatttctgtgcgagaggcgatggctacgatacctttgactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21741 JY8QFUQ01CCWP5 No results 21742 JY8QFUQ01CN1M1 productive Homsap IGHV3-7*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [0.17.38.11] CARGTSVDPGIDHW in-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tggattcacctttagtaattattggatgcactgggtccgccaggtttcagggagggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21743 JY8QFUQ01CDCEV productive (see comment) Homsap IGHV3-66*02 F 898 91.55 195/213 nt 90.61 193/213 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [1.16.38.11] CAKLADTGEWSNRIFYFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccgtcagtagcagcttcatgacttgggtccgccagctccaggaaagggactggagtAgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg 21744 JY8QFUQ01BZ5ZM unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDMGSGRYFGTL#DYW out-of-frame + stop codons in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); ggtctggattcatcttctTgaaaatatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcaggtatatggtttgatggaagtaatacatactatgcggactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttggaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21745 JY8QFUQ01CNIDY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 913 91.2 197/216 nt 90.74 196/216 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift); tcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21746 JY8QFUQ01CW2YY productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 915 90.91 200/220 nt 89.09 196/220 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'GG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'A' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); ggcctccggattcacctttagtagttactggatgcactgggtccgccGaagctccagGGggagggactgggtctgggtctcacggactaatgaagatgggagtatcacGaaactacgAcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21747 JY8QFUQ01B5TR2 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 866 87.78 194/221 nt 87.33 193/221 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-14*01 ORF 2 8 10 13 8.10.13 [1.17.37.11] CTADVPSPLAQNDFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 85 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) tctggattcactttcaatggcgcctggatgaactgggtccgccaggctccagggaagggtctggagtgggttgcccgtataaaaacttttggtgaaggtgggacaacagactacgctgcacccgtgaaaggcagattcgtcatctcaagagacgattcaaaaaaaggctgtatctgcagatggacagcctgagaatcgaggacatagccaagtattactgcaccgcagatgtcccgtcaccattagcgcaaaatgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21748 JY8QFUQ01A87BG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F or Homsap IGHJ4*03 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGHSYYVSSGPDYW in-frame + cctctggattcacctttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactggggccacggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaggcatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21749 JY8QFUQ01A1ISV productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21750 JY8QFUQ01B9VDC productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 936 92.63 201/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); ctctggattcaTcgttcagtagctactggatgcactgggtccgccaagctccCagggaaggggctggtgtgggtgtcacgtagtaataCcgggggggactgacacagcctacgcggactccgtgaagggccgattcaccatctcccgagacaacgggaagaacacgctgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21751 JY8QFUQ01CEUXK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 564 78.69 144/183 nt 8 8 X 8.8.X [1.17.26.X] null + No rearrangement found Low V-REGION identity (78,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcaccttcagtggttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgaattgatagttctgcgaatctcatcaaatacgcggactccgtggagggccgattcaccgtctccagagacaacgccgaaccggtgacggtgtcgtggaactcag 21752 JY8QFUQ01CBWNJ productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F (see comment) 744 82.27 181/220 nt 81.82 180/220 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 10 7 20 10.7.20 [1.17.38.11] CARQSEPANNFNDPSRYFFDTW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,27% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift); tctccgtgtctccatttccattaatgattactactGggggctggatccgccagcccccaggaaagccgctggagtggattgggactgtccattcccttgggtacaattacaacaacccgtccctcaagagtcgactcaccatttccgcagacacgtccaggaatcagatctccctgaaactgacgtctgtgaccgccgcagacacggctgtctatttctgtgcgagacagagcgagcccgccaataacttcaatgacccaagtcgttatttctttgacacttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21753 JY8QFUQ01BS8WW unknown (see comment) Homsap IGHV3-72*01 F 407 97.65 83/85 nt 8 1 X 8.1.X [2.17.X.X] null + No rearrangement found gcctctggattcaccttaagtgatcactacatggactgggtccgccaggctccagggaaggggctggagtgggttggccgtacta 21754 JY8QFUQ01CSDEG productive Homsap IGHV3-48*02 F (see comment) 734 81.65 178/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [1.17.38.11] CARSTDGYYDHW in-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattccccttcaatatatggagcatgaattgggtccgccaggctcccgggaagggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcgggtctttcccccctgggcgccctgctccagggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21755 JY8QFUQ01ADDIY unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 874 89.04 195/219 nt 87.67 192/219 nt Homsap IGHJ1*01 F 98 65.38 34/52 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [2.17.38.11] CAKDQSCIVGPCGF*LLG in-frame + stop codons in FR3-IMGT at codon 91 of V-REGION: 'CG' (2 nucleotides at position 180 to 181 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 98 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); gcctccgaattcatccttgacagttatgccatgagttgggtccgccaggccccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatCGaacaagcctaggggccgaggaGcacggccgttTtattactgtgcgaaagatcagtcctgtatagtgggaccttgtggtttttgactactgggggccaggggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21756 JY8QFUQ01CO06K productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 90.05 199/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21757 JY8QFUQ01AZZ55 productive Homsap IGHV3-7*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGYYSTGYW in-frame + ggctctcgattcaccttcagtggttattggatgaactgggtccgccagactctagggaaggggctggagtgggtggccagcataaaccaagatggaagtgagacgtcctatgtgggctctgtgaagggccgattcgccatctccagagacaacgccaagaactctctgtatctgcaaatgaatagcctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtctttccgctgagcctcctgcagcacccagcccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21758 JY8QFUQ01DXAUT unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F or Homsap IGHV3-7*03 F (see comment) 449 72.47 129/178 nt 71.91 128/178 nt 8 8 X 8.8.X [1.16.25.X] null + No rearrangement found Low V-REGION identity (72,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 58 in the user submitted sequence), (cause frameshift) ctctggattcacctctcctagatactggatgaattgggtccgccaggcttccgggaagggctggagtgggtggccaacataaagcaagacggaagtgaggaaaactttgtggactctgtgaagggccgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21759 JY8QFUQ01BMBCR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 874 89.04 195/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - gcctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21760 JY8QFUQ01AEYNO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21761 JY8QFUQ01BUAFC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggacacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21762 JY8QFUQ01ATMMU productive (see comment) Homsap IGHV3-48*02 F (see comment) 730 81.28 178/219 nt 80.82 177/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*01 F 2 8 8 10 8.8.10 [2.17.38.11] CARSTDGYYDHW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,28% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); gcctctggattccccttcaatatatggagcatgaattgggtccgccaggctccggggGAaggggactggagttgatcgcatacatcacaagtgatgaaagaaccatatactacgcagactctgtgaagggccgcttcaccatctctagagacaatgccaggaacctagtacatctggaaatgaacagcctgagggacggcgatctggctatctattactgcgcgagaagcactgatggctattacgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21763 JY8QFUQ01AEF82 productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 10 9 19 10.9.19 [0.17.38.11] CARGSSRGGNSDGVYYELDYW in-frame - ccggggacagtgtctctaccacccgtgctgcttggaactggatcaggcagtccccatcgggaggccttgagtggctgggaaggacatactacaggtccaagtggcttaatgattatgcagtgtctgtgaaaagtcgaattaccatcaatccagacacatccaagaaccagttttccctgcagttgaaatctgtcattcccgaggacacggctgtttattactgtgcaagaggttccagtcgcggggggaattctgatggggtctactatgaacttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 21764 JY8QFUQ01AXKXP unproductive (see comment) Homsap IGHV3-21*03 F, or Homsap IGHV3-21*04 F 995 95.41 208/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [1.17.38.11] CHRHGPRGWEATW##DYW out-of-frame + stop codons cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacaacctgagaaccgaggacacagccctttattactgtcaccgacacggcccccgggggtgggaagccacttggccttgactactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcaccccccaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21765 JY8QFUQ01CENHS No results 21766 JY8QFUQ01BMQAP productive (see comment) Homsap IGHV4-61*01 F 988 94.14 209/222 nt 93.69 208/222 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [2.17.38.11] CARGGSGGAYWNLIRDW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 67 of V-REGION: 'TATAATCCCCTG' (12 nucleotides at position 112 to 123 in the user submitted sequence), (do not cause frameshift); gtctctggtggctccgtcagcagagatatttactactggagctggatccggcagcccccagggaagggactggagtggattgggtatatgtatcacagagggaacactaagTATAATCCCCTGtataatccctccctcgagagtcgagtcaccatttcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggtgggtccggtggggcctactggaatttgatccgggactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21767 JY8QFUQ01C39EW productive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame - tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21768 JY8QFUQ01C1K4A No results 21769 JY8QFUQ01B50E3 unproductive (see comment) Homsap IGHV3-30*01 F 937 92.24 202/219 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [2.17.38.11] CVKK*PVLGHNR##YFDYW out-of-frame + stop codons gcctctggattcacgttcaacatttatggtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21770 JY8QFUQ01AO9MS productive (see comment) Homsap IGHV2-5*02 F 1111 95.47 232/243 nt 95.06 231/243 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD4-17*01 F 3 10 7 13 10.7.13 [9.17.38.11] CAHFSVTTPYGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 110 to 110 in the user submitted sequence), (cause frameshift); gacctcacgctgacctgcaccttctctgggttctcactcaccactactggagtgggtgtgggctggatccgtcagcccccaggaaaggccctggagtggcttgcagtcaCttttttgggatgatgatgagcgccacagcccatctctgaggagaaggctcaccatcaccaaggacatctccaaaaaccaggtggtccttacaatgaccaacatggaccctgtggacacagccacatattactgtgcacacttttcggtgactaccccatatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21771 JY8QFUQ01B8IT3 productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.52 198/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 80 to 85 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21772 JY8QFUQ01B61YA No results 21773 JY8QFUQ01DGCRI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame + cgtctggattcaccttcagtagctacggcatgcactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21774 JY8QFUQ01B949V unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 987 94.55 208/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [2.17.38.11] CVRRGDGSGQ##DAFDIW out-of-frame - stop codons agcctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaaggggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtatcgtggaactcag 21775 JY8QFUQ01CA2MY productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1085 100.0 218/218 nt 99.54 217/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 2 8 8 22 8.8.22 [1.17.38.11] CARGHCISTSCYWEIHYYYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggGggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21776 JY8QFUQ01CDL2M unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARPFSGRWCFDL## out-of-frame - Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) cctctggattcaccttcagttactcctggatgcactgggtccgccaagttccaggaaaggggccggtgtgggtctcacaaattaaaagtgatgggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctgggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21777 JY8QFUQ01CDJGM unproductive Homsap IGHV4-28*01 F, or Homsap IGHV4-28*02 F or Homsap IGHV4-28*03 F or Homsap IGHV4-28*05 F or Homsap IGHV4-28*07 F or Homsap IGHV4-39*07 F or Homsap IGHV4-4*06 F or Homsap IGHV4-55*03 P (see comment) 391 77.04 104/135 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 228 94.12 48/51 nt Homsap IGHD3-22*01 F 2 X 7 X X.7.X [X.X.38.11] CVRITMILVVI#NWFDSW out-of-frame - Low V-REGION identity (77,04% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctggtgggtcccttcagtggttactacaatccgtccctcaaaagtcgagtcaccgtgtcttcagacacgtccaagaatcagttctccctggagttgatctctgtgaccgccgcggacacggccatatattattgtgtgagaattactatgattttagtggttatttcaattggttcgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21778 JY8QFUQ01AJN2L unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVVQILGGY##DYW out-of-frame + stop codons cctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctagggggctacgattgactactggggccagggaaccccggggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21779 JY8QFUQ01CBAA4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21780 JY8QFUQ01A34CF productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 810 85.78 187/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDTGSSKFARYDGMDVW in-frame + cctctggattcagcctcagtacctctggcttgaactgggtccgccaggccccagggaagggantggagtggatctcattcatcaatagtgatggtgattacatctactacgcggagtcggtgaggggccgattcaccatctccagagacaacgccgagaagtcactgtacctgcaactgaacaacctgagagtcgaggacacggctgtgtacttctgtgcgagagataccggctcgtccaagttcgctaggtacgacggtatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgcctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 21781 JY8QFUQ01B0S2P No results 21782 JY8QFUQ01BBWB8 No results 21783 JY8QFUQ01BAECU unknown (see comment) Homsap IGHV3-7*01 F 991 94.98 208/219 nt 94.52 207/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); acctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaagccccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 21784 JY8QFUQ01B58N4 productive (see comment) Homsap IGHV4-61*02 F 815 86.24 188/218 nt 85.32 186/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-16*01 F 3 10 6 16 10.6.16 [1.17.38.11] CAIERSRSIGGDGQFDFW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 102 in the user submitted sequence), (do not cause frameshift) tctctggtggccccatcagaggcggtggtttctactggacctGggctccggcagtccgccgggaagggcctggagtggatcggacgtatttatgacagtggcagtgactacaatccttctctcaagagtcgagtcaccatgtcagtagacacgtccaagagccagttctccctgaggctgagttctgtggccgccgcagacacggccgtttacttctgtgcgatagaacgtagtagatcgattggcggagacggacaatttgacttctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21785 JY8QFUQ01DWR54 productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ1*01 F 80 61.54 32/52 nt Homsap IGHD6-25*01 F 3 8 8 11 8.8.11 [2.17.38.11] CASFACPGKWLLG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 127 to 127 in the user submitted sequence), (cause frameshift); gtctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggGggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttgcgtgtcctggaaagtggctactggggccaggggaacccttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21786 JY8QFUQ01CNGV0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcaccttTtaccaactatggcatgagctgggtccgccaggctccagggaaggGggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21787 JY8QFUQ01B3ZV0 No results 21788 JY8QFUQ01DKNDP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + ctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21789 JY8QFUQ01BSHOR productive Homsap IGHV3-7*01 F 918 91.28 199/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARGSYWHYDTFGDYW in-frame - cctctggattcaccttcagtagctatgctatgcactgggttcgccaggntccagggaaggggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21790 JY8QFUQ01BM1A9 productive Homsap IGHV1-8*02 F 822 87.38 187/214 nt Homsap IGHJ2*01 F 193 84.91 45/53 nt Homsap IGHD2-21*02 F 2 8 8 16 8.8.16 [0.17.38.11] CTTKFGSDWQSDWYFHVW in-frame + tggagacacattccccagccatgacatcaactgggtgcgacaggccactggagaagggcttgagtggatgggacggatgaaccctaagactggtgacacaagctttgcacagaagttccacgatagagtcaccatgatcagtgacacctccataagtacagtgtacatggagctgagtagcctgagatctgaagacacggccatttactattgtacgacaaaattcgggagtgactggcaatcggactggtacttccacgtctggggccgtggcacctcggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21791 JY8QFUQ01BY5B0 productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 923 91.74 200/218 nt 90.37 197/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 1 8 8 12 8.8.12 [1.17.38.11] CARRDVGLHAFDLW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'C' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift); gttctggatccaattttaactacgactggatcggctgggtgcgccagatgCcccggtaaaggcctggagtgGgatgggaatggtctatgttggtgactctgatgctagatacagcccgtcctCcccaaggccaggtcaccatctcagccgacaagtccatcaacaccgcctacctgcagtggagtagcctgaaggcctcggacaccgccatgtattactgtgcgagacgggacgtaggtttacatgcttttgatctgtggggccaggggacaatggtcagcgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgccctgcctggtccagggcttcttcccccc 21792 JY8QFUQ01AO74U productive (see comment) Homsap IGHV3-7*01 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [1.17.38.11] CATDDSNGWDEVADYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagCtccccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaattcattgtatctgcagatgaacagcctgagaggcgaggacacggctgtctattactgtgcgacagatgatagtaatggctgggacgaggtcgctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21793 JY8QFUQ01B3L3F productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21794 JY8QFUQ01B09FB No results 21795 JY8QFUQ01BWFI9 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctaagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21796 JY8QFUQ01B083I unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found gagttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgcccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 21797 JY8QFUQ01CPFCW No results 21798 JY8QFUQ01BBMA6 productive (see comment) Homsap IGHV4-61*02 F 656 90.06 145/161 nt 89.44 144/161 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 X 7 13 X.7.13 [X.8.38.11] CARQGDSSGPWNDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 44 to 44 in the user submitted sequence), (cause frameshift); ggaagggactggaatggattgggcgcatgtctgccagagggggAcagcaactacaacccctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaaggggatagtagtggaccctggaatgactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21799 JY8QFUQ01B45A1 productive Homsap IGHV3-7*03 F 1031 97.25 212/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARGYSYGCFDYW in-frame + cctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagaggatacagctatggctgctttgactactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagtgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21800 JY8QFUQ01BKZZ2 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - cctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgaagggccggttcaccatctccagagacaactccaacaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21801 JY8QFUQ01BG0RX unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt 93.12 203/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggGggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactgggggccagggaacccgtggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21802 JY8QFUQ01ACXSL productive (see comment) Homsap IGHV4-34*10 F 809 86.51 186/215 nt 85.58 184/215 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD4-23*01 ORF 2 8 7 16 8.7.16 [1.17.38.11] CARNTNYGGNSGDYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AA' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); tgtctggtgagtGccttcactaattactactggagctggatccgccagtcccccaggaaAAgggtctggagtggcttggggaggtccatcatagtggacgcaccgactacaacccgtccctcaagagtcgaatcaccatgtcgttagacacgtccgaaaatcagttctccctgaagttgacttctttgaccgccgcggacacggcagtatattattgtgcgagaaataccaactatggtggcaattccggggactactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21803 JY8QFUQ01AZCLU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt 95.41 208/218 nt Homsap IGHJ1*01 F (see comment) 134 73.08 38/52 nt Homsap IGHD3-10*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGAAVALTPG in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggGggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtgcggcagttgctttaactcctgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21804 JY8QFUQ01BS2II productive (see comment) Homsap IGHV4-61*02 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 9 7 14 9.7.14 [1.16.38.11] CAREPQSNAWYYFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 34 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 39 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) tctctggtggctccgtcaacatggtaattctgactgagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21805 JY8QFUQ01CYFA7 unknown (see comment) Homsap IGHV3-64*01 F, or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 89 51.88 69/133 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons tctggattcacctttaacatgtatgtcatgcactggttccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21806 JY8QFUQ01B4Q5E No results 21807 JY8QFUQ01AMQ7L unknown (see comment) Homsap IGHV3-7*02 F 83 55.29 47/85 nt 8 1 X 8.1.X [2.17.X.X] null + No rearrangement found gcctctggtttcagcttaagtgactattggctgccctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21808 JY8QFUQ01AKL4Q unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 71 to 71 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccaactatggcatgagctgggtccgccaggctccaggGgaaggggctggagtGgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggcagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21809 JY8QFUQ01BGI0O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 909 91.24 198/217 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD2-2*01 F 3 8 8 20 8.8.20 [1.17.38.11] CAKTVVPAAPNRFYYYYGLDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) ctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgattttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21810 JY8QFUQ01BV8FF productive Homsap IGHV3-13*01 F 885 90.65 194/214 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-12*01 F 3 8 7 10 8.7.10 [1.17.38.11] CATISDYRFEFW in-frame - ctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccgacgacacggctatttattactgtgcgaccattagtgactaccgatttgaattctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21811 JY8QFUQ01A7ZX0 unproductive (see comment) Homsap IGHV4-61*02 F 915 90.91 200/220 nt 90.45 199/220 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-22*01 F 3 10 7 X 10.7.X [1.16.38.11] CAREK**SV#NWFDPW out-of-frame - stop codons in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) tctctggtgactccatcaccagtggtaattattattggagttggatcggcagcccgccgagaagggactggagtggattgggcgtatctccatcggtgggatcaccaactacaatccctccctcaagagtcgagtcaccatactattagacacgtccagcaaccggttctccctgaagctcagctctgtgaccgccgcagacacggccgtgtattactgtgcgagagaaaagtagtgatccgtcccaattggttcgacccctggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21812 JY8QFUQ01A25XG No results 21813 JY8QFUQ01C3UGX productive (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [2.17.38.11] CTRQTGNYYYFGVDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'A' (1 nucleotides at position 160 to 160 in the user submitted sequence), (cause frameshift); gcctctggattcctcttcagtagctttaacatgaactgggtccgccacgttccagggaagggtctggagtgggtttcatacattaatagtagaggtactaacatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaggAaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggccgtatactactgtacgagacaaactgggaattattattacttcggtgtggacgtctggggccaagggactacggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21814 JY8QFUQ01B9QOB productive (see comment) Homsap IGHV1-18*01 F 840 88.32 189/214 nt 87.85 188/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 14 8.8.14 [0.17.38.11] CVRDSRHKFGAHFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggttacaccttgaccagcactggtttcagttgggtgcgacaggCcccctggacaagggctcgagtggatggcatggatcagcgtttacgatgatgacacaagttatgcacagaagtttcagggcagggtcaccctgaccacagacacactcacgaacacagcccacatggagctgaggagcctgaattctgacgacacggccgtgtacttctgtgtgagagatagtcgacacaagtttggtgcccactttgacctctggggccagggaaccctggtcatcgtcgcctcagcttccaccaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21815 JY8QFUQ01DPTEF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 878 89.45 195/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctgggctcagcgtcagtaactaccgcatgggctgggtccgccaggctccagggaaggggctggtttgggtctcacgtgttaatggtgatgGggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21816 JY8QFUQ01DHC6Q unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt 91.28 199/218 nt Homsap IGHJ3*02 F 178 84.0 42/50 nt Homsap IGHD7-27*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDQSLGMPEA#FDIW out-of-frame - stop codons in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcgctatagcatgaactgggtccgccaggGctccagggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatatTtactgtgcgagagatcaaagtctggggatgcccgaggctttttgacatctggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21817 JY8QFUQ01B31VW unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 935 93.02 200/215 nt 92.56 199/215 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [0.17.38.11] CARDCDSGECNFDYW in-frame - stop codons in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctgattcagcttcagtacctaGtaacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21818 JY8QFUQ01ARWZ0 productive Homsap IGHV3-7*01 F 959 93.58 204/218 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt 8 8 9 8.8.9 [1.17.38.11] CTTTLVWFGEL (see Functionality comment) in-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21819 JY8QFUQ01B3JUB productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 972 94.47 205/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 111 68.63 35/51 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAEKKHYNSGTYLYNFDYWG in-frame - ctctggattcacctttagcaactttgccatgacctgggtccgccaggctccagggaggggactggagtgggtctcaactattagtggtagtgatggtagcacatacttcgcagactccgtgaagggccgattcaccatctccagggacaatttcaagaacacgctgtatctgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcggaaaaaaaacattataattcggggacttatttatacaactttgactactgggggccgggggaacccctggtcaccgtctcctcagcatcccccgcagccccaaggccagttcctccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 21820 JY8QFUQ01ANE3L productive (see comment) Homsap IGHV3-30*01 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); cctctggattcacgttcaacatttatgGgtctacactgggtccgccaggctccaggcaaggggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21821 JY8QFUQ01B43FE unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 959 93.58 204/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDRRGYSYEMDY## out-of-frame + cctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21822 JY8QFUQ01CT6XX productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21823 JY8QFUQ01A95B1 unknown (see comment) Homsap IGHV1-2*02 F 494 85.71 114/133 nt 8 8 X 8.8.X [0.17.11.X] null + No rearrangement found tggatacattttcaccagctactatttacactgggtgcgccaggccgctggacaagggcttgagtggatgggatacatggaccctcatagtggtgacacaagctttgcaaagaaatttcagggcagggtaacc 21824 JY8QFUQ01CX6GI productive Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 1105 100.0 222/222 nt Homsap IGHJ6*01 F (see comment) 108 63.49 40/63 nt Homsap IGHD6-6*01 F 2 8 10 16 8.10.16 [1.17.38.11] CTRRSIADNFYYYGMDVW in-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) tctgggttcaccttcagtggctctgctatgcactgggtccgccaggcttccgggaaagggctggagtgggttggccgtattagaagcaaagctaacagttacgcgacagcatatgctgcgtcggtgaaaggcaggttcaccatctccagagatgattcaaagaacacggcgtatctgcaaatgaacagcctgaaaaccgaggacacggccgtgtattactgtactagacggagtatagcagataacttctactactacggtatggacgtctgggggccaagggaccacagtcaccgtctcctcagcttccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21825 JY8QFUQ01B2OA5 productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD6-6*01 F 1 8 8 20 8.8.20 [1.17.38.11] CARDDSRLWSSSFNHYFAMDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); gtctggattcaccttcagttcctatgccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtttgatggaagtaataaatactacgcagactctgtgaagggccgattcaccgtctccagagacgatgccaagaattcacttTtttctgcaaatggacagcctgagagacgacgacacggctgtatattactgtgcgagagacgattcacggctgtggagctcgtcatttaaccactatttcgctatggacgtctggggccaagggaccaccgtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 21826 JY8QFUQ01B1VUD productive Homsap IGHV3-11*01 F (see comment) 765 83.87 182/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARDLVGSIGSW in-frame + Low V-REGION identity (83,87% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaaggggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctctgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccaagggcccatcggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21827 JY8QFUQ01CVGHB productive Homsap IGHV3-66*02 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 7 16 8.7.16 [2.17.38.11] CAKLADTGEWSNRIFYFW in-frame - cagcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcggtggtaacacatactacgcagactccgtgaagggccgattcaccacctccagagacaattccgagaacactctgtatcttcaaatgaacaacctgagacctgaggactcggctgtgtattattgtgcgaaattggcggatactggagagtggagcaaccgcatcttttatttctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcgggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21828 JY8QFUQ01A4E73 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 906 90.45 199/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [2.17.38.11] CARDLYGADDLW in-frame + aacctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttcccccc 21829 JY8QFUQ01BB4SZ productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21830 JY8QFUQ01B9PP2 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 893 89.59 198/221 nt 88.69 196/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 3 9 7 X 9.7.X [2.17.38.11] CVRPDNYFGSGEC#WMDPW out-of-frame - in FR2-IMGT at codon 55 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 38 of V-REGION: 1 nucleotides (from position 36 in the user submitted sequence), (cause frameshift) gtctctggtggctccatcagcagtgataatttctatggggctggatccgccagcccccagggaagggactgcatggattggggaCttttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcgggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21831 JY8QFUQ01C46LG unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 975 95.33 204/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [0.17.38.11] CAGDRGPVLG*FI*AK#YGLDVW out-of-frame - stop codons tggatacaccttcaccaactactatcttcactgggtgcgacaggcccccggacaagggcttgagtggatgggacggatcaacccaaacagtggtggcacaacctatgcacagaagtttcagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgagcaggctgagatctgacgacacggccgtctattactgtgcgggagatcggggtccggttttggggtgattcatataggccaaatctacggtctggacgtctggggccaagggaccacagtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21832 JY8QFUQ01BEZGO No results 21833 JY8QFUQ01BRFS8 productive (see comment) Homsap IGHV4-4*07 F 890 90.7 195/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-24*01 ORF 3 8 7 13 8.7.13 [1.17.38.11] CARDFGGSYNLVAYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGATTC' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 101 to 101 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagtagTGATTCtcactactggagttggatccggcagcccgccggGgaagggactggagtggattgggcgtgtctacgccagtgGggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagtggcctactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgcaaccggtgacggtgtcgtggaaact 21834 JY8QFUQ01CYBYL unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F (see comment) 417 82.11 101/123 nt 8 8 X 8.8.X [1.17.6.X] null - No rearrangement found Low V-REGION identity (82,11% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggatttgccctcagtgactatgccatgcactgggtccgccaggctccagggaaggggctggagtggattgcatacattagtgtttctacttacaccattttctacgcagagtctgtta 21835 JY8QFUQ01DJK0S No results 21836 JY8QFUQ01BN7DA productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 962 92.41 207/224 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 1 8 10 10 8.10.10 [1.17.38.11] CTHLREEMSYEW in-frame + cctctggagtcaaattcagaaacgcctggatgaattgggtccgccaggctccagggaaggggctggagtgggttggccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaacacgttttatctgcaaatgaatagcctaaaaaccgaagacacagccgtctattactgtacccacttgcgagaagagatgtcttacgaatggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21837 JY8QFUQ01CD92H productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-18*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVRHTAMERGDYW in-frame - gttctggatatgactttatcaactactggatcggctgggtgcgccagatgcccgggagaggcctggaatggatgggaatcatctttcctgatgactctgatgccagatatagtccgtccttccagggccacgtcaccatctcagccgacaagtccacaagcaccgcctacctggagtggagcagcctgaaggcctcggacaccgccatctactactgtgtgagacatacagctatggagaggggtgactactggggcccgggaaccctggtcaccgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21838 JY8QFUQ01CBOGY unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 X 8.8.X [1.17.38.11] CARETLPPWCWG#FDNW out-of-frame + stop codons ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactccccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcatagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact 21839 JY8QFUQ01AM5NO productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + cctctggattcacctttagccactttgccgtgacctgggtccgccaggctccagggaagggtctggaatgggtctcaactattagcggtagtgatggtagcaagtactacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacaccctatatctgcaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21840 JY8QFUQ01CQ1OX productive (see comment) Homsap IGHV4-34*06 F (see comment) 682 80.19 170/212 nt 79.72 169/212 nt Homsap IGHJ4*02 F (see comment) 168 83.33 40/48 nt Homsap IGHD2-15*01 F 2 7 7 14 7.7.14 [1.17.38.11] CSRGGQSAGWHSFEAW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (80,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT, from codon 38 of V-REGION: 2 nucleotides (from position 27 in the user submitted sequence), (cause frameshift) tccatggtgggtccctcagggttaccctggacctggatccgccacaccgcagagaagggactggagtggattggtcaaatcaatagtgatggaaggacaacctacaactcggccctcatgggtcgagtcaccatttcaacagacacatccaagaatcagttctcgctgactgtggtttctgttgtcgccgcggacacggcaatgtattattgttcgagaggaggccaaagtgctggctggcactcctttgaagcctggggccagggaacccaggtaatcgtcacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21841 JY8QFUQ01B4E2J productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1045 97.72 214/219 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [2.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - gcgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21842 JY8QFUQ01AIYNJ productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 899 91.16 196/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - cttctgggttcaccgtcagtagcaagttcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatatccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21843 JY8QFUQ01DF3OF No results 21844 JY8QFUQ01BV2DA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKGIVGDTFFDY## out-of-frame - cctctggattcacctttagtaattatgccctgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggaatcagtagtagtggtgagatcccaaactacgcagactccgtgaagggccggttcaccatctccagagacaattccaggaacacgctgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaaagggatagtgggagacactttctttgactactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21845 JY8QFUQ01BDMNQ productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1085 97.8 222/227 nt 96.92 220/227 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 3 10 9 19 10.9.19 [1.17.38.11] CTRGSSRGGRYDENYYELDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 154 to 154 in the user submitted sequence), (cause frameshift); tctccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtCccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacCccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcggggggagatatgatgagaactactatgagctggacttctggggccagggaaccctggtcaccgtctcctcagnatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21846 JY8QFUQ01CEB10 productive (see comment) Homsap IGHV3-13*01 F 899 91.16 196/215 nt 90.7 195/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD4-11*01 ORF 3 8 7 17 8.7.17 [1.17.38.11] CAREVTRLTVPYYLYFDLW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 97 of V-REGION: 'G' (1 nucleotides at position 192 to 192 in the user submitted sequence), (cause frameshift); tctctggaatcaccttcagtgactccgacatgcactgggtccgccaagctccaggagaaggtctggagtgggtcgcagctattggaactgctggtgatacatactatgcagactccgtgaagggccgattctccattaccagagagaatgccaagaactccttgtttcttcaaatgaacagcctgagagccGggggacacggctgtttattattgtgcaagagaggtgactagacttactgtcccctattacttatacttcgatctctggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21847 JY8QFUQ01B8YTR No results 21848 JY8QFUQ01B61PE productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F (see comment) 785 84.16 186/221 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-9*01 F 2 10 7 11 10.7.11 [1.17.38.11] CARILDGYFFDPW in-frame - Low V-REGION identity (84,16% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcgacactcaaaattactactggggctggattcgccagcccccagggacgggactggagtgggttggcagtgtccgctatggcgagagcacctattacaacccgaccctcaaaagtcgactcaccatatccatagacacgtccaggagccagttatccctgagactgagttctgtcaccgccgccgacacggcagtttactactgtgcgaggatcttggatggttacttcttcgacccctggggccagggaacccacgtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21849 JY8QFUQ01B53DN productive (see comment) Homsap IGHV3-7*02 F 909 91.24 198/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 8 8 9 8.8.9 [1.17.38.11] CARDQVTEDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'C' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctctggattCcttttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaAaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 21850 JY8QFUQ01ATY9J No results 21851 JY8QFUQ01BE8PV No results 21852 JY8QFUQ01B1MG0 No results 21853 JY8QFUQ01CU1MK productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1004 95.87 209/218 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CAKDGARGGGSCFNSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21854 JY8QFUQ01CGDGF productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 878 89.45 195/218 nt 88.53 193/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-10*01 F 1 8 8 11 8.8.11 [1.17.38.11] CARVGTFNWFGPW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift); cctctggattcaGtttttgcagattatggcatgggctgggtccgccaacttccagggaaggggctggaatgggtcggtggtgttaattggaatgGggggcagcgcaggttatgcagtctctgtggagggccgattcatcatctccagagacaacggcaagaagtccctgtatttgcaaatgaacagtctgagagtcgaggacacggccgtgtattactgtgcgagagtcggcacgttcaactggttcggcccctggggccagggaacgctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 21855 JY8QFUQ01DK22N unproductive Homsap IGHV1-2*02 F 903 91.59 196/214 nt 91.12 195/214 nt Homsap IGHJ5*02 F (see comment) 174 82.35 42/51 nt Homsap IGHD2-2*01 F 1 8 8 X 8.8.X [0.17.38.11] CARDWGWEVRTA#DNW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tggatacatcttcaccggctactattTtgcactgggtgcgacaggcccctggacaagggcttgagtggatgggatacatcgacccttacactggtgacacaaattatgcacagaggtttcagggcagggtctccatgaccagggacacgtccatcagtacagcctacatggaactgaacaggctgatgtctgacgacacggccatgttttactgtgcgagagattgggggtgggaagtacgcaccgctagacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtctcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21856 JY8QFUQ01AOB98 No results 21857 JY8QFUQ01BLR4V productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 822 85.65 191/223 nt 85.2 190/223 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-10*02 F 2 10 7 11 10.7.11 [2.17.38.11] CVRHVRRFWFDPW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 34 of V-REGION: 'C' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); gtctctaatgggctccatcagcCggaagtgtttactactgggcctggatccgccagcccccagagaagggtctggagtacattggaagcatcttttatagtgggagcacttacttcaatccgtccctcaagagtcgagtcaccctatccgtagacacgtccaggaaccagttctccctgaggctgaagtctgtgaccgccgcagacacggctgtttattattgtgtgagacatgttcgacgattctggttcgacccctggggccagggaaccctggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21858 JY8QFUQ01AT8N2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); ctccggattcaccttTtagtagtttctggatgcactgggtccgccaagttccagGgggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatcccccgaccagccccaaggtcttccccgctgagccctcgacagcaccccccccaaagatgggaacgtggtcgtcgcatgcctggtcccaggggcttcttcccccca 21859 JY8QFUQ01B15PF productive (see comment) Homsap IGHV4-4*07 F 796 85.65 185/216 nt 84.72 183/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 8 7 18 8.7.18 [2.17.38.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'CAGTGG' (6 nucleotides at position 21 to 26 in the user submitted sequence), (do not cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'CG' (2 nucleotides at position 100 to 101 in the user submitted sequence), (cause frameshift); gtctctggaggctccatcagCAGTGGaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtCGgggggtgtcgactacaacccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 21860 JY8QFUQ01A62EH productive Homsap IGHV3-48*01 F 1000 95.43 209/219 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARERGNSYGEIDYW in-frame - gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggccagggaaccctggtcaccgtctcctcagcttccaccaaggggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21861 JY8QFUQ01BWYQ7 productive (see comment) Homsap IGHV4-61*02 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-22*01 F 2 8 7 15 8.7.15 [1.17.37.11] CSRSLPRGYYYYGVGIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'TGGAAA' (6 nucleotides at position 23 to 28 in the user submitted sequence), (do not cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 110 in the user submitted sequence), (cause frameshift) tctctggtggctccatcggtagTGGAAAttattactggagctggattcgacagaccgccggaaagggactggagtggattgggcggatatatagtactgggagcaccgactacaaccctccctcaacagtcgagtcaccttgtccatggacacgtccaagaaccagttctccctgaaactgggctctgtgaccgccgcagacacggccgtctattactgttccaggtctcttccacgaggctactactactatggtgtgggcatctggggcccagggaccacggtcgtcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21862 JY8QFUQ01B0YB2 unproductive Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 8 X 8.8.X [1.17.38.11] CTTTLVWFGGV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 41 of V-REGION: 'A' (1 nucleotides at position 36 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'A' (1 nucleotides at position 46 to 46 in the user submitted sequence), (cause frameshift); ttctggattcacgtttagagactattggatgagttAgggtccgccAaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcgggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21863 JY8QFUQ01BD1TQ No results 21864 JY8QFUQ01BD0RY unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F 169 58.78 77/131 nt 8 7 X 8.7.X [1.17.10.X] null + No rearrangement found ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 21865 JY8QFUQ01DW455 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 91 51.82 71/137 nt 8 8 X 8.8.X [1.17.11.X] null + No rearrangement found stop codons cctctggattcagctttagcaactttgccatgacttgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccga 21866 JY8QFUQ01CAEH2 unproductive (see comment) Homsap IGHV4-59*03 F 895 90.74 196/216 nt 88.89 192/216 nt Homsap IGHJ5*02 F (see comment) 138 74.51 38/51 nt Homsap IGHD3-22*01 F 3 8 7 X 8.7.X [2.17.38.11] CARGHFDSSGYSNPLDH## out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 41 of V-REGION: 'TGG' (3 nucleotides at position 38 to 40 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'CG' (2 nucleotides at position 63 to 64 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 51 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'AGCGGG' (6 nucleotides at position 97 to 102 in the user submitted sequence), (do not cause frameshift); gtctctggtgtctccatcagtagtttctactgggagtTGGgatgagggcagcccccaggggaCGgggactggGagtggattggatatgtccatggcAGCGGGagtgggagcaccaactccaacccctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctttccca 21867 JY8QFUQ01AEPDI unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 991 94.98 208/219 nt 94.06 206/219 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD2-8*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDRGCGNGACHVADY## out-of-frame + in FR2-IMGT at codon 50 of V-REGION: 'CC' (2 nucleotides at position 64 to 65 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtaactatagtatgaactgggtccgccaggctccagggaaggggCCctggagtgggtctcatccatcagtagtggtggtagtttcaAaacaccacgcagactcagcgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattattgtgcgagagatcggggttgtggtaatggtgcatgccatgtcgccgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21868 JY8QFUQ01ATI3N No results 21869 JY8QFUQ01ANKC4 productive (see comment) Homsap IGHV3-11*01 F (see comment) 774 84.33 183/217 nt 83.87 182/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD5-12*01 F 1 8 8 10 8.8.10 [1.16.38.11] CARDLVGSIGSW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cctctggattcacatttggtgactacgtcatgacttggatccgccaggctccagggaagggctggagtggatttcgtacatcaccactgatggttctttgatagaatatgcagaatctgtgaagggccggttcaccatttccagggacaacgccaagaactcactgtggctgcagatggacaacctgagagtcgacgacacggccgtttattactgtgcgagggacctcgtgggttccattgggtcctggggccagggaaccctggtcgtcgtctcctcagcctccaccagacggtccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21870 JY8QFUQ01C0TUQ productive Homsap IGHV3-30*01 F 878 89.45 195/218 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD2-2*02 F 2 8 8 11 8.8.11 [1.17.38.11] CACGHMRDGYDVW in-frame - cctctggattcaccttcagtgcctttactatgcactgggtccgccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21871 JY8QFUQ01ABDZ0 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 43 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift); ctctggattcacctttagtagttttgccatgacctgggtccGgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21872 JY8QFUQ01BSSMW unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 989 93.75 210/224 nt 92.41 207/224 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 3 10 9 X 10.9.X [0.17.38.11] CARGGDYYDSGGLDY## out-of-frame - in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); tcggggacagtgtctctagcagcagtgttgtttggaactggGatcaggcagtcCcccattgagaggccCttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21873 JY8QFUQ01BBLDK unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 186 97.44 38/39 nt 8 X X 8.X.X [2.3.X.X] null + No rearrangement found gcctctggattcatcttcagtagctactggatgcactgg 21874 JY8QFUQ01BEFQG productive (see comment) Homsap IGHV3-73*01 F, or Homsap IGHV3-73*02 F 818 86.98 187/215 nt 85.58 184/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-22*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARADYYDTSAYYLDAFDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 187 to 187 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 60 of V-REGION: 8 nucleotides (from position 93 in the user submitted sequence), (cause frameshift) ctctgggtacagcttcggaggctcttgtttgcactgggtccgccaggcTttccgggaaaggactggagtgggttggccgtgtgcggaaggcagggcgcgacaacatacgctgcgtcggtgaaaggcaggttcctcatctccagagatgatccagcgaacacggcttatctggaaatgaacagcctgAaaaaccgaggacacggccgtctattactgtgctcgcgcagattactatgatactagtgcttattatctcgatgcttttgatatctgggccagggggacaattgtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21875 JY8QFUQ01BXPJG No results 21876 JY8QFUQ01B4LZY No results 21877 JY8QFUQ01ASUXV productive (see comment) Homsap IGHV4-61*02 F 956 92.76 205/221 nt 92.31 204/221 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 10 7 14 10.7.14 [1.17.38.11] CAREPQSNAWYYFDHW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); tctctggtggctccgtcaacagtggtaAttttctactggagctggatccggcagcccgccgggaagggactggagtggatagggcgtatctatgccagtgggagcaccaactacaacccctccctcaagagtcgaatcaccatatcagcagacacatccaagaatcagttctccctgaggctgagttctgtgaccgccgcagacacaggcgtttattattgtgcgagagaaccacaaagcaatgcctggtactactttgaccactggggccggggagccctggtcaccgtctccacagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21878 JY8QFUQ01BD538 unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 977 94.5 206/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 97 66.0 33/50 nt Homsap IGHD3-10*01 F 3 8 8 X 8.8.X [1.17.38.11] CVRRGMVAGRYDAFDI## out-of-frame + cctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctgggggccgagggactatggtcaccgtctctccagcctcaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21879 JY8QFUQ01ANHZW productive (see comment) Homsap IGHV4-61*02 F 972 90.64 213/235 nt 89.36 210/235 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-10*02 F 3 10 7 16 10.7.16 [6.16.38.11] CAREHSRTMGGARELDSW in-frame - Potentially, because of detected insertion/deletion in FR1-IMGT at codon 26 of V-REGION: 'C' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 43 to 43 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) ccctcacctgcactgtcCtctggtggccccatcagcagtggtGacttactactggacttggatccggcaggccgccgggagggactggagtggatcggacgtgtttatattagtgggagcactacctacaatccctccctcaagagtcgaatcaccatatcactagacacgtccaagaaccagatcttcctgaagttgaggtctgtgaccgccgctgacacggccgtatattactgtgcgagagaacatagtaggacgatgggcggggcgagagagcttgactcctggggcctgggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21880 JY8QFUQ01A9M6A unproductive Homsap IGHV3-7*01 F 1007 96.74 208/215 nt 96.28 207/215 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [0.17.38.11] CARNTPAYWELSGD## out-of-frame + in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); ctggattcacctttaggagttattggatcagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaccCcagatggaagtgagaaatactatgtggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatggacagcctgagagccgaggacacggctgtgtattactgtgcgcgaaatacaccggcgtattgggaactatcaggtgactggggtccagggaaccctggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaaggatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21881 JY8QFUQ01CTIHR No results 21882 JY8QFUQ01BTGOM unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 265 100.0 53/53 nt 98.11 52/53 nt 10 X X 10.X.X [1.6.X.X] null + No rearrangement found in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactggGggctggatccgccag 21883 JY8QFUQ01DXGB9 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 913 91.67 198/216 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASDLGGQKSY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tcaggattcaccttcagtagatactggatgcactgggtccgccaagctccagggaaggggccggtgtgggtctcacgtactaatgaagatggcacccacataaattacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgtatttgcaaatgaacagtctgagagccgaggacacggctgtctattactgtgcaagcgatttgggtggtcagaaaagttactgggggccagggagtcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21884 JY8QFUQ01A4UYU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.45 195/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 8 8.8.8 [1.17.38.11] CAQRNSFDYW in-frame - cctctggattcacctttaacacctatgccatgaactgggtccgccaggctccagggaagggactggagtgggtttcaggtattagtgggagtggtgatgccgtaaactacgcagactccgtgaggggccggttcaccatctcccgagacaactccaagaatatattgtatctgcaaatggacagcctgagagccgaggacacggccatatattactgcgcgcaacgaaattccttcgactactggggccagggaaccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21885 JY8QFUQ01B0S0Q unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 279 60.1 119/198 nt 10 9 X 10.9.X [1.17.29.X] null - No rearrangement found stop codons Low V-REGION identity (60,10% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tccggggacagtgtctctagcaacagtcctgcttgagactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 21886 JY8QFUQ01AF30Y productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 872 89.77 193/215 nt 87.91 189/215 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [1.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'C' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); ctctggggttcaccgtcagtagcaagttcatgagctgggtccgccaggGgtccagggaaggggctggagtggGgtctcagGttacttatcctgCatggtactacacattatagagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgc 21887 JY8QFUQ01BKUFH unproductive Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*05 F 960 93.18 205/220 nt 92.27 203/220 nt Homsap IGHJ5*02 F 93 64.71 33/51 nt Homsap IGHD4-23*01 ORF 3 9 7 X 9.7.X [2.17.38.11] CASHGGKYFPQ## out-of-frame + in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'C' (1 nucleotides at position 174 to 174 in the user submitted sequence), (cause frameshift); tgtctctggtggctccatcagcagtagtaactggtggagttgggtccgccagcCccccagggaaggggctggagtggattggacaaatccatcatggtgggggcaccaattacaacccgtccctcgagagtcgagtcactatatcagtagacaagtccaagaaccacctctccCctgaccctgaactctgtgaccgccgcggacacggccgtttatcactgtgcgagccacggtggtaaatacttcccgcagtggggccagggcacccctggtcaccgtctcctcagcatcccccggaccagcccccaaggtcttcccgctgagcctcgacagcacccccccctaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 21888 JY8QFUQ01DWIIJ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 97.25 212/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [2.16.38.11] CARDLTGYSSERNYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gcctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaagggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaacgaaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21889 JY8QFUQ01ADED3 productive Homsap IGHV3-13*01 F 961 94.84 202/213 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [1.17.38.11] CARGSSKAYNWFDPW in-frame + tctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21890 JY8QFUQ01AR8QA unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 2 8 8 X 8.8.X [1.17.38.11] CARDRLTISALDY## out-of-frame + in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 177 to 177 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaAatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactgggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 21891 JY8QFUQ01B1JAF productive Homsap IGHV4-4*07 F 818 86.98 187/215 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame + tctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 21892 JY8QFUQ01AQ55A productive (see comment) Homsap IGHV4-61*02 F 938 91.86 203/221 nt 90.5 200/221 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 1 10 7 16 10.7.16 [1.17.38.11] CARATLSDVDTPLGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'T' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 120 to 120 in the user submitted sequence), (cause frameshift); tctctggtgtctcaatcacgagtggaagtcactactggaattggattcggcagCcccgccgggaagggaccggagtggattgggcgTtttctataccagtgggagcaccaactacaaccCcctccctcaagagtcgagtcaccgtatcagcagacacgtccaagaaccggctctccctgaagctgagatctttgaccgccgcagacacggccgtttattactgtgcgagagcaaccttgtctgacgtggatacacctttgggctttgactactggggccagggaatcttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21893 JY8QFUQ01BZZ8D productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21894 JY8QFUQ01ARR9X unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1031 97.25 212/218 nt 96.79 211/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD1-26*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKEFGEGP*LGTTTSTFTT## out-of-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcacgttcagtggctatggcatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcagttgtatcatatgatggaagtaataaatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctctctctgcaaatgaacagcctgagagctgaggacacggctgtatattactgtgcgaaagaatttggggagggcccctgactgggaactactaccagtactttcactactgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21895 JY8QFUQ01DOYAQ unproductive Homsap IGHV3-7*01 F 986 94.95 207/218 nt 94.5 206/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARSGSGSHL#DYW out-of-frame + in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 22 to 22 in the user submitted sequence), (cause frameshift); tctctggattcacctttagtaGgtttttggatgacctgggtccgccagggtccagggaaggggctggagtgggtggccaacataaagcaagttggaaatgagagatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatctgcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaagtggtagtgggagccacttaggattactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21896 JY8QFUQ01AY3KG No results 21897 JY8QFUQ01AQW6B productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F or Homsap IGHV5-51*04 F 905 90.83 198/218 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARRSYCGGDCYPSYWYFDLW in-frame - ggtctggatacatctttaatatccactggatcgcctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtaactctgagaccaaatatagcccggccttccaaggccaggtcaccatctcagccgacaggaccaccaataccgcctacctgcagtggcgcggcctgaaggcctcggacaccgccatgtattactgtgcgagacggtcatattgtggtggtgactgctatcctagttactggtacttcgatctctggggccgtggctccttggtcacggtctccgcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21898 JY8QFUQ01COEKL No results 21899 JY8QFUQ01BSH4H unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 222 87.72 50/57 nt 8 X X 8.X.X [1.9.X.X] null + No rearrangement found cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccaggga 21900 JY8QFUQ01DP2RP productive (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F 897 91.94 194/211 nt 91.47 193/211 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 7 8 16 7.8.16 [X.17.38.11] CTRGIAVGASHEASFDHW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 10 in the user submitted sequence), (cause frameshift) gattcagcttgatgattttgtcatgcactgggtccggcaagttccagggaagggcctggagtgggtctcaagtattacttggaatagtggtaagattgtctatgcggactctgtgaagggccgattcaccatctccagagacaacgcccagaactccctgtatctgcaaatgaacagtctacttactgaggacacggccttatattactgtacaaggggtatagctgtaggtgcctcccacgaggcgagttttgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21901 JY8QFUQ01BVFVQ unknown (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1015 95.5 212/222 nt 95.05 211/222 nt 8 10 X 8.10.X [1.17.37.X] null + No rearrangement found in FR3-IMGT, from codon 96 of V-REGION: 2 nucleotides (from position 198 in the user submitted sequence), (cause frameshift) cttctggattcacctttggtgattatagtatgagttggttccgccaggctccagggaaggggctggagtggatcggtttcattagaagcaaagctgatgatgggacaacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattccaaaagcatcgcctatctgcaaatgaatagcctgaaaccgggacacagccgtgtattactgtactagagataaccctccattgcgatctttggagtggttacctttgactcctgggccagggaaccctagtcaagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcancacccagccagatgggaacgtgtcatcgctgcctggtcagggcttcttcc 21902 JY8QFUQ01BD4IE productive (see comment) Homsap IGHV3-11*01 F 973 94.06 206/219 nt 93.61 205/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD4-17*01 F 2 8 8 15 8.8.15 [2.17.38.11] CARRRDYGDYGDGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagtgactactacatgacctggatccgccaggctccagggaaggGggctggagtgggtttcatacattcgtagtaatgggagtcccatatacaacgcagactctgggaggggccgattcactatctccagggacaacgccaagaactcactgtatctgcaaatgaatagtctgagagtcgaggacacggccgtgtattactgtgcgagacggcgggactacggtgactacggtgacggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 21903 JY8QFUQ01AVU2V productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + tccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccaggggcttcttccccca 21904 JY8QFUQ01BBGN6 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F or Homsap IGHV3-30*03 F or Homsap IGHV3-30*04 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*07 F or Homsap IGHV3-30*09 F or Homsap IGHV3-30*10 F or Homsap IGHV3-30*13 F or Homsap IGHV3-30*14 F 103 88.46 23/26 nt 7 X X 7.X.X [1.X.X.X] null + No rearrangement found cctctggattcaccttcggaacctat 21905 JY8QFUQ01AWJKB unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.26 166/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcCccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 21906 JY8QFUQ01BE00R unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 994 95.83 207/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDNYGDY## out-of-frame + tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggccttcttccccca 21907 JY8QFUQ01C21Q2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 919 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-16*02 F 3 8 8 X 8.8.X [2.17.38.11] CAKDGMMTFWGELSSPVG#FFDYW out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); gcctctggattcaGcatttggtgactatgtcatgagctgggtccgccaggctccagggaagggactggagtgggtctcaactattagtggtagcggtggaactacatattatgcagactccgtgaagggccggttcaccatttccagagacaactccaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgaaagatggaatgatgacgttttggggggagttatcgtccccagtaggttcttctttgactactggggccagggagccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21908 JY8QFUQ01ASVZA productive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-22*01 F 2 8 8 13 8.8.13 [1.17.38.11] CAKDGDSGWDYYDHW in-frame + cctctggatttaactttgatcaatatgccatgtattgggtccggcaagctccagggaagggcctggagtgggtctccggtatcactgggaatagtggttccataggctatgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaagtcactatatttggaaatgaatagtctgagtgttgaggacacggccttgtatttctgtgcaaaggatggcgacagcggttgggattattatgaccactggggcccgggaactctggtcaccgtctcgtcagcttccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21909 JY8QFUQ01B5K1V unproductive Homsap IGHV3-7*01 F 995 95.41 208/218 nt 93.58 204/218 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.16.38.11] CAISSGYYSTGY## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 41 of V-REGION: 1 nucleotides (from position 38 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 71 in the user submitted sequence), (cause frameshift) aggctctggattcagctttagttactattggatgagcgggtccgccaggctccagggaaTggggctggagtggtggccaacataaaggGaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgaaagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21910 JY8QFUQ01BWZW5 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 886 90.28 195/216 nt 89.81 194/216 nt Homsap IGHJ2*01 F (see comment) 85 62.26 33/53 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CVSDLAGQKG#LG out-of-frame - Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 88 of V-REGION: 'C' (1 nucleotides at position 166 to 166 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagctacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagctgCtttttgcaaatgaacagtctgagaggcgaggacacggctgtctattactgtgttagcgatttggctggtcagaaaggtttctgggggccaggggagtcctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21911 JY8QFUQ01B8AN9 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 954 93.55 203/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.16.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) cctctggattcaCcctttggttattatggcatgactgggtccgccaagctccggGggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21912 JY8QFUQ01CLEGR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-23*01 ORF 2 8 8 14 8.8.14 [1.17.38.11] CARAYSGPGPYYFDYW in-frame + cctccggattcaacttcaattactttagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtgatggtacttacatatactacgcagactcagtgaagggccgattcgccatctccagagacaacgccaaagactcactgtatctacaaatgaacatcctgagagccgaggacgcggctgtttattactgtgcgagagcctacagtggccctgggccttactactttgactattggggccagggaatcctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctgtccagggcttcttccccca 21913 JY8QFUQ01B3IKP productive (see comment) Homsap IGHV4-61*02 F 986 94.95 207/218 nt 93.58 204/218 nt Homsap IGHJ3*02 F 205 90.0 45/50 nt Homsap IGHD3-10*01 F 3 9 7 11 9.7.11 [1.17.38.11] CATVARRGAFDIW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'CTA' (3 nucleotides at position 25 to 27 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 35 of V-REGION: 3 nucleotides (from position 24 in the user submitted sequence), (do not cause frameshift) tctctggtgggtccatcagcagtaCTAgttactactggagctggatccggcagcccgccgggaagggactggagtggatggggcgtatctataccagtgggatcaccaactacaaccCcctccctcgagagtcgagtcaccttttcagtggacacgtccaagaaccagttctccctgaagctgaagtctgtgacccccgcagacacggccgtttattactgtgcgacagtggcgcgccggggggcttttgatatctggggccaagggacactggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21914 JY8QFUQ01A9619 productive Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 1013 98.56 206/209 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-17*01 F 2 6 8 16 6.8.16 [X.17.38.11] CARQLDYGDYSRHGLDVW in-frame + acaactttaccggctactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgataccagatacagcccgtccttccaaggccaggtcaccatctcagccgacaagtccatcagcaccgcctacctgcagtggagcagcctgaaggcctcggacaccgccgtgtattactgtgcgagacaattagactacggtgactactctaggcacggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtcagggcttcttccc 21915 JY8QFUQ01BNQPR productive Homsap IGHV3-7*01 F 990 95.39 207/217 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD2-15*01 F 3 8 8 11 8.8.11 [1.17.38.11] CAKGVVTATLTTG in-frame + ctctggattcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggtggtaacggcgaccttgactactggggccaggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgaccagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21916 JY8QFUQ01BVFZU productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1008 96.31 209/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtcgttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatacattagtaggagtagtactgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21917 JY8QFUQ01CZYWR productive Homsap IGHV3-9*01 F 888 89.55 197/220 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD3-22*01 F 2 8 8 26 8.8.26 [2.17.38.11] CVKDHGVTYFYDSVGYVSGAYNYAMDVW in-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cgtctctggattcacctttgatgattttggcatgcactgggtccggcaagttccagggaagggcccggagtgggtcgcaggtattagttggaatggtggacatatggactatgcggactctgtgaagggccgattcaccgtgtcccgagacaacgccgagaattccctgtatctgcaaatgaacagtctgacacctgaagacacggccctgtattactgtgtaaaagaccatggcgtcacttacttttatgacagtgttggttatgtctccggggcgtacaactacgcaatggacgtctggggccaggggacgacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21918 JY8QFUQ01BRCPZ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD3-22*01 F 3 7 8 X 7.8.X [2.17.38.11] CARGHSYYVSSGPDY## out-of-frame - in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 19 in the user submitted sequence), (cause frameshift) agcctctggattcaccttagcagctatgccatgaactgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggaagtggtgataccacatcgtacgcagactccgtgaagggccggttcaccatctcccgagacaattccaagaacacgatgtatctgcaaatgagtagcctgagagccgacgacacggccctttattactgtgcgagagggcacagttattatgtcagtagtgggcctgactactgggggccacggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21919 JY8QFUQ01BYIH9 No results 21920 JY8QFUQ01BXAQC unproductive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [2.17.38.11] CAFSRALTGEVDRLP*PL# out-of-frame - stop codons in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctccggattcacctttagtagttactggatgcactgggtccgccaaactccagGgggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcctttagtagagcactcacgggggaagtggatcgactaccttgaccactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 21921 JY8QFUQ01AC1K9 productive (see comment) Homsap IGHV3-48*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagGggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21922 JY8QFUQ01AV8QS unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 980 93.3 209/224 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt 8 7 X 8.7.X [4.17.38.11] CARRGPHFMI (see Functionality comment) out-of-frame + IMGT/JunctionAnalysis gives no results for this JUNCTION cctctgcagcctctggattcattgtcaatagcaactacatgagttgggtccgccaggctccagggaaggggctggactgcgtctcagttatttatcccggtggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagacggggtccccattttatgatagtgttaagggaaccctggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 21923 JY8QFUQ01CWHPI productive (see comment) Homsap IGHV4-59*03 F 935 93.02 200/215 nt 91.63 197/215 nt Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD3-22*01 F 2 8 7 16 8.7.16 [1.17.38.11] CARGHFDSSGYSNPLDHW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'GCGGGA' (6 nucleotides at position 92 to 97 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagTtttctactggagttggatgaggcagcccccagggaggggactggagtggattggatatgtccatggcaGCGGGAgtgggagcaccaactccaaccCcctccctcaagagtcgagtcaccatgtcagtggacacgtccaagaaccaattctccctgaagctgggctctgtgaccgctgcggacacggccgtgtattactgtgcgagaggacattttgatagtagtggttattccaaccctttagaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacacgcacccccagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21924 JY8QFUQ01BGTAF No results 21925 JY8QFUQ01C1ORV productive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [1.17.38.11] CARGDGVKDDYW in-frame + ctctggattcaccgtcaatagaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21926 JY8QFUQ01B023Y No results 21927 JY8QFUQ01CD1SU unproductive Homsap IGHV4-4*08 F, or Homsap IGHV4-59*01 F or Homsap IGHV4-59*07 F 782 85.12 183/215 nt Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD7-27*01 F 3 8 7 X 8.7.X [1.17.38.11] CASVRYLGERI#FDHW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) tctctggtggctccatgactggttactactggagttggatccggcagtccccagggaagggactggaatttgttggatctatctcttctgttggggacaccaactttgacccctccctcaggagtcgactcaccatgtccgtagacacgtccaagaaccagttttccctgaaagtgacctccgtgaccgcagcggacacggccgtctattactgtgcgagcgtgcgctatctcggcgaacgaatttttcgaccactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21928 JY8QFUQ01APW27 unproductive (see comment) Homsap IGHV1-18*01 F 939 93.46 200/214 nt 92.99 199/214 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 1 8 8 11 8.8.11 [0.17.38.11] CARVG*IGWYAYW in-frame + stop codons in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift); tggttacacctttaacacctatggttTtcagttgggtgcgacaggcccctggagaagggcttgagtggatgggatggatcagcggtcacaatggtaacacaaagtatgcacagaagttccaggacagagtcaccctgaccacagacacatccacgagcacagccttcatggaattgaggagcctgagatctgacgacacggccgtgtattactgtgcgagagtcgggtagattggctggtacgcctactggggccagggaaccctggtcaccgtcgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggctt 21929 JY8QFUQ01CKKV6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 914 91.28 199/218 nt Homsap IGHJ6*02 F (see comment) 247 88.71 55/62 nt Homsap IGHD2-2*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKTVVPAAPNR#YYYYGLDVW out-of-frame - Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctcaggattcacgtttagcaggtatgccatgaactgggtccgccaggctccagagaaggggctggagtgggtctccgctgttagtgatactggtggtacaacagagtacgccgactccgtgaaggggcggttcaccgtctccagagacaattccaagaatacggtgtatctgcaaatgaacagcctgagagtcgaggacacggccgtatattactgtgcgaagaccgtagtgccagctgctcctaatcgatttactactactacggtttggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21930 JY8QFUQ01CGLTX productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 967 92.44 208/225 nt 92.0 207/225 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD1-26*01 F 3 8 10 14 8.10.14 [2.17.38.11] CTRDLSGSYSGAFDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift); ggatctggattcacctttggtgactttgctatgagctggtttcgccaggctccagggaaggggctggagtggctaggtttcattagaagcaaaatttatggtgggacaccagaatacgccgcgtctgtgaaaggcagatgtcccatctcaagagatgattccAaaaaacatcgcctatctgcaaataaacggcctgaaaaccgaggacacagccatgtatttctgtaccagagatctcagtgggagctactccggtgcttttgatgtctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagcagatgggaacgtggtcatcgcctgcctcgtccaggctcttccccca 21931 JY8QFUQ01CA67J unknown (see comment) Homsap IGHV3-30*15 F 887 89.91 196/218 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 8 X 8.8.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. tctccggattcacctttagtaaatattccatgaactgggtccgccaggctccaggcaaggggctcgagtgggtggcacttatatcatacgatggaagtagaaaaatctacgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatctccaaatgagtagcctgagacctgaggacacggctgtctattactgtgcgaggaatgagctgccttgggatacaagagaatactacttttggactattgggggcccagggaaacccctgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21932 JY8QFUQ01BJL0D productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 820 86.3 189/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-21*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAKVGNLYFFEYW in-frame - gcctctggattcagcttcaacagctacagcatgaactgggtccgccaggctccagggaagggactggaatggatctcatcaattagtaccgctggcaccaccataggctacgcagactctgtgaagggccgattcactatttccagagacaacgccaagaactcagtatctctgcagatggacagcctgagagacgaggacacggcggtatattactgtgccaaagtgggtaatttgtatttctttgaatactggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21933 JY8QFUQ01A9AD7 unproductive Homsap IGHV1-69*01 F, or Homsap IGHV1-69*12 F or Homsap IGHV1-69*13 (F) or Homsap IGHV1-69D*01 F 930 92.99 199/214 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [0.17.38.11] CAKGSFDSSGRPEAFDI## out-of-frame + Other possibilities: Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tggaggcaccttcagtagatatgctttcagctgggtgcgacaggcccctggacaagggcttgagtggatgggagggatcgtccctctctttggttccataaagtacgcacagaagtaccagggcagagccacgattaccgcggacgaatccacgagcacagtctacatggagctgagcagcctgagatctgacgacacggccatgtattactgtgcgaagggttcctttgatagtagtggtcgccctgaggcttttgatatctggggccaagggtacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21934 JY8QFUQ01CF9AT No results 21935 JY8QFUQ01C812Q productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21936 JY8QFUQ01DCXVQ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 93.58 204/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD3-22*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKGDSGGYTHNYFDYW in-frame - cctctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggcctcacgtgttaatggtgatgggggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgcgacctgaggacacggccttntattactgtgcaaaaggggatagtggtggttatacccacaactactttgactactggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21937 JY8QFUQ01AN0AS No results 21938 JY8QFUQ01ACWF5 unproductive (see comment) Homsap IGHV3-33*04 F (see comment) 327 62.44 128/205 nt 60.0 123/205 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*02 F 25 64.29 9/14 nt Homsap IGHD5-12*01 F 2 5 8 65 5.8.65 [X.17.38.8] CAKYLFRCLRLTLDRTWGPGEPVAPPSPHAIQAKAHRSSPLGTLLQEXLWGAQRPWAAWSKDYFPEP in-frame + stop codons Low V-REGION identity (62,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 67 of V-REGION: 'GAGTAATAAATCACTAG' (17 nucleotides at position 98 to 114 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 77 of V-REGION: 'T' (1 nucleotides at position 141 to 141 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'GT' (2 nucleotides at position 147 to 148 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'CAAGG' (5 nucleotides at position 164 to 168 in the user submitted sequence), (cause frameshift); cagcctctggattcaccttcagtgactatcacatgtactggGgtccgccaggctcagggcaggggctggagtgggctggcagttatatcatatgatgGAGTAATAAATCACTAGtgtagactccgtgaagggccgattcaTccatcGTccaggagacaagttcCAAGGatgcgctggcttttgctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaagtacctcttcaggtgtctacgacttactttggaccgtacctgggggccaggggaacccgtggctccaccgtctcctcacgccatccaggccaaggcccatcggtcttccccccttggcaccctcctccaagagcncctctggggggcacagcggccctgggctgcctggtcgaaggactacttccccgaaccggtggacggtgtcgtggcaactcg 21939 JY8QFUQ01BOBY3 productive (see comment) Homsap IGHV4-4*02 F, or Homsap IGHV4-4*03 F or Homsap IGHV4-4*04 F or Homsap IGHV4-4*05 F 887 89.91 196/218 nt 89.45 195/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 9 7 12 9.7.12 [1.17.38.11] CAANLGHGSYFKYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 94 of V-REGION: 'T' (1 nucleotides at position 186 to 186 in the user submitted sequence), (cause frameshift); tctctggtgactccgtcagcagtgataactggtggagttgggtccgccagaccccagggaaggggctggagtggattggagaaatctatcatggtgggaccaccaactacaatccgtccctcaagggtcgagtcaccttatcggtcgacaagtccaagaaccaattctctctgagaatgacctctTtttaccgccgcagacacggccgtgtattactgtgcggccaatctgggtcatgggagttatttcaaatattggggcccgggaatcctggtcaacgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21940 JY8QFUQ01B7KYD No results 21941 JY8QFUQ01BEUNL productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame - ctctggattcaccttcagtagctactggatgcattgggtccgccaagctccagggaaggggctggagtgggtctcacgtattcatagtgatgggactaccacatactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaggaacacgttgtatctgcaattgaacagtctgagagccgaggacacggctgtgtattattgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21942 JY8QFUQ01AQKZO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21943 JY8QFUQ01B3VKV No results 21944 JY8QFUQ01AJUZ2 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 890 90.7 195/215 nt Homsap IGHJ4*01 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 1 8 8 X 8.8.X [0.17.38.11] CAKDLVVTSIGPQGIHGH## out-of-frame - ctgggttcacctttagcagctatgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaagtatcagttttagtggtgagagaacatattatgcagactccgtgaagggccggttcaccatctccagagacaactccaagaacacagtacatttgcaaatggacagcctgagagccgaggacacggccgtatattactgtgcgaaagatctggtggtgactagtattggcccccagggaatccatggccactgggggccgaggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21945 JY8QFUQ01C7N4Z unproductive Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1003 94.22 212/225 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-22*01 F 3 10 9 X 10.9.X [1.17.38.11] CARGGDYYDSGGLDY## out-of-frame - tccggggacagtgtctctagcagcagtgttgtttggaactggatcaggcagtccccattgagaggccttgagtggctgggaaggacattctacaggtccaggtggtataatgattattcattatctctgaaaagtcgaataaccatcaacccagacgcatccaagaaccagttgtccctgcagctgaagtctgtgactcccgaggacacggctgtatattactgtgcaagagggggtgattattatgatagtggtggtcttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21946 JY8QFUQ01BXEV0 unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 94.17 210/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.37.11] CTTGGWN*L##W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 162 in the user submitted sequence), (cause frameshift) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacaggggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21947 JY8QFUQ01A2GYI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt 92.66 202/218 nt Homsap IGHJ4*03 F (see comment) 105 68.75 33/48 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARPFSGRWCFDL## out-of-frame + Other possibilities: Homsap_IGHJ2*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagttactcctggatgcactGgggtccgccaagttccagggaaAGggggccggtgtgggtctcacaaattaaaagtgatgGggagtaccccaagttacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagtcgaggacacggctgtttattactgtgcaagaccgtttagtgggaggtggtgcttcgatctctgggggccgtggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagccctcgacagcaccccccaagatgggaacgtggtccgtcgcatgcctggtccaggggcttcttccccca 21948 JY8QFUQ01AVWB4 No results 21949 JY8QFUQ01DDC0C productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1009 95.89 210/219 nt 95.43 209/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVRSEYSSSNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 78 of V-REGION: 'C' (1 nucleotides at position 139 to 139 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcagtagctatagaatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattgatagtagtagtcacaacatatactacagagactcagtgaagggccgattcaccCatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagatccgagtatagcagttcaaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttccccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 21950 JY8QFUQ01BZKZW No results 21951 JY8QFUQ01CBSDR unproductive Homsap IGHV3-30*04 F, or Homsap IGHV3-30*14 F or Homsap IGHV3-30-3*03 F 1004 95.87 209/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-9*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKKGPNRITIFWSGHW#YYGMDVW out-of-frame + cctctggattcaccttcagtagctatgctatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatctgatggaagtaataaaaactatgcagactccgtgaagggccgattcaccatctccagagacaattccaacaacacactgtatctacacatgaacagcctgagagctgaggacacggctgtttattattgtgcgaagaaagggccaaaccgtatcacgattttttggagtggtcactgggtactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 21952 JY8QFUQ01B8FR6 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1026 97.24 211/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-12*01 F 1 8 8 11 8.8.11 [1.17.38.11] CVVQILGATIDYW in-frame + ctctggattcaccttcaatacctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtggtagtacttacataaagtacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtggtccagatcctaggggctacgattgactactggggccagggaacccgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21953 JY8QFUQ01AGUNF unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - ctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21954 JY8QFUQ01C85VB unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 986 94.95 207/218 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD5-12*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDLFQVSTTYF*LLG in-frame - stop codons Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttacttttgactactgggggcccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggncttcccccctggcaccctcctcccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21955 JY8QFUQ01C2FK7 unproductive (see comment) Homsap IGHV3-71*01 P 1106 99.55 223/224 nt 98.66 221/224 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD2-21*02 F 2 8 10 20 8.10.20 [1.17.38.11] CARIHPRLRGGGDCYYGWFDPW in-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgactactacatgagctgggtccgccaggctcccgggaaggGggctggagtgggtaggtttcatcagaaacaaagctaatggtgggacaacagaatagaccacgtctgtgaaaggcagattcacaatctcaagagatgattccaaaaTgcatcacctatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgaggatccatccccgcctacgtggcggtggtgactgctattatgggtggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttgccccgaaccggtgacggtgtcgtggaaactca 21956 JY8QFUQ01B1VYC No results 21957 JY8QFUQ01CMVKV productive (see comment) Homsap IGHV3-48*03 F 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaGggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagGactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21958 JY8QFUQ01AUPY6 No results 21959 JY8QFUQ01DJI2W productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 908 91.2 197/216 nt 89.81 194/216 nt Homsap IGHJ3*02 F 214 92.0 46/50 nt Homsap IGHD2-21*01 F 2 8 7 15 8.7.15 [2.17.38.11] CTRELRLAAARDGVDIW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'C' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcttctgggttcaccgtcagtagcaagGttcatgagctCgggtccgccaggctccagggaaTggggctggantgggtctcaattacttatcctgatggtactacatattatggagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactggatcttcaaatgaacagcctgagagccgaggacacggccgtttattattgtacgagagaacttaggctggctgctgcgcgtgatggtgttgacatctggggccaggggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21960 JY8QFUQ01B6U5G No results 21961 JY8QFUQ01CCWTD No results 21962 JY8QFUQ01AZUTN productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 981 94.93 206/217 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-9*01 F 2 8 8 18 8.8.18 [1.17.38.11] CVKVAGDYRTPNYGWHFDLW in-frame - ctctggattcacctttagcacctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagttattagtggtagtggtggcagcacattctactcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacactggatctgcaaatgaatagcctgagaggcgaagacacggccgcatattactgtgtgaaagtggccggtgactatagaactcccaactacggctggcacttcgatctctggggccgaggcaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21963 JY8QFUQ01B9C15 unproductive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 918 91.71 199/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*02 F 1 8 8 X 8.8.X [1.16.38.11] CVRAGFGGVIG#FDCW out-of-frame - stop codons in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 203 to 203 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 34 in the user submitted sequence), (cause frameshift) cctctggattcacctttggttattatggcatgactgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacgGgccttatatcactgtgtgagagcagggttcgggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21964 JY8QFUQ01B45A8 unproductive Homsap IGHV3-7*01 F 949 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD2-15*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDPRSVSRYSLFGLL# out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 103 of V-REGION: 'T' (1 nucleotides at position 212 to 212 in the user submitted sequence), (cause frameshift); tctggattcacctttagtgactattggatgagctgggtccgccaggctccagGggaaggggctagagtgggtggccaacataaatagagatggaagtgagcaacactatgtggactctgtgaagggccgattcaccatctccagagacgacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacatggctatgtatTttttgtgcgagagatcctcgttccgtgagcaggtactctttatttggactcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttct 21965 JY8QFUQ01CEGTD productive Homsap IGHV4-61*02 F 970 93.24 207/222 nt Homsap IGHJ6*02 F 247 88.71 55/62 nt Homsap IGHD3-16*02 F 1 10 7 17 10.7.17 [2.17.38.11] CARGKWGDKPPFYYGMDVW in-frame + gtctctggtggctccatcaggagtggtagttactactggagctggatccggcagcccgccgggaagggactggagtggattgggcgtatatatagcagtgggagcatcgacgccaacccctccctcaagagccgagtcaccatatcaattgacacgtccaagaaccaggtctccctgaaactgggctctgtgaccgccgcagacacggccgtctattattgtgcgagagggaagtggggggacaaaccgcccttctactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21966 JY8QFUQ01DWHZD No results 21967 JY8QFUQ01DUQPR productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 814 86.57 187/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*02 F 3 8 8 12 8.8.12 [1.17.38.11] CVKDISRSGCFEYW in-frame - tctggattccagtttagcaactatgccatgagctgggtccgtcaggctcctgggaaggggctggagtgggtctcaactattagtaaagacggtgtttacacctactaccccgactccgcgaagggccgggtcaccatctccagagacaattccaagaatacaatttatttgcaaatgaacagcctgacagccgaggacacggccagatattactgtgtgaaagacatttccaggtcaggctgctttgagtattggggtcagggaaccctgatcaacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 21968 JY8QFUQ01BDGHR productive (see comment) Homsap IGHV4-39*03 F 929 91.36 201/220 nt 90.45 199/220 nt Homsap IGHJ3*01 F 232 96.0 48/50 nt Homsap IGHD3-22*01 F 3 10 7 17 10.7.17 [1.17.38.11] CARSITLTVVVMNDAFDVW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctccggtggctccatcaacagtagAaaattattattggggctggatccgccagcCccccagggaagggtttggagtggattggaaatatctattatagtgggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctggggccaagggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 21969 JY8QFUQ01AZW95 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-10*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAIEHTLPSGQGLGIEYFW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'AC' (2 nucleotides at position 158 to 159 in the user submitted sequence), (cause frameshift); ctctggattcaactttaacagctttgccatgagctgggtccgccaggttccagggatggggctggagtgggtctcagccattagtggtagtggcgggagcacattctacgcagactccgtgAaagggccggttcaccatctccagagacaactccaaACaaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccttatattattgtgcgatcgagcatacccttccgtccggacagggattagggattgaatatttctggggccagggaaccctggtcatcgtcccctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 21970 JY8QFUQ01DHB91 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 8 12 8.8.12 [1.17.38.11] CVRGTREWSGIDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcattttcagtaactactggatgcactgggtccgccaagctccagggaaggGggctgctctgggtctcagtcattaatagtgacggcagtgaaattcactacgcggactccgtgaggggccgattcaccatctcccgagacaacgccaagaacacgctgtatttgcaaatggacaatctcagaggcgacgacacggctctatattattgtgtaagagggacaagggaatggagcgggattgactactggggtcagggaaccctggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21971 JY8QFUQ01B35E5 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-33*05 F (see comment) 739 82.19 180/219 nt 79.91 175/219 nt Homsap IGHJ4*02 F 78 62.5 30/48 nt Homsap IGHD5-12*01 F 2 8 8 X 8.8.X [2.16.38.11] CV*KDVDTMTTASTT## out-of-frame - stop codons Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'TC' (2 nucleotides at position 199 to 200 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 49 in the user submitted sequence), (cause frameshift) agcgtctggattctccttcaTgcaattatgccgatcactgggtccgccagctccaggcaaggggctggagtAgggtggcggAccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggataccctttcgggtTCgacgacacggctgtctattattgtgtttaaaaggacgtggatacaatgactacggcctcgactactgggggccccgggaaccctgctcaccgtctcctcagcctcccaccaaggggcccatcggtcttcccccctggcncccctccctccaagagcacctctggggggnacagcggccctgggntgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactag 21972 JY8QFUQ01DRVYG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 958 93.98 203/216 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame + tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggctttttccccca 21973 JY8QFUQ01A7IC1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 869 88.99 194/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [1.17.38.11] CARDGVRGVGAYYIYYFDLW in-frame + cctctggattcacctttggcctctatgccatgaactgggtccgccaaactccagggaaggggctggagtggctcgcaactattagtggtagtggaagtagatcattttacgcagactccctgaagggccggttcaccatctccagagacaattccaagggcacggtatacctggaaatgaccaccctgagagccgaggacacggccgtatattactgtgcgagagatggggtccgtggcgttggtgcttactacatctactattttgacttatggggccagggaaccctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21974 JY8QFUQ01AECMS productive Homsap IGHV3-66*02 F 948 93.93 201/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 12 8.7.12 [1.17.38.11] CVGDRQRDNYFAYW in-frame - ctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtgggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 21975 JY8QFUQ01BU3KK unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*02 F or Homsap IGHV3-13*05 F or Homsap IGHV3-30*05 F or Homsap IGHV3-30*13 F 108 53.33 72/135 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found ctctggattcaacctcaatacctttggcatgaactgggtccgccctgctccaggagcaccctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact 21976 JY8QFUQ01DPHLJ No results 21977 JY8QFUQ01A152Y unproductive Homsap IGHV3-48*01 F 1080 99.54 216/217 nt Homsap IGHJ6*02 F 256 90.32 56/62 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CASNFLEWFPWG#YYYGMDVW out-of-frame - ctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagtagtagtagtagtaccatatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgcgcctcgaattttttggagtggttcccctggggaactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21978 JY8QFUQ01BI65O unproductive Homsap IGHV4-61*02 F 786 99.38 159/160 nt 98.75 158/160 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-8*01 F 3 X 7 X X.7.X [X.8.38.11] CARGYCSNAVCYQIMN## out-of-frame - in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) ggaagggactggagtgattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagccaccatatcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtattactgtgcgagaggatattgttctaatgctgtatgctatcaaatcatgaactgggggccagggaaccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21979 JY8QFUQ01B957P productive (see comment) Homsap IGHV1-18*01 F 804 88.29 181/205 nt 87.32 179/205 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD1-20*01 F 1 5 8 11 5.8.11 [X.17.38.11] CARVIRTNWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 25 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); tggttacacctatggcgtcacctgGggtgcgacaggCcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatgataatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacggccgtatattattgtgcgcgagtaattcgaaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21980 JY8QFUQ01C1FLO productive (see comment) Homsap IGHV1-3*01 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-8*01 F 2 8 8 9 8.8.9 [0.17.38.11] CARWNNDLDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'C' (1 nucleotides at position 31 to 31 in the user submitted sequence), (cause frameshift); tggatacaccttcagtacctatactataaaCttgggtgcgccaggcccccggacaaaggcttgagtggatgggatggatcaacgctgaccttggcaacacaaaatattcacagaagttccagggcagactcaccattaccagggacacatccgcgaacacagcctacatggagctgagcagcctgacatctgaagacacggctgtgtattactgtgcgagatggaacaatgaccttgactattggggccagggaaccctagtcactgtctcttcagcatcccctgaccagccccaaggtcttcccgctgagcctcgacagcaccccccccgaagatgggaacgtggtcgtcgccatgcctggctccagggcttcttcccccca 21981 JY8QFUQ01BK8O3 productive (see comment) Homsap IGHV3-30*10 F (see comment) 752 83.03 181/218 nt 82.57 180/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 85 of V-REGION: 'G' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaagggccgattctccatctccagagacaattccaaaaaGtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 21982 JY8QFUQ01A886F unknown (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F 125 56.52 65/115 nt 8 10 X 8.10.X [1.17.2.X] null + No rearrangement found ctctggattcagctttagttactattggatgagctgggtccgccaggctcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21983 JY8QFUQ01CEADI unproductive Homsap IGHV3-33*05 F (see comment) 752 83.03 181/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CVKGRGYNDYGLDY## out-of-frame - Low V-REGION identity (83,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 62 of V-REGION: 'A' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cgtctggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatAttaatgaaaagatattatgcagagtccgtgagGgggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactgggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 21984 JY8QFUQ01B1GGR No results 21985 JY8QFUQ01ASULW productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - tcaggattcaccttcagtaggtactggatgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccctccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21986 JY8QFUQ01BA8HI unproductive Homsap IGHV3-48*02 F 895 90.74 196/216 nt 88.89 192/216 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CARGQKMATKCF#WFDSW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 41 of V-REGION: 'AG' (2 nucleotides at position 35 to 36 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 116 to 116 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 101 of V-REGION: 'T' (1 nucleotides at position 209 to 209 in the user submitted sequence), (cause frameshift); tctggattcaccttcgacagatacagtatgaactAGgggtccgccaggctccagggaggggactggagtgggAtttcatacataagtactactactagtaacagatactacgcagCacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctTgtatattattgtgcgagaggtcaaaaaatggctacaaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctggggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21987 JY8QFUQ01A1WNI unproductive Homsap IGHV3-30*10 F (see comment) 725 81.65 178/218 nt 81.19 177/218 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [2.17.37.11] CLAEVGGRQFDN## out-of-frame - Low V-REGION identity (81,65% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT, from codon 72 of V-REGION: 1 nucleotides (from position 124 in the user submitted sequence), (cause frameshift) acctctggattcaccttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggcgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactgggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 21988 JY8QFUQ01CFYEV unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F (see comment) 723 82.24 176/214 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [1.17.38.11] CARDWGGSFDRYYFDY## out-of-frame - Low V-REGION identity (82,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ccaccgtgggtctttcactggttatcgctggagctggatccgccaggccccagggaagggactggagtgggtgggggacatcaactttaaaggaagcaccaattacaacccgtccctgaagagtcgactcaccatattagcagacttgtccaggaatcggttctctctagacctaagtggtgtgaccgccgcggacacggctatgtattattgtgcgagagattggggtggaagcttcgataggtattattttgactactgggggccagggaatcctggtcactgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 21989 JY8QFUQ01DJU2K productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 800 86.05 185/215 nt 84.65 182/215 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD3-10*01 F 1 8 7 13 8.7.13 [1.17.38.11] CATVRHLGERIFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); tctctgggggcCaccatgagtagtttctactggagctgggttcggcagTcccccagggaggggactggagtggattggatttgtttcttacagtgGggcccaccaactacagcccctccctcaagagtcgagtcaacttatcactggacgcggccaacaaacagttctctttgcagctgcgttctgtgaccgctgcggacacggccatttattactgtgcgacagtacgacatctcggggaacgaatattcgatttctggggccagggtatcctggtcaccgtccccctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccctggtccagggcttcttcccccc 21990 JY8QFUQ01CCN49 productive (see comment) Homsap IGHV3-23*03 F (see comment) 855 88.48 192/217 nt 87.56 190/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-21*02 F 3 8 7 12 8.7.12 [2.17.38.11] CARQTAPFGYFEDW in-frame + Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CCN49 ; 8 AA in Homsap_IGHV3-23*03) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); aggctctggattcacgtttggcatctatgccatgagttgggtccgccaggctccagggaaGggggctggagtgggtctcagttatttatagcggtggtagtgcatattatgcagactccgtgaGggggccgattcaccatcgccagagacaaatctaagaacgtgttgtatcttcaaatgaacagtctgagacctgaggacacggctgtgtactactgtgcgagacagactgccccttttgggtactttgaggactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 21991 JY8QFUQ01A0SY0 No results 21992 JY8QFUQ01CCZV6 productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 957 94.39 202/214 nt 93.93 201/214 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 201 88.24 45/51 nt Homsap IGHD1-26*01 F 1 8 7 18 8.7.18 [1.17.38.11] CARGWAQQAGATFVGWFDSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift); ctatggtgggtccttcagtggttacacctggaactggatccgccagcCccccagggaaggggctggagtggattggggaaatcaatcatagtggcaggaccaactacaacccgtccctcaagagtcgagtcaccatatcaatagacacgaccaacaaccagttctccctgaagttgacctctgtgaccgccgcggacacggctgtatatttctgtgcgagaggttgggcccaacaagcgggagctacgtttgttggctggttcgactcctggggccaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 21993 JY8QFUQ01AJQBH No results 21994 JY8QFUQ01A8NO3 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame - ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccagttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21995 JY8QFUQ01DNXJJ unproductive (see comment) Homsap IGHV3-66*02 F 953 93.95 202/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-20*01 F 3 8 7 X 8.7.X [1.17.38.11] CVGRSSKG*LFR#YW out-of-frame + stop codons cctctggaatcagcgtcgggagcaactacatgaactgggtccgccaggctccggggaaggggctggagtgggtctcagttatttataccgggggtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacaccctttatcttcaaatgaacagcctgagagctgaggacacggctgtgtacttctgtgtggggagatcgtcaaagggataactatttcgcatactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 21996 JY8QFUQ01APYLJ productive (see comment) Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 55 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataGccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 21997 JY8QFUQ01A20SX No results 21998 JY8QFUQ01A2ZKE productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 842 87.61 191/218 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + cctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgaaagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggctgtcgtggaact 21999 JY8QFUQ01BZ3QS productive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F 836 87.91 189/215 nt 86.98 187/215 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD3-16*01 F 3 8 7 14 8.7.14 [2.16.38.11] CARKGLVPSMFFFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 10 to 10 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 60 in the user submitted sequence), (cause frameshift) gtctctggtGgggtccttcagtggttacttctggaactggatccgccagcccccagggaagggccggagtggattggagaagtcagtcatgatggaagtaccaacttcaatccgtccctcaagagtcgagtctccatgtcagttgacacgatcaagaagcaggtcttcctgaaactgagctctgtgactgccggggacacggctatatattattgtgcgagaaagggacttgtgccatctatgttcttctttgacttctggggccagggatccctggtcaccgtgctcctcagcctccacaaggccatcggtcttgccccctggcaccctctccaagagcacctctgggggcacagcggccctggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22000 JY8QFUQ01CCTZY productive Homsap IGHV3-7*01 F 887 89.91 196/218 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARDPSYSYYNGLDVW in-frame + cctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaagggactggagtgggtggccagtataaagcaggatgggggggagacatattatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagaagtcactgtatctgcaaatgaacagcctgggagtcgaagacacggctgtttattactgtgcgagagatccatcttactcctactacaatggtttggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22001 JY8QFUQ01AJU3I unproductive Homsap IGHV4-30-2*02 F 308 95.59 65/68 nt Homsap IGHJ3*02 F (see comment) 133 74.0 37/50 nt Homsap IGHD3-22*01 F 3 X X X X.X.X [X.X.22.11] CARLKLSNGYYFDY## out-of-frame - Other possibilities: Homsap_IGHJ5*01 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) ggtccaagagccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattattgtgcgagattgaaattatctaatggttactactttgactactgggggccaaggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22002 JY8QFUQ01B24EY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 941 92.66 202/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcacctttaccGaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgCaggggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22003 JY8QFUQ01AZ15O productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 896 90.37 197/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD1-26*01 F 1 8 8 15 8.8.15 [1.17.38.11] CAKDQSCIVGPCGFDYW in-frame + cctctggattcaccctcaggacctatagcgtgaactgggtccgccaggctccagggaaggggctggagtgggtctcggctattagtggaagtggtgcaaccacatactacgcagactccgtgaagggccggttcgccatctccagagacaattccaagaacacgctatatctacaaatgaacaacctaggggccgaggacacggccgtttattactgtgcgaaagatcagtcctgtatagtgggaccttgtggttttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22004 JY8QFUQ01A18LF unproductive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 955 93.15 204/219 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [2.17.38.11] CARDRRGYSYEMDY## out-of-frame + acctctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactgggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22005 JY8QFUQ01CQ1Y4 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 968 94.04 205/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame + cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22006 JY8QFUQ01AXNWU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F (see comment) 222 95.83 46/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAKDKWYYDSSGYQYYLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'A' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); gcctctggattcCccctttagcaactGatgacatgaAattgggtccgccaggctccagggaaggggctggagtgggtctccggtattagtggtagtggcggtagcacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctggatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagacaaatggtactatgatagtagtggttatcaatactaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22007 JY8QFUQ01B1VT1 productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1002 94.62 211/223 nt 93.72 209/223 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 9 8.10.9 [1.17.38.11] CTTGGGTNYYW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 161 to 161 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 89 of V-REGION: 'A' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaAaaaaatatgctgtatctAgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacagggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 22008 JY8QFUQ01A0AX9 No results 22009 JY8QFUQ01CJNT4 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 969 93.64 206/220 nt 93.18 205/220 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 3 8 8 11 8.8.11 [2.17.38.11] CVRDRSGQAVGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); agcctctggattcaGccttcagtagttactggatgcactgggtccgccaagttccagggaagggactggtgtgggtctcacgaattaatactgatgggagtgccacaagttacgcggactccgtgaggggccgattcaccatctccagagacaacgccaagaacacgctatatcttcaaatgaacagtctgagagtcgaagacacggctgtctattactgtgtaagagatcggtccggtcaggcggtaggatactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22010 JY8QFUQ01B3A8Z productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 143 to 143 in the user submitted sequence), (cause frameshift); ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccCagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22011 JY8QFUQ01CSWJJ productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F (see comment) 768 82.96 185/223 nt Homsap IGHJ3*01 F (see comment) 187 86.0 43/50 nt Homsap IGHD3-9*01 F 2 8 10 13 8.10.13 [1.17.38.11] CATDSPTGYYAFDVW in-frame + Low V-REGION identity (82,96% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) ctctgggttcgttttcagtgatgcctggatgagttgggtccgccaggctccaggcaaggggctggagtggattggtcgtatcaagaacaaagctgacggagaggcaacagattacgccgcgcccgtgaaaggcagattcgtcatctcaagggatgactcgaaaaacatggtgtatctgcaattgaaccgcctaagagccgaggacggaggcttgtacttctgtgccacggattcccctactggatattatgcttttgatgtgtggggccgagggactcgggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22012 JY8QFUQ01CB27C productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 985 95.37 206/216 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - tctggattcaccttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtgttaatggtgatggaggtagcacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggctgtatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22013 JY8QFUQ01AUJPZ productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 837 87.56 190/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARDSASSGYARYDAMDVW in-frame + ctctggattcagttttagtacacatggcatgaactgggtccgccaggctccagggaaggggccggaatgggtctcattcgttaatagtggaagtagttacatctactacgcagactcagtgaggggccgattcaccatctccagagacgacgccaggaattcactgtatctgcaaatgcaccgcctgcgagtcgaggacacggctctctactattgtgcgagagacagtgcctcgtccggctacgctaggtacgacgctatggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 22014 JY8QFUQ01CGB39 unproductive (see comment) Homsap IGHV3-30*17 F 981 94.93 206/217 nt 94.47 205/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 X 8.8.X [1.17.38.11] CAGRFNWGSVLL*Q*WFK#YW out-of-frame - stop codons in FR2-IMGT at codon 46 of V-REGION: 'A' (1 nucleotides at position 52 to 52 in the user submitted sequence), (cause frameshift); ctctagattcaccttcagtagctataatatgcactgggtccgccaggctccAgggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagctgaggacacggctgtgtattactgtgcggggagatttaactggggttccgtattattatgacagtagtggtttaaagtactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22015 JY8QFUQ01BHGAO productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 974 93.67 207/221 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD2-15*01 F 2 8 8 17 8.8.17 [2.17.38.11] CARPGGIAYCSGGSCYDPW in-frame - ggcctcctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtgcaagaccaggggggattgcctattgtagtggtggtagctgctacgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22016 JY8QFUQ01B6CFI productive (see comment) Homsap IGHV3-9*01 F 873 89.4 194/217 nt 88.94 193/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVKDRKGSNWYYFENW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift); ctctggattcaggtttgatgattatgccatgcactgggtccggcaagcGtccagggaagggcctggagtgggtctcaagtatcagctggggtggtgctagtatcctctatgcggactccgtgaagggccgattcaccatctccagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22017 JY8QFUQ01C06AD No results 22018 JY8QFUQ01BNCIH unknown (see comment) Homsap IGHV1-2*02 F 822 87.38 187/214 nt 86.92 186/214 nt 8 8 X 8.8.X [0.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 37 of V-REGION: 'A' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift); tggatacatattcaccgacAttttatatacactgggtacgacaggcccctggacaagggcttgagtggatgggatccatcaatcccaacagtggtgtcacaacctacgaagagaagtttcggggcagggtcaccatgaccagggacacgtccatcactacagcctacatggaactgacaagccttacatcagacgacacggccgtatattactgtgcgaaacatcctcttcgatcaacaagtggacattcctacttagattcctgggggccagggaacccctggtcacagtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 22019 JY8QFUQ01C0BEM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 571 88.89 128/144 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 X 8 16 X.8.16 [X.2.38.11] CAKEQRGSGWSRSALDVW in-frame - tcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaagggcccatcgtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22020 JY8QFUQ01CI1Z5 No results 22021 JY8QFUQ01A5TCV productive Homsap IGHV3-48*01 F 945 93.09 202/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 8 8 12 8.8.12 [1.17.38.11] CARDTGQWKDFDYW in-frame + ctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagtctgagagccgaggacacggctgtttattactgtgcaagagatacggggcagtggaaggactttgactactggggccagggaaccctggtcaccgtctccttagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 22022 JY8QFUQ01A6ZD5 productive (see comment) Homsap IGHV3-7*01 F 999 95.85 208/217 nt 95.39 207/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 7 8 11 7.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 30 of V-REGION: 1 nucleotides (from position 17 in the user submitted sequence), (cause frameshift) gctctggattcagcttagttactattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagagctcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22023 JY8QFUQ01B1LIV productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 1040 97.71 213/218 nt Homsap IGHJ3*02 F 88 64.0 32/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [1.17.38.11] CARPYCGGDCHNRGAFDIW in-frame + cgtctggattcaccttcagtagctatggcatacactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatggtatgatggaagtgaaatatactatgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 22024 JY8QFUQ01C5ZII unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 851 88.07 192/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD6-25*01 F 2 8 8 X 8.8.X [1.17.38.11] CASFRILESGY## out-of-frame + tctctggattcacattcggtagttttatgatgaactgggtccgccaggctccagggaagggactggagtgggtcgcatcgattagccctactagtactttcatagactacgcagactcagtgaggggccggttcaccatctccagagataacgccgagaacttactgtatctgcaaatgaacggcctgagagtcgaagacacggctgtctattactgtgcgagttttcgtatcctggaaagtggctactgggggccagggaaccttggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22025 JY8QFUQ01C7H7S unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F or Homsap IGHV3-69-1*01 P or Homsap IGHV3-69-1*02 P 98 52.63 70/133 nt 8 7 X 8.7.X [1.17.11.X] null - No rearrangement found stop codons tcctgattcatcttcagtgactactacatgacctggatccgccaggctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22026 JY8QFUQ01CXEH2 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 891 90.32 196/217 nt 88.94 193/217 nt Homsap IGHJ2*01 F 220 90.57 48/53 nt Homsap IGHD2-21*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKNRGVGDG##WYFDFW out-of-frame - stop codons in CDR2-IMGT at codon 57 of V-REGION: 'CTA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'A' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'G' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); ctctggattcgactttagcggctttgccatgagctgggtccgccaggccccagggaaggggctggagtgggtctcaactattaCTAatggtggtggtggtgtcgtactctacgcagactccgtgaAagggccgattcaccatctccagagacaatgccaagaacacactgtatctgcagatgaacagcctgcgagccgaggacacggccgtttaGtttctgtgcgaaaaataggggggtcggcgatggctgactggtacttcgatttctggggccgcggcaacctggtcactgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22027 JY8QFUQ01AEWVB productive (see comment) Homsap IGHV1-46*01 F, or Homsap IGHV1-46*03 F 885 90.65 194/214 nt 90.19 193/214 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [0.17.38.11] CARELGGSGTCGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacaccttcaccaggcactatatgcactgggtgcgacaggCcccctggacaaggacttgagtacatgggagtaatcaaccctagtggtggcgacacaagctacgcacagaggttccggggcagagtcgccgtgaccagagacacgtccacgagcacagtctatatggacttgagcagcctgagacctgaggacacggccatgtattattgtgcgagagagttgggaggttcggggacttgcggctttgactactggggccagggaagcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 22028 JY8QFUQ01APIZE unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F or Homsap IGHV3-15*05 F or Homsap IGHV3-15*06 F or Homsap IGHV3-21*01 F or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-30*01 F 106 95.65 22/23 nt 6 X X 6.X.X [1.X.X.X] null + No rearrangement found cctctggattcactttcagtagc 22029 JY8QFUQ01BOAH5 unproductive Homsap IGHV3-9*01 F (see comment) 771 83.64 184/220 nt 81.82 180/220 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-10*02 F 1 8 8 X 8.8.X [2.17.38.11] CVKGHGRGVRDSCH#FDHW out-of-frame + Low V-REGION identity (83,64% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'C' (1 nucleotides at position 67 to 67 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 68 of V-REGION: 'G' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'GC' (2 nucleotides at position 133 to 134 in the user submitted sequence), (cause frameshift); agcctctggattcGactttaagggaatatgccatacactgggtccggcaagttccaggaaaggggcCtggagtgggtcgcgggcatcaactggaatcggggcaaagcattgtatGggggactctgtgaggggGCccgattcaccatctccagagacaacgcccagaactccgtgtctctgcaaatgaacagtctgaggcctgacgacacggccttgtatatctgtgtaaaaggacatggtcgcggggtcagggactcttgtcacggtttgaccactggggccagggagtcctggtcaccgtctctccagcctcctaccaaggggcccctatcggtcttcccccctggcaccctcctccaagcagcacctctggggggccacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 22030 JY8QFUQ01CZX40 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGG## out-of-frame + cctctggattcacttttagcagccatatgatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtggggggggaccagggagccctggtctccgtctcctcagcatcccccgaccaggcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 22031 JY8QFUQ01ARUGW unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1019 95.93 212/221 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD4-17*01 F 3 10 7 X 10.7.X [1.17.38.11] CAWGVVRVELL*LL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctggtggctccatcagcagtactagttactactggggctggatccgccagcccccagggaaggggctggagtggattggtaacattcattctagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtatattactgtgcatggggggtggttcgggttgaactactttgactactgggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22032 JY8QFUQ01BS3SW productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 8 11 8.8.11 [2.17.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'GA' (2 nucleotides at position 85 to 86 in the user submitted sequence), (cause frameshift); gcctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaaggggctgtgtgggtctcacgcattGAaaaagtgatgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacatatttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22033 JY8QFUQ01DKMNN productive (see comment) Homsap IGHV3-7*01 F 900 90.78 197/217 nt 90.32 196/217 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-19*01 F 1 8 8 10 8.8.10 [1.17.38.11] CAGGRGWLIDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 77 of V-REGION: 'A' (1 nucleotides at position 134 to 134 in the user submitted sequence), (cause frameshift); ctctggtttcagcttaagtgactattggatgaactgggtccgccaggctccagggaaggggctcgagtgggtggccatcataaagaaagatggaagtgaagaactctatttggactctgtgaagggccgattcAaccgtctccagagacaacgccaagaactcactgtatctggaaatgaacagcctgagccccgaggacacggctgtatatttctgtgcggggggcagaggctggcttattgactactggggcctgggaaccgcggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22034 JY8QFUQ01DKSY4 productive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 981 94.93 206/217 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [1.17.38.11] CAKDLFQVSTTYFDYW in-frame - ctctggattcaccttcagtgactatcacatgtactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatatcatatgatggaagtaataaatactatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22035 JY8QFUQ01CK2OL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22036 JY8QFUQ01CGLGT productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 883 89.5 196/219 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD6-19*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKSPLSVAGTRQNWFDPW in-frame + ggctctgacttcacctttaatagctatgccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcggctattggtgccagtggctacagcacatactacgcagactccgtcaagggccgcttcaccatctccagagaccattccaacagcacgctgcatctgcaaatgaacagcctgagagccgaagacacggccgtttattactgtgcgaaatcccctctatcagtggctggtacacgccaaaactggttcgacccctggggccagggaaccctggtcaccgtttcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgc 22037 JY8QFUQ01A3DME productive (see comment) Homsap IGHV3-11*01 F 934 93.43 199/213 nt 92.49 197/213 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD2-15*01 F 2 8 7 18 8.7.18 [1.17.38.11] CARDGPPYLYGSHGNSFDQW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 63 of V-REGION: 3 nucleotides (from position 94 in the user submitted sequence), (do not cause frameshift) tctggattcagcttcagtgactactacatgagttgggtccgccaggctccagGggaagggactggagtgggtttcatgcatcactactagtggtaccacattctacacggactctgtgaggggccgattcaccatgtccagggacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggccgtgtattactgtgcgagagatggcccaccttatttatatggaagtcatggtaattcctttgaccagtggggccagggaaccctagtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22038 JY8QFUQ01CGBK8 unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 388 63.93 140/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found Low V-REGION identity (63,93% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggggctggaatgggtggccaacataaagcaacatggaggtgaaacgtactatgcggactctgtgaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22039 JY8QFUQ01BKFT5 No results 22040 JY8QFUQ01DLZC6 No results 22041 JY8QFUQ01A03E3 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 877 89.81 194/216 nt 89.35 193/216 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD3-9*01 F 2 8 8 10 8.8.10 [1.17.38.11] CVSDLAGQKGSW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); tcaggattcaccttcagtaggtactggaGtgcactgggtccgccaagttccagggaaggggccggtgtgggtctcacgtattaatgaagacggcagccacacagatcacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaagttgtatttgcaaatgaacagtctgagaggcgaggacacggctgtctattattgtgtaagcgatttggctggtcagaaaggttcgtggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgtctggtccagggcttcttccccca 22042 JY8QFUQ01AI9LC productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-7*01 F 3 8 8 13 8.8.13 [1.17.38.11] CATGAGNWNYIFNYW in-frame + ctctggatccaccgtcagtacctatagcctgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtggtttttatatatactacgcggactcagtgaagggccgagtcaccatctccagagacaacgccaagaactcgctatttctgcaaatgaacaacctgcgagccgaggacacggctgtctattactgtgcgacaggggccggaaactggaattacatttttaactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22043 JY8QFUQ01CCMPT No results 22044 JY8QFUQ01AQ6H1 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-21*02 F 3 8 8 16 8.8.16 [1.17.38.11] CAKDRYPRSTAITAPDYW in-frame - cctctggattcccctttagcaactatgccatgacctgggtccgccaggctccaggggagggactggaatgggtctcaagtattagaggtagtggtgacaggacatcctacgcagactccgtgaggggccggttcaccatctccagagacaattccaagaacacggtgtatctgcagctgaacaacctgagagccgaggacagggccgaatattactgtgcgaaagatcgctaccctcggtcgacagctattacagcgcctgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22045 JY8QFUQ01ASSCH productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt 93.55 203/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.17.38.11] CITSFGGRSLAYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 68 of V-REGION: 'GGAAA' (5 nucleotides at position 112 to 116 in the user submitted sequence), (cause frameshift); ctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcGGAAAaaactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtattacttcttttggtggaagatccctggcgtactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 22046 JY8QFUQ01DWXM5 No results 22047 JY8QFUQ01BEES7 productive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1035 95.58 216/226 nt 95.13 215/226 nt Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD3-10*02 F 1 10 9 13 10.9.13 [1.17.38.11] CTREGTLLRTVWTSG in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 80 of V-REGION: 'C' (1 nucleotides at position 152 to 152 in the user submitted sequence), (cause frameshift); tccgggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaacCccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggccgtctattactgtacgagagaggggaccctactacgtacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 22048 JY8QFUQ01B1HK3 No results 22049 JY8QFUQ01AK9IE unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 679 91.36 148/162 nt 90.74 147/162 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD5-18*01 F 1 X 7 X X.7.X [X.9.38.11] CARSKSGYSYGDFLH## out-of-frame - in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift); gggagggggctggagtggattgggagcatctattatagtgggagcatctcttacaaccCcgtccctcaggagtcgaatcaccatgtccgtggacatgtccaagaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctatttatttctgtgcgcggtccaagagtggatacagctatggtgacttcttacactgggggccagggaaccctggtcaccgtctccctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22050 JY8QFUQ01BT201 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 851 88.07 192/218 nt Homsap IGHJ5*02 F (see comment) 111 68.63 35/51 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CIMDLVGRADY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattgggggccagggaaccctggtcaccgtctcctcagcatcccctgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22051 JY8QFUQ01C54J3 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1019 95.93 212/221 nt 93.21 206/221 nt Homsap IGHJ3*02 F (see comment) 124 72.0 36/50 nt Homsap IGHD4-11*01 ORF 3 10 7 X 10.7.X [1.17.38.11] CARLDYTRYFDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'T' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'GG' (2 nucleotides at position 38 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 74 to 75 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 89 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 92 of V-REGION: 'C' (1 nucleotides at position 191 to 191 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagTttactactGGggggctggatccgccagcccccCAggggaaggggGCtgggagtggattgGggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgCacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtactttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22052 JY8QFUQ01AMTG3 productive (see comment) Homsap IGHV3-48*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDRGGSAYPIFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcaccttcggcagttataggatgagctgggtccgccaggctccagggaaggggctggagtggAttttcatacattagtagtagtagtagtgccatctattacgcagactctgtgaagggccgattcaccatctccagagacaatgccaagaactcagtgtatctgcaaatgaacagcctgagagacgaggacacggctatatattactgtgcgaaagataggggcggtagtgcttatcccatctttgactactggggccagggatccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 22053 JY8QFUQ01DL2G9 unproductive Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 814 86.57 187/216 nt 84.72 183/216 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD6-19*01 F 2 8 7 X 8.7.X [2.17.38.11] CVGSRSGIFSL#FQYW out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 33 to 33 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'ATG' (3 nucleotides at position 61 to 63 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 82 to 82 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 171 to 171 in the user submitted sequence), (cause frameshift); gcctctggattcactgtcaataacaactacatGgggttgggtccgccaggctccaggggaATGggggctggagtgggtctcGactactttattacggtggcaccacatattacgcagactccgcgaagggccgattcaccatctccagagacacctccaggaacacacttTtttcttcagatgaacagcctgagaagcgacgacacggctctatattattgtgttgggagtcggagtgggatcttcagtctccttccaatactggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22054 JY8QFUQ01CGEBO No results 22055 JY8QFUQ01BQT5H No results 22056 JY8QFUQ01CE87O productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30*14 F or Homsap IGHV3-30*18 F or Homsap IGHV3-30-3*03 F or Homsap IGHV3-30-5*01 F 955 93.15 204/219 nt 92.24 202/219 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD5-24*01 ORF 3 8 8 18 8.8.18 [2.17.38.11] CARKGPRRDGSLQQCDMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); gcctctggattcatcttcagcaaccttgcgatgcactgggtccgccaggctccaggcaaGggggctggagtGgggtggcaattatatcatatgatggaggtattaagtactatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctacaaatgaacaacctgagacttgaggacacggctgtgtattactgtgcgagaaaaggccccagaagagatggctccctacagcaatgcgatatggacgtctggggccaagggaccacgatcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccagga 22057 JY8QFUQ01B71RD unproductive Homsap IGHV3-7*01 F 841 87.56 190/217 nt 86.64 188/217 nt Homsap IGHJ1*01 F 134 73.08 38/52 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CVRDRPGGWALDY## out-of-frame - in FR2-IMGT at codon 48 of V-REGION: 'TG' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 77 to 77 in the user submitted sequence), (cause frameshift); ctctggattcagttttagtgacttttggatgcactgggtccgccaggcnccagggaaTGggggctggagtgggtggGcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggcctgagagccgaggacacggctctttattggtgtgtgagagatcgtccgggtggctgggcccttgattactgggggccagggcaccctggccgccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22058 JY8QFUQ01DWWKT No results 22059 JY8QFUQ01DW0DI productive Homsap IGHV4-4*07 F 813 86.92 186/214 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARQRGGGDRQWAFENW in-frame - ctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22060 JY8QFUQ01A5LEP No results 22061 JY8QFUQ01AX7FM No results 22062 JY8QFUQ01DI2O4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.61 205/219 nt 93.15 204/219 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD4-17*01 F 1 8 8 X 8.8.X [2.17.38.11] CARFGPLTRPDYW# out-of-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgCaggggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccaggggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22063 JY8QFUQ01DQPV4 No results 22064 JY8QFUQ01AMIZK productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'CCCAAT' (6 nucleotides at position 84 to 89 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcaacCCCAATcctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22065 JY8QFUQ01AHWBC No results 22066 JY8QFUQ01AGP4K productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 792 85.25 185/217 nt 84.33 183/217 nt Homsap IGHJ1*01 F 143 75.0 39/52 nt Homsap IGHD6-13*01 F 1 8 8 17 8.8.17 [1.17.38.11] CARPDGGNGWSFKNTSQMW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GGG' (3 nucleotides at position 60 to 62 in the user submitted sequence), (do not cause frameshift); ctctggattctcctttaatagttatgGgcatgagttggttccgccaggctccgggggaaGGGgggctggagtgggtctcatctattaccggcatgggtaatgacgcatactacgcagactccgtgcagggccggttcaccgtctccagagacaatcccgggaacaccctgtttctgcgaatggacagcctgagaatcgaggacacggccgtatattactgtgcgagacctgacggaggcaacggctggtcctttaaaaatacttcccagatgtggggccagggcacccttgtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22067 JY8QFUQ01B0UCM unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 401 77.21 105/136 nt 76.47 104/136 nt 8 6 X 8.6.X [1.17.12.X] null - No rearrangement found Low V-REGION identity (77,21% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 63 of V-REGION: 5 nucleotides (from position 98 in the user submitted sequence), (cause frameshift) cctctggattcatttttagcaattatgccatgaactgggtccgccaggctccagggaaggggccggagtgggtctcagcttttagtggtggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22068 JY8QFUQ01AMTHS productive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccctgaaccggtgacggtgtcgtggaactca 22069 JY8QFUQ01CLXP0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 957 92.38 206/223 nt 90.58 202/223 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD3-10*01 F 2 10 7 13 10.7.13 [2.17.38.11] CARRGSYGSGSYYPW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 36 of V-REGION: 'A' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'G' (1 nucleotides at position 93 to 93 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'T' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); tgtctctggtggcgccatcagcagtaatAgtttactactgggactggatccgccagcccccagggaagGgggctggagtggattgggagtatGtttttatactgggggTcaccttctacaacccgtccctcaagagtcgagttaacatttccgtggacacgtccaagagccagttctccctgaggctgagctctgtgaccgccgcagacacggctgtgtatcactgtgcgagacgtggttcctatggttcggggagttattatccctggggccggggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgttgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22070 JY8QFUQ01C633P productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 913 91.67 198/216 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 21 8.8.21 [1.17.38.11] CVRVGAPYYDFWSGYQTNWFDPW in-frame - tctggattcagcatcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtgcaagtactacttccatacattatgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttccctgtatttgcaaatgaacagcctgagagccgaggacacggctgtatattactgtgtaagagtgggggcgccatattacgatttctggagtggctatcagactaactggttcgacccctggggccagggaactctggtcaccgttacctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22071 JY8QFUQ01BUVZ9 No results 22072 JY8QFUQ01B0I72 productive (see comment) Homsap IGHV4-61*02 F 968 94.04 205/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 10 7 25 10.7.25 [1.16.38.11] CAREYPSDRDSSDSSGYLPTSGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 54 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 54 of V-REGION: 1 nucleotides (from position 80 in the user submitted sequence), (cause frameshift) ctctggtggctccatcagcagaggtaattactactggacgtggatccggcagccgccgggacgggactggagtggattggcgtatctatcccagtgggagaaccaactacagcccctccctcaagagtcgcgtcaccatatcagcagacacgtccaagaaccagttctccctgaagttgacctctgtgaccgccgcagacacggccttgtattactgtgcgagagagtacccctcggacagagattcctctgatagtagtggttatcttcccacctccgggccccttgactactggggcctgggaatccgggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22073 JY8QFUQ01AEWGV unknown (see comment) Homsap IGHV3-74*03 F 104 52.94 72/136 nt 8 7 X 8.7.X [2.17.11.X] null + No rearrangement found stop codons gcctctggattcacatttagtaactactggatgagctgggtccgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22074 JY8QFUQ01BL6G3 No results 22075 JY8QFUQ01AV7PZ unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD1-1*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDHIWAFDF## out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 168 to 168 in the user submitted sequence), (cause frameshift); cctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcagactctgtgaagggccgaatcaccatctccagagacaatgccaagaactcacttTtttctgcaaatgaacaccctgagagacgacgacacggctgtgtattactgtgcgagagaccacatttgggcttttgatttctgggggccaagggacaaaggttaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22076 JY8QFUQ01ADKWZ productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 990 95.39 207/217 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-8*01 F 2 8 8 19 8.8.19 [1.17.38.11] CAKDGQRYCSNGVCSSFFDSW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcacctacagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcagcaattagtggtggtggtgctagtacataccacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatttgcaaatgaacagcctgagagccgacgacacggccgtatattactgtgcgaaagatggacaacgatattgctctaatggtgtatgctcgtccttctttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccggaaccaggtgacgggtgtcgtggaactc 22077 JY8QFUQ01BXQYJ productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 937 92.24 202/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD6-25*01 F 2 8 8 14 8.8.14 [2.17.38.11] CAREVIPTATYGMDLW in-frame - Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) gcgtctggattcacgtttagtagatttgtcatccattgggtccgccagactccaggcaaggcgctggagtgggtggcagttatttggtatgatggaactaacaaatactatacagaatccgtgaagggccgattcaccatctccagagacaattccaagaacatgctgtatctgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagaggtcataccaactgccacctacggcatggacctctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaac 22078 JY8QFUQ01BWXXP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 783 84.79 184/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-10*02 F 2 8 8 20 8.8.20 [1.17.38.11] CTKTRVVLGITFPFYIYGLDVW in-frame + Low V-REGION identity (84,79% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release ctctggattcacgttcgacaactatgccatgagctgggtccgccaggcaccaggaaaggggctggagtgggtctccagtattagtggtaatggagaaattgtacaccacgcagacgccgtgaagggccggttcaccatctccagagacaactccaagaacacgctgtttttgcaaatgaatggagtgagagacgacgacacggccatttactactgtacgaaaacacgcgttgtgttgggaattacatttccgttctatatctatggtctggacgtctggggccaagggaccacggtcaacgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttc 22079 JY8QFUQ01BY7OJ productive Homsap IGHV4-39*02 F (see comment) 772 83.33 185/222 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-2*02 F 3 10 7 22 10.7.22 [2.17.38.11] CATIVPSSVTALINDQGRFYFDHW in-frame - Low V-REGION identity (83,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gtctccggtgtctccattagtagtgatacttaccactggggctggatccgccagcccccagggaaggaaccggagtggatcggcaagatctctaacagtgggagcaccttctacagtccgtctttccagagtcgagtcactgtatcgatggaagcgcccaagaaccacatctccctgaaactgaggtctgtgaccgccgcagacacggctgtttattattgtgcgacaatagtcccctcttctgtgacagcacttattaacgatcaaggaaggttctactttgaccactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22080 JY8QFUQ01C12ZU unproductive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 942 92.27 203/220 nt 91.82 202/220 nt Homsap IGHJ4*03 F (see comment) 123 72.92 35/48 nt Homsap IGHD3-16*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDQSLGDARGF*HL# out-of-frame - stop codons Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtcgctatagcatgaactgggtccgccaggctccagGggaaggggctggagtgggtctcaactattagtagtcatagtatttacatatactatgcagactcagtggagggccgattcaccgtctccagagacaacgccgagaactcgctgtatctgcacatgaacaccctcagagccgacgacacggctatatattactgtgcgagagatcaaagtctgggggatgcccgaggcttttgacatctgggggccaagggacaatggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22081 JY8QFUQ01B7K8E productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 928 91.78 201/219 nt 90.87 199/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'TCA' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); gcctccggattcacctTttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctTCAcgggactaaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacacgcacccccaagatggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22082 JY8QFUQ01B753F productive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSGYYSTGYW in-frame + ctctggattcacctttagtggctattggatgagttgggtccgccaggctccggggaagggtctggagtgggtggccaacatagagaaagatggaagtgacataaagtatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcattgtatttacaaatgaacaacctgagagccgaggacacggctgtgtattactgtgctattagtagtggttattactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaaacgtggtcgtcgcatgcctggtccagggcttcttcccccc 22083 JY8QFUQ01BJ4C7 No results 22084 JY8QFUQ01AW1OG No results 22085 JY8QFUQ01CXATF productive Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-3*01 F 2 8 8 15 8.8.15 [1.17.38.11] CARESWWSGFYGWYDPW in-frame + cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactca 22086 JY8QFUQ01B0C8G unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 968 94.04 205/218 nt Homsap IGHJ4*03 F (see comment) 96 66.67 32/48 nt Homsap IGHD1-20*01 F 3 8 8 X 8.8.X [1.17.38.11] CANASPRITGTYFYYYGMDV# out-of-frame + Other possibilities: Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) cctctggattcatcttcagtagctatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtagtggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctgggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtcggaaactca 22087 JY8QFUQ01DM1XR productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 915 90.91 200/220 nt 90.0 198/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD3-16*02 F 1 8 8 16 8.8.16 [2.17.38.11] CAKDPQQLLEDINWFDPW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 86 of V-REGION: 'AT' (2 nucleotides at position 166 to 167 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 93 of V-REGION: 'G' (1 nucleotides at position 188 to 188 in the user submitted sequence), (cause frameshift); agcctctggattcacctttcgcagctatgccatgagctgggtccgccaggctccaggaagggggctagagtgggtctcatctatcagtggtagtggtgataaaacaaagtacgcagactccgtgaagggccggttcaccatctccagagacaacgccaggaacacATtttttatctgcaaatggacaGgcctcagagccgaggacacggccgtctattactgtgcgaaagatcctcagcagttattggaagacataaactggttcgacccctggggccagggcacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22088 JY8QFUQ01BPG47 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22089 JY8QFUQ01CJ2DS productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 901 90.41 198/219 nt 89.95 197/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [2.17.38.11] CARDRLTISALDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggGggcttgagtgggtctcagctatagctgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22090 JY8QFUQ01B8VG4 productive Homsap IGHV3-72*01 F 993 94.17 210/223 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*01 F 3 8 10 15 8.10.15 [1.17.38.11] CSRVGGWVGRADGFDLW in-frame + ctctggactcaccttcagtgcccagtacttagactgggtccgccaggctccagggaagggactggagtgggttggccgtattagaagcaaaactaacagttacaccacagaatacgccgcgtctgtgaaaggcagattcaccatctcaagagatgattctacgaactcactgtatctgcaaatgaacagcctgaaaaccgaagacacggccgtgtactactgttctagagtcggcgggtgggtggggcgtgctgatggttttgatctgtggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 22091 JY8QFUQ01CDXA6 unproductive (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F 1075 97.78 220/225 nt 96.89 218/225 nt Homsap IGHJ6*01 F 90 60.32 38/63 nt Homsap IGHD1-26*01 F 3 10 9 X 10.9.X [1.17.38.11] CTRGSSRGGEI**ELL*##DFW out-of-frame - stop codons in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 79 of V-REGION: 'AC' (2 nucleotides at position 151 to 152 in the user submitted sequence), (cause frameshift); tccggggacagtgtctctaccaacagagctgcttggaactggatcaggcagtccccatcgGagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtgtctgtgaaaagtcgaataaccatcaaACcccagacacatccaagaaccagttctccctgcagttgaattctgtgactcccgaggacacggctgtgtattactgtacaagagggtccagccgcgggggggagatatgatgagaactactatgagctggacttctgggggccagggaagcccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 22092 JY8QFUQ01C2553 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 873 89.4 194/217 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD6-6*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARGRATGLVDWFDPW in-frame - ctctggattcaccttcaccaactacgccatgacctgggtccgccaggctccagggaaggggctggagtggatctcgactgttgtgggtggcggtggtaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattcccagaacacgctgtatttgcaaatgtacaatttgggagccgaggacacggccctatattactgtgcgagaggtagagcgactggtctggtggactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22093 JY8QFUQ01C8FJA No results 22094 JY8QFUQ01AFSLP unproductive Homsap IGHV3-11*01 F 1018 96.35 211/219 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [2.17.38.11] CAVDCTSISCNGD## out-of-frame - gcctctgggttcaccttcagtgactactacatgagctggatccgccaggctccagggaaggggctggagtggctttcatatattagtagtgctggtagtaccatatactacgcagactctgtgaggggccgattcaccatctccagggacaacaccaagaactcactgtatctgcaaatgaacagcctgagggccgaggacacggccgtgtattactgtgcggtagattgtactagtatcagctgcaacggagactggggccaggggaaccctggtcaccgtctcctcggcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22095 JY8QFUQ01CGR44 productive (see comment) Homsap IGHV3-30*10 F (see comment) 729 82.03 178/217 nt 81.57 177/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 1 8 8 11 8.8.11 [1.17.38.11] CLAEVGGRQFDNW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (82,03% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctctggattcaccGttcaggaatcatgctatgcactgggtccgccaggcaccaggcaagggactagagtgggtggcacgcatctcacatgatggtgttagcgagatgtatacagaccccgtgaggggccgattctccatctccagagacaattccaaaagtattctatctctgcaaattaatggcctgagaagtgacgacacggctgtgtattattgtttggccgaagtgggaggccgacaatttgacaactggggccagggaaccctggtcactgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22096 JY8QFUQ01BR48U productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 847 87.67 192/219 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-10*01 F 3 8 8 10 8.8.10 [2.17.38.11] CIMDLVGRADYW in-frame + ccctctggattcgccttcagttggtattggatgcactgggtccgccaagttccagggaaggggctggagtgggtcgcacgtatgaacgaagatgggagcatcagaaactacgcggactacgtgaagggccggtttaccatctcaagagacaacgccgagaacacactttatctgcaaatgagcagtctgagagccgaggacacggctatatattactgtataatggatctggttgggagggcggactattggggccagggaaccctggtcaccgtctcctcagcatcccccgaccgagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22097 JY8QFUQ01CWZ6M productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 832 87.5 189/216 nt 86.57 187/216 nt Homsap IGHJ1*01 F (see comment) 188 84.62 44/52 nt Homsap IGHD3-10*01 F 2 8 7 15 8.7.15 [2.17.38.11] CARDGDFGSYQEFFQYW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01CWZ6M ; 8 AA in Homsap_IGHV3-21*01) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'A' (1 nucleotides at position 80 to 80 in the user submitted sequence), (cause frameshift); gcctcgggatttagGattcagtgactacagcctgagctgggtccgccaggctccagggaaggggccggagtgggtcgcaAttcattagtcgtaacagtcacataagctacgcggactcagtgaggggccgattcaccatcgccatggacaactccaagaactcactgcttctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagatggtgattttgggagctaccaggagttcttccaatactggggccagggcaccctggtcaccgtgtcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22098 JY8QFUQ01C2DKL productive Homsap IGHV3-7*01 F 1035 97.7 212/217 nt Homsap IGHJ1*01 F (see comment) 152 76.92 40/52 nt Homsap IGHD2-21*02 F 2 8 8 10 8.8.10 [1.17.38.11] CSNGYGDFPRRW in-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) ctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactgttcgaatggttacggtgacttcccgcgtaggtggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22099 JY8QFUQ01BZL66 unproductive Homsap IGHV3-15*04 F 917 90.18 202/224 nt 88.84 199/224 nt Homsap IGHJ3*02 F (see comment) 115 70.0 35/50 nt Homsap IGHD6-25*01 F 3 8 10 X 8.10.X [1.17.38.11] CITGRTPSAWGY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 162 to 162 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 183 to 183 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'GA' (2 nucleotides at position 197 to 198 in the user submitted sequence), (cause frameshift); cctctggattcactttcagtaacgcctggatgtactgggtccgccaggctccagggaaggggctggagtgcgttgggcgtattggacgcagagttgatgacgggacaatagactacgctgcacccgtgaaaggcagattcatcatgtcaagagatgattcaAaaaaatatgttgtatctgcaAaatgaacagcctgGAaaaatcgaagacacggccatgtattattgtatcacaggtcgtacaccgtcggcttggggatacggggggccagggaaccatggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22100 JY8QFUQ01C0J5I productive Homsap IGHV3-48*02 F, or Homsap IGHV3-48*04 F 949 93.52 202/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDRRGYSYEMDYW in-frame - tctggattcaccttcagtgtccatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcataccttagtagtggtagtgataccatatactacgcagactctgtgaggggccggttcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagtggcctgagagacgaggacacggctgtttattactgtgcgagagatcggcgtgggtatagttatgaaatggactactggggacagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22101 JY8QFUQ01BPG6V unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 827 87.44 188/215 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPHRHGRL# out-of-frame - Other possibilities: Homsap_IGHJ4*01 and Homsap_IGHJ4*03 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) cctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggagagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcggggcccccccacaggcatggacgtctgggggcccagggaccatggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22102 JY8QFUQ01CE6W2 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 913 91.67 198/216 nt 91.2 197/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 7 8 10 7.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 20 in the user submitted sequence), (cause frameshift) ctctggattcagcttaagttctatggcatgaactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22103 JY8QFUQ01BERNX productive Homsap IGHV1-2*02 F 903 91.59 196/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [0.17.38.11] CARGGTVTAGGPRIVFGYW in-frame - tggctacaccttcaccgactactatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggatggatcaaccctgacggtggtagcacaaagtatgcacagaaatttcagggcagggtcgccgtgaccagggacacgtcaattagcacagcctacattgaggtgaccagactgacatctgacgacacggccgtgtattattgtgccagaggagggactgtgacagcaggtggtcctcgtattgtctttgggtactggggccagggaacgttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22104 JY8QFUQ01BAB5T productive (see comment) Homsap IGHV3-72*01 F 1043 96.43 216/224 nt 95.98 215/224 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD4-11*01 ORF 2 8 10 13 8.10.13 [1.17.38.11] CVRGLHSNYYGMDVR in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtgaccactacatggactGgggtccgccaggctccagggaaggggctggagtgggttggccgtagtagagacaaagttaacagttacagcacagaatacgccgcgtctgcgaagggcagattcaccatctcaagagatgaatcaaagaactcactgtatctgcaaatgaacagcctgaaaagcgaggacacggccgtgtattactgtgttagaggcctacacagtaattactacggtatggacgtcaggggccaagggaccacggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22105 JY8QFUQ01B1PG0 No results 22106 JY8QFUQ01CFH88 unproductive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 954 93.55 203/217 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD1-26*01 F 1 8 8 X 8.8.X [1.17.38.11] CARAPESGSYPAEYFQH## out-of-frame - Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) gactggattcaccttcagtaactataccatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctggtttgatggaagaaatcaatactatgcagattccgtgaagggccgattcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagaggcgaagacacggctgtatattactgtgcgagagcccccgagagtgggagctacccggctgaatacttccaacactgggggccagggcaccccagtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctcccaagagcacctctggggggcacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22107 JY8QFUQ01BNGCY productive (see comment) Homsap IGHV4-61*02 F 829 86.76 190/219 nt 86.3 189/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-18*01 F 3 10 7 15 10.7.15 [1.16.38.11] CARDTGQTYGRGPLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 49 of V-REGION: 2 nucleotides (from position 67 in the user submitted sequence), (cause frameshift) tctctggtgcctccataaataggggtaattattactggaactggatccggcagcccgccgggaaggctggaatggattggccgaatctatacaagtgggagcaccatctacaacccctccctcgggggtcgagtcaccatgactgtagacccgtccgagaatcagttcttcctgagactgagttctgtgaccgccgcagacacggccgtttatttttgtgcgagagacactggacaaacctacggtcggggccctttggactactggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22108 JY8QFUQ01AYSDL No results 22109 JY8QFUQ01CAQJA productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 977 94.5 206/218 nt 94.04 205/218 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtcagtactggatgtactgggtccgccaagctccagggaaggGggctggtgtgggtctcacgtattaatggtgatggaagtagcacaagctatgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacaccctgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22110 JY8QFUQ01BJT4G productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22111 JY8QFUQ01CB7ZQ productive Homsap IGHV3-9*01 F, or Homsap IGHV3-9*02 F (see comment) 281 81.4 70/86 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-24*01 ORF 3 X X 14 X.X.14 [X.X.28.11] CVKDRKGSNWYYFENW in-frame - Low V-REGION identity (81,40% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagagacaatgccaggaactccctctacttgcaaatggacagtctgagacctgatgacacggccttctattactgtgtaaaagatcgaaagggcagcaattggtactactttgagaactggggccagggaaccctggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22112 JY8QFUQ01DLR69 productive Homsap IGHV3-7*01 F 919 91.32 200/219 nt Homsap IGHJ4*02 F (see comment) 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 14 8.8.14 [2.17.38.11] CARVRGYYGGQYFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) cctctgggattcacctttagtagttattggatgacctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaaggaagatgggaatgataaatactatgtcgactctgtgaggggccggttcaccatctccagagacaacgccaagagctcactgtttctgcaagtgaacagcctgagagccgacgacacggctgtttattactgtgcgagagttcgaggttattacggtgggcagtactttgattcctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22113 JY8QFUQ01B32HS No results 22114 JY8QFUQ01BDDP0 No results 22115 JY8QFUQ01AFX4M No results 22116 JY8QFUQ01CIFVA productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F (see comment) 692 80.47 173/215 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD6-6*01 F 3 8 7 9 8.7.9 [1.17.38.11] CARLDGHFDLW in-frame - Low V-REGION identity (80,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctgggttcaccatcagtcactactccatggcctgggtccgccaggctccgggaaaggggctggagtgggtctcattaatttatcccggcgggagcacattccacgcagactccgtgagggggcggcttatcatctccagagacgaatccaagagtgaactgtatcttcggatgaagaaagtgaaagtcgaagacacggccgtatattattgtgcgagactcgacgggcacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22117 JY8QFUQ01B6XEV No results 22118 JY8QFUQ01BUDX2 No results 22119 JY8QFUQ01AB4WK productive (see comment) Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 1093 98.67 222/225 nt 97.78 220/225 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 10 13 8.10.13 [2.17.38.11] CTRDRNICNPPFDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 163 to 163 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'A' (1 nucleotides at position 199 to 199 in the user submitted sequence), (cause frameshift); gcttctggattcacctttggtgattatgctatgagctggttccgccaggctccagggaaggggctggagtgggtaggtttcattagaagcaaagcttatggtgggacaacacaatacgccgcgtctgtgaaaggcagattcaacatcttaagagatgattccAaaaagcatcgcctatctgcaaatgaacagcctgaaAaaccgaggacacagccgtgtattactgtactagagataggaacatctgtaaccctccctttgactactggggccagggaaccctggtcatcgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22120 JY8QFUQ01BSCX8 No results 22121 JY8QFUQ01B6LRP productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22122 JY8QFUQ01CBRZI unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*04 F or Homsap IGHV3-30-3*03 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CARGMATAES## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcattagcgaagctatgcactgggtccgccaggctccaggcaaggGggcttgagtgggtggcactaatatcatatgatgagagtgataaacaatatgtagactccgtgaagggccgattcaccatctccagagacaattccaagaacacactatatctgcaaatgaacagcctgagacgtgaggacacggctgtgtattactgtgcgagaggcatggctactgcggagtcctggggccagggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22123 JY8QFUQ01BPRUL unproductive Homsap IGHV3-33*03 F 932 92.2 201/218 nt Homsap IGHJ6*02 F 94 61.29 38/62 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [1.17.38.11] CARDGGAVAGW#VVDVW out-of-frame + cgtctggattcattttcaacagctatgccatgcactgggtccgccaggctccaggcaagggcctggagtgggtggcagttatatggtttgatggaagtaaaaaatattacgcagactcagtgaagggccgatccaccgtctccagagacaactccaagaacacgttgtatctgcaaatgaacagcctgagagccggggacacggccgtgtattattgtgcgagagatgggggagcagtggctggttggacgttgtggacgtctggggccaagggaccacggtcgaccgtcgcctcagcctccagccaaggccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22124 JY8QFUQ01B5D2F productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD2-21*02 F 2 8 8 14 8.8.14 [1.17.38.11] CARQTGDYYYFGLDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); ctctggattcaccttGcagctcccattggatgagctgggtccgccagactccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgtgaagtattatgtggactctgtgaggggccgagtcaccatctccagagacaacgcccggaactcactgtatctgcagatgagcagcctgagagccgaggacacggctctgtattactgtgcgagacaaactggggactattattacttcggcctggacgtctggggccaaggaaccacggtcaccgtctcttcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22125 JY8QFUQ01CFWZO unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 168 92.31 36/39 nt 8 X X 8.X.X [2.3.X.X] null + No rearrangement found gcctctggattcacctttaacagccatgccatgagttgg 22126 JY8QFUQ01C1C5K productive (see comment) Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD4-17*01 F 3 7 8 14 7.8.14 [2.17.38.11] CATSPFTVTTGKDAYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 36 of V-REGION: 1 nucleotides (from position 22 in the user submitted sequence), (cause frameshift) gcctctagattcacctttaatggtactggatgagttgggtccgccaggctccaggaaaggggctggagtggctggccaacataaagccggatggaaatgagaaatgctatgcggactctgtgaagggccgattcaccatctccagagacaacgccaagagttcgctgtttctgcaaatgaacagcctgagagccgaggacacggctgtatatttctgtgcgacctccccctttacggtgactactgggaaggacgcctactggggccagggaaccctggtcctcgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22127 JY8QFUQ01CR8C5 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 964 93.15 204/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-3*01 F 2 8 8 17 8.8.17 [2.17.38.11] CAKIDSRNYDFWSGYYAHW in-frame + gcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaattccgagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgcgcgaaaatagatagtcggaattacgatttttggagtggttattatgcacactggggccagggatccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtgggaactcag 22128 JY8QFUQ01BNYOH productive (see comment) Homsap IGHV3-7*01 F 959 93.58 204/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 14 8.8.14 [1.17.38.11] CARETLPLGVGGFDNW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); cctctggattcacatttagtGaattattggatgatctgggtccgccaggctccGagggaaggggctggagtgggtggccaacataaAaccaagatggaggtgacatggcctatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactctctgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagagacactcccccttggtgttgggggttttgacaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22129 JY8QFUQ01CLL77 productive (see comment) Homsap IGHV4-31*02 F, or Homsap IGHV4-31*03 F or Homsap IGHV4-31*04 F 1028 96.38 213/221 nt 95.93 212/221 nt Homsap IGHJ6*02 F (see comment) 238 87.1 54/62 nt Homsap IGHD2-8*01 F 2 10 7 14 10.7.14 [1.17.38.11] CASTSGSDYHYGMDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 46 of V-REGION: 'C' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift); tttctggtggctccatcagcagtggtggttactactggagctggatccgccagtaccCccgggaagggcctggagtggatggggtacatctattacagtgggagcacctattacaacccgtccctcgagagtcgagttaccatatcagtagacacgtctaagaaccagttctccctgaagctgagctctgtgattgccgcggacacggccgtctattactgtgcgagtactagtgggtcagactaccactacggaatggacgtctggggccaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 22130 JY8QFUQ01BCTYE unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 806 85.78 187/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 88 64.0 32/50 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGFSAWGQDAFDI## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccgattcaccatctccagagacaactccaataactcagtgtatctgcagatgaacagggtgacagccgacgacgcggcagtctatttctgtgccagaggcttcagtgcctggggtcaggatgctttcgacatttgggggccacgggacctttgtcaccgtctcttcagcctccaccaagggcccattccggtccttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtggacggtgtcgtggaactc 22131 JY8QFUQ01AXZ3Q productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 92.66 202/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22132 JY8QFUQ01C4HGG No results 22133 JY8QFUQ01CRZTN unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 87.61 191/218 nt 8 8 X 8.8.X [2.16.38.X] null + No rearrangement found in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift) gcctctggattcacctttaccacctccgccatggcctgggtccgcaggttccagggaaggggctgaagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22134 JY8QFUQ01AHEE4 productive (see comment) Homsap IGHV3-7*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD5-12*01 F 1 7 8 9 7.8.9 [2.17.38.11] CARDQVTEDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) gcctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22135 JY8QFUQ01DFTAV unproductive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 833 87.16 190/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-6*01 F 2 8 7 X 8.7.X [2.17.38.11] CVRSYSRTSE#FDYW out-of-frame + stop codons in CDR2-IMGT, from codon 64 of V-REGION: 1 nucleotides (from position 102 in the user submitted sequence), (cause frameshift) gcgtctggattcagtttcagtacctttggcatgagttggatccgccagacgccaggcaaggggctggagtgggtgacagttatatggtcggatggaactaaaaaaattatgcagactccgtgaagggccgattcaccatctccagagacaatgtcaagaacacggtttatctgcagatgagcagcctaagagtcgaggacacgggcgtatattattgtgtgaggtcgtatagtaggacatctgagttttgactactggggcccgggaacccaagtcaccgtctccgcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22136 JY8QFUQ01BAQLF productive Homsap IGHV3-7*03 F 847 87.67 192/219 nt Homsap IGHJ6*03 F (see comment) 156 78.43 40/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [2.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) gcctccggattcacttttagtgactattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccaccacaaacgaggacgagactaagaaatactctgcggactctgtgaggggccgattcaccatctccagagacaacgccaagaactcactgtacttgcagatgagcagcctgagagccgacgacgcggccgtctattattgtacgagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctccgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatcgggaacgtggtcatcgctgcctggtccagggctcttccccca 22137 JY8QFUQ01AKUO2 No results 22138 JY8QFUQ01DAH7T productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 955 93.15 204/219 nt 91.32 200/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-7*01 F 2 9 7 12 9.7.12 [2.17.38.11] CVRHRRLELLPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'AATA' (4 nucleotides at position 25 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 61 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift); in CDR1-IMGT, from codon 34 of V-REGION: 3 nucleotides (from position 22 in the user submitted sequence), (do not cause frameshift) gtctctggtgactccatcagcagtAATAgttttctactggggctggatccgccagcccccCAgggaagggggctggagtggattgggaatatctattatagtgggagcacctactacaaccCcgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22139 JY8QFUQ01CS2TL productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [2.17.38.11] CARDCDSGECNFDYW in-frame + gcctctggattcagcttcagtacctataacatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccataagtagtggtagtacttacatatatcacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaagacactttacctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagattgtgacagtggtgaatgtaactttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22140 JY8QFUQ01DJEW5 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 923 91.28 199/218 nt 90.83 198/218 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [1.17.38.11] CASYGQWL in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 78 to 80 in the user submitted sequence), (do not cause frameshift); cctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagccacagcggccctgggctgcctggtcaaggacctacttccccgaaccggtgacggtgtcgtggaact 22141 JY8QFUQ01DB11U productive (see comment) Homsap IGHV3-48*02 F 960 93.18 205/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [2.17.38.11] CARDMIIFGGALDNW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'C' (1 nucleotides at position 108 to 108 in the user submitted sequence), (cause frameshift); tgcctctggattcgccttcagtagttccagcatgaactgggtccgccaggGgtccagggaaggggctggagtggAttttcacacattagGgggtagtagtagtaccaCcccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtccgtcgcatcgcctggtccagggcttcttcccccgag 22142 JY8QFUQ01B4LNG No results 22143 JY8QFUQ01CUNKZ No results 22144 JY8QFUQ01BG7JJ No results 22145 JY8QFUQ01AV68L unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 860 88.13 193/219 nt 87.67 192/219 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR1-IMGT at codon 35 of V-REGION: 'C' (1 nucleotides at position 19 to 19 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcCaaaaagtatggcatgaactggctccgccaggctccagggaaggggctggantgggtcgcaaccattcgcagtagtggtacttccatacactatgccgactccgtgaagggccgattcactatcaccagagacaacgccaacaactcactgtatctgcaattgaacagcctgggagtcgaggactcggctgtgtatttctgtgcgagaggggccggcgcagaaggtaaaggtggtatggacgtctggggccaagcgggactacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 22146 JY8QFUQ01COR8B productive Homsap IGHV3-7*01 F 806 85.78 187/218 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD3-16*01 F 3 8 8 16 8.8.16 [1.17.38.11] CARVKASGVRPMNAYDMW in-frame + cctctggattcgtgtttagtgactactggatgagttgggtccgccagcctccagggaaggggctggagtgggtggccagcattaaggaagatggacgtgagacgtactctgtggactctgtgaagggccgtttcaccatctccagagacaacgccgtacgttctctccttctacaaatgaacagactgagagtcgaggacacggctgtttatttctgtgcgagagtcaaggcttccggggtnaggcccatgaatgcctatgatatgtggggccaagggacattggtcaccgtctcttcagcctccaccaaggcccatcggtcttcccccctggcaccctcctccaagagcaccctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 22147 JY8QFUQ01B7R66 No results 22148 JY8QFUQ01B0JYF No results 22149 JY8QFUQ01B4SDT productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 823 87.04 188/216 nt 86.11 186/216 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD1-26*01 F 3 8 7 11 8.7.11 [2.17.38.11] CATLRGGYFRLLG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 64 of V-REGION: 'A' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); gtctctggtgcctccatcaggagttattattggagttggatccggcagccCcccaggaaagggactggagtggattggttatattaattatgttgggggAcaccgattacaacccctccctcaagagtcgagtctccatgtcagcagccacgtccaagaaccaggtcttcctgcagctgacctctgtgaccgctgcggacaccgcctattatttctgtgcgacactgagaggggggtactttcgactactgggggccgggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22150 JY8QFUQ01CJ3LH unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 941 92.66 202/218 nt Homsap IGHJ3*01 F (see comment) 160 80.0 40/50 nt Homsap IGHD6-13*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDLRVSTMASD#DVW out-of-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcagtttcagtacttataacatgaattgggtccgccaggctccagggaaggggctggagtgggtctcatccatgggtagtagtagtatttacatatattacgcagactcagtgaagggccgattcaccatctccagagacgacgccaagagttcactgtatctgcaaatgaacagcctgagagccgaggacacggctatatattactgtgcgagagacttaagggtctcgactatggcatccgatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaaggactacttccccgaaccggtgacggtgtcgtggaactc 22151 JY8QFUQ01BHHPO unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 1 8 8 X 8.8.X [2.17.38.11] CAKGV*QWL##DFDCW out-of-frame + stop codons in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtagttTttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaagggggtatagcagtggctggtacgactttgactgctggggccagggaaccctggccaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 22152 JY8QFUQ01ADN1T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 92.99 199/214 nt 8 7 X 8.7.X [1.17.38.X] null + No rearrangement found in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaAaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 22153 JY8QFUQ01CJVC7 productive Homsap IGHV3-7*01 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD3-10*01 F 2 8 8 18 8.8.18 [1.17.38.11] CAKARIYFYGSGSYSLFDYW in-frame - cctctggaatcaccttgagtccctattggatgacctgggtccgccaggctcccgggaaggggctggagtgggtggccaacataaaccaagatggaggtgagagaaattatgtggcctctgtgaggggccggttcaccatctccagagacaacgccaggaattcactgtatctgcaaatgaacagcctgagagtcgacgacacggctgtatattattgtgcaaaagccaggatctatttttatggttcggggagttattccctctttgactactggggccagggagccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22154 JY8QFUQ01CBLRN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 16 to 16 in the user submitted sequence), (cause frameshift); cctctggattcacctTttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcttccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactc 22155 JY8QFUQ01BYZGI unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ4*02 F 105 68.75 33/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CMNELGYCSGGG# out-of-frame + in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); cctctggattcacTttttagcagccatatgatgagttgggtccgccaggctccagggaaggGggctggaatgggtctcaactattcgtgccagtggtgataggacacactatgcagactccgtgaggggccgcttcaccatctccagagacaattccaagaacacgctgcatttgcaaatgtacagcctgagagtcgaggacacggccgtatactactgtatgaacgaactcggatattgtagtggtgggggggggaccagggagccctggtctccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 22156 JY8QFUQ01B9LAE productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 856 88.13 193/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [2.16.38.11] CTRDIGGRYSYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 43 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) gcctccgggattcacctttagtagtttctggatgcactgggtccgcaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgcctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22157 JY8QFUQ01BOOGP productive Homsap IGHV4-61*01 F, or Homsap IGHV4-61*08 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-26*01 F 3 10 7 15 10.7.15 [1.17.38.11] CARGGSGGSYWNLIRDW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) tctctgatgactccgtcagcagtggtcgttactactggagttgggtccggcagcccccagggaagggactggagtggattggtcatttctatcacattgggggcactaagtacaacccctccctcgcgagtcgagtcaccatatcagtagacacgtccaagagccagttctccctgatgctgaactctgtgaccgctgcggacacggccgtatatttctgtgcgagaggtgggtccggtgggagctactggaatctgatccgggactggggccagggaaccctggtcaccgtctactcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 22158 JY8QFUQ01DL109 unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift); ctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccaaccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22159 JY8QFUQ01BQ7IE productive (see comment) Homsap IGHV3-7*03 F 851 88.07 192/218 nt 87.16 190/218 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD4-11*01 ORF 2 8 8 19 8.8.19 [1.17.38.11] CARDRYSSDSSYYMPNWLDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 57 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 52 of V-REGION: 'G' (1 nucleotides at position 72 to 72 in the user submitted sequence), (cause frameshift); cctctggattcacgtttggttcgtattggatgagttgggtccgccaggctccagggGAagggggctggagtGgggtggccaacattcacgaagaaggaagtgaaaagaattatgtggactctgtgaagggccggttcgtcatctccagagacaacgccaagaattccctctatctgcaaatgaacagcctgagagtcgaggacacggccatatattattgtgcgagagatcgatatagtagcgattccagttactacatgcccaactggctcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 22160 JY8QFUQ01AY0CF productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 936 92.63 201/217 nt 92.17 200/217 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); ttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggaaaggcctggagtggatggGggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22161 JY8QFUQ01B4PHJ productive Homsap IGHV3-49*03 F, or Homsap IGHV3-49*05 F 849 87.0 194/223 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD4-23*01 ORF 3 8 10 14 8.10.14 [1.17.38.11] CSRRSTLVTGYVFDKW in-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) ctctggaatcaactttcgtgatcatgccatgagctggttccgccaggttccagggaaggggctggagtgggtaggtttcattagaagttctcaatacggtggagatacagaatacgccgcgtctgtggaaggcagattcaccatctcaagagacgattccaaaagcatcgcctatttggatatgaatagcctgaaaatcgacgacacagccctatattactgttcccggaggtcgacgttggtgactggatacgtctttgacaagtggggccagggcaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22162 JY8QFUQ01A4FKP No results 22163 JY8QFUQ01CH8AQ unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F or Homsap IGHV3-21*03 F or Homsap IGHV3-21*04 F or Homsap IGHV3-48*01 F or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F 163 92.11 35/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found cctctggattcaccttcagtgtccatagcatgaactgg 22164 JY8QFUQ01DSHGG productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 888 89.55 197/220 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacatttcgccttttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggaatggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22165 JY8QFUQ01BV2N1 No results 22166 JY8QFUQ01DB2AC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt Homsap IGHJ4*02 F (see comment) 87 64.58 31/48 nt Homsap IGHD6-19*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKGYSSGWYDFDCW in-frame + Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ5*01 (highest number of consecutive identical nucleotides) cctctggattcacctttagtagttttgccatgacctgggtccgtcaggctccagggaaggggctggagtgggtctcaactattcattataatggtgataacacatactacgcagactccgtgaggggccgattcaccatctccagagacgattccaagaccacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaggggtatagcagtggctggtacgactttgactgctggggccagggaacccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 22167 JY8QFUQ01B8G5P unknown (see comment) Homsap IGHV4-30-2*01 F, or Homsap IGHV4-30-2*02 F or Homsap IGHV4-30-2*03 F or Homsap IGHV4-30-2*05 F or Homsap IGHV4-30-2*06 F or Homsap IGHV4-30-4*01 F or Homsap IGHV4-30-4*02 F or Homsap IGHV4-30-4*03 F or Homsap IGHV4-30-4*04 F or Homsap IGHV4-30-4*07 F or Homsap IGHV4-31*01 F or Homsap IGHV4-31*02 F or Homsap IGHV4-31*03 F 76 94.12 16/17 nt 4 X X 4.X.X [1.X.X.X] null + No rearrangement found tctctggtggcgccatc 22168 JY8QFUQ01BY1J1 productive (see comment) Homsap IGHV4-61*02 F 879 89.09 196/220 nt 88.18 194/220 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD5-24*01 ORF 3 10 7 13 10.7.13 [1.17.37.11] CARDFGGSYNLVDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 34 to 34 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 115 in the user submitted sequence), (cause frameshift) tctctggtgactccatcagtagtgattctcactGactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttctgtgcgagagattttggaggttcctacaatttagttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22169 JY8QFUQ01CTORM unproductive Homsap IGHV3-7*01 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 8 X 8.8.X [1.17.38.11] CTTTLVWFGGV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION in FR2-IMGT at codon 48 of V-REGION: 'GG' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); cctctggattcacgtttagagactattggatgagttgggtccgccaggctcctggggaGGggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcgggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22170 JY8QFUQ01CLG7Y unproductive Homsap IGHV3-7*01 F 937 92.24 202/219 nt 91.78 201/219 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [2.17.38.11] CARWRGQQSEME#YW out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtaactattacatgagttgggtccgccaggctccagggaaggGggctggagtacgtggccagcataaaacaagatgaaggtcagacatactatgcgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatcttcaaatgaacagcctgagagtcgaggacacggctgtgtatcactgtgcgcggtggagagggcaacaatccgaaatggaagtactggggccagggaaccctggtcaccgtctctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22171 JY8QFUQ01DSPF1 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 683 79.63 172/216 nt 76.85 166/216 nt Homsap IGHJ3*01 F 106 68.0 34/50 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [2.17.37.11] CARDDGGHM#LDVW out-of-frame - stop codons Low V-REGION identity (79,63% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 42 of V-REGION: 'GT' (2 nucleotides at position 41 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'CAGG' (4 nucleotides at position 86 to 89 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'C' (1 nucleotides at position 158 to 158 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 88 of V-REGION: 1 nucleotides (from position 170 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 91 of V-REGION: 1 nucleotides (from position 177 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 94 of V-REGION: 1 nucleotides (from position 187 in the user submitted sequence), (cause frameshift) atgtctggattcacatttagaagctattcctgaaattgggGTccgcccaggctccagggaaggggctggaatgggtctcagctgtCAGGtggtggtggggggcgccgacgaaactacgcggagtccgtgaagggccggttcaccatctccagaggcnCaattcagggggacggtgttctacaatgaacagcctagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgacttagatgtctggggccaagggacaatggtgcagcgtctctccggcctccaccaaggggcccatcgggtnttccccctgcaccctcctcccaagagccacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccgggtgacggtgtcgtggaactcaggc 22172 JY8QFUQ01BY1PJ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 963 94.01 204/217 nt 93.09 202/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD2-8*01 F 2 8 8 8 8.8.8 [1.17.38.11] CARDNYGDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift); ctctggattcaGccttcagtagctactggatgcactGgggtccgccaagctccagggaaggggctggtttgggtctcacgtgttaatggtgatgggggtaggacagcctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacactctctatctccaaatgaacagtctgagagccgaggacacggcaatatattactgtgcaagagataattacggtgactactggggccagggaaccctggtcacagtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22173 JY8QFUQ01CIYD1 unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt 8 8 X 8.8.X [1.17.38.11] CTTTLVWFGGV (see Functionality comment) out-of-frame - IMGT/JunctionAnalysis gives no results for this JUNCTION ctctggattcacgtttagagactattggatgagttgggtccgccaggctcctgggagggggctggagtgggtggccaacataaagcaagatgcaagtgaggaatactatgtggactctgtgaagggccggttcaccatctccagagacaacgccaagagctcactgcatttgcaaatgaacagcctgagagccgaggacacggctatgtattactgtacgaccacattagtatggttcgggggagttaggccagggaacccaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22174 JY8QFUQ01BMR9L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 932 92.2 201/218 nt 91.74 200/218 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-10*01 F 2 8 8 13 8.8.13 [1.17.38.11] CANWLSGTHSKFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift); gctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggggaggggctgcagtgggtctcagcaattagtggaaAatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtatactactgtgcgaattggctttcggggacacattctaagtttgactactggggcaagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22175 JY8QFUQ01AGYSC No results 22176 JY8QFUQ01B21BT productive Homsap IGHV3-13*01 F 967 94.44 204/216 nt Homsap IGHJ5*02 F 255 100.0 51/51 nt Homsap IGHD3-9*01 F 1 8 7 13 8.7.13 [2.17.38.11] CARGSSKAYNWFDPW in-frame + ccctctggattcacgttcagtaattacgacatgcactgggtccgccaacctagaggaagaggtctggagtgggtctcagctattggcactggtggtgacacatactatccagactccgtgaagggccgattcaccatctccagagaaaatgccaagaactccttatatcttcagatgaacagcctgagagccggggacacggctgtgtattactgtgcaagagggtcgtcaaaagcgtacaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 22177 JY8QFUQ01AONPX unproductive (see comment) Homsap IGHV3-7*01 F 992 94.57 209/221 nt 94.12 208/221 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CAKGGW*RRP*LL# out-of-frame - stop codons in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 12 to 12 in the user submitted sequence), (cause frameshift); cgacctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaagggggggtggtaacggcgaccttgactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22178 JY8QFUQ01DKQJ9 productive Homsap IGHV3-48*01 F 860 88.53 193/218 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD3-22*01 F 2 8 8 19 8.8.19 [1.17.38.11] CARASTFYYDGSGYRDVFDIW in-frame + tctctggcttcagtttgagtacttataccatgaactgggtccgccaggctccagggaaggggctggagtgggtttcactcattagtaagactagtaatgtcatatactacgcggactctgtgaagggccggttcaccatctccagagacaatgccgagaattcactgtttctgcaaatggacagcctgagtgccgaggacacgggtgtatattactgtgcgagagcttcgacgttctactacgatggcagtggttatcgtgatgtttttgatatatggggccaagggacaatggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22179 JY8QFUQ01B5F9V No results 22180 JY8QFUQ01C7SUZ productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 976 94.91 205/216 nt 93.98 203/216 nt Homsap IGHJ5*02 F 237 96.08 49/51 nt Homsap IGHD1-20*01 F 1 8 8 16 8.8.16 [1.16.38.11] CARDPVGISGSVNWFDPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 46 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagcaaccataacatgaactgggtccgccagctccagggaacgggctggagtgggtctcGatgtattggtagtagtagtagtgacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagtcgaagacacggctgtgtattactgtgcgagagatccggttgggataagtggaagtgtgaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaacggtcttccccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22181 JY8QFUQ01BMDA4 unknown (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*02 F or Homsap IGHV3-33*03 F or Homsap IGHV3-33*04 F or Homsap IGHV3-33*06 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 123 54.35 75/138 nt 8 8 X 8.8.X [2.17.10.X] null - No rearrangement found stop codons agcgtctggattcaccttcagtagctacggcatgcactgggtccgccaggccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22182 JY8QFUQ01B1Y93 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.38.11] CARGGLEPVDYW in-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22183 JY8QFUQ01CQ5SG productive Homsap IGHV1-8*01 F 822 87.38 187/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 12 8.8.12 [0.17.38.11] CARGRGYGSYADHW in-frame + tggatacagcttcagcaattatgatatcaactgggtgcggcaggccactggacaagggcttcagtggatggggtggatgaacccccacagtgccaatatcgtctacgcgcagaaatttcagggcagagtcaccatgaccagtgacgcctccataaccacagcctacatggaactgagcaacctgaaatctgacgacacggccgtgtattattgtgcgaggggccgagggtacggaagttacgctgaccactggggccagggaaccccggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22184 JY8QFUQ01AV599 productive (see comment) Homsap IGHV1-8*01 F 840 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD1-26*01 F 3 8 8 14 8.8.14 [0.17.38.11] CARVGGTHYHYGVDVW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift); cggatacaccttcaccgattatgagatcaactgggtgcgacaggccactggacaagggcttgagtggatgggaaggataaAagcccaatactggttacacagaatatgtacagaagttccagggcagagtcaccctgaccagggacacgtccatgggtacagcctacatggagttgcacagcctgagatctgacgacacggccgtgtattattgcgcgagagtcggtgggacccactaccactatggtgtggacgtctggggccaagggaccacggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22185 JY8QFUQ01CH46O productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 90.78 197/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD3-3*01 F 3 8 8 11 8.8.11 [1.16.38.11] CARFGPLTRPDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 38 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) gctctggattcaccttcagcaagtatgCccatgagctgggtccgccaggctccaGgggagggggctgcagtgggtctcagaattagtggaaatggtgctgatatatactacgcagactccgtgaacggccggttcaccatctccagagacaattccaagaacacgctatatctgcaaatgaacagcctgagagccgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactggggccagggaactttggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 22186 JY8QFUQ01CAKUG productive (see comment) Homsap IGHV3-23*05 F 820 86.3 189/219 nt 85.84 188/219 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-19*01 F 1 8 8 14 8.8.14 [2.17.38.11] CVKSTGHSGWYPFDNW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); gcctctggattcacattcagcaattatgccatgggctgggtccgccaggctccagggaaggGggctggagtgggtcgctgctattgatggcagtggtgaaagaactcactatgcagactccgaacagggccgcgtcaacatctctagagacaattccaagaacatgatatatgtgcaattgagcagcctgagagccgaggacacggccatgtattactgtgtgaagtccaccgggcacagtggctggtatccctttgacaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 22187 JY8QFUQ01BAT68 productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift); ctctggatcaccctttggttattGatggcatgagctgggtccgccaactccgggggagggggctggagtgggtctctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22188 JY8QFUQ01CQJDE unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 788 92.82 168/181 nt 8 8 X 8.8.X [2.17.25.X] null + No rearrangement found gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattga 22189 JY8QFUQ01BVL75 unproductive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 923 91.74 200/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-13*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKDPFIAATGRPWYFEYW in-frame + stop codons cctctggattcaccttcagcagctatggcatgcactggttccgccaggctccaggcaaggggctggagtgggtggcagctatctcatatgatggaattgacaaatattatgcagactccgtgaagggccgattcaccatctccagagacaatgccaaaaacacgctgtatctgcaattgaacagcctgagaagtgaagacactgctgattactactgtgcgaaagacccatttatagccgcaactggccgcccctggtactttgaatactggggccagggaaccctggtcaccgtctcctagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22190 JY8QFUQ01ATEC0 unproductive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 925 92.96 198/213 nt 92.49 197/213 nt Homsap IGHJ5*02 F 138 74.51 38/51 nt Homsap IGHD1-26*01 F 1 8 7 X 8.7.X [1.16.38.11] CARVVTATIYTGSYYFDS## out-of-frame - in FR2-IMGT, from codon 45 of V-REGION: 1 nucleotides (from position 47 in the user submitted sequence), (cause frameshift) ctatggtgcgtccttcagtgattactcctgggcctggatccgccagtcccagggaaggggctggagtggattggagagatcaatcatagtggaagcaccaactacaacccgtccctcaagagtcgaggcatcatatcaatagacatgtccaagaaccagttctccctgaacctgaactctgtgaccgccgcggacacggctgtatattactgtgcgagagtcgtcacggctacaatttatactgggtcctactactttgactcctgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22191 JY8QFUQ01C67PP productive Homsap IGHV3-7*03 F 851 88.07 192/218 nt Homsap IGHJ6*03 F (see comment) 183 84.31 43/51 nt Homsap IGHD6-6*01 F 3 8 8 8 8.8.8 [1.17.38.11] CTRRGFMDVW in-frame + Other possibilities: Homsap_IGHJ6*02 (highest number of consecutive identical nucleotides) cctccggattcatttttggtgactattggatgagctgggtccgccaggttccagggaagggcctggagtgggtggccactacaaacgaggacgaaagtgacaagcggtatgtggactctgtgaagggccgcttcaccatctccagagacaacgccaagaactcactgtatttgcaaatgaacagcctgagaggccaggacgcggccgtgtattactgtaccagaagaggattcatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 22192 JY8QFUQ01B1RYY unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 155 56.83 79/139 nt 56.12 78/139 nt 10 7 X 10.7.X [1.17.10.X] null + No rearrangement found stop codons in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactggGggctggatccgccagcccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 22193 JY8QFUQ01A6JX4 productive Homsap IGHV3-48*02 F 891 90.32 196/217 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 210 90.2 46/51 nt Homsap IGHD5-24*01 ORF 2 8 8 15 8.8.15 [1.17.38.11] CARGQKWLQVLRWFDSW in-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) ctctggattcaccttcgacagatacagtatgaactgggtccgccaggctccagggaggggactggagtggatttcatacataagtactactactagtaacagatactacgcagacgctgtgaagggccgattcaccatctccagagacaatgccaagaactcgctgtatttgcaaatggacagcctgagagacgaggacacggctgtatattattgtgcgagaggtcaaaaatggctacaagtgcttcgctggttcgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22194 JY8QFUQ01BN5HY unknown (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*02 F or Homsap IGHV4-39*03 F or Homsap IGHV4-39*05 F or Homsap IGHV4-39*06 F or Homsap IGHV4-39*07 F 165 57.45 81/141 nt 10 7 X 10.7.X [1.17.11.X] null + No rearrangement found tctctggtggctccatcagcagtagtagttactactggggctggatccgccagccccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 22195 JY8QFUQ01CBUKV unproductive Homsap IGHV3-7*01 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [1.17.38.11] CAISSDFYSTGH## out-of-frame + in FR3-IMGT at codon 88 of V-REGION: 'T' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcaacttcagaacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcattgTtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactggggcccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22196 JY8QFUQ01A896V productive (see comment) Homsap IGHV3-7*01 F 865 88.58 194/219 nt 87.67 192/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARDPYKPGSGNPGFDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); gcctctggattcaccttTtagtgactatttgatgacttgggtccgccaggctccaggaaagggactggagtgggtggccaacataaAaagaagatggacttgctacattctatgtggactctgtgagggaccgattcaccatctccagagacaacgccaagaactcactttatttgcaaatgaattacctgagagtcgaggacacggctgtttattattgtgcgagggatccctataaacctggttcgggcaatccgggctttgactactggggccagggagcgcaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22197 JY8QFUQ01CGLJ5 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 995 95.41 208/218 nt Homsap IGHJ3*02 F 232 96.0 48/50 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CARLCGNDCRNDVFDIW in-frame + cctctggattcaccttcagtacctactggatgcactgggtccgccaagttccagggaaggggctggtgtgggtctcacgtgttgatagtgatgggactagcacagtctacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacgctatatctgcaaatgaacagtctgaaagccgaggacacggctgtatattactgtgcaagattatgtggtaatgactgccgcaatgatgtttttgatatctggggccaagggacattggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcc 22198 JY8QFUQ01AMLL4 No results 22199 JY8QFUQ01AEIPV productive (see comment) Homsap IGHV1-2*02 F 930 92.99 199/214 nt 92.06 197/214 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD6-19*01 F 1 8 8 12 8.8.12 [0.17.38.11] CARGPVSGWYTDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 42 to 42 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'AACCCC' (6 nucleotides at position 81 to 86 in the user submitted sequence), (do not cause frameshift); tggatacaccttcaccgtctactatctattctgggtgcgacGgggcccctggacaagggcttgagtggatgggatggatcAACCCCaaccctaagagtggtgacacacactatgcaccgaaattccagggcagggtcaccatgaccagggacacgtccatcagcacagcctacatggaactgaataggctgagatctgacgacacggccgtgtattactgtgcgagaggccctgtcagtggctggtacactgactactggggccagggaaccctggtcaacgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 22200 JY8QFUQ01COBUV unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1001 95.02 210/221 nt 93.67 207/221 nt Homsap IGHJ5*02 F (see comment) 147 76.47 39/51 nt Homsap IGHD1-7*01 F 3 10 7 X 10.7.X [1.17.38.11] CVRHRRLELLPDY## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 37 of V-REGION: 'T' (1 nucleotides at position 30 to 30 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift); tctctggtgactccatcagcagtaatagtTttctactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggaatatctattatagtgggagcacctactacaacccgtccctcgagagccgagtcaccatatccgtagatacatccaggaaccagttctccctgaagctgaggtttgtgaccgccgcagacacggctgtgtattactgtgtgagacatagaagactggaactactcccagactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 22201 JY8QFUQ01AQ576 productive Homsap IGHV3-7*01 F 977 94.5 206/218 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.17.38.11] CAKDGYYYYHSGMDVW in-frame + cctctggattcagatttagtaactactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaggtgagaagtattatgtgggctctgtgaagggccgattcaccatctccagagacaacgccaagaactcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtatattattgtgcgaaagacggctattattattatcacagcggtatggacgtctggggccaagggaccacggtcatcgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22202 JY8QFUQ01AX5J6 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtagtagttactactgGgggctggatccgccagcCccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggtccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22203 JY8QFUQ01CEKZ5 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 846 88.02 191/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CAKVYTGAWGDPNFDS# out-of-frame + ctctggattcagctttagcaactttgccatgacttgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtacttttagcacccattatgccgactccgtgaagggccgcttcaccatctccagagacaatttcaggagcaccttatatctgcagatgaacaacctgagagccgacgacacggccatatattactgtgcgaaagtgtacaccggtgcctggggggatcctaattttgactcctgggccagggaaccctggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 22204 JY8QFUQ01CBUHY unproductive Homsap IGHV3-53*04 F 791 85.58 184/215 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 7 X 8.7.X [1.17.38.11] CARQTAPLWG#FDLW out-of-frame + ctcgggggttcaccgtccaaaacagcttcatgagttgggtccgccaggctccagggaagggcctagagtgggtctcagttgtttatagtggtggatccacatactacgcagactccgtgaagggccgtttcaccatcgccagacacagtcgcaacaacattctgtatcttcaaatgaacagcctgagacctgaggacacggctgtttacttctgtgcgagacagactgcccccctttggggaactttgacttatggggccagggaaccctggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccga 22205 JY8QFUQ01BNV04 unknown (see comment) Homsap IGHV3-74*03 F 120 54.55 72/132 nt 8 8 X 8.8.X [1.17.10.X] null + No rearrangement found stop codons tctggattcaccttcagtagctactggatgcactgggtccgccaagctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 22206 JY8QFUQ01ASJB1 unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 959 89.45 212/237 nt 87.76 208/237 nt Homsap IGHJ3*02 F (see comment) 133 74.0 37/50 nt Homsap IGHD2-2*01 F 3 8 7 X 8.7.X [9.17.38.11] CASSVFSPGGFNY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 55 of V-REGION: 'GT' (2 nucleotides at position 102 to 103 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 148 to 148 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 82 of V-REGION: 'G' (1 nucleotides at position 173 to 173 in the user submitted sequence), (cause frameshift); tctctgaagatctcctgtgcagtttcggggttcaccgtcagtagcaagtacatnacctgggtccgccaggctccggggaaggggActggagtctgtctctgGTttttttatagcggtgatcaaacatactacgcagactccgtgaggGggccgattcaccatctccatagacGaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttaactactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 22207 JY8QFUQ01B288U No results 22208 JY8QFUQ01BP7KB unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1086 99.55 219/220 nt 99.09 218/220 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHCISTSCYWGD##YYYGMDVW out-of-frame + in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); agcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggGAagggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattggggagattcactactactacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatnggtcttcccccgtggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact 22209 JY8QFUQ01B0MI7 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 972 94.47 205/217 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD6-25*01 F 2 8 8 15 8.8.15 [1.17.38.11] CVRRGMVAGRYDAFDIW in-frame + ctctggattcaccttcagtagttatagcatgaactgggtccgcctggctccagggaaggggctggagtgggtctcggccattagtattactagtagttccacatattacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagacctcactgtttctgcaaatgaacagcctgagagccgaggacacggctctgtattactgtgtgagaagggggatggtagcgggcagatatgatgcttttgatatctggggccgagggactatggtcaccgtctctccagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 22210 JY8QFUQ01CGZFF productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 962 94.42 203/215 nt 93.95 202/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 1 8 8 10 8.8.10 [1.17.37.11] CARGGLEPVDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT, from codon 66 of V-REGION: 1 nucleotides (from position 104 in the user submitted sequence), (cause frameshift) tctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaaggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 22211 JY8QFUQ01AOJGK productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 972 94.47 205/217 nt 94.01 204/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-17*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAGHLLGDPFDYW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); ttctggagacaactttagcagatactggatcggctgggtccgccagatgcccgggaaaggcctggagtggatggggatcatctatcctggtgactctgGacaccagatacagtccgtccttccaaggccaggtcaccatctcagccgacaagtccaccagtaccgcctacctgcagtggagcagtctgaaggtctcggacaccgccacgtattactgtgcgggacatcttctcggtgacccttttgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22212 JY8QFUQ01BD04C productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-22*01 F 2 8 8 17 8.8.17 [1.17.38.11] CAKGLYYYDSSGYRVFDYW in-frame + ctctggattcacctttagcaactttgccatgagctgggtccgccaggctccagggaagggactggagtgggtctcgactattagtcctagtggtggtaccacatattacgcagactccgtgaagggccggttcaccatctccagagacagttccaagaacacgctgtatctgcaaatgaacatcctgagagccgaggacacggccacatattactgtgcgaaaggactatattattatgacagtagtggttatcgggtctttgactactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 22213 JY8QFUQ01CMDQ5 unproductive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 942 92.27 203/220 nt 91.36 201/220 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD4-11*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CAKSGG*CPLETALTT## out-of-frame - stop codons in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'T' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift); agcctctggattcaccGtttagcaactatgccatgagttgggtccgccaggctcaagggaaTggggctggactgggtctcagatattagtaatagtggtggtgacacattctacgcaggctccgtgaagggccgcttcaccatctccagagacaattccaggaacactctatatctgcaaatggacagcctgagagccgaggacacggccgtgtattactgtgcgaaaagtggggggtgatgtccgctcgagaccgcattgactacttgggggccggggaaccctggtctccgtctcctcaccatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 22214 JY8QFUQ01B3DFL productive Homsap IGHV3-30*01 F 900 90.78 197/217 nt Homsap IGHJ4*02 F 240 100.0 48/48 nt Homsap IGHD3-10*02 F 1 8 8 16 8.8.16 [1.17.38.11] CVKNDLSWGTIEHYFDYW in-frame + ctctggattcacgttcaacatttatggtctacactgggtccgccaggctccagggcaagggctagagtgggtggcacacatatcatatgatggaaataagaaatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgacagctgaagacacggctatttattactgtgtgaaaaatgacctgtcttggggcacaatagagcactactttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22215 JY8QFUQ01CK61T productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 8 13 8.8.13 [1.17.38.11] CAKDQYGSPSDFDNW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 57 of V-REGION: 'GGA' (3 nucleotides at position 84 to 86 in the user submitted sequence), (do not cause frameshift); cctctggtttcacatttagtacgtactggatgagttgggtccgccaggctcccggaaaggggctggagtgggtctcggctattGGAggtgttgatgatgttggcacatactacgcagcctccgtgaagggtcggttcaccatatccagagacgattccagggagattctctatctacaaatgagtaacctgagagtcgacgatacggccgtctattactgtgcgaaagatcaatatgggagcccatccgactttgacaactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22216 JY8QFUQ01C39T0 productive Homsap IGHV3-7*01 F 927 92.17 200/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [1.17.38.11] CVRGRDGVNFGEMDYW in-frame + ctctgggttcatctttagtagacattggatggcctgggtccgccaggctccagggaagaggctggagtgggtggccaacataaaacaagatggaagtctgagatactttgtggactctgtgaagggccgattcaccatctccagagacaacgccgagagctcactgtttctgcaaatggacagcctgagaggcgaggacacggctgtgtattactgtgtgaggggtagagatggtgtcaattttggcgaaatggactactggggccagggaatcctggtcagcgtctcctcggcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22217 JY8QFUQ01B7PA7 unknown (see comment) Homsap IGHV3-9*01 F, or Homsap IGHV3-9*03 F (see comment) 289 66.44 97/146 nt 8 8 X 8.8.X [2.17.13.X] null + No rearrangement found Low V-REGION identity (66,44% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcaggtttgatgattatgccatgcactgggtccggcaagctccagggaagggcctggagtgggtctcaagtatcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 22218 JY8QFUQ01AKF8Q productive Homsap IGHV3-7*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD5-18*01 F 3 8 8 15 8.8.15 [2.17.38.11] CARVGYGYRGIYFFDYW in-frame - gcctctacattcacgtttagtcggtattggatgagctgggtccgccaggctccagggaagggcctggagtgggtggccaacataaaggaagacggaagtgagagatattatgtggactctgtgaagggccgattcaccatctccagagacaatgccaagaactctctgtatctgcaattgaacagcttgagagccgaggacacggctgtgtattactgtgcgagagtgggctatggttaccgaggaatatacttctttgactactggggccagggaatcctggtcaccgtctcctcagcctccacccaaggggccccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22219 JY8QFUQ01AIAM0 productive Homsap IGHV4-4*07 F 823 87.04 188/216 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD6-25*01 F 1 8 7 15 8.7.15 [2.17.38.11] CARQRGGGDRQWAFENW in-frame - gtctctggtacctccatcagcacttactattggagttggttccggcagcccgccgagaagggactggagtggattgggcgtatctctgtctttgaaaactctaactacaacccctccctcgagagtcgcatcaccatgtcaatggacacgtccaagaaccagttctccctgacggtgaactctgtgaccgccgcggacacggccgtgtatttttgtgcgagacaaagaggcggcggcgaccgacagtgggcctttgagaactggggccagggaacccaaatcaccgtctccgcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22220 JY8QFUQ01BZKTI unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 29 of V-REGION: 'G' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 66 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift); ctccggattcGacctttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaAactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 22221 JY8QFUQ01CN5XU productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 851 88.07 192/218 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [1.17.38.11] CAKDRTLHTPAQMSYYGMDVW in-frame + catctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccgtatattactgtgcaaaagaccggacacttcacacacccgctcagatgtcttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccgag 22222 JY8QFUQ01CLR99 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 948 93.93 201/214 nt 93.46 200/214 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [1.17.38.11] CAKEGNLGYFDDW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 83 in the user submitted sequence), (do not cause frameshift) ctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22223 JY8QFUQ01CS2FC unknown (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 172 57.53 84/146 nt 8 8 X 8.8.X [1.17.14.X] null + No rearrangement found ctctggattcatctttgatgattttggcatgagatgggtccgccaagttccggggaaggggctacagtgggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 22224 JY8QFUQ01ATKM1 productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 882 89.86 195/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + ctccggattcacctttagtagtttctggatgcactgggtccgccaagttccaggggagggactggtgtgggtcgcacggactaatgagtatgggagtatcacaaactacgcggactccgtggagggccgattcaccatctccagagacaacaccaagaacaggctatatctgcaaatgaacagtctgagagccgaggacacggctatttattactgtacaagggacatcggtgggcgctactcctactggggccagggagtcctggtctccgtctcatcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcncatgcctggtccagggcttcttccccca 22225 JY8QFUQ01BRMO4 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ1*01 F 89 63.46 33/52 nt Homsap IGHD5-12*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGPRSRGYGMDV## out-of-frame + in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatTttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagtacctctgggggccacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgncgtgtcgtggcaactcagg 22226 JY8QFUQ01CBGMQ productive (see comment) Homsap IGHV3-48*02 F 959 93.58 204/218 nt 93.12 203/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-16*01 F 3 8 8 13 8.8.13 [1.17.38.11] CARDMIIFGGALDNW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 85 to 85 in the user submitted sequence), (cause frameshift); cctctggattcgccttcagtagttccagcatgaactgggtccgccagggtccagggaaggggctggagtggatttcacacattaGggggtagtagtagtaccacccactacgcagactctgtgaagggccggttcaccatctccagagacaatgccaagaactcactgtatctgcaaatgaacagcctgagagacgaggacacggctgtctattactgtgcgagagatatgattatctttgggggagcccttgacaactggggccagggaaccctggtcaccgtctcctctgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgccctgcctggtccagggcttcttc 22227 JY8QFUQ01CNFBY productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame - cctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22228 JY8QFUQ01B7H6T unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 823 95.53 171/179 nt 8 8 X 8.8.X [1.17.25.X] null + No rearrangement found cctctggattcacctttagaagctatgccatgagctgggtccgccaggttccagggaaggggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatg 22229 JY8QFUQ01BEB1K productive Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F 847 87.67 192/219 nt Homsap IGHJ6*02 F 229 85.48 53/62 nt Homsap IGHD2-2*01 F 3 8 8 19 8.8.19 [2.17.38.11] CAKDRTLHTPAQMFYYGMDVW in-frame - gcatctggattcaccttcagttcttatagtgtaaactgggtccgccaggctccagggaagggcctagagtttgtctcatacattgatagtagtggttctaccatatactacgcagactctgtgaagggccgattcaccatctctagagacaatgcccagaactcactgtttctgcaaatgaacaacctgcgagtcgacgacacggccatatattactgtgcaaaagaccggacacttcacacacccgctcagatgttttactatggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatctccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22230 JY8QFUQ01AMDCR unknown (see comment) Homsap IGHV6-1*01 F, or Homsap IGHV6-1*02 F (see comment) 216 56.57 112/198 nt 10 9 X 10.9.X [2.17.28.X] null - No rearrangement found stop codons Low V-REGION identity (56,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctccgggggacagtgtctctagcaacagtcctgcttgagactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22231 JY8QFUQ01CN9HF productive (see comment) Homsap IGHV4-61*08 F 874 89.04 195/219 nt 87.67 192/219 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD3-16*01 F 2 10 7 10 10.7.10 [1.16.38.11] CTRGGYTYDSPW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'C' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 100 of V-REGION: 'G' (1 nucleotides at position 206 to 206 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 40 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) ctctggtgcctccatcagcagtagtggtcactactggagttgatccggcagcccccagggaagggCactggaattcattggaaaaatctattccaatgggaacgccaactacaacccctccttcaagagtcgagtcaccatttcagtggacacgtccgagaaccagttctccctgagcctgaggtctgtgaccgctgcggacacgGgccctttattactgtacgagggggggatacacttatgacagcccgtggggccaggggattcaggtctccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22232 JY8QFUQ01AH0PS productive (see comment) Homsap IGHV1-3*01 F 848 89.15 189/212 nt 88.21 187/212 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD1-26*01 F 2 8 8 14 8.8.14 [0.16.37.11] CARDGEPLGGDYLDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 51 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 83 of V-REGION: 1 nucleotides (from position 150 in the user submitted sequence), (cause frameshift) tggatataccttcacttattacgctataaattgggtgcgccaggcccccgagaaaggcctgagtggatgggatggatcaaccctggcaacggtaatacaaaatattcacagaagttccaggacagactcacctttaccagggacacatcgcgaacacagtttccatggaactgagtagcctgcgatctggagacacggctgtgtattactgtgcgagagatggggagccactgggaggcgactacttggactactggggccagggaactctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22233 JY8QFUQ01C5H9S productive Homsap IGHV4-39*02 F 938 91.86 203/221 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 10 7 18 10.7.18 [1.17.38.11] CARLLRVYDWYSQRGYFDTW in-frame + Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) tctccgatggctccatcagcactagtaattactactggggctgggtccgccagcccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaaggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgggtgtcgtggaactc 22234 JY8QFUQ01BVAZ6 productive Homsap IGHV4-61*02 F (see comment) 794 84.62 187/221 nt Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD4-17*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARAKDHDDYLVDPW in-frame + Low V-REGION identity (84,62% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctctggtgcctccatcactagtggtacttactactggagttggttccggcagcccgccgggaagacactggaatgggttgggcgtatctatacaactgggagcacctattacaacccctctctcaaaagccgagtcaccgtttcagtcgacgagtcccagaatcagctcttcctggacctgacttctgtgaccgccgcggacacggccgtctacttctgtgcgcgagctaaggaccacgatgactacctggtcgacccctggggccaggggatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 22235 JY8QFUQ01A64UI unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 967 94.44 204/216 nt 93.52 202/216 nt Homsap IGHJ4*03 F (see comment) 20 61.54 8/13 nt 8 7 X 8.7.X [1.17.38.X] null + Rearranged sequence but no junction found The JUNCTION has not been identified: the results for J-GENE may be unreliable. in FR2-IMGT at codon 47 of V-REGION: 'A' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 58 of V-REGION: 2 nucleotides (from position 87 in the user submitted sequence), (cause frameshift) cctctggattcacctttagcagccatcccatgagctgggtccgccaggctccgggAaaaagggctggagtggatctcagcttttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaagcatccccgaccagccccaaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22236 JY8QFUQ01CY31M productive (see comment) Homsap IGHV3-9*01 F 802 85.39 187/219 nt 84.47 185/219 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-9*01 F 2 8 8 16 8.8.16 [2.17.38.11] CVKDLSGRPKDMHGMDVW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 56 of V-REGION: 'C' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); gcctctgggttcaggtttagcaattatgccatgcactgggtccgtcaagctccagggaaAgggcctgcaatgggtctcacgtaCttaattggaacagtggaaacatagcctatgcggcctctgtgaggggccgattcaccgtctccagagacgacgccgagcactccctgtatttacaaatgaatggtctgacaactgaagacacggccttatactattgtgtgaaagatttgtctggccgaccaaaggacatgcacggcatggacgtctggggccaagggaccacggtcaccgtcgcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22237 JY8QFUQ01A8GGU productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt 93.09 202/217 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.16.38.11] CAKVVWSLWYFDLW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 48 of V-REGION: 1 nucleotides (from position 59 in the user submitted sequence), (cause frameshift) cgtctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaagggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22238 JY8QFUQ01BAK4Q No results 22239 JY8QFUQ01BH5VO No results 22240 JY8QFUQ01CJPO4 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 961 94.84 202/213 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [X.17.38.11] CARGPRSRGYGMDVW in-frame + ggattcacctttagcagctatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggcaactcag 22241 JY8QFUQ01AKNWR productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 784 84.47 185/219 nt Homsap IGHJ6*02 F 193 79.03 49/62 nt Homsap IGHD6-6*01 F 1 8 8 17 8.8.17 [2.17.38.11] CARDSGSSDYTRYDAQDVW in-frame - Low V-REGION identity (84,47% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctgctggattagttttagttcttatgggcatgaactgggtccgccaggctccagggggggggctggagtgggtctcattcattaacagtgttagtagttacaaatactatgtggacccagtgaggggccgattcaccatctccagagacaacgccaagaacgcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtttactactgtgcgagagatagcggctcgtccgactacactaggtacgacgcccaggacgtctggggccaagggaccgcggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22242 JY8QFUQ01A7IRE No results 22243 JY8QFUQ01AU6BC unproductive (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*12 F (see comment) 706 81.02 175/216 nt 80.09 173/216 nt Homsap IGHJ2*01 F 229 92.45 49/53 nt Homsap IGHD3-3*01 F 3 8 7 X 8.7.X [2.17.38.11] CARAYTFFTF*EWPH#WYSDLW out-of-frame + stop codons Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift); gtctctgatgggtcgttcatgggttacctctggaattggatccgccagcccccagggaaGggggctggagtggattgGgggaaatcagtcctagcggcgtcagtaagtacaatacgtccctcaagagtcgcgttgttatgagaatggacacgtcgaagaagcaattctccctggagatcaactctgtgaccgccgcggacacggctacttattattgtgcgagagcctatacttttttcactttttaggagtggcctcacactggtactccgatctctggggccgtggcaccctggtcacagtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtgcagggcttcttccccca 22244 JY8QFUQ01C4W37 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 953 93.52 202/216 nt 92.59 200/216 nt Homsap IGHJ6*02 F 265 91.94 57/62 nt Homsap IGHD1-20*01 F 1 8 8 19 8.8.19 [1.17.38.11] CANASPRITGTYFYYYGMDVW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'T' (1 nucleotides at position 11 to 11 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); tctggattcaTcgttcagtagcGtatgccatgaattgggtccgccagactccagggaaggggctggagtgggtctcagccattagtggtantggtggtaacacatactacgcagactccgtgaagggccggttcaccgtctccagagacaattccaacaacacgctgtatctgcaattggacagcctgcgagccgaggacacggccgtatattactgtgcgaatgcctccccccgtataactggaacgtatttctactactacggtatggacgtctggggccaagggaccacggtcagcgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22245 JY8QFUQ01BQMPO No results 22246 JY8QFUQ01A4UI3 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 938 91.86 203/221 nt 90.95 201/221 nt Homsap IGHJ6*02 F (see comment) 256 90.32 56/62 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [2.17.38.11] CAHGPSAAPHYYYYYGLEAW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 28 of V-REGION: 'T' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in CDR1-IMGT at codon 38 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift); aggcctctggattTcacctttaccaactatgGgcatgaggtgggtccgccaggctccagggaaggggctggagtgggtctcagatattagcgctggtggcgataacacatactacgcagactccgtgaagggccggttcaccatctccagagacaatttcaggaacacgctgtatctgcaaatgagcagcctgagagccgaggacacggccctttattactgtgcgcatgggcccagtgcagcaccccattactactactattacggtttggaagcttggggccaagggaccaaggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22247 JY8QFUQ01BGDEX productive (see comment) Homsap IGHV3-7*01 F (see comment) 743 82.57 180/218 nt 82.11 179/218 nt Homsap IGHJ2*01 F 238 94.34 50/53 nt Homsap IGHD2-15*01 F 1 8 8 15 8.8.15 [1.17.38.11] CARLKGLTHHDFYFDLW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (82,57% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); cctctggattcgtctttactaatcattggatgagttgggtccgccaggccacagggaaggggccggagtgggtggccaacatatccccagacggaaatacgaaatattttggggactctgtgaGggggccgattcagcgtctccagagacaacggcaagcagtcatcgtatctggaaatgaataccctgacagtcgatgacacggctgtatacttctgtgcgaggttgaaggggctgacacatcacgacttctacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacacgcgggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaact 22248 JY8QFUQ01A1FF8 No results 22249 JY8QFUQ01BK0SF unknown (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 968 92.07 209/227 nt 90.31 205/227 nt 8 7 X 8.7.X [5.17.38.X] null + No rearrangement found in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 49 to 49 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 73 to 73 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); cagcctctgcagcctctggattcattgtcaatagcaactacatgagttGgggtccgccagGgctccagggaaGggggctggactgcgtctcagttatttatcccggtgGgtagcacatactatgcagactccgtgaagggccgattcaccatctccagagacatctccaagaacacactgtatcttcaaatgaacagcctgagagccgaggacacggctgtatattactgtgcgagaggggccccattttcatgatagtgttaaggggaacccctggtcaccgtgctcttcagcctccaccaag 22250 JY8QFUQ01CMTEA unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 847 87.67 192/219 nt 87.21 191/219 nt Homsap IGHJ4*02 F, or Homsap IGHJ4*03 F 87 64.58 31/48 nt Homsap IGHD6-19*01 F 2 8 8 X 8.8.X [2.17.38.11] CAGSGRDPYGINV## out-of-frame + in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggattcaccttcaattcctataccatgatgtgggtccgccaggctccggGggaagggactggagtgggtctcaaccattagtcctagtagtcagtacatatactatgcagactctgtggagggccgattcaccatctccagagtcgacgcccggagttcagtgtttctgcaaatgaacagcctgagagacgacgacacggctgtgtattactgtgcgggcagtggcagggatccgtacggtattaacgtctggggccaaggggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttccccca 22251 JY8QFUQ01BCF8N unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 476 70.24 144/205 nt 8 8 X 8.8.X [1.17.34.X] null + No rearrangement found Low V-REGION identity (70,24% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release tctggattcatcttcagtagctactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtgtcacgtagtaatacgggggggactgacacagcctacgcggactccgtgaagggccgattcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 22252 JY8QFUQ01A8PYD unproductive Homsap IGHV3-9*01 F 887 89.91 196/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 79 62.0 31/50 nt Homsap IGHD1-1*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKDVTSESHFFALDV## out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) cctcgggattcaagtttgatgaatatgccatgcactgggtccggcgagttccagggaggggcctggagtgggtctcagttataagttgggatggtgatgacatcgcctatgcggactctgtgaagggccgattcagcatctccagagacaacgccaagaactccctgtacctggaaatgagcagtctgagagttgaggacacggccttctattactgtgcaaaggatgtcacatctgaaagtcacttcttcgctttggacgtctgggggccaagggaccgcggtcaacgtctctccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22253 JY8QFUQ01CFYV1 productive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1057 99.07 214/216 nt 98.61 213/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-10*01 F 2 8 7 11 8.7.11 [2.17.38.11] CARLGPGSGTDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 50 to 50 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagtagttcctactggagctggatccggcagcCccccagggaagggactggagtggattgggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactggggcccggttcggggactgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggtcctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22254 JY8QFUQ01BZRQM productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 938 91.86 203/221 nt 91.4 202/221 nt Homsap IGHJ5*02 F 183 84.31 43/51 nt Homsap IGHD3-10*01 F 2 10 7 16 10.7.16 [1.17.38.11] CVRPDNYFGSGSAWMDPW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtgataatttctactggggctggatccgccagcCccccagggaagggactgcagtggattgggactttctattatagagggagtatctattacaacccgtccctcaagagtcgagtcaccatatccgtggacacatccaagaaccagttctccctgaggctgacctctgtgaccgccgcagacacggctgtctattattgtgtgagacccgataattactttggttcggggagtgcctggatggacccctggggccacggaaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22255 JY8QFUQ01AQ0AZ unproductive Homsap IGHV3-7*01 F 923 91.74 200/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD3-3*02 F 3 8 8 X 8.8.X [1.17.38.11] CARGSYWHYDTFGDY## out-of-frame + in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggatttacttttaacaactattggatgacctgggttcgccaggctccagggaaggGggctggaatgggtggccaacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcagtgtatctgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgagagggtcgtattggcattatgataccttcggcgactattgggggcccgggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtgggcaactca 22256 JY8QFUQ01APPTA unproductive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 831 87.85 188/214 nt 87.38 187/214 nt Homsap IGHJ4*01 F, or Homsap IGHJ4*03 F 69 60.42 29/48 nt Homsap IGHD3-10*01 F 1 8 7 X 8.7.X [1.17.38.11] CAREKGSGPPHRA#DVW out-of-frame - in FR3-IMGT at codon 93 of V-REGION: 'G' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift); ctctgggttgaccgtcagtgccgaccacatgtactgggtccgccaggctccagggaaggggctggagtgggtctcagttctttatggcggtggcaccttggactacgcagactccgtgaagggccgattcaccatctccagagacaattcgaggaacactgtgtatcttcagatggacGagactgagccccgaggacacggccgtctactactgtgcgagagaaaaaggttcgggccccccccacagggcatggacgtctggggcccagggaccatggtcacccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctccctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22257 JY8QFUQ01DMHUQ productive (see comment) Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 936 92.63 201/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVRAGFGELSGFDCW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 50 of V-REGION: 'GC' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'AG' (2 nucleotides at position 76 to 77 in the user submitted sequence), (cause frameshift); ctctggattcacctttggttattatggcatgagctgggtccgccaagctccgggggaggggGCtgggagtgggtcAGtctggtattaatcggaatggtgatagcacaggttatgcagactctgtgcaggaccgattcaccatctccagagacaacgccaagaactccctgtatctcgaaatgttcagtctgacagccgaggacacggccttatatcactgtgtgagagcagggttcggggagttatcgggctttgactgctggggccagggaaccctggtcaccgtgtcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctggggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22258 JY8QFUQ01A5NTK unknown (see comment) Homsap IGHV1-NL1*01 P 85 56.25 45/80 nt 1 X X 1.X.X [25.X.X.X] null - No rearrangement found agttccacgacaccgtcaccggttcggggaagtagtccttgaccaggcagcccagggccgctgtgccccagaggtgctcttggaggagggtgccagggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 22259 JY8QFUQ01CUTV1 productive Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 858 89.25 191/214 nt Homsap IGHJ1*01 F 224 92.31 48/52 nt Homsap IGHD3-10*01 F 2 8 7 14 8.7.14 [1.17.38.11] CASGGYSGSGEYFLRW in-frame + ctctgacttaagcgtcagtgacaattacatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaattatgtatagcggaggtcgcacatactacgcagagtccgtgaagggccgattcgccgtctccagagacaattcccagaatacactgtatcttcaaatgaacagcctgaggaccgaagacacggccgtgtactattgtgcgagtggtggttattcgggctcgggtgaatacttcctacgctggggccagggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22260 JY8QFUQ01BHIXV unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt 99.1 219/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagcagtGagtagttactactGggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22261 JY8QFUQ01BAP2B productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 855 88.48 192/217 nt 88.02 191/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.16.38.11] CVKGWNYHSATFGFDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 47 of V-REGION: 1 nucleotides (from position 55 in the user submitted sequence), (cause frameshift) cctctggattcacctttagtgactatgccataagctgggtccgccaggctccagaaaggggctggagtgggtctcctctattagtgctactggtggaattacatcttacgcagattccgtgaagggccggttcaccattttcagagacaactccaaagacacgctgtatctgcaaatgggcagcctgagagacgaggacacggccatttattactgtgtgaagggttggaattaccatagtgcaacctttgggtttgactactggggccagggaaccctggtcaccgtctcctcacatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22262 JY8QFUQ01B31RJ productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 881 90.23 194/215 nt 89.3 192/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD4-23*01 ORF 3 8 7 12 8.7.12 [1.17.38.11] CASSVFSPGGFDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 39 of V-REGION: 'T' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 92 to 92 in the user submitted sequence), (cause frameshift); tttcggggttcaccgtcagtagcaagtacatTgacctgggtccgccaggctccggggaagggactggagtctgtctctgttttttatagcgGgtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatcttcaaatgaacggcctgcgagccgaggacacggccgtgtattattgtgcgagctccgtgtttagtcccggaggctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22263 JY8QFUQ01AGCNW unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 523 70.78 155/219 nt 8 8 X 8.8.X [2.17.38.X] null + No rearrangement found Low V-REGION identity (70,78% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctctggattcacctttaccaactacgccatgagctgggttcgccaggttccagggaaggggctggagtgggtctcacttattagtgttcgtggcgatgacaccttctatgcagactccgtgaagggccggttcaccatctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22264 JY8QFUQ01C4VM3 unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1095 100.0 220/220 nt 99.55 219/220 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-18*01 F 2 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANYW# out-of-frame - in CDR1-IMGT at codon 35 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtGagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccaggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22265 JY8QFUQ01BG27O productive (see comment) Homsap IGHV3-48*03 F 850 88.43 191/216 nt 87.96 190/216 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.16.38.11] CARDKGWSGYGMDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 42 of V-REGION: 1 nucleotides (from position 40 in the user submitted sequence), (cause frameshift) ctctggattcaccttcagttcttatgccatgaactgggtcgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22266 JY8QFUQ01ALIXE unproductive Homsap IGHV3-11*06 F (see comment) 760 83.8 181/216 nt 82.87 179/216 nt Homsap IGHJ1*01 F 125 71.15 37/52 nt Homsap IGHD5-12*01 F 1 8 7 X 8.7.X [2.17.38.11] CSRDGRRGYDLDS## out-of-frame - The submitted sequence and the closest germline V-GENE allele show different CDR2-IMGT amino acid lengths (7 AA in JY8QFUQ01ALIXE ; 8 AA in Homsap_IGHV3-11*06), and low V-REGION identity (83,80% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 36 of V-REGION: 'AC' (2 nucleotides at position 24 to 25 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); gcctctggattcacctttcgggaACctatgccatgacgtgggtccgcctgactcctgggaAaagggctggagtgggtttcatggattagtgatatcggtgacacacgctatgcagattctgtgaagggccgattcaccatctccagagacaatgccaagaattcactgtttctgcaaatggacagtctcagagccgacgacacggctatatattattgttcgagagatggccggaggggctacgaccttgactcctgggggccagggagccctggtcaccgtctcctcatcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 22267 JY8QFUQ01A4VB0 productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 866 88.24 195/221 nt 87.78 194/221 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD3-22*01 F 2 10 7 13 10.7.13 [1.17.38.11] CARQLSGDYASFDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 64 to 64 in the user submitted sequence), (cause frameshift); tctctggtgcctccatcaccagtggtactttttactgggcctggatccgccagcccccagggaAaggggctggagtgggttggcaatatctattctagtggtgtcgcctattacaacccgtccctcaagagtcgagtcaccatgtccgtcgacacgtccaagaatgagttttccctgacactgacctctgtgaccgccgcagacacggctgtatatttctgtgcgagacagctcagtggtgactacgcatcgtttgactcctggggccagggaaccctggtcgccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22268 JY8QFUQ01CR4ZL productive Homsap IGHV3-48*03 F 855 88.48 192/217 nt Homsap IGHJ6*02 F 211 82.26 51/62 nt Homsap IGHD3-3*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARDKGWSGYGMDVW in-frame + ctctggattcaccttcagttcttatgccatgaactgggtccgcctggttccaggcaaggggctggaatggctttcatttattggtaatactggtagtgtcatatactacgcagactctgtgaaggggcgattcaccatctccagagacaatgccaagaactcaatgtctctacaaatgagcagcctgagagccgaggacacggctctatattattgtgcgagagataaaggttggagcggatacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22269 JY8QFUQ01BYM2X No results 22270 JY8QFUQ01CHX5X unproductive Homsap IGHV4-39*02 F 933 91.82 202/220 nt 90.91 200/220 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 2 10 7 X 10.7.X [1.17.38.11] CARLLRVYDWYSQRGLL#DTW out-of-frame - Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift); ctccgatggctccatcagcactagtaattactactgGgggctgggtccgccagGcccccagggaaggggctggagtggattggaagtatatattatagtgggagcaccgactacagctcgtccctcaggagtcgcgtcaccatatccagagacacgtccaagaaccacttctccctgaaggtgacctctgtgaccgccgcagacacggctatatattactgtgcgagactcttacgggtttatgactggtacagtcaaagggggttacttcgacacctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22271 JY8QFUQ01C5DZY unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F 371 88.3 83/94 nt 87.23 82/94 nt 8 3 X 8.3.X [2.17.X.X] null + No rearrangement found in FR2-IMGT at codon 50 of V-REGION: 'A' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); aagcctctaaattcacttttagtaactattggatgaattgggtccgccaggctccagcgaaggggActggagtgggtggccagtataaagcagga 22272 JY8QFUQ01ALVU9 productive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 796 85.65 185/216 nt Homsap IGHJ6*02 F (see comment) 193 79.03 49/62 nt Homsap IGHD6-19*01 F 1 8 8 17 8.8.17 [1.17.38.11] CVRDSDSSGYARYDSMDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcaacctcaatacctttggcatgaactgggtccgccaggcgccagggaagggactggagtgggtctcacacgtcaatcggggtagtactcacatatactacgcaggctcagtgaggggccggttcaccatctccagagacgacgccgggaactcagtctatctgcaaatgaatagcctgagagccgaggacacgggtttatattattgtgtgagagacagtgactcgtccggctacgcgaggtacgactctatggacgtctggggccaagggaccgcggtcaccgtctcatcagcctccagccaaggccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 22273 JY8QFUQ01B70VI unproductive Homsap IGHV3-7*01 F, or Homsap IGHV3-7*02 F 610 96.21 127/132 nt 95.45 126/132 nt Homsap IGHJ4*03 F (see comment) 150 79.17 38/48 nt Homsap IGHD2-8*01 F 1 8 X X 8.X.X [2.3.31.11] CVRDVSLYSNDGYDAF#YW out-of-frame + Other possibilities: Homsap_IGHJ3*01 (highest number of consecutive identical nucleotides) in FR2-IMGT, from codon 42 of V-REGION: 87 nucleotides (from position 40 in the user submitted sequence), (do not cause frameshift) gcctctggattcatttttagtaacttttggatgagttggggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgtgagagacgtctccctttatagtaatgatggatatgatgcttttgatattggggccaggggacagtggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22274 JY8QFUQ01A378B No results 22275 JY8QFUQ01CGATX unproductive (see comment) Homsap IGHV3-48*01 F 932 92.2 201/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD1-26*01 F 3 8 8 X 8.8.X [1.17.38.11] CARDGGTLRY##DYW out-of-frame + stop codons cctctggattcaccttcactagaagtcccatgaattgggtccgccaggctccggggaaggggctggaatgggttgcatacattagtagtgatggtagtaccctatactacgcagactctgtgaagggccgattcaccatctccagagacaatgccaaagacttactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagacggggggactctacggtactcttgactattggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccctaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccc 22276 JY8QFUQ01DJPRS No results 22277 JY8QFUQ01BMPOE No results 22278 JY8QFUQ01BVA9L productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 887 89.91 196/218 nt 88.99 194/218 nt Homsap IGHJ3*01 F 178 84.0 42/50 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKEQRGSGWSRSALDVW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 59 to 59 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 128 to 128 in the user submitted sequence), (cause frameshift); cctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaGggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaaggGgccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaacgaggcagtggctggtcccgatcggctcttgatgtctggggccaaggggcatgggtcaccgtctcttcagcctccaccaaggggcccatcggtcttcccccctggcgccctgctcccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22279 JY8QFUQ01CORXQ unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 915 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD6-19*01 F 3 10 7 X 10.7.X [1.17.38.11] CARQSFISRGSGR*I#YFEYW out-of-frame - stop codons in CDR1-IMGT at codon 34 of V-REGION: 'G' (1 nucleotides at position 23 to 23 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 58 of V-REGION: 'C' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift); ctcctggtggctccgtcagcagGtagcacttactactggggctggctccgccagtccccagggaaggctctggantggattgggactatccatcaCtagtgggagcacctaccagaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaggaaccagttctccctgaggctgagctctgtgaccgccgcagacacggctctttattactgtgcgagacaaagctttatttcgcgtggcagtggcaggtagattattactttgaatactggggcctgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22280 JY8QFUQ01AOWYJ productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F (see comment) 748 82.19 180/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKDDSAGLDHW in-frame - Low V-REGION identity (82,19% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcctccggattcatcttcagtgccgcttggatggagtgggtccgccaagttccagggcaggggctcgtgtgggtcgcgcgtatcgagagtagtggcagcggcacactttacgcggactacgtgaagggccgattcaccgtctccagagacaacgccatgaacatagtgtatcttcaaatgaattctctgactgccgaggacacgggtgtgtattactgcgcaaaggatgattcggccggccttgaccattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22281 JY8QFUQ01BXMZP unknown (see comment) Homsap IGHV4-61*02 F 879 88.69 196/221 nt 10 7 X 10.7.X [1.17.38.X] null - No rearrangement found tctctggtgactccatcagtagtgattctcactactggagttggatccggcagcccgccgggaagggactggagtggattgggcgtgtctacgccagtgggaccaccaattacagcccctccctcaagagtcgagtcaccatttcagtggacacgtccaggaatcaattctccctgaagttgaattctgtgaccgccgctgacacggccgtttatttntgtgcgagagatttttggaggttcctacaattttagtggcctactgggggccaggggaaccctgggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22282 JY8QFUQ01CVWQE No results 22283 JY8QFUQ01AGKMG productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1017 96.77 210/217 nt 95.85 208/217 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD1-1*01 F 3 8 8 8 8.8.8 [2.17.37.11] CAVNWNLDSW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in FR3-IMGT, from codon 75 of V-REGION: 1 nucleotides (from position 132 in the user submitted sequence), (cause frameshift)in FR3-IMGT, from codon 84 of V-REGION: 1 nucleotides (from position 156 in the user submitted sequence), (cause frameshift) gcctctggattcacctttagcggctatgccatgagctgggtccgccaggctccagggaaggggctggactgggtctcatctattagttataatggtggtagcacatactacgcagactccgtgaagggccgttcaccatctccagagacaattccagaacacgctgtatctccaaatgaacagcctgagagccgaggacacggccgtatattactgtgctgtgaactggaaccttgactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22284 JY8QFUQ01BZPUF productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 922 92.13 199/216 nt 90.74 196/216 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [1.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 122 to 122 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); tctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaagGgggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgCaggggccggttcaccatctccagagacaacTcccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22285 JY8QFUQ01AKWRH unknown (see comment) Homsap IGHV3-69-1*01 P, or Homsap IGHV3-69-1*02 P 136 52.36 100/191 nt 8 8 X 8.8.X [1.17.30.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccagggaaggggctggagtgggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22286 JY8QFUQ01DC7HF unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 1043 98.6 212/215 nt 96.28 207/215 nt Homsap IGHJ5*02 F (see comment) 120 70.59 36/51 nt Homsap IGHD3-10*01 F 3 8 7 X 8.7.X [1.17.38.11] CARLGARFGD*LL# out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 32 to 32 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 41 of V-REGION: 'G' (1 nucleotides at position 38 to 38 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'TAG' (3 nucleotides at position 56 to 58 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'GC' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 83 to 83 in the user submitted sequence), (cause frameshift); tctctggtggctccatcagtagttcctactgGgagctGggatccggcagccccccTAGgggaagggGCactggagtggattgGggtatatctattacagtgggagcaccaactacaacccctccctcaagagtcgagtcaccatatcagtagacacgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtgtattactgtgcgagactgggggcccggttcggggactgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaccggtgacggtgtcgtggaactc 22287 JY8QFUQ01DD5Q8 unproductive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F or Homsap IGHV3-15*04 F 1007 94.64 212/224 nt Homsap IGHJ1*01 F (see comment) 161 78.85 41/52 nt Homsap IGHD1-26*01 F 3 8 10 X 8.10.X [1.17.38.11] CTTGGWN*L##W out-of-frame - stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcactttcagtgacgcctggatgagctgggtccgccaggctccagggaaagggctggagtgggttggccgtattccaagcaaagctgatggtgggacaacagactacgctgcgcccgttaaaggcagattcaccatctcaagagaggattcaaaaaatatgctgtatctgcaattgaacagcctgaaaaccgaggacacagccgtgtatttctgtaccacaggggggtggaactaactactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22288 JY8QFUQ01CK636 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 818 86.98 187/215 nt 86.51 186/215 nt Homsap IGHJ4*02 F (see comment) 204 91.67 44/48 nt Homsap IGHD3-10*02 F 2 8 7 X 8.7.X [1.17.38.11] CAKESLFGESS#YYFDDW out-of-frame + Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) in CDR2-IMGT, from codon 58 of V-REGION: 3 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) cctctggattcaactttggcatctataccatggcctgggtccgccaggctccagggaaggggctggagtgggtctcagctattcgtgatcatgatagcacatactacgcagactccgtgcagggccggtttttcatctcgagagacaatttcaataatacattgtatctgcaaatggatggcctgcgagccgacgacacggccgtctattactgtgcgaaagagtctctgttcggggagtcatctcatactactttgatgactggggccaggggaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22289 JY8QFUQ01AV9WM productive (see comment) Homsap IGHV3-66*02 F 957 94.39 202/214 nt 92.99 199/214 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD4-17*01 F 3 8 7 11 8.7.11 [1.17.38.11] CARGGRGLRMTTG in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 36 of V-REGION: 'G' (1 nucleotides at position 21 to 21 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 123 to 123 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 97 of V-REGION: 'C' (1 nucleotides at position 193 to 193 in the user submitted sequence), (cause frameshift); ctctggattcaccgtcaataGgaaactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagGggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagaggtCgacgacacggctgtgtattactgtgcgagagggggacgggggttaaggatgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22290 JY8QFUQ01A8VKJ No results 22291 JY8QFUQ01CDQVB productive (see comment) Homsap IGHV2-5*02 F, or Homsap IGHV2-5*05 F or Homsap IGHV2-5*06 F or Homsap IGHV2-5*09 F 909 86.07 210/244 nt 84.84 207/244 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-11*01 ORF 1 10 7 11 10.7.11 [9.16.38.11] CAHFGPQEHFDFW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 35 of V-REGION: 'A' (1 nucleotides at position 48 to 48 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 95 of V-REGION: 'GG' (2 nucleotides at position 216 to 217 in the user submitted sequence), (cause frameshift); in FR2-IMGT, from codon 50 of V-REGION: 1 nucleotides (from position 94 in the user submitted sequence), (cause frameshift) agactctcaccctgacctgcgacttctctggattctcactcagcacaAaatggtatggctgtgggctggatccgccagcccccgggagaggcccggagtggctcgcacacatttattgggatgatgatcggcgataccggccatccctagagaggaggctcaccatcaccaaggacatctccacaagcaaggtggtccttacaatgaccgacatgGGgcccctgcagacacagccacatacttctgtgcacactttggaccacaagaacacttcgacttttggggccagggaatcctggtcactgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccag 22292 JY8QFUQ01DOLOU productive Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F or Homsap IGHV4-34*07 F 840 88.32 189/214 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-13*01 F 2 8 7 8 8.7.8 [1.17.38.11] CARISAFDQW in-frame + acacggcgggtccttcaaaggttactattggagctggatccgccagcccccaggaaaggggctggagtggattggagaaatcgaccatagtggaaacaccaactacaacccgtccctcaagagtcgagtcaccgtgacagttgacacatccaagaaccaaatttccctgaatttgacctctgtgaccgccgcggacacggctatttattactgtgcgcgtatttcagcctttgaccagtggggccagggaaccccggtcaccgtctcctcagcatcccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccg 22293 JY8QFUQ01A5LZ5 No results 22294 JY8QFUQ01CAJR1 productive Homsap IGHV3-48*01 F 964 93.61 205/219 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD2-21*02 F 3 8 8 9 8.8.9 [2.17.38.11] CARDQVTEDYW in-frame + gcctctggtttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaaggggctggagtgggtttcatacattagcagtagtactactaccaaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactggggccagggaaccctggtcagtgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22295 JY8QFUQ01BWLHZ productive Homsap IGHV3-20*01 F, or Homsap IGHV3-20*02 ORF 964 93.61 205/219 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD2-8*01 F 3 8 8 10 8.8.10 [2.17.38.11] CAREVSDAFEMW in-frame - gcctctggattcatctttgatgattttggcatgaattgggtccgccaagctccagggaaggggctggagtgggtcgctggtatcagttggaatggtggcaaagcaggtcacgcagactctgtgaagggccgattcaccatctccagagacaacgccaagaactccctgtatctgcaaatgaacagtctgagagccgaggacacggccgtgtatcactgtgcgagagaggtgtctgatgcttttgaaatgtggggtcaagggacaacggtcaatgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22296 JY8QFUQ01BAIZZ unknown (see comment) Homsap IGHV3-7*01 F, or Homsap IGHV3-7*03 F (see comment) 662 77.98 170/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found Low V-REGION identity (77,98% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release cctctggattcagttttagtgacttttggatgcactgggtccgccaggctccagggaaggggctggagtgggtggcccacgtgaaccaagacgggactgagagatactatgccgactctgtgaagggccgcttcaccatctccagagacaacgccaagaaatcactgtttctgcaaatgaatggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca 22297 JY8QFUQ01B5K5P productive (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F (see comment) 793 84.55 186/220 nt 84.09 185/220 nt Homsap IGHJ5*02 F 219 92.16 47/51 nt Homsap IGHD6-13*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARGRIVSVGMSGWFDPW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,55% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 53 of V-REGION: 'A' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift); aatctctggattcactctcagcagttttacactgaattgggtccgccaggctccggggaaggggctggantgggtActcatctataagtagtaccagtacttacaagcattatgctgacacggtggagggccgattcaccatctccagagataacgccaagaactcagtgtatctgcaaatgaacagtctgagagtcgacgacacggctgtatattattgtgcaagaggccgtatagtatcagttgggatgtcaggctggttcgacccctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22298 JY8QFUQ01B1P1F unknown (see comment) Homsap IGHV4-34*01 F, or Homsap IGHV4-34*02 F 719 85.28 168/197 nt 84.77 167/197 nt 8 2 X 8.2.X [1.17.37.X] null + No rearrangement found stop codons in CDR2-IMGT, from codon 58 of V-REGION: 18 nucleotides (from position 87 in the user submitted sequence), (do not cause frameshift) tctgtggtgggtccttcagtggtttctactagagatgcatccgccagcccccagggaaggggctggacaggattgatgaaagcaatcccaggccgtccctcaggagtcgagtcaccagatcactggacacgtccaagaaccaatcctccctgacggtgcattctgtgcccgccgcggactcggctgtatattactttgcgcattggccggaaagtgcttccaccaagggcccatcggtcttcccctggcgccctgctccaggagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcagg 22299 JY8QFUQ01B2K3A unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 963 94.01 204/217 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD3-3*01 F 2 8 8 X 8.8.X [1.17.38.11] CARGWFGAR#DYW out-of-frame - ctctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcccgtatcaatcctgatgggcgaatcacaaactacgcggactccgtgaatggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatgaacagtctgagagccgaggactcggctgtgtactactgtgcaagggggtggtttggagcccgtagattattggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacgtgtcgtggaactcag 22300 JY8QFUQ01APBXM unproductive Homsap IGHV3-9*01 F 848 89.15 189/212 nt 88.68 188/212 nt Homsap IGHJ1*01 F (see comment) 80 61.54 32/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.36.11] CSKDRYHFDSSQHAMDVW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR3-IMGT, from codon 82 of V-REGION: 6 nucleotides (from position 150 in the user submitted sequence), (do not cause frameshift) cctctggattcacctttggtgactttgccatgcactgggtccgacaacctccagggaagggcctggagtgggtcgcgactattagttggaggaatattagtagaggctatgcggactctgtgaagggccgattcaccatctccagagacaagaactccctgtacttgcaaatgaacactctgagatcagaggacacggccttctattattgttcaaaagacaggtatcattttgatagtagtcagcacgctatggacgtctgggggccaagggacccccggtcaccgttttctcagcctccaccaagggcccatcgggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22301 JY8QFUQ01ARBGD unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 860 88.53 193/218 nt 88.07 192/218 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD5-18*01 F 1 8 8 X 8.8.X [1.17.38.11] CAKDSRAGGYPNGYFYYSGLDV## out-of-frame - Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) in CDR2-IMGT at codon 64 of V-REGION: 'G' (1 nucleotides at position 100 to 100 in the user submitted sequence), (cause frameshift); cctctggacgctccttgagaagctttggcatgcactgggtccgccaggctccaggcaagggactggagtgggtggcacttacttcgtatgacggaaataGggaaatattatgcagactccgtgaagggccgattcaccatctccagagacaactccaagaatacgttatttctgcaaatggacagtctgagagctgaggacacggctctttattactgtgcgaaagattcgcgagcgggtggttatccaaatggatacttctattactctggtctggacgtctgggggccaagggacaatagtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22302 JY8QFUQ01B41JB unproductive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 941 92.66 202/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F 114 70.83 34/48 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [1.17.38.11] CTRDIGGRYSY## out-of-frame - in CDR1-IMGT at codon 30 of V-REGION: 'G' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 84 of V-REGION: 'A' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 90 of V-REGION: 'A' (1 nucleotides at position 178 to 178 in the user submitted sequence), (cause frameshift); cctccggattcaccGtttagtagttactggatgcactgggtccgccaaactccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccAaagaacaggctgtatctgcaAaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcggtactcctactgggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgatagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 22303 JY8QFUQ01BOLZD unproductive Homsap IGHV3-30*01 F 864 88.94 193/217 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 1 8 8 X 8.8.X [1.17.38.11] CARGTMLRGSHQSE#YGLDVW out-of-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) ctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcgggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22304 JY8QFUQ01BSXTY unknown (see comment) Homsap IGHV4-61*02 F (see comment) 535 76.06 143/188 nt 75.0 141/188 nt 10 7 X 10.7.X [2.17.26.X] null + No rearrangement found Low V-REGION identity (76,06% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR1-IMGT at codon 35 of V-REGION: 'T' (1 nucleotides at position 27 to 27 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 66 to 66 in the user submitted sequence), (cause frameshift); gtctctggtgactccattaccagtggTtttttactactggaattggatcagacagcccgccgggaGggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaaggtctatcttctgaggttggtctc 22305 JY8QFUQ01CBB8N No results 22306 JY8QFUQ01CA1YJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 936 92.63 201/217 nt Homsap IGHJ4*02 F 141 77.08 37/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + ctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgcagggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggctgtcgtggaact 22307 JY8QFUQ01BB7NQ productive (see comment) Homsap IGHV3-7*01 F 927 92.17 200/217 nt 91.71 199/217 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD3-22*01 F 2 8 8 14 8.8.14 [1.16.38.11] CARGSYYHYDMFGDYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT, from codon 55 of V-REGION: 1 nucleotides (from position 79 in the user submitted sequence), (cause frameshift) cctctggatttacttttagcaactattggatgacctgggttcgccaggctccagggaaggggctggagtgggtggccacataaaacaacatggaggtgaaacgtactatgtggactctgtgaagggccgattcaccatctccagagacaacgccgagacctcactgcatctgcaaatgaacagcctgagagccgaggacacggctgtctattattgtgcgagagggtcgtattatcattatgatatgttcggcgactactggggccagggagtcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22308 JY8QFUQ01BM24H productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*03 F 213 93.75 45/48 nt Homsap IGHD1-26*01 F 1 8 7 11 8.7.11 [2.17.38.11] CAKEGNLGYFDDW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcaccctgtgcagccatcccatgagctgggtccgccaggctccgggaaaagggctggagtggatctcagctttcgttcgtagtggtaacacatactacgtagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaaagaaggtaatctgggctactttgacgactggggtcaggggaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22309 JY8QFUQ01AEQKP unknown (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F or Homsap IGHV3-64*01 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64D*06 F 81 51.11 69/135 nt 8 8 X 8.8.X [1.17.10.X] null - No rearrangement found stop codons cctctggattccccatcagtggctttagaatgaactgggtccgccaggctccaaggtcttcccgttgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22310 JY8QFUQ01BXV9N productive Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 889 89.19 198/222 nt Homsap IGHJ6*02 F (see comment) 166 74.19 46/62 nt Homsap IGHD3-10*01 F 3 8 10 15 8.10.15 [1.17.38.11] CVTGVKASGGAHAMDVW in-frame - Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) tctggattcagtttcagagacgcctggatgaattgggtccgccagtctccagggaaggggctggagtgggttggccgtgttaaaaggaaaactgatggtgggacgtcggaatatgctgcattcgtgaaaggcagattcaccatctcaagagatgattcagaaaacacactgtatctgcaaatgaacagcctggaaatcgacgacacagctgtgtatcgttgtgtcacaggagttaaggcttcggggggggctcacgctatggacgtctggggccaagggaccgcggtcatcgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccc 22311 JY8QFUQ01A74UT productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F or Homsap IGHV4-59*04 F (see comment) 728 82.33 177/215 nt 81.86 176/215 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD3-3*01 F 2 8 7 12 8.7.12 [1.17.38.11] CTRRWSGNYPFDYW in-frame - Potentially, because of detected insertion/deletion The submitted sequence and the closest germline V-GENE allele show different CDR1-IMGT amino acid lengths (8 AA in JY8QFUQ01A74UT ; 10 AA in Homsap_IGHV4-39*01), and low V-REGION identity (82,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 94 to 94 in the user submitted sequence), (cause frameshift); cctctggattcagcttcagtgactactacatgagttgggtccgccagtccccagggaagggactggagtggcttggaaacatctattttaatgGggaacacgtactacaacccgtccctcatgagtcgagtcaccatctccgcagacaagtccagaaaacagttctcactgagactgacctctgtgaccgccgcagactcggctgtgtattattgtacgagacggtggagtggaaattatccatttgactactggggccagggaacgctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22312 JY8QFUQ01DB61A unproductive Homsap IGHV4-39*03 F 907 90.05 199/221 nt 87.78 194/221 nt Homsap IGHJ4*03 F 96 66.67 32/48 nt Homsap IGHD3-22*01 F 2 10 7 X 10.7.X [2.17.38.11] CARSITLTVVVMNDAFDVW# out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'TG' (2 nucleotides at position 38 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 62 to 63 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'TTG' (3 nucleotides at position 76 to 78 in the user submitted sequence), (do not cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'A' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 109 to 109 in the user submitted sequence), (cause frameshift); gtctccggtggctccatcaacagtagaaaattattatTGggggctggatccgccagcccccCAggggaaggggttTTGggagtggattggAaaatatctattatagtgGggaacacctactacaatccgtccctcaagagtcgagtcaccgtatccgtagacaggtctaagaaccagttgtccctgaagctgacctctctgaccgccgcagacacggccgtatattactgtgcgaggagtattactctgacagtagtggttatgaatgatgcttttgatgtctgggggccaaggggacattggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggccacagcggccctggggctgcctggtcaaggactacttcctgcgaaccggtgacggtgtcgt 22313 JY8QFUQ01CNKMG productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 905 90.83 198/218 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD5-12*01 F 3 8 8 10 8.8.10 [1.17.38.11] CARDLYGADDLW in-frame + cctctggattcacctttagtagatattggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacgtattaatgaagatgggaggaccacaacctacgcggactccgtgaatggccgattcctcatctccagagacaacgccaagaatacgttgtatctgcagatgagcagtctgagagtcgaggacacggccatgtattattgtgcaagagatctatatggtgccgatgacctctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22314 JY8QFUQ01DI0MX unproductive (see comment) Homsap IGHV3-9*01 F 796 85.65 185/216 nt 85.19 184/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 151 78.0 39/50 nt Homsap IGHD6-19*01 F 2 7 8 X 7.8.X [1.17.38.11] CGA*RSLVWA#LDLW out-of-frame - stop codons in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 13 in the user submitted sequence), (cause frameshift) cgttggattcactttaatgaacatggcatgcagtgggtccggcaagctccagggaagggcctggagtgggtcgcaggtatcagcggtaatggtgatgtcataggatatgcggactctgtgaagggccgagtcaccgtctccagagacaacgccaaagactctctatatttgcagatggacagtctgagagttaatgacacggccttatattattgtggcgcatagcgaagcctggtctgggcgccttagatctctggggccgtggaacaatggtcaccgtctctgaagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22315 JY8QFUQ01DNADY productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ3*01 F 142 76.0 38/50 nt Homsap IGHD3-16*01 F 3 8 8 12 8.8.12 [2.17.38.11] CARDDGGHMTLDVW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 85 of V-REGION: 'GG' (2 nucleotides at position 160 to 161 in the user submitted sequence), (cause frameshift); atgtctggattcacatttagaagctattccatgaattgggtccgccaggctccagggaaggggctggagtgggtctcagctgtcagtggtggtgggggcgccacaaactacgcggagtccgtgaagggccggttcaccatctccagagacaattccaggGGggcacggtgttcttacaaatgaacagcctgagagtcgaagacacagccttatattattgtgcgagagatgacggcggacacatgactttagatgtctggggccaagggacaatggtcagcgtgctctccggcctccaccaagggcccatcggtcttccccccgtggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcc 22316 JY8QFUQ01AOR6O productive (see comment) Homsap IGHV3-23*03 F, or Homsap IGHV3-23*05 F (see comment) 683 80.0 172/215 nt 79.53 171/215 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD3-16*01 F 3 8 7 17 8.7.17 [1.17.38.11] CVRDAETTVSGVAGWFDPW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in CDR2-IMGT, from codon 64 of V-REGION: 3 nucleotides (from position 99 in the user submitted sequence), (do not cause frameshift) cctctggattcagctttagcgattttgccatgagttgggtccgccaacctccaggaaaggggctggagtgggtcgcaagtgttgacagaggtggcactacatactatgcaggctccatgaagggccggctcgccgtctctagagacgatgtcgacaagacagtgagtctgcagatgaacaatctgacagtcgaggacacggccacatatcactgtgtgagagacgccgagacgacggtgtcgggagtcgctggctggttcgacccctggggccagggaaccctggtcaccgtctccgcagcttccacccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22317 JY8QFUQ01A7BVQ productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 837 87.16 190/218 nt 85.78 187/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-15*01 F 1 8 7 11 8.7.11 [2.17.38.11] CARDGEWEMLDHW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'C' (1 nucleotides at position 214 to 214 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 59 of V-REGION: 1 nucleotides (from position 92 in the user submitted sequence), (cause frameshift) gcctccggattcaccttcagtaggtattggatgtattgggtccgccaagctccaggcaaAGggggctggtntgggtctcacgcattaaaagtgtgggacgagtgcaacctacgcggactccgtgaagggccgattcaccacctccagagacaacgccaaggaaacgatgtatctgcacatgaacagcctgagagtcgacgacacggcgacataCtttttgtgcaagagacggggagtgggagatgcttgaccactggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22318 JY8QFUQ01DHT4K productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 931 92.59 200/216 nt 92.13 199/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-10*01 F 2 8 6 15 8.6.15 [2.17.38.11] CARDMGSGRYFEPYDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 58 of V-REGION: 1 nucleotides (from position 89 in the user submitted sequence), (cause frameshift) agcctctggattcaccgtcagtagcagcttcatgacttgggtccgccaggctccaggaaagggactggagtgggtctcagtgctttatgtcgtggtaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatttgcaactgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatatgggttcgggaagatattttgaaccttatgactactggggccagggaaccccggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcacccttctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacgtgtcgtggaactcagg 22319 JY8QFUQ01B95D8 No results 22320 JY8QFUQ01AUADL productive (see comment) Homsap IGHV3-30*07 F 847 87.67 192/219 nt 86.76 190/219 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-22*01 F 2 8 8 12 8.8.12 [2.17.38.11] CASLGSYESSGPRW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); gcctctggattcctcttcagtagttatgctatacactgggtccgccaggctccaggcaaGggggcttgagtgggtggcggttgtttcatatgatggaaataataaattttacgcagactctgtgaaggGgtcgattcagcctctccagagacaactccaagagcacggttgatctgcaaatggacaacttgagatccgaagacacggctgtatattattgtgcgagcctcggttcctatgagagcagtggtccccgatggggcccgggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22321 JY8QFUQ01C3IEC unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 111 65.0 39/60 nt 8 X X 8.X.X [2.10.X.X] null - No rearrangement found gcctccggattcacctttagtagtttctggatgcactgggtccagggcttcttcccccca 22322 JY8QFUQ01B7J6S productive (see comment) Homsap IGHV1-24*01 F 988 96.24 205/213 nt 95.77 204/213 nt Homsap IGHJ5*02 F 141 77.08 37/48 nt Homsap IGHD5-18*01 F 1 8 8 7 8.8.7 [X.17.38.11] CAIGAMATW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); ggaaaaaccctcactgaagtatccatgcactgggtgcgacaggctcctggaaAaagggcttgagtggatgggaggatttgatcctgaagatggtgaaataatctacgcacagaagttccagggcagaatcaccgtgaccgaggacacatctacagacacagcctacatggagctgagcagcctgagatctgaagacacggccgtgtattactgtgcaataggagctatggccacctggggccagggaaccctggtcaccgtcgactcagcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22323 JY8QFUQ01BV9XN unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 824 86.7 189/218 nt Homsap IGHJ1*01 F (see comment) 125 71.15 37/52 nt Homsap IGHD5-24*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CVGQERWPPSEPPV#W out-of-frame - Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cctctggattcagttttagtaattatgtcatgacttgggtccgccaggctccagggaaggggctggagaggatttgtcttataagtggtagtggtgctaggacatcctacgcagactccgtgaagggccggttcaccatctcccgagacaactccgagaacaaggtgtctctgcagatgaacaacctgagagccgaagacacggccatatattactgtgtggggcaagaacgatggccaccgtcggagccccccgtcctggggccagggaactgtggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22324 JY8QFUQ01CGUN6 productive Homsap IGHV1-3*01 F 863 89.3 192/215 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD6-25*01 F 1 8 8 13 8.8.13 [0.17.38.11] CARDGYRSGNGADYW in-frame - tgggatacagcttcactaactacaatatccattgggtgcgccaggcccccggacaagggcttgagtgggtgggatggatcaacgctggcaatggcaatacaagatattcacagaaattgcagggcagagtcaccatttccagggacacatccgcgagcattgccaacatggagttgagcagcctgagatatgaagacacggctgtatattattgtgcgagagacggctataggagtggcaacggggctgactattggggccagggaaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcgtcgcatgcctggtccagggctttttccccca 22325 JY8QFUQ01BGYG5 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 55 100.0 11/11 nt 1 X X 1.X.X [2.X.X.X] null + No rearrangement found gcctctggatt 22326 JY8QFUQ01CIQN4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 851 88.07 192/218 nt 86.7 189/218 nt Homsap IGHJ4*02 F 222 95.83 46/48 nt Homsap IGHD2-21*02 F 2 8 8 15 8.8.15 [1.17.38.11] CVKESSPWGGDDYFDFW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 42 of V-REGION: 'G' (1 nucleotides at position 40 to 40 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 59 to 60 in the user submitted sequence), (cause frameshift); cctctggatttaacttCgggcagctatgccatgagctggGgtccgccaggctccagggGAagggggctggagtgggtctcacttattactggtcgtggagatcgcacaaattacgcagagtctctggagggtcggttcaccatctccagagacaattccgacaacactctttatcttcaaatgaacagcctgagagccgaagacacggccatatattactgtgtgaaagagtcttctccctgggggggtgacgactactttgacttttggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 22327 JY8QFUQ01AZGQ9 unproductive Homsap IGHV4-39*03 F 996 94.98 208/219 nt 94.52 207/219 nt Homsap IGHJ4*02 F 87 64.58 31/48 nt Homsap IGHD6-13*01 F 2 10 7 X 10.7.X [1.17.38.11] CARDRYVVDSSWYGNIFRTP## out-of-frame - in CDR1-IMGT at codon 36 of V-REGION: 'C' (1 nucleotides at position 28 to 28 in the user submitted sequence), (cause frameshift); ctctggtggctccatcagcagtactagCttactactggggctggatccgccagcccccagggaaggggctggagtggattggtaacattcattctagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatgtccgtagacacgtccaagaaccagttctccctgaggctgagttctgtgaccgccgcagacacggccgtgtattattgtgcgagagatcgatatgtcgtggacagtagctggtacggcaacatttttcgaacccctgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22328 JY8QFUQ01CP28N unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*03 F or Homsap IGHV3-11*04 F or Homsap IGHV3-11*05 F or Homsap IGHV3-11*06 F or Homsap IGHV3-13*01 F or Homsap IGHV3-13*02 F or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-15*01 F or Homsap IGHV3-15*02 F or Homsap IGHV3-15*03 F or Homsap IGHV3-15*04 F 50 100.0 10/10 nt 1 X X 1.X.X [1.X.X.X] null + No rearrangement found cctctggatt 22329 JY8QFUQ01CLYL9 productive Homsap IGHV3-30*04 F, or Homsap IGHV3-30-3*03 F 873 89.4 194/217 nt Homsap IGHJ1*01 F (see comment) 179 82.69 43/52 nt Homsap IGHD2-21*02 F 2 8 8 8 8.8.8 [1.17.38.11] CSSGGDYPNW in-frame + Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) ctctggattcgacttcgatggccgtgctatgcactgggtccgccaggctccaggcaaggggctggagtgggtggcagttatctcatatgatggaaatgataaaaactacgcagactccgtgaggggccgattcaccatctccagagacaattctaaggacacgctgtttttgcaaatgaacagcctgagacatgaagacacgggtgaatatttctgttcttcaggaggtgactacccgaactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 22330 JY8QFUQ01BX6MG productive Homsap IGHV3-11*01 F 801 85.71 186/217 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-21*02 F 2 8 8 18 8.8.18 [1.17.38.11] CAGSFCGGGCLWPTYHFENW in-frame + ctctggattcccctttaaggactactccatgaactggatccgccaggctccagggaagggactggagtggatttcatacatgagcagcactggtgagaccatatattacgcggactttgtgaagggccgattcaccatctccagggacaccgccaagaatctgttgtttctgcaaatgaattacctgcgagacgaggacacggccatgtattactgtgcgggatcattttgtggtggtggctgcttgtggcccacatatcactttgaaaactggggccagggagccctggtcaccgtctcgtcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22331 JY8QFUQ01CE5GY unproductive Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1090 100.0 219/219 nt Homsap IGHJ4*03 F 105 68.75 33/48 nt Homsap IGHD2-2*01 F 3 8 8 X 8.8.X [2.17.38.11] CARGHCISTSCYWEIHYYYGMDV## out-of-frame - gcctctggattcaccttcagtagctatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtagtagttacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagggcattgtattagtaccagctgctattgggagattcactactactacggtatggacgtctgggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactca 22332 JY8QFUQ01B12BF productive (see comment) Homsap IGHV4-61*02 F 816 85.91 189/220 nt 85.0 187/220 nt Homsap IGHJ5*01 F, or Homsap IGHJ5*02 F 201 88.24 45/51 nt Homsap IGHD3-10*01 F 2 10 7 18 10.7.18 [1.17.37.11] CAREDYYGSGSYGRAWFDSW in-frame - Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 63 of V-REGION: 'C' (1 nucleotides at position 99 to 99 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 68 of V-REGION: 1 nucleotides (from position 116 in the user submitted sequence), (cause frameshift) tctctggaggctccatcagcagtggaagttactactggacctggatccggcagcccgccgggaagactctggagtggattgggcgcttctacagtcgtCgggggtgtcgactacaaccctccctcaggggtcgagtcaccatttcagcggacacgtccaagagccagttctcccttaatctgacttctgcgaccgccactgacacggccgtgtatttctgtgcgagagaggattactatggttcggggagctatgggcgggcctggttcgactcctggggccagggaatcctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22333 JY8QFUQ01BCS41 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 928 91.32 200/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 142 76.0 38/50 nt Homsap IGHD5-18*01 F 3 8 8 6 8.8.6 [2.17.38.11] CASYGQWL in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 55 of V-REGION: 'AGT' (3 nucleotides at position 79 to 81 in the user submitted sequence), (do not cause frameshift); gcctcgggactcatgtttagcagctatgccatgacctgggtccgccaggctccagggaaggggctggagtgggtctcaAGTgtcagtagtagtactggttatttcacatactacacagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgagcagcctgagagccgaagacacggccgtatattattgcgctagttacgggcagtggctgggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatccgtcttcccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22334 JY8QFUQ01AR779 productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 977 94.5 206/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-18*01 F 3 8 8 12 8.8.12 [1.17.38.11] CAKDRGYSYGFDYW in-frame + cctctggattcacctttaccacctatgccatgagttgggtccgccaggctccagggaaggggctggagtgggtctcgactatgagtggtagtggtggtagcacattctacgcggactccgtgaagggccggttcaccatctccagagacaattccaagaacacggtgtatctacaaatgaacagcctgagagccgaggacacggccgtttattattgtgcgaaagatcgaggatacagctatggctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22335 JY8QFUQ01BSPH1 No results 22336 JY8QFUQ01DH3S3 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 897 90.0 198/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found agcctctggattcacgtttggcagccacgccatgagctgggtccgccaggctccagggaaggggctggagtacgtctcaattgttactggtagcggacgcagcacatactacgcagagtctgtgaagggccggttcaccgtctccagagacaattccaaggacaccctgtatctgcaaatggacagcctgagagccgaggacacggccgtgtattattgtgcgaaagaacaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22337 JY8QFUQ01A56SJ unproductive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 867 89.72 192/214 nt 88.79 190/214 nt Homsap IGHJ3*01 F (see comment) 169 82.0 41/50 nt Homsap IGHD3-10*02 F 1 8 8 20 8.8.20 [0.17.38.11] CARVGGR***RLLCRGDAMDVW in-frame + stop codons Other possibilities: Homsap_IGHJ6*01 and Homsap_IGHJ6*04 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'C' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 71 of V-REGION: 'T' (1 nucleotides at position 118 to 118 in the user submitted sequence), (cause frameshift); tggatacaccttCccccgaccactatgtacactgggtgcgacaggcccctggacaagggcttgagtggatgggacggatcagccctaacactggcggcgcacactatggacagaggtTttcagggcagggtcaccatgaccagggacacgtccatcaccacagtctacatggaattgagcaggctgagtccggatgacacggccgtgtattattgtgcgagagttggggggagatgatgatgacggttactatgtcggggagacgctatggacgtctggggccaggggaccacggtcaccgtctcctcagcttccaccaagggcccatccgtcttccccctggngccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 22338 JY8QFUQ01AA6GL productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 910 90.87 199/219 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD5-12*01 F 1 8 8 14 8.8.14 [2.17.38.11] CAKDLFQVSTTYFDYW in-frame + gcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaatgcgctgtttctgcagatgaacagcctgagagctgacgacacggctgtgtattactgtgcgaaagacctctttcaggtgtctacgacttactttgactactggggccggggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 22339 JY8QFUQ01AOMJ0 unproductive Homsap IGHV3-7*02 F 922 92.13 199/216 nt 91.67 198/216 nt Homsap IGHJ5*02 F 102 66.67 34/51 nt Homsap IGHD5-12*01 F 2 7 8 X 7.8.X [1.17.38.11] CARDQVTEDY## out-of-frame - in CDR1-IMGT, from codon 29 of V-REGION: 1 nucleotides (from position 11 in the user submitted sequence), (cause frameshift) ctctggattccttttagaacctattggatgagttgggtccgccaggctccagggaaagggctggagtgggtggcccacataaaccaagatggacgtgaggcatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaattcagtatatctgcaaatgaacagtctgagagccgaggacaccgctatgtattattgtgccagagatcaagtgactgaagactactgggggccagggaaccctggtcagtgtctcctcagcctccaccaagggccccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg 22340 JY8QFUQ01CDKRX No results 22341 JY8QFUQ01B28Z6 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 905 90.83 198/218 nt 90.37 197/218 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD5-24*01 ORF 1 8 8 12 8.8.12 [1.17.38.11] CARDRLTISALDYW in-frame + Potentially, because of detected insertion/deletion in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 126 to 126 in the user submitted sequence), (cause frameshift); cctctggattcacctttaacaactacgccatgtcctgggtccgccaggctccagggaaggggcttgagtgggtctcagctataactgatagcggtctttacacatactacgcagactccgtgaggGggccggttcaccgtctccagagacacttccaagaacacgctgtttctgcaaatggacagcctgagagccgaggacacggccgtatatttctgtgcgagggatagactcacgatttcagcccttgattactggggccagggagccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22342 JY8QFUQ01CBDVF productive (see comment) Homsap IGHV3-66*01 F, or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 949 93.52 202/216 nt 93.06 201/216 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD4-23*01 ORF 2 8 7 10 8.7.10 [2.17.38.11] CARGDGVKDDYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 37 of V-REGION: 'A' (1 nucleotides at position 26 to 26 in the user submitted sequence), (cause frameshift); gtctctggattcaccgtcaatagaaAactacatgagctgggtccgccaggctccagggaagggactggagtgggtctcagttatttccagcggtggttccacatactacgcaaactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtatatcttcaaatgaacagcctgagagtcgacgacacggctgtgtattactgtgcgagaggggacggggttaaggatgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22343 JY8QFUQ01DL5J0 No results 22344 JY8QFUQ01CD2W2 productive (see comment) Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 2 8 8 11 8.8.11 [2.17.38.11] CAISSGFYSTGYW in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtacctattggatgggctgggtccgccaggctccagGggaaggggctggagtgggtggccaacataaaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggtttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 22345 JY8QFUQ01C7A9V unproductive Homsap IGHV3-7*01 F 920 90.95 201/221 nt Homsap IGHJ5*02 F (see comment) 165 80.39 41/51 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [2.17.38.11] CARDSPHQP#DPW out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) cagcctctggattcacctttagttatcactggatgagttgggtccgccaggctccagggaaggggctggagtgggtggccctcataaggcaagatggaagtgaggaatactatgtggactctgtgaggggccgattcagcttctccagagacaacgccaagaattcagtgtacttggaaatgaacaacctgagagccgaggacacggctgtttattactgtgcgagagattccccccatcagcctacgatccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcaccgtccgagagcacagcggccctgggctgcctggtccaaggactcacttccccgaaccggtgacggtcgtcgtgaactcagg 22346 JY8QFUQ01C385E productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 865 88.18 194/220 nt 85.91 189/220 nt Homsap IGHJ1*01 F 98 65.38 34/52 nt Homsap IGHD4-23*01 ORF 2 8 8 17 8.8.17 [2.17.38.11] CAKNNPPYDRSGPLYRLLG in-frame - Potentially, because of detected insertion/deletion in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 37 to 37 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 58 to 58 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 81 to 81 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 57 of V-REGION: 'G' (1 nucleotides at position 91 to 91 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'G' (1 nucleotides at position 130 to 130 in the user submitted sequence), (cause frameshift); agcctcctgggttcattttggccacnataccatgagGcttggtccgccaggctccagGggaaggggctggagtgggtctcGaactattggGtaatagtggtgatattacatactacgcagactccgcgaGggggccggttcaccatctccagagacaattcccagaacacactgtatctgcaagtgaacagcctgagagccgaggacacggccgtatattactgtgcgaaaaataaccccccctatgacaggagtggtccattataccgactactgggggccaggggaatcctggtcaccgtctcttcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccag 22347 JY8QFUQ01CCG46 productive (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 945 93.09 202/217 nt 92.63 201/217 nt Homsap IGHJ4*02 F 159 81.25 39/48 nt Homsap IGHD1-26*01 F 3 8 8 10 8.8.10 [1.17.38.11] CTRDIGGRYSYW in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift); ctccggattcacctTttagtagttactggatgcactgggtccgccaagctccaggggagggactggtgtgggtctcacggactaatgaagatgggagtatcacaaactacgcggactccgtggaggaccgattcaccatctccagagacaacgccaagaacaggctgtatctgcaaatgaacagtctgagagccgaggacacggctgtgtattactgtacaagagacatcggtgggcgctactcctactggggccagggaatcctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacacgcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22348 JY8QFUQ01B3796 No results 22349 JY8QFUQ01CP3KB unproductive Homsap IGHV3-7*01 F 1027 96.8 212/219 nt 96.35 211/219 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.38.11] CAISSGFLLDG#YW out-of-frame + in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 86 to 86 in the user submitted sequence), (cause frameshift); gcctctggattcacctttagtacctattggatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAaacaagatggaagtgacaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacggcaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtctattactgtgcgattagtagtggttttttactcgacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtcccagggcttcttccccca 22350 JY8QFUQ01C66E4 unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 121 54.48 73/134 nt 8 8 X 8.8.X [2.17.9.X] null + No rearrangement found stop codons gcctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccc 22351 JY8QFUQ01AZ7EU productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 954 93.55 203/217 nt Homsap IGHJ6*02 F (see comment) 94 61.29 38/62 nt Homsap IGHD2-15*01 F 2 8 8 21 8.8.21 [1.17.38.11] CAKTGGQCSGGNCYLHYYGMDVW in-frame + Other possibilities: Homsap_IGHJ4*03 (shorter alignment but highest percentage of identity) ctctaaattcacctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtcacaggtattagtggtggtggtgaaaacacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagagcatgttgtatctgcaaatgaacagcctgagagccgaagacacggccgtattttactgtgcgaaaactggcggtcaatgcagtggtggtaactgctatttgcactactacggtatggacgtctggggccaaagggaccacggtcaccgtctcctcatcatccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaaacgtggtcatcgcctgcctggtccagggcttcttccc 22352 JY8QFUQ01A7FKM productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 950 93.12 203/218 nt 91.74 200/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [1.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'A' (1 nucleotides at position 57 to 57 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'G' (1 nucleotides at position 75 to 75 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 117 to 117 in the user submitted sequence), (cause frameshift); gttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgggAaaaggcctggagtggatGggggatcatctatcctggtacctctgagaccagatacagccCcgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgcctacgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22353 JY8QFUQ01BYYQ5 productive (see comment) Homsap IGHV3-7*01 F 995 95.41 208/218 nt 94.95 207/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAKGGGNGDLDYW in-frame - Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 28 of V-REGION: 'G' (1 nucleotides at position 9 to 9 in the user submitted sequence), (cause frameshift); cctctggaGttcacctttagtaaccattggatgaactgggtccgccaggctccagggaaggggctggagtgggtggccaacataatgccagatggaggtgagaaattctatgtggactctgtgaagggccggttcaccatctccagagacagcgccaagaactcactgtatttgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaaggggggtggtaacggcgaccttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22354 JY8QFUQ01BYVH4 unknown (see comment) Homsap IGHV3-7*02 F 109 59.04 49/83 nt 8 1 X 8.1.X [1.17.X.X] null - No rearrangement found ctctggattcacctttagcagctatgccatgagctgggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22355 JY8QFUQ01CC47V unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 882 89.86 195/217 nt 89.4 194/217 nt Homsap IGHJ4*02 F 132 75.0 36/48 nt Homsap IGHD6-19*01 F 3 8 8 X 8.8.X [1.17.38.11] CANEVGYCSGRG# out-of-frame - in FR3-IMGT at codon 88 of V-REGION: 'A' (1 nucleotides at position 167 to 167 in the user submitted sequence), (cause frameshift); ctctggattcacctttaacctctatgtcatgcactggttccgccaggctccagggaaggggctagagtgggtctcaactattcgtgccaggggtgataggacacactacgcagactccgtgaagggccgcttcaccatctccagagacaattccaagaacacgctgAtttttgcaaatgtacagcctgagagtcgaggacacggccatatattactgtgcgaacgaagtcggatattgtagtggtcgggggggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccag 22356 JY8QFUQ01B2LDP productive (see comment) Homsap IGHV3-7*01 F 885 90.65 194/214 nt 89.72 192/214 nt Homsap IGHJ5*02 F (see comment) 192 86.27 44/51 nt Homsap IGHD4-23*01 ORF 3 8 8 12 8.8.12 [0.17.38.11] CARGTSVDPGIDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 13 to 13 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 55 to 55 in the user submitted sequence), (cause frameshift); tggattcaccttTtagtaattattggatgcactgggtccgccaggtttcagggaGgggggctggagtgcgtggccaccataaacgaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 22357 JY8QFUQ01DABIC productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 973 94.06 206/219 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [2.17.38.11] CAKVVWSLWYFDLW in-frame + gcctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22358 JY8QFUQ01CR05A productive Homsap IGHV3-30*01 F 950 93.12 203/218 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD2-15*01 F 2 8 8 13 8.8.13 [1.17.38.11] CPKTGPGHSSPFDYW in-frame + cctctggattcaccttccgaagttatgatctgcactgggtccgccaggctccaggcaaggggctagagtgggtggcatttatatcaaacgatggaagtgacacagactacgcagactccgtgaagggccgattcaccatctccagagacaattccaagaagacgctatatctgcaaatgaacagcctgagagttgaggacacggctgtgtattactgtccgaaaaccggccccggtcatagcagcccctttgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22359 JY8QFUQ01C8W1E No results 22360 JY8QFUQ01AQ6MS productive Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 996 95.0 209/220 nt Homsap IGHJ3*02 F 223 94.0 47/50 nt Homsap IGHD2-21*02 F 2 8 8 17 8.8.17 [2.17.38.11] CARPYCGGDCHNRGAFDIW in-frame - ggcctctggattcagcttcaatagttactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcacatattaatattgatgggagtaccacagactacgcggactccgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgaggccatattgtggtggtgactgccacaatcgaggggcttttgatatctggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22361 JY8QFUQ01AF1QO unproductive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1051 97.3 216/222 nt 96.85 215/222 nt Homsap IGHJ4*02 F 213 93.75 45/48 nt Homsap IGHD4-11*01 ORF 2 10 7 11 10.7.11 [2.17.38.11] CARLDYTR*FDYW in-frame + stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggGggctggagtggattgggagtatccaatatagtgggagcacctattacaatccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgacctctgtggccgccgcagacacggctgtgtattactgtgcgagactcgactacactaggtagtttgactactggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22362 JY8QFUQ01BZOJU productive Homsap IGHV3-9*01 F 892 89.95 197/219 nt Homsap IGHJ5*02 F 210 90.2 46/51 nt Homsap IGHD1-26*01 F 1 8 8 13 8.8.13 [2.17.38.11] CVKGAGTTVNWFDIW in-frame + cctctgggattcacctttgatggttatgccatgcactgggtccggcaagctccaggggagggcctggaatgggtctcaagtattaactggaatagtgatacaatagactacgcggactctgtgaagggccgattcactatctccagagacaacgccaagcactccctgtatctacaaatgaacaatctgagaaatgaggacacggccttgtattactgtgtaaaaggagcgggaactaccgtcaactggttcgacatctggggccagggaaccctggtcaccgtctctttagcatccccgaccagccccaaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22363 JY8QFUQ01ASIT3 productive (see comment) Homsap IGHV3-7*01 F 891 90.32 196/217 nt 89.86 195/217 nt Homsap IGHJ3*01 F 223 94.0 47/50 nt Homsap IGHD1-14*01 ORF 1 8 8 14 8.8.14 [1.17.38.11] CARVIPGRGNYAFDVW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 89 of V-REGION: 'T' (1 nucleotides at position 170 to 170 in the user submitted sequence), (cause frameshift); ctctggattcgactttggtagttattggatgagttgggtccgccaggctccagggaagggactggagtgggtggccagcataaagcgagatgcaagtgagaagtaccatgtggaatctgtgcagagacgattcaccatcttcagagacaacgtcaggaactcactgtatTttgcagatgaacagcctgagagacgaggacacggctgtgtattactgtgcgagagttattcccggccggggaaactatgcttttgatgtctggggccgagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22364 JY8QFUQ01B3LY5 unknown (see comment) Homsap IGHV1-45*01 F, or Homsap IGHV1-45*02 F or Homsap IGHV1-46*01 F or Homsap IGHV1-46*02 F or Homsap IGHV1-46*03 F or Homsap IGHV1-69*01 F or Homsap IGHV1-69*03 F or Homsap IGHV1-69*06 F or Homsap IGHV1-69*09 F or Homsap IGHV1-69D*01 F 102 58.97 46/78 nt 57.69 45/78 nt 1 X X 1.X.X [24.X.X.X] null + No rearrangement found in FR1-IMGT, from codon 7 of V-REGION: 2 nucleotides (from position 96 in the user submitted sequence), (cause frameshift) cctgagttccacgacaccgtcaccggttcgggggaagtagtccttgaccaggcagcccagggccgctgtgccccccagaggtgctcttggaggagggtgccaggggggaagaccgatgggcccttggtggaggctactgacgaagccaccagaga 22365 JY8QFUQ01CE0WI productive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 962 94.42 203/215 nt Homsap IGHJ5*02 F 246 98.04 50/51 nt Homsap IGHD4-17*01 F 3 8 7 16 8.7.16 [1.17.38.11] CARGSVTTWRRENWFDPW in-frame - tctctggtggctccatcagtacttattactggaactggatccggcagcccccagggaagggactggagtggattgggtatatccataacagtgggagtagcaactacaacccctccctcaagagtcgagtcaacatatctgtagacgcgtccaagaaccagttctccctgaagctgacctctgtgaccgctgcggacacggccgtttattactgtgcgagaggttcggtgactacgtggagacgggagaactggttcgacccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22366 JY8QFUQ01BFMOW unproductive Homsap IGHV3-11*01 F 883 89.5 196/219 nt 88.58 194/219 nt Homsap IGHJ3*02 F (see comment) 106 68.0 34/50 nt Homsap IGHD2-15*01 F 3 8 8 X 8.8.X [2.17.38.11] CARDDSCSGGSCYEY## out-of-frame - Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 129 to 129 in the user submitted sequence), (cause frameshift); acctctggattcagtttcagtgactactacatgagttggatccgccaggctccagggagGggggctggagtgggtttcatatattgatagcggtggtaccgccatgtactactcagactccgtgaaggGgccgattcaccatctccagggacaacgccaagaagtcactgtttctgcaaatgagtagcctgagagccgaagacacggccgtgtactattgtgcgagagatgactcttgtagtggtggtagctgttacgaatactgggggccagggaaccccggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccaggggctt 22367 JY8QFUQ01CAGQP productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 1009 95.89 210/219 nt 94.98 208/219 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD5-24*01 ORF 3 8 8 14 8.8.14 [2.17.38.11] CAKDGARGGGSCFNSW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 18 to 18 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 63 to 63 in the user submitted sequence), (cause frameshift); gcctctggattcaccttTtagaagctatgccatgagctgggtccgccaggttccagggaaggGggctggagtgggtctcagctattagtggtaatggtgctaacacatactacgcagactccgtgaagggccgattcaccatctccagagacaatttcaagaacacgctgtctctgcaaatgaacagcctgagagccgaggacacggccctatattactgtgcgaaagatggcgctagaggtggcggcagttgctttaactcctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 22368 JY8QFUQ01B8CLS unproductive Homsap IGHV3-30*01 F, or Homsap IGHV3-30*07 F 941 92.66 202/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 150 79.17 38/48 nt Homsap IGHD3-22*01 F 3 8 8 X 8.8.X [2.17.37.11] CVRDDDTSGHYSLFKY## out-of-frame - in FR3-IMGT, from codon 96 of V-REGION: 1 nucleotides (from position 195 in the user submitted sequence), (cause frameshift) ggctctggattcaccttcagcaagtatgccatgagctgggtccgccaggctccaggcaaggggctagagtgggtggcagtcatattatatgatggaagtaacagttattacgcagactccgtgaagggccgattcaccgtctccagagacaattccaagaacacactgtatctgcaaatgaacagcctgagagcgaggacacggctgtatattactgtgtgagagatgatgataccagtggtcactactctctgtttaaatattgggggccagggaaccctggtcaccgtctcctcagcatcccccgaccagcccccaaggtcttccccgctgagcctctgcagcaccccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22369 JY8QFUQ01A3PQF unproductive (see comment) Homsap IGHV4-61*02 F 903 89.69 200/223 nt 88.79 198/223 nt Homsap IGHJ5*02 F 129 72.55 37/51 nt Homsap IGHD6-19*01 F 2 10 7 X 10.7.X [2.17.38.11] CARQGG**WTLE*LL# out-of-frame + stop codons in CDR2-IMGT at codon 58 of V-REGION: 'G' (1 nucleotides at position 95 to 95 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 121 to 121 in the user submitted sequence), (cause frameshift); tgtctccggtggctccatcagtactggttattactactggagctggatccggcagtccgccgggaagggactggaatggattgggcgcatgtctGcccagaggggacagcaactacaaccCcctccctccagagtcgagtcaccatatccatagacacgtccaagaaccagttctccctgaggctgacctctgtgagcgccgcagacacggccgtgtatttttgtgcgagacaagggggatagtagtggaccctggaatgactactgggggccagggaatcctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggcagcacctccgagagcaccagcggccctgggctgccctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22370 JY8QFUQ01B6UM2 productive (see comment) Homsap IGHV3-33*04 F (see comment) 706 81.02 175/216 nt 80.09 173/216 nt Homsap IGHJ4*02 F 163 82.98 39/47 nt Homsap IGHD2-21*01 F 3 8 8 7 8.8.7 [1.16.38.11] CARDILDYW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (81,02% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT, from codon 44 of V-REGION: 1 nucleotides (from position 45 in the user submitted sequence), (cause frameshift)in FR2-IMGT, from codon 52 of V-REGION: 1 nucleotides (from position 69 in the user submitted sequence), (cause frameshift) catttggattccctttcagcgactatggcatgcactgggtccgcagactccagacaagggactagaattgtggccattatctggcatgacggaagtcagcaattctatgcagactccgtgctgggtcgattcaccgtctccagagacaattccgacaacactctccagttgcagctgagcaggttgacagccgaagacacggctatttattattgtgcgagagatattttggactactggggccagggaacccaggtcatcgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22371 JY8QFUQ01CR7D8 unknown (see comment) Homsap IGHV3-21*01 F, or Homsap IGHV3-21*02 F 1040 97.71 213/218 nt 8 8 X 8.8.X [1.17.38.X] null + No rearrangement found cctctggattcaccttcagtaactatagcatgaactgggtccgccaggctccagggaaggggctggagtgggtctcatccattagtagtagtgctaggtacatatactacgcagactcagtgaagggccgattcaccatctccagagacaacgccaagaactcactgtctctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgcgagacctgaccgggtatagcagcgaaccgaaactactggggccagggaagccctggctgnaccgtctcctcagcatcccccgaccagccccaaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 22372 JY8QFUQ01CKDV6 unproductive Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 859 88.89 192/216 nt Homsap IGHJ3*01 F, or Homsap IGHJ3*02 F 124 72.0 36/50 nt Homsap IGHD2-15*01 F 3 8 7 X 8.7.X [2.17.38.11] CARDPRDYCSGGYCFVGAFDI## out-of-frame - gtctctggtggctccatgaggaattattactggagctggatccggcagtccccagggaagggactggagttgataggaactgtctattacactgggcgcacggagtacaacccctccctcaagagtcgactcaccttatcactagacacgtccaagaaccagttctccctaaagctgggctctgtgaccgctgcggactcggccatttattactgtgcgagagacccccgagactattgtagtggtggttactgttttgttggtgcttttgatatctgggggccaagggacaaaggtcaccgtctcttcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22373 JY8QFUQ01B2WGC productive (see comment) Homsap IGHV4-59*08 F 881 90.23 194/215 nt 88.84 191/215 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD6-6*01 F 1 8 7 15 8.7.15 [1.17.38.11] CARNPSYSNSHQHCDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 46 of V-REGION: 'CA' (2 nucleotides at position 53 to 54 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 97 to 97 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 115 to 115 in the user submitted sequence), (cause frameshift); tctctggtgtctccatcagtagttcctactggagttggatccggcagcccccCAgggaaggggcctggagtggattggttatgtctattatactggGgggcaccgactccaaccCcctccctcaagagtcgagtcgccatatcaatggacacgtccaagaaccagttctccctgaagctgaactctgtgaccgccgcagacacggccgtctatttttgtgcgagaaatccctcttatagcaattcgcaccagcattgtgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccag 22374 JY8QFUQ01CGJDB productive (see comment) Homsap IGHV4-4*07 F (see comment) 715 81.48 176/216 nt 80.56 174/216 nt Homsap IGHJ4*02 F (see comment) 195 89.58 43/48 nt Homsap IGHD3-9*01 F 1 8 7 16 8.7.16 [2.17.38.11] CARECLDSLGRPSHLDSW in-frame + Potentially, because of detected insertion/deletion Low V-REGION identity (81,48% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 37 of V-REGION: 'CTGACT' (6 nucleotides at position 26 to 31 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 69 of V-REGION: 'C' (1 nucleotides at position 119 to 119 in the user submitted sequence), (cause frameshift); gtctctggtggcccgatcaagaataCTGACTactattggacatggatccggcagcccgccgggaggggactggagtgggtcgggcgtgtctatttgaatggcaatgccgactacaaccCcctccttcagcagccgtctcaccatgtccattgacacgtccaggaaccaattctccctgagcttgacctctgtgaccgccgctgacacggccctctattactgtgcgagagaatgtcttgattcacttggcagaccgagtcaccttgactcctggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22375 JY8QFUQ01B4LPL unknown (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*02 F or Homsap IGHV3-23*03 F or Homsap IGHV3-23*04 F or Homsap IGHV3-23*05 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 154 89.47 34/38 nt 8 X X 8.X.X [1.3.X.X] null + No rearrangement found tctctggattcacctttgacagctacgccatgagctgg 22376 JY8QFUQ01CBLC4 unproductive (see comment) Homsap IGHV3-7*01 F 945 93.09 202/217 nt 92.17 200/217 nt Homsap IGHJ1*01 F (see comment) 80 61.54 32/52 nt Homsap IGHD3-22*01 F 1 8 8 X 8.8.X [1.17.37.11] CAISSDFYSTGH# out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 and Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 84 to 84 in the user submitted sequence), (cause frameshift); in FR3-IMGT, from codon 87 of V-REGION: 1 nucleotides (from position 165 in the user submitted sequence), (cause frameshift) gctctggattcaacttcagaacctattagatgggctgggtccgccaggctccagggaaggggctggagtgggtggccaacataAaagcacgatggaagtgacaagtactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactcatgtttttgcaaatggacagcctgagagccgaggacacggctgtgtactactgtgcgattagcagtgatttctactcgacgggccactgggccagggaaccctggtcaccgtctctcagcatcccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccc 22377 JY8QFUQ01BZIXK productive (see comment) Homsap IGHV1-2*02 F, or Homsap IGHV1-2*05 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD3-22*01 F 2 8 8 18 8.8.18 [0.17.38.11] CAREKRGQHDGSRFATNDFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'C' (1 nucleotides at position 45 to 45 in the user submitted sequence), (cause frameshift); tggatacacattcaccggctactatgtgcactgggtgcggcaggCcccctggacaaggtcttgagtggatgggacggatgaaccctaacagtggtgccacagactctgcacagaagtttcagggcagggtcaccatgaccagggacacgtccgtcaacacatattacatggagttgagcggactgaaatctgacgacacggccatctactactgtgcgagagagaagcggggacagcatgatggaagtcgttttgccacaaatgacttttggggctcgggaaccctggtcaccgtctccccgaccatccccgaccagccccaaggtcttcccgctgagcctctgagcaccccagccagatgggaacgtggtcatccgcctgctggtccaggggcttcttcccccca 22378 JY8QFUQ01CDBGI productive (see comment) Homsap IGHV3-15*01 F, or Homsap IGHV3-15*02 F 971 92.86 208/224 nt 90.62 203/224 nt Homsap IGHJ4*02 F 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 3 8 10 11 8.10.11 [1.17.38.11] CTPLARRDVLRMG in-frame + Potentially, because of detected insertion/deletion in CDR1-IMGT at codon 29 of V-REGION: 'C' (1 nucleotides at position 14 to 14 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'G' (1 nucleotides at position 60 to 60 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 54 of V-REGION: 'G' (1 nucleotides at position 78 to 78 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 85 of V-REGION: 'AT' (2 nucleotides at position 170 to 171 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 96 of V-REGION: 'T' (1 nucleotides at position 204 to 204 in the user submitted sequence), (cause frameshift); cctctggattcacCttttagtaaccattggatgaactgggtccgccaggctccagggaaGggggctggagtgggttgGgccgtattaagagcaaagctgatggtgggacaacagactacgccacacccgtgagaggcagattcaccatctcaagagatgattcaaaaaaATcacgttttatctgcaaatgaatagcctaaaaaTccgaagacacagccgtctattactgtaccccacttgcgagaagagatgtcttacgaatgggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgccatggtccagggcttcttccccca 22379 JY8QFUQ01CRKNP unproductive Homsap IGHV3-48*03 F 878 89.45 195/218 nt Homsap IGHJ5*02 F 147 76.47 39/51 nt Homsap IGHD3-3*01 F 3 8 8 X 8.8.X [1.17.38.11] CARESWWSGFYGWYD#PW out-of-frame + cctctggattcacctttagtagttctgccatgaactgggtccgccaggctccagggaagggactggagtggatttcatacattagtgatagtggtagtcgcatttactatgcagactctgtgaggggccgattcaccatctccagagacgacgccaagaacgtgctgtatctgcaaatgaacggactgcgagacgaagacacggctctttattactgtgcgagagaatcctggtggagtggcttttatgggtggtacgaccccctggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 22380 JY8QFUQ01A7Z64 unproductive (see comment) Homsap IGHV3-30*15 F 950 93.12 203/218 nt 91.28 199/218 nt Homsap IGHJ4*02 F (see comment) 96 66.67 32/48 nt Homsap IGHD5-24*01 ORF 1 8 8 X 8.8.X [1.17.38.11] CARDELPWGYNR#YYFDYW out-of-frame + stop codons Other possibilities: Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 17 to 17 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 62 to 62 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 179 to 179 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 102 of V-REGION: 'T' (1 nucleotides at position 215 to 215 in the user submitted sequence), (cause frameshift); cctctggattcaccttTtagtagatattccatgcactgggtccgccaggctccaggcaaggGggctagagtgggtggcacttatatcatacgatggaagtagaagaatctacgcagactccgtgaagggccgattcaccatctccagagacacttccaagaacacggtgtatctgcaaAatgagtagcctgagacctgaggacacggctgtgtaTttactgtgcgagagatgagctgccttggggatacaatagaatactactttgactattggggccagggaacccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatggggaacgtggtcatcgcctgcctggtccagggcttcttccc 22381 JY8QFUQ01BJ0EY unproductive Homsap IGHV4-61*02 F 925 90.99 202/222 nt 89.19 198/222 nt Homsap IGHJ2*01 F (see comment) 103 66.04 35/53 nt Homsap IGHD2-2*01 F 3 10 7 X 10.7.X [2.17.38.11] CARVVRCTTTGCSRGRMVRPP## out-of-frame - Other possibilities: Homsap_IGHJ1*01 and Homsap_IGHJ4*02 and Homsap_IGHJ5*02 and Homsap_IGHJ4*01 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in CDR1-IMGT at codon 31 of V-REGION: 'G' (1 nucleotides at position 20 to 20 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 40 of V-REGION: 'G' (1 nucleotides at position 41 to 41 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 44 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 63 of V-REGION: 'G' (1 nucleotides at position 104 to 104 in the user submitted sequence), (cause frameshift); tctctgggtggctccatcaGgcagtgatgattactactggGagctggatccggcaGgcccgccgggaagggactggagtggattgggcgtatctcttccagtgGggaacaccaactacaacccctccctcaggagtcgagtcaacatttcactagacacgtccaagacccagttctccctggagctgacctctgtgagcgccgcagacacggccgtgtattactgtgcgagggtcgttcgttgtactacgaccggctgctcaaggggtaggatggttcgaccccctgggggccaggggaaccctggtaaccgtctcctcagcatcccccgaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatggggaacgtggtcgtcgcatgcctggtccagggcttcttccccccagg 22382 JY8QFUQ01BEDF2 unproductive (see comment) Homsap IGHV3-7*01 F 982 94.52 207/219 nt Homsap IGHJ5*02 F (see comment) 183 84.31 43/51 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CARGTSVDPGD#DHW out-of-frame + stop codons Other possibilities: Homsap_IGHJ4*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) gcctctggattcacctttggtagctattggatggcctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaagcaagatggaagtgagagacactatgtggactctgtgaagggccgattcaccgtctccagagacaacgccaagaactctctgtttttgcagatgaacagcctgagagccgaggacacggctgtctactactgtgcgagagggacctcagtggacccgggggattgaccactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgctgcctggtccagggcttcttcccccca 22383 JY8QFUQ01DLVYV No results 22384 JY8QFUQ01AQFZJ unknown (see comment) Homsap IGHV3-13*01 F, or Homsap IGHV3-13*04 F or Homsap IGHV3-13*05 F or Homsap IGHV3-66*01 F or Homsap IGHV3-66*02 F or Homsap IGHV3-66*04 F 107 56.7 55/97 nt 55.67 54/97 nt 8 X X 8.X.X [17.6.X.X] null - No rearrangement found in FR1-IMGT, from codon 18 of V-REGION: 22 nucleotides (from position 111 in the user submitted sequence), (cause frameshift) ggggggaagaagccctggaccaggcaggcgatgaccacgttcccatctggctgggtgctgcagaggctcagcgggaagaccttgggggctggtcgggggatgctggggggccgccggatccaactccagtagtaaccagtcatggagccaccagagaca 22385 JY8QFUQ01AFGXD productive (see comment) Homsap IGHV5-51*01 F, or Homsap IGHV5-51*03 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD3-16*01 F 2 8 8 16 8.8.16 [2.17.38.11] CARRLNNYDSGEYAMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 47 of V-REGION: 'G' (1 nucleotides at position 56 to 56 in the user submitted sequence), (cause frameshift); ggttctggatacacgtttatgaattactggatcggctgggtgcgccagatgcccgGggaaaggcctggagtggatggggatcatctatcctggtacctctgagaccagatacagcccgtcctttcaaggccaggtcaccatttcagccgacaagtccaccagcaccgccttcgtgcagtggagcagcctgaaggccccggacaccgccatatattactgtgcgaggcgactcaataattacgactcgggagagtacgctatggacgtctggggccaagggaccacggtcaccgtctcctcaacctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22386 JY8QFUQ01AG6QZ No results 22387 JY8QFUQ01AXVCI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ2*01 F 247 96.23 51/53 nt Homsap IGHD2-21*01 F 1 8 8 12 8.8.12 [1.17.38.11] CAKVVWSLWYFDLW in-frame + cctctacattcgcctttagcaactatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagtacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22388 JY8QFUQ01BRKSA productive (see comment) Homsap IGHV3-30*01 F 869 88.99 194/218 nt 88.53 193/218 nt Homsap IGHJ6*02 F (see comment) 184 77.42 48/62 nt Homsap IGHD3-10*01 F 3 8 8 18 8.8.18 [1.17.38.11] CARGTMLRGVTKARYGLDVW in-frame + Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtacctatgctatgtactgggtccgccaggctccaggcaaggGggccagagtgggtgtcagtgatatcacatgatggaaataaggaagaatacgcagactccgtgaagggccgattcaccatttccagagacaactccaagaaaatgttgtacctgcaaatgaacaaccagcgacctgatgacacggctgtttattattgtgcgagagggactatgcttcggggagtcaccaaagcgagatacggtctggacgtctggggccaagggaccacggtcatcgtctcctcagcctccaccaaggggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22389 JY8QFUQ01BCNU6 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 927 92.17 200/217 nt 91.24 198/217 nt Homsap IGHJ2*01 F 121 69.81 37/53 nt Homsap IGHD6-13*01 F 2 8 8 X 8.8.X [1.17.38.11] CAKVVWSLWYFDL## out-of-frame - in CDR1-IMGT at codon 37 of V-REGION: 'G' (1 nucleotides at position 24 to 24 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 46 of V-REGION: 'G' (1 nucleotides at position 53 to 53 in the user submitted sequence), (cause frameshift); tctaacattcgcctttagcaactGatgccatgagctgggtccgccaggctccGagggaaggggctggagtgggtgtcagatattagtgggagtggtgttagcacacactacgcggactccgtgcagggccggttcaccatctccagagacaattcgaagaacacgctgtatctgcaaatgaacagcctgagtgccgaggacacggccgtatattactgtgcgaaagtagtctggagcctctggtacttcgatctctgggggccgtggcaccctggtcactgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcag 22390 JY8QFUQ01AEQJJ No results 22391 JY8QFUQ01BLLNO unproductive Homsap IGHV3-48*01 F 946 92.69 203/219 nt 90.87 199/219 nt Homsap IGHJ1*01 F (see comment) 98 65.38 34/52 nt Homsap IGHD5-18*01 F 2 8 8 X 8.8.X [2.17.38.11] CARERGNSYGEIDYW# out-of-frame + Other possibilities: Homsap_IGHJ4*02 and Homsap_IGHJ5*02 (highest number of consecutive identical nucleotides) or Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 53 of V-REGION: 'T' (1 nucleotides at position 76 to 76 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 65 of V-REGION: 'A' (1 nucleotides at position 106 to 106 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 91 of V-REGION: 'A' (1 nucleotides at position 181 to 181 in the user submitted sequence), (cause frameshift); cctctggttttcaccttcaggagctctggcatgaactgggtccgccaggctccagggaagGgggctggagtgggtTttcatacattagcagtagtactactaccaAaatactgcgcagactctgtgaagggccgattcaccatctccagagacaatgccaagagctcactgtatctgcaaAatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagaacgtggaaacagctatggagagattgactactggggcccaagggaaccctggtcaccgtctcctcagcttccacaagggcccatccgtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22392 JY8QFUQ01DH48J No results 22393 JY8QFUQ01BM3SO productive (see comment) Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 918 91.71 199/217 nt 91.24 198/217 nt Homsap IGHJ4*02 F (see comment) 150 79.17 38/48 nt Homsap IGHD3-10*01 F 2 8 8 15 8.8.15 [1.17.38.11] CAKDMGSGRYLEALDHW in-frame - Potentially, because of detected insertion/deletion Other possibilities: Homsap_IGHJ3*01 and Homsap_IGHJ3*02 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 29 to 29 in the user submitted sequence), (cause frameshift); gtctgacctcatatttactaaatatggcGttccactgggtccgccaggctccaggcaaggggctggagtgggtggcacttatttggtttgatggaagtaataaatattatgcagactccgtgaagggccgattcaccatctccagagacaattccaagaacacggtgtatctgcaaatggacagcctgagagccgaggacacggctgtgtatttctgtgcgaaggatatgggttcgggaagatacttagaagctcttgaccactggggcccgggaatccaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccccca 22394 JY8QFUQ01CMXMD unproductive (see comment) Homsap IGHV3-72*01 F 899 89.29 200/224 nt Homsap IGHJ5*02 F 84 62.75 32/51 nt Homsap IGHD2-15*01 F 3 8 10 10 8.10.10 [1.17.38.11] CAVAAPPL*RLG in-frame + stop codons cctctggattcaccttaagtgacttctacatggactggctccgccaggctccagggaaggggctggagtgggttggtcgcagtagaaacaaagctaatggttacagtacacaattcgccgcatctgtgatgggcagattcaccatctcaagagatgactcaaagaatttactatatctacaaatgagcagcctgaaaaccgaggacacggccatttattactgtgctgtcgcagccccccccttatgacggctgggggccagggaacccctggtcatcgtctcctcagcatccccggaccagcccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttctt 22395 JY8QFUQ01B2WG4 productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F (see comment) 774 84.33 183/217 nt 82.95 180/217 nt Homsap IGHJ1*01 F 170 80.77 42/52 nt Homsap IGHD6-19*01 F 1 8 8 16 8.8.16 [1.17.38.11] CARPDGGNGWAAKYFQMW in-frame - Potentially, because of detected insertion/deletion Low V-REGION identity (84,33% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release in FR2-IMGT at codon 49 of V-REGION: 'GG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 62 of V-REGION: 'G' (1 nucleotides at position 96 to 96 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 125 to 125 in the user submitted sequence), (cause frameshift); ctctgggttctcgtttaatagttatggcatgacatggttccgccaggctccgggggaggGGggctggagtgggtctcatctataactggaactggGgggtaacgttttctacgcagacttcgtgCaggggccggttcaccatctccagagacaattccgacaatatgttgtttctgcaaatgaacagcctgagagttgaggacacggccgtgtattactgtgcgagacctgacggaggcaatggctgggccgcaaagtactttcagatgtggggccagggcacccttctcaccgtctccccagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgagaacgtggtcatcgcctgcctggtccagggcttcttccccccagg 22396 JY8QFUQ01AXTRO productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 946 92.69 203/219 nt 92.24 202/219 nt Homsap IGHJ4*02 F 177 85.42 41/48 nt Homsap IGHD2-2*01 F 3 8 8 11 8.8.11 [2.17.38.11] CARFGPLTRPDYW in-frame - Potentially, because of detected insertion/deletion in FR3-IMGT at codon 72 of V-REGION: 'C' (1 nucleotides at position 124 to 124 in the user submitted sequence), (cause frameshift); gcctctggattcacctttaccaactatggcatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaggtattagtggtagtggtgaaaccacataccacgcagaatccgtgCaggggccggttcaccatctccagagacaactccaagaacaatctgtatctgcaaatgaacagtctgagagccgaggacacggccatttattactgtgcgagattcggaccacttactcgacctgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaaggggcccatcggtcttcccccctggcgcccctgctccaggagcacctccgagagcacagcggccctggggctgcctggtcaaggactacttcccccgaaccggtgacggtgtcgtggaactcagg 22397 JY8QFUQ01CPLK2 unproductive Homsap IGHV3-11*01 F 811 85.84 188/219 nt 85.39 187/219 nt Homsap IGHJ4*03 F (see comment) 114 70.83 34/48 nt Homsap IGHD3-16*01 F 2 8 8 X 8.8.X [2.17.38.11] CADIKLGDWCFDL## out-of-frame + Other possibilities: Homsap_IGHJ1*01 (highest number of consecutive identical nucleotides) in FR2-IMGT at codon 48 of V-REGION: 'AG' (2 nucleotides at position 60 to 61 in the user submitted sequence), (cause frameshift); cctctgaaaatcaccttcagcgaccactacatgagctggatccgccaggctccagggaaAGggggctggaatggatttcatatattagcaccagtggtaatatgatctattacgcagactctgtgaagggccgattcaccgtctccagggacaacgccaagaggtcgatgtatttgcagatgaacagtctgagagccgaggacacggccgtctatttctgtgccgatataaaactgggtgactggtgcttcgatctctgggggccgtggcaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccccaa 22398 JY8QFUQ01B7Y6H No results 22399 JY8QFUQ01CY6T7 productive Homsap IGHV1-18*01 F 885 90.65 194/214 nt Homsap IGHJ5*02 F 228 94.12 48/51 nt Homsap IGHD3-10*01 F 3 8 8 11 8.8.11 [0.17.38.11] CARVIRTNWLDPW in-frame + tggttacacctttactacctatggcgtcacctgggtgcgacaggcccctggacaagggcctgagtgggtgggatggatcagcgcttacaatggtaatacaaactctgcacagaagtttcaggacagagtcaccctgaccacagacacatccacgaacacagcctacatggaactgaggaacttgagatctgacgacacagccgtatattattgtgcgcgagtgattcggaccaactggctcgacccctggggccagggaacactggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcc 22400 JY8QFUQ01DDCM1 unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 982 94.52 207/219 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD4-23*01 ORF 1 8 8 X 8.8.X [2.17.38.11] CAKEGPTLLTRPPS##W out-of-frame + gcctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaacttttggtggtagtggtggttctacatactacgcagactccgtgaagggccggttcaccatctccagagacaattccaagaacacgctatatcttcaaatgagcagcctgagagccgaggacacggccatatacttctgtgcgaaagaaggacctacgcttctaactcgccccccctctcaactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaaactc 22401 JY8QFUQ01CKM9V No results 22402 JY8QFUQ01BN21I No results 22403 JY8QFUQ01CGCIW productive (see comment) Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 911 90.5 200/221 nt 89.59 198/221 nt Homsap IGHJ4*02 F 195 89.58 43/48 nt Homsap IGHD5-18*01 F 2 10 7 12 10.7.12 [1.17.38.11] CARHSRLVRYFEFW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'T' (1 nucleotides at position 54 to 54 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 68 to 68 in the user submitted sequence), (cause frameshift); tctctggtggctccatcaacagtggtagttatcactgggcctggatccgccagTcccccagggaaggGggctggagtggattgggagcgtctcctatggtgggaacacctactacaacccgtccctcatgagtcgagtcgacatattcgtcgacacgtccaagagtcagttgtccctgaaggtgagctctgtgaccgccgcggacacggctgtgtattactgtgcgagacattcgagactggtacggtactttgaattctggggccagggagccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22404 JY8QFUQ01CLDIN productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 949 93.52 202/216 nt 91.67 198/216 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 7 13 8.7.13 [2.17.38.11] CARGPRSRGYGMDVW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift);in CDR2-IMGT at codon 59 of V-REGION: 'GTG' (3 nucleotides at position 91 to 93 in the user submitted sequence), (do not cause frameshift);in FR3-IMGT at codon 83 of V-REGION: 'T' (1 nucleotides at position 157 to 157 in the user submitted sequence), (cause frameshift); in CDR2-IMGT, from codon 57 of V-REGION: 3 nucleotides (from position 85 in the user submitted sequence), (do not cause frameshift) gcctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggGAagggggctggaatgggtctcaactattactaGTGgtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaattTtcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggcaactcag 22405 JY8QFUQ01AUOFB No results 22406 JY8QFUQ01C3T62 productive Homsap IGHV3-7*01 F 941 92.66 202/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-2*01 F 2 8 8 11 8.8.11 [1.17.38.11] CAISSAFFSTGYW in-frame + gctctagattcacctttaggacatattggatgagttgggtccgccaagctccagggaaggggctggagtgggtggccaacataaaggaagatggaagtgagatacactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacacactgtttctccaaatgaacagcttgagagtcgatgacacggctgtgtattactgtgcgatcagtagtgccttcttctccacgggctactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttcccc 22407 JY8QFUQ01AL9R5 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 789 86.26 182/211 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-6*01 F 2 8 7 X 8.7.X [0.17.38.11] CARDSSNWSDA#FDIW out-of-frame - stop codons tggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgctttttgatatctggagccaagggacaatggtcaccgtctcttcagcatcccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22408 JY8QFUQ01BMYC6 unknown (see comment) Homsap IGHV3-48*01 F, or Homsap IGHV3-48*02 F or Homsap IGHV3-48*04 F or Homsap IGHV3-64*02 F or Homsap IGHV3-64*03 F or Homsap IGHV3-64*04 F or Homsap IGHV3-64*05 F or Homsap IGHV3-64D*06 F 121 54.48 73/134 nt 8 7 X 8.7.X [1.17.11.X] null + No rearrangement found stop codons ctctggattcaccttcagcaaccataacatgaactgggtccgccaggctccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccc 22409 JY8QFUQ01BZ3AC productive Homsap IGHV3-7*01 F 944 93.49 201/215 nt Homsap IGHJ3*02 F 196 88.0 44/50 nt Homsap IGHD6-6*01 F 2 8 8 10 8.8.10 [0.17.38.11] CVRPPGRRLDIW in-frame - ctggattcacctttagtaattattggatgacgtgggtccgccaggctccagggaaggggctggagtgggtggccaacataaatggagatggaagtgggcaacaatatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaacttactgtatctgcaaatgaacagcctgagagccgaggacactgctgtatattactgtgtgagacccccaggtcgtcgtcttgatatttggggccaagggacaatggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22410 JY8QFUQ01BKPPK unproductive Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30-5*01 F 1013 96.33 210/218 nt 95.87 209/218 nt Homsap IGHJ5*02 F (see comment) 129 72.55 37/51 nt Homsap IGHD2-2*02 F 2 8 8 X 8.8.X [1.17.38.11] CAKDRVYGGGEPLDH## out-of-frame + Other possibilities: Homsap_IGHJ4*02 (shorter alignment but highest percentage of identity) in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 61 to 61 in the user submitted sequence), (cause frameshift); cctctggattcaccttcagtagttataacatgcactgggtccgccaggctccaggcaaggGggctggagtgggtggcagttatatcatatgatggaagaaataaatactatgcagactccgtgaagggccgactcaccatctccagagacaattccaagaacatgttgtatctgcaaatgaacagcctgagacctgaggacacggctgtgtattactgtgcgaaagatcgggtctacggagggggcgagccgcttgaccactggggcccagggaaccctggtcagcgtctcctctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22411 JY8QFUQ01C81UR No results 22412 JY8QFUQ01BNXXZ No results 22413 JY8QFUQ01BOUIW productive (see comment) Homsap IGHV3-53*01 F, or Homsap IGHV3-53*02 F 876 90.19 193/214 nt 89.72 192/214 nt Homsap IGHJ4*02 F 168 83.33 40/48 nt Homsap IGHD6-19*01 F 2 8 6 15 8.6.15 [1.17.38.11] CARDQSPGVAVAGPDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT, from codon 56 of V-REGION: 1 nucleotides (from position 81 in the user submitted sequence), (cause frameshift) ttcgggggttcaccgtcagtagcaagtacatgacctgggtccgccaggctccggggaagggactggagtctgtctctgtttttatagcggtgatcaaacatactacgcagactccgtgaggggccgattcaccatctccatagacaattccaagaacacactgtatctgcaaatgaacagcctgagagccgaggacacggctgtgtattactgtgcgagagatcaaagtccgggtgtagcagtggctggtcctgattactggggccagggaaccctggtcaccgtctcctcagcatccccggaccagccccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaangtggtcgtcgcatgcctggtccagggcttcttccccc 22414 JY8QFUQ01DGOL4 unknown (see comment) Homsap IGHV3-7*01 F 1041 96.82 213/220 nt 96.36 212/220 nt 8 8 X 8.8.X [2.17.38.X] null - No rearrangement found in CDR2-IMGT at codon 57 of V-REGION: 'A' (1 nucleotides at position 87 to 87 in the user submitted sequence), (cause frameshift); agcctctggattcaggtttagcatctattggatgagctgggtccgccaggctccagggaaggggctggagtgggtggccaacataaAagcaagatggaagtgagaaatactatgtggactctgtgaagggccgattcaccatctccagagacaacgccaagaactcactgtatctgcaaatgagcagcctgagagccgaggacacggctgtgtattactcatccccgaccagccccaaggtcttcccgctgagcctcgacagcacccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccccag 22415 JY8QFUQ01CEU9H unproductive (see comment) Homsap IGHV3-48*02 F 967 94.44 204/216 nt Homsap IGHJ6*02 F 238 87.1 54/62 nt Homsap IGHD2-21*02 F 2 8 8 19 8.8.19 [1.17.38.11] CARPAGEGDPFFHYYSGLDVW in-frame - stop codons tctggattcaccttcagtagttatagcatgaactgggtccgccaggctccagggaaggggctggagtagatttcatacattagtggtagtggcggtaccatatactatgcagactctgtgaagggccgcttcaccatctccagagacaatgccaagaagtcactgtatcttcaaatggacagcctgagagacgaggacacggctgtgtattactgtgcgagacccgcgggggagggtgacccttttttccactactactccggtttggacgtctggggccaggggaccacggtcatcgtctcgtcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22416 JY8QFUQ01CWUM4 unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F or Homsap IGHV3-74*03 F 144 53.33 96/180 nt 52.78 95/180 nt 6 8 X 6.8.X [X.17.28.X] null - No rearrangement found stop codons in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift); tcatcttcagtagctactggatgcactgggtccgccaagctccagggaagGgggctggtgtgggtctcaccgtctccccagcatcccccgaccagccccaaggtcttcccgctgagcctctgagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22417 JY8QFUQ01COSIV unknown (see comment) Homsap IGHV3-74*01 F, or Homsap IGHV3-74*02 F 123 50.95 107/210 nt 8 8 X 8.8.X [1.17.35.X] null + No rearrangement found ttctggattcaccttcagtacatactggatgcactgggtccgccaagctccagggaaggggctggtgtgggtctcctcagcctccaccaagggcccatcggtcttcccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22418 JY8QFUQ01A2S3C productive (see comment) Homsap IGHV3-30*03 F, or Homsap IGHV3-30*18 F or Homsap IGHV3-30*19 F or Homsap IGHV3-30-5*01 F 870 88.64 195/220 nt 87.27 192/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD3-3*01 F 2 8 8 10 8.8.10 [2.17.38.11] CAKDFYYGCDYW in-frame + Potentially, because of detected insertion/deletion in FR2-IMGT at codon 45 of V-REGION: 'G' (1 nucleotides at position 51 to 51 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 50 of V-REGION: 'CT' (2 nucleotides at position 67 to 68 in the user submitted sequence), (cause frameshift);in FR3-IMGT at codon 74 of V-REGION: 'G' (1 nucleotides at position 132 to 132 in the user submitted sequence), (cause frameshift); agtctctggattcaacttcagtggctatggcatgcactgggtccgccaggGctccaggcaaggggcCTgggagtgggtggcagtcattgcatacaatggaggaaatatatactacgcagactccgtgaaggGgccgattcaccatctccagagacaattccaaggataccctgtacttgcacatgaccagtctgagacctgatgacacggccatgtattactgtgcgaaagacttttattatggttgcgactactggggccagggaaccctggtcaccgtctcctcagcatccccgaccagccccaaggtctcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctcggtccagggcttccttcccccgaggagccacct 22419 JY8QFUQ01BFKU7 unknown (see comment) Homsap IGHV3-11*01 F, or Homsap IGHV3-11*04 F (see comment) 541 71.69 157/219 nt Homsap IGHJ1*01 F (see comment) 22 75.0 6/8 nt 8 8 X 8.8.X [2.17.38.X] null + Rearranged sequence but no junction found Low V-REGION identity (71,69% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release The JUNCTION has not been identified: the results for J-GENE may be unreliable. gcctctgggttcaccttcagtgactactacatgggctggatccgccaggctccagggaaggggctggagtggattgcgtacattagtggtagtggtgataccatatactacgcagactctgtgaagggccgattcaccatctccaaggtcttcccgctgagcctcgacagcaccccccaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccc 22420 JY8QFUQ01AARY1 unknown (see comment) Homsap IGHV1-18*01 F, or Homsap IGHV1-18*02 (F) or Homsap IGHV1-18*03 F or Homsap IGHV7-81*01 ORF 139 58.88 63/107 nt 8 8 X 8.8.X [0.17.2.X] null - No rearrangement found cggttacattgttaccacctctggtttcagctgggtgcgacaggcccctggacaaggccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22421 JY8QFUQ01BHRCO unproductive Homsap IGHV4-61*02 F (see comment) 731 81.45 180/221 nt Homsap IGHJ4*02 F (see comment) 114 70.83 34/48 nt Homsap IGHD3-3*01 F 1 10 7 X 10.7.X [1.17.38.11] CARERAPSIDGVRELDF## out-of-frame + Low V-REGION identity (81,45% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release Other possibilities: Homsap_IGHJ4*03 (highest number of consecutive identical nucleotides) tctctggtgactccattaccagtggtttttactactggaattggatcagacagcccgccgggaggggactggagtggatcggacgtgtctatattactgggagtgtcaactacagtccatccctcgaacacagagtcagtatatctctagacacgtccaagaggcaattcttcttgaggttggtctctgtgaccgccgcagacacggccgtgtattactgtgcgagagagcgggctccttcgattgacggagtgagagaacttgacttctggggccagggggaccctggtcaccgtctccccagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22422 JY8QFUQ01CEIUR unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1105 100.0 222/222 nt 99.1 220/222 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [2.17.38.11] CARSRTFYGSANY## out-of-frame + in FR2-IMGT at codon 39 of V-REGION: 'G' (1 nucleotides at position 39 to 39 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 49 of V-REGION: 'G' (1 nucleotides at position 69 to 69 in the user submitted sequence), (cause frameshift); gtctctggtggctccatcagcagtagtagttactactgGgggctggatccgccagcccccagggaaggGggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccacaagggcccatcggtcttccccctggcaccctctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactc 22423 JY8QFUQ01CBRT1 unproductive (see comment) Homsap IGHV3-30*01 F 868 88.94 193/217 nt Homsap IGHJ3*01 F 214 92.0 46/50 nt Homsap IGHD1-14*01 ORF 3 8 8 X 8.8.X [1.17.38.11] CACGPYA#DGYDVW out-of-frame - stop codons ctctggattcaccttcagtgcctttactatgcactgggtccnccaggctccaggcgagggactagagtgggtggcagctatatcatatgatggcagtaaaaaatactatgcggactttgtgaagggccgattcaccatctccagagacaatcccaagagtacactgtatctacaaatgaacggcctgggaggtgatgacacggctttgtattactgtgcgtgcggcccatatgcgggatggttatgatgtctggggccaagggacaaaggtcaccgtctcttcagcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22424 JY8QFUQ01BK9ED unproductive Homsap IGHV4-39*01 F, or Homsap IGHV4-39*05 F 1100 100.0 221/221 nt Homsap IGHJ5*02 F 120 70.59 36/51 nt Homsap IGHD5-18*01 F 1 10 7 X 10.7.X [1.17.38.11] CARSRTFYGSANY## out-of-frame + tctctggtggctccatcagcagtagtagttactactggggctggatccgccagcccccagggaaggggctggagtggattgggagtatctattatagtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatccgtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggctgtgtattactgtgcgagaagtagaaccttctatggttcggccaactactgggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaact 22425 JY8QFUQ01AV4SA No results 22426 JY8QFUQ01BC2PX productive (see comment) Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 864 88.94 193/217 nt 88.48 192/217 nt Homsap IGHJ4*02 F 204 91.67 44/48 nt Homsap IGHD1-26*01 F 1 8 8 16 8.8.16 [1.17.38.11] CAKVMWGVTGPIDPFDYW in-frame + Potentially, because of detected insertion/deletion in CDR2-IMGT at codon 59 of V-REGION: 'G' (1 nucleotides at position 90 to 90 in the user submitted sequence), (cause frameshift); ctctggattcacgttcaatgactatgccatgagctgggtccgccaggcgccagataaggggctggagtgggtctcgactgtgagtagtaGggggtgataccacacactacgcagacttcgtgaagggccggctcaccatctccagagacaattccaggaacacactgtatctgcaaatgaacagcctgacagccgaggacacggccatatattactgtgcgaaagttatgtggggagttacaggtccaattgatccctttgactactggggccagggaaccctggtcaccgtctcctccgcatccccgaccagccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttccccca 22427 JY8QFUQ01CA2ZU No results 22428 JY8QFUQ01BLYJ4 unproductive (see comment) Homsap IGHV4-59*01 F, or Homsap IGHV4-59*07 F 809 86.51 186/215 nt 86.05 185/215 nt Homsap IGHJ3*02 F 187 86.0 43/50 nt Homsap IGHD6-6*01 F 2 8 7 X 8.7.X [1.17.38.11] CARDSSNWSDA#FDIW out-of-frame - stop codons in FR3-IMGT at codon 84 of V-REGION: 'C' (1 nucleotides at position 153 to 153 in the user submitted sequence), (cause frameshift); tctctggtggctccatgagtagtcactattggagttggatccggcaatcttcagggaagggactggagtggcttggctacatacattacagtgggagcaccaggttcaacccctccctcaacagtcgagtcaccatatcggtggacacgtccCaagagtcagttcttcctgctactgaactctgtgaccgctgcggacacggccacatattactgtgcgagagactctagcaattggtcagacgcattttgatatctggagccaagggacaatggtcaccgtctcttcagcatcccccgaccagcccccaaggtcttcccgctgagcctctgcagcacccagccagatgggaacgtggtcatcgcctgcctggtccagggcttcttcccccca 22429 JY8QFUQ01C1IBJ unproductive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 950 93.12 203/218 nt 92.2 201/218 nt Homsap IGHJ4*02 F 123 72.92 35/48 nt Homsap IGHD4-17*01 F 3 8 8 X 8.8.X [1.17.38.11] CARFGPLTRPDY## out-of-frame + in CDR1-IMGT at codon 30 of V-REGION: 'T' (1 nucleotides at position 15 to 15 in the user submitted sequence), (cause frameshift);in FR2-IMGT at codon 48 of V-REGION: 'GA' (2 nucleotides at position 58 to 59 in the user submitted sequence), (cause frameshift); cctctggattcaccTtttaccaactatggcatgagctgggtccgccaggctccagggGAagggggctggagtgggtctcaggtattagtggtagtggtgataccacataccacgcagactccgtgcagggccgattcaccatctccagagacaactccaagaacactctgtatctgcaaatgaacagtctgagagtcgaggacacggccgtttattactgtgcgagattcggcccacttactcgacctgactactgggggccagggaactttggtcaccgtctcctcagcatccccgaccagccccaaggtcttcccgctgagcctccgacagcacccccccgaagatgggaacgtggtcgtcgcatgcctggtccagggcttcttccccca 22430 JY8QFUQ01B48C0 productive Homsap IGHV3-33*05 F (see comment) 699 80.0 176/220 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD5-12*01 F 3 8 8 13 8.8.13 [2.17.38.11] CVKGRGYNDYGLDYW in-frame - Low V-REGION identity (80,00% ) this may indicate potential nucleotide insertion(s) and/or deletion(s) which are not dealt in this release gcgtctgggattctccttcagcaattatgccatccactgggtccgccaggctccaggcaaggggctggagtgggtggcgaccatttcatatgatattaataaaagatattatgcagagtccgtgaggggccgattcaccctctccagagacaattccaagaacactctcgatctgctcatggatacccttcggttcgacgacacggctgtctattattgtgttaaaggacgtggatacaatgactacggcctcgactactggggcccgggaaccctgctcaccgtctcctcagcctccaccaagggcccatcggtcttcccccctggcaccctcctccaagagcacctctggggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactca 22431 JY8QFUQ01BLN4B productive Homsap IGHV3-33*01 F, or Homsap IGHV3-33*06 F 851 88.07 192/218 nt Homsap IGHJ6*01 F (see comment) 171 74.6 47/63 nt Homsap IGHD2-2*01 F 1 8 8 13 8.8.13 [1.17.38.11] CVSDRELHYQHLDVW in-frame + Other possibilities: Homsap_IGHJ3*01 (shorter alignment but highest percentage of identity) cgtctggattcaacttcaatagttttggcatgcactgggtccgccaggctccgggcaagggactggagtgggtggcaaacatatggtatgatggaggtagtcaacactatgcagacctcgtgaagggccgattcaccatctctagagacaattccaagaacatcttgttcctgcaaatgagcgacctgagagccgaggacacggctgtttattattgtgtgagcgatagagaactccattaccagcatttggacgtctggggtcaagggaccacggtcatcgtctcatcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggccacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22432 JY8QFUQ01ARNFI productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 860 88.53 193/218 nt Homsap IGHJ4*02 F 186 87.5 42/48 nt Homsap IGHD2-15*01 F 3 8 8 14 8.8.14 [1.17.38.11] CAKEEGATGVYYVDHW in-frame + cctctggattcacctttaccacctccgccatggcctgggtccgccaggttccagggaaggggctggagtgggtctcaactattagacctagtggtgagagaacctactacgcagagtccgtgaggggccgcttcaccatctccagagacaattccgagaacacgttgtatctacaactgaacaacctgagagtcgaggacacggccatatattactgtgcgaaggaggaaggtgctactggagtctattatgttgaccactggggccagggaacccgggtcaccgtctcctcatcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcag 22433 JY8QFUQ01CDTOM productive Homsap IGHV3-23*01 F, or Homsap IGHV3-23*04 F or Homsap IGHV3-23D*01 F or Homsap IGHV3-23D*02 F 959 93.58 204/218 nt Homsap IGHJ6*02 F 220 83.87 52/62 nt Homsap IGHD5-12*01 F 2 8 8 13 8.8.13 [1.17.38.11] CARGPRSRGYGMDVW in-frame + cctctggattcaccttcaacaactatgccatgagttgggtccgccaggctccagggaaggggctggaatgggtctcaactattactagtggtggtggtagtacattgtacgcagactccgtgaagggccggttcaccatctccagagacaatttcaaggacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgagagggcctcgatcgcgcggctacggtatggacgtctggggccaagggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcgcccctggggcgcctggtcaaggactaccttccccgaaccggtgagtgtcgtggaact